miRTarBase - #MIRT102959


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pre-miRNA Information
pre-miRNA hsa-mir-548c   
Genomic Coordinates chr12: 64622509 - 64622605
Description Homo sapiens miR-548c stem-loop
Comment Extensive cloning studies suggest that the 5' miRNA may be the predominant one .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-548c-3p
Sequence 61| CAAAAAUCUCAAUUACUUUUGC |82
Evidence Experimental
Experiments SAGE
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN23013696 22 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1396767933 3 dbSNP
rs1314622460 7 dbSNP
rs1226739912 9 dbSNP
rs780547012 11 dbSNP
rs747421587 12 dbSNP
rs1298302643 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol EN2   
Synonyms -
Description engrailed homeobox 2
Transcript NM_001427   
Expression
Putative miRNA Targets on EN2
3'UTR of EN2
(miRNA target sites are highlighted)		 
>EN2|NM_001427|3'UTR
   1 GGCGGGGGGCATGGAGGCCAGGTCTCAGTCCGCGCTAAACAATGCAATAATTTAAAATCATAAAGGGCCAGTGTATAAAG
  81 ATTATACCAGCATTAATAGTGAAAATATTGTGTATTAGCTAAGGTTCTGAAATATTCTATGTATATATCATTTACAGGTG
 161 GTATAAAATCCAAAATATCTGACTATAAAATATTTTTTTGAGTTTTTTGTGTTTATGAGATTATGCTAATTTTATGGGTT
 241 TTTTTCTTTTTTGCGAAGGGGGCTGCTTAGGGTTTCACCTTTTTTTAATCCCCTAAGCTCCATTATATGACATTGGACAC
 321 TTTTTTATTATTCCAAAAGAAGAAAAAATTAAAACAACTTGCTGAAGTCCAAAGATTTTTTATTGCTGCATTTCACACAA
 401 CTGTGAACCGAATAAATAGCTCCTATTTGGTCTATGACTTCTGCCACTTTGTTTGTGTTGGCTTGGTGAGGACAGCAGGA
 481 GGGGCCCACACCTCAAGCCTGGACCAGCCACCTCAAGGCCTTGGGGAGCTTAGGGGACCTGGTGGGAGAGAGGGGACTTC
 561 CAGGGTCCTTGGGCCAGTTCTGGGATTTGGCCCTGGGAAGCAGCCCAGCGTACCCCAGGCCTGCTCTGGGAAGTCGGCTC
 641 CATGCTCACCAGCAGCCGCCCAGGCCCGCAGCCTCACCCGGCTCCCTCTCCTCACCCTCCTGCACCTAACTCCCTCCTCC
 721 TTCTCCTTTTTCCTCCTCTTCCTCCTTCCTCCTTCCTCCTGCTCCTCCTTTCTTCTTCTTTTTCTTCTCCTCCTCCTCCT
 801 TCCTTCCTCCTCCTCCTTCTCTTTCCTCCTCCTCCTCACCAAGGGCCCAACCGTGTGCATACATCGTCTGCGTCTGTGGT
 881 CTGTGTCGCTGTCCCCAGTCCCACCGCAGTCCTGCCGCAGGCCTAACCCTCCTGCCCTGGGCACTGCCTCCATGCAGAAG
 961 CGCTTCGAGGTTCTGGGGCTAAAGGCCTGGGGTGTGTGGCCTAAAGCCCAAGAGCGGTGGGGCGACCCTCCTTTTGGCTT
1041 GGCCCCAGGAATTTCCTGTGACTCCACCAGCCATCATGGGTGCCAGCCAGGGTCCCAGAAATGAGGCCATGGCTCACTGT
1121 TTCTGGGCGGGCAGAAGGCTCTGTAGAGGGAGATGGCATCATCTATCTTCCTTTCCTTTTTCTTTTCTTCCCTATTTTTT
1201 TCTTTTTTTCCTTTATTTTTTTCTTTTCTTGGAGTGGCTGCTTCTGCTATAGAGAACATTCTTCCAAGATAAATATGTGT
1281 GTTTACACATATGTCTGCATGCATGTGAACACACACACACACACACACACACCAGGCGTGTTTGAGTCCACAGTTCTGAA
1361 ACATGTGGCTACCTTGTCTTTCAAAAGAACTCAGAATCCTCCAGGATCTAGAAGAAGGAAGAAAGTGTGTAAATAATCAT
1441 TTCTTATCATCACTTTTTGTCTTTTCTTGTTTTTTAAAATATACATTTTATTTTTGAAGGTGTGGTACAGTGTAAATTAA
1521 ATATATTCAATATATTTCCCACCAAGTACCTATATATGTATATAAACAAACACATTATCTATATATAACGCCACACTGTC
1601 TTCTGTTTAGTGTATGGGGAAAGACCAATCCAACTGTCCATCTGTGGCTGGGACAGCCCAGGGGGTGTGCCCACGGCTGA
1681 CCCAGGGGTGTGCACACGGCTGAGCTGGGAGTCCCGCTGGTCTCCCTGAGGACTGAGGGTGAACTTCGCTCTTTGCCTTA
1761 AACCTCTTTATTTCATTGCAGTAATAGTTTTACGTTGTACATAATAGTGTAAACCTTTTTAAAAAGGAAAGTATAAAAAC
1841 AAAAGTTGTAATTTAAAAGTCTGAATAACCATCTGCTGCTTAGGAAACTCAATGAAATGACATGCCTTTTTAGCAGGAAG
1921 CAAAGTTGGTTTCTGTTTTTTGTTTTCTTTGTTGTTTTAGTTTATAAAACATGTGCATTTTACAGTTCCAGTATCAAATA
2001 TTTATAATCTTATGAGAAATGAATGAATGTTTCTATTTACAACTGTGCTTATCAAAATTGTGAACACCCCCACCCCCGCA
2081 TTTTTGTGTGTTGAAATTCTTGAAGGTTACATTAAATAAAACAAAATCTCTTTATTATAAAATAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cguUUUCA--UUAACUCUAAAAAc 5'
             :||||  ||   |||||||| 
Target 5' gctGAAGTCCAA---AGATTTTTt 3'
 361 - 381 154.00 -6.20
2 
miRNA  3' cguUUUCAU----UAACUCUAAAAAc 5'
             ||| ||     ||||| ||||| 
Target 5' tatAAAATATTTTTTTGAGTTTTTTg 3'
 184 - 209 133.00 -7.80
3 
miRNA  3' cguUUUCA--UUAACUCUAAAAAc 5'
             |||||  : ||  | ||||| 
Target 5' agcAAAGTTGGTTTCTGTTTTTTg 3'
 1919 - 1942 125.00 -9.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31534552 130 COSMIC
COSN31535848 191 COSMIC
COSN31547503 233 COSMIC
COSN31548708 239 COSMIC
COSN26159185 264 COSMIC
COSN28475187 287 COSMIC
COSN31594754 287 COSMIC
COSN30542904 292 COSMIC
COSN29886470 303 COSMIC
COSN31529241 343 COSMIC
COSN31606872 348 COSMIC
COSN8516092 363 COSMIC
COSN31545077 370 COSMIC
COSN31484736 406 COSMIC
COSN31534271 490 COSMIC
COSN8516093 494 COSMIC
COSN31778636 623 COSMIC
COSN30028753 968 COSMIC
COSN9978896 1427 COSMIC
COSN4614409 1447 COSMIC
COSN21945636 1874 COSMIC
COSN31541739 1922 COSMIC
COSN31515461 2003 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs773232233 1 dbSNP
rs1310527321 2 dbSNP
rs1374372239 3 dbSNP
rs12674067 4 dbSNP
rs375061145 5 dbSNP
rs778233930 6 dbSNP
rs748145360 7 dbSNP
rs758237125 8 dbSNP
rs1269751001 9 dbSNP
rs907322589 10 dbSNP
rs549356337 13 dbSNP
rs1034315317 17 dbSNP
rs1278262129 19 dbSNP
rs777673362 30 dbSNP
rs1217945069 32 dbSNP
rs992170679 33 dbSNP
rs369675027 34 dbSNP
rs192274449 35 dbSNP
rs775869823 37 dbSNP
rs1436214795 46 dbSNP
rs764108512 48 dbSNP
rs766755955 60 dbSNP
rs184624346 68 dbSNP
rs1239101784 74 dbSNP
rs1334712409 79 dbSNP
rs1199254321 90 dbSNP
rs1305783936 91 dbSNP
rs1427318595 92 dbSNP
rs374181653 94 dbSNP
rs1404050890 115 dbSNP
rs967223768 118 dbSNP
rs571482119 125 dbSNP
rs927748641 136 dbSNP
rs1469669366 144 dbSNP
rs539240179 147 dbSNP
rs988095476 151 dbSNP
rs1451883079 157 dbSNP
rs1480888929 159 dbSNP
rs954649049 164 dbSNP
rs1286973743 177 dbSNP
rs1220595628 186 dbSNP
rs1286235851 192 dbSNP
rs923061847 192 dbSNP
rs1205707178 193 dbSNP
rs1349327765 193 dbSNP
rs933169858 193 dbSNP
rs1224912739 199 dbSNP
rs1282511813 203 dbSNP
rs1345780562 203 dbSNP
rs1343528652 204 dbSNP
rs1050287156 206 dbSNP
rs1434720088 211 dbSNP
rs1225013671 216 dbSNP
rs910293796 229 dbSNP
rs985847319 235 dbSNP
rs1319536694 238 dbSNP
rs1307066217 239 dbSNP
rs1386455435 239 dbSNP
rs1400704354 239 dbSNP
rs941788086 239 dbSNP
rs554132267 240 dbSNP
rs1037352880 241 dbSNP
rs897507892 247 dbSNP
rs910196294 249 dbSNP
rs572702916 254 dbSNP
rs754062814 255 dbSNP
rs73734533 256 dbSNP
rs1013705140 258 dbSNP
rs930159695 262 dbSNP
rs1047714427 264 dbSNP
rs1277445615 271 dbSNP
rs866046119 272 dbSNP
rs1217173800 273 dbSNP
rs1267431275 280 dbSNP
rs1481893986 281 dbSNP
rs1363672714 287 dbSNP
rs1430569657 287 dbSNP
rs1339313889 288 dbSNP
rs1177914407 289 dbSNP
rs1023794568 291 dbSNP
rs969434008 312 dbSNP
rs1000929808 313 dbSNP
rs1032736345 314 dbSNP
rs1168309070 321 dbSNP
rs956737895 321 dbSNP
rs1246078538 325 dbSNP
rs1407347666 325 dbSNP
rs1185392817 328 dbSNP
rs1461365945 332 dbSNP
rs1417566824 336 dbSNP
rs1236453621 338 dbSNP
rs1207501674 339 dbSNP
rs928828584 341 dbSNP
rs1165644541 343 dbSNP
rs1386888121 348 dbSNP
rs988423002 362 dbSNP
rs938708501 363 dbSNP
rs1425107326 375 dbSNP
rs1474974200 376 dbSNP
rs759986176 383 dbSNP
rs189436701 384 dbSNP
rs985948117 386 dbSNP
rs1378444429 392 dbSNP
rs1301183687 396 dbSNP
rs1444577842 398 dbSNP
rs1170064593 409 dbSNP
rs181376144 410 dbSNP
rs207468873 420 dbSNP
rs910410056 421 dbSNP
rs1444287693 435 dbSNP
rs1055905816 438 dbSNP
rs1298255740 444 dbSNP
rs1412368576 457 dbSNP
rs894450562 462 dbSNP
rs1221736806 463 dbSNP
rs1011610846 468 dbSNP
rs775639494 469 dbSNP
rs557801689 471 dbSNP
rs928991038 474 dbSNP
rs779579742 481 dbSNP
rs903137804 485 dbSNP
rs1057241978 490 dbSNP
rs1359672471 492 dbSNP
rs1245763701 497 dbSNP
rs896727713 499 dbSNP
rs185936495 520 dbSNP
rs368761266 526 dbSNP
rs1374203516 529 dbSNP
rs1307636750 532 dbSNP
rs1045193100 539 dbSNP
rs532304607 542 dbSNP
rs1304741467 543 dbSNP
rs1425167490 545 dbSNP
rs1349256415 546 dbSNP
rs954588013 563 dbSNP
rs1479672449 566 dbSNP
rs1408167493 570 dbSNP
rs1189073885 571 dbSNP
rs372780297 575 dbSNP
rs368291486 578 dbSNP
rs1017337561 580 dbSNP
rs1162763866 581 dbSNP
rs1223732992 588 dbSNP
rs559329863 595 dbSNP
rs957044299 598 dbSNP
rs144219267 600 dbSNP
rs1030774983 602 dbSNP
rs1170999187 605 dbSNP
rs1353445524 606 dbSNP
rs973083580 609 dbSNP
rs1443987608 610 dbSNP
rs56651365 611 dbSNP
rs1387104185 613 dbSNP
rs548222421 617 dbSNP
rs951684385 620 dbSNP
rs986063105 621 dbSNP
rs143878581 624 dbSNP
rs3808330 626 dbSNP
rs1430939279 629 dbSNP
rs1364458606 631 dbSNP
rs928770495 636 dbSNP
rs938842027 637 dbSNP
rs1265787776 643 dbSNP
rs1188733321 644 dbSNP
rs762442195 646 dbSNP
rs1055873298 648 dbSNP
rs531617980 658 dbSNP
rs1325802975 659 dbSNP
rs916020322 660 dbSNP
rs929083457 661 dbSNP
rs1205712467 663 dbSNP
rs549831481 668 dbSNP
rs947367806 669 dbSNP
rs1383803129 670 dbSNP
rs1365884482 675 dbSNP
rs992494541 678 dbSNP
rs1263822768 679 dbSNP
rs1461040833 680 dbSNP
rs1181915894 681 dbSNP
rs1465241135 685 dbSNP
rs916939115 686 dbSNP
rs1173020809 687 dbSNP
rs1235542829 688 dbSNP
rs1187279987 689 dbSNP
rs949618173 702 dbSNP
rs1186860099 703 dbSNP
rs1045305206 704 dbSNP
rs3808329 705 dbSNP
rs1463988892 710 dbSNP
rs189617846 714 dbSNP
rs1296760733 718 dbSNP
rs1384284079 720 dbSNP
rs554342116 720 dbSNP
rs751121930 721 dbSNP
rs936836648 723 dbSNP
rs1299569545 727 dbSNP
rs3808328 731 dbSNP
rs1390009026 738 dbSNP
rs569397767 738 dbSNP
rs892536980 740 dbSNP
rs1369081543 747 dbSNP
rs536927665 748 dbSNP
rs10234087 751 dbSNP
rs1252897504 752 dbSNP
rs1007371839 753 dbSNP
rs867936846 756 dbSNP
rs576070635 758 dbSNP
rs1269961636 762 dbSNP
rs1226012682 763 dbSNP
rs111556743 768 dbSNP
rs371995609 768 dbSNP
rs537053165 768 dbSNP
rs1284235056 770 dbSNP
rs769254190 770 dbSNP
rs1338242955 775 dbSNP
rs1308678032 781 dbSNP
rs1017308405 783 dbSNP
rs1007448451 787 dbSNP
rs1410124484 787 dbSNP
rs890474287 787 dbSNP
rs1284015816 788 dbSNP
rs926736266 791 dbSNP
rs1163236401 793 dbSNP
rs574162792 794 dbSNP
rs1471841546 795 dbSNP
rs1322851073 796 dbSNP
rs1365672320 797 dbSNP
rs554226119 799 dbSNP
rs1286659906 804 dbSNP
rs938056066 804 dbSNP
rs1447776890 805 dbSNP
rs1453154307 805 dbSNP
rs1209226578 809 dbSNP
rs139789685 810 dbSNP
rs745455365 813 dbSNP
rs1026596115 815 dbSNP
rs574133828 816 dbSNP
rs3808327 819 dbSNP
rs1476803838 820 dbSNP
rs1201429485 821 dbSNP
rs1026362293 823 dbSNP
rs1429410671 824 dbSNP
rs386719925 824 dbSNP
rs55729502 825 dbSNP
rs3808326 826 dbSNP
rs1387164502 827 dbSNP
rs950429828 836 dbSNP
rs979774405 841 dbSNP
rs1409995721 846 dbSNP
rs1400921832 848 dbSNP
rs574574146 853 dbSNP
rs1035972064 854 dbSNP
rs960175313 855 dbSNP
rs562841947 864 dbSNP
rs1407319846 867 dbSNP
rs915989220 871 dbSNP
rs1304239817 872 dbSNP
rs1345400156 873 dbSNP
rs57599144 881 dbSNP
rs947418496 888 dbSNP
rs978870764 889 dbSNP
rs1346066892 895 dbSNP
rs1274648912 896 dbSNP
rs1231223905 903 dbSNP
rs1434884996 903 dbSNP
rs924579277 906 dbSNP
rs563259530 907 dbSNP
rs934709633 908 dbSNP
rs375798987 909 dbSNP
rs1386622355 913 dbSNP
rs1283315493 916 dbSNP
rs1415259912 917 dbSNP
rs531561890 918 dbSNP
rs1476940982 925 dbSNP
rs1224677785 928 dbSNP
rs1052097533 929 dbSNP
rs1464043063 934 dbSNP
rs113000817 935 dbSNP
rs1490161371 937 dbSNP
rs549768076 938 dbSNP
rs1442668319 940 dbSNP
rs1278317353 946 dbSNP
rs1217804556 950 dbSNP
rs1017652160 954 dbSNP
rs370047096 956 dbSNP
rs899070019 961 dbSNP
rs564987207 962 dbSNP
rs890412165 963 dbSNP
rs143914514 967 dbSNP
rs992558418 970 dbSNP
rs768516312 973 dbSNP
rs1426991721 978 dbSNP
rs1038810914 979 dbSNP
rs1304108903 981 dbSNP
rs368877872 985 dbSNP
rs1448802074 990 dbSNP
rs1387736795 991 dbSNP
rs1183131494 992 dbSNP
rs4716597 994 dbSNP
rs1236515287 995 dbSNP
rs1385589834 1004 dbSNP
rs1330985573 1010 dbSNP
rs994970243 1013 dbSNP
rs969812220 1015 dbSNP
rs181828936 1016 dbSNP
rs369546982 1017 dbSNP
rs1003232028 1024 dbSNP
rs1361825958 1025 dbSNP
rs1228938774 1026 dbSNP
rs990151070 1028 dbSNP
rs1282635351 1032 dbSNP
rs1372110632 1044 dbSNP
rs1247966109 1056 dbSNP
rs771068607 1072 dbSNP
rs960312452 1075 dbSNP
rs991747297 1076 dbSNP
rs1166892488 1077 dbSNP
rs945538430 1080 dbSNP
rs1051973678 1083 dbSNP
rs911971501 1088 dbSNP
rs1473376469 1106 dbSNP
rs1252931656 1119 dbSNP
rs1023099244 1124 dbSNP
rs1181871934 1128 dbSNP
rs968889093 1129 dbSNP
rs114134796 1130 dbSNP
rs570366558 1142 dbSNP
rs924742692 1151 dbSNP
rs1230409115 1166 dbSNP
rs575380918 1167 dbSNP
rs1039035249 1177 dbSNP
rs1351374971 1178 dbSNP
rs767302964 1194 dbSNP
rs1408971594 1195 dbSNP
rs899181623 1195 dbSNP
rs67027007 1196 dbSNP
rs1348734793 1197 dbSNP
rs1162117442 1201 dbSNP
rs1048117397 1203 dbSNP
rs1412223518 1203 dbSNP
rs1458394609 1203 dbSNP
rs1181082560 1210 dbSNP
rs1446071138 1210 dbSNP
rs558576352 1212 dbSNP
rs1471811550 1214 dbSNP
rs1164689990 1216 dbSNP
rs1269913574 1216 dbSNP
rs1192221148 1234 dbSNP
rs1384930410 1238 dbSNP
rs911902548 1247 dbSNP
rs1192843404 1250 dbSNP
rs886236467 1260 dbSNP
rs186374442 1280 dbSNP
rs1024118951 1290 dbSNP
rs969759971 1291 dbSNP
rs10949811 1299 dbSNP
rs1303155127 1301 dbSNP
rs1387229806 1306 dbSNP
rs1479263303 1308 dbSNP
rs113684257 1309 dbSNP
rs1173755778 1309 dbSNP
rs1423662950 1309 dbSNP
rs1433012003 1309 dbSNP
rs144874127 1309 dbSNP
rs1456281625 1309 dbSNP
rs763703116 1309 dbSNP
rs878956775 1309 dbSNP
rs1465401204 1315 dbSNP
rs1329374003 1322 dbSNP
rs1206998129 1323 dbSNP
rs1032610501 1324 dbSNP
rs957268397 1326 dbSNP
rs989709712 1328 dbSNP
rs72022210 1329 dbSNP
rs762287109 1330 dbSNP
rs767236772 1330 dbSNP
rs879253454 1330 dbSNP
rs35869460 1331 dbSNP
rs77385528 1331 dbSNP
rs200149777 1334 dbSNP
rs1038948000 1335 dbSNP
rs1393733170 1338 dbSNP
rs1170962215 1339 dbSNP
rs1450654824 1343 dbSNP
rs1389580632 1345 dbSNP
rs1339596740 1353 dbSNP
rs1186791069 1363 dbSNP
rs1425677860 1364 dbSNP
rs898973780 1365 dbSNP
rs534694938 1373 dbSNP
rs1257106688 1374 dbSNP
rs552815057 1377 dbSNP
rs1482767146 1381 dbSNP
rs1047914226 1387 dbSNP
rs1277940498 1405 dbSNP
rs1253044695 1412 dbSNP
rs886226745 1415 dbSNP
rs1224588025 1417 dbSNP
rs752356970 1423 dbSNP
rs1341809736 1424 dbSNP
rs1339968221 1426 dbSNP
rs574540870 1439 dbSNP
rs1312987017 1446 dbSNP
rs190966205 1461 dbSNP
rs987625350 1464 dbSNP
rs1228316125 1466 dbSNP
rs1310262656 1476 dbSNP
rs560665142 1481 dbSNP
rs117213382 1483 dbSNP
rs1013150742 1495 dbSNP
rs1369131977 1500 dbSNP
rs1023252481 1503 dbSNP
rs1474360069 1506 dbSNP
rs969274455 1507 dbSNP
rs1242944864 1509 dbSNP
rs1000408413 1510 dbSNP
rs1483286887 1511 dbSNP
rs1273813302 1513 dbSNP
rs1032165907 1517 dbSNP
rs1194075287 1518 dbSNP
rs1357773666 1527 dbSNP
rs1243551581 1530 dbSNP
rs1265532045 1530 dbSNP
rs1353211731 1539 dbSNP
rs956117296 1543 dbSNP
rs1289879850 1547 dbSNP
rs1410804534 1548 dbSNP
rs920574365 1551 dbSNP
rs1327357707 1560 dbSNP
rs1195743663 1563 dbSNP
rs930643638 1564 dbSNP
rs545735475 1569 dbSNP
rs1459975151 1576 dbSNP
rs1414436676 1582 dbSNP
rs1160252408 1584 dbSNP
rs886340171 1586 dbSNP
rs1014148152 1587 dbSNP
rs549371674 1590 dbSNP
rs1453279842 1591 dbSNP
rs1267388802 1592 dbSNP
rs911871268 1615 dbSNP
rs1001204587 1624 dbSNP
rs964693575 1637 dbSNP
rs370953015 1645 dbSNP
rs974616858 1647 dbSNP
rs1400295624 1651 dbSNP
rs1328844395 1652 dbSNP
rs1465847417 1654 dbSNP
rs973562325 1657 dbSNP
rs758514907 1660 dbSNP
rs1332145607 1661 dbSNP
rs1297439496 1663 dbSNP
rs1323533891 1672 dbSNP
rs920737400 1672 dbSNP
rs182759274 1675 dbSNP
rs967347278 1676 dbSNP
rs920532792 1680 dbSNP
rs987741684 1682 dbSNP
rs1325010393 1684 dbSNP
rs1019095925 1686 dbSNP
rs1203942234 1687 dbSNP
rs1378113616 1689 dbSNP
rs1192996088 1693 dbSNP
rs1466697631 1694 dbSNP
rs1249360154 1695 dbSNP
rs930468327 1698 dbSNP
rs547832038 1699 dbSNP
rs974787694 1710 dbSNP
rs1221270457 1714 dbSNP
rs1346219361 1716 dbSNP
rs559599005 1717 dbSNP
rs939074223 1720 dbSNP
rs1056242986 1724 dbSNP
rs930771515 1726 dbSNP
rs753280242 1734 dbSNP
rs983837287 1735 dbSNP
rs907886460 1738 dbSNP
rs1262782708 1739 dbSNP
rs1343624524 1740 dbSNP
rs894800549 1742 dbSNP
rs949940593 1748 dbSNP
rs530265860 1749 dbSNP
rs1172871242 1750 dbSNP
rs1452527612 1755 dbSNP
rs1391436380 1761 dbSNP
rs1188603165 1766 dbSNP
rs1431577591 1780 dbSNP
rs1474821595 1780 dbSNP
rs1239987249 1792 dbSNP
rs118079538 1794 dbSNP
rs937171804 1795 dbSNP
rs1054329027 1801 dbSNP
rs892864304 1802 dbSNP
rs1344981768 1806 dbSNP
rs1299046733 1808 dbSNP
rs1214039942 1815 dbSNP
rs1360029012 1815 dbSNP
rs1449044890 1817 dbSNP
rs1455535997 1818 dbSNP
rs1044665882 1827 dbSNP
rs762503040 1828 dbSNP
rs1312083780 1829 dbSNP
rs570301953 1831 dbSNP
rs1399352700 1832 dbSNP
rs1010011741 1833 dbSNP
rs904808199 1840 dbSNP
rs1408855916 1845 dbSNP
rs537790903 1849 dbSNP
rs1347292802 1854 dbSNP
rs780620119 1869 dbSNP
rs570871717 1870 dbSNP
rs146402842 1874 dbSNP
rs1000865535 1893 dbSNP
rs552933923 1899 dbSNP
rs1223650937 1904 dbSNP
rs778165644 1905 dbSNP
rs538621101 1906 dbSNP
rs573063000 1918 dbSNP
rs956424101 1922 dbSNP
rs1484269800 1941 dbSNP
rs547419446 1946 dbSNP
rs1019211456 1961 dbSNP
rs1310145999 1968 dbSNP
rs1229063444 1971 dbSNP
rs760202583 1971 dbSNP
rs1334403710 1972 dbSNP
rs1291713382 1977 dbSNP
rs34901594 1988 dbSNP
rs1261696259 1997 dbSNP
rs975300984 2006 dbSNP
rs1352173215 2008 dbSNP
rs1298608926 2010 dbSNP
rs1441411428 2013 dbSNP
rs139745969 2014 dbSNP
rs1166336726 2017 dbSNP
rs1405489973 2018 dbSNP
rs952202619 2022 dbSNP
rs186998101 2026 dbSNP
rs1019013113 2036 dbSNP
rs1271739746 2042 dbSNP
rs1177084639 2048 dbSNP
rs115156116 2049 dbSNP
rs568068965 2060 dbSNP
rs950056731 2062 dbSNP
rs1222369213 2064 dbSNP
rs749917963 2068 dbSNP
rs373820948 2070 dbSNP
rs983776561 2074 dbSNP
rs755786194 2078 dbSNP
rs535221848 2079 dbSNP
rs1223107551 2087 dbSNP
rs1371057312 2091 dbSNP
rs945758995 2092 dbSNP
rs1440988703 2093 dbSNP
rs1041477866 2106 dbSNP
rs1056209050 2107 dbSNP
rs1458508413 2113 dbSNP
rs1413109112 2114 dbSNP
rs1158795228 2127 dbSNP
rs1417753567 2129 dbSNP
rs56178493 2131 dbSNP
rs1192349651 2135 dbSNP
rs1156592359 2138 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 2020.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 2020.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065670. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000297375.4 | 3UTR | UCCAAAGAUUUUUUAUUGCUGCAUUUCACACAACUGUGAACCG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1065670
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / 4-thiouridine, 3_ML_LG
Location of target site ENST00000297375.4 | 3UTR | AAGUCCAAAGAUUUUUUAUUGCUGCAUUUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE32688 Pancreatic cancer 0.534 8.2e-4 0.119 2.6e-1 32 Click to see details
GSE21032 Prostate cancer 0.326 1.3e-3 0.331 1.1e-3 83 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.521 3.8e-3 0.533 3.0e-3 25 Click to see details
GSE14794 Lymphoblastoid cells 0.277 4.1e-3 0.305 1.7e-3 90 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.447 1.3e-2 0.349 4.4e-2 25 Click to see details
GSE19783 ER- ER- breast cancer 0.208 3.3e-2 0.168 6.9e-2 79 Click to see details
GSE19536 Breast cancer 0.182 3.5e-2 0.145 7.5e-2 100 Click to see details
GSE17306 Multiple myeloma -0.252 4.0e-2 -0.256 3.8e-2 49 Click to see details
GSE28544 Breast cancer -0.351 4.6e-2 -0.430 1.8e-2 24 Click to see details
GSE15076 Monocyte-derived dendritic cells -0.616 5.2e-2 -0.690 2.9e-2 8 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.232 1.6e-1 0.164 2.4e-1 20 Click to see details
GSE26953 Aortic valvular endothelial cells 0.174 2.1e-1 0.244 1.3e-1 24 Click to see details
GSE21849 B cell lymphoma 0.156 2.1e-1 0.267 8.1e-2 29 Click to see details
GSE27834 Pluripotent stem cells -0.209 2.2e-1 -0.118 3.3e-1 16 Click to see details
GSE38226 Liver fibrosis -0.175 2.2e-1 -0.652 6.8e-4 21 Click to see details
GSE19350 CNS germ cell tumors -0.239 2.3e-1 0.196 2.7e-1 12 Click to see details
GSE17498 Multiple myeloma 0.117 2.4e-1 0.102 2.7e-1 40 Click to see details
GSE19783 ER+ ER+ breast cancer 0.161 2.5e-1 0.203 2.0e-1 20 Click to see details
GSE28260 Renal cortex and medulla -0.14 3.2e-1 -0.021 4.7e-1 13 Click to see details
GSE42095 Differentiated embryonic stem cells 0.096 3.3e-1 0.063 3.9e-1 23 Click to see details
GSE21687 Ependynoma primary tumors -0.002 4.9e-1 -0.028 4.1e-1 64 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
459 hsa-miR-548c-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055126 SCD stearoyl-CoA desaturase 2 2
MIRT055360 PDCD4 programmed cell death 4 2 2
MIRT057340 PANK1 pantothenate kinase 1 2 2
MIRT058532 PRDM10 PR/SET domain 10 2 2
MIRT064700 CCND2 cyclin D2 2 4
MIRT068070 SPATA13 spermatogenesis associated 13 2 4
MIRT069438 CDCA4 cell division cycle associated 4 2 4
MIRT070546 EXOC5 exocyst complex component 5 2 2
MIRT070866 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT071492 CALM1 calmodulin 1 2 6
MIRT077694 ZNF652 zinc finger protein 652 2 2
MIRT078290 RPS6KB1 ribosomal protein S6 kinase B1 2 2
MIRT080233 SMAD4 SMAD family member 4 2 6
MIRT080612 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 8
MIRT081130 LDLR low density lipoprotein receptor 2 6
MIRT083622 NCOA3 nuclear receptor coactivator 3 2 2
MIRT088674 EML4 echinoderm microtubule associated protein like 4 2 4
MIRT089617 MAT2A methionine adenosyltransferase 2A 2 2
MIRT091138 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT091699 TGFBR2 transforming growth factor beta receptor 2 2 4
MIRT093590 SPCS3 signal peptidase complex subunit 3 2 2
MIRT096243 CANX calnexin 2 2
MIRT099747 SOX4 SRY-box 4 2 6
MIRT101977 EPHA7 EPH receptor A7 2 4
MIRT102959 EN2 engrailed homeobox 2 2 4
MIRT107464 NFIB nuclear factor I B 2 2
MIRT107876 FXN frataxin 2 2
MIRT110174 ZNF711 zinc finger protein 711 2 2
MIRT115410 UNKL unkempt family like zinc finger 2 4
MIRT121611 LMNB1 lamin B1 2 2
MIRT130394 PTPRJ protein tyrosine phosphatase, receptor type J 2 2
MIRT134673 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT142311 RBBP6 RB binding protein 6, ubiquitin ligase 2 2
MIRT165349 AFF4 AF4/FMR2 family member 4 2 2
MIRT165649 DCTN4 dynactin subunit 4 2 2
MIRT166971 FCHO2 FCH domain only 2 2 2
MIRT176163 PGK1 phosphoglycerate kinase 1 2 2
MIRT181740 UHMK1 U2AF homology motif kinase 1 2 4
MIRT186876 CCNT1 cyclin T1 2 2
MIRT187285 DAZAP2 DAZ associated protein 2 2 2
MIRT188824 TMTC3 transmembrane and tetratricopeptide repeat containing 3 2 4
MIRT196761 CRLF3 cytokine receptor like factor 3 2 2
MIRT200994 ZNF805 zinc finger protein 805 2 4
MIRT203681 DIP2A disco interacting protein 2 homolog A 2 2
MIRT206304 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT208377 SLC25A36 solute carrier family 25 member 36 2 2
MIRT211083 C4ORF32 family with sequence similarity 241 member A 2 2
MIRT211231 FGF2 fibroblast growth factor 2 2 6
MIRT212651 SH3BP2 SH3 domain binding protein 2 2 2
MIRT217310 FOXO3 forkhead box O3 2 2
MIRT218910 GLO1 glyoxalase I 2 4
MIRT223962 TRPS1 transcriptional repressor GATA binding 1 2 2
MIRT242382 TMC5 transmembrane channel like 5 2 2
MIRT262836 CCDC6 coiled-coil domain containing 6 2 2
MIRT264533 TARDBP TAR DNA binding protein 2 6
MIRT273412 SLC11A2 solute carrier family 11 member 2 2 2
MIRT274711 CPSF6 cleavage and polyadenylation specific factor 6 2 2
MIRT275277 NUDT4 nudix hydrolase 4 2 2
MIRT298516 SPOPL speckle type BTB/POZ protein like 2 2
MIRT298567 BRWD1 bromodomain and WD repeat domain containing 1 2 2
MIRT302422 CLIP4 CAP-Gly domain containing linker protein family member 4 2 4
MIRT320613 ZNRF2 zinc and ring finger 2 2 2
MIRT320791 PURB purine rich element binding protein B 2 2
MIRT322922 LYN LYN proto-oncogene, Src family tyrosine kinase 2 2
MIRT340714 MZT1 mitotic spindle organizing protein 1 2 2
MIRT347234 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT348559 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT354233 STARD7 StAR related lipid transfer domain containing 7 2 2
MIRT354310 PCNP PEST proteolytic signal containing nuclear protein 2 2
MIRT358523 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2 2
MIRT362352 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2 2
MIRT363825 GOLGA7 golgin A7 2 2
MIRT367234 RPL5 ribosomal protein L5 2 6
MIRT368206 ADIPOR2 adiponectin receptor 2 2 2
MIRT372013 IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 2 4
MIRT374304 ZBTB39 zinc finger and BTB domain containing 39 2 2
MIRT377387 TMCC1 transmembrane and coiled-coil domain family 1 2 2
MIRT379837 USP6NL USP6 N-terminal like 2 8
MIRT392413 RREB1 ras responsive element binding protein 1 2 4
MIRT395591 BMPR2 bone morphogenetic protein receptor type 2 2 2
MIRT400810 CPEB2 cytoplasmic polyadenylation element binding protein 2 2 2
MIRT401743 HLA-DRA major histocompatibility complex, class II, DR alpha 2 2
MIRT408462 MTX3 metaxin 3 2 2
MIRT441521 ZBTB10 zinc finger and BTB domain containing 10 2 2
MIRT442173 AZF1 azoospermia factor 1 2 2
MIRT443086 ABLIM1 actin binding LIM protein 1 2 2
MIRT443391 CHML CHM like, Rab escort protein 2 2 2
MIRT443459 ANP32B acidic nuclear phosphoprotein 32 family member B 2 6
MIRT443653 MRAS muscle RAS oncogene homolog 2 2
MIRT443718 LLPH LLP homolog, long-term synaptic facilitation 2 2
MIRT443963 S1PR2 sphingosine-1-phosphate receptor 2 2 2
MIRT444249 CTNND1 catenin delta 1 2 2
MIRT444795 TMEM251 transmembrane protein 251 2 2
MIRT444943 HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2 2
MIRT445180 ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 2 2
MIRT445334 CWC27 CWC27 spliceosome associated protein homolog 2 2
MIRT445707 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 2
MIRT446048 TPR translocated promoter region, nuclear basket protein 2 2
MIRT446091 ENAH ENAH, actin regulator 2 2
MIRT446236 FZD6 frizzled class receptor 6 2 4
MIRT446543 GOLGA8B golgin A8 family member B 2 2
MIRT446592 FBXO40 F-box protein 40 2 2
MIRT446741 MYEF2 myelin expression factor 2 2 2
MIRT446775 ATAD5 ATPase family, AAA domain containing 5 2 2
MIRT447451 ADM adrenomedullin 2 2
MIRT447801 EPC2 enhancer of polycomb homolog 2 2 2
MIRT448179 IL1RAP interleukin 1 receptor accessory protein 2 4
MIRT448773 GOLGA8A golgin A8 family member A 2 2
MIRT449473 HAT1 histone acetyltransferase 1 2 2
MIRT449635 ELAVL4 ELAV like RNA binding protein 4 2 2
MIRT450237 CDKN2AIP CDKN2A interacting protein 2 2
MIRT450379 TMPRSS15 transmembrane protease, serine 15 2 2
MIRT450506 ALPK3 alpha kinase 3 2 2
MIRT451500 FOPNL FGFR1OP N-terminal like 2 2
MIRT452105 NUCB2 nucleobindin 2 2 2
MIRT456851 ZNF460 zinc finger protein 460 2 2
MIRT463263 ZIC5 Zic family member 5 2 4
MIRT463348 ZFHX3 zinc finger homeobox 3 2 2
MIRT464778 UBE2G1 ubiquitin conjugating enzyme E2 G1 2 2
MIRT467594 SLC7A5 solute carrier family 7 member 5 2 6
MIRT468223 SGK1 serum/glucocorticoid regulated kinase 1 2 2
MIRT468469 SET SET nuclear proto-oncogene 2 4
MIRT469368 REST RE1 silencing transcription factor 2 6
MIRT470526 PPP1CC protein phosphatase 1 catalytic subunit gamma 2 4
MIRT472908 MT1E metallothionein 1E 2 2
MIRT473336 METTL21A methyltransferase like 21A 2 2
MIRT476666 FXR1 FMR1 autosomal homolog 1 2 2
MIRT477145 FAM102B family with sequence similarity 102 member B 2 2
MIRT478928 CPNE3 copine 3 2 2
MIRT479047 COIL coilin 2 8
MIRT481917 ANKRD40 ankyrin repeat domain 40 2 6
MIRT483700 BICD2 BICD cargo adaptor 2 2 8
MIRT483889 TGIF1 TGFB induced factor homeobox 1 2 2
MIRT484733 SF3A1 splicing factor 3a subunit 1 2 2
MIRT485053 THBS1 thrombospondin 1 2 2
MIRT485497 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT485747 CALCR calcitonin receptor 2 2
MIRT486125 MT2A metallothionein 2A 2 2
MIRT494099 DPY19L1 dpy-19 like C-mannosyltransferase 1 2 2
MIRT494103 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT499091 ZDHHC21 zinc finger DHHC-type containing 21 2 4
MIRT501109 SLC5A6 solute carrier family 5 member 6 2 4
MIRT503173 AGO2 argonaute 2, RISC catalytic component 2 4
MIRT504132 RCC1 regulator of chromosome condensation 1 2 6
MIRT504717 DLC1 DLC1 Rho GTPase activating protein 2 6
MIRT505379 TMEM154 transmembrane protein 154 2 4
MIRT505657 SHMT1 serine hydroxymethyltransferase 1 2 4
MIRT505887 RNF219 ring finger protein 219 2 2
MIRT506525 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 6
MIRT507083 GXYLT1 glucoside xylosyltransferase 1 2 6
MIRT507090 GPR180 G protein-coupled receptor 180 2 6
MIRT507174 GAN gigaxonin 2 10
MIRT507940 BTG3 BTG anti-proliferation factor 3 2 6
MIRT508316 RPL18 ribosomal protein L18 2 4
MIRT509452 CAPRIN1 cell cycle associated protein 1 2 4
MIRT509488 LARP1 La ribonucleoprotein domain family member 1 2 10
MIRT509609 GALK2 galactokinase 2 2 8
MIRT510229 PLEKHG3 pleckstrin homology and RhoGEF domain containing G3 2 8
MIRT510607 TPPP tubulin polymerization promoting protein 2 6
MIRT510842 RARB retinoic acid receptor beta 2 6
MIRT510983 PFN2 profilin 2 2 6
MIRT511370 IKZF4 IKAROS family zinc finger 4 2 6
MIRT512481 PPP2CA protein phosphatase 2 catalytic subunit alpha 2 4
MIRT513061 LYPD6 LY6/PLAUR domain containing 6 2 6
MIRT513873 HOXA5 homeobox A5 2 2
MIRT515645 MYBPC1 myosin binding protein C, slow type 2 2
MIRT516649 TRPM6 transient receptor potential cation channel subfamily M member 6 2 2
MIRT516926 OSTF1 osteoclast stimulating factor 1 2 6
MIRT517348 DCAF4L1 DDB1 and CUL4 associated factor 4 like 1 2 6
MIRT519196 NAA38 LSM8 homolog, U6 small nuclear RNA associated 2 6
MIRT520215 WASL Wiskott-Aldrich syndrome like 2 8
MIRT520541 TRA2B transformer 2 beta homolog 2 4
MIRT521613 PSAT1 phosphoserine aminotransferase 1 2 2
MIRT522258 NLK nemo like kinase 2 2
MIRT522809 KPNA3 karyopherin subunit alpha 3 2 6
MIRT522945 IRF2BP2 interferon regulatory factor 2 binding protein 2 2 4
MIRT523347 GUCD1 guanylyl cyclase domain containing 1 2 4
MIRT523375 GSR glutathione-disulfide reductase 2 4
MIRT525158 ZNF329 zinc finger protein 329 2 2
MIRT526066 CCDC81 coiled-coil domain containing 81 2 2
MIRT526164 ELP3 elongator acetyltransferase complex subunit 3 2 2
MIRT526182 HEPH hephaestin 2 2
MIRT526646 TRIM16L tripartite motif containing 16 like 2 2
MIRT527156 SCN9A sodium voltage-gated channel alpha subunit 9 2 4
MIRT527442 COL4A3 collagen type IV alpha 3 chain 2 2
MIRT527685 ZNF552 zinc finger protein 552 2 4
MIRT527751 NANOGNB NANOG neighbor homeobox 2 2
MIRT527788 TMEM44 transmembrane protein 44 2 8
MIRT528462 NXT2 nuclear transport factor 2 like export factor 2 2 4
MIRT528869 RSPH3 radial spoke head 3 homolog 2 2
MIRT529046 ARL9 ADP ribosylation factor like GTPase 9 2 2
MIRT529107 TLL2 tolloid like 2 2 2
MIRT529377 SKP1 S-phase kinase associated protein 1 2 4
MIRT529403 ICK intestinal cell kinase 2 2
MIRT529591 TMEM220 transmembrane protein 220 2 2
MIRT530213 NSUN7 NOP2/Sun RNA methyltransferase family member 7 2 2
MIRT530800 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT530839 MAPK7 mitogen-activated protein kinase 7 2 2
MIRT530859 TTLL5 tubulin tyrosine ligase like 5 2 2
MIRT531433 PAK1 p21 (RAC1) activated kinase 1 2 2
MIRT532311 HAUS3 HAUS augmin like complex subunit 3 2 4
MIRT532501 HOXA13 homeobox A13 2 2
MIRT532601 SIX4 SIX homeobox 4 2 2
MIRT533356 UBE2W ubiquitin conjugating enzyme E2 W 2 4
MIRT534389 SEPT2 septin 2 2 2
MIRT534798 RAB8B RAB8B, member RAS oncogene family 2 2
MIRT536193 MAML3 mastermind like transcriptional coactivator 3 2 2
MIRT536243 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT536534 KCTD10 potassium channel tetramerization domain containing 10 2 2
MIRT536932 HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 2 2
MIRT538628 CCSER2 coiled-coil serine rich protein 2 2 4
MIRT538836 C16orf70 chromosome 16 open reading frame 70 2 2
MIRT538944 BMP2K BMP2 inducible kinase 2 2
MIRT539038 ATXN7L1 ataxin 7 like 1 2 2
MIRT539379 ADSS adenylosuccinate synthase 2 6
MIRT539746 SH3RF2 SH3 domain containing ring finger 2 2 2
MIRT539879 RPL32 ribosomal protein L32 2 2
MIRT539956 CCT4 chaperonin containing TCP1 subunit 4 2 2
MIRT540458 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT541611 ASB11 ankyrin repeat and SOCS box containing 11 2 2
MIRT543034 C15orf48 chromosome 15 open reading frame 48 2 2
MIRT544838 PLA2G16 phospholipase A2 group XVI 2 2
MIRT546177 TRIAP1 TP53 regulated inhibitor of apoptosis 1 2 2
MIRT546320 TM9SF3 transmembrane 9 superfamily member 3 2 4
MIRT546897 PTPRK protein tyrosine phosphatase, receptor type K 2 2
MIRT546950 SFTPA1 surfactant protein A1 2 2
MIRT547166 PDZD8 PDZ domain containing 8 2 2
MIRT547323 NPTN neuroplastin 2 2
MIRT547359 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT547562 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT548082 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT548218 FKBP1A FK506 binding protein 1A 2 2
MIRT548768 CNN3 calponin 3 2 2
MIRT548925 CDK6 cyclin dependent kinase 6 2 2
MIRT548954 CDC27 cell division cycle 27 2 2
MIRT549696 TLE3 transducin like enhancer of split 3 2 4
MIRT549734 NUP37 nucleoporin 37 2 2
MIRT549863 MCM4 minichromosome maintenance complex component 4 2 2
MIRT551070 MKLN1 muskelin 1 2 2
MIRT551194 EPB41L3 erythrocyte membrane protein band 4.1 like 3 2 2
MIRT552113 EMC7 ER membrane protein complex subunit 7 2 2
MIRT552236 SART3 squamous cell carcinoma antigen recognized by T-cells 3 2 2
MIRT552287 CBY1 chibby family member 1, beta catenin antagonist 2 4
MIRT552468 ZNF280B zinc finger protein 280B 2 2
MIRT553628 TJP1 tight junction protein 1 2 2
MIRT555507 PNISR PNN interacting serine and arginine rich protein 2 2
MIRT556953 IGF1R insulin like growth factor 1 receptor 2 4
MIRT557203 HNRNPU heterogeneous nuclear ribonucleoprotein U 2 4
MIRT557538 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT557603 GNPTAB N-acetylglucosamine-1-phosphate transferase alpha and beta subunits 2 2
MIRT558233 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 2
MIRT558261 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT558336 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT558875 CCT6A chaperonin containing TCP1 subunit 6A 2 2
MIRT559684 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT559986 RPL24 ribosomal protein L24 2 2
MIRT561051 SKP2 S-phase kinase associated protein 2 2 2
MIRT561783 PAXBP1 PAX3 and PAX7 binding protein 1 2 2
MIRT561833 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT562588 CBX2 chromobox 2 2 2
MIRT562956 TNIP2 TNFAIP3 interacting protein 2 2 2
MIRT563047 NBPF12 NBPF member 12 2 2
MIRT563157 NOLC1 nucleolar and coiled-body phosphoprotein 1 2 2
MIRT563213 ZNF813 zinc finger protein 813 2 2
MIRT563436 SLC3A2 solute carrier family 3 member 2 2 2
MIRT563927 STAT2 signal transducer and activator of transcription 2 2 2
MIRT564149 GTF2E1 general transcription factor IIE subunit 1 2 2
MIRT564204 ABT1 activator of basal transcription 1 2 2
MIRT564214 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT564637 ZNF562 zinc finger protein 562 2 4
MIRT564932 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 2
MIRT565587 SLC6A8 solute carrier family 6 member 8 2 2
MIRT565667 SIX1 SIX homeobox 1 2 2
MIRT566233 PTMA prothymosin, alpha 2 2
MIRT566237 PTCH1 patched 1 2 2
MIRT566454 PHAX phosphorylated adaptor for RNA export 2 4
MIRT566949 LEPROT leptin receptor overlapping transcript 2 2
MIRT567323 HMGB2 high mobility group box 2 2 2
MIRT568381 ATP13A3 ATPase 13A3 2 2
MIRT568427 ATF7IP activating transcription factor 7 interacting protein 2 4
MIRT571579 USP15 ubiquitin specific peptidase 15 2 2
MIRT572335 CACNA1A calcium voltage-gated channel subunit alpha1 A 2 2
MIRT573391 GGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 2 2
MIRT573574 RANBP1 RAN binding protein 1 2 2
MIRT574388 UBE2N ubiquitin conjugating enzyme E2 N 2 2
MIRT576611 Ccdc117 coiled-coil domain containing 117 2 2
MIRT608962 GIMAP1 GTPase, IMAP family member 1 2 4
MIRT609962 ATF7IP2 activating transcription factor 7 interacting protein 2 2 2
MIRT611714 GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 2 2
MIRT613603 SCN1A sodium voltage-gated channel alpha subunit 1 2 2
MIRT614014 PAOX polyamine oxidase 2 2
MIRT614159 GNA14 G protein subunit alpha 14 2 2
MIRT614181 FAM53B family with sequence similarity 53 member B 2 2
MIRT614544 EIF4G3 eukaryotic translation initiation factor 4 gamma 3 2 2
MIRT615284 FGF5 fibroblast growth factor 5 2 2
MIRT615831 PCSK7 proprotein convertase subtilisin/kexin type 7 2 2
MIRT618541 SEMA5A semaphorin 5A 2 2
MIRT619136 MCOLN3 mucolipin 3 2 2
MIRT619455 NUP214 nucleoporin 214 2 2
MIRT620038 ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 2 2
MIRT620243 CCDC65 coiled-coil domain containing 65 2 2
MIRT620369 CD55 CD55 molecule (Cromer blood group) 2 2
MIRT620474 CERS6 ceramide synthase 6 2 2
MIRT620881 KCTD7 potassium channel tetramerization domain containing 7 2 2
MIRT621948 STYX serine/threonine/tyrosine interacting protein 2 2
MIRT622156 SNTG1 syntrophin gamma 1 2 2
MIRT622312 SETD5 SET domain containing 5 2 2
MIRT622486 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT623190 NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 2 2
MIRT623650 HS3ST5 heparan sulfate-glucosamine 3-sulfotransferase 5 2 2
MIRT623655 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT624403 CCDC80 coiled-coil domain containing 80 2 4
MIRT624489 CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 2 2
MIRT624694 AR androgen receptor 2 2
MIRT625011 PAK4 p21 (RAC1) activated kinase 4 2 2
MIRT625792 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha 2 2
MIRT625987 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta 2 2
MIRT626122 MRRF mitochondrial ribosome recycling factor 2 2
MIRT626394 ZMYM6 zinc finger MYM-type containing 6 2 2
MIRT626560 NAGS N-acetylglutamate synthase 2 2
MIRT626568 DRAM2 DNA damage regulated autophagy modulator 2 2 2
MIRT626647 ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 2 2
MIRT626956 PRDM2 PR/SET domain 2 2 2
MIRT627868 PARVB parvin beta 2 2
MIRT628071 KCNJ13 potassium voltage-gated channel subfamily J member 13 2 2
MIRT628198 GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 2 2
MIRT630547 GJB7 gap junction protein beta 7 2 2
MIRT633570 LAMP2 lysosomal associated membrane protein 2 2 2
MIRT635535 ELMOD2 ELMO domain containing 2 2 2
MIRT636219 SNAI2 snail family transcriptional repressor 2 2 2
MIRT636614 CLIC5 chloride intracellular channel 5 2 2
MIRT640754 ZBTB26 zinc finger and BTB domain containing 26 2 2
MIRT640996 PROK2 prokineticin 2 2 2
MIRT641143 ZBTB33 zinc finger and BTB domain containing 33 2 2
MIRT642288 ZNF99 zinc finger protein 99 2 2
MIRT643506 ZNF28 zinc finger protein 28 2 2
MIRT644027 ZNF792 zinc finger protein 792 2 2
MIRT644073 PARG poly(ADP-ribose) glycohydrolase 2 2
MIRT644598 SPOP speckle type BTB/POZ protein 2 2
MIRT644631 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT644955 IFNB1 interferon beta 1 2 2
MIRT646357 CPT1B carnitine palmitoyltransferase 1B 2 2
MIRT647624 IGSF9B immunoglobulin superfamily member 9B 2 2
MIRT649089 FBXO25 F-box protein 25 2 4
MIRT649382 NEDD1 neural precursor cell expressed, developmentally down-regulated 1 2 2
MIRT651176 ZNF319 zinc finger protein 319 2 2
MIRT652305 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT652393 TMEM55A phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 2 2
MIRT652815 TBL2 transducin beta like 2 2 2
MIRT653111 SRSF1 serine and arginine rich splicing factor 1 2 2
MIRT653145 SRPK2 SRSF protein kinase 2 2 2
MIRT653815 SIN3A SIN3 transcription regulator family member A 2 2
MIRT653947 SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 2 2
MIRT655157 PHF21A PHD finger protein 21A 2 2
MIRT655317 PDCD11 programmed cell death 11 2 2
MIRT656937 KIAA1456 KIAA1456 2 2
MIRT657000 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT657557 GSK3B glycogen synthase kinase 3 beta 2 2
MIRT657692 GPR135 G protein-coupled receptor 135 2 2
MIRT658251 FAXC failed axon connections homolog 2 2
MIRT658717 ELOVL4 ELOVL fatty acid elongase 4 2 2
MIRT659421 COL4A4 collagen type IV alpha 4 chain 2 2
MIRT659488 CLDN1 claudin 1 2 2
MIRT659534 CHD9 chromodomain helicase DNA binding protein 9 2 2
MIRT659574 CEP85L centrosomal protein 85 like 2 2
MIRT660570 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT661595 BMPR1B bone morphogenetic protein receptor type 1B 2 2
MIRT661844 ZNF587B zinc finger protein 587B 2 2
MIRT663397 COA4 cytochrome c oxidase assembly factor 4 homolog 2 2
MIRT664409 TNFRSF21 TNF receptor superfamily member 21 2 2
MIRT664804 GALC galactosylceramidase 2 2
MIRT664834 GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 2 2
MIRT666146 SP4 Sp4 transcription factor 2 2
MIRT666779 PTGES3L prostaglandin E synthase 3 like 2 2
MIRT667105 SLC25A2 solute carrier family 25 member 2 2 2
MIRT667115 OLA1 Obg like ATPase 1 2 2
MIRT667504 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT668011 HCFC2 host cell factor C2 2 2
MIRT672876 TTC28 tetratricopeptide repeat domain 28 2 2
MIRT682598 CPA4 carboxypeptidase A4 2 2
MIRT683340 ZNF581 zinc finger protein 581 2 2
MIRT683581 CARD8 caspase recruitment domain family member 8 2 2
MIRT683691 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT683712 EXOSC6 exosome component 6 2 4
MIRT684560 ZNF708 zinc finger protein 708 2 2
MIRT685425 ACAD8 acyl-CoA dehydrogenase family member 8 2 2
MIRT685509 LSG1 large 60S subunit nuclear export GTPase 1 2 2
MIRT686052 SLC5A5 solute carrier family 5 member 5 2 2
MIRT686140 B4GALT7 beta-1,4-galactosyltransferase 7 2 2
MIRT686425 TVP23C trans-golgi network vesicle protein 23 homolog C 2 2
MIRT687716 KLF2 Kruppel like factor 2 2 2
MIRT687727 KIAA1467 family with sequence similarity 234 member B 2 2
MIRT688183 FRRS1 ferric chelate reductase 1 2 2
MIRT688306 FAM208A family with sequence similarity 208 member A 2 2
MIRT688420 DUSP2 dual specificity phosphatase 2 2 2
MIRT688491 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT688725 CPS1 carbamoyl-phosphate synthase 1 2 2
MIRT689208 ZNF574 zinc finger protein 574 2 2
MIRT690340 DHX36 DEAH-box helicase 36 2 2
MIRT690516 ZNF845 zinc finger protein 845 2 2
MIRT690614 DCTN3 dynactin subunit 3 2 2
MIRT691051 RDH13 retinol dehydrogenase 13 2 2
MIRT691265 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT692171 RNF207 ring finger protein 207 2 2
MIRT692728 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT693384 ZNF528 zinc finger protein 528 2 2
MIRT694449 GSG2 histone H3 associated protein kinase 2 2
MIRT694485 LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 2 2
MIRT695650 NUP205 nucleoporin 205 2 2
MIRT695803 SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 2 2
MIRT696128 GLP2R glucagon like peptide 2 receptor 2 2
MIRT696694 APOC3 apolipoprotein C3 2 2
MIRT696888 SAMD15 sterile alpha motif domain containing 15 2 2
MIRT697790 UBXN7 UBX domain protein 7 2 2
MIRT698144 TNPO3 transportin 3 2 2
MIRT698363 TMEM127 transmembrane protein 127 2 2
MIRT698489 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT699121 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT699849 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT701321 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT701386 NOA1 nitric oxide associated 1 2 2
MIRT701391 NLRC3 NLR family CARD domain containing 3 2 2
MIRT701954 MITF melanogenesis associated transcription factor 2 2
MIRT702167 MAP1LC3B microtubule associated protein 1 light chain 3 beta 2 2
MIRT702782 IFNLR1 interferon lambda receptor 1 2 2
MIRT703466 FOXJ3 forkhead box J3 2 2
MIRT703968 EMP2 epithelial membrane protein 2 2 2
MIRT703973 EMC10 ER membrane protein complex subunit 10 2 2
MIRT704350 DCAF16 DDB1 and CUL4 associated factor 16 2 2
MIRT704603 CLN8 CLN8, transmembrane ER and ERGIC protein 2 2
MIRT705272 BAHD1 bromo adjacent homology domain containing 1 2 2
MIRT707156 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT707271 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT707461 PPFIBP1 PPFIA binding protein 1 2 2
MIRT707505 AXL AXL receptor tyrosine kinase 2 2
MIRT707705 FAM118A family with sequence similarity 118 member A 2 2
MIRT707722 CDC6 cell division cycle 6 2 2
MIRT708018 TSPAN1 tetraspanin 1 2 2
MIRT708071 LIX1L limb and CNS expressed 1 like 2 2
MIRT708139 GK5 glycerol kinase 5 (putative) 2 2
MIRT710550 NR4A2 nuclear receptor subfamily 4 group A member 2 2 2
MIRT713228 GPR75 G protein-coupled receptor 75 2 2
MIRT713273 SPRTN SprT-like N-terminal domain 2 2
MIRT715622 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT716477 SESTD1 SEC14 and spectrin domain containing 1 2 2
MIRT716492 ZNF394 zinc finger protein 394 2 2
MIRT717715 NCKAP1 NCK associated protein 1 2 2
MIRT718046 ANAPC1 anaphase promoting complex subunit 1 2 2
MIRT719400 SLC15A4 solute carrier family 15 member 4 2 2
MIRT719899 PTGIS prostaglandin I2 synthase 2 2
MIRT720781 MSANTD3-TMEFF1 MSANTD3-TMEFF1 readthrough 2 2
MIRT722063 TMEFF1 transmembrane protein with EGF like and two follistatin like domains 1 2 2
MIRT723234 FAM91A1 family with sequence similarity 91 member A1 2 2
MIRT723768 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT724057 FAM84A family with sequence similarity 84 member A 2 2
MIRT725194 SDAD1 SDA1 domain containing 1 2 2
MIRT735687 IL6ST interleukin 6 signal transducer 2 0
MIRT735689 ACVR1C activin A receptor type 1C 2 0
MIRT736080 SPOCK1 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 1 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-548c-3p Vorinostat (SAHA) approved 5311 Microarray A549 human non-small cell lung cancer cells 19513533 2009 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-548c Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-548c-3p Sorafenib 216239 NSC747971 approved resistant High Hepatocellular Carcinoma cell line (HepG2, Hep-394, Hep-SWX, Huh-7)
hsa-miR-548c-3p Mitoxantrone 4212 NSC279836 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-548c-3p Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer tissue
hsa-miR-548c-3p Fluorouracil 3385 NSC19893 approved sensitive High Gastric Cancer tissue
hsa-miR-548c-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-548c-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-548c-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-548c-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-548c-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-548c-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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