miRTarBase - #MIRT106310


—
pre-miRNA Information
pre-miRNA hsa-mir-4524a   
Genomic Coordinates chr17: 69099564 - 69099632
Description Homo sapiens miR-4524a stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4524a-5p
Sequence 6| AUAGCAGCAUGAACCUGUCUCA |27
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1322445998 8 dbSNP
rs1350790266 13 dbSNP
rs1263495678 21 dbSNP
Putative Targets

Gene Information
Gene Symbol ZFHX4   
Synonyms ZFH4, ZHF4
Description zinc finger homeobox 4
Transcript NM_024721   
Expression
Putative miRNA Targets on ZFHX4
3'UTR of ZFHX4
(miRNA target sites are highlighted)		 
>ZFHX4|NM_024721|3'UTR
   1 GAGTGAAGACAGGATCCCGTGCTTAAAAAAATAAAAAATAAAAAAATAAAAAAAAAATAAGACTTTAACTGCAGTTCCAA
  81 AGCTTCTCTAACCCAAAAATTACAGTACCAAATGATTGACTCAGGATTGTTTTTCCCATATTGATATGCTGGCAATATAG
 161 GATGGTATGTAATGGACAGAACTGATGCAGATGGTTGAATGCGCTTGTACTATATGCTAAAATATGGAAAAGGAAAAAAA
 241 AATCTCACAAGTTCTTTTGGAACTTGTTTCAAGCCAAAAACTCTCAAGAAAGCAAATTGCACCTCAGCTGGATTGATTTC
 321 CAAATGCTAGCATGTACTGTATGGGAGGATGATCCAGATGTTTCAAAGAGAATTTCTCTTAGTTTAGTTAGGTGTAATTC
 401 AGTAGCTTTAAATTCTCAGGTCAGAACATAACATTTCTCATTTGTTAAAAGCAGCAAGAAGCCTGGTAAAACTGTGACTT
 481 TTCCCCAAACGTCAATCTTTATTAGAAAGCATTTTCTAGGTGTGTTTAGTGTACAAAGAGACTTTATAACCCTTACTGGA
 561 CAACACACAGATCCTTGAGCTCACGCTGCAGGATAGTACAGTTTTACCGCAGAGGGAATCTGGAACAGTGGAATCATGTG
 641 TCTGCCCTGTGTATTGCAGTTTGTATTGCCACAAGCTATATTTATACCAGTGTCACCCTTTTCTTGTAGAATATACTAAT
 721 AATCTGTGCCAACTCTACCTTCTCACTTTTACCTCTGACGTCATTCTTTTTTTCTGAAAGAGGTAATAATTCTAGTTTTG
 801 ATAGACTCTGAGGATTATGTGAACAGGACATTTTTCATTTGTGAATTTAATGCTATACTGTCAAGGTACTTGCTTGTGTC
 881 TGAACTCTAGTGCACTTATGATTTTGTAGACCATGTGAAATTTAATAAGATACCTTTTTTTTCCTTTCTTTGTGTGTAGT
 961 GCAGCAACAGTTTGGTCTGCATTTGTTAGAAGTTTAACTCCTAACAACCCAAAGACCTATTTAACAATTGGTGCATAAAT
1041 GAAAGTAGTACTGTATACTTGAAACTGTTTAAGTACAAGTTGAACAAAAATTATGAAAAGGTATATTTGCTTCTCGGGAA
1121 AGCAAAGAAGCTGCTTTAAAAAATAAAAAGGGGACTAAAAATTTGTTTTGTATAAAGAGGTTAGCCCTGCGCACGTAGGA
1201 CTGAATTCAGTGATATCCCTATACACTGCCATTTAGTGGATAGGTTATTGTACTTCCATTCATACTCTGGGCACTTGTGT
1281 TGTATTGTTCTGTTACATACTTTTTTTAACCTGTTTTGTTTTATCATATATGCATTAAAAGTATTATCTTTATCAACATT
1361 TGCTGCTACTGTGTTAACATTTTTGTTTTGCTTGCCATGAATTTCAACTTCCACCACCCAGTGAATTGATTTATAAATTG
1441 CTATGCTTTGCTGTTTTTCTGTTGCTGTGGAACTTAAAGAATGTGAAAGCTGTCAAAGGGTATTTTACGAATCACTTTTG
1521 TGTTTGATATAGTAAAACAATGTGATTCATTCCAAAGTAACAGAAGGTTATTTGTAAGAAAGTTAAAGGCTTGTGAACAA
1601 AGAAAGCTAAGCTGTTGTACATATTTGTAGTTGGCTGTGCATGGTACAAATTTATTAATATGAAGAAATGCAAAATGTAT
1681 TGCTTTTGATATTTCTCTTCCGAGATGAACAAGTAGCATGTAATGCAACTGTTTGACAGTTTAACTCAAGTCATGCTTCA
1761 AACTGTTTTAATGATCAAATCAAGACACATTTCATTTTACATTTTATTATTGTACAGTTTTTGTTTCGGATGATGATCAC
1841 AGCAATCTTTATTCTATACATTTTATGTGAACTTTTTTAATGTCTTTAATTTGGATTTTTTTTTTTTTTAGTATTTTAAC
1921 ATTTATTTTAATCCTGAAGACACTTTTTTGATTGTGTTTCGTAAGAGACAACATGGCCTCCTAAGGTGCAATCCTGCCGC
2001 TATAGTGAGCTAATGTCCTGAATCCAAAGGCTTCAGAAAATTGCTTTTGCCTTTTTCATGAATGTTAAGCAGCAGCATTG
2081 TGAGATCGATCTGTCCTGGCAGTTAACACGATGTGCAACAGTGTGTTAGCATGGAACAGAACGCTTTTCACAAAACAAAG
2161 GACTGTTTTACAAATGATTATTCCGACAGTGTGTCGACATAAACTTTTACAACTGCACAGCAGCCAAAAAAAGAAAAAAA
2241 AAAGAAAAAAAACTTTAACTGGATGGACGTTGTTAGGGTGAGAAATAAAAGGACAGCCTCCAAAGGTTGAGAATGAGAAT
2321 TGTTTTTTCCTGGATATCAAAGGGATTATCACAGCGCAATCATTGTCTACACAACATGTACTCTCAACGCCTGGGTTACA
2401 TAGGAAATGCACCCTGAGGTTTTAATAAAAGCCCCTATGGCTATAACTTTAAATAAACTAAACCAAAAATGTTATTGATG
2481 TTTTATATATAGAGAGTAGTCTCATTAGTTTTTGTTACTGTAATGTTTGAAGTCTCAAATGCACCGTATTACGGTAAATA
2561 ACATGGTTTTGAAAACTTTTTTTTATTTTGTCACAGACCTGTTGTCATAGTTGAAATGATGTTTATTGTAGATGGTATTT
2641 GAACTTATTCTTCTGGAAATAGTTCATCAAGTATGTTTGTTGCTCATTGTGATACATTAAAAACTGTATCTACATATTTA
2721 AAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acucUGUCCAAGUACGACGAUa 5'
              |||  ||  |||||||| 
Target 5' atcaACA--TT--TGCTGCTAc 3'
 1352 - 1369 150.00 -9.30
2 
miRNA  3' acucugUCCA----AGUACGACGAUa 5'
                ||||    || ||| |||| 
Target 5' ctcctaAGGTGCAATCCTGCCGCTAt 3'
 1978 - 2003 126.00 -10.50
3 
miRNA  3' acUCUGUCCAAGUACGACGAUa 5'
            ||| || |  | ||||:|: 
Target 5' aaAGAAAGCT--AAGCTGTTGt 3'
 1599 - 1618 124.00 -10.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN9680617 2 COSMIC
COSN30661755 15 COSMIC
COSN30517881 17 COSMIC
COSN30473150 19 COSMIC
COSN31527053 45 COSMIC
COSN30110861 55 COSMIC
COSN1368382 58 COSMIC
COSN20105588 58 COSMIC
COSN19456232 83 COSMIC
COSN30045402 99 COSMIC
COSN21107797 118 COSMIC
COSN31598137 141 COSMIC
COSN27910130 152 COSMIC
COSN31480302 162 COSMIC
COSN31530898 167 COSMIC
COSN31562676 183 COSMIC
COSN23843100 197 COSMIC
COSN9269389 208 COSMIC
COSN31592052 244 COSMIC
COSN31485537 255 COSMIC
COSN31519601 278 COSMIC
COSN31561974 359 COSMIC
COSN21068444 365 COSMIC
COSN31490380 494 COSMIC
COSN15955319 506 COSMIC
COSN31522377 521 COSMIC
COSN28438701 586 COSMIC
COSN23076969 597 COSMIC
COSN31596663 598 COSMIC
COSN31518603 669 COSMIC
COSN31607563 736 COSMIC
COSN28639610 834 COSMIC
COSN31569791 937 COSMIC
COSN31529809 949 COSMIC
COSN31548727 949 COSMIC
COSN26566989 971 COSMIC
COSN27699342 981 COSMIC
COSN31548294 1019 COSMIC
COSN8519459 1096 COSMIC
COSN22272777 1117 COSMIC
COSN28677943 1153 COSMIC
COSN31551713 1162 COSMIC
COSN31486170 1164 COSMIC
COSN30444448 1237 COSMIC
COSN19611447 1242 COSMIC
COSN24302656 1356 COSMIC
COSN31572110 1375 COSMIC
COSN8519460 1396 COSMIC
COSN8519461 1397 COSMIC
COSN8519462 1401 COSMIC
COSN31531341 1403 COSMIC
COSN6363618 1419 COSMIC
COSN31588238 1432 COSMIC
COSN8101971 1509 COSMIC
COSN17309831 1514 COSMIC
COSN31569797 1544 COSMIC
COSN24466741 1558 COSMIC
COSN31607406 1653 COSMIC
COSN23570849 1702 COSMIC
COSN28637487 1764 COSMIC
COSN14972436 1833 COSMIC
COSN31530121 1843 COSMIC
COSN24294976 1855 COSMIC
COSN32061517 1910 COSMIC
COSN28745448 1937 COSMIC
COSN8519463 1937 COSMIC
COSN31578900 1948 COSMIC
COSN31589552 2000 COSMIC
COSN27763717 2002 COSMIC
COSN8519464 2119 COSMIC
COSN26504578 2122 COSMIC
COSN26465425 2234 COSMIC
COSN31559469 2235 COSMIC
COSN20418683 2244 COSMIC
COSN17666287 2245 COSMIC
COSN20105593 2253 COSMIC
COSN26469388 2255 COSMIC
COSN31607054 2256 COSMIC
COSN31532728 2264 COSMIC
COSN26574806 2273 COSMIC
COSN28411550 2357 COSMIC
COSN23452369 2390 COSMIC
COSN31585677 2412 COSMIC
COSN5238591 2421 COSMIC
COSN27157436 2443 COSMIC
COSN31591325 2495 COSMIC
COSN32069355 2553 COSMIC
COSN31583004 2577 COSMIC
COSN31597169 2585 COSMIC
COSN31526824 2634 COSMIC
COSN31571696 2647 COSMIC
COSN31591352 2678 COSMIC
COSN18968090 2682 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1367401495 2 dbSNP
rs1163628586 4 dbSNP
rs542039768 6 dbSNP
rs756884261 13 dbSNP
rs377073632 15 dbSNP
rs755255231 19 dbSNP
rs781638674 20 dbSNP
rs1262087573 24 dbSNP
rs1203778723 25 dbSNP
rs1261399346 25 dbSNP
rs1356727590 28 dbSNP
rs1221072498 32 dbSNP
rs1269535232 33 dbSNP
rs949224880 40 dbSNP
rs1222460252 42 dbSNP
rs1357350680 44 dbSNP
rs1363993727 45 dbSNP
rs1037344400 47 dbSNP
rs3830275 48 dbSNP
rs771325758 48 dbSNP
rs777118177 48 dbSNP
rs957096915 48 dbSNP
rs1491348235 49 dbSNP
rs200572308 49 dbSNP
rs748549046 50 dbSNP
rs1438647494 53 dbSNP
rs1048390617 54 dbSNP
rs867265458 55 dbSNP
rs949907565 56 dbSNP
rs1046016645 57 dbSNP
rs1190630190 58 dbSNP
rs768313922 70 dbSNP
rs927197439 72 dbSNP
rs937253751 83 dbSNP
rs1317633459 109 dbSNP
rs1055106053 114 dbSNP
rs1481608539 127 dbSNP
rs1270118495 137 dbSNP
rs560378518 142 dbSNP
rs527630143 143 dbSNP
rs1259246595 153 dbSNP
rs1275138836 156 dbSNP
rs1196481465 161 dbSNP
rs1047797667 162 dbSNP
rs1338943011 163 dbSNP
rs1249810074 165 dbSNP
rs868699275 175 dbSNP
rs886561026 179 dbSNP
rs150375735 181 dbSNP
rs1325405618 188 dbSNP
rs1283766092 190 dbSNP
rs1019540467 193 dbSNP
rs1006941504 194 dbSNP
rs1329294030 198 dbSNP
rs964964097 201 dbSNP
rs1391433482 202 dbSNP
rs78152837 203 dbSNP
rs542187565 204 dbSNP
rs1470788560 206 dbSNP
rs1010431413 209 dbSNP
rs957022404 211 dbSNP
rs1477300015 212 dbSNP
rs988471925 215 dbSNP
rs1183222809 216 dbSNP
rs138036812 222 dbSNP
rs1180637782 224 dbSNP
rs979474460 226 dbSNP
rs971561260 227 dbSNP
rs1409227426 229 dbSNP
rs924986105 234 dbSNP
rs959088027 234 dbSNP
rs981268368 240 dbSNP
rs1342659841 248 dbSNP
rs1165318397 253 dbSNP
rs116113052 263 dbSNP
rs1334652562 279 dbSNP
rs1328688878 285 dbSNP
rs1454195105 294 dbSNP
rs1456297749 303 dbSNP
rs937181634 318 dbSNP
rs751502767 324 dbSNP
rs919872721 328 dbSNP
rs1374127608 334 dbSNP
rs1422342435 348 dbSNP
rs930626536 349 dbSNP
rs1179852596 353 dbSNP
rs1048194175 358 dbSNP
rs886493324 359 dbSNP
rs1470133486 361 dbSNP
rs1378487553 366 dbSNP
rs1390965881 368 dbSNP
rs1304967344 390 dbSNP
rs944802178 391 dbSNP
rs774310916 392 dbSNP
rs184637621 395 dbSNP
rs1242724829 401 dbSNP
rs1202064249 403 dbSNP
rs917702870 459 dbSNP
rs996330203 462 dbSNP
rs1033217324 471 dbSNP
rs114819665 478 dbSNP
rs972633271 484 dbSNP
rs555187211 491 dbSNP
rs1247578675 492 dbSNP
rs372496598 501 dbSNP
rs1382940267 506 dbSNP
rs1313901888 510 dbSNP
rs1020383681 512 dbSNP
rs971146783 519 dbSNP
rs931251755 524 dbSNP
rs1048844470 530 dbSNP
rs1319397305 539 dbSNP
rs868386547 556 dbSNP
rs981580443 559 dbSNP
rs1034131597 567 dbSNP
rs1480592972 568 dbSNP
rs189493353 569 dbSNP
rs1384749115 584 dbSNP
rs973939657 585 dbSNP
rs534227100 586 dbSNP
rs919800682 590 dbSNP
rs1193658125 591 dbSNP
rs1487900460 592 dbSNP
rs1283763538 593 dbSNP
rs558787293 595 dbSNP
rs1010818407 597 dbSNP
rs1226194384 598 dbSNP
rs752584363 600 dbSNP
rs1271089295 601 dbSNP
rs1430417861 606 dbSNP
rs1338964977 609 dbSNP
rs531366346 610 dbSNP
rs983444980 611 dbSNP
rs1416866810 612 dbSNP
rs576449437 617 dbSNP
rs1364965898 623 dbSNP
rs1421894791 625 dbSNP
rs1411817130 636 dbSNP
rs944750085 648 dbSNP
rs1167599668 655 dbSNP
rs1477360888 663 dbSNP
rs180681967 666 dbSNP
rs1201502069 671 dbSNP
rs1490495639 679 dbSNP
rs900629943 688 dbSNP
rs1245568156 690 dbSNP
rs1218772399 691 dbSNP
rs755916804 693 dbSNP
rs1273238426 695 dbSNP
rs879523543 718 dbSNP
rs1461432903 738 dbSNP
rs1217697753 751 dbSNP
rs1306206449 754 dbSNP
rs1054555902 760 dbSNP
rs893359314 761 dbSNP
rs1345458231 764 dbSNP
rs1292963058 767 dbSNP
rs1010923134 769 dbSNP
rs1291816671 775 dbSNP
rs1034625597 777 dbSNP
rs1020557768 784 dbSNP
rs1169993411 785 dbSNP
rs1216622472 787 dbSNP
rs1464323661 794 dbSNP
rs1296753960 801 dbSNP
rs1421126571 807 dbSNP
rs1178343577 808 dbSNP
rs906849974 812 dbSNP
rs1480696331 821 dbSNP
rs1424414319 825 dbSNP
rs1189450623 826 dbSNP
rs1481318530 828 dbSNP
rs1002574827 829 dbSNP
rs1197544128 836 dbSNP
rs1307373228 842 dbSNP
rs1034095958 854 dbSNP
rs974274114 854 dbSNP
rs1312020899 856 dbSNP
rs1299795003 857 dbSNP
rs555868019 858 dbSNP
rs1203068073 861 dbSNP
rs1226036072 867 dbSNP
rs1374142839 869 dbSNP
rs574514084 871 dbSNP
rs1444768554 873 dbSNP
rs1408606155 887 dbSNP
rs1338412887 888 dbSNP
rs541556648 889 dbSNP
rs958444940 900 dbSNP
rs1486394288 901 dbSNP
rs1211139419 908 dbSNP
rs1173859594 911 dbSNP
rs1420807702 912 dbSNP
rs777478441 913 dbSNP
rs753491050 914 dbSNP
rs1482075207 927 dbSNP
rs918437483 932 dbSNP
rs1177491167 933 dbSNP
rs185095158 934 dbSNP
rs1203961004 935 dbSNP
rs12155655 935 dbSNP
rs1218477408 935 dbSNP
rs1187987593 938 dbSNP
rs1026834688 940 dbSNP
rs951255476 943 dbSNP
rs1427812780 944 dbSNP
rs1166689720 945 dbSNP
rs1396947650 949 dbSNP
rs745413121 953 dbSNP
rs1401145787 960 dbSNP
rs1300879438 962 dbSNP
rs1455238575 963 dbSNP
rs984035906 969 dbSNP
rs911165518 975 dbSNP
rs1417296982 979 dbSNP
rs1386619752 981 dbSNP
rs558870589 996 dbSNP
rs983089420 1009 dbSNP
rs757497032 1030 dbSNP
rs912511735 1039 dbSNP
rs1357581831 1059 dbSNP
rs1188685573 1066 dbSNP
rs966432798 1070 dbSNP
rs976148956 1071 dbSNP
rs921981769 1073 dbSNP
rs901226546 1074 dbSNP
rs1361671282 1077 dbSNP
rs946166656 1079 dbSNP
rs1244257120 1084 dbSNP
rs1042255485 1086 dbSNP
rs904672805 1088 dbSNP
rs1383672633 1094 dbSNP
rs932077093 1101 dbSNP
rs1361747035 1103 dbSNP
rs1398147773 1104 dbSNP
rs1366822682 1108 dbSNP
rs1054528671 1109 dbSNP
rs1163681718 1110 dbSNP
rs879413322 1116 dbSNP
rs1306345684 1117 dbSNP
rs1172141293 1123 dbSNP
rs189423019 1130 dbSNP
rs1429462952 1134 dbSNP
rs527442327 1137 dbSNP
rs571948124 1140 dbSNP
rs1042353775 1142 dbSNP
rs1192043342 1150 dbSNP
rs1490986351 1157 dbSNP
rs1279011822 1161 dbSNP
rs1269635778 1162 dbSNP
rs907488174 1164 dbSNP
rs371118918 1166 dbSNP
rs1217537892 1173 dbSNP
rs1228507364 1175 dbSNP
rs781767334 1182 dbSNP
rs748594607 1190 dbSNP
rs1055475875 1191 dbSNP
rs532714982 1192 dbSNP
rs995275826 1195 dbSNP
rs1385704705 1196 dbSNP
rs1026760727 1204 dbSNP
rs531484960 1206 dbSNP
rs1465820084 1210 dbSNP
rs1454664744 1219 dbSNP
rs1423284151 1226 dbSNP
rs1173028198 1227 dbSNP
rs972525327 1247 dbSNP
rs1025837136 1251 dbSNP
rs550989200 1258 dbSNP
rs1449924098 1262 dbSNP
rs951278998 1269 dbSNP
rs1252835321 1273 dbSNP
rs563066841 1280 dbSNP
rs1004083978 1284 dbSNP
rs1257138410 1288 dbSNP
rs1216608961 1294 dbSNP
rs1325477479 1295 dbSNP
rs548016205 1296 dbSNP
rs113946042 1297 dbSNP
rs976022814 1299 dbSNP
rs1308531535 1301 dbSNP
rs1446996305 1304 dbSNP
rs1160169825 1305 dbSNP
rs963932718 1308 dbSNP
rs1344961061 1314 dbSNP
rs200940625 1317 dbSNP
rs371086829 1317 dbSNP
rs202064475 1318 dbSNP
rs16939381 1319 dbSNP
rs1365551859 1323 dbSNP
rs1440853564 1329 dbSNP
rs1439277451 1330 dbSNP
rs1236552945 1333 dbSNP
rs1205870929 1335 dbSNP
rs749525302 1338 dbSNP
rs926066315 1342 dbSNP
rs1199745888 1355 dbSNP
rs1342318276 1358 dbSNP
rs953403004 1371 dbSNP
rs1225095036 1372 dbSNP
rs936182336 1374 dbSNP
rs1375583250 1386 dbSNP
rs1316117596 1391 dbSNP
rs1206524361 1395 dbSNP
rs149499606 1405 dbSNP
rs894699256 1408 dbSNP
rs914693584 1409 dbSNP
rs147488334 1411 dbSNP
rs1046071839 1412 dbSNP
rs906178552 1414 dbSNP
rs1041890652 1421 dbSNP
rs928844118 1428 dbSNP
rs1377985401 1431 dbSNP
rs536757069 1443 dbSNP
rs534096928 1451 dbSNP
rs774399929 1455 dbSNP
rs952607433 1457 dbSNP
rs1186612743 1463 dbSNP
rs111364237 1468 dbSNP
rs1005302727 1480 dbSNP
rs1407442973 1483 dbSNP
rs1018071357 1498 dbSNP
rs772719457 1499 dbSNP
rs976621124 1502 dbSNP
rs552327327 1509 dbSNP
rs1395713785 1510 dbSNP
rs1283932866 1516 dbSNP
rs922540400 1527 dbSNP
rs894130078 1530 dbSNP
rs1328615084 1531 dbSNP
rs759685674 1543 dbSNP
rs1048167348 1548 dbSNP
rs1400002840 1555 dbSNP
rs1322205968 1561 dbSNP
rs977865217 1562 dbSNP
rs555078656 1567 dbSNP
rs571155055 1568 dbSNP
rs926022988 1582 dbSNP
rs1279639373 1589 dbSNP
rs1004414560 1590 dbSNP
rs1265147590 1592 dbSNP
rs1349439375 1599 dbSNP
rs1487930532 1604 dbSNP
rs1226220258 1608 dbSNP
rs1274777732 1618 dbSNP
rs114055842 1619 dbSNP
rs569926841 1622 dbSNP
rs1223170671 1629 dbSNP
rs1321838967 1649 dbSNP
rs1288677358 1655 dbSNP
rs965645882 1656 dbSNP
rs996699604 1662 dbSNP
rs1028225156 1676 dbSNP
rs953370621 1678 dbSNP
rs916098577 1682 dbSNP
rs138370199 1698 dbSNP
rs1287722425 1699 dbSNP
rs78772317 1702 dbSNP
rs967494122 1703 dbSNP
rs977962686 1708 dbSNP
rs898104412 1714 dbSNP
rs1321822466 1718 dbSNP
rs1411871427 1719 dbSNP
rs1232398538 1720 dbSNP
rs1171153858 1726 dbSNP
rs1477432972 1727 dbSNP
rs1421355358 1733 dbSNP
rs1471711627 1745 dbSNP
rs1192904038 1748 dbSNP
rs760592937 1757 dbSNP
rs1419001718 1760 dbSNP
rs535545494 1766 dbSNP
rs1245696997 1772 dbSNP
rs1475120467 1774 dbSNP
rs181701439 1777 dbSNP
rs993845738 1789 dbSNP
rs1411034236 1790 dbSNP
rs1047172266 1813 dbSNP
rs1340578197 1818 dbSNP
rs753656851 1822 dbSNP
rs1316492556 1824 dbSNP
rs556174642 1828 dbSNP
rs374290399 1829 dbSNP
rs546048453 1829 dbSNP
rs1407588449 1830 dbSNP
rs963833274 1833 dbSNP
rs998009917 1834 dbSNP
rs577525389 1835 dbSNP
rs930963096 1840 dbSNP
rs1048094514 1843 dbSNP
rs768352785 1845 dbSNP
rs1433709621 1850 dbSNP
rs1282226155 1853 dbSNP
rs939800296 1856 dbSNP
rs1228279231 1860 dbSNP
rs1188978503 1870 dbSNP
rs796475340 1879 dbSNP
rs1177683267 1890 dbSNP
rs1456712932 1893 dbSNP
rs1033442206 1895 dbSNP
rs111487945 1896 dbSNP
rs11419240 1896 dbSNP
rs1444933253 1896 dbSNP
rs544756244 1896 dbSNP
rs76493588 1899 dbSNP
rs1374302486 1902 dbSNP
rs564259732 1905 dbSNP
rs1304389368 1908 dbSNP
rs186870578 1909 dbSNP
rs1215122082 1910 dbSNP
rs200024659 1910 dbSNP
rs1273971621 1911 dbSNP
rs1482143649 1912 dbSNP
rs1213279606 1914 dbSNP
rs1258569858 1922 dbSNP
rs1442068903 1926 dbSNP
rs1358468470 1934 dbSNP
rs957415886 1937 dbSNP
rs1185799955 1944 dbSNP
rs991550298 1944 dbSNP
rs77998047 1950 dbSNP
rs76867872 1951 dbSNP
rs191456123 1952 dbSNP
rs1258641821 1953 dbSNP
rs1167891691 1955 dbSNP
rs1388995034 1957 dbSNP
rs1427338009 1960 dbSNP
rs1483151578 1961 dbSNP
rs17445167 1962 dbSNP
rs1047903 1980 dbSNP
rs530005575 1989 dbSNP
rs948154465 1993 dbSNP
rs1375613565 1994 dbSNP
rs996668405 2000 dbSNP
rs1395112870 2002 dbSNP
rs548295076 2005 dbSNP
rs560239277 2015 dbSNP
rs764962380 2016 dbSNP
rs1323759940 2018 dbSNP
rs1483803 2037 dbSNP
rs893724088 2042 dbSNP
rs929554586 2044 dbSNP
rs1011496575 2047 dbSNP
rs527760975 2050 dbSNP
rs1310987425 2051 dbSNP
rs1021638805 2066 dbSNP
rs1401770599 2085 dbSNP
rs1046698996 2087 dbSNP
rs181461840 2088 dbSNP
rs1340137419 2089 dbSNP
rs1423586995 2090 dbSNP
rs143903680 2095 dbSNP
rs757983080 2096 dbSNP
rs1036214990 2099 dbSNP
rs960190028 2110 dbSNP
rs991698241 2111 dbSNP
rs1198985951 2121 dbSNP
rs1489532188 2121 dbSNP
rs1266246094 2132 dbSNP
rs1029920351 2135 dbSNP
rs1320820163 2136 dbSNP
rs916126588 2143 dbSNP
rs1341088398 2156 dbSNP
rs570951954 2173 dbSNP
rs1380005879 2177 dbSNP
rs999194713 2180 dbSNP
rs1032950183 2185 dbSNP
rs1188481630 2188 dbSNP
rs538533582 2191 dbSNP
rs1173307869 2192 dbSNP
rs908221104 2193 dbSNP
rs772898362 2196 dbSNP
rs1192193378 2197 dbSNP
rs550165559 2198 dbSNP
rs79869762 2199 dbSNP
rs1209402654 2200 dbSNP
rs74990748 2201 dbSNP
rs1487640037 2216 dbSNP
rs1395192712 2226 dbSNP
rs939709241 2228 dbSNP
rs971473284 2233 dbSNP
rs1225240449 2234 dbSNP
rs1277474166 2234 dbSNP
rs1332256649 2234 dbSNP
rs981599298 2235 dbSNP
rs568063756 2241 dbSNP
rs1385832344 2242 dbSNP
rs72659527 2244 dbSNP
rs5892570 2245 dbSNP
rs80083030 2245 dbSNP
rs766090572 2251 dbSNP
rs397692769 2253 dbSNP
rs202237947 2254 dbSNP
rs869292017 2254 dbSNP
rs200107708 2255 dbSNP
rs1240239101 2262 dbSNP
rs932448317 2263 dbSNP
rs985433713 2268 dbSNP
rs909503176 2269 dbSNP
rs1319654452 2270 dbSNP
rs1362875952 2276 dbSNP
rs1193947622 2277 dbSNP
rs941029967 2278 dbSNP
rs1443047842 2279 dbSNP
rs1256036864 2287 dbSNP
rs1039349096 2290 dbSNP
rs1049555168 2294 dbSNP
rs1464190666 2303 dbSNP
rs1304212301 2307 dbSNP
rs1310989501 2308 dbSNP
rs1447062713 2312 dbSNP
rs1376547313 2314 dbSNP
rs1330645725 2317 dbSNP
rs751690903 2323 dbSNP
rs1327293058 2328 dbSNP
rs893694632 2330 dbSNP
rs1010795431 2333 dbSNP
rs899559990 2342 dbSNP
rs933750037 2344 dbSNP
rs1050927817 2351 dbSNP
rs1432929860 2356 dbSNP
rs1382322874 2361 dbSNP
rs1021312784 2362 dbSNP
rs1159408783 2364 dbSNP
rs1262781876 2369 dbSNP
rs1439334305 2373 dbSNP
rs1232046535 2377 dbSNP
rs1179440875 2379 dbSNP
rs902994504 2383 dbSNP
rs147254076 2389 dbSNP
rs148714232 2390 dbSNP
rs1266649022 2393 dbSNP
rs1035777006 2399 dbSNP
rs1287555235 2401 dbSNP
rs1240356953 2402 dbSNP
rs1352567264 2412 dbSNP
rs572206385 2431 dbSNP
rs186200375 2433 dbSNP
rs558031577 2434 dbSNP
rs748727297 2448 dbSNP
rs1341505415 2460 dbSNP
rs1334079871 2461 dbSNP
rs756671501 2471 dbSNP
rs760233472 2476 dbSNP
rs893096571 2480 dbSNP
rs1023154730 2481 dbSNP
rs1012882663 2486 dbSNP
rs576112036 2491 dbSNP
rs971442181 2492 dbSNP
rs984375766 2499 dbSNP
rs543418652 2509 dbSNP
rs200392111 2515 dbSNP
rs1473651171 2521 dbSNP
rs1026428765 2525 dbSNP
rs1187062562 2530 dbSNP
rs1484661869 2531 dbSNP
rs543713492 2534 dbSNP
rs189733940 2544 dbSNP
rs1457458289 2545 dbSNP
rs1281681467 2546 dbSNP
rs141599515 2547 dbSNP
rs1357417470 2551 dbSNP
rs1283988404 2552 dbSNP
rs541852993 2553 dbSNP
rs1342972567 2554 dbSNP
rs1462927495 2565 dbSNP
rs1326559065 2566 dbSNP
rs1325695620 2577 dbSNP
rs1343575379 2577 dbSNP
rs1406183887 2577 dbSNP
rs140993242 2577 dbSNP
rs922322320 2578 dbSNP
rs1390098178 2580 dbSNP
rs560103108 2581 dbSNP
rs1425657291 2583 dbSNP
rs1049526107 2591 dbSNP
rs1336526075 2593 dbSNP
rs920949611 2605 dbSNP
rs933691975 2608 dbSNP
rs1451870949 2617 dbSNP
rs915056982 2620 dbSNP
rs1337471118 2623 dbSNP
rs1051271682 2630 dbSNP
rs946572684 2640 dbSNP
rs1212164067 2650 dbSNP
rs1042299886 2655 dbSNP
rs1320466357 2662 dbSNP
rs1279321687 2671 dbSNP
rs386473197 2674 dbSNP
rs774649743 2676 dbSNP
rs1054291554 2677 dbSNP
rs1330703995 2678 dbSNP
rs893026154 2686 dbSNP
rs552204674 2703 dbSNP
rs1252080630 2705 dbSNP
rs564710690 2705 dbSNP
rs370929993 2706 dbSNP
rs895876909 2713 dbSNP
rs1416743267 2715 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control PAR-CLIP data was present in GSM545215. RNA binding protein: AGO4. Condition:Control PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293
Disease 79776.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "HITS-CLIP data was present in GSM714642. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 79776.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065669. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065670. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
Experimental Support 4 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HCT116
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in ERX177599. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_2_1 PAR-CLIP data was present in ERX177611. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_3_1 ...

- Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research.

Article - Krell J; Stebbing J; Carissimi C; Dabrowska et al.
- Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
CLIP-seq Support 1 for dataset GSM714642
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000521891.2 | 3UTR | UAUUAUCUUUAUCAACAUUUGCUGCUACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545212
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / Control
Location of target site ENST00000521891.2 | 3UTR | UAUUAUCUUUAUCAACAUUUGCUGCUACUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM545214
Method / RBP PAR-CLIP / AGO3
Cell line / Condition HEK293 / Control
Location of target site ENST00000521891.2 | 3UTR | UAUUAUCUUUAUCAACAUUUGCUGCUACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM545215
Method / RBP PAR-CLIP / AGO4
Cell line / Condition HEK293 / Control
Location of target site ENST00000521891.2 | 3UTR | CUUUAUCAACAUUUGCUGCUACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000521891.2 | 3UTR | UAUUAUCUUUAUCAACAUUUGCUGCUACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000521891.2 | 3UTR | UAUUAUCUUUAUCAACAUUUGCUGCUACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000521891.2 | 3UTR | UAUUAUCUUUAUCAACAUUUGCUGCUACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000521891.2 | 3UTR | UAUUAUCUUUAUCAACAUUUGCUGCUACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM1065669
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_8
Location of target site ENST00000521891.2 | 3UTR | UAUUAUCUUUAUCAACAUUUGCUGCUACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 10 for dataset GSM1065670
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / 4-thiouridine, 3_ML_LG
Location of target site ENST00000521891.2 | 3UTR | UAUUAUCUUUAUCAACAUUUGCUGCUACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
180 hsa-miR-4524a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055251 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT055826 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT060573 CCND1 cyclin D1 2 2
MIRT061013 C1ORF21 chromosome 1 open reading frame 21 2 6
MIRT064694 CCND2 cyclin D2 2 4
MIRT075268 SNTB2 syntrophin beta 2 2 4
MIRT079668 NAPG NSF attachment protein gamma 2 12
MIRT081651 CCNE1 cyclin E1 2 4
MIRT082996 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT083463 RALGAPB Ral GTPase activating protein non-catalytic beta subunit 2 4
MIRT085755 RIF1 replication timing regulatory factor 1 2 2
MIRT086022 UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 2
MIRT087431 ZNRF3 zinc and ring finger 3 2 2
MIRT088786 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT089221 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT093696 PI4K2B phosphatidylinositol 4-kinase type 2 beta 2 6
MIRT095090 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT096249 CANX calnexin 2 2
MIRT100215 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT100746 VEGFA vascular endothelial growth factor A 2 12
MIRT100904 CD2AP CD2 associated protein 2 2
MIRT102647 UBN2 ubinuclein 2 2 10
MIRT103882 FOXK1 forkhead box K1 2 2
MIRT104246 DMTF1 cyclin D binding myb like transcription factor 1 2 2
MIRT106310 ZFHX4 zinc finger homeobox 4 2 6
MIRT107696 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT114943 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT117671 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT133799 SKI SKI proto-oncogene 2 2
MIRT140167 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT142279 DCTN5 dynactin subunit 5 2 8
MIRT143288 N4BP1 NEDD4 binding protein 1 2 2
MIRT165939 CREBRF CREB3 regulatory factor 2 2
MIRT175251 PSAT1 phosphoserine aminotransferase 1 2 6
MIRT186381 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT191470 PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A 2 2
MIRT196480 TAOK1 TAO kinase 1 2 2
MIRT201470 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 8
MIRT204615 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT204646 MOB4 MOB family member 4, phocein 2 8
MIRT204749 BZW1 basic leucine zipper and W2 domains 1 2 12
MIRT206031 NUP50 nucleoporin 50 2 6
MIRT211196 FGF2 fibroblast growth factor 2 2 4
MIRT229353 ZNF449 zinc finger protein 449 2 2
MIRT247138 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT249461 ZNF691 zinc finger protein 691 2 4
MIRT256314 CDC42SE2 CDC42 small effector 2 2 2
MIRT258419 WIPI2 WD repeat domain, phosphoinositide interacting 2 2 2
MIRT265083 CHEK1 checkpoint kinase 1 2 2
MIRT270561 SETD1B SET domain containing 1B 2 2
MIRT274749 RAB3IP RAB3A interacting protein 2 2
MIRT277515 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 4
MIRT289642 CBX2 chromobox 2 2 2
MIRT301001 MTMR3 myotubularin related protein 3 2 2
MIRT307149 CTDSPL CTD small phosphatase like 2 4
MIRT309021 USP53 ubiquitin specific peptidase 53 2 2
MIRT314100 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 2 8
MIRT319338 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT320619 ZNRF2 zinc and ring finger 2 2 2
MIRT324285 LURAP1L leucine rich adaptor protein 1 like 2 2
MIRT446498 ASCC1 activating signal cointegrator 1 complex subunit 1 2 2
MIRT448437 TLL1 tolloid like 1 2 2
MIRT461537 ACTR3B ARP3 actin related protein 3 homolog B 2 2
MIRT463162 ZNF367 zinc finger protein 367 2 10
MIRT463493 ZC3H10 zinc finger CCCH-type containing 10 2 2
MIRT465154 TSC22D2 TSC22 domain family member 2 2 2
MIRT466418 TFAP2A transcription factor AP-2 alpha 2 8
MIRT468278 SFT2D2 SFT2 domain containing 2 2 2
MIRT469399 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT471941 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT473688 MAPK8 mitogen-activated protein kinase 8 2 4
MIRT479618 CDC25A cell division cycle 25A 2 2
MIRT482098 AKT3 AKT serine/threonine kinase 3 2 4
MIRT483995 ATAD5 ATPase family, AAA domain containing 5 2 12
MIRT485205 PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha 2 8
MIRT498763 C3orf38 chromosome 3 open reading frame 38 2 8
MIRT498961 ORC4 origin recognition complex subunit 4 2 8
MIRT499440 ODF2L outer dense fiber of sperm tails 2 like 2 8
MIRT500080 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 8
MIRT500305 ZNF622 zinc finger protein 622 2 8
MIRT500410 ZMAT3 zinc finger matrin-type 3 2 8
MIRT500789 TLK1 tousled like kinase 1 2 6
MIRT500930 SRPR SRP receptor alpha subunit 2 6
MIRT500943 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 2 8
MIRT501068 SMAD7 SMAD family member 7 2 8
MIRT501711 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT502627 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT502910 CDCA4 cell division cycle associated 4 2 8
MIRT502935 CDC37L1 cell division cycle 37 like 1 2 8
MIRT504531 ZNF620 zinc finger protein 620 2 6
MIRT505106 YTHDC1 YTH domain containing 1 2 6
MIRT505337 TMEM245 transmembrane protein 245 2 6
MIRT505383 TMEM100 transmembrane protein 100 2 2
MIRT505678 SESTD1 SEC14 and spectrin domain containing 1 2 6
MIRT506157 PLAG1 PLAG1 zinc finger 2 8
MIRT506183 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 6
MIRT506475 MYO5A myosin VA 2 6
MIRT506826 KIF23 kinesin family member 23 2 6
MIRT507160 GAS2L3 growth arrest specific 2 like 3 2 2
MIRT507511 DYNLL2 dynein light chain LC8-type 2 2 4
MIRT507845 CCNE2 cyclin E2 2 6
MIRT510403 ZNF507 zinc finger protein 507 2 2
MIRT518078 TRIM35 tripartite motif containing 35 2 2
MIRT518982 NNT nicotinamide nucleotide transhydrogenase 2 4
MIRT521045 SLC2A3 solute carrier family 2 member 3 2 4
MIRT521190 SBNO1 strawberry notch homolog 1 2 6
MIRT522088 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 4
MIRT524846 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT527787 TMEM44 transmembrane protein 44 2 4
MIRT537803 EFNB2 ephrin B2 2 4
MIRT540830 GNAT1 G protein subunit alpha transducin 1 2 4
MIRT541140 PISD phosphatidylserine decarboxylase 2 2
MIRT541419 CBX4 chromobox 4 2 2
MIRT543517 PRSS21 protease, serine 21 2 2
MIRT543824 GSG1 germ cell associated 1 2 2
MIRT544959 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT545179 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 4
MIRT545335 CCDC83 coiled-coil domain containing 83 2 2
MIRT545518 RSL24D1 ribosomal L24 domain containing 1 2 2
MIRT545670 DECR1 2,4-dienoyl-CoA reductase 1 2 2
MIRT545931 ZBTB44 zinc finger and BTB domain containing 44 2 4
MIRT546102 USP48 ubiquitin specific peptidase 48 2 4
MIRT546598 SALL1 spalt like transcription factor 1 2 4
MIRT546626 RTN4 reticulon 4 2 2
MIRT547651 KPNA3 karyopherin subunit alpha 3 2 2
MIRT547987 HCFC2 host cell factor C2 2 4
MIRT548717 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT548931 CDK17 cyclin dependent kinase 17 2 2
MIRT549067 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT549266 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT550460 OSCAR osteoclast associated, immunoglobulin-like receptor 2 4
MIRT550806 FAM229B family with sequence similarity 229 member B 2 2
MIRT552024 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552334 ZNF704 zinc finger protein 704 2 2
MIRT552732 YRDC yrdC N6-threonylcarbamoyltransferase domain containing 2 2
MIRT553795 SZRD1 SUZ RNA binding domain containing 1 2 4
MIRT554694 RNF149 ring finger protein 149 2 2
MIRT555133 PTPRD protein tyrosine phosphatase, receptor type D 2 2
MIRT555264 PRDM4 PR/SET domain 4 2 2
MIRT556848 KANK1 KN motif and ankyrin repeat domains 1 2 4
MIRT557474 GPR27 G protein-coupled receptor 27 2 4
MIRT558018 EXT1 exostosin glycosyltransferase 1 2 2
MIRT558498 CYP26B1 cytochrome P450 family 26 subfamily B member 1 2 4
MIRT558579 CREBL2 cAMP responsive element binding protein like 2 2 4
MIRT558610 COX6B1 cytochrome c oxidase subunit 6B1 2 4
MIRT558650 CNKSR3 CNKSR family member 3 2 2
MIRT558986 CA8 carbonic anhydrase 8 2 2
MIRT559141 BTN3A3 butyrophilin subfamily 3 member A3 2 2
MIRT559327 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT562021 LANCL1 LanC like 1 2 2
MIRT562869 KIAA1456 KIAA1456 2 2
MIRT563074 SLC25A12 solute carrier family 25 member 12 2 2
MIRT563496 DLGAP3 DLG associated protein 3 2 2
MIRT563890 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT564311 CCNT1 cyclin T1 2 2
MIRT564942 XKR7 XK related 7 2 2
MIRT564979 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT565423 TEF TEF, PAR bZIP transcription factor 2 2
MIRT566824 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 2
MIRT571961 KIF5B kinesin family member 5B 2 2
MIRT575877 Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2 3
MIRT576523 Txlna taxilin alpha 2 2
MIRT614693 TRAK1 trafficking kinesin protein 1 2 2
MIRT616065 ZC3H14 zinc finger CCCH-type containing 14 2 2
MIRT618838 ASAH2B N-acylsphingosine amidohydrolase 2B 2 2
MIRT624626 ATXN2 ataxin 2 2 2
MIRT624652 ASAH2 N-acylsphingosine amidohydrolase 2 2 2
MIRT640314 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT659248 CUL3 cullin 3 2 2
MIRT680972 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT682261 RS1 retinoschisin 1 2 2
MIRT682505 GLP2R glucagon like peptide 2 receptor 2 2
MIRT693904 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT699214 SLCO3A1 solute carrier organic anion transporter family member 3A1 2 2
MIRT699373 SLC30A6 solute carrier family 30 member 6 2 2
MIRT699451 SLC16A9 solute carrier family 16 member 9 2 2
MIRT701230 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT702849 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT706163 CASK calcium/calmodulin dependent serine protein kinase 2 3
MIRT718990 UTP15 UTP15, small subunit processome component 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4524a-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-4524a-5p Cetuximab resistant tissue (colorectal carcinoma)

Error report submission