miRTarBase - #MIRT109568


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pre-miRNA Information
pre-miRNA hsa-mir-570   
Genomic Coordinates chr3: 195699401 - 195699497
Synonyms MIRN570, hsa-mir-570, MIR570
Description Homo sapiens miR-570 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies . The 5' end of the miRNA may be offset with respect to previous annotations.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-570-3p
Sequence 60| CGAAAACAGCAAUUACCUUUGC |81
Evidence Experimental
Experiments SAGE
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 5 3 + 195699464 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs562192952 1 dbSNP
rs772001684 2 dbSNP
rs1429248332 7 dbSNP
rs372336246 8 dbSNP
rs1435829348 10 dbSNP
rs1372443221 12 dbSNP
rs1484195269 17 dbSNP
rs1446121044 19 dbSNP
rs761215764 20 dbSNP
rs764570717 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B92RKB miR-570 Predictive Biomarker (PRD) Transcriptomic Data . . . .
Gene Information
Gene Symbol KLHL15   
Synonyms HEL-S-305
Description kelch like family member 15
Transcript NM_030624   
Expression
Putative miRNA Targets on KLHL15
3'UTR of KLHL15
(miRNA target sites are highlighted)		 
>KLHL15|NM_030624|3'UTR
   1 TGACATCCTCCTCCCTAAAAAAAGAGGCAAACAAAGTATTTGTTTGCACAGAGTAATTAATTAAAACATATAAAGAAAAA
  81 CCTCACCAGTTTTACTATCAAAGCCATTGGTCTAACATTGTAAGAATTTTTCATTCTGTGCTAGCATCCTTTTTTTCTTT
 161 TCAGTGGCCTCAAACTCATGCAATAAGTTAATTCTAAGTGCTAGCTCTTGAAACTACTTCCAGAAGCAGTTGAATAGAAT
 241 GCTCCACTTATCTGGGATATTGATTTTCTGCTTTAAACATTTCTTTCAGATGTTAGCGTAGGAGTCATGTGTCTTCTAAG
 321 AGAAGACCCGATAAGTGTCACTGGATGTGATTTCAGTCTCTGTCTCTATCTGAAACCTTTTTGAAGATTTATTTCAGTGT
 401 ATTTCAGTCTGTTATACTTTTTAGTTTTATTATTTAAAAGTTTAAAACTCTTGACCTTTTTGCATGGCTTTTTGCTGAAA
 481 ATGCAAAAATATAAATTTTCTACAAAATTAACTTTTTATATTCAAAACACTATTTCTAAGCTGCCTTCTCTTATCCGCAT
 561 TGTGTTAGTGAAAGCATATTCATACTCGCATACAACCTATAAATACACAAGGCACATCCCTTTTATGCGTGGTTAGGATT
 641 CTATATTTTTAAGCTAGTGCACTTACTTGCACACACAGTTCGCCATACTTGTTGAATTTTAGATGTAACGTCTTTTCACA
 721 TATTAACATTTTTAGAAAGTTGAAATAACTGGAGTCCTCATTTGCTATCAAAGTAGCCTATCTTCAGTCCATACTGATTC
 801 AGTAATATTTGAACTCCTTATATTTCTGAAACATGTATGGTTATGAAAACTAACACTTTATATTTTATTTTCAAAAGTAA
 881 ATGTTAGTGTTCTTTGTCGATGTATGTCTTTTCTTTTTGAAAATGTTTTTCTTTGCAGTCTGTTTAACGTTACCCTGTTT
 961 TTAGTGAGAATCGGAGTGGTATATGACAAGTTCTGGCCCTGCAGCATGCAAGCACTTTTAAAGAGCATTTAGGTAATACC
1041 AGACTCCTAAATCAAGGCCCCTTAAAAGTAAGTGCAACTCCCATTTTTTACATTCAGTAAGGCTGCTGCATTTGTTATTG
1121 AATGGAAGGTAGAAACTCTTAGAAAATTTGACCTCAGTTTTGACTTAGAGGTAAGAAATAGAATTATAATGTTACTGGTT
1201 TTATCTACTTGTTTATTTTGTACAAAATACCCAGCGACACTAGGGATGTAAGCCCTCAGTTTTTGTTTTATTTACTGAAA
1281 GCTATTAGCATGAAGGATAGTAACCACAAAGTTCAGAATGGATCAAGAATAGCTGTTTAAAAGCATTTATAATAAGTGTT
1361 TTAGGATTAGCTGCACCTTTCAACTCTTTAAATGCAGAGGAAAAAACATAGTTGACAAAGTTAAGCAAGAATAACCTGGG
1441 AGTGGATCATTGAAATTGATGCCATTTGCGCATGAGTAGTCTATATCTGATACAGACTAGATCTATACTGGCAAAACTTG
1521 CCAGATCTTAGAATATTGGTGCAATATTGCAATGCCTTCTATATGGCTGCTGATGTATAAATTTTCTAGTTTCACTTTGT
1601 TTGGTGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTTTTTGCTGCTGCCACCATTGAACATAAAATGGAAGTGTGAAGTC
1681 ATGGAAATGTGAAGACTTTGGTTTTTGGGGGTTTTTTGGGCAGTTATTAGACATACTATGAGATTAAACCTGATCTTCAA
1761 ACTCCAGAATTGGAGGCATTTGGGTTTAAGAAACCAGGTACATAAGTAGCTTTTGAAAAAACCATTGGCATTGATTTCAA
1841 AAATCAATAATAATCTTATTTTATATATGAGACTTATATTTTCATTAACTAGTCCTGTCATTTACTTACAGTTTCCAAAC
1921 ATGAAATTTGGTATCTTGTTTCCCATGGTAATATGGGTAAAAGTCTTTTTCTACATTTAAAAAATACATTATTTTATTTT
2001 TGAAAGTTAGGAATAAGTTAGCCATTTAATTTTTTTCTACATTAGTTTAGTGGCTTTGTATGTGTGCTATTTTGCTTTAA
2081 AGAAAATAACGTCTTCATTATTTTCCTCATTGATGTCTTTTGCTAGAAAAGACCAAGAAAGAGCCATCAGGCCAGGTATC
2161 CACATCAAAGCCTTTACACTATAGTGGTGGTTCTCTTTAATTGCTTAGATATGACTTCATGACCCTAGTCAGGGTGACAT
2241 CTGGGCAAACATTTGAGTATTCTTGGTCTTCCATTTTAAAGACAGAGGCCAAGATCAAAGTTCATGTTTTGTAAAATTCG
2321 TAAAATCTTAACTTGAACTAACTCTGGGTTCAGCTTTACGTAAGTCACGTCGGACCTGATGTTAGCTGTAATCAGTTTTG
2401 AGCTTTAAGGATAGTTGCTGTTGCTTGGGTTCTGAATGTATGAGAAAACTCCCTGTTTATATGTAGTTCTAATTTAGGTT
2481 ATTTTAAATCCATGATTAACTTACATTCCCTTTTAAAATTATGGTTTTATTGCTGCAAGAGATTTATTTTTGTTATACTA
2561 AACTATGGAAAAGTTTTTCATAGCATTTTTTTCAAGTTTATTTTTTGTGTGCTTCATTTGGAGTTTTTGTTTATATACAT
2641 TGCGCTCAAAAAAGTAGTTTTTTGAAAAATTCAGTAAGATTTGAATCTATACAGTTTAACTGTTATGACCTTTATGCGTG
2721 TTGTTTTCACTTTATATCTCAAATGCCAGAGTTCACAAAAATAGCTGATCTTCATTAATTACATCTTAATTAGAACCATT
2801 TGTTCTCTTCCGTGTCTTTGACCTTCTAAGTTTTGATTTTAAAGAAATTCCTTGCACTACAGCCTTTTCTTAAAATGCAA
2881 GATTCTCACTTTGAAGGTTTTGTGTTGGAAGAAATGCTACTGGTTTTTAAAAAGCAAAGCTTAACTAATAGAATTATTAG
2961 CTTTTCTTGAGACAGCTTTCTGTGTCCTCATTACTCTGCTCTGTGTGAGTGTTACTAGAATTTGTGAAATACTGACTGAG
3041 CCCTTCACTTATCTTTTCTAAAGCAGCACCTTTGGACACCTCATTCTGGGAAGCCTGCTCGAGTCATAGTAAAGGACACA
3121 CGCTTTATGTGGGGAGAAGTGGTAAAAATGGAGTTTTGTCTTAATTACATGAAACTAAGCTTTAAAATATTTTATAACAG
3201 ATTATTTGAGCTGCATAATCTAAACATGTCAAACGTTCAGTGGGACTATTTTTATATATGTATATGTGGGTGTAGGTCAT
3281 AACATTTCAGTTTATAATATAAATTGTTATTTCAGTTTATAAGCTATCTCTCAGAGGAGACTAGCTCTTTTGAGAATTCA
3361 TAATTTAAAGTTTTAGACTGAAGTAAAATGCAACATAGATAATAGTGTAAATCAGATATAATTGAGGGCTATATGGCAGT
3441 AAAACTGCTAGTGCCAGTTTTCTTGTTTGCCTGTTATACATTTTTGATTTTTGTTTTTGTATTCTGAACATTTTGAGAGA
3521 TCATATGTTTGTTCAATTACATTTAGAGTTGGTTTGGGAATAAATATCTTCTAAAAAGAGATTTATCTTAAAAATGGAAG
3601 TCCTAAAAATTAGTTTATCCAGAGTTTATAAAGTCAAATATTCAGTAGGCATAGACTGGAATAGATAAATTCATGGAAAT
3681 CATATCCTTTCAGTACACCGTATAACTTCAATATTACACAAGTAACATTGAGGAGAATGCCATCAGCTTTGTTCTCCCTT
3761 AAATTCTTTGGTTTTCTTTTTACATTTTGGGAACAACTGCATTTAAAATGTTATTAGTCAGTATATAGTAAGGATTAGGT
3841 GTTTGCTTTCTGAAGGAATGGTCCAGTGAGGTGATTGGGAGAGGTTATTTTCTACCTAACTTGTATATGCCCTATACCTC
3921 TTGGGCATACTTTGTCTATAGAAAAATATTTTGACCTTTAGGTACATTTTGGGCCAGTAGTCAAATAATCCTAGGGCCGA
4001 TATAAAAATCTTAGAATAATTTAAGGTTTGCCTTTTATACCTGTTTTGAAAGCCTTTACATTTTTGTCAGGTAATTTTTC
4081 CCAAGCCGTGGATATAATCTATTCAAACATGTTTATGCTATCCATTCTGTTTTTAAATTGAAAAAAATGTTAAAAGTGTT
4161 TATGAAGAAAAGTTTAAATAAAATATTTTTAATCTTTAAAATATAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cguuuccauuaACGACAAAAGc 5'
                     ||:||||||| 
Target 5' acctttatgcgTGTTGTTTTCa 3'
 2708 - 2729 151.00 -9.20
2 
miRNA  3' cguuuCCAUUAACGACAAAAGc 5'
               |||: || :||||||: 
Target 5' tgtttGGTGTTTTTTGTTTTTt 3'
 1598 - 1619 145.00 -7.70
3 
miRNA  3' cguuuccAUUAACGACAAAAGc 5'
                 |:||| :||||||: 
Target 5' acattttTGATTTTTGTTTTTg 3'
 3478 - 3499 143.00 -10.80
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1478228760 4 dbSNP
rs532904531 5 dbSNP
rs182471953 7 dbSNP
rs780961925 8 dbSNP
rs1268538479 23 dbSNP
rs1463640021 24 dbSNP
rs747838167 24 dbSNP
rs778491924 24 dbSNP
rs1187973000 29 dbSNP
rs1242977940 32 dbSNP
rs754728995 34 dbSNP
rs1215457589 36 dbSNP
rs754754581 37 dbSNP
rs746683646 39 dbSNP
rs753681944 39 dbSNP
rs779934606 47 dbSNP
rs1218702502 51 dbSNP
rs931811959 53 dbSNP
rs1406279162 97 dbSNP
rs964399585 111 dbSNP
rs1387060694 113 dbSNP
rs1433763927 124 dbSNP
rs1320626391 143 dbSNP
rs756253697 150 dbSNP
rs1262223525 157 dbSNP
rs1206787966 162 dbSNP
rs1463538734 163 dbSNP
rs1266923077 164 dbSNP
rs752935513 166 dbSNP
rs1325079550 167 dbSNP
rs1272676992 183 dbSNP
rs1445364461 204 dbSNP
rs1283198950 210 dbSNP
rs1379655843 216 dbSNP
rs56242532 220 dbSNP
rs1053454351 251 dbSNP
rs1266209045 270 dbSNP
rs935044093 283 dbSNP
rs755043687 286 dbSNP
rs760808190 297 dbSNP
rs1320741114 298 dbSNP
rs982152918 304 dbSNP
rs751639571 308 dbSNP
rs1185723730 309 dbSNP
rs1237070005 311 dbSNP
rs776227242 318 dbSNP
rs1470971823 320 dbSNP
rs1190474696 326 dbSNP
rs146597679 329 dbSNP
rs1172188538 330 dbSNP
rs958847462 331 dbSNP
rs1026435984 335 dbSNP
rs1386539559 335 dbSNP
rs775777707 341 dbSNP
rs1333156398 355 dbSNP
rs1340671360 358 dbSNP
rs993752787 367 dbSNP
rs185198388 370 dbSNP
rs1286208355 375 dbSNP
rs866991965 381 dbSNP
rs1349586038 397 dbSNP
rs1228932244 405 dbSNP
rs1373425180 411 dbSNP
rs1190335204 414 dbSNP
rs962397280 415 dbSNP
rs1278236198 421 dbSNP
rs1015016184 425 dbSNP
rs1009305911 429 dbSNP
rs1486118385 436 dbSNP
rs1213218186 440 dbSNP
rs890500917 448 dbSNP
rs1472447143 449 dbSNP
rs1366039270 453 dbSNP
rs907473785 453 dbSNP
rs750713748 454 dbSNP
rs1447449941 456 dbSNP
rs1171484733 464 dbSNP
rs1375747266 488 dbSNP
rs1436209980 490 dbSNP
rs1305721777 492 dbSNP
rs1247267339 495 dbSNP
rs1410147902 496 dbSNP
rs1050284889 503 dbSNP
rs996075892 523 dbSNP
rs772691908 532 dbSNP
rs1462229474 540 dbSNP
rs893735570 546 dbSNP
rs150462731 556 dbSNP
rs1348598875 557 dbSNP
rs1236809682 567 dbSNP
rs935188436 587 dbSNP
rs1482963643 592 dbSNP
rs779479346 593 dbSNP
rs3829712 594 dbSNP
rs1253371996 596 dbSNP
rs1046187938 597 dbSNP
rs1198702701 603 dbSNP
rs949057054 607 dbSNP
rs926536598 610 dbSNP
rs1455161815 612 dbSNP
rs916278624 631 dbSNP
rs990498727 643 dbSNP
rs937553371 654 dbSNP
rs1389143942 658 dbSNP
rs920850489 659 dbSNP
rs1364959956 662 dbSNP
rs903170349 669 dbSNP
rs1299665160 673 dbSNP
rs771157051 681 dbSNP
rs775195971 689 dbSNP
rs1386147134 704 dbSNP
rs1326452685 711 dbSNP
rs1371848821 712 dbSNP
rs1455097808 714 dbSNP
rs1443169948 719 dbSNP
rs1295731213 723 dbSNP
rs1341721336 729 dbSNP
rs1042134299 740 dbSNP
rs973944793 745 dbSNP
rs1354601904 756 dbSNP
rs962269579 757 dbSNP
rs1254117586 771 dbSNP
rs923201959 778 dbSNP
rs1186088307 782 dbSNP
rs1247099430 799 dbSNP
rs975852800 801 dbSNP
rs56051542 809 dbSNP
rs5925970 814 dbSNP
rs1166953668 826 dbSNP
rs1165630005 829 dbSNP
rs1463143361 835 dbSNP
rs943207026 835 dbSNP
rs954859473 856 dbSNP
rs1318612512 860 dbSNP
rs1361293978 864 dbSNP
rs1382992096 866 dbSNP
rs1297942461 867 dbSNP
rs1389346294 872 dbSNP
rs1339097578 878 dbSNP
rs1028920414 882 dbSNP
rs774012696 883 dbSNP
rs770946002 888 dbSNP
rs1184107831 895 dbSNP
rs1473760891 896 dbSNP
rs1235241946 897 dbSNP
rs996149981 898 dbSNP
rs1266953429 902 dbSNP
rs754662844 917 dbSNP
rs1187925586 919 dbSNP
rs375474258 920 dbSNP
rs1423070616 931 dbSNP
rs917968188 936 dbSNP
rs1188389666 949 dbSNP
rs3813165 952 dbSNP
rs1202612329 972 dbSNP
rs1247669854 973 dbSNP
rs371078072 978 dbSNP
rs1290902125 985 dbSNP
rs1400293886 988 dbSNP
rs984551404 989 dbSNP
rs1294277122 990 dbSNP
rs951919247 998 dbSNP
rs1248795809 1001 dbSNP
rs918913069 1002 dbSNP
rs902370978 1003 dbSNP
rs1046558833 1004 dbSNP
rs949136760 1023 dbSNP
rs894916525 1039 dbSNP
rs1253948484 1044 dbSNP
rs1013050940 1058 dbSNP
rs1482718658 1058 dbSNP
rs935308581 1059 dbSNP
rs958852303 1060 dbSNP
rs1033207872 1061 dbSNP
rs1181388938 1062 dbSNP
rs1408592100 1062 dbSNP
rs1306356040 1087 dbSNP
rs1161371131 1090 dbSNP
rs1429407311 1091 dbSNP
rs1434352066 1096 dbSNP
rs1000266028 1099 dbSNP
rs1377676577 1106 dbSNP
rs903283960 1114 dbSNP
rs779484710 1117 dbSNP
rs1225030973 1135 dbSNP
rs1298579278 1141 dbSNP
rs930973519 1141 dbSNP
rs1234615697 1149 dbSNP
rs998600765 1153 dbSNP
rs1346941578 1156 dbSNP
rs1233451335 1167 dbSNP
rs1481566917 1171 dbSNP
rs192286750 1175 dbSNP
rs1040263603 1177 dbSNP
rs943325151 1179 dbSNP
rs1407004994 1184 dbSNP
rs747956618 1190 dbSNP
rs1397086885 1191 dbSNP
rs973719790 1207 dbSNP
rs1170175379 1209 dbSNP
rs1355423461 1211 dbSNP
rs940836258 1215 dbSNP
rs1444998894 1222 dbSNP
rs1292256392 1225 dbSNP
rs1411465492 1226 dbSNP
rs1369635975 1230 dbSNP
rs1440971930 1232 dbSNP
rs1305227934 1236 dbSNP
rs781322688 1236 dbSNP
rs755201545 1252 dbSNP
rs1339627291 1258 dbSNP
rs1162597169 1266 dbSNP
rs1213833097 1268 dbSNP
rs868440789 1270 dbSNP
rs1273459194 1284 dbSNP
rs186977914 1290 dbSNP
rs867817403 1292 dbSNP
rs1253404551 1296 dbSNP
rs988056452 1319 dbSNP
rs147687619 1337 dbSNP
rs1029035024 1346 dbSNP
rs1194336955 1356 dbSNP
rs758448054 1359 dbSNP
rs1255195463 1374 dbSNP
rs1270030308 1379 dbSNP
rs1447906255 1390 dbSNP
rs750917646 1395 dbSNP
rs1224162685 1413 dbSNP
rs12686878 1418 dbSNP
rs1420713399 1430 dbSNP
rs1411956760 1431 dbSNP
rs1394345297 1441 dbSNP
rs1461567002 1457 dbSNP
rs1289742023 1467 dbSNP
rs184024392 1469 dbSNP
rs1362321661 1470 dbSNP
rs1429594452 1471 dbSNP
rs1270371820 1472 dbSNP
rs1032657776 1483 dbSNP
rs999480022 1484 dbSNP
rs41309551 1486 dbSNP
rs971055058 1508 dbSNP
rs1024786592 1509 dbSNP
rs764405313 1519 dbSNP
rs191107097 1521 dbSNP
rs1275134332 1535 dbSNP
rs1445317774 1536 dbSNP
rs1409437852 1539 dbSNP
rs1242889125 1544 dbSNP
rs894864266 1549 dbSNP
rs139996628 1561 dbSNP
rs1305205234 1571 dbSNP
rs958967486 1573 dbSNP
rs1438270272 1575 dbSNP
rs1347939280 1578 dbSNP
rs1322782146 1581 dbSNP
rs767221147 1604 dbSNP
rs1385842888 1608 dbSNP
rs759284933 1613 dbSNP
rs868310421 1613 dbSNP
rs1156388680 1616 dbSNP
rs1346592364 1617 dbSNP
rs187961161 1617 dbSNP
rs770538787 1621 dbSNP
rs773962238 1621 dbSNP
rs1355782676 1627 dbSNP
rs1235097154 1633 dbSNP
rs762422544 1634 dbSNP
rs1192599233 1635 dbSNP
rs199680569 1637 dbSNP
rs553362160 1637 dbSNP
rs559424437 1637 dbSNP
rs747916137 1637 dbSNP
rs752643571 1637 dbSNP
rs1487681760 1638 dbSNP
rs768826024 1640 dbSNP
rs868546101 1641 dbSNP
rs967453107 1641 dbSNP
rs1486179770 1642 dbSNP
rs866584505 1642 dbSNP
rs1038343444 1648 dbSNP
rs1362543363 1649 dbSNP
rs183716909 1660 dbSNP
rs998262577 1681 dbSNP
rs908136760 1706 dbSNP
rs1051898864 1711 dbSNP
rs1375864086 1719 dbSNP
rs375947514 1735 dbSNP
rs192234356 1736 dbSNP
rs1007416019 1745 dbSNP
rs371561332 1759 dbSNP
rs922019389 1760 dbSNP
rs746004121 1761 dbSNP
rs1352848582 1777 dbSNP
rs958020849 1783 dbSNP
rs1349112772 1784 dbSNP
rs1213462021 1794 dbSNP
rs1303630539 1795 dbSNP
rs1048859584 1800 dbSNP
rs1437772543 1805 dbSNP
rs202211933 1822 dbSNP
rs73486003 1823 dbSNP
rs754207761 1824 dbSNP
rs918973680 1830 dbSNP
rs1395275055 1831 dbSNP
rs1436432219 1843 dbSNP
rs1165930196 1845 dbSNP
rs1431369677 1847 dbSNP
rs1036519343 1855 dbSNP
rs1391902638 1856 dbSNP
rs949809395 1859 dbSNP
rs916899685 1865 dbSNP
rs775867659 1869 dbSNP
rs978516825 1877 dbSNP
rs1348852978 1878 dbSNP
rs764587494 1885 dbSNP
rs1249978712 1887 dbSNP
rs1456210925 1887 dbSNP
rs1339093488 1902 dbSNP
rs1406201499 1905 dbSNP
rs1275690619 1909 dbSNP
rs1466779467 1911 dbSNP
rs756591544 1911 dbSNP
rs1253309025 1930 dbSNP
rs1177763969 1945 dbSNP
rs751236207 1948 dbSNP
rs1013416448 1954 dbSNP
rs959231107 1957 dbSNP
rs1033410125 1962 dbSNP
rs1169628321 1963 dbSNP
rs759688083 1965 dbSNP
rs3073993 1985 dbSNP
rs772021806 1985 dbSNP
rs79127910 1985 dbSNP
rs866134388 1985 dbSNP
rs1388773595 1987 dbSNP
rs1293635563 2004 dbSNP
rs1326257616 2008 dbSNP
rs1272492287 2022 dbSNP
rs1431135206 2022 dbSNP
rs898249922 2028 dbSNP
rs1333325200 2029 dbSNP
rs762454599 2031 dbSNP
rs1213556503 2037 dbSNP
rs1424900970 2048 dbSNP
rs991171166 2062 dbSNP
rs774668784 2069 dbSNP
rs1004287235 2091 dbSNP
rs886658408 2093 dbSNP
rs1052486854 2119 dbSNP
rs771515313 2120 dbSNP
rs1246660482 2129 dbSNP
rs1208689297 2144 dbSNP
rs749582387 2144 dbSNP
rs1428941947 2146 dbSNP
rs922134480 2150 dbSNP
rs1415320498 2155 dbSNP
rs1474842508 2156 dbSNP
rs1165511642 2157 dbSNP
rs1395338603 2159 dbSNP
rs1039193669 2167 dbSNP
rs1459486323 2180 dbSNP
rs936735187 2181 dbSNP
rs547159791 2182 dbSNP
rs1257871579 2208 dbSNP
rs1383180815 2212 dbSNP
rs868670724 2212 dbSNP
rs1280509105 2218 dbSNP
rs978911572 2223 dbSNP
rs978084848 2224 dbSNP
rs967945724 2254 dbSNP
rs188877530 2271 dbSNP
rs1367133165 2283 dbSNP
rs1295248111 2284 dbSNP
rs1236215770 2288 dbSNP
rs1259851914 2300 dbSNP
rs1434344973 2302 dbSNP
rs917838032 2310 dbSNP
rs1020484062 2319 dbSNP
rs149512801 2320 dbSNP
rs965459138 2322 dbSNP
rs1485193475 2325 dbSNP
rs1188632313 2326 dbSNP
rs959180120 2342 dbSNP
rs1033483831 2348 dbSNP
rs1464220545 2354 dbSNP
rs1334336770 2359 dbSNP
rs139195303 2360 dbSNP
rs1018209940 2368 dbSNP
rs962450910 2369 dbSNP
rs1006861499 2372 dbSNP
rs1431976227 2378 dbSNP
rs1414531258 2382 dbSNP
rs1314067003 2384 dbSNP
rs150810894 2402 dbSNP
rs1389236879 2412 dbSNP
rs757797794 2416 dbSNP
rs1305680561 2424 dbSNP
rs1316943671 2451 dbSNP
rs1003881182 2459 dbSNP
rs1241899299 2471 dbSNP
rs1277720431 2492 dbSNP
rs1346930653 2493 dbSNP
rs889004250 2504 dbSNP
rs749999414 2515 dbSNP
rs552037394 2523 dbSNP
rs1176487307 2544 dbSNP
rs1249952881 2546 dbSNP
rs1027987393 2555 dbSNP
rs1160732603 2556 dbSNP
rs775684221 2561 dbSNP
rs994805675 2565 dbSNP
rs1434561738 2580 dbSNP
rs1174643700 2593 dbSNP
rs1361195980 2596 dbSNP
rs1460946383 2597 dbSNP
rs866614639 2602 dbSNP
rs897646877 2613 dbSNP
rs890811231 2639 dbSNP
rs1051956078 2640 dbSNP
rs997697361 2641 dbSNP
rs949758133 2643 dbSNP
rs1180124253 2644 dbSNP
rs1369767282 2654 dbSNP
rs895580980 2654 dbSNP
rs900781970 2659 dbSNP
rs1280483356 2661 dbSNP
rs772189641 2673 dbSNP
rs1305513976 2675 dbSNP
rs1055434195 2693 dbSNP
rs1235403718 2704 dbSNP
rs1039138764 2706 dbSNP
rs1180584278 2709 dbSNP
rs936990582 2717 dbSNP
rs745905085 2718 dbSNP
rs778882055 2729 dbSNP
rs979414113 2736 dbSNP
rs946346343 2741 dbSNP
rs1170408890 2764 dbSNP
rs1272271412 2768 dbSNP
rs1227556160 2769 dbSNP
rs1355618528 2793 dbSNP
rs1466782569 2801 dbSNP
rs1323317938 2802 dbSNP
rs141140207 2803 dbSNP
rs945378138 2812 dbSNP
rs1276205994 2822 dbSNP
rs1393731107 2828 dbSNP
rs1377833868 2840 dbSNP
rs1308214250 2843 dbSNP
rs1411316778 2844 dbSNP
rs1296296761 2857 dbSNP
rs1319896820 2859 dbSNP
rs138545582 2868 dbSNP
rs753670873 2874 dbSNP
rs1168427298 2875 dbSNP
rs778476592 2878 dbSNP
rs756536527 2880 dbSNP
rs937885215 2887 dbSNP
rs1222647932 2902 dbSNP
rs1248639525 2903 dbSNP
rs1370648480 2904 dbSNP
rs1186278906 2914 dbSNP
rs1420590497 2949 dbSNP
rs1163321797 2955 dbSNP
rs1479089566 2961 dbSNP
rs763920948 2963 dbSNP
rs1416561552 2974 dbSNP
rs1018324457 2982 dbSNP
rs753182056 2986 dbSNP
rs1325165698 2990 dbSNP
rs1343069945 2996 dbSNP
rs985388233 3009 dbSNP
rs1289244797 3012 dbSNP
rs527618947 3015 dbSNP
rs1342072948 3037 dbSNP
rs1231401839 3038 dbSNP
rs952821241 3040 dbSNP
rs765996122 3046 dbSNP
rs1228957528 3050 dbSNP
rs1027021659 3051 dbSNP
rs995143374 3059 dbSNP
rs973865973 3060 dbSNP
rs183019435 3068 dbSNP
rs1489449426 3072 dbSNP
rs1014736559 3086 dbSNP
rs1204094638 3094 dbSNP
rs1015326829 3100 dbSNP
rs1014103708 3101 dbSNP
rs982968457 3114 dbSNP
rs895526356 3121 dbSNP
rs955164093 3122 dbSNP
rs1267089355 3124 dbSNP
rs1362274143 3127 dbSNP
rs1055548052 3129 dbSNP
rs1029260843 3142 dbSNP
rs1355992533 3159 dbSNP
rs1320555386 3169 dbSNP
rs996473961 3172 dbSNP
rs1348574755 3176 dbSNP
rs937139962 3180 dbSNP
rs904172617 3188 dbSNP
rs1356343860 3189 dbSNP
rs900731306 3194 dbSNP
rs1257503949 3196 dbSNP
rs1443514005 3201 dbSNP
rs1042754991 3202 dbSNP
rs1288478253 3215 dbSNP
rs1229853502 3216 dbSNP
rs946269037 3219 dbSNP
rs1469161867 3234 dbSNP
rs1178908421 3235 dbSNP
rs913500007 3250 dbSNP
rs1041164103 3251 dbSNP
rs944213689 3259 dbSNP
rs1375760376 3262 dbSNP
rs911429677 3271 dbSNP
rs1017848032 3276 dbSNP
rs1334109823 3286 dbSNP
rs1441531289 3290 dbSNP
rs1310355864 3298 dbSNP
rs952856617 3306 dbSNP
rs1232293661 3310 dbSNP
rs1348171933 3311 dbSNP
rs1307045596 3315 dbSNP
rs1387660307 3325 dbSNP
rs749905189 3326 dbSNP
rs1178698808 3333 dbSNP
rs1292261218 3333 dbSNP
rs1457886053 3337 dbSNP
rs764621043 3341 dbSNP
rs761361085 3350 dbSNP
rs1192571107 3351 dbSNP
rs962236245 3352 dbSNP
rs561320257 3360 dbSNP
rs1014851767 3365 dbSNP
rs1166131421 3370 dbSNP
rs776534166 3375 dbSNP
rs1042460372 3380 dbSNP
rs1465224089 3381 dbSNP
rs1332143370 3389 dbSNP
rs1402468276 3391 dbSNP
rs945422659 3402 dbSNP
rs755973578 3423 dbSNP
rs1034212062 3428 dbSNP
rs190789376 3432 dbSNP
rs1235878488 3438 dbSNP
rs938001485 3448 dbSNP
rs1268990401 3472 dbSNP
rs368563938 3477 dbSNP
rs1043087831 3478 dbSNP
rs1207961147 3480 dbSNP
rs1009915477 3489 dbSNP
rs974011368 3499 dbSNP
rs941191271 3503 dbSNP
rs1190745686 3507 dbSNP
rs1041280029 3515 dbSNP
rs908343975 3517 dbSNP
rs1229641380 3521 dbSNP
rs1172682680 3522 dbSNP
rs752924056 3523 dbSNP
rs1326489132 3526 dbSNP
rs760396355 3531 dbSNP
rs1293224022 3532 dbSNP
rs944327596 3535 dbSNP
rs1388681780 3541 dbSNP
rs1321199567 3556 dbSNP
rs767802160 3557 dbSNP
rs1316682191 3573 dbSNP
rs911378357 3585 dbSNP
rs955263193 3585 dbSNP
rs1340245045 3587 dbSNP
rs1029377674 3595 dbSNP
rs975043260 3605 dbSNP
rs931359960 3614 dbSNP
rs963721772 3618 dbSNP
rs1299715331 3619 dbSNP
rs1265727668 3627 dbSNP
rs1386701064 3635 dbSNP
rs1389934046 3644 dbSNP
rs1202931878 3649 dbSNP
rs775279437 3651 dbSNP
rs1323152517 3656 dbSNP
rs1195822880 3667 dbSNP
rs1255311269 3679 dbSNP
rs1474299494 3691 dbSNP
rs1164189772 3694 dbSNP
rs1017792480 3699 dbSNP
rs920029733 3700 dbSNP
rs41311497 3711 dbSNP
rs1156992501 3713 dbSNP
rs904116235 3717 dbSNP
rs1479154792 3722 dbSNP
rs1021515468 3732 dbSNP
rs1009740113 3749 dbSNP
rs1400957685 3765 dbSNP
rs1300665419 3769 dbSNP
rs973105078 3779 dbSNP
rs1395903143 3814 dbSNP
rs1312819936 3816 dbSNP
rs1322958349 3817 dbSNP
rs961396426 3843 dbSNP
rs1259761967 3844 dbSNP
rs1354201924 3851 dbSNP
rs896537561 3860 dbSNP
rs1391661597 3875 dbSNP
rs1196405270 3882 dbSNP
rs917954866 3905 dbSNP
rs1485306216 3907 dbSNP
rs774527570 3908 dbSNP
rs1256974169 3910 dbSNP
rs1425605446 3912 dbSNP
rs1179972566 3914 dbSNP
rs1002201310 3922 dbSNP
rs1248519566 3931 dbSNP
rs1379916760 3939 dbSNP
rs6629782 3941 dbSNP
rs1420756744 3948 dbSNP
rs905223551 3952 dbSNP
rs1034163038 3953 dbSNP
rs1466007767 3961 dbSNP
rs1210551759 3976 dbSNP
rs746109002 3979 dbSNP
rs1038386440 3983 dbSNP
rs1463137778 3990 dbSNP
rs1380775668 3993 dbSNP
rs1389144643 3995 dbSNP
rs941251548 3996 dbSNP
rs908457939 3999 dbSNP
rs1047304253 4014 dbSNP
rs1241782877 4015 dbSNP
rs1277961235 4016 dbSNP
rs1200665022 4019 dbSNP
rs968841393 4026 dbSNP
rs933863106 4030 dbSNP
rs1257655482 4038 dbSNP
rs1346767276 4041 dbSNP
rs1484314674 4060 dbSNP
rs6629781 4070 dbSNP
rs922355242 4087 dbSNP
rs1237585363 4089 dbSNP
rs1021379080 4094 dbSNP
rs1180705501 4099 dbSNP
rs1393682428 4099 dbSNP
rs1253886880 4101 dbSNP
rs774678442 4114 dbSNP
rs1010440830 4136 dbSNP
rs891455096 4138 dbSNP
rs975158521 4140 dbSNP
rs1330097785 4148 dbSNP
rs1400342461 4151 dbSNP
rs1040716837 4158 dbSNP
rs1300773569 4159 dbSNP
rs766789719 4161 dbSNP
rs1303397800 4162 dbSNP
rs1305711740 4183 dbSNP
rs1217869719 4201 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000328046.8 | 3UTR | UUUUCACUUUAUAUCUCAAAUGCCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE42095 Differentiated embryonic stem cells 0.798 2.5e-6 0.613 9.4e-4 23 Click to see details
GSE28544 Breast cancer -0.525 4.2e-3 -0.436 1.7e-2 24 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.495 5.9e-3 0.568 1.5e-3 25 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.942 8.3e-3 1.000 5.0e-1 5 Click to see details
GSE28260 Renal cortex and medulla 0.575 2.0e-2 0.522 3.4e-2 13 Click to see details
GSE32688 Pancreatic cancer -0.307 4.4e-2 -0.337 3.0e-2 32 Click to see details
GSE14794 Lymphoblastoid cells -0.127 1.2e-1 -0.181 4.4e-2 90 Click to see details
GSE26953 Aortic valvular endothelial cells -0.205 1.7e-1 -0.210 1.6e-1 24 Click to see details
GSE17306 Multiple myeloma 0.134 1.8e-1 0.510 9.1e-5 49 Click to see details
GSE21687 Ependynoma primary tumors -0.106 2.0e-1 -0.075 2.8e-1 64 Click to see details
GSE38226 Liver fibrosis 0.174 2.3e-1 0.265 1.2e-1 21 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.177 2.3e-1 0.370 5.4e-2 20 Click to see details
GSE21849 B cell lymphoma -0.136 2.4e-1 0.386 1.9e-2 29 Click to see details
GSE27834 Pluripotent stem cells -0.083 3.8e-1 -0.288 1.4e-1 16 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.007 4.9e-1 -0.037 4.3e-1 25 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.007 4.9e-1 -0.037 4.3e-1 25 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
HNSC -0.358 0.04 -0.333 0.05 26 Click to see details
KIRP -0.333 0.05 -0.305 0.06 26 Click to see details
BLCA 0.484 0.11 0.071 0.43 8 Click to see details
CHOL 0.519 0.12 0.321 0.24 7 Click to see details
LUSC 0.245 0.12 0.346 0.05 25 Click to see details
PAAD 0.743 0.13 0.800 0.1 4 Click to see details
BRCA -0.141 0.24 -0.157 0.21 28 Click to see details
UCEC -0.179 0.25 -0.162 0.27 16 Click to see details
KICH -0.112 0.31 -0.060 0.4 22 Click to see details
THCA 0.08 0.31 0.042 0.4 40 Click to see details
STAD 0.085 0.36 0.061 0.4 19 Click to see details
PRAD -0.084 0.38 -0.121 0.33 15 Click to see details
CESC 0.321 0.4 0.500 0.33 3 Click to see details
ESCA 0.094 0.42 0.143 0.38 7 Click to see details
KIRC -0.021 0.45 -0.014 0.47 32 Click to see details
LIHC -0.002 0.49 0.045 0.38 46 Click to see details
LIHC -0.002 0.49 0.045 0.38 46 Click to see details
LIHC -0.002 0.49 0.045 0.38 46 Click to see details
166 hsa-miR-570-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT053484 CD274 CD274 molecule 2 2
MIRT056153 OTUD1 OTU deubiquitinase 1 2 2
MIRT057406 TNKS2 tankyrase 2 2 2
MIRT065096 SLC38A1 solute carrier family 38 member 1 2 2
MIRT073901 ARL6IP1 ADP ribosylation factor like GTPase 6 interacting protein 1 2 8
MIRT074322 TNRC6A trinucleotide repeat containing 6A 2 8
MIRT077514 UBE2Z ubiquitin conjugating enzyme E2 Z 2 4
MIRT082532 CALM3 calmodulin 3 2 2
MIRT084575 BCL2L11 BCL2 like 11 2 4
MIRT092028 ABHD5 abhydrolase domain containing 5 2 6
MIRT099121 MYLIP myosin regulatory light chain interacting protein 2 8
MIRT102992 RBM33 RNA binding motif protein 33 2 8
MIRT105434 ATP6V1B2 ATPase H+ transporting V1 subunit B2 2 10
MIRT109568 KLHL15 kelch like family member 15 2 2
MIRT145281 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT150161 MIDN midnolin 2 2
MIRT167432 TRIP13 thyroid hormone receptor interactor 13 2 2
MIRT168486 HSPA1B heat shock protein family A (Hsp70) member 1B 2 4
MIRT172128 KLF10 Kruppel like factor 10 4 2
MIRT215596 SUB1 SUB1 homolog, transcriptional regulator 2 2
MIRT259928 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT274852 ATXN7L3B ataxin 7 like 3B 2 4
MIRT290491 C18ORF25 chromosome 18 open reading frame 25 2 2
MIRT290941 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 4
MIRT322703 BAG4 BCL2 associated athanogene 4 2 2
MIRT358568 CANX calnexin 2 2
MIRT381250 RMND5A required for meiotic nuclear division 5 homolog A 2 2
MIRT442077 NDRG1 N-myc downstream regulated 1 2 2
MIRT442943 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT444267 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT444365 TIMM8B translocase of inner mitochondrial membrane 8 homolog B 2 2
MIRT444863 SAMD12 sterile alpha motif domain containing 12 2 2
MIRT444871 ISPD isoprenoid synthase domain containing 2 2
MIRT445077 CXXC4 CXXC finger protein 4 2 2
MIRT445717 NAP1L6 nucleosome assembly protein 1 like 6 2 2
MIRT445945 SCML4 Scm polycomb group protein like 4 2 2
MIRT446054 NR5A2 nuclear receptor subfamily 5 group A member 2 2 2
MIRT446704 FUT10 fucosyltransferase 10 2 2
MIRT446726 SPAG11A sperm associated antigen 11A 2 2
MIRT447147 HHIP hedgehog interacting protein 2 2
MIRT447566 LLPH LLP homolog, long-term synaptic facilitation 2 2
MIRT448698 KLRC4 killer cell lectin like receptor C4 2 2
MIRT448778 GNA13 G protein subunit alpha 13 2 2
MIRT449290 GMNC geminin coiled-coil domain containing 2 2
MIRT449673 SOX3 SRY-box 3 2 2
MIRT450020 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT450089 OR2A4 olfactory receptor family 2 subfamily A member 4 2 2
MIRT450209 PAIP1 poly(A) binding protein interacting protein 1 2 2
MIRT450271 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT450402 TMEM47 transmembrane protein 47 2 2
MIRT450419 BCL2L14 BCL2 like 14 2 2
MIRT450598 EXOC2 exocyst complex component 2 2 2
MIRT450821 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT453007 CCDC115 coiled-coil domain containing 115 2 17
MIRT453857 ZNF12 zinc finger protein 12 2 2
MIRT454706 HMGN1 high mobility group nucleosome binding domain 1 2 4
MIRT458699 LEPREL1 prolyl 3-hydroxylase 2 1 1
MIRT465144 TSC22D2 TSC22 domain family member 2 2 2
MIRT468216 SGK1 serum/glucocorticoid regulated kinase 1 2 2
MIRT469657 RAC1 Rac family small GTPase 1 2 2
MIRT470155 PSME3 proteasome activator subunit 3 2 2
MIRT470287 PRDX5 peroxiredoxin 5 2 2
MIRT470296 PPTC7 PTC7 protein phosphatase homolog 2 2
MIRT472433 NCBP2 nuclear cap binding protein subunit 2 2 2
MIRT472459 NASP nuclear autoantigenic sperm protein 2 2
MIRT475265 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 2
MIRT476735 FOXN2 forkhead box N2 2 2
MIRT476757 FOXK1 forkhead box K1 2 2
MIRT477549 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 2
MIRT478797 CRTAP cartilage associated protein 2 4
MIRT479661 CD164 CD164 molecule 2 4
MIRT479893 CCDC117 coiled-coil domain containing 117 2 4
MIRT480325 C5orf51 chromosome 5 open reading frame 51 2 2
MIRT481229 ATXN7L3 ataxin 7 like 3 2 2
MIRT484088 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT487507 GRK5 G protein-coupled receptor kinase 5 2 2
MIRT488356 PAX2 paired box 2 2 2
MIRT496746 PDIK1L PDLIM1 interacting kinase 1 like 2 2
MIRT496832 ZNF460 zinc finger protein 460 2 2
MIRT500913 STARD13 StAR related lipid transfer domain containing 13 2 4
MIRT502256 HNRNPF heterogeneous nuclear ribonucleoprotein F 2 4
MIRT504078 C9orf40 chromosome 9 open reading frame 40 2 6
MIRT504890 MRPL51 mitochondrial ribosomal protein L51 2 4
MIRT509834 TACR3 tachykinin receptor 3 2 4
MIRT511989 E2F8 E2F transcription factor 8 2 4
MIRT524543 CDC5L cell division cycle 5 like 2 4
MIRT526673 ZNF791 zinc finger protein 791 2 2
MIRT527410 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT528393 PGK1 phosphoglycerate kinase 1 2 2
MIRT529318 PDE5A phosphodiesterase 5A 2 2
MIRT529844 SMTN smoothelin 2 2
MIRT531461 TNFRSF10B TNF receptor superfamily member 10b 2 4
MIRT535096 PODXL podocalyxin like 2 2
MIRT535294 PHF6 PHD finger protein 6 2 2
MIRT537542 ETS1 ETS proto-oncogene 1, transcription factor 2 2
MIRT540200 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT543416 C5orf42 chromosome 5 open reading frame 42 2 2
MIRT543873 SLC16A9 solute carrier family 16 member 9 2 2
MIRT544393 SMC5 structural maintenance of chromosomes 5 2 2
MIRT544919 MBLAC2 metallo-beta-lactamase domain containing 2 2 2
MIRT546579 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT548834 CHD1 chromodomain helicase DNA binding protein 1 2 4
MIRT550787 WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 2 2
MIRT553434 TPM3 tropomyosin 3 2 2
MIRT557467 GRB10 growth factor receptor bound protein 10 2 4
MIRT558065 ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 2 2
MIRT558258 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT559205 BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 2 2
MIRT561072 SRRM4 serine/arginine repetitive matrix 4 2 2
MIRT561805 PAPD5 poly(A) RNA polymerase D5, non-canonical 2 2
MIRT563875 PAGR1 PAXIP1 associated glutamate rich protein 1 2 4
MIRT565835 SCML2 Scm polycomb group protein like 2 2 2
MIRT568049 CHSY1 chondroitin sulfate synthase 1 2 2
MIRT572820 MYO1C myosin IC 2 2
MIRT575423 Epg5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 2 4
MIRT576435 Ccdc115 coiled-coil domain containing 115 2 10
MIRT576533 Txlna taxilin alpha 2 2
MIRT611715 EPG5 ectopic P-granules autophagy protein 5 homolog 2 5
MIRT612574 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit 2 2
MIRT613945 IFIT3 interferon induced protein with tetratricopeptide repeats 3 2 2
MIRT614279 WSCD2 WSC domain containing 2 2 2
MIRT615194 CLUAP1 clusterin associated protein 1 2 2
MIRT627995 MTA3 metastasis associated 1 family member 3 2 2
MIRT637069 DENND2C DENN domain containing 2C 2 2
MIRT639912 SLIT1 slit guidance ligand 1 2 2
MIRT642026 MYADM myeloid associated differentiation marker 2 2
MIRT642844 SLC5A8 solute carrier family 5 member 8 2 2
MIRT643706 ZNF736 zinc finger protein 736 2 2
MIRT643835 RBMY1J RNA binding motif protein, Y-linked, family 1, member J 2 2
MIRT644775 RBMY1B RNA binding motif protein, Y-linked, family 1, member B 2 2
MIRT644778 RBMY1A1 RNA binding motif protein, Y-linked, family 1, member A1 2 2
MIRT644781 RBMY1D RNA binding motif protein, Y-linked, family 1, member D 2 2
MIRT644784 RBMY1E RNA binding motif protein, Y-linked, family 1, member E 2 2
MIRT647495 ZNF639 zinc finger protein 639 2 2
MIRT648248 RBMY1F RNA binding motif protein, Y-linked, family 1, member F 2 2
MIRT648633 LEMD2 LEM domain containing 2 2 2
MIRT654626 PTGFR prostaglandin F receptor 2 2
MIRT656345 MED28 mediator complex subunit 28 2 2
MIRT657354 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2 2
MIRT659635 CDKN2AIP CDKN2A interacting protein 2 2
MIRT659651 CDH4 cadherin 4 2 2
MIRT660959 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT664139 ATP6V1G3 ATPase H+ transporting V1 subunit G3 2 2
MIRT666038 STRBP spermatid perinuclear RNA binding protein 2 2
MIRT666200 SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 2 2
MIRT681712 GDF6 growth differentiation factor 6 2 2
MIRT683276 ZNF99 zinc finger protein 99 2 2
MIRT690312 MRPS30 mitochondrial ribosomal protein S30 2 2
MIRT691642 SLC43A3 solute carrier family 43 member 3 2 2
MIRT692270 GPR157 G protein-coupled receptor 157 2 2
MIRT692840 C1orf50 chromosome 1 open reading frame 50 2 2
MIRT697820 UBQLN1 ubiquilin 1 2 2
MIRT698248 TMEM2 transmembrane protein 2 2 2
MIRT702755 IGF1R insulin like growth factor 1 receptor 2 2
MIRT702918 CRAMP1L cramped chromatin regulator homolog 1 2 2
MIRT703411 FYTTD1 forty-two-three domain containing 1 2 2
MIRT704857 CD46 CD46 molecule 2 2
MIRT711066 BTD biotinidase 2 2
MIRT717794 TGFBR2 transforming growth factor beta receptor 2 2 2
MIRT719676 SPDYE1 speedy/RINGO cell cycle regulator family member E1 2 2
MIRT720300 DDHD1 DDHD domain containing 1 2 2
MIRT723496 WDR33 WD repeat domain 33 2 2
MIRT723934 SVOP SV2 related protein 2 2
MIRT735586 FUT8 fucosyltransferase 8 2 0
MIRT735935 EYA3 EYA transcriptional coactivator and phosphatase 3 3 0
MIRT756075 HDAC1 histone deacetylase 1 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-570 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-570 5-aza-2'-deoxycytidine (5-Aza-CdR) + trichostatin A(TSA) NULL NULL Quantitative real-time PCR gastric cancer AGS cell lines 21960261 2011 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-570-3p Sorafenib 216239 NSC747971 approved sensitive High Hepatocellular Carcinoma cell line (HepG2, Hep-394, Hep-SWX, Huh-7)
hsa-miR-570-3p Doxorubicin 31703 NSC123127 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-570-3p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-570-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-570-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-570-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-570-3p Paclitaxel 36314 NSC125973 approved resistant cell line (SKVO3ip1)
hsa-miR-570-3p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM17)
hsa-miR-570-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (CIS)
hsa-miR-570-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-570-3p Paclitaxel 36314 NSC125973 approved resistant cell line (SKOV3)
hsa-miR-570-3p Oxaliplatin 6857599 NSC266046 approved sensitive cell line (IGROV-1)
hsa-miR-570-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-570-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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