miRTarBase - #MIRT114873


—
pre-miRNA Information
pre-miRNA hsa-mir-4282   
Genomic Coordinates chr6: 72967687 - 72967753
Description Homo sapiens miR-4282 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4282
Sequence 40| UAAAAUUUGCAUCCAGGA |57
Evidence Experimental
Experiments SOLiD
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN32074657 13 COSMIC
COSN6331413 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1195771339 5 dbSNP
rs755058572 6 dbSNP
rs1245753664 11 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol DICER1   
Synonyms DCR1, Dicer, Dicer1e, HERNA, K12H4.8-LIKE, MNG1, RMSE2
Description dicer 1, ribonuclease III
Transcript NM_030621   
Other Transcripts NM_177438   
Expression
Putative miRNA Targets on DICER1
3'UTR of DICER1
(miRNA target sites are highlighted)		 
>DICER1|NM_030621|3'UTR
   1 AACCGCTTTTTAAAATTCAAAACAAGAAACAAAACAAAAAAAATTAAGGGGAAAATTATTTAAATCGGAAAGGAAGACTT
  81 AAAGTTGTTAGTGAGTGGAATGAATTGAAGGCAGAATTTAAAGTTTGGTTGATAACAGGATAGATAACAGAATAAAACAT
 161 TTAACATATGTATAAAATTTTGGAACTAATTGTAGTTTTAGTTTTTTGCGCAAACACAATCTTATCTTCTTTCCTCACTT
 241 CTGCTTTGTTTAAATCACAAGAGTGCTTTAATGATGACATTTAGCAAGTGCTCAAAATAATTGACAGGTTTTGTTTTTTT
 321 TTTTTTGAGTTTATGTCAGCTTTGCTTAGTGTTAGAAGGCCATGGAGCTTAAACCTCCAGCAGTCCCTAGGATGATGTAG
 401 ATTCTTCTCCATCTCTCCGTGTGTGCAGTAGTGCCAGTCCTGCAGTAGTTGATAAGCTGAATAGAAAGATAAGGTTTTCG
 481 AGAGGAGAAGTGCGCCAATGTTGTCTTTTCTTTCCACGTTATACTGTGTAAGGTGATGTTCCCGGTCGCTGTTGCACCTG
 561 ATAGTAAGGGACAGATTTTTAATGAACATTGGCTGGCATGTTGGTGAATCACATTTTAGTTTTCTGATGCCACATAGTCT
 641 TGCATAAAAAAGGGTTCTTGCCTTAAAAGTGAAACCTTCATGGATAGTCTTTAATCTCTGATCTTTTTGGAACAAACTGT
 721 TTTACATTCCTTTCATTTTATTATGCATTAGACGTTGAGACAGCGTGATACTTACAACTCACTAGTATAGTTGTAACTTA
 801 TTACAGGATCATACTAAAATTTCTGTCATATGTATACTGAAGACATTTTAAAAACCAGAATATGTAGTCTACGGATATTT
 881 TTTATCATAAAAATGATCTTTGGCTAAACACCCCATTTTACTAAAGTCCTCCTGCCAGGTAGTTCCCACTGATGGAAATG
 961 TTTATGGCAAATAATTTTGCCTTCTAGGCTGTTGCTCTAACAAAATAAACCTTAGACATATCACACCTAAAATATGCTGC
1041 AGATTTTATAATTGATTGGTTACTTATTTAAGAAGCAAAACACAGCACCTTTACCCTTAGTCTCCTCACATAAATTTCTT
1121 ACTATACTTTTCATAATGTTGCATGCATATTTCACCTACCAAAGCTGTGCTGTTAATGCCGTGAAAGTTTAACGTTTGCG
1201 ATAAACTGCCGTAATTTTGATACATCTGTGATTTAGGTCATTAATTTAGATAAACTAGCTCATTATTTCCATCTTTGGAA
1281 AAGGAAAAAAAAAAAAACTTCTTTAGGCATTTGCCTAAGTTTCTTTAATTAGACTTGTAGGCACTCTTCACTTAAATACC
1361 TCAGTTCTTCTTTTCTTTTGCATGCATTTTTCCCCTGTTTGGTGCTATGTTTATGTATTATGCTTGAAATTTTAATTTTT
1441 TTTTTTTTGCACTGTAACTATAATACCTCTTAATTTACCTTTTTAAAAGCTGTGGGTCAGTCTTGCACTCCCATCAACAT
1521 ACCAGTAGAGGTTTGCTGCAATTTGCCCCGTTAATTATGCTTGAAGTTTAAGAAAGCTGAGCAGAGGTGTCTCATATTTC
1601 CCAGCACATGATTCTGAACTTGATGCTTCGTGGAATGCTGCATTTATATGTAAGTGACATTTGAATACTGTCCTTCCTGC
1681 TTTATCTGCATCATCCACCCACAGAGAAATGCCTCTGTGCGAGTGCACCGACAGAAAACTGTCAGCTCTGCTTTCTAAGG
1761 AACCCTGAGTGAGGGGGGTATTAAGCTTCTCCAGTGTTTTTTGTTGTCTCCAATCTTAAACTTAAATTGAGATCTAAATT
1841 ATTAAACGAGTTTTTGAGCAAATTAGGTGACTTGTTTTAAAAATATTTAATTCCGATTTGGAACCTTAGATGTCTATTTG
1921 ATTTTTTAAAAAACCTTAATGTAAGATATGACCAGTTAAAACAAAGCAATTCTTGAATTATATAACTGTAAAAGTGTGCA
2001 GTTAACAAGGCTGGATGTGAATTTTATTCTGAGGGTGATTTGTGATCAAGTTTAATCACAAATCTCTTAATATTTATAAA
2081 CTACCTGATGCCAGGAGCTTAGGGCTTTGCATTGTGTCTAATACATTGATCCCAGTGTTACGGGATTCTCTTGATTCCTG
2161 GCACCAAAATCAGATTGTTTTCACAGTTATGATTCCCAGTGGGAGAAAAATGCCTCAATATATTTGTAACCTTAAGAAGA
2241 GTATTTTTTTGTTAATACTAAGATGTTCAAACTTAGACATGATTAGGTCATACATTCTCAGGGGTTCAAATTTCCTTCTA
2321 CCATTCAAATGTTTTATCAACAGCAAACTTCAGCCGTTTCACTTTTTGTTGGAGAAAAATAGTAGATTTTAATTTGACTC
2401 ACAGTTTGAAGCATTCTGTGATCCCCTGGTTACTGAGTTAAAAAATAAAAAAGTACGAGTTAGACATATGAAATGGTTAT
2481 GAACGCTTTTGTGCTGCTGATTTTTAATGCTGTAAAGTTTTCCTGTGTTTAGCTTGTTGAAATGTTTTGCATCTGTCAAT
2561 TAAGGAAAAAAAAAATCACTCTATGTTGCCCCACTTTAGAGCCCTGTGTGCCACCCTGTGTTCCTGTGATTGCAATGTGA
2641 GACCGAATGTAATATGGAAAACCTACCAGTGGGGTGTGGTTGTGCCCTGAGCACGTGTGTAAAGGACTGGGGAGGCGTGT
2721 CTTGAAAAAGCAACTGCAGAAATTCCTTATGATGATTGTGTGCAAGTTAGTTAACATGAACCTTCATTTGTAAATTTTTT
2801 AAAATTTCTTTTATAATATGCTTTCCGCAGTCCTAACTATGCTGCGTTTTATAATAGCTTTTTCCCTTCTGTTCTGTTCA
2881 TGTAGCACAGATAAGCATTGCACTTGGTACCATGCTTTACCTCATTTCAAGAAAATATGCTTAACAGAGAGGAAAAAAAT
2961 GTGGTTTGGCCTTGCTGCTGTTTTGATTTATGGAATTTGAAAAAGATAATTATAATGCCTGCAATGTGTCATATACTCGC
3041 ACAACTTAAATAGGTCATTTTTGTCTGTGGCATTTTTACTGTTTGTGAAAGTATGAAACAGATTTGTTAACTGAACTCTT
3121 AATTATGTTTTTAAAATGTTTGTTATATTTCTTTTCTTTTTTCTTTTATATTACGTGAAGTGATGAAATTTAGAATGACC
3201 TCTAACACTCCTGTAATTGTCTTTTAAAATACTGATATTTTTATTTGTTAATAATACTTTGCCCTCAGAAAGATTCTGAT
3281 ACCCTGCCTTGACAACATGAAACTTGAGGCTGCTTTGGTTCATGAATCCAGGTGTTCCCCCGGCAGTCGGCTTCTTCAGT
3361 CGCTCCCTGGAGGCAGGTGGGCACTGCAGAGGATCACTGGAATCCAGATCGAGCGCAGTTCATGCACAAGGCCCCGTTGA
3441 TTTAAAATATTGGATCTTGCTCTGTTAGGGTGTCTAATCCCTTTACACAAGATTGAAGCCACCAAACTGAGACCTTGATA
3521 CCTTTTTTTAACTGCATCTGAAATTATGTTAAGAGTCTTTAACCCATTTGCATTATCTGCAGAAGAGAAACTCATGTCAT
3601 GTTTATTACCTATATGGTTGTTTTAATTACATTTGAATAATTATATTTTTCCAACCACTGATTACTTTTCAGGAATTTAA
3681 TTATTTCCAGATAAATTTCTTTATTTTATATTGTACATGAAAAGTTTTAAAGATATGTTTAAGACCAAGACTATTAAAAT
3761 GATTTTTAAAGTTGTTGGAGACGCCAATAGCAATATCTAGGAAATTTGCATTGAGACCATTGTATTTTCCACTAGCAGTG
3841 AAAATGATTTTTCACAACTAACTTGTAAATATATTTTAATCATTACTTCTTTTTTTCTAGTCCATTTTTATTTGGACATC
3921 AACCACAGACAATTTAAATTTTATAGATGCACTAAGAATTCACTGCAGCAGCAGGTTACATAGCAAAAATGCAAAGGTGA
4001 ACAGGAAGTAAATTTCTGGCTTTTCTGCTGTAAATAGTGAAGGAAAATTACTAAAATCAAGTAAAACTAATGCATATTAT
4081 TTGATTGACAATAAAATATTTACCATCACATGCTGCAGCTGTTTTTTAAGGAACATGATGTCATTCATTCATACAGTAAT
4161 CATGCTGCAGAAATTTGCAGTCTGCACCTTATGGATCACAATTACCTTTAGTTGTTTTTTTTGTAATAATTGTAGCCAAG
4241 TAAATCTCCAATAAAGTTATCGTCTGTTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agGACCUACGUUUAAAAu 5'
            |||||||::|||||| 
Target 5' ggCTGGATGTGAATTTTa 3'
 2009 - 2026 160.00 -16.70
2 
miRNA  3' aggaccuACGUUUAAAAu 5'
                 ||:||||||| 
Target 5' cttcattTGTAAATTTTt 3'
 2782 - 2799 151.00 -5.30
3 
miRNA  3' aggacCUACGUUUAAAAu 5'
               | ||||:||||| 
Target 5' aatatGCTGCAGATTTTa 3'
 1031 - 1048 141.00 -8.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
479616 4 ClinVar
315099 5 ClinVar
388878 20 ClinVar
803045 30 ClinVar
803044 35 ClinVar
885022 57 ClinVar
315098 88 ClinVar
315097 166 ClinVar
885021 175 ClinVar
885020 305 ClinVar
885019 314 ClinVar
315096 327 ClinVar
885018 335 ClinVar
888141 368 ClinVar
888140 381 ClinVar
315095 433 ClinVar
315094 465 ClinVar
888139 497 ClinVar
315093 517 ClinVar
315092 525 ClinVar
315091 754 ClinVar
886862 782 ClinVar
886861 800 ClinVar
315090 806 ClinVar
315089 873 ClinVar
315088 891 ClinVar
886860 901 ClinVar
886859 915 ClinVar
315087 943 ClinVar
315086 981 ClinVar
315085 997 ClinVar
315084 1032 ClinVar
885868 1040 ClinVar
885867 1045 ClinVar
315083 1048 ClinVar
315082 1199 ClinVar
885866 1305 ClinVar
315081 1397 ClinVar
315080 1435 ClinVar
315078 1449 ClinVar
315079 1449 ClinVar
315077 1450 ClinVar
884956 1506 ClinVar
884955 1550 ClinVar
884954 1571 ClinVar
315076 1575 ClinVar
315075 1630 ClinVar
315074 1720 ClinVar
884953 1823 ClinVar
315073 1825 ClinVar
888088 1834 ClinVar
315072 1847 ClinVar
315071 1894 ClinVar
315070 2050 ClinVar
888087 2131 ClinVar
315069 2169 ClinVar
888086 2184 ClinVar
315068 2309 ClinVar
315067 2361 ClinVar
315065 2380 ClinVar
315066 2380 ClinVar
315064 2410 ClinVar
886807 2493 ClinVar
315063 2693 ClinVar
315062 2757 ClinVar
315061 2811 ClinVar
315060 2826 ClinVar
886806 2880 ClinVar
315059 2965 ClinVar
315058 3024 ClinVar
315057 3039 ClinVar
315056 3175 ClinVar
315055 3185 ClinVar
315054 3234 ClinVar
885800 3282 ClinVar
315053 3312 ClinVar
315052 3341 ClinVar
315051 3366 ClinVar
884875 3414 ClinVar
315050 3473 ClinVar
884874 3578 ClinVar
884873 3579 ClinVar
315049 3736 ClinVar
315048 3816 ClinVar
315047 3886 ClinVar
315046 3966 ClinVar
315045 4005 ClinVar
888008 4036 ClinVar
315044 4039 ClinVar
888007 4128 ClinVar
888006 4241 ClinVar
315043 4260 ClinVar
COSN31597566 4 COSMIC
COSN19372515 5 COSMIC
COSN30144525 17 COSMIC
COSN30144527 18 COSMIC
COSN26973395 35 COSMIC
COSN30493553 40 COSMIC
COSN30188170 48 COSMIC
COSN30470935 66 COSMIC
COSN30159647 75 COSMIC
COSN17634982 205 COSMIC
COSN7034472 210 COSMIC
COSN30169352 260 COSMIC
COSN26646148 313 COSMIC
COSN20111642 314 COSMIC
COSN31486408 314 COSMIC
COSN17770008 316 COSMIC
COSN31568600 479 COSMIC
COSN1667039 494 COSMIC
COSN8589141 494 COSMIC
COSN26576145 713 COSMIC
COSN31553681 765 COSMIC
COSN30164575 767 COSMIC
COSN31961029 794 COSMIC
COSN1667038 922 COSMIC
COSN14815642 1285 COSMIC
COSN23742095 1285 COSMIC
COSN20111639 1435 COSMIC
COSN19656369 1449 COSMIC
COSN31589748 1689 COSMIC
COSN26677203 1700 COSMIC
COSN20111638 1716 COSMIC
COSN26549434 2105 COSMIC
COSN31520294 2270 COSMIC
COSN20092879 2320 COSMIC
COSN31552377 2356 COSMIC
COSN30543461 2458 COSMIC
COSN20611756 2606 COSMIC
COSN30172503 3101 COSMIC
COSN26666286 3163 COSMIC
COSN31551245 3195 COSMIC
COSN31591513 3245 COSMIC
COSN8812484 3287 COSMIC
COSN30172577 3389 COSMIC
COSN19498342 3462 COSMIC
COSN25075844 3714 COSMIC
COSN30172310 3761 COSMIC
COSN29821501 3883 COSMIC
COSN31485998 3889 COSMIC
rs35463377 1448 GWAS
rs1057035 2693 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs774611849 4 dbSNP
rs770907156 5 dbSNP
rs1327649737 17 dbSNP
rs1051046532 18 dbSNP
rs200095508 20 dbSNP
rs772958808 23 dbSNP
rs1376753111 24 dbSNP
rs1294935979 25 dbSNP
rs772063181 26 dbSNP
rs749282967 30 dbSNP
rs1169107781 31 dbSNP
rs1315714511 34 dbSNP
rs1384920683 35 dbSNP
rs756294748 35 dbSNP
rs746134430 40 dbSNP
rs1206242179 44 dbSNP
rs1253857284 44 dbSNP
rs748693590 44 dbSNP
rs780675412 44 dbSNP
rs781520963 45 dbSNP
rs1200231957 46 dbSNP
rs757682330 48 dbSNP
rs751956931 49 dbSNP
rs1346211091 54 dbSNP
rs1447007375 55 dbSNP
rs191996364 66 dbSNP
rs528568542 67 dbSNP
rs1429164565 78 dbSNP
rs1172891382 81 dbSNP
rs13078 88 dbSNP
rs1337699534 92 dbSNP
rs776253418 97 dbSNP
rs1332134490 98 dbSNP
rs770494720 111 dbSNP
rs566961540 116 dbSNP
rs1296755923 125 dbSNP
rs914042436 126 dbSNP
rs1215815242 127 dbSNP
rs140021568 134 dbSNP
rs1311267469 139 dbSNP
rs571083676 140 dbSNP
rs960882464 142 dbSNP
rs1338679905 144 dbSNP
rs1264166203 145 dbSNP
rs1414942740 153 dbSNP
rs112795042 166 dbSNP
rs1156544450 169 dbSNP
rs1247943199 170 dbSNP
rs1486268334 170 dbSNP
rs1470965129 181 dbSNP
rs1188371720 184 dbSNP
rs1423068568 194 dbSNP
rs536572479 209 dbSNP
rs186123954 210 dbSNP
rs1182589321 211 dbSNP
rs1455417366 220 dbSNP
rs552609115 223 dbSNP
rs1459632213 225 dbSNP
rs772419252 229 dbSNP
rs981079616 232 dbSNP
rs1206166531 233 dbSNP
rs545752774 243 dbSNP
rs1284766371 248 dbSNP
rs578240601 258 dbSNP
rs1226929425 263 dbSNP
rs1283931383 264 dbSNP
rs1318050318 266 dbSNP
rs1218509492 270 dbSNP
rs1245080765 271 dbSNP
rs1203690710 273 dbSNP
rs1022635227 278 dbSNP
rs1353284110 284 dbSNP
rs180926609 290 dbSNP
rs1158168634 305 dbSNP
rs1310339723 313 dbSNP
rs995643319 314 dbSNP
rs1162569791 315 dbSNP
rs1245490865 316 dbSNP
rs1405021599 317 dbSNP
rs1380732567 318 dbSNP
rs200498201 326 dbSNP
rs1279367976 327 dbSNP
rs1348256191 327 dbSNP
rs1351789558 327 dbSNP
rs35649919 327 dbSNP
rs1317204322 328 dbSNP
rs1288313537 329 dbSNP
rs1448701112 329 dbSNP
rs1344472066 333 dbSNP
rs766170875 335 dbSNP
rs541589888 336 dbSNP
rs758181734 337 dbSNP
rs573788003 339 dbSNP
rs1233289168 351 dbSNP
rs1471020232 359 dbSNP
rs1015381767 361 dbSNP
rs1162588716 362 dbSNP
rs758288467 368 dbSNP
rs146053288 381 dbSNP
rs1386590150 383 dbSNP
rs1181884760 387 dbSNP
rs868741469 391 dbSNP
rs1473416079 394 dbSNP
rs1283007414 395 dbSNP
rs1242114717 407 dbSNP
rs1247269979 411 dbSNP
rs1191648874 414 dbSNP
rs746269429 418 dbSNP
rs537146227 419 dbSNP
rs891004627 421 dbSNP
rs1051417658 431 dbSNP
rs10144436 433 dbSNP
rs899808096 442 dbSNP
rs540370928 447 dbSNP
rs1063608 451 dbSNP
rs1445196731 453 dbSNP
rs1357493791 454 dbSNP
rs557719688 461 dbSNP
rs1294061719 463 dbSNP
rs1063609 464 dbSNP
rs142808371 465 dbSNP
rs1361350285 479 dbSNP
rs796969892 480 dbSNP
rs1432777842 482 dbSNP
rs913968481 488 dbSNP
rs1398170438 492 dbSNP
rs988222541 493 dbSNP
rs113164825 494 dbSNP
rs928163495 497 dbSNP
rs1317735322 498 dbSNP
rs981393854 499 dbSNP
rs138226643 500 dbSNP
rs778577287 505 dbSNP
rs1270784988 511 dbSNP
rs754759594 516 dbSNP
rs779080081 517 dbSNP
rs757448202 518 dbSNP
rs1262301860 520 dbSNP
rs886050939 525 dbSNP
rs1461585104 526 dbSNP
rs1205529398 528 dbSNP
rs973721711 530 dbSNP
rs962394544 543 dbSNP
rs1416745951 544 dbSNP
rs1193297859 547 dbSNP
rs1374229285 548 dbSNP
rs796382591 550 dbSNP
rs1175207504 558 dbSNP
rs1429071592 581 dbSNP
rs548834066 585 dbSNP
rs1470502463 602 dbSNP
rs1339337394 606 dbSNP
rs1382088891 618 dbSNP
rs1319099982 644 dbSNP
rs535308545 650 dbSNP
rs1004000162 653 dbSNP
rs1434643922 661 dbSNP
rs1282850285 662 dbSNP
rs866456511 671 dbSNP
rs1324089895 680 dbSNP
rs890923157 682 dbSNP
rs1265947222 687 dbSNP
rs1029514575 690 dbSNP
rs1205608781 698 dbSNP
rs1263254431 709 dbSNP
rs146319183 715 dbSNP
rs185629513 722 dbSNP
rs1044055742 725 dbSNP
rs946714433 733 dbSNP
rs531021447 753 dbSNP
rs886050938 754 dbSNP
rs1453699942 764 dbSNP
rs1248738927 765 dbSNP
rs1052434786 772 dbSNP
rs1302837155 776 dbSNP
rs567306131 778 dbSNP
rs939441711 780 dbSNP
rs563551631 782 dbSNP
rs1286265075 790 dbSNP
rs980978466 791 dbSNP
rs1262414030 797 dbSNP
rs1270932490 800 dbSNP
rs1216288256 801 dbSNP
rs886050937 806 dbSNP
rs948250041 808 dbSNP
rs766702678 820 dbSNP
rs920837889 823 dbSNP
rs1179506115 825 dbSNP
rs1293803536 832 dbSNP
rs1418829061 834 dbSNP
rs1183252786 859 dbSNP
rs1366045824 864 dbSNP
rs551769486 872 dbSNP
rs45518832 873 dbSNP
rs908208420 877 dbSNP
rs982504653 884 dbSNP
rs955163869 886 dbSNP
rs750494177 891 dbSNP
rs530836779 894 dbSNP
rs964258122 898 dbSNP
rs45467692 901 dbSNP
rs767597538 904 dbSNP
rs1360946843 906 dbSNP
rs1202637009 909 dbSNP
rs181259651 911 dbSNP
rs1250408952 914 dbSNP
rs541737776 915 dbSNP
rs1231274015 921 dbSNP
rs1253019517 927 dbSNP
rs756159471 929 dbSNP
rs1052406850 938 dbSNP
rs1385995402 941 dbSNP
rs574200081 943 dbSNP
rs1045581145 952 dbSNP
rs948244071 963 dbSNP
rs1462625470 964 dbSNP
rs1221590835 967 dbSNP
rs752666806 968 dbSNP
rs920796023 973 dbSNP
rs562287090 981 dbSNP
rs563019682 984 dbSNP
rs1337275020 988 dbSNP
rs762234965 995 dbSNP
rs571363127 997 dbSNP
rs55659064 998 dbSNP
rs1370655181 1000 dbSNP
rs1307723829 1002 dbSNP
rs1229109187 1006 dbSNP
rs1260423615 1013 dbSNP
rs1460244253 1019 dbSNP
rs1299392140 1020 dbSNP
rs1471637149 1025 dbSNP
rs1203635995 1028 dbSNP
rs189661484 1032 dbSNP
rs1462998589 1036 dbSNP
rs185201077 1042 dbSNP
rs886050936 1048 dbSNP
rs1418841568 1051 dbSNP
rs764424935 1054 dbSNP
rs922372205 1060 dbSNP
rs1426989366 1071 dbSNP
rs1469097024 1073 dbSNP
rs1177139072 1076 dbSNP
rs1408228519 1077 dbSNP
rs1468667142 1087 dbSNP
rs1361292426 1089 dbSNP
rs975600130 1093 dbSNP
rs1361980209 1104 dbSNP
rs1177178891 1105 dbSNP
rs1280941572 1110 dbSNP
rs1321943982 1118 dbSNP
rs551595785 1124 dbSNP
rs1405978388 1133 dbSNP
rs539005376 1137 dbSNP
rs1314494502 1143 dbSNP
rs1022085461 1168 dbSNP
rs528282193 1180 dbSNP
rs1242578312 1181 dbSNP
rs1201728184 1190 dbSNP
rs956637901 1193 dbSNP
rs571697838 1196 dbSNP
rs1267021864 1197 dbSNP
rs559333909 1199 dbSNP
rs1199888806 1200 dbSNP
rs1431106973 1201 dbSNP
rs1398906996 1206 dbSNP
rs776308492 1210 dbSNP
rs906567014 1211 dbSNP
rs1214729924 1220 dbSNP
rs1314908404 1223 dbSNP
rs1311070122 1229 dbSNP
rs1344475462 1233 dbSNP
rs1045148658 1239 dbSNP
rs1284347228 1247 dbSNP
rs1012755091 1254 dbSNP
rs1222600692 1265 dbSNP
rs1284174737 1276 dbSNP
rs1381450764 1277 dbSNP
rs1312227925 1278 dbSNP
rs1218904729 1283 dbSNP
rs1451124135 1284 dbSNP
rs1404907560 1285 dbSNP
rs76845545 1285 dbSNP
rs1200346749 1296 dbSNP
rs1248294892 1296 dbSNP
rs578164776 1298 dbSNP
rs899307216 1298 dbSNP
rs908106384 1304 dbSNP
rs940868069 1304 dbSNP
rs1453580453 1305 dbSNP
rs535340548 1305 dbSNP
rs1052053297 1308 dbSNP
rs1279277873 1315 dbSNP
rs1374699843 1327 dbSNP
rs1242901221 1337 dbSNP
rs1313040757 1338 dbSNP
rs933662212 1339 dbSNP
rs1223558222 1348 dbSNP
rs1292290979 1350 dbSNP
rs568193804 1354 dbSNP
rs922267282 1364 dbSNP
rs1203580831 1367 dbSNP
rs1420496569 1373 dbSNP
rs1459049492 1375 dbSNP
rs549910293 1382 dbSNP
rs1384111115 1391 dbSNP
rs1444710674 1392 dbSNP
rs1181773370 1395 dbSNP
rs942463789 1396 dbSNP
rs756671135 1397 dbSNP
rs989262025 1407 dbSNP
rs1185843475 1421 dbSNP
rs542883251 1426 dbSNP
rs148025111 1430 dbSNP
rs866552539 1432 dbSNP
rs570089276 1435 dbSNP
rs1358224734 1436 dbSNP
rs1246791075 1443 dbSNP
rs1288975386 1447 dbSNP
rs1246264292 1448 dbSNP
rs1285975969 1449 dbSNP
rs201612854 1449 dbSNP
rs35463377 1449 dbSNP
rs886050935 1449 dbSNP
rs886050934 1450 dbSNP
rs1314128242 1477 dbSNP
rs1201768237 1485 dbSNP
rs982471790 1487 dbSNP
rs1189023880 1503 dbSNP
rs1461667204 1503 dbSNP
rs529235567 1506 dbSNP
rs772627761 1511 dbSNP
rs1168115695 1517 dbSNP
rs551810526 1521 dbSNP
rs563589355 1522 dbSNP
rs1024061101 1523 dbSNP
rs1467508620 1525 dbSNP
rs375584756 1526 dbSNP
rs1406015100 1529 dbSNP
rs1453931442 1531 dbSNP
rs1336265915 1544 dbSNP
rs771544042 1549 dbSNP
rs193038010 1550 dbSNP
rs1016380652 1558 dbSNP
rs1319816159 1560 dbSNP
rs1005051696 1561 dbSNP
rs1262214897 1568 dbSNP
rs1324216335 1569 dbSNP
rs886639114 1571 dbSNP
rs1281573015 1573 dbSNP
rs190465278 1575 dbSNP
rs757476636 1579 dbSNP
rs1264871332 1589 dbSNP
rs1459565289 1593 dbSNP
rs778892818 1602 dbSNP
rs1197726925 1608 dbSNP
rs148897450 1609 dbSNP
rs1169702189 1618 dbSNP
rs1467042427 1623 dbSNP
rs529576357 1626 dbSNP
rs1426620321 1627 dbSNP
rs1187652 1630 dbSNP
rs1039792469 1637 dbSNP
rs749058420 1642 dbSNP
rs1194042023 1646 dbSNP
rs543949139 1652 dbSNP
rs1403283850 1654 dbSNP
rs1282432022 1658 dbSNP
rs1345877405 1662 dbSNP
rs1490085757 1663 dbSNP
rs1266411477 1671 dbSNP
rs942411707 1675 dbSNP
rs914976738 1677 dbSNP
rs1489730722 1682 dbSNP
rs1211249353 1691 dbSNP
rs1268689734 1700 dbSNP
rs1434111155 1701 dbSNP
rs1201734575 1710 dbSNP
rs1362574956 1713 dbSNP
rs35500699 1720 dbSNP
rs531315737 1720 dbSNP
rs563878612 1721 dbSNP
rs1302756720 1723 dbSNP
rs184814331 1729 dbSNP
rs1388290952 1730 dbSNP
rs1250227907 1739 dbSNP
rs1304512311 1746 dbSNP
rs1335108629 1759 dbSNP
rs923785816 1760 dbSNP
rs1310849948 1762 dbSNP
rs1356620549 1765 dbSNP
rs1244869274 1773 dbSNP
rs1292049568 1775 dbSNP
rs982013263 1778 dbSNP
rs1280499487 1779 dbSNP
rs971064154 1780 dbSNP
rs1382298783 1802 dbSNP
rs1401067414 1803 dbSNP
rs1023579440 1812 dbSNP
rs571735282 1820 dbSNP
rs1369272659 1823 dbSNP
rs886050933 1825 dbSNP
rs1459583983 1827 dbSNP
rs138980290 1828 dbSNP
rs1016349557 1834 dbSNP
rs756438588 1842 dbSNP
rs1380027975 1846 dbSNP
rs886050932 1847 dbSNP
rs1312740656 1848 dbSNP
rs1323170223 1856 dbSNP
rs541770994 1860 dbSNP
rs750594948 1867 dbSNP
rs1425604136 1868 dbSNP
rs1250018375 1870 dbSNP
rs1339114617 1874 dbSNP
rs540809100 1894 dbSNP
rs1030933640 1895 dbSNP
rs997751105 1914 dbSNP
rs1426905340 1927 dbSNP
rs556090668 1928 dbSNP
rs1200592297 1934 dbSNP
rs900739132 1939 dbSNP
rs1249226804 1945 dbSNP
rs1465946163 1949 dbSNP
rs538007258 1952 dbSNP
rs1039312359 1962 dbSNP
rs769292863 1966 dbSNP
rs1302953991 1969 dbSNP
rs191574000 1972 dbSNP
rs893509680 1974 dbSNP
rs1294389295 1975 dbSNP
rs1340369075 1978 dbSNP
rs573381337 1982 dbSNP
rs1260614159 1986 dbSNP
rs1219762419 1990 dbSNP
rs186767104 1996 dbSNP
rs935086203 1998 dbSNP
rs1273399750 2000 dbSNP
rs1484271851 2002 dbSNP
rs923753708 2010 dbSNP
rs1478240035 2014 dbSNP
rs1195607540 2026 dbSNP
rs539919178 2030 dbSNP
rs949269719 2035 dbSNP
rs916479268 2042 dbSNP
rs1450989507 2045 dbSNP
rs1306391165 2049 dbSNP
rs182848457 2050 dbSNP
rs1360780150 2052 dbSNP
rs776800950 2060 dbSNP
rs1402530387 2061 dbSNP
rs963339106 2064 dbSNP
rs547777889 2067 dbSNP
rs983511561 2076 dbSNP
rs1219204240 2091 dbSNP
rs1302586227 2103 dbSNP
rs529563923 2104 dbSNP
rs1213754620 2111 dbSNP
rs1285342239 2121 dbSNP
rs1488758753 2123 dbSNP
rs1399827995 2125 dbSNP
rs375654589 2126 dbSNP
rs1174054818 2127 dbSNP
rs1030446400 2132 dbSNP
rs998075873 2137 dbSNP
rs1362934615 2140 dbSNP
rs964946139 2141 dbSNP
rs752074297 2142 dbSNP
rs1011794406 2153 dbSNP
rs893436013 2157 dbSNP
rs1421177299 2163 dbSNP
rs1053405272 2165 dbSNP
rs192718122 2169 dbSNP
rs1436219024 2170 dbSNP
rs1363149322 2173 dbSNP
rs902240610 2174 dbSNP
rs1046183639 2176 dbSNP
rs1202474079 2177 dbSNP
rs1222526926 2190 dbSNP
rs1346144337 2190 dbSNP
rs1308673611 2193 dbSNP
rs949231811 2197 dbSNP
rs1242660476 2204 dbSNP
rs1238219178 2220 dbSNP
rs1451184715 2222 dbSNP
rs1222044855 2223 dbSNP
rs916425045 2229 dbSNP
rs1055009651 2235 dbSNP
rs1379252410 2240 dbSNP
rs1310013634 2251 dbSNP
rs1380426112 2251 dbSNP
rs941943577 2263 dbSNP
rs909183320 2268 dbSNP
rs1405544334 2281 dbSNP
rs550196410 2282 dbSNP
rs983439647 2294 dbSNP
rs1440716527 2306 dbSNP
rs7158095 2309 dbSNP
rs1377828321 2320 dbSNP
rs775911970 2323 dbSNP
rs1449095511 2326 dbSNP
rs1312940503 2328 dbSNP
rs1355938907 2334 dbSNP
rs1336090341 2337 dbSNP
rs1229061892 2346 dbSNP
rs1414887459 2350 dbSNP
rs1291809597 2355 dbSNP
rs923348310 2355 dbSNP
rs976227310 2356 dbSNP
rs200215778 2361 dbSNP
rs564317468 2361 dbSNP
rs1181242650 2365 dbSNP
rs1236346595 2367 dbSNP
rs140355178 2380 dbSNP
rs188106426 2380 dbSNP
rs1416483843 2386 dbSNP
rs1408570042 2387 dbSNP
rs527349342 2388 dbSNP
rs567592628 2396 dbSNP
rs1401679343 2397 dbSNP
rs1467597540 2401 dbSNP
rs1182376874 2403 dbSNP
rs559735598 2408 dbSNP
rs541765733 2409 dbSNP
rs886050931 2410 dbSNP
rs183501373 2418 dbSNP
rs1359682514 2426 dbSNP
rs1444564480 2427 dbSNP
rs1258418067 2433 dbSNP
rs1236302267 2456 dbSNP
rs902208967 2466 dbSNP
rs1443402750 2481 dbSNP
rs1046534909 2484 dbSNP
rs556464130 2493 dbSNP
rs1189271979 2509 dbSNP
rs1240007183 2512 dbSNP
rs1477257901 2529 dbSNP
rs372370761 2530 dbSNP
rs1286835262 2533 dbSNP
rs894948143 2548 dbSNP
rs779296405 2549 dbSNP
rs1171310498 2555 dbSNP
rs1054977896 2557 dbSNP
rs1245425307 2558 dbSNP
rs1354323945 2560 dbSNP
rs941871335 2568 dbSNP
rs887676239 2572 dbSNP
rs1047716650 2576 dbSNP
rs929291338 2576 dbSNP
rs544177735 2583 dbSNP
rs923305283 2583 dbSNP
rs577139593 2585 dbSNP
rs1325675888 2593 dbSNP
rs1274180117 2597 dbSNP
rs558771191 2613 dbSNP
rs369513768 2626 dbSNP
rs1201688337 2631 dbSNP
rs1281460400 2632 dbSNP
rs1401473800 2636 dbSNP
rs145757043 2644 dbSNP
rs1162530452 2645 dbSNP
rs1478997310 2650 dbSNP
rs957572435 2651 dbSNP
rs1377560009 2652 dbSNP
rs141919532 2662 dbSNP
rs1174421704 2676 dbSNP
rs1031874646 2682 dbSNP
rs1057035 2693 dbSNP
rs568358867 2694 dbSNP
rs760246677 2695 dbSNP
rs1262938353 2696 dbSNP
rs1384868378 2703 dbSNP
rs1322581574 2704 dbSNP
rs1024661120 2708 dbSNP
rs1277305914 2709 dbSNP
rs191724990 2717 dbSNP
rs1489473920 2719 dbSNP
rs749467333 2729 dbSNP
rs1264248537 2736 dbSNP
rs573135025 2757 dbSNP
rs772863817 2766 dbSNP
rs1489679970 2774 dbSNP
rs1208456417 2776 dbSNP
rs1452738847 2780 dbSNP
rs765038526 2780 dbSNP
rs531895007 2781 dbSNP
rs777914593 2787 dbSNP
rs1159261071 2790 dbSNP
rs1382417053 2795 dbSNP
rs887644836 2800 dbSNP
rs186384308 2801 dbSNP
rs1391143380 2804 dbSNP
rs1338597609 2806 dbSNP
rs929244732 2808 dbSNP
rs771539516 2811 dbSNP
rs575292922 2813 dbSNP
rs886050930 2826 dbSNP
rs1040390206 2827 dbSNP
rs1446886154 2830 dbSNP
rs552322819 2839 dbSNP
rs147563014 2845 dbSNP
rs943394672 2846 dbSNP
rs1243577158 2847 dbSNP
rs910632069 2860 dbSNP
rs1357485467 2864 dbSNP
rs1433815780 2866 dbSNP
rs1351147610 2867 dbSNP
rs1212221898 2871 dbSNP
rs1236889807 2880 dbSNP
rs1323580940 2880 dbSNP
rs372590879 2882 dbSNP
rs1179365233 2897 dbSNP
rs1240058095 2901 dbSNP
rs990225981 2902 dbSNP
rs559778560 2903 dbSNP
rs936135259 2922 dbSNP
rs1187076393 2930 dbSNP
rs1368892153 2938 dbSNP
rs1423632011 2941 dbSNP
rs1169150248 2945 dbSNP
rs1479037282 2947 dbSNP
rs1424752059 2949 dbSNP
rs1190866812 2951 dbSNP
rs1459241485 2952 dbSNP
rs1487602441 2952 dbSNP
rs1168185336 2953 dbSNP
rs1399470424 2958 dbSNP
rs537009606 2965 dbSNP
rs1332842485 2968 dbSNP
rs1376322416 2980 dbSNP
rs1222307704 2985 dbSNP
rs1341823933 2986 dbSNP
rs1235548744 2990 dbSNP
rs1256507372 3006 dbSNP
rs1317869575 3008 dbSNP
rs1199784639 3012 dbSNP
rs1396697573 3012 dbSNP
rs1457366104 3013 dbSNP
rs1256142575 3014 dbSNP
rs774193499 3016 dbSNP
rs978052972 3018 dbSNP
rs1200158670 3021 dbSNP
rs886050929 3024 dbSNP
rs756260449 3038 dbSNP
rs768690462 3039 dbSNP
rs1422621229 3040 dbSNP
rs991819605 3041 dbSNP
rs1357000470 3052 dbSNP
rs1465113063 3053 dbSNP
rs1302859614 3061 dbSNP
rs1217130128 3068 dbSNP
rs1403938049 3069 dbSNP
rs1276742807 3070 dbSNP
rs1397706623 3070 dbSNP
rs959339279 3072 dbSNP
rs183203101 3094 dbSNP
rs1298364114 3101 dbSNP
rs529744245 3104 dbSNP
rs1005983613 3116 dbSNP
rs1256610185 3118 dbSNP
rs1484384395 3126 dbSNP
rs1214703181 3127 dbSNP
rs1262283122 3128 dbSNP
rs1488494352 3134 dbSNP
rs1195493969 3136 dbSNP
rs1422991554 3144 dbSNP
rs1440915378 3147 dbSNP
rs1397477427 3151 dbSNP
rs1378828060 3168 dbSNP
rs749200376 3174 dbSNP
rs886050928 3175 dbSNP
rs189898328 3185 dbSNP
rs1400994073 3192 dbSNP
rs199910883 3205 dbSNP
rs1366139441 3206 dbSNP
rs1219112552 3210 dbSNP
rs1302133508 3216 dbSNP
rs993795610 3231 dbSNP
rs1238337453 3232 dbSNP
rs185088366 3234 dbSNP
rs564907544 3243 dbSNP
rs1191976627 3248 dbSNP
rs1439212536 3254 dbSNP
rs1488141121 3257 dbSNP
rs1040730928 3267 dbSNP
rs1236397122 3282 dbSNP
rs565097712 3286 dbSNP
rs1007550157 3287 dbSNP
rs1421085475 3294 dbSNP
rs1161771952 3297 dbSNP
rs1458119435 3297 dbSNP
rs1436472218 3307 dbSNP
rs180705469 3312 dbSNP
rs1373751446 3318 dbSNP
rs1444674059 3321 dbSNP
rs1207839989 3322 dbSNP
rs1308564104 3337 dbSNP
rs889120755 3337 dbSNP
rs1225652686 3339 dbSNP
rs113050387 3341 dbSNP
rs746137769 3342 dbSNP
rs766696071 3342 dbSNP
rs551852272 3345 dbSNP
rs1222822641 3347 dbSNP
rs528603414 3348 dbSNP
rs1041875974 3349 dbSNP
rs1179743698 3357 dbSNP
rs1310753388 3361 dbSNP
rs1449671895 3362 dbSNP
rs751582046 3366 dbSNP
rs1397352046 3371 dbSNP
rs1464484892 3373 dbSNP
rs766135670 3392 dbSNP
rs917505449 3394 dbSNP
rs992186221 3398 dbSNP
rs958992966 3410 dbSNP
rs554286964 3411 dbSNP
rs781473299 3414 dbSNP
rs984518166 3415 dbSNP
rs565849628 3435 dbSNP
rs1378571193 3436 dbSNP
rs1197897906 3437 dbSNP
rs951790677 3442 dbSNP
rs1384575362 3449 dbSNP
rs751638177 3452 dbSNP
rs1026514195 3469 dbSNP
rs3742330 3473 dbSNP
rs1472894234 3490 dbSNP
rs1189135258 3494 dbSNP
rs1255458271 3504 dbSNP
rs1420435690 3517 dbSNP
rs1477157273 3520 dbSNP
rs1170572760 3521 dbSNP
rs1401206136 3522 dbSNP
rs1411734207 3529 dbSNP
rs574809342 3534 dbSNP
rs1332210626 3538 dbSNP
rs529121490 3545 dbSNP
rs966303202 3548 dbSNP
rs1180026083 3553 dbSNP
rs1448976118 3554 dbSNP
rs1314533065 3555 dbSNP
rs186388543 3556 dbSNP
rs1218012148 3563 dbSNP
rs1237801551 3564 dbSNP
rs538167133 3565 dbSNP
rs1216996144 3566 dbSNP
rs1277246725 3578 dbSNP
rs1007889364 3582 dbSNP
rs889090013 3591 dbSNP
rs1350983083 3595 dbSNP
rs1487508991 3596 dbSNP
rs878886499 3596 dbSNP
rs1193312444 3603 dbSNP
rs1374155971 3611 dbSNP
rs1476646752 3613 dbSNP
rs758932903 3614 dbSNP
rs1287542000 3616 dbSNP
rs80121928 3617 dbSNP
rs78663441 3618 dbSNP
rs76409886 3619 dbSNP
rs1240319801 3623 dbSNP
rs1000182035 3626 dbSNP
rs1320575070 3630 dbSNP
rs1262250052 3646 dbSNP
rs1312694588 3651 dbSNP
rs1315002526 3669 dbSNP
rs1394767633 3674 dbSNP
rs1381836455 3690 dbSNP
rs1399181317 3691 dbSNP
rs1298529990 3695 dbSNP
rs1303739277 3696 dbSNP
rs1399643643 3699 dbSNP
rs1328165997 3702 dbSNP
rs1434176656 3708 dbSNP
rs1358940960 3713 dbSNP
rs1273786688 3718 dbSNP
rs1283442143 3736 dbSNP
rs80103767 3736 dbSNP
rs1420437757 3743 dbSNP
rs1042232300 3756 dbSNP
rs1367935758 3756 dbSNP
rs1262818881 3761 dbSNP
rs1449272028 3767 dbSNP
rs950239059 3775 dbSNP
rs1246258807 3776 dbSNP
rs917414834 3780 dbSNP
rs148795970 3782 dbSNP
rs1425438919 3783 dbSNP
rs1414278723 3787 dbSNP
rs1056011240 3789 dbSNP
rs1403594980 3790 dbSNP
rs1322810043 3793 dbSNP
rs1192588819 3796 dbSNP
rs535310119 3805 dbSNP
rs1371551409 3810 dbSNP
rs765598296 3816 dbSNP
rs1306390419 3819 dbSNP
rs926249853 3826 dbSNP
rs1463501948 3835 dbSNP
rs1216854190 3844 dbSNP
rs1240382117 3847 dbSNP
rs181818005 3861 dbSNP
rs1261730176 3882 dbSNP
rs984444798 3885 dbSNP
rs11556997 3886 dbSNP
rs919012849 3889 dbSNP
rs1263120576 3894 dbSNP
rs1195612383 3897 dbSNP
rs1243280229 3902 dbSNP
rs1236402991 3907 dbSNP
rs1439375495 3920 dbSNP
rs1182787225 3922 dbSNP
rs972230345 3929 dbSNP
rs750106160 3931 dbSNP
rs1456201511 3943 dbSNP
rs1162369277 3950 dbSNP
rs965864520 3951 dbSNP
rs1323968536 3954 dbSNP
rs1019210213 3962 dbSNP
rs1294441147 3963 dbSNP
rs532947960 3966 dbSNP
rs1338875884 3967 dbSNP
rs953283982 3971 dbSNP
rs1338279639 3975 dbSNP
rs1243100804 3979 dbSNP
rs1032912964 3980 dbSNP
rs1336162275 3981 dbSNP
rs1300328889 3990 dbSNP
rs1256308325 4002 dbSNP
rs886050927 4005 dbSNP
rs1382953321 4006 dbSNP
rs1390141223 4010 dbSNP
rs529739419 4020 dbSNP
rs1291805809 4034 dbSNP
rs1252940486 4036 dbSNP
rs1422230500 4037 dbSNP
rs112079219 4039 dbSNP
rs1369049314 4041 dbSNP
rs761276152 4061 dbSNP
rs1418260640 4063 dbSNP
rs774018669 4068 dbSNP
rs1020335230 4072 dbSNP
rs1422374358 4076 dbSNP
rs1462063582 4079 dbSNP
rs1299339662 4085 dbSNP
rs1399652994 4090 dbSNP
rs1395059620 4093 dbSNP
rs1312709731 4098 dbSNP
rs1356494847 4108 dbSNP
rs1476744853 4110 dbSNP
rs1276863530 4115 dbSNP
rs1307365736 4117 dbSNP
rs1228270094 4120 dbSNP
rs1014757027 4128 dbSNP
rs1253107678 4128 dbSNP
rs895962647 4135 dbSNP
rs1258033042 4145 dbSNP
rs1056381359 4147 dbSNP
rs1191154175 4155 dbSNP
rs763634343 4163 dbSNP
rs1425461335 4169 dbSNP
rs937523852 4173 dbSNP
rs1429011580 4174 dbSNP
rs1193970838 4185 dbSNP
rs888684231 4187 dbSNP
rs1465289838 4215 dbSNP
rs1048717995 4216 dbSNP
rs930259829 4222 dbSNP
rs1361903310 4223 dbSNP
rs918918852 4223 dbSNP
rs971814253 4223 dbSNP
rs944465555 4225 dbSNP
rs1432186274 4233 dbSNP
rs1310503303 4235 dbSNP
rs1264668951 4240 dbSNP
rs1211039308 4241 dbSNP
rs1233927935 4250 dbSNP
rs1281310132 4251 dbSNP
rs886050926 4260 dbSNP
rs911674521 4261 dbSNP
rs776066400 4262 dbSNP
rs1486182632 4264 dbSNP
rs185087846 4265 dbSNP
rs1188193309 4269 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462573. RNA binding protein: AGO2. Condition:TZM-bl BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_177438 | 3UTR | AAAGUUUGGUUGAUAACAGGAUAGAUAACAGAAUAAAACAUUUAACAUAUGUAUAAAAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1462573
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl BaL
Location of target site ENST00000541352.1 | 3UTR | AAAUUUUAAUUUUUUUUUUUUUGCACUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
280 hsa-miR-4282 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057628 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT060732 RPS3 ribosomal protein S3 2 2
MIRT063371 ETNK1 ethanolamine kinase 1 2 2
MIRT066257 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT070774 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT070871 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT078056 PCTP phosphatidylcholine transfer protein 2 2
MIRT078408 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT084059 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT093537 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096072 SFXN1 sideroflexin 1 2 2
MIRT098316 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT100493 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT102254 HBP1 HMG-box transcription factor 1 2 4
MIRT105318 VPS37A VPS37A, ESCRT-I subunit 2 2
MIRT114143 MZT1 mitotic spindle organizing protein 1 2 4
MIRT114873 DICER1 dicer 1, ribonuclease III 2 2
MIRT134683 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT137640 RCOR1 REST corepressor 1 2 2
MIRT155449 CCNT2 cyclin T2 2 4
MIRT165656 DCTN4 dynactin subunit 4 2 2
MIRT177570 CSTF2T cleavage stimulation factor subunit 2 tau variant 2 4
MIRT188514 E2F7 E2F transcription factor 7 2 10
MIRT193019 TMOD3 tropomodulin 3 2 4
MIRT195823 GADD45A growth arrest and DNA damage inducible alpha 2 2
MIRT195885 DEPDC1 DEP domain containing 1 2 6
MIRT206029 NUP50 nucleoporin 50 2 6
MIRT212148 CLCN3 chloride voltage-gated channel 3 2 2
MIRT213999 DCP2 decapping mRNA 2 2 2
MIRT214650 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2 2
MIRT221568 CBX3 chromobox 3 2 2
MIRT224544 ZNF623 zinc finger protein 623 2 2
MIRT227654 SET SET nuclear proto-oncogene 2 2
MIRT229992 CHIC1 cysteine rich hydrophobic domain 1 2 2
MIRT238968 QKI QKI, KH domain containing RNA binding 2 2
MIRT239825 ACTB actin beta 2 2
MIRT241084 ZXDA zinc finger, X-linked, duplicated A 2 4
MIRT244852 ZBTB5 zinc finger and BTB domain containing 5 2 2
MIRT264534 TARDBP TAR DNA binding protein 2 2
MIRT271438 SKI SKI proto-oncogene 2 2
MIRT271597 ENAH ENAH, actin regulator 2 2
MIRT294332 ZNF264 zinc finger protein 264 2 2
MIRT296341 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT301715 TEF TEF, PAR bZIP transcription factor 2 2
MIRT308549 ZNF654 zinc finger protein 654 2 2
MIRT313866 DEPDC1B DEP domain containing 1B 2 2
MIRT315529 MARCKS myristoylated alanine rich protein kinase C substrate 2 2
MIRT321066 RABGEF1 RAB guanine nucleotide exchange factor 1 2 2
MIRT343777 NUTF2 nuclear transport factor 2 2 2
MIRT359109 MAP1B microtubule associated protein 1B 2 2
MIRT397393 GOLGA3 golgin A3 2 4
MIRT400822 CPEB2 cytoplasmic polyadenylation element binding protein 2 2 2
MIRT442171 DSEL dermatan sulfate epimerase-like 2 2
MIRT442777 JAG1 jagged 1 2 2
MIRT442862 SCARF1 scavenger receptor class F member 1 2 4
MIRT442919 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT444567 TRA2B transformer 2 beta homolog 2 2
MIRT444718 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 2
MIRT445018 RBMS3 RNA binding motif single stranded interacting protein 3 2 2
MIRT445853 LRRC1 leucine rich repeat containing 1 2 2
MIRT446242 HELZ helicase with zinc finger 2 2
MIRT446542 GOLGA8B golgin A8 family member B 2 2
MIRT446643 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT446948 ZMAT3 zinc finger matrin-type 3 2 4
MIRT447061 KCNAB1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 2 2
MIRT447327 ZSCAN21 zinc finger and SCAN domain containing 21 2 2
MIRT447995 CDX1 caudal type homeobox 1 2 2
MIRT448543 RHEBP1 RHEB pseudogene 1 2 6
MIRT448752 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT448772 GOLGA8A golgin A8 family member A 2 2
MIRT449342 WDR26 WD repeat domain 26 2 2
MIRT450011 SLC16A6 solute carrier family 16 member 6 2 4
MIRT450229 PCNX pecanex homolog 1 2 2
MIRT450340 MRPL17 mitochondrial ribosomal protein L17 2 4
MIRT450381 MSI2 musashi RNA binding protein 2 2 2
MIRT450759 PGGT1B protein geranylgeranyltransferase type I subunit beta 2 2
MIRT450809 NRCAM neuronal cell adhesion molecule 2 2
MIRT450947 ATAD2 ATPase family, AAA domain containing 2 2 2
MIRT459095 CCPG1 cell cycle progression 1 2 2
MIRT462428 TWISTNB TWIST neighbor 2 2
MIRT465200 TROVE2 TROVE domain family member 2 2 4
MIRT467382 SON SON DNA binding protein 2 4
MIRT468546 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT471506 PDE4D phosphodiesterase 4D 2 2
MIRT471981 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT474478 KLHL11 kelch like family member 11 2 8
MIRT475011 KANSL1 KAT8 regulatory NSL complex subunit 1 2 8
MIRT480341 C5orf51 chromosome 5 open reading frame 51 2 2
MIRT482696 TEX9 testis expressed 9 2 6
MIRT483462 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 6
MIRT485623 FAM217B family with sequence similarity 217 member B 2 2
MIRT485714 CASP16 caspase 16, pseudogene 2 8
MIRT486279 SEC23A Sec23 homolog A, coat complex II component 2 2
MIRT491000 PEBP1 phosphatidylethanolamine binding protein 1 2 4
MIRT492594 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT493365 KIF5B kinesin family member 5B 2 2
MIRT494316 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT495208 EDN3 endothelin 3 2 2
MIRT497011 TCF15 transcription factor 15 2 2
MIRT498512 FRK fyn related Src family tyrosine kinase 2 2
MIRT498778 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT501045 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 6
MIRT502939 CDC37L1 cell division cycle 37 like 1 2 8
MIRT504806 VHL von Hippel-Lindau tumor suppressor 2 6
MIRT505656 SHMT1 serine hydroxymethyltransferase 1 2 6
MIRT505964 RAB5C RAB5C, member RAS oncogene family 2 6
MIRT506322 OTUD4 OTU deubiquitinase 4 2 4
MIRT506803 KLHL15 kelch like family member 15 2 6
MIRT506917 KBTBD8 kelch repeat and BTB domain containing 8 2 4
MIRT507400 EMC7 ER membrane protein complex subunit 7 2 8
MIRT507471 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 6
MIRT508058 ATP13A3 ATPase 13A3 2 4
MIRT508135 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT509895 RPS23 ribosomal protein S23 2 4
MIRT510881 RAN RAN, member RAS oncogene family 2 8
MIRT513766 PEX5L peroxisomal biogenesis factor 5 like 2 4
MIRT516898 COPS8 COP9 signalosome subunit 8 2 2
MIRT518703 TIMD4 T-cell immunoglobulin and mucin domain containing 4 2 4
MIRT520429 TTPAL alpha tocopherol transfer protein like 2 6
MIRT521843 PNISR PNN interacting serine and arginine rich protein 2 4
MIRT522116 NUDT3 nudix hydrolase 3 2 4
MIRT525467 TMPRSS12 transmembrane protease, serine 12 2 2
MIRT525583 MTRNR2L7 MT-RNR2-like 7 2 2
MIRT525906 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT526072 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT526232 MTRNR2L5 MT-RNR2-like 5 2 4
MIRT526455 FAM71F2 family with sequence similarity 71 member F2 2 4
MIRT526515 POU5F1B POU class 5 homeobox 1B 2 2
MIRT528032 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT528422 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT528995 ISLR2 immunoglobulin superfamily containing leucine rich repeat 2 2 4
MIRT529311 ATRNL1 attractin like 1 2 2
MIRT529376 SKP1 S-phase kinase associated protein 1 2 4
MIRT530015 SRRM1 serine and arginine repetitive matrix 1 2 2
MIRT530089 FMN2 formin 2 2 2
MIRT530942 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2 2
MIRT531229 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT533088 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT533299 USP46 ubiquitin specific peptidase 46 2 2
MIRT533318 UNKL unkempt family like zinc finger 2 2
MIRT533721 TMEM30A transmembrane protein 30A 2 2
MIRT534096 AZF1 azoospermia factor 1 2 2
MIRT534188 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534493 SAR1B secretion associated Ras related GTPase 1B 2 2
MIRT536077 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT536242 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT537524 FAM104A family with sequence similarity 104 member A 2 2
MIRT538088 DGKH diacylglycerol kinase eta 2 2
MIRT538475 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT538853 BTG1 BTG anti-proliferation factor 1 2 4
MIRT539075 GDNF glial cell derived neurotrophic factor 2 2
MIRT539480 ACVR2B activin A receptor type 2B 2 4
MIRT540210 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT541940 TSPAN2 tetraspanin 2 2 2
MIRT543812 COCH cochlin 2 2
MIRT545120 PDZRN4 PDZ domain containing ring finger 4 2 2
MIRT545571 GIMAP4 GTPase, IMAP family member 4 2 2
MIRT545989 XKR4 XK related 4 2 2
MIRT547213 PANK3 pantothenate kinase 3 2 4
MIRT547740 KIAA1468 KIAA1468 2 2
MIRT548022 GRB2 growth factor receptor bound protein 2 2 4
MIRT548032 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548102 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 4
MIRT548217 FKBP1A FK506 binding protein 1A 2 2
MIRT548588 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT548953 CDC27 cell division cycle 27 2 2
MIRT549072 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT550368 INCENP inner centromere protein 2 6
MIRT550546 MYZAP myocardial zonula adherens protein 2 2
MIRT551491 TMEM192 transmembrane protein 192 2 4
MIRT553078 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT554104 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT555127 PTPRG protein tyrosine phosphatase, receptor type G 2 2
MIRT555477 POC1B-GALNT4 POC1B-GALNT4 readthrough 2 2
MIRT555978 NPTN neuroplastin 2 2
MIRT557011 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT557706 GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 2 2
MIRT558333 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT558488 DBN1 drebrin 1 2 2
MIRT559942 ZNF567 zinc finger protein 567 2 2
MIRT561127 ATP2B1 ATPase plasma membrane Ca2+ transporting 1 2 2
MIRT561791 PAWR pro-apoptotic WT1 regulator 2 2
MIRT562438 EEF2 eukaryotic translation elongation factor 2 2 2
MIRT563102 PABPC4L poly(A) binding protein cytoplasmic 4 like 2 2
MIRT563212 ZNF813 zinc finger protein 813 2 2
MIRT563426 KIF3A kinesin family member 3A 2 2
MIRT563473 SPIN4 spindlin family member 4 2 2
MIRT564015 HSPA4 heat shock protein family A (Hsp70) member 4 2 4
MIRT564117 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT564223 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT564503 CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 2 2
MIRT564515 DUSP3 dual specificity phosphatase 3 2 2
MIRT564811 ZBTB21 zinc finger and BTB domain containing 21 2 2
MIRT565265 TPD52 tumor protein D52 2 2
MIRT566012 RHOB ras homolog family member B 2 2
MIRT566216 PTMA prothymosin, alpha 2 2
MIRT566638 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT566821 MAPK8 mitogen-activated protein kinase 8 2 2
MIRT566948 LEPROT leptin receptor overlapping transcript 2 2
MIRT567290 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2 2
MIRT567895 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT568731 MTRNR2L3 MT-RNR2-like 3 2 2
MIRT571263 ZNF239 zinc finger protein 239 2 2
MIRT572593 EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2 2
MIRT573827 TGOLN2 trans-golgi network protein 2 2 2
MIRT576391 Fhl2 four and a half LIM domains 2 2 2
MIRT609901 SMS spermine synthase 2 2
MIRT613710 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 2
MIRT614406 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT615042 DCX doublecortin 2 2
MIRT617514 C5orf45 MRN complex interacting protein 2 2
MIRT619476 PRDM10 PR/SET domain 10 2 2
MIRT620349 TLN1 talin 1 2 2
MIRT620910 PLA2G7 phospholipase A2 group VII 2 2
MIRT622131 SP4 Sp4 transcription factor 2 2
MIRT622955 OTUD7B OTU deubiquitinase 7B 2 2
MIRT623351 MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 2 2
MIRT623619 INTU inturned planar cell polarity protein 2 2
MIRT624409 CCDC171 coiled-coil domain containing 171 2 2
MIRT625171 CCS copper chaperone for superoxide dismutase 2 2
MIRT625685 RPP40 ribonuclease P/MRP subunit p40 2 2
MIRT625875 ALDH18A1 aldehyde dehydrogenase 18 family member A1 2 2
MIRT626002 FAM107A family with sequence similarity 107 member A 2 2
MIRT626872 HRH4 histamine receptor H4 2 4
MIRT628220 FKBP9 FK506 binding protein 9 2 2
MIRT628265 DIO2 iodothyronine deiodinase 2 2 2
MIRT628402 C8orf37 chromosome 8 open reading frame 37 2 2
MIRT630564 C3orf36 chromosome 3 open reading frame 36 2 4
MIRT631577 RASSF9 Ras association domain family member 9 2 2
MIRT635730 CCDC58 coiled-coil domain containing 58 2 2
MIRT636224 SLC8A1 solute carrier family 8 member A1 2 2
MIRT636613 CLIC5 chloride intracellular channel 5 2 2
MIRT638899 CDK9 cyclin dependent kinase 9 2 2
MIRT640167 ATXN7L1 ataxin 7 like 1 2 2
MIRT642070 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT643034 CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 2 2
MIRT644572 SPOP speckle type BTB/POZ protein 2 2
MIRT644954 IFNB1 interferon beta 1 2 2
MIRT645948 TTF2 transcription termination factor 2 2 2
MIRT646440 XRCC2 X-ray repair cross complementing 2 2 2
MIRT647896 EPN2 epsin 2 2 2
MIRT648276 ZNF582 zinc finger protein 582 2 2
MIRT649381 NEDD1 neural precursor cell expressed, developmentally down-regulated 1 2 2
MIRT650254 CD68 CD68 molecule 2 2
MIRT650333 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT651707 VMP1 vacuole membrane protein 1 2 2
MIRT651774 VASP vasodilator stimulated phosphoprotein 2 2
MIRT653144 SRPK2 SRSF protein kinase 2 2 2
MIRT654112 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT654161 RORB RAR related orphan receptor B 2 2
MIRT655716 MLF2 myeloid leukemia factor 2 2 2
MIRT657476 HDAC4 histone deacetylase 4 2 2
MIRT658095 FOXO1 forkhead box O1 2 2
MIRT658860 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT658988 DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 2 2
MIRT660767 ALDH6A1 aldehyde dehydrogenase 6 family member A1 2 2
MIRT661622 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT661694 TFDP2 transcription factor Dp-2 2 2
MIRT662208 PLA2G4E phospholipase A2 group IVE 2 2
MIRT662443 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT664422 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT687505 NECAB1 N-terminal EF-hand calcium binding protein 1 2 2
MIRT689910 SOD2 superoxide dismutase 2 2 2
MIRT690781 PLA2G2C phospholipase A2 group IIC 2 2
MIRT698488 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT699685 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT700926 PDS5A PDS5 cohesin associated factor A 2 2
MIRT702258 LMNB1 lamin B1 2 2
MIRT703166 GPR137C G protein-coupled receptor 137C 2 2
MIRT703242 GNS glucosamine (N-acetyl)-6-sulfatase 2 2
MIRT704737 CENPQ centromere protein Q 2 2
MIRT707310 GLRX2 glutaredoxin 2 2 2
MIRT710021 KCNQ5 potassium voltage-gated channel subfamily Q member 5 2 2
MIRT712212 SCOC short coiled-coil protein 2 2
MIRT714742 SETBP1 SET binding protein 1 2 2
MIRT718268 ZNF749 zinc finger protein 749 2 2
MIRT720553 DYRK4 dual specificity tyrosine phosphorylation regulated kinase 4 2 2
MIRT722248 RBM41 RNA binding motif protein 41 2 2
MIRT723767 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT723977 KIAA0146 scaffolding protein involved in DNA repair 1 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4282 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)

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