miRTarBase - #MIRT119024


—
pre-miRNA Information
pre-miRNA hsa-mir-4742   
Genomic Coordinates chr1: 224398227 - 224398311
Description Homo sapiens miR-4742 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4742-5p
Sequence 1| UCAGGCAAAGGGAUAUUUACAGA |23
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1234293681 4 dbSNP
rs778464201 9 dbSNP
rs758952505 12 dbSNP
rs753463665 16 dbSNP
rs765920862 18 dbSNP
rs1205603801 20 dbSNP
rs756994761 21 dbSNP
Putative Targets

Gene Information
Gene Symbol TSN   
Synonyms BCLF-1, C3PO, RCHF1, REHF-1, TBRBP, TRSLN
Description translin
Transcript NM_004622   
Expression
Putative miRNA Targets on TSN
3'UTR of TSN
(miRNA target sites are highlighted)		 
>TSN|NM_004622|3'UTR
   1 GAGGCTCTCCTTGCTCCTGGCCTTGCTGACCTCAGCGGTTGCCAGGAAGGGGTGAGCACAGAGTGCCTCTTACGGTAGTT
  81 AGGATGCTCAGTTGCTAAACACTGCGCTTTATTTTCTTAACCAGTTGTGGTGTGAGTATCAGAATTGAAACACTTTTTTG
 161 GGGGTAAAAAATATAGCCTTTACATGGACAGAATTTTTTTTGTTGTTTCAGTGAATATGCCTGTAATTCAGTGTATTTCA
 241 GTTCCGTCAGAAAGTGTAAATGTTAGTTTCTTGGTAAAGTCCTTTTCTTGCTTACCTTGACTGTTGATGTACTGATTGAG
 321 AAGTTCATTGTCTCGTTTGTGATTCTTCCAGATGTGATGCTTGATATTTTCTATATGCGAGTTAGCCATCCACACCCAGG
 401 CATAGCCTGGATACAGTATAAAAATAGATAATTAAAAAGATGGTTGCCAAGCAAGGAAAACTTATTTTATATTTTCCCTT
 481 CCTTATTTTAAGCATTGTGAGTAAATCAGATGTTGAATTCTTTTGCCAAGGGAATTATAGCTGCAGGTTCTCTCTCACTG
 561 CCATCAAACTGTAAAAGATTAAACTGCGAAGTCAAGCTCAACAGATTATTTTGGAAAGTTTTTGTATTAAGGGATTTAGT
 641 AACATCATTTTGTTTTCCACCAGGCAGGGAGTAGGGCTTAGTGTTTTAAAACACCTCTGCTTTCTGATGTTGCCTTAATA
 721 TTCTGCTATTGCAGCAATTAAAAATTGTCTTCATGTACATTTGGAACTAACACGTGATGTGATATATTCCTAAACTATGA
 801 AACCTTTTTCCTAGTAGTCAGCTAGATCATTTGTTCTGGGAGTATAAAGCCACCCACGTAAGTTAATAAGCAAAATCCTG
 881 ACTATTATGTTGTTAGAGAAAAATGCTTTGCTTTGTCTGGAAGAAAGATAAAATAGTGAATTATAAATAAGTCAGGCCGG
 961 GCGTGGTGGCTCACACCTGTAATCCCAGCACACTGGGAGGCCGAGGCAGGGGGACTGCTTGAGCTCAGGAGTTCGAGACC
1041 AGCCTGGGCAACAAAGTGAGACTCCATCTCTATATAAAAACAAAAACCACGAAAGCACACACAAAATAAATCAGTGGGAT
1121 TTGGTAATGTGTTTTAGAGTAAGAAATTTCAGGTTGTTGGTGACTATCCCAACAGTCATGTTTTAAATGTACAGTTTGGG
1201 GCAAGTCATGTAAATACTGTTGGTGGTCTTCCCCACACGCCCCAATTTTCAGGTAGTACTAAGAGTATGTGCCAGGAAAC
1281 TCTTGCTATTGAATTGAGATGATTAAAATGGTGACTTAATCCGTAGTTATTTTGCACCCACTGAAAGGAAAGTGCTTTCC
1361 AGAATAATATGAAGTATCTAAAAGTGTCACCTTTTCTTGCCTGATCAACAATTTGGGCTTCCTGTTTGTACAAGGGGCCA
1441 TTTGGCATACCTTTCACAGCTTTTATCAGGCCAAGTTAAAGGCTGACTACATTTTTTCATCATGAGGAAAGCAGTTGAAA
1521 TGAGGCATGAGTTACTGTGCATTGGGATTTTAGAACAATTTTCTTGTGACAGCTCTTTTTGTGAAGTTAGGTTCTTAAAA
1601 GTGCCCATGATGGTCACTTAAAATGTGCAGTAATAGCACTGCCAGGATCAAGCATGAAAGGCTTTTAAATTAGATCATCC
1681 CACAGACAATACGTTTGATAATAGTTTTTTCTTTTAACCTCTTTAAGTATTGATTCTGCTTGAGAATATTGAAGTACTTG
1761 CCAGAAGTTGTGGATTTCAGTTTTAACAAATGCTATTAAAGTGGAGAAGCACACTCTGGTCTTGGAATTCCATTTGAGGA
1841 TTTAGAAGTGTCATGTTTATAACTATTCAGTTGTGTTTGTTGCTGGCTTGTTGTAAAGCAATAAAATTTTTTTGGTCTTT
1921 TTGTAAGTGAGTGTGCTGCTGTAAGAAATCTCCCATGTGCATAACAAATTCTGAATATTTTTTGAGGCTAAAGAAGACCG
2001 GGGTGACAAGCAGATACTGCTGTGTAATGGTTACACTAACCAAAAGACACCAGCCACTCAGAGTTCTATACTGTAAAGCG
2081 CAGATAACATTTGTGTGTTATACCTTGATTGGGGAATTAAAAGTCATTTAACTGAAGATGTTGAGAAACCTGGGCTCTGG
2161 TTTTAGTATACCGGAATTACTTTTTTCCAATTTTAGAAAATCAAGCAGGTTAGAGAAAATAGAGATGAATTAGGGGACAC
2241 TGTCTTATGGATTCATTTATAAGAAGAGAACCAGCCATATACACTTGGGGAGATTTGCCACATCTTAAACTTGAATAATA
2321 GTATGAGTAATGCTTAAGGGAGTTTAATAGAGAAGGAAAGCTTTGGCAGTGTTTTGAGAACTTAAGTGGCTAAAGAGATG
2401 AGACAAACATGCAGGTCGCTACTGGCATAGTTTCATAATTGTGTACTCGGAAATTAAAGTTTGCTTGTTTCTTGGTCTGG
2481 ATTAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agACAUUU--AUAG-GGA----AACGGACu 5'
            | ||||  |:|| |||    ||||||| 
Target 5' taTCTAAAAGTGTCACCTTTTCTTGCCTGa 3'
 1375 - 1404 161.00 -20.80
2 
miRNA  3' agacaUUUAU--AGGGAAACGGACu 5'
               ||||:  |: |||||:||| 
Target 5' gagaaAAATGCTTTGCTTTGTCTGg 3'
 896 - 920 148.00 -13.90
3 
miRNA  3' agaCAUUUAUAGGGAAACGGACu 5'
             | ||||     |||||:|| 
Target 5' ctcGGAAATTAAAGTTTGCTTGt 3'
 2446 - 2468 136.00 -7.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30171534 10 COSMIC
COSN30460396 10 COSMIC
COSN30150338 34 COSMIC
COSN31549828 51 COSMIC
COSN31579895 105 COSMIC
COSN31594369 106 COSMIC
COSN13932528 107 COSMIC
COSN31599953 192 COSMIC
COSN7331661 727 COSMIC
COSN21940980 837 COSMIC
COSN28196263 879 COSMIC
COSN29419723 1282 COSMIC
COSN24538659 1908 COSMIC
COSN1782744 1947 COSMIC
COSN1782745 1954 COSMIC
COSN32079178 2247 COSMIC
COSN22151484 2271 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs764468891 2 dbSNP
rs772599649 4 dbSNP
rs1353715767 6 dbSNP
rs1302535843 10 dbSNP
rs776357604 13 dbSNP
rs1232057930 14 dbSNP
rs1373232593 17 dbSNP
rs761572986 19 dbSNP
rs769544101 23 dbSNP
rs1321056002 25 dbSNP
rs1313107642 29 dbSNP
rs762572850 37 dbSNP
rs766178085 40 dbSNP
rs1459146141 41 dbSNP
rs1199342018 44 dbSNP
rs751545432 45 dbSNP
rs759259489 49 dbSNP
rs545121539 50 dbSNP
rs1427040820 52 dbSNP
rs1052142668 53 dbSNP
rs1172287202 57 dbSNP
rs1472779970 66 dbSNP
rs1451919344 72 dbSNP
rs1048259102 74 dbSNP
rs142031103 75 dbSNP
rs909727483 96 dbSNP
rs1362266297 101 dbSNP
rs939828991 102 dbSNP
rs1163915228 106 dbSNP
rs1442443269 107 dbSNP
rs1367486528 110 dbSNP
rs1403661342 117 dbSNP
rs1037207010 122 dbSNP
rs531962939 125 dbSNP
rs554073391 127 dbSNP
rs146318044 131 dbSNP
rs1308767077 146 dbSNP
rs1333632327 152 dbSNP
rs1286130115 154 dbSNP
rs1359649918 154 dbSNP
rs894812033 160 dbSNP
rs893711986 165 dbSNP
rs1021854744 167 dbSNP
rs1022191430 175 dbSNP
rs1371649285 182 dbSNP
rs963943237 185 dbSNP
rs1170365408 194 dbSNP
rs968890908 194 dbSNP
rs999045570 200 dbSNP
rs1032241191 203 dbSNP
rs1256177867 210 dbSNP
rs1185083032 213 dbSNP
rs180966758 216 dbSNP
rs1275221131 223 dbSNP
rs965524380 232 dbSNP
rs185321035 236 dbSNP
rs1360952432 241 dbSNP
rs1220221096 246 dbSNP
rs1290945111 247 dbSNP
rs1029907321 249 dbSNP
rs921276356 254 dbSNP
rs1480871308 255 dbSNP
rs954012043 263 dbSNP
rs1291679398 268 dbSNP
rs879186921 273 dbSNP
rs1411665351 285 dbSNP
rs1351218828 287 dbSNP
rs954849169 291 dbSNP
rs1178743119 302 dbSNP
rs1248074774 310 dbSNP
rs1418754026 315 dbSNP
rs984016986 323 dbSNP
rs1351982072 328 dbSNP
rs547764056 335 dbSNP
rs987925178 336 dbSNP
rs1387212490 343 dbSNP
rs1473261749 355 dbSNP
rs1422786969 360 dbSNP
rs761990019 374 dbSNP
rs907870071 379 dbSNP
rs1479653903 380 dbSNP
rs1163583712 386 dbSNP
rs1371698791 392 dbSNP
rs961997416 396 dbSNP
rs973641008 397 dbSNP
rs920875806 400 dbSNP
rs948290946 401 dbSNP
rs1271461530 403 dbSNP
rs1230487455 406 dbSNP
rs1329907215 412 dbSNP
rs939156183 416 dbSNP
rs765353750 426 dbSNP
rs894823171 429 dbSNP
rs928116237 435 dbSNP
rs1370290427 455 dbSNP
rs1296810352 456 dbSNP
rs1294637547 457 dbSNP
rs1396173576 463 dbSNP
rs566101170 467 dbSNP
rs1323456482 470 dbSNP
rs1458529408 477 dbSNP
rs539431270 483 dbSNP
rs1157801630 490 dbSNP
rs892142938 493 dbSNP
rs191260224 495 dbSNP
rs6716001 537 dbSNP
rs536860595 539 dbSNP
rs6716004 543 dbSNP
rs1250961060 544 dbSNP
rs996756452 547 dbSNP
rs758901725 551 dbSNP
rs1313666402 555 dbSNP
rs1308012029 564 dbSNP
rs1031877735 566 dbSNP
rs1260376410 567 dbSNP
rs1249427608 568 dbSNP
rs766769138 571 dbSNP
rs1480174306 574 dbSNP
rs1314054437 578 dbSNP
rs1204592773 581 dbSNP
rs901298125 582 dbSNP
rs1302529860 585 dbSNP
rs1029504492 586 dbSNP
rs1028798968 588 dbSNP
rs112047689 589 dbSNP
rs1008999511 591 dbSNP
rs1183074778 594 dbSNP
rs1420229887 597 dbSNP
rs1015396223 598 dbSNP
rs962091851 600 dbSNP
rs1450944345 608 dbSNP
rs1016877225 609 dbSNP
rs1168887169 623 dbSNP
rs1174161733 628 dbSNP
rs973400510 634 dbSNP
rs866211084 635 dbSNP
rs1027611981 640 dbSNP
rs969646977 653 dbSNP
rs1190205719 657 dbSNP
rs534638783 666 dbSNP
rs981397151 673 dbSNP
rs1203638116 674 dbSNP
rs562007081 677 dbSNP
rs577592690 684 dbSNP
rs183469291 689 dbSNP
rs1281185384 693 dbSNP
rs1449931760 698 dbSNP
rs1335537098 699 dbSNP
rs547407876 703 dbSNP
rs1361978601 744 dbSNP
rs1346411374 745 dbSNP
rs988312993 754 dbSNP
rs372870255 755 dbSNP
rs913675500 760 dbSNP
rs563412521 774 dbSNP
rs946446545 780 dbSNP
rs1380216331 784 dbSNP
rs939149137 785 dbSNP
rs990601410 786 dbSNP
rs1433576107 792 dbSNP
rs113050493 795 dbSNP
rs946433563 798 dbSNP
rs1462261087 803 dbSNP
rs899462410 811 dbSNP
rs1043444025 817 dbSNP
rs932555388 834 dbSNP
rs1264707696 838 dbSNP
rs1051427518 848 dbSNP
rs1425851754 854 dbSNP
rs542741258 855 dbSNP
rs149553860 858 dbSNP
rs529495667 859 dbSNP
rs1277340971 868 dbSNP
rs144246262 875 dbSNP
rs774515942 878 dbSNP
rs901353558 878 dbSNP
rs1250017338 884 dbSNP
rs559769773 888 dbSNP
rs533380801 889 dbSNP
rs1336420371 912 dbSNP
rs551449554 921 dbSNP
rs1293533484 923 dbSNP
rs1179038621 927 dbSNP
rs897956200 934 dbSNP
rs1413588946 935 dbSNP
rs1353048068 949 dbSNP
rs994875212 959 dbSNP
rs1027620320 960 dbSNP
rs796581436 963 dbSNP
rs1467927026 964 dbSNP
rs981066527 967 dbSNP
rs1174888885 976 dbSNP
rs1016931304 979 dbSNP
rs1164516832 993 dbSNP
rs1345310540 994 dbSNP
rs148791917 1003 dbSNP
rs1035708663 1004 dbSNP
rs960969195 1006 dbSNP
rs1035322416 1008 dbSNP
rs1437828206 1009 dbSNP
rs960636596 1014 dbSNP
rs1211936797 1015 dbSNP
rs565886613 1026 dbSNP
rs1273375022 1032 dbSNP
rs566934157 1035 dbSNP
rs914064653 1036 dbSNP
rs1280854648 1040 dbSNP
rs1239669166 1041 dbSNP
rs1284988832 1043 dbSNP
rs946454804 1049 dbSNP
rs747728654 1052 dbSNP
rs979134921 1057 dbSNP
rs1326770090 1064 dbSNP
rs1321084298 1066 dbSNP
rs201600824 1071 dbSNP
rs377230844 1071 dbSNP
rs1460108143 1083 dbSNP
rs946485809 1087 dbSNP
rs1285216699 1091 dbSNP
rs920948207 1092 dbSNP
rs1318876517 1096 dbSNP
rs1362526681 1096 dbSNP
rs932279082 1097 dbSNP
rs1201677343 1100 dbSNP
rs1469172916 1103 dbSNP
rs755633910 1105 dbSNP
rs979136571 1108 dbSNP
rs1212679925 1111 dbSNP
rs530955585 1114 dbSNP
rs866750373 1119 dbSNP
rs1466908159 1139 dbSNP
rs1213755916 1141 dbSNP
rs891062416 1152 dbSNP
rs1205131647 1160 dbSNP
rs1277648198 1165 dbSNP
rs1349366542 1165 dbSNP
rs1241526738 1167 dbSNP
rs923608892 1192 dbSNP
rs939952183 1197 dbSNP
rs1438965741 1200 dbSNP
rs1347125714 1203 dbSNP
rs1053390901 1210 dbSNP
rs1400141852 1219 dbSNP
rs1267272216 1222 dbSNP
rs549054585 1223 dbSNP
rs1037308445 1225 dbSNP
rs1394848008 1227 dbSNP
rs898301276 1230 dbSNP
rs1254317764 1236 dbSNP
rs994885026 1239 dbSNP
rs777286320 1240 dbSNP
rs1216088820 1242 dbSNP
rs71426205 1245 dbSNP
rs1027672433 1252 dbSNP
rs749215226 1253 dbSNP
rs770940975 1254 dbSNP
rs905216185 1256 dbSNP
rs79517914 1257 dbSNP
rs1425245724 1259 dbSNP
rs1279538248 1261 dbSNP
rs386649842 1265 dbSNP
rs58389574 1266 dbSNP
rs114855840 1267 dbSNP
rs1430331855 1270 dbSNP
rs1435484912 1272 dbSNP
rs1314913191 1274 dbSNP
rs1035013362 1280 dbSNP
rs1435435892 1280 dbSNP
rs748010897 1285 dbSNP
rs1375810287 1286 dbSNP
rs1420725311 1287 dbSNP
rs75795205 1289 dbSNP
rs1012166574 1309 dbSNP
rs1283679896 1317 dbSNP
rs777009786 1323 dbSNP
rs968182782 1324 dbSNP
rs188406201 1336 dbSNP
rs556728876 1338 dbSNP
rs1023475292 1342 dbSNP
rs967839889 1348 dbSNP
rs539931650 1360 dbSNP
rs979188849 1368 dbSNP
rs575303133 1371 dbSNP
rs956465684 1378 dbSNP
rs1354922770 1380 dbSNP
rs1311566598 1381 dbSNP
rs1445037474 1385 dbSNP
rs953805027 1397 dbSNP
rs1170258621 1403 dbSNP
rs1408585649 1407 dbSNP
rs922955033 1412 dbSNP
rs1166673328 1416 dbSNP
rs986913402 1417 dbSNP
rs1416579280 1428 dbSNP
rs1185708707 1431 dbSNP
rs192083163 1433 dbSNP
rs1233403255 1438 dbSNP
rs1241461104 1441 dbSNP
rs539268917 1441 dbSNP
rs1203477520 1448 dbSNP
rs934276663 1451 dbSNP
rs1275224871 1458 dbSNP
rs1175064505 1469 dbSNP
rs183789727 1470 dbSNP
rs868710182 1471 dbSNP
rs1444678959 1475 dbSNP
rs1225958840 1477 dbSNP
rs919779036 1483 dbSNP
rs1298107955 1484 dbSNP
rs931120241 1490 dbSNP
rs1397207491 1507 dbSNP
rs1044189454 1508 dbSNP
rs905313096 1513 dbSNP
rs1002285122 1515 dbSNP
rs1416511112 1518 dbSNP
rs1329334185 1530 dbSNP
rs1038436924 1535 dbSNP
rs1356013029 1543 dbSNP
rs1420360549 1547 dbSNP
rs1440356680 1547 dbSNP
rs1056874942 1559 dbSNP
rs574309032 1562 dbSNP
rs1308764243 1567 dbSNP
rs753060006 1568 dbSNP
rs1437571256 1576 dbSNP
rs1285433271 1587 dbSNP
rs552778980 1588 dbSNP
rs1248244244 1595 dbSNP
rs1214552248 1602 dbSNP
rs1468252188 1617 dbSNP
rs1010249393 1618 dbSNP
rs541234202 1620 dbSNP
rs756579697 1625 dbSNP
rs968274512 1630 dbSNP
rs1487318339 1638 dbSNP
rs560007390 1645 dbSNP
rs528845080 1662 dbSNP
rs188041379 1678 dbSNP
rs1056905378 1680 dbSNP
rs78886123 1684 dbSNP
rs144963125 1686 dbSNP
rs1304699922 1693 dbSNP
rs1440642815 1694 dbSNP
rs1202051045 1699 dbSNP
rs1237179106 1701 dbSNP
rs953967005 1702 dbSNP
rs1454844339 1706 dbSNP
rs1444806893 1719 dbSNP
rs562106503 1722 dbSNP
rs1158253242 1723 dbSNP
rs1417860704 1724 dbSNP
rs1382812220 1730 dbSNP
rs766963947 1736 dbSNP
rs1023528984 1737 dbSNP
rs986535098 1739 dbSNP
rs778359716 1743 dbSNP
rs530797018 1749 dbSNP
rs1188529554 1755 dbSNP
rs549091621 1762 dbSNP
rs1486217052 1763 dbSNP
rs1421443080 1769 dbSNP
rs1215066244 1774 dbSNP
rs191300384 1786 dbSNP
rs1330999216 1789 dbSNP
rs1407128040 1791 dbSNP
rs569875937 1792 dbSNP
rs975854195 1794 dbSNP
rs1339893951 1796 dbSNP
rs1298706146 1809 dbSNP
rs1383606203 1814 dbSNP
rs767811127 1818 dbSNP
rs528304305 1819 dbSNP
rs919873344 1829 dbSNP
rs931227546 1837 dbSNP
rs182462077 1840 dbSNP
rs1044242417 1849 dbSNP
rs1228851371 1851 dbSNP
rs927114914 1853 dbSNP
rs1417338144 1855 dbSNP
rs953017263 1858 dbSNP
rs1174221199 1860 dbSNP
rs189068356 1864 dbSNP
rs192387445 1866 dbSNP
rs184689209 1871 dbSNP
rs189059439 1874 dbSNP
rs191868186 1884 dbSNP
rs1433815251 1888 dbSNP
rs201414887 1894 dbSNP
rs1272399066 1902 dbSNP
rs985690878 1906 dbSNP
rs1429396841 1907 dbSNP
rs911452594 1907 dbSNP
rs1264072907 1913 dbSNP
rs941601719 1914 dbSNP
rs1191510896 1923 dbSNP
rs938097053 1924 dbSNP
rs1056526538 1926 dbSNP
rs1240781487 1928 dbSNP
rs974244352 1932 dbSNP
rs896489289 1943 dbSNP
rs1193898303 1951 dbSNP
rs546436434 1956 dbSNP
rs1042392030 1957 dbSNP
rs930051459 1960 dbSNP
rs1056518037 1961 dbSNP
rs752366021 1962 dbSNP
rs948011555 1974 dbSNP
rs1399780517 1975 dbSNP
rs74322730 1979 dbSNP
rs1462307840 1990 dbSNP
rs73950820 1991 dbSNP
rs903801472 1994 dbSNP
rs1028506137 1997 dbSNP
rs1000777299 2000 dbSNP
rs1031291215 2000 dbSNP
rs538168588 2001 dbSNP
rs1187863106 2003 dbSNP
rs1441255118 2004 dbSNP
rs1253305732 2010 dbSNP
rs538597010 2012 dbSNP
rs997684893 2015 dbSNP
rs1256977134 2016 dbSNP
rs772229048 2031 dbSNP
rs1451227377 2036 dbSNP
rs777258759 2041 dbSNP
rs969134549 2050 dbSNP
rs1293435650 2051 dbSNP
rs560106734 2060 dbSNP
rs1338559021 2069 dbSNP
rs557277802 2080 dbSNP
rs568900029 2081 dbSNP
rs1019333081 2084 dbSNP
rs1329519078 2085 dbSNP
rs985785680 2087 dbSNP
rs1395299341 2092 dbSNP
rs1164233954 2093 dbSNP
rs1471855281 2096 dbSNP
rs1015873064 2102 dbSNP
rs544232984 2105 dbSNP
rs140136828 2110 dbSNP
rs1284355682 2115 dbSNP
rs756717140 2120 dbSNP
rs376533219 2121 dbSNP
rs1026599682 2126 dbSNP
rs981819518 2127 dbSNP
rs1469484832 2141 dbSNP
rs1273429830 2148 dbSNP
rs80027060 2151 dbSNP
rs930130444 2153 dbSNP
rs35049164 2154 dbSNP
rs992670747 2168 dbSNP
rs1343745384 2172 dbSNP
rs979949411 2173 dbSNP
rs778915488 2174 dbSNP
rs1442854617 2181 dbSNP
rs186993039 2183 dbSNP
rs745744035 2185 dbSNP
rs1371917919 2187 dbSNP
rs1323180851 2189 dbSNP
rs1403629757 2196 dbSNP
rs772018691 2204 dbSNP
rs948105033 2213 dbSNP
rs1453759981 2214 dbSNP
rs993055410 2220 dbSNP
rs1045125837 2226 dbSNP
rs1487285552 2228 dbSNP
rs1192787616 2236 dbSNP
rs779957762 2249 dbSNP
rs1455004202 2251 dbSNP
rs1253185040 2252 dbSNP
rs918030034 2258 dbSNP
rs945442798 2259 dbSNP
rs903855083 2260 dbSNP
rs1285819584 2267 dbSNP
rs1205636892 2268 dbSNP
rs1352827820 2270 dbSNP
rs1236175680 2277 dbSNP
rs779046098 2277 dbSNP
rs1371490730 2280 dbSNP
rs936575320 2284 dbSNP
rs1434633922 2288 dbSNP
rs368810580 2289 dbSNP
rs572937544 2290 dbSNP
rs903824198 2294 dbSNP
rs892308992 2305 dbSNP
rs1197615759 2311 dbSNP
rs1435699261 2317 dbSNP
rs1394894442 2322 dbSNP
rs1171631737 2327 dbSNP
rs936912653 2329 dbSNP
rs1243505799 2333 dbSNP
rs1030562369 2336 dbSNP
rs888897357 2344 dbSNP
rs770107266 2349 dbSNP
rs1036288540 2351 dbSNP
rs1007259199 2361 dbSNP
rs889965246 2376 dbSNP
rs1160403280 2386 dbSNP
rs1348289630 2392 dbSNP
rs1277738311 2412 dbSNP
rs773290127 2418 dbSNP
rs745973308 2419 dbSNP
rs1008425309 2422 dbSNP
rs1020183872 2428 dbSNP
rs996173570 2430 dbSNP
rs1218036636 2431 dbSNP
rs1304250441 2435 dbSNP
rs1338579405 2436 dbSNP
rs1315314882 2440 dbSNP
rs1416005409 2444 dbSNP
rs1358929879 2447 dbSNP
rs541619490 2449 dbSNP
rs896942052 2450 dbSNP
rs1412008084 2458 dbSNP
rs553334390 2463 dbSNP
rs1025871016 2465 dbSNP
rs993843401 2476 dbSNP
rs1170980608 2477 dbSNP
rs578114878 2482 dbSNP
rs545410100 2486 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agacauUUAUAGGGAAACGGACu 5'
                ||| |    || |||| 
Target 5' aucaacAAUUUGGGCUU-CCUG- 3'
 		1 - 21
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000536142.1 | 3UTR | AUCAACAAUUUGGGCUUCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
70 hsa-miR-4742-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT065632 CLIC4 chloride intracellular channel 4 2 4
MIRT068170 TXLNA taxilin alpha 2 2
MIRT119024 TSN translin 2 2
MIRT165212 GRAMD3 GRAM domain containing 2B 2 2
MIRT175254 PSAT1 phosphoserine aminotransferase 1 2 4
MIRT213228 REST RE1 silencing transcription factor 2 6
MIRT296337 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT316776 FOXC1 forkhead box C1 2 2
MIRT453943 XRCC6 X-ray repair cross complementing 6 2 6
MIRT454599 RPL13A ribosomal protein L13a 2 2
MIRT458485 RMI1 RecQ mediated genome instability 1 2 6
MIRT458650 SGPP2 sphingosine-1-phosphate phosphatase 2 2 2
MIRT459240 ADRBK1 G protein-coupled receptor kinase 2 2 2
MIRT461008 SYT7 synaptotagmin 7 2 2
MIRT462026 RIF1 replication timing regulatory factor 1 2 2
MIRT462103 TMEM214 transmembrane protein 214 2 2
MIRT463255 ZIC5 Zic family member 5 2 4
MIRT465190 TRPS1 transcriptional repressor GATA binding 1 2 2
MIRT470507 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT472356 TSPAN1 tetraspanin 1 2 2
MIRT473260 MIDN midnolin 2 2
MIRT477527 EIF4G2 eukaryotic translation initiation factor 4 gamma 2 2 4
MIRT485182 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 4
MIRT486461 MDM2 MDM2 proto-oncogene 2 2
MIRT492760 PER1 period circadian clock 1 2 8
MIRT496703 TRIM39 tripartite motif containing 39 2 2
MIRT497227 MORC2 MORC family CW-type zinc finger 2 2 2
MIRT499582 INTU inturned planar cell polarity protein 2 4
MIRT504081 C9orf40 chromosome 9 open reading frame 40 2 6
MIRT505484 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT513255 FBXO17 F-box protein 17 2 2
MIRT525061 FRK fyn related Src family tyrosine kinase 2 2
MIRT528798 RAB32 RAB32, member RAS oncogene family 2 2
MIRT534357 SFT2D2 SFT2 domain containing 2 2 2
MIRT538731 CAPN1 calpain 1 2 2
MIRT550792 WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 2 2
MIRT553994 SRPR SRP receptor alpha subunit 2 4
MIRT568102 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT570107 SLC18B1 solute carrier family 18 member B1 2 2
MIRT570823 RPL7L1 ribosomal protein L7 like 1 2 2
MIRT572004 HMGB1 high mobility group box 1 2 2
MIRT572352 PCYT2 phosphate cytidylyltransferase 2, ethanolamine 2 2
MIRT609716 TMEM132C transmembrane protein 132C 2 2
MIRT613982 LRRC40 leucine rich repeat containing 40 2 2
MIRT620740 CCL16 C-C motif chemokine ligand 16 2 2
MIRT625074 C15orf41 chromosome 15 open reading frame 41 2 4
MIRT627941 NNT nicotinamide nucleotide transhydrogenase 2 2
MIRT629941 IGSF6 immunoglobulin superfamily member 6 2 2
MIRT633396 FBXW8 F-box and WD repeat domain containing 8 2 2
MIRT635846 ZNF264 zinc finger protein 264 2 2
MIRT638086 ZNF652 zinc finger protein 652 2 2
MIRT643996 TCHP trichoplein keratin filament binding 2 2
MIRT660020 C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2 2
MIRT660161 BRCC3 BRCA1/BRCA2-containing complex subunit 3 2 2
MIRT668887 CSRP1 cysteine and glycine rich protein 1 2 2
MIRT676729 METTL14 methyltransferase like 14 2 2
MIRT677210 MURC caveolae associated protein 4 2 2
MIRT685949 PTGIS prostaglandin I2 synthase 2 2
MIRT687816 ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein like 2 2 2
MIRT689900 SOD2 superoxide dismutase 2 2 2
MIRT698214 TMEM248 transmembrane protein 248 2 2
MIRT698279 TMEM2 transmembrane protein 2 2 2
MIRT698758 STK4 serine/threonine kinase 4 2 2
MIRT698789 STK38 serine/threonine kinase 38 2 2
MIRT703152 GPR137C G protein-coupled receptor 137C 2 2
MIRT704408 CTPS1 CTP synthase 1 2 2
MIRT705067 C4orf32 family with sequence similarity 241 member A 2 2
MIRT710201 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT714495 HSPA4 heat shock protein family A (Hsp70) member 4 2 2
MIRT720082 TNRC6B trinucleotide repeat containing 6B 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4742-5p Imatinib 5291 NSC743414 approved sensitive High Chronic Myelogenous Leukemia tissue
hsa-miR-4742-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4742-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-4742-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-4742-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4742-5p Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-4742-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-4742-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-4742-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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