miRTarBase - #MIRT120273


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pre-miRNA Information
pre-miRNA hsa-mir-1185-1   
Genomic Coordinates chr14: 101042977 - 101043062
Synonyms MIRN1185-1, hsa-mir-1185-1, MIR1185-1
Description Homo sapiens miR-1185-1 stem-loop
Comment This sequence was proposed as a miRNA candidate by Berezikov et al by RAKE analysis .
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-1185-1-3p
Sequence 53| AUAUACAGGGGGAGACUCUUAU |74
Evidence Not_experimental
Experiments
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 5 14 + 101043033 29233923 MiREDiBase
A-to-I 7 14 + 101043035 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs749794228 1 dbSNP
rs369414498 4 dbSNP
rs771096180 5 dbSNP
rs774958411 7 dbSNP
rs1226171972 11 dbSNP
rs1449899083 14 dbSNP
rs761183893 16 dbSNP
rs1380874583 20 dbSNP
rs771625921 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol GSK3B   
Synonyms -
Description glycogen synthase kinase 3 beta
Transcript NM_001146156   
Other Transcripts NM_002093   
Expression
Putative miRNA Targets on GSK3B
3'UTR of GSK3B
(miRNA target sites are highlighted)		 
>GSK3B|NM_001146156|3'UTR
   1 ACAGTCCCGAGCAGCCAGCTGCACAGGAAAAACCACCAGTTACTTGAGTGTCACTCAGCAACACTGGTCACGTTTGGAAA
  81 GAATATTAAAAAGAGAAAAAAATCCTGTTCATTTTAGTGTTCAATTTTTTTATTATTATTGTTGTTCTTATTTAACCTTG
 161 TAAAATATCTATAAATACAAACCAATTTCATTGTATTCTCACTTTGAGGGAGATCCAGGGGGTGGGAGGGGTTGTGGGGA
 241 GGGGGAAAGCGGAGCACTAGAACATACAATCTCTCTCCCACGACAATCTTTTTTTATTAAAAGTCTGCTGTTGTATACTT
 321 TAAAAACAGGACTCCTGCCTCATGCCCCTTCCACAAAAGAAGAAAACCTTTTTCTGTGCTGATGGGTTTTTTTGAACTTT
 401 GTTTTCTTTTAAAGTCTAGTGTGAGACTTTGGTATAGTGCACAGCTTGAAATTGGTTGGGAGCTTAGCAGGTATAACTCA
 481 ACGGGGACTTAAATGTCACTTGTAAAATTAATCCATATCTTCGGGTATTTATAGACTTGCCTTTGGCATGTTGGTGGCAG
 561 GTGTGGCAGACAAAGAAATGTGTATCATTCGTAACCCAGGGAGGTCAATAAAGTTTGGAACTCTACAGGGAAGATTCTTA
 641 GTAGATTTGTTAAGGTTTTGTTTTGCTCTCAGTTAGTGCTAGTGATGTAGAGGCTTGTACAGGAGGCTGCCAGAGGGGAA
 721 GCAGCAAGCAAGACTCAGGCACACATGCTCTACAGGTGGCTCTTTGTTTGCCTGACCAAAGTTCTTTGCAAATCTTAGCA
 801 CAGTTTCAAACTAGTGACCTGGGAGGAGATGGAAGGGGTGTTGAGCAGGCTGAGCTAGCTGCTGAGGTCAAAGGCTGATG
 881 AGCCCAGAGGAAGGGGACAGGTCAGGGATACATCTCACCACTGTGAATAAGTTTGTCCAGATTTTTTTCTAAAGTTACTT
 961 CCCTTGGAAAGATACACTTGAGAGGACATTGTAGTTAAATAATGTGAACTGTAACAGTCATCTACTGGTTTATTTTTCAT
1041 ATTTTTTAATTGAAAATTGAGCTTGCAGAAATAGCCACATTCTACACATAGTTCTAATTTTAAATCCAAATCTAGAATCT
1121 GTATTTAATTTGTTTTTTAACCTCATGCTTTTTACATTTATTTATTGATGCATGTCAGATGGTAGAAATATTAAAAACTA
1201 CACATCAGAATGATACAGTCACTTATACCTGCTGACTTTATAGGAAAGCTGATGATATAAATGTGTGTATATATGTTATA
1281 TATACATATATTCAATACTGCCTTTTTTTTTGTCTACAGTATCAAAATTGACTGGTTGAAGCATGAGAAGAATGTTTCCC
1361 CCACACCCAGTTAAGAGTTTTTGTGTCTGTTTTCTTTGTGTATCAGTGAACGATGTTAAGAATCAGTCTCTCTTTTTGAA
1441 GAAAAAGCAATATTCCTTGGAAAGCAAGGAGAATTGAAGGACTATGTTTGCCGTGAGGAAATAGATTTTCATGACTAGTT
1521 TGTTTTATACTTTTAAGGTTGGCATCTATGTGGGCCTTATATACTCTAAAATGAACTTTAGTCACCTTGGTGCTTATGGG
1601 CCATTACTTGACCTATGAATCTTTAAGGCACAATCAGTTGTACTTTACATTTAAAGATCACTTGAGTGATGGCCGCCTTT
1681 CCCTCCTACCCGCTCCTTCCCCACATGCCTTCCAAGGTTAGCTGGTAACTGTAGGGCTGCAGAGCTGAGCCCATGGTTGT
1761 GTGTAACTTGCCCTCACCCTCCTCATTGCCACCTTAGGTCACTTTATGGGTCTCGTCCTCCAGAGGGTTCGGAAGTGGAG
1841 TCTGTTGGCAGCCCTCCTGCAGGCCCTAGCACCCTGTCCTGCTCCTTAACTGTGTGTGTGACTCTCCAAGAGAGTTGTCC
1921 TGCCTGCTGAAGTGAACCAGTACCCAGAAAGACAACTGTGAGCCATCTTGGTTTTCACTCGCTGTTTAGCTGAGGTCTTG
2001 GGCCACAAAAGGGGTTTCACAAACCTCTGGATATATCAGAGTTTATGAGAAAGGAAACATGCTCAGTCAAACCAAATCAA
2081 ACAAATTGAATTTTATGTTTTATAAAGTGCTTCTGAAAGCTAAGATTTGAAAGAAGTCTGAAATCAAAGTATTTGGCAGC
2161 ATAACTCCTTAAAGGTAGTGGCGTTGATAGACCATTTTCAGACAGAATTTATAAAGAATCTGAAAAGGCAGGTCTGTGAT
2241 AGAGAAATGGACCTGCATTCAGATCCAACTGCCCAGCAAGCGTTTGGATGCAGACACTGCTCTGGACGTGGTATACTCCC
2321 CAGAGTCCATAAAAATCAGTGCTTATTTTAGGAAACAGGTTGCCCCCCACAACTGGGGTAAAAGAAGAGAGAAAAGTCAC
2401 GCTTTTCTCTCATTTCATTGTGTGTGCATGTGTGCGTGTGTGTGTGTGTGTGTGTGTGCTGAGATGTGTGATTTTTCTTT
2481 CTCAAGGATCATGGTGGGATCACAGAACTCTTTTATACAAGTGAGATCCAGGTCTCTGAATATCTTTTTGTATATAATAA
2561 TAATAAAAAGCTCCTCACCAAATTCAAGCTTGTACATTATATTTTCTTTCTGTGTTTTTAAATTTAAGTTTTATTGTTTT
2641 GTATGTAAATATGTGGACCCAGGAACTGTTATTAATGAGCAAAAAGTTACTGTTCAGGGCAGTGATTCTGTTTAATAATC
2721 AGACAAAATGTAGACGAGCTTTTTAAAGCCATATAGTTTTAACTCTGTACAGTAGGTACCGGCCTGTATTATTGTAACAA
2801 TAACTCTAGCAATGTATAGTGTATCTATATAGTTTGGAGTGCCTTCGCTTCCATGTGTTTTTTTTTTTAATTTGTTCTTT
2881 TTTAAATTTTAATTGGTTTCCTTTATCCATGTCTCCCTGTCCACCCCCTTTCCCTTTGAAATAATAACTCACTCATAACA
2961 GTATCTTTGCCCCTTCCACAGTTAAGTTTCAGTGATACCATACTCAGGAGTGGGAAGAGGAAATCATATTCGTAATTTCA
3041 TTTCGTTGAAGCCCTGCCTTTGTTTTGGTTCTGAATGTCTTTCCTCCTCGGTAGCAGTGAGACCGGTTTCATTTCATACT
3121 TAGTCCATTCAGGGACTTAGTGTAGCACCAGGGAGCCCTAGAGCTGGAGGATATCGAATAGATTAAATTTTGCTCGTCTC
3201 TTCCACAAGCCCTAACCATGGGTCTTAAAAACAGCAGATTCTGGGAGCCTTCCATGCTCTCTCTCTCTCCTCTTTTATCT
3281 ACTTCCCTCCCAAATGAGAGAGTGACAGAGAATTGTTTTTTTATAAATCGAAGTTTCTTAATAGTATCAGGTTTTGATAC
3361 GTCAGTGGTCTAAAATGCTATAGTGCAATTACTAGCAGTTACTGCACGGAGTGCCACCGTGCCAATAGAGGACTGTTGTT
3441 TTAACAAGGGAACTCTTAGCCCATTTCCTCCCTCCCGCCATCTCTACCCTTGCTCAATGAAATATCATTTTAATTTCTTT
3521 TAAAAAAAATCAGTTTAATTCTTACTGTGTGCCCAACACGAAGGCCTTTTTTGAAAGAAAAATAGAATGTTTTGCCTCAA
3601 AGTAGTCCATATAAAATGTCTTGAATAGAAGAAAAAACTACCAAACCAAAGGTTACTATTTTTGAAACATCGTGTGTTCA
3681 TTCCAGCAAGGCAGAAGACTGCACCTTCTTTCCAGTGACATGCTGTGTCATTTTTTTTAAGTCCTCTTAATTTTTAGACA
3761 CATTTTTGGTTTATGTTTTAACAATGTATGCCTAACCAGTCATCTTGTCTGCACCAATGCAAAGGTTTCTGAGAGGAGTA
3841 TTCTCTATCCCTGTGGATATGAAGACACTGGCATTTCATCTATTTTTCCCTTTCCTTTTTAAAGGATTTAACTTTGGAAT
3921 CTTCCAAAGGAAGTTTGGCCAATGCCAGATCCCCAGGAATTTGGGGGGTTTTCTTTCTTTTCAACTGAAATTGTATCTGA
4001 TTCCTACTGTTCATGTTAGTGATCATCTAATCACAGAGCCAAACACTTTTCTCCCCTGTGTGGAAAAGTAGGTATGCTTT
4081 ACAATAAAATCTGTCTTTTCTGGTAGAAACCTGAGCCACTGAAAATAAAAGAGACAACTAGAAGCACAGTAGAGTCCCAG
4161 ACTGAGATCTACCTTTGAGAGGCTTTGAAAGTAATCCCTGGGGTTTGGATTATTTTCACAAGGGTTATGCCGTTTTATTC
4241 AAGTTTGTTGCTCCGTTTTGCACCTCTGCAATAAAAGCAAAATGACAACCAGTACATAAGGGGTTAGCTTGACAAAGTAG
4321 ACTTCCTTGTGTTAATTTTTAAGTTTTTTTTTCCTTAACTATATCTGTCTACAGGCAGATACAGATAGTTGTATGAAAAT
4401 CTGCTTGCCTGTAAAATTTGCATTTATAAATGTGTTGCCGATGGATCACTTGGGCCTGTACACATACCAATTAGCGTGAC
4481 CACTTCCATCTTAAAAACAAACCTAAAAAACAAAATTTATTATATATATATATATATATATATAAAGGACTGTGGGTTGT
4561 ATACAAACTATTGCAAACACTTGTGCAAATCTGTCTTGATATAAAGGAAAAGCAAAATCTGTATAACATTATTACTACTT
4641 GAATGCCTCTGTGACTGATTTTTTTTTCATTTTAAATATAAACTTTTTTGTGAAAAGTATGCTCAATGTTTTTTTTCCCT
4721 TTCCCCATTCCCTTGTAAATACATTTTGTTCTATGTGACTTGGTTTGGAAATAGTTAACTGGTACTGTAATTTGCATTAA
4801 ATAAAAAGTAGGTTAGCCTGGAAATGAAATTAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uaUUCUCAGAGGGGGACAUAUa 5'
            || ||||| |: :|||||| 
Target 5' ttAAAAGTCTGCTGTTGTATAc 3'
 297 - 318 156.00 -15.30
2 
miRNA  3' uauuCUCAGAGGGGGACAUAUa 5'
              || | ||::::|||||| 
Target 5' ctctGAATATCTTTTTGTATAt 3'
 2534 - 2555 146.00 -11.40
3 
miRNA  3' uaUUCUCAGAGGGGGACAUAUa 5'
            || || |    :||||||| 
Target 5' ggAAAAG-CAAAATCTGTATAa 3'
 4606 - 4626 143.00 -7.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN28189251 9 COSMIC
COSN30190554 11 COSMIC
COSN31548162 19 COSMIC
COSN30112696 28 COSMIC
COSN26641828 64 COSMIC
COSN30118885 64 COSMIC
COSN30484908 83 COSMIC
COSN30519701 103 COSMIC
COSN30468642 110 COSMIC
COSN28868342 125 COSMIC
COSN15647183 129 COSMIC
COSN30698971 135 COSMIC
COSN31558049 165 COSMIC
COSN27929410 176 COSMIC
COSN6747284 322 COSMIC
COSN15097152 453 COSMIC
COSN17459376 757 COSMIC
COSN21000745 1028 COSMIC
COSN25388968 1119 COSMIC
COSN22847658 1215 COSMIC
COSN23846056 1671 COSMIC
COSN32056193 1784 COSMIC
COSN7814300 1960 COSMIC
COSN9233524 2239 COSMIC
COSN18723319 2439 COSMIC
COSN20098922 2626 COSMIC
COSN5865392 3014 COSMIC
COSN1910508 3121 COSMIC
COSN32176438 3130 COSMIC
COSN1910507 3174 COSMIC
COSN1910505 3512 COSMIC
COSN28365366 3521 COSMIC
COSN17212328 3531 COSMIC
COSN1910503 3678 COSMIC
COSN29533445 3730 COSMIC
COSN14935032 4001 COSMIC
COSN31962129 4254 COSMIC
COSN21514816 4284 COSMIC
COSN9233523 4352 COSMIC
COSN23364212 4543 COSMIC
COSN20098917 4658 COSMIC
COSN5518849 4778 COSMIC
COSN16377125 4939 COSMIC
COSN21734641 4958 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs141641235 2 dbSNP
rs1232892264 4 dbSNP
rs546174832 7 dbSNP
rs748262855 8 dbSNP
rs202040450 9 dbSNP
rs750209798 10 dbSNP
rs1315979333 12 dbSNP
rs1239441454 21 dbSNP
rs199546717 30 dbSNP
rs1426594445 36 dbSNP
rs968330945 38 dbSNP
rs542318284 44 dbSNP
rs751072793 45 dbSNP
rs907210559 49 dbSNP
rs1390278102 51 dbSNP
rs758941856 51 dbSNP
rs1382937924 58 dbSNP
rs767709239 65 dbSNP
rs763534104 71 dbSNP
rs762507594 72 dbSNP
rs897255086 85 dbSNP
rs199859509 89 dbSNP
rs1336099921 93 dbSNP
rs1468704511 95 dbSNP
rs1296737385 96 dbSNP
rs201590431 102 dbSNP
rs1360153357 103 dbSNP
rs746458626 103 dbSNP
rs759870561 103 dbSNP
rs941898738 104 dbSNP
rs1447980133 105 dbSNP
rs1257411907 106 dbSNP
rs777008186 107 dbSNP
rs200620630 110 dbSNP
rs887662264 117 dbSNP
rs530691026 123 dbSNP
rs761198888 124 dbSNP
rs72548714 129 dbSNP
rs779447242 132 dbSNP
rs1432607920 135 dbSNP
rs1340919293 138 dbSNP
rs931622469 140 dbSNP
rs72548715 141 dbSNP
rs750133756 152 dbSNP
rs1377288278 162 dbSNP
rs1334902414 164 dbSNP
rs1409521986 168 dbSNP
rs772335906 169 dbSNP
rs748255898 171 dbSNP
rs779051945 172 dbSNP
rs1417638176 176 dbSNP
rs1186349448 181 dbSNP
rs774629070 183 dbSNP
rs769024453 185 dbSNP
rs1210203907 186 dbSNP
rs1457219144 187 dbSNP
rs1432626259 188 dbSNP
rs756786679 191 dbSNP
rs1027590991 198 dbSNP
rs1436764558 199 dbSNP
rs1319705741 204 dbSNP
rs370966100 208 dbSNP
rs1166211536 214 dbSNP
rs1383270104 216 dbSNP
rs536026067 219 dbSNP
rs1249281793 220 dbSNP
rs577837728 222 dbSNP
rs1239195305 223 dbSNP
rs1262092989 224 dbSNP
rs1459070527 226 dbSNP
rs1208481660 227 dbSNP
rs753236238 228 dbSNP
rs1462942748 230 dbSNP
rs1180586188 235 dbSNP
rs913594829 239 dbSNP
rs1250867728 241 dbSNP
rs553338622 243 dbSNP
rs541401765 250 dbSNP
rs574103832 251 dbSNP
rs1034564302 254 dbSNP
rs1177424856 259 dbSNP
rs72548716 267 dbSNP
rs72548717 269 dbSNP
rs570170452 271 dbSNP
rs994198711 273 dbSNP
rs946690282 277 dbSNP
rs1017438369 280 dbSNP
rs1227330369 281 dbSNP
rs921842453 282 dbSNP
rs1283566609 285 dbSNP
rs558063028 286 dbSNP
rs887620870 291 dbSNP
rs966259734 295 dbSNP
rs1481278170 296 dbSNP
rs911699500 296 dbSNP
rs1050283416 298 dbSNP
rs983521021 306 dbSNP
rs1472323483 309 dbSNP
rs1200344952 315 dbSNP
rs950760740 321 dbSNP
rs1434654079 334 dbSNP
rs868705055 339 dbSNP
rs1390918153 342 dbSNP
rs901797779 344 dbSNP
rs1358495778 348 dbSNP
rs1294914944 351 dbSNP
rs1040006244 354 dbSNP
rs1451245650 355 dbSNP
rs550455934 356 dbSNP
rs1299824233 357 dbSNP
rs4331700 362 dbSNP
rs1368120174 367 dbSNP
rs945740914 380 dbSNP
rs1027622043 381 dbSNP
rs866818344 382 dbSNP
rs372065817 386 dbSNP
rs566210911 391 dbSNP
rs1300945732 398 dbSNP
rs1023621563 402 dbSNP
rs746478791 411 dbSNP
rs1273131528 416 dbSNP
rs777401016 417 dbSNP
rs66753817 418 dbSNP
rs999283883 426 dbSNP
rs186981433 437 dbSNP
rs1487662636 438 dbSNP
rs1190843140 451 dbSNP
rs778799438 454 dbSNP
rs1244087524 455 dbSNP
rs1428936615 462 dbSNP
rs1170361721 471 dbSNP
rs1269272927 477 dbSNP
rs1428506951 482 dbSNP
rs68194015 483 dbSNP
rs67881446 485 dbSNP
rs67889588 486 dbSNP
rs1292612173 493 dbSNP
rs1363033967 494 dbSNP
rs753706144 495 dbSNP
rs1217464059 506 dbSNP
rs1384323833 511 dbSNP
rs372898074 511 dbSNP
rs111356766 513 dbSNP
rs527817915 514 dbSNP
rs911727101 515 dbSNP
rs1246789218 522 dbSNP
rs983217098 523 dbSNP
rs929429164 525 dbSNP
rs1376763132 532 dbSNP
rs1221063529 544 dbSNP
rs1242942073 549 dbSNP
rs920678672 558 dbSNP
rs1486060781 579 dbSNP
rs1006069835 585 dbSNP
rs1246099167 586 dbSNP
rs375571367 587 dbSNP
rs973453267 590 dbSNP
rs970451838 591 dbSNP
rs1022937900 595 dbSNP
rs1164134038 601 dbSNP
rs1327216598 604 dbSNP
rs993505352 606 dbSNP
rs779834006 607 dbSNP
rs1403118372 609 dbSNP
rs954181112 622 dbSNP
rs1380133490 630 dbSNP
rs4331699 633 dbSNP
rs1028771676 634 dbSNP
rs1031878250 638 dbSNP
rs756130454 639 dbSNP
rs1364944772 645 dbSNP
rs562910651 649 dbSNP
rs1298213514 651 dbSNP
rs543387816 654 dbSNP
rs565055074 666 dbSNP
rs1373163484 670 dbSNP
rs1171913652 678 dbSNP
rs750461865 683 dbSNP
rs1009869521 687 dbSNP
rs927702542 697 dbSNP
rs181105632 700 dbSNP
rs1379121009 715 dbSNP
rs551271791 718 dbSNP
rs980568648 719 dbSNP
rs1184071630 732 dbSNP
rs1190797666 734 dbSNP
rs1239186703 735 dbSNP
rs935730842 740 dbSNP
rs927057141 745 dbSNP
rs1022449010 749 dbSNP
rs969264980 750 dbSNP
rs72548718 752 dbSNP
rs1262755799 753 dbSNP
rs1194390787 757 dbSNP
rs1458437081 762 dbSNP
rs900182872 773 dbSNP
rs1038656469 774 dbSNP
rs1489307696 775 dbSNP
rs1278352851 777 dbSNP
rs917471646 778 dbSNP
rs944636252 784 dbSNP
rs1296083699 788 dbSNP
rs1346369460 792 dbSNP
rs559658169 793 dbSNP
rs1357971194 798 dbSNP
rs973409477 801 dbSNP
rs1447388765 803 dbSNP
rs1280150501 810 dbSNP
rs773372138 817 dbSNP
rs890366617 825 dbSNP
rs1258087320 829 dbSNP
rs761963731 830 dbSNP
rs1204106059 838 dbSNP
rs961378767 844 dbSNP
rs188729062 845 dbSNP
rs1209353277 855 dbSNP
rs1278438875 856 dbSNP
rs751805152 863 dbSNP
rs929124991 864 dbSNP
rs984168678 869 dbSNP
rs148679423 871 dbSNP
rs973910428 872 dbSNP
rs764405097 876 dbSNP
rs183675338 877 dbSNP
rs915900379 880 dbSNP
rs1414331690 883 dbSNP
rs965857168 886 dbSNP
rs77368793 895 dbSNP
rs1408128078 896 dbSNP
rs1010587753 897 dbSNP
rs1346461995 907 dbSNP
rs1233686451 916 dbSNP
rs891734411 932 dbSNP
rs1424155387 933 dbSNP
rs1218535837 935 dbSNP
rs1273656642 947 dbSNP
rs1194636756 949 dbSNP
rs960316954 951 dbSNP
rs1478950799 954 dbSNP
rs1031909329 955 dbSNP
rs1186965017 976 dbSNP
rs1443442682 980 dbSNP
rs977613655 984 dbSNP
rs968886011 990 dbSNP
rs1376239101 991 dbSNP
rs2037547 1020 dbSNP
rs1317671379 1022 dbSNP
rs180780479 1024 dbSNP
rs189300766 1030 dbSNP
rs1220053954 1036 dbSNP
rs1427897627 1039 dbSNP
rs75575079 1040 dbSNP
rs1366286606 1043 dbSNP
rs950169610 1048 dbSNP
rs879149084 1050 dbSNP
rs1017724631 1072 dbSNP
rs760157379 1078 dbSNP
rs890397598 1085 dbSNP
rs1329089477 1091 dbSNP
rs539619910 1104 dbSNP
rs1047626466 1114 dbSNP
rs1298208268 1117 dbSNP
rs572310715 1121 dbSNP
rs1273215083 1123 dbSNP
rs1446017332 1126 dbSNP
rs1400727540 1127 dbSNP
rs910172421 1129 dbSNP
rs762910410 1132 dbSNP
rs1194422394 1134 dbSNP
rs79610052 1136 dbSNP
rs1448139754 1138 dbSNP
rs1411918304 1139 dbSNP
rs921311163 1142 dbSNP
rs976817421 1144 dbSNP
rs1459531554 1158 dbSNP
rs867184088 1159 dbSNP
rs1037501386 1164 dbSNP
rs1390341164 1167 dbSNP
rs1473165592 1170 dbSNP
rs772531912 1176 dbSNP
rs1370333760 1177 dbSNP
rs185646830 1178 dbSNP
rs1296806466 1180 dbSNP
rs915994879 1187 dbSNP
rs1019174195 1194 dbSNP
rs1246395054 1201 dbSNP
rs988689229 1202 dbSNP
rs562504663 1203 dbSNP
rs1032968794 1204 dbSNP
rs1270337116 1205 dbSNP
rs1463848362 1206 dbSNP
rs774114917 1208 dbSNP
rs1244349745 1216 dbSNP
rs1425601258 1218 dbSNP
rs905540719 1222 dbSNP
rs568461110 1226 dbSNP
rs924576839 1227 dbSNP
rs977685655 1232 dbSNP
rs746961563 1239 dbSNP
rs1022698559 1240 dbSNP
rs1390497199 1252 dbSNP
rs1013995732 1254 dbSNP
rs914730648 1258 dbSNP
rs1319768419 1265 dbSNP
rs1402904487 1282 dbSNP
rs895596547 1283 dbSNP
rs1309886008 1286 dbSNP
rs112822116 1295 dbSNP
rs1228580704 1297 dbSNP
rs548548313 1298 dbSNP
rs1466815300 1303 dbSNP
rs1289858366 1305 dbSNP
rs975602388 1307 dbSNP
rs1327497099 1311 dbSNP
rs150696846 1312 dbSNP
rs199790427 1312 dbSNP
rs964859621 1312 dbSNP
rs940244202 1314 dbSNP
rs1228594763 1316 dbSNP
rs888659172 1316 dbSNP
rs1357831465 1319 dbSNP
rs1277309849 1320 dbSNP
rs1239294234 1321 dbSNP
rs1017292182 1329 dbSNP
rs144189446 1332 dbSNP
rs954392403 1333 dbSNP
rs1025914238 1348 dbSNP
rs1438450460 1360 dbSNP
rs993378810 1373 dbSNP
rs1301046355 1374 dbSNP
rs1400816518 1376 dbSNP
rs149350172 1383 dbSNP
rs370827005 1390 dbSNP
rs1323128683 1394 dbSNP
rs1309439448 1402 dbSNP
rs1406223348 1411 dbSNP
rs1037978129 1412 dbSNP
rs1012734252 1413 dbSNP
rs1314317953 1415 dbSNP
rs1231663590 1429 dbSNP
rs542954663 1433 dbSNP
rs1483402786 1436 dbSNP
rs1207461706 1442 dbSNP
rs749019183 1450 dbSNP
rs944112240 1452 dbSNP
rs1156965026 1453 dbSNP
rs1267738455 1455 dbSNP
rs1434710367 1459 dbSNP
rs1439569128 1460 dbSNP
rs914023080 1466 dbSNP
rs532936566 1467 dbSNP
rs989048281 1480 dbSNP
rs938723510 1484 dbSNP
rs1180827661 1486 dbSNP
rs1408773193 1486 dbSNP
rs73175828 1491 dbSNP
rs1370124867 1492 dbSNP
rs1041704196 1493 dbSNP
rs1221814074 1498 dbSNP
rs1453008925 1501 dbSNP
rs1301179338 1527 dbSNP
rs947658729 1530 dbSNP
rs1231271652 1544 dbSNP
rs745533289 1545 dbSNP
rs1215280367 1546 dbSNP
rs1272482507 1550 dbSNP
rs1354249340 1560 dbSNP
rs1311369811 1561 dbSNP
rs914829801 1579 dbSNP
rs1222520276 1585 dbSNP
rs755934268 1586 dbSNP
rs1489322187 1587 dbSNP
rs978694516 1596 dbSNP
rs1366617832 1599 dbSNP
rs1252283099 1601 dbSNP
rs964232790 1603 dbSNP
rs912703467 1604 dbSNP
rs1437408182 1606 dbSNP
rs1387746253 1611 dbSNP
rs1351857693 1615 dbSNP
rs547650596 1617 dbSNP
rs1022626454 1624 dbSNP
rs529196619 1631 dbSNP
rs1456699018 1633 dbSNP
rs1013964355 1664 dbSNP
rs745829372 1674 dbSNP
rs1025945315 1675 dbSNP
rs1004753366 1685 dbSNP
rs781202840 1686 dbSNP
rs963649284 1691 dbSNP
rs1272241069 1692 dbSNP
rs1465209357 1693 dbSNP
rs561988591 1694 dbSNP
rs61570807 1701 dbSNP
rs1210463888 1705 dbSNP
rs888632569 1707 dbSNP
rs1048603042 1708 dbSNP
rs997034937 1709 dbSNP
rs1016168357 1713 dbSNP
rs34679567 1714 dbSNP
rs55910624 1714 dbSNP
rs1181992626 1716 dbSNP
rs1238758155 1719 dbSNP
rs1415347500 1728 dbSNP
rs1421620476 1731 dbSNP
rs1163798334 1733 dbSNP
rs1192167264 1734 dbSNP
rs894325640 1736 dbSNP
rs576408117 1747 dbSNP
rs1035481961 1748 dbSNP
rs1345188913 1761 dbSNP
rs1192574787 1767 dbSNP
rs756771200 1773 dbSNP
rs751682402 1777 dbSNP
rs764282374 1778 dbSNP
rs758704825 1783 dbSNP
rs1227920779 1784 dbSNP
rs944081264 1785 dbSNP
rs1207899572 1790 dbSNP
rs1002964087 1792 dbSNP
rs1052544865 1796 dbSNP
rs934466020 1797 dbSNP
rs1279011611 1805 dbSNP
rs1238659705 1806 dbSNP
rs903258848 1809 dbSNP
rs1220751209 1814 dbSNP
rs1041781236 1815 dbSNP
rs947394388 1818 dbSNP
rs1412306121 1822 dbSNP
rs1347545466 1825 dbSNP
rs893408743 1830 dbSNP
rs753000462 1831 dbSNP
rs1039970931 1835 dbSNP
rs942923784 1836 dbSNP
rs912734539 1840 dbSNP
rs978620991 1841 dbSNP
rs986895955 1851 dbSNP
rs915871337 1852 dbSNP
rs1352618699 1856 dbSNP
rs1226807409 1861 dbSNP
rs1286150311 1864 dbSNP
rs1349726162 1875 dbSNP
rs1219685288 1883 dbSNP
rs1341183063 1891 dbSNP
rs1300155412 1893 dbSNP
rs992457712 1894 dbSNP
rs1309901454 1896 dbSNP
rs1209613996 1898 dbSNP
rs562276586 1901 dbSNP
rs933106366 1913 dbSNP
rs1483799964 1921 dbSNP
rs564379157 1926 dbSNP
rs1177161874 1927 dbSNP
rs918988612 1950 dbSNP
rs1478575815 1955 dbSNP
rs1174810955 1971 dbSNP
rs1423736413 1976 dbSNP
rs972168294 1978 dbSNP
rs1434165047 1980 dbSNP
rs765640095 1981 dbSNP
rs1372487973 1982 dbSNP
rs138830070 1987 dbSNP
rs572247483 1990 dbSNP
rs1328458211 1992 dbSNP
rs1015728405 1997 dbSNP
rs145047652 1998 dbSNP
rs1436979655 1999 dbSNP
rs1003982390 2024 dbSNP
rs759904996 2034 dbSNP
rs1368771324 2037 dbSNP
rs952592464 2044 dbSNP
rs1027096315 2045 dbSNP
rs1343721905 2051 dbSNP
rs1016319346 2059 dbSNP
rs878917813 2062 dbSNP
rs1452523384 2065 dbSNP
rs1201555110 2078 dbSNP
rs1477967699 2082 dbSNP
rs193147776 2084 dbSNP
rs142829558 2099 dbSNP
rs188475324 2102 dbSNP
rs1427958941 2104 dbSNP
rs1167524355 2106 dbSNP
rs958576620 2109 dbSNP
rs1035554424 2120 dbSNP
rs1482853011 2121 dbSNP
rs536612926 2124 dbSNP
rs771322058 2134 dbSNP
rs1368531154 2141 dbSNP
rs1212233043 2142 dbSNP
rs900091559 2145 dbSNP
rs1366699808 2146 dbSNP
rs1224669046 2155 dbSNP
rs1269210906 2159 dbSNP
rs1002702170 2161 dbSNP
rs1041283447 2165 dbSNP
rs903294380 2166 dbSNP
rs1211283502 2178 dbSNP
rs567154860 2182 dbSNP
rs1008617259 2183 dbSNP
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rs138341826 2192 dbSNP
rs1052888843 2194 dbSNP
rs1447719915 2199 dbSNP
rs1012047372 2203 dbSNP
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rs1192650012 2207 dbSNP
rs893156029 2207 dbSNP
rs539508225 2208 dbSNP
rs1040072128 2218 dbSNP
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rs753331328 2228 dbSNP
rs1378625660 2234 dbSNP
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rs565824184 2251 dbSNP
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rs1390814879 2260 dbSNP
rs1380017832 2262 dbSNP
rs1316953222 2272 dbSNP
rs1340578206 2275 dbSNP
rs1303924820 2281 dbSNP
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rs767031216 2290 dbSNP
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rs150443898 2308 dbSNP
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rs1006843665 2695 dbSNP
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rs768185318 2735 dbSNP
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rs1421486437 2870 dbSNP
rs1305589981 2871 dbSNP
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rs1263897271 2993 dbSNP
rs1006900667 2995 dbSNP
rs1192718923 2997 dbSNP
rs1238324770 2998 dbSNP
rs1475409471 3000 dbSNP
rs955392340 3009 dbSNP
rs1166742450 3013 dbSNP
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rs1291770395 3081 dbSNP
rs568256672 3083 dbSNP
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rs924189952 3096 dbSNP
rs747082607 3104 dbSNP
rs549752275 3105 dbSNP
rs1281132055 3106 dbSNP
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rs1006113695 3118 dbSNP
rs1255082927 3119 dbSNP
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rs937052418 3174 dbSNP
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rs570682812 3198 dbSNP
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rs1171714363 3212 dbSNP
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rs1391277289 3269 dbSNP
rs1304855604 3270 dbSNP
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rs190976553 3303 dbSNP
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rs752980525 3311 dbSNP
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rs765472399 3313 dbSNP
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rs1325250601 3360 dbSNP
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rs934115114 3414 dbSNP
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rs1176016151 3654 dbSNP
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rs1404301817 3874 dbSNP
rs1318557789 3877 dbSNP
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rs1397763358 3889 dbSNP
rs983817609 3891 dbSNP
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rs1158581459 3993 dbSNP
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rs1386522605 4012 dbSNP
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rs755322116 4025 dbSNP
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rs775240907 4137 dbSNP
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rs1385786140 4795 dbSNP
rs1216827981 4796 dbSNP
rs1007488417 4804 dbSNP
rs889142950 4809 dbSNP
rs1185409223 4831 dbSNP
rs1422757338 4839 dbSNP
rs1473095268 4840 dbSNP
rs1437574953 4843 dbSNP
rs1164436801 4846 dbSNP
rs1052223268 4851 dbSNP
rs1237393595 4853 dbSNP
rs1404359674 4867 dbSNP
rs1298481501 4872 dbSNP
rs114683853 4878 dbSNP
rs1398607881 4882 dbSNP
rs1015497346 4883 dbSNP
rs189438302 4887 dbSNP
rs1341532436 4891 dbSNP
rs10610184 4895 dbSNP
rs1282470320 4897 dbSNP
rs1219471959 4902 dbSNP
rs1355794418 4904 dbSNP
rs576967305 4905 dbSNP
rs1288510602 4907 dbSNP
rs888304860 4909 dbSNP
rs1027198729 4915 dbSNP
rs1214110806 4921 dbSNP
rs558390082 4926 dbSNP
rs1375112364 4927 dbSNP
rs1306779051 4930 dbSNP
rs1442888828 4937 dbSNP
rs1189584768 4939 dbSNP
rs1366175743 4940 dbSNP
rs905275708 4942 dbSNP
rs1158869712 4943 dbSNP
rs937932950 4946 dbSNP
rs926294589 4948 dbSNP
rs540482814 4950 dbSNP
rs184362355 4951 dbSNP
rs1026488235 4953 dbSNP
rs1165370360 4959 dbSNP
rs1417827843 4962 dbSNP
rs1332837852 4965 dbSNP
rs182224920 4967 dbSNP
rs548154585 4970 dbSNP
rs746957637 4972 dbSNP
rs777660585 4974 dbSNP
rs772218614 4975 dbSNP
rs1311579132 4976 dbSNP
rs1419826298 4976 dbSNP
rs1252924230 4979 dbSNP
rs1189753579 4983 dbSNP
rs1239729741 4985 dbSNP
rs1259893574 4989 dbSNP
rs1490201817 4999 dbSNP
rs536282396 5001 dbSNP
rs936877302 5003 dbSNP
rs1254076219 5008 dbSNP
rs1460818907 5015 dbSNP
rs1178652876 5022 dbSNP
rs1016448270 5026 dbSNP
rs1437404073 5033 dbSNP
rs1157728377 5050 dbSNP
rs925484069 5057 dbSNP
rs986256394 5060 dbSNP
rs1378563420 5077 dbSNP
rs1007748294 5078 dbSNP
rs1171194203 5088 dbSNP
rs1402052787 5091 dbSNP
rs1466626526 5092 dbSNP
rs1333398070 5096 dbSNP
rs1374811840 5100 dbSNP
rs932445195 5107 dbSNP
rs558076099 5111 dbSNP
rs1331467491 5121 dbSNP
rs889395629 5123 dbSNP
rs147553154 5124 dbSNP
rs190451853 5132 dbSNP
rs997964646 5134 dbSNP
rs779171605 5140 dbSNP
rs1199238824 5142 dbSNP
rs976416858 5143 dbSNP
rs370672513 5147 dbSNP
rs1319172061 5149 dbSNP
rs1298716882 5159 dbSNP
rs1404005977 5160 dbSNP
rs752047117 5162 dbSNP
rs1197146425 5175 dbSNP
rs1429069475 5176 dbSNP
rs754246763 5185 dbSNP
rs79593583 5186 dbSNP
rs1478415241 5197 dbSNP
rs200221532 5197 dbSNP
rs1173510515 5204 dbSNP
rs780569631 5208 dbSNP
rs1345560158 5209 dbSNP
rs952730618 5216 dbSNP
rs756630621 5225 dbSNP
rs750988917 5227 dbSNP
rs1294198185 5230 dbSNP
rs1393072234 5236 dbSNP
rs1385332353 5237 dbSNP
rs763470280 5240 dbSNP
rs969489876 5243 dbSNP
rs1344696021 5245 dbSNP
rs1219155552 5254 dbSNP
rs1398015739 5255 dbSNP
rs865799411 5261 dbSNP
rs1025074952 5272 dbSNP
rs1013650555 5277 dbSNP
rs184240292 5284 dbSNP
rs1053646936 5289 dbSNP
rs150176560 5291 dbSNP
rs1375772995 5297 dbSNP
rs1478384973 5297 dbSNP
rs1174184581 5301 dbSNP
rs1480252381 5307 dbSNP
rs926569926 5318 dbSNP
rs547265005 5328 dbSNP
rs1428453926 5336 dbSNP
rs1165510518 5338 dbSNP
rs1280118837 5346 dbSNP
rs981764346 5348 dbSNP
rs1430019727 5349 dbSNP
rs892466454 5358 dbSNP
rs1293219022 5363 dbSNP
rs1201698088 5371 dbSNP
rs1400314529 5374 dbSNP
rs1487554167 5375 dbSNP
rs1261630027 5376 dbSNP
rs1206295819 5380 dbSNP
rs949082233 5388 dbSNP
rs918986597 5390 dbSNP
rs1254667521 5396 dbSNP
rs1323046803 5396 dbSNP
rs1290660435 5398 dbSNP
rs1488414188 5404 dbSNP
rs1219171824 5407 dbSNP
rs1466984473 5408 dbSNP
rs1222477430 5410 dbSNP
rs1261507696 5412 dbSNP
rs1485803934 5413 dbSNP
rs1052827926 5414 dbSNP
rs1201995586 5416 dbSNP
rs1284569249 5421 dbSNP
rs963122269 5422 dbSNP
rs1381090566 5426 dbSNP
rs1421780338 5431 dbSNP
rs58437717 5433 dbSNP
rs1343260626 5438 dbSNP
rs1429918210 5446 dbSNP
rs74319567 5455 dbSNP
rs200385798 5456 dbSNP
rs757072645 5456 dbSNP
rs1313750971 5457 dbSNP
rs57215349 5457 dbSNP
rs796627121 5457 dbSNP
rs1353912515 5462 dbSNP
rs1241911423 5464 dbSNP
rs1383898194 5467 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 2932.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000264235.8 | 3UTR | UAUAACAUUAUUACUACUUGAAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000264235.8 | 3UTR | UAUAACAUUAUUACUACUUGAAUGCCUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
114 hsa-miR-1185-1-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT066415 TBK1 TANK binding kinase 1 2 4
MIRT073567 NR2F2 nuclear receptor subfamily 2 group F member 2 2 2
MIRT074516 USP1 ubiquitin specific peptidase 1 2 4
MIRT080576 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 6
MIRT086539 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT086547 MOB4 MOB family member 4, phocein 2 2
MIRT088684 EML4 echinoderm microtubule associated protein like 4 2 4
MIRT090811 MBNL1 muscleblind like splicing regulator 1 2 4
MIRT095500 PURA purine rich element binding protein A 2 2
MIRT109530 KLHL15 kelch like family member 15 2 6
MIRT109807 ZFX zinc finger protein, X-linked 2 2
MIRT117888 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT120273 GSK3B glycogen synthase kinase 3 beta 2 4
MIRT149892 LDLR low density lipoprotein receptor 2 2
MIRT178475 LCOR ligand dependent nuclear receptor corepressor 2 4
MIRT193445 RORA RAR related orphan receptor A 2 2
MIRT198527 DSG2 desmoglein 2 2 2
MIRT226427 TP53INP1 tumor protein p53 inducible nuclear protein 1 2 2
MIRT227669 SET SET nuclear proto-oncogene 2 2
MIRT320405 HOXA9 homeobox A9 2 2
MIRT407774 MRPL35 mitochondrial ribosomal protein L35 2 2
MIRT439228 ZMIZ1 zinc finger MIZ-type containing 1 1 1
MIRT439312 VAT1L vesicle amine transport 1 like 1 1
MIRT439421 TMOD1 tropomodulin 1 1 1
MIRT439446 TMEM104 transmembrane protein 104 1 1
MIRT439524 STIM2 stromal interaction molecule 2 1 1
MIRT439612 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 1 1
MIRT439997 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 1
MIRT440017 PCSK1 proprotein convertase subtilisin/kexin type 1 1 1
MIRT440131 NCOA4 nuclear receptor coactivator 4 1 1
MIRT440311 LRRC1 leucine rich repeat containing 1 1 1
MIRT440475 IAPP islet amyloid polypeptide 1 1
MIRT440511 HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1 1
MIRT440617 FOXA2 forkhead box A2 1 1
MIRT440666 FBXL16 F-box and leucine rich repeat protein 16 1 1
MIRT440705 ERO1LB endoplasmic reticulum oxidoreductase 1 beta 1 1
MIRT441007 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 1 1
MIRT441018 CAND1 cullin associated and neddylation dissociated 1 1 1
MIRT441062 C1orf43 chromosome 1 open reading frame 43 1 1
MIRT441209 ARCN1 archain 1 1 1
MIRT449461 HAT1 histone acetyltransferase 1 2 2
MIRT467104 SRI sorcin 2 2
MIRT468060 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 10
MIRT468476 SESN3 sestrin 3 2 4
MIRT473533 MAX MYC associated factor X 2 2
MIRT473852 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT474711 KIF13A kinesin family member 13A 2 6
MIRT481665 ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2 2
MIRT485120 SF3B3 splicing factor 3b subunit 3 2 2
MIRT493055 MTFR1 mitochondrial fission regulator 1 2 2
MIRT504258 C1orf147 chromosome 1 open reading frame 147 2 4
MIRT504361 ARID1B AT-rich interaction domain 1B 2 4
MIRT505748 SENP1 SUMO1/sentrin specific peptidase 1 2 8
MIRT506298 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT508442 ZNF608 zinc finger protein 608 2 4
MIRT512782 COL4A3BP collagen type IV alpha 3 binding protein 2 2
MIRT520447 TSPAN2 tetraspanin 2 2 4
MIRT522133 NRBF2 nuclear receptor binding factor 2 2 6
MIRT522395 MYADM myeloid associated differentiation marker 2 4
MIRT523397 GRIK3 glutamate ionotropic receptor kainate type subunit 3 2 4
MIRT523938 E2F8 E2F transcription factor 8 2 4
MIRT524349 CREB1 cAMP responsive element binding protein 1 2 2
MIRT524711 BRMS1L breast cancer metastasis-suppressor 1 like 2 4
MIRT525134 ZNF256 zinc finger protein 256 2 2
MIRT525710 DCAF12L2 DDB1 and CUL4 associated factor 12 like 2 2 2
MIRT531264 PPIL3 peptidylprolyl isomerase like 3 2 2
MIRT538844 BTG1 BTG anti-proliferation factor 1 2 2
MIRT541366 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT542093 KCNK10 potassium two pore domain channel subfamily K member 10 2 6
MIRT543770 RBM12B RNA binding motif protein 12B 2 4
MIRT543940 NCOA7 nuclear receptor coactivator 7 2 2
MIRT545150 GABRG1 gamma-aminobutyric acid type A receptor gamma1 subunit 2 2
MIRT545842 ZNF264 zinc finger protein 264 2 4
MIRT548057 GOLGA7 golgin A7 2 2
MIRT549242 ATXN1L ataxin 1 like 2 4
MIRT551829 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 2
MIRT552484 ZNF136 zinc finger protein 136 2 2
MIRT553663 TGFBR2 transforming growth factor beta receptor 2 2 2
MIRT554988 RAB39B RAB39B, member RAS oncogene family 2 2
MIRT555760 PCTP phosphatidylcholine transfer protein 2 2
MIRT556923 IRF2BP2 interferon regulatory factor 2 binding protein 2 2 4
MIRT564991 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT566458 PGGT1B protein geranylgeranyltransferase type I subunit beta 2 2
MIRT566538 PANK3 pantothenate kinase 3 2 2
MIRT567732 DLX2 distal-less homeobox 2 2 2
MIRT570081 KANSL1L KAT8 regulatory NSL complex subunit 1 like 2 2
MIRT571735 RNF11 ring finger protein 11 2 2
MIRT573529 MDM2 MDM2 proto-oncogene 2 2
MIRT574459 RPS16 ribosomal protein S16 2 2
MIRT574992 Phka1 phosphorylase kinase alpha 1 2 3
MIRT576349 Pxdn peroxidasin 2 2
MIRT610196 CD99 CD99 molecule (Xg blood group) 2 4
MIRT612920 GPRIN3 GPRIN family member 3 2 2
MIRT615021 DUSP6 dual specificity phosphatase 6 2 2
MIRT623573 IRS1 insulin receptor substrate 1 2 2
MIRT624437 CASD1 CAS1 domain containing 1 2 2
MIRT628714 ZNF585A zinc finger protein 585A 2 2
MIRT639565 PCK1 phosphoenolpyruvate carboxykinase 1 2 4
MIRT641485 POLA2 DNA polymerase alpha 2, accessory subunit 2 2
MIRT641657 PAPOLG poly(A) polymerase gamma 2 2
MIRT642210 RUVBL2 RuvB like AAA ATPase 2 2 2
MIRT653010 STX7 syntaxin 7 2 2
MIRT656130 MSH6 mutS homolog 6 2 2
MIRT656893 KIAA2018 upstream transcription factor family member 3 2 2
MIRT660130 BRPF3 bromodomain and PHD finger containing 3 2 2
MIRT660855 AFAP1 actin filament associated protein 1 2 2
MIRT676843 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 3
MIRT681473 DIP2A disco interacting protein 2 homolog A 2 2
MIRT682253 RS1 retinoschisin 1 2 2
MIRT694296 COPB2 coatomer protein complex subunit beta 2 2 2
MIRT694401 ALDH1A3 aldehyde dehydrogenase 1 family member A3 2 2
MIRT705277 BACH1 BTB domain and CNC homolog 1 2 2
MIRT720833 C1orf52 chromosome 1 open reading frame 52 2 2
MIRT735713 SIRT1 sirtuin 1 2 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-1185-1 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-1185-1 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-1185-1-3p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-1185-1-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-1185-1-3p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-1185-1-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-1185-1-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-1185-1-3p Palbociclib 5330286 NSC758247 approved resistant cell line (T47D)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-1185-1-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-1185-1-3p Prednisone/Azathioprine/Methotrexate/Cyclophosphamide/Mycophenolate mofetil sensitive tissue (myasthenia gravis)
hsa-miR-1185-1-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-1185-1-3p Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-1185-1-3p Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-1185-1-3p Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-1185-1-3p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-1185-1-3p Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-1185-1-3p Gemcitabine 60750 NSC613327 approved resistant cell line (MDA-231)
hsa-miR-1185-1-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-1185-1-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved resistant cell line (TOV-112D)

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