miRTarBase - #MIRT126718


—
pre-miRNA Information
pre-miRNA hsa-mir-6733   
Genomic Coordinates chr1: 43171652 - 43171712
Description Homo sapiens miR-6733 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6733-5p
Sequence 6| UGGGAAAGACAAACUCAGAGUU |27
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs953882106 3 dbSNP
rs371499741 9 dbSNP
rs778441909 21 dbSNP
rs1348902205 22 dbSNP
Putative Targets

Gene Information
Gene Symbol WAC   
Synonyms BM-016, DESSH, PRO1741, Wwp4
Description WW domain containing adaptor with coiled-coil
Transcript NM_016628   
Other Transcripts NM_100486   
Expression
Putative miRNA Targets on WAC
3'UTR of WAC
(miRNA target sites are highlighted)		 
>WAC|NM_016628|3'UTR
   1 AGATGTGAATAATTGCACATGGTTTTGAGAACAGGAACTGTAAATCTGTTGCCCAATCTTAACATTTTTGAGCTGCATTT
  81 AAGTAGACTTTGGACCGTTAAGCTGGGCAAAGGAAATGACAAGGGGACGGGGTCTGTGAGAGTCAATTCAGGGGAAAGAT
 161 ACAAGATTGATTTGTAAAACCCTTGAAATGTAGATTTCTTGTAGATGTATCCTTCACGTTGTAAATATGTTTTGTAGAGT
 241 GAAGCCATGGGAAGCCATGTGTAACAGAGCTTAGACATCCAAAACTAATCAATGCTGAGGTGGCTAAATACCTAGCCTTT
 321 TACATGTAAACCTGTCTGCAAAATTAGCTTTTTTAAAAAAAAAAAAAAAAAAATTGGGGGGGTTAATTTATCATTCAGAA
 401 ATCTTGCATTTTCAAAAATTCAGTGCAAGCGCCAGGCGATTTGTGTCTAAGGATACGATTTTGAACCATATGGGCAGTGT
 481 ACAAAATATGAAACAACTGTTTCCACACTTGCACCTGATCAAGAGCAGTGCTTCTCCATTTGTTTTGCAGAGAAATGTTT
 561 TTCATTTCCCGTGTGTTTCCATTTCCTTCTGAAATTCTGATTTTATCCATTTTTTTAAGGCTCCTCTTTATCTCCTTTCT
 641 TAAGGCACTGTTGCTATGGCACTTTTCTATAACCTTTTCATTCCTGTGTACAGTAGCTTAAAATTGCAGTGATTGAGCAT
 721 AACCTACTTGTTTGTATAAATTATTGAAATCCATTTGCACCCTGTTAAGAATGGACTTAAAAGTACTGCTGGACAGGCAT
 801 GTGTGCTCAAAGTACATTGATTGCTCAAATATAAGGAAATGGCCCAATGAACGTGGTTGTGGGAGGGGAAAGAGGAAACA
 881 GAGCTAGTCAGATGTGAATTGTATCTGTTGTAATAAACATGTTAAAACAAACAAAAATTGTTATTTTTCTTTTCCTTCGG
 961 TCAGTGCACATTAGCATTTGAACTACCTGGGGATTCTTTATCAGAACTGTTCTTGTTGAATATTTATACTTAATTGAAAT
1041 AATTCCTTAAGGGAGGTTTTGTTTAAAACGTATTAACAGGAAATTGTGTATGAGATATTTAATGAAATAAGAAATTCAAC
1121 AAGAATGATTAAGTCACTTCCCAAGTGGTTGTCATTTGTTAAACCCTGGTTTACCTGTCTTGCTATTATGACATTTCATT
1201 TGGAAGGATGTTTGTGTTGTAGCTAACTGTTCAAGTCTGGTGCTGACTGCTGTTCTTAGCCATCACAAAACGCTAAATTT
1281 GTGTAATTGGAGCTTCCTGCTGTTATCTGGAAATAGCAGGAAAGCGCAGCTTTGTATATTGTTTCCTAAAGTATATTAAA
1361 ATAAAAAAAGAAACTATTGCTACTATAAAATTACCTTGACTTTTTTTTTCCTTTGCTGAAATATTAGTCACATAGCCTTA
1441 GCTTCACACTGCCAGTAATGTATCAAATCACAAGGGTTTCCGCATGAAAAAAATCTTTTCTTCCCCCACAAAAAAACCTT
1521 TACCATCAAAATCTTGCCATCTGATTTAGAAAGGTGTTTCTTCTTCTTCTTCTTTTTTTTCTTTAAATTGGTTTAGGGTT
1601 TTTTGGTGATTTTTTTTTTTTTTTTTTTTCTGTTGGGGCAGATAAGTGCTTCCAAAACTGGCAGCACCAAGGGCTTATTT
1681 TTTATGTTAGACATCAATGTCAATGTTACTACATTCTCGGATGCTAACATAAATTTTGAAATTGCTCTTGTGCTTTAAGC
1761 ATATATTGAAAGTATGGAAGTTAAATGTTCAGGCTTTTCAGTAAGCTCAAAAAGTTAACTGTAAGCGATAGTGTTGGTGT
1841 TTTCTAAAATACAAAAATGTTCCAGTGTAATTAAAAGGAATTAAAATCTTGAAGATATTTTCCTGTAATTTAAGGATACT
1921 TTTTAAATGTAAGAAAAGACATGTCATTAATTTATTGTCATGTTTATACCTCTGTGAGATTGTTAACATCTGCTGAATTT
2001 AACTAGTGCATGTAAATGAAACCCCAAAGAGCTGTGTGTTCAGCTAGAAACCTTACTGTATCTTTCCTGGAAAGAAGTGA
2081 GCAATTTGTTGTAATAGGCAAATGTTTCCTGATCAGATGGCAATTTGTGATTTAGGTAAATTTGAATTTGATTTGCTTAT
2161 AGTCTACTGGTCTGTGTACCTATGTTTTGTTTTTCAAAAAAGTTTACATCCCTAAATGAATTAGTCACATATATTTAGGA
2241 GAAGATGCCTAATTTGGTATTTCTTAATAGTGAATTTTTTTTTTTCTTGAGACAGAGTTTCACTCTTGTTGCCCAGGCTG
2321 GAGTGCAATGGCACGATCTCGGCTCACCGCAACCTCTGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCGGCGTTCCGAGT
2401 AGCTGGGATTACAGGCATGCACCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCA
2481 GGCTGGTCTTGAACTGCCAACTTCAGGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACC
2561 GCTCCTGGCCAGTAGTGAATTTTTAAACACAGAAAATCTAAAATTTTGTGGAAATATTTTAAATATTGCACCTTAATACA
2641 AGGTATCCAGCTCCTAACCTTAACTAGGGAATATCTATTAAAATAAGCATAATGTTCTGGACTAGAGTATTCCTTATCTA
2721 GTTGGTTATGGATTTGAACATGTACCTTGGTTTAGATACTTTGAAAATAGAAGTACTGAATAGCCTCTAGGGAACTTGAG
2801 TGGCCTTTCCCTCCCCCTGCCCCCCCCCCCCCCCCCCCGTTTTAAAAGATCAGTAGTCTCTATTCAAACTTTTAAAATGT
2881 CGTGGTATTGTAACAATATATTTGATGAAAGAAGGTTACAGACTCCCCTGAAGAACCAGCTTTCCTACGCTTTTTATTTT
2961 TCTAACTTGTCTAACCTGATTTTAAAATGACTGCAATTCCAGACTAAAAACATGCTTCAGCCCTGTTTCAAGACATTATG
3041 CTTCTTTTAACAGTCCAAATTAGTAGTTTTATTTTTCTTCTAAATCTTTGTTTCACACTTGTAAAATCTTGGGAAGGAGG
3121 TTCTTAAAACTTTGCCAGGAATTGTTACCCATTTCCAAAAACAGTTTATTATGTTCAAAAACCACCATATCTTTGAGGGA
3201 CTGTTTGAAAGGGGAGAGGGCAACGCGGGAAATAATTCACTCTGCGCACCGGAACTATTGTAGTTCAGGACTTCCAGCTA
3281 CTGTATTTAGATGTTGGGTTTGAATATACAGATTTCTTTTCAATACCTGTAAATATGGCTATATTCTTGTATTTGTACGG
3361 GAGTGTACAAAATGACACTGAAAAGTAATAAATATGTTTTGACTATATTGTGCAGTTATTTCAGAACTGTGTTTTGAAAG
3441 TCTTAGAATGCATAATTTGCATTTGAGTAAGGAAATTTAAAATACAGATTACTGCTGAGATTTTAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuGAGACUCAAACAGAAAGGGu 5'
            || |||| | | ||||||| 
Target 5' aaCT-TGAG-TGGCCTTTCCCt 3'
 2793 - 2812 158.00 -16.60
2 
miRNA  3' uuGAGACUCAAACAGAAAGGGu 5'
            :| | | ||| |||||:|| 
Target 5' aaTTGTTA-TTTTTCTTTTCCt 3'
 936 - 956 143.00 -9.20
3 
miRNA  3' uugaGACUCAAACAGAAAGGGu 5'
              || | | | |||||||: 
Target 5' aaacCTTACTGTATCTTTCCTg 3'
 2048 - 2069 142.00 -9.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1208240 168 ClinVar
COSN22119611 25 COSMIC
COSN30124259 97 COSMIC
COSN27814480 98 COSMIC
COSN31556576 105 COSMIC
COSN31517155 129 COSMIC
COSN23380500 209 COSMIC
COSN28250123 213 COSMIC
COSN30121410 262 COSMIC
COSN31486785 291 COSMIC
COSN31594623 315 COSMIC
COSN24365896 355 COSMIC
COSN20106999 373 COSMIC
COSN31516028 439 COSMIC
COSN30175097 637 COSMIC
COSN9203709 657 COSMIC
COSN20107001 767 COSMIC
COSN31585109 813 COSMIC
COSN31516034 819 COSMIC
COSN26635567 856 COSMIC
COSN31521065 917 COSMIC
COSN22896709 932 COSMIC
COSN31960464 1000 COSMIC
COSN1485039 1123 COSMIC
COSN17471335 1377 COSMIC
COSN20141349 1501 COSMIC
COSN6067960 1544 COSMIC
COSN6477786 1561 COSMIC
COSN25328320 1677 COSMIC
COSN25334174 1683 COSMIC
COSN25328321 1684 COSMIC
COSN26082484 1691 COSMIC
COSN26082427 1721 COSMIC
COSN17610042 1739 COSMIC
COSN26082369 1769 COSMIC
COSN26082344 1778 COSMIC
COSN26082311 1802 COSMIC
COSN29928362 1890 COSMIC
COSN19457151 2232 COSMIC
COSN29085006 2286 COSMIC
COSN8183793 2429 COSMIC
COSN23018597 2447 COSMIC
COSN22766608 2568 COSMIC
COSN15258009 2593 COSMIC
COSN6067961 2771 COSMIC
COSN24445370 3196 COSMIC
COSN6067962 3233 COSMIC
COSN23837945 3466 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1243512763 10 dbSNP
rs768797603 17 dbSNP
rs1294336205 23 dbSNP
rs777083832 30 dbSNP
rs574238898 32 dbSNP
rs201914472 38 dbSNP
rs750930190 41 dbSNP
rs1278418115 42 dbSNP
rs563168106 45 dbSNP
rs1230245296 47 dbSNP
rs1211194944 48 dbSNP
rs1317573082 52 dbSNP
rs1182457858 55 dbSNP
rs1311609632 55 dbSNP
rs984780064 57 dbSNP
rs910026101 60 dbSNP
rs1376517251 71 dbSNP
rs1337655706 74 dbSNP
rs1398112339 97 dbSNP
rs942894177 98 dbSNP
rs899869693 100 dbSNP
rs117751134 105 dbSNP
rs1421273899 121 dbSNP
rs1365021715 128 dbSNP
rs189066342 129 dbSNP
rs1438552408 132 dbSNP
rs1385396110 135 dbSNP
rs751844563 147 dbSNP
rs765113825 156 dbSNP
rs1255278169 158 dbSNP
rs771139691 159 dbSNP
rs1363788377 160 dbSNP
rs76913662 168 dbSNP
rs962973104 175 dbSNP
rs1237979581 189 dbSNP
rs902190426 192 dbSNP
rs1300217883 193 dbSNP
rs1315936534 198 dbSNP
rs1247319010 202 dbSNP
rs1339042747 206 dbSNP
rs528257795 208 dbSNP
rs1312539934 209 dbSNP
rs999425980 210 dbSNP
rs1362938851 213 dbSNP
rs1054126230 216 dbSNP
rs1418520588 218 dbSNP
rs755188865 229 dbSNP
rs974324306 231 dbSNP
rs1471631074 241 dbSNP
rs1012516501 242 dbSNP
rs1193705159 246 dbSNP
rs1430099352 247 dbSNP
rs1305994345 249 dbSNP
rs1322316894 266 dbSNP
rs1487990210 271 dbSNP
rs1246892798 272 dbSNP
rs1292643859 277 dbSNP
rs1211855035 279 dbSNP
rs1361442093 281 dbSNP
rs774510120 287 dbSNP
rs1289420788 289 dbSNP
rs372360009 290 dbSNP
rs1358125874 291 dbSNP
rs760583698 293 dbSNP
rs1265094808 302 dbSNP
rs1228523971 307 dbSNP
rs1342805091 313 dbSNP
rs1399984619 319 dbSNP
rs1345566090 323 dbSNP
rs1023722018 325 dbSNP
rs764085856 326 dbSNP
rs981082169 332 dbSNP
rs1205192953 340 dbSNP
rs928375617 345 dbSNP
rs1192813343 349 dbSNP
rs1421270108 349 dbSNP
rs769678745 349 dbSNP
rs796712349 349 dbSNP
rs1480760656 354 dbSNP
rs763615558 354 dbSNP
rs780015099 354 dbSNP
rs1169768673 355 dbSNP
rs1324959902 355 dbSNP
rs1329090617 355 dbSNP
rs1330035908 355 dbSNP
rs1397842285 355 dbSNP
rs1429484190 355 dbSNP
rs1448582231 355 dbSNP
rs145446729 355 dbSNP
rs1491261458 355 dbSNP
rs35294532 355 dbSNP
rs397847634 355 dbSNP
rs549232055 355 dbSNP
rs796818439 355 dbSNP
rs866309821 355 dbSNP
rs869141158 355 dbSNP
rs753614021 356 dbSNP
rs1479436908 357 dbSNP
rs934425165 358 dbSNP
rs1477052142 366 dbSNP
rs1250246019 368 dbSNP
rs1246254188 372 dbSNP
rs1179464710 374 dbSNP
rs866863631 375 dbSNP
rs1236721139 376 dbSNP
rs1462049411 376 dbSNP
rs571411052 376 dbSNP
rs1218030535 377 dbSNP
rs914420362 379 dbSNP
rs1343634282 393 dbSNP
rs947280148 401 dbSNP
rs1039010716 409 dbSNP
rs1241851822 415 dbSNP
rs1374120617 422 dbSNP
rs900425620 429 dbSNP
rs1330268635 430 dbSNP
rs1383874104 431 dbSNP
rs996813686 432 dbSNP
rs1424129075 436 dbSNP
rs181646213 438 dbSNP
rs1424549602 440 dbSNP
rs1159393740 444 dbSNP
rs1441640554 449 dbSNP
rs747764843 449 dbSNP
rs1378629447 452 dbSNP
rs1178293460 454 dbSNP
rs1483756403 457 dbSNP
rs1239619239 467 dbSNP
rs562162957 490 dbSNP
rs951476403 494 dbSNP
rs1460646180 497 dbSNP
rs1442407744 499 dbSNP
rs1285590763 503 dbSNP
rs984379175 504 dbSNP
rs891185805 505 dbSNP
rs1004727265 509 dbSNP
rs1308011598 511 dbSNP
rs1379625903 512 dbSNP
rs761649539 513 dbSNP
rs1381033001 515 dbSNP
rs964244018 516 dbSNP
rs1447186620 518 dbSNP
rs975588792 521 dbSNP
rs922781893 524 dbSNP
rs1421548843 535 dbSNP
rs1358728953 537 dbSNP
rs933033057 551 dbSNP
rs529399924 554 dbSNP
rs1416394127 558 dbSNP
rs1381900875 570 dbSNP
rs1228553107 571 dbSNP
rs764894590 571 dbSNP
rs1472674899 572 dbSNP
rs1264473009 573 dbSNP
rs923579767 576 dbSNP
rs1487008222 583 dbSNP
rs935019622 590 dbSNP
rs1221846477 594 dbSNP
rs1276132057 605 dbSNP
rs750110724 609 dbSNP
rs1227463900 610 dbSNP
rs1305468705 610 dbSNP
rs1362438401 610 dbSNP
rs1053690544 618 dbSNP
rs893753745 619 dbSNP
rs995712506 621 dbSNP
rs1012072899 624 dbSNP
rs1297721503 633 dbSNP
rs1256158702 635 dbSNP
rs550937994 636 dbSNP
rs1458486567 639 dbSNP
rs1483794167 650 dbSNP
rs1351764306 655 dbSNP
rs1044886456 657 dbSNP
rs906365968 659 dbSNP
rs1424845952 661 dbSNP
rs1196428518 663 dbSNP
rs1003604058 664 dbSNP
rs569124090 666 dbSNP
rs1261823677 667 dbSNP
rs757982830 667 dbSNP
rs1191215945 669 dbSNP
rs539843539 673 dbSNP
rs951397512 675 dbSNP
rs1023133303 676 dbSNP
rs1245428152 679 dbSNP
rs1205923170 680 dbSNP
rs970297112 684 dbSNP
rs1259798852 685 dbSNP
rs1216706905 687 dbSNP
rs1241873637 691 dbSNP
rs1301901131 692 dbSNP
rs1387381671 699 dbSNP
rs1369842830 705 dbSNP
rs1291976223 706 dbSNP
rs1436073482 707 dbSNP
rs752610628 710 dbSNP
rs551613310 719 dbSNP
rs981051006 720 dbSNP
rs1173351067 725 dbSNP
rs1401479063 725 dbSNP
rs1464407783 727 dbSNP
rs1423456597 734 dbSNP
rs1444537106 743 dbSNP
rs1035788880 744 dbSNP
rs955804298 755 dbSNP
rs1421733298 757 dbSNP
rs1422507583 758 dbSNP
rs1190243370 762 dbSNP
rs1457978963 763 dbSNP
rs1239630530 764 dbSNP
rs397761127 765 dbSNP
rs9335815 765 dbSNP
rs200954866 766 dbSNP
rs1256465754 770 dbSNP
rs989002662 771 dbSNP
rs1313993129 772 dbSNP
rs1299367278 775 dbSNP
rs777970754 789 dbSNP
rs1233827500 790 dbSNP
rs1359913553 793 dbSNP
rs1470851383 799 dbSNP
rs1334414473 800 dbSNP
rs1333622249 805 dbSNP
rs1405327992 816 dbSNP
rs1444975867 817 dbSNP
rs1017178718 819 dbSNP
rs1299265316 821 dbSNP
rs914411412 824 dbSNP
rs947167085 826 dbSNP
rs150035851 829 dbSNP
rs975639728 831 dbSNP
rs534123034 833 dbSNP
rs1174673437 848 dbSNP
rs1439773959 850 dbSNP
rs1381732260 853 dbSNP
rs1175383627 854 dbSNP
rs71676864 854 dbSNP
rs1301575843 871 dbSNP
rs146623575 872 dbSNP
rs765887041 875 dbSNP
rs760270783 880 dbSNP
rs1029762250 890 dbSNP
rs955551845 891 dbSNP
rs1482270266 895 dbSNP
rs1255355363 899 dbSNP
rs1313554583 917 dbSNP
rs987167874 919 dbSNP
rs1261643828 924 dbSNP
rs1238313221 925 dbSNP
rs1335517958 930 dbSNP
rs1048936 933 dbSNP
rs796555395 933 dbSNP
rs1398168266 939 dbSNP
rs1400608035 940 dbSNP
rs974579875 945 dbSNP
rs1419718127 946 dbSNP
rs989584316 949 dbSNP
rs1244278352 950 dbSNP
rs921815214 957 dbSNP
rs568129230 959 dbSNP
rs535167600 960 dbSNP
rs1426191970 963 dbSNP
rs891148459 968 dbSNP
rs1045019523 973 dbSNP
rs940110030 988 dbSNP
rs557040931 993 dbSNP
rs575082049 1000 dbSNP
rs939192620 1002 dbSNP
rs757514321 1003 dbSNP
rs140175278 1004 dbSNP
rs1457517903 1010 dbSNP
rs1247385160 1016 dbSNP
rs555065331 1025 dbSNP
rs887225919 1034 dbSNP
rs1401187216 1040 dbSNP
rs1005644005 1047 dbSNP
rs1295869720 1056 dbSNP
rs1017309216 1057 dbSNP
rs899851160 1058 dbSNP
rs898582456 1062 dbSNP
rs1171266642 1069 dbSNP
rs573222340 1070 dbSNP
rs78327869 1071 dbSNP
rs1191510824 1074 dbSNP
rs1446529359 1081 dbSNP
rs1268252960 1084 dbSNP
rs1211904307 1086 dbSNP
rs561902022 1089 dbSNP
rs1273022605 1097 dbSNP
rs186730042 1099 dbSNP
rs1282169691 1101 dbSNP
rs1320548507 1104 dbSNP
rs955520449 1109 dbSNP
rs1229341215 1113 dbSNP
rs538678207 1126 dbSNP
rs563827788 1128 dbSNP
rs563005264 1131 dbSNP
rs781373726 1133 dbSNP
rs746255050 1135 dbSNP
rs955939079 1139 dbSNP
rs1030741103 1140 dbSNP
rs191222621 1145 dbSNP
rs1490922220 1146 dbSNP
rs1021761099 1148 dbSNP
rs968467112 1155 dbSNP
rs1475110957 1159 dbSNP
rs34863247 1164 dbSNP
rs781703023 1164 dbSNP
rs989245220 1165 dbSNP
rs974547432 1167 dbSNP
rs914866482 1175 dbSNP
rs921784276 1176 dbSNP
rs933209940 1183 dbSNP
rs1459395311 1184 dbSNP
rs143932275 1185 dbSNP
rs947712063 1186 dbSNP
rs1214550467 1189 dbSNP
rs987827562 1190 dbSNP
rs377072953 1199 dbSNP
rs1230596102 1202 dbSNP
rs1405759967 1204 dbSNP
rs1369719498 1211 dbSNP
rs748553060 1215 dbSNP
rs1448654883 1220 dbSNP
rs534399126 1222 dbSNP
rs1164941986 1232 dbSNP
rs1366895978 1234 dbSNP
rs1397902272 1239 dbSNP
rs756531111 1248 dbSNP
rs1037043088 1253 dbSNP
rs1415037215 1253 dbSNP
rs1402984027 1256 dbSNP
rs939161521 1259 dbSNP
rs1394663590 1269 dbSNP
rs898563078 1272 dbSNP
rs931421169 1273 dbSNP
rs1302170797 1274 dbSNP
rs1044531505 1276 dbSNP
rs778216574 1281 dbSNP
rs1281616304 1292 dbSNP
rs1281366971 1298 dbSNP
rs1198164822 1301 dbSNP
rs886950097 1307 dbSNP
rs1309497985 1315 dbSNP
rs183080826 1316 dbSNP
rs1241916265 1319 dbSNP
rs566799237 1326 dbSNP
rs1036314845 1327 dbSNP
rs770106147 1330 dbSNP
rs1278797336 1342 dbSNP
rs1448498153 1346 dbSNP
rs1342120871 1347 dbSNP
rs1332152774 1357 dbSNP
rs1432892836 1364 dbSNP
rs1374977812 1366 dbSNP
rs1223713513 1367 dbSNP
rs1293057989 1368 dbSNP
rs1038467444 1369 dbSNP
rs1176929591 1370 dbSNP
rs899831943 1376 dbSNP
rs528010004 1386 dbSNP
rs892058453 1392 dbSNP
rs1485038843 1396 dbSNP
rs549281522 1400 dbSNP
rs11400714 1401 dbSNP
rs1218324207 1401 dbSNP
rs577530918 1405 dbSNP
rs1283122202 1410 dbSNP
rs1291364905 1411 dbSNP
rs1483489976 1412 dbSNP
rs1183791798 1416 dbSNP
rs1230956050 1417 dbSNP
rs1228631138 1423 dbSNP
rs1032215179 1424 dbSNP
rs1282336383 1426 dbSNP
rs957578474 1429 dbSNP
rs1021306904 1432 dbSNP
rs1182387476 1433 dbSNP
rs1401940944 1434 dbSNP
rs968437425 1435 dbSNP
rs567730502 1436 dbSNP
rs1406295231 1438 dbSNP
rs969042856 1443 dbSNP
rs1422246933 1448 dbSNP
rs539869195 1455 dbSNP
rs980470259 1455 dbSNP
rs1195128218 1457 dbSNP
rs954566309 1461 dbSNP
rs538435575 1465 dbSNP
rs560346547 1467 dbSNP
rs1221914260 1473 dbSNP
rs1331375519 1476 dbSNP
rs1271110956 1482 dbSNP
rs765543132 1483 dbSNP
rs907750166 1483 dbSNP
rs76170035 1485 dbSNP
rs973126444 1486 dbSNP
rs1288476726 1487 dbSNP
rs919957182 1487 dbSNP
rs931391447 1494 dbSNP
rs1351968122 1495 dbSNP
rs1461253492 1496 dbSNP
rs7074797 1496 dbSNP
rs1316385558 1498 dbSNP
rs932647084 1499 dbSNP
rs1173482098 1503 dbSNP
rs1426199100 1510 dbSNP
rs1044500549 1512 dbSNP
rs1191407623 1517 dbSNP
rs568976266 1519 dbSNP
rs999487753 1530 dbSNP
rs938816777 1535 dbSNP
rs775867204 1537 dbSNP
rs1053384146 1540 dbSNP
rs1259861269 1542 dbSNP
rs1202400111 1546 dbSNP
rs893279375 1548 dbSNP
rs1057315797 1550 dbSNP
rs1219897811 1551 dbSNP
rs1373383517 1551 dbSNP
rs1301563988 1553 dbSNP
rs1011768631 1554 dbSNP
rs1197779707 1557 dbSNP
rs1408509280 1558 dbSNP
rs1271075243 1560 dbSNP
rs332180 1561 dbSNP
rs201335559 1562 dbSNP
rs1329640870 1564 dbSNP
rs1176088250 1567 dbSNP
rs1244936953 1570 dbSNP
rs1434404452 1571 dbSNP
rs1160826044 1572 dbSNP
rs1337741690 1573 dbSNP
rs138511533 1573 dbSNP
rs1239845384 1575 dbSNP
rs557816060 1576 dbSNP
rs969095244 1577 dbSNP
rs1256520363 1578 dbSNP
rs1390252908 1580 dbSNP
rs749862558 1581 dbSNP
rs332181 1582 dbSNP
rs1233896453 1585 dbSNP
rs34785251 1585 dbSNP
rs1395263859 1586 dbSNP
rs1390043480 1587 dbSNP
rs1409786857 1588 dbSNP
rs1337773259 1591 dbSNP
rs983091432 1594 dbSNP
rs1451087653 1596 dbSNP
rs1336569659 1598 dbSNP
rs1467091525 1604 dbSNP
rs1327114592 1605 dbSNP
rs1229639945 1606 dbSNP
rs1268668789 1607 dbSNP
rs375941611 1607 dbSNP
rs1373147885 1608 dbSNP
rs1287411614 1609 dbSNP
rs1381791143 1609 dbSNP
rs144715449 1609 dbSNP
rs1183577681 1610 dbSNP
rs1210426318 1610 dbSNP
rs1308950262 1610 dbSNP
rs1354613115 1610 dbSNP
rs141005944 1610 dbSNP
rs1491091146 1610 dbSNP
rs754150237 1610 dbSNP
rs766774700 1610 dbSNP
rs9331408 1610 dbSNP
rs1262722626 1615 dbSNP
rs1338947357 1624 dbSNP
rs1223942592 1627 dbSNP
rs908479221 1627 dbSNP
rs1314042180 1628 dbSNP
rs1264757814 1629 dbSNP
rs1311680559 1630 dbSNP
rs1353002457 1630 dbSNP
rs1459978981 1631 dbSNP
rs1333375761 1632 dbSNP
rs1202966651 1633 dbSNP
rs1262275006 1634 dbSNP
rs1156465921 1635 dbSNP
rs1448249230 1636 dbSNP
rs1190352176 1637 dbSNP
rs1372190143 1642 dbSNP
rs1478141726 1643 dbSNP
rs1177682754 1650 dbSNP
rs1431907067 1653 dbSNP
rs1468511165 1662 dbSNP
rs77769382 1663 dbSNP
rs1386262747 1666 dbSNP
rs1187229487 1668 dbSNP
rs1384035337 1669 dbSNP
rs1264067712 1670 dbSNP
rs1203667777 1672 dbSNP
rs1316285475 1673 dbSNP
rs1485730863 1675 dbSNP
rs1266458295 1678 dbSNP
rs1235540938 1685 dbSNP
rs555658750 1693 dbSNP
rs1405777935 1696 dbSNP
rs80035283 1698 dbSNP
rs1327729468 1699 dbSNP
rs1321172592 1705 dbSNP
rs769037574 1709 dbSNP
rs1391170602 1711 dbSNP
rs1222626108 1712 dbSNP
rs904221501 1713 dbSNP
rs995923139 1714 dbSNP
rs761619409 1717 dbSNP
rs1171329977 1719 dbSNP
rs932698119 1720 dbSNP
rs1352720341 1730 dbSNP
rs1051141683 1731 dbSNP
rs912533306 1746 dbSNP
rs1053759507 1748 dbSNP
rs934705078 1748 dbSNP
rs1467431739 1754 dbSNP
rs1273082607 1755 dbSNP
rs893424317 1755 dbSNP
rs544407383 1761 dbSNP
rs1012252299 1762 dbSNP
rs1267958862 1763 dbSNP
rs765025149 1769 dbSNP
rs1331259681 1773 dbSNP
rs146783183 1774 dbSNP
rs1009117955 1776 dbSNP
rs1331922737 1781 dbSNP
rs1411660048 1784 dbSNP
rs906051036 1786 dbSNP
rs1001926457 1790 dbSNP
rs1201147741 1791 dbSNP
rs1461571459 1794 dbSNP
rs576103297 1809 dbSNP
rs896122995 1811 dbSNP
rs778876820 1820 dbSNP
rs1252835735 1821 dbSNP
rs1015918669 1823 dbSNP
rs1014784158 1825 dbSNP
rs1364929220 1827 dbSNP
rs1271510408 1828 dbSNP
rs1194700118 1829 dbSNP
rs1345140890 1831 dbSNP
rs1281998044 1835 dbSNP
rs758270007 1835 dbSNP
rs1455793263 1836 dbSNP
rs41344150 1838 dbSNP
rs973379378 1844 dbSNP
rs1309636584 1851 dbSNP
rs1444111667 1852 dbSNP
rs544983896 1853 dbSNP
rs1425317809 1864 dbSNP
rs1028089307 1879 dbSNP
rs1376183432 1881 dbSNP
rs1433156823 1891 dbSNP
rs1394719212 1899 dbSNP
rs1159442674 1923 dbSNP
rs1343833979 1924 dbSNP
rs766017466 1926 dbSNP
rs986832459 1928 dbSNP
rs1181781447 1930 dbSNP
rs952676154 1931 dbSNP
rs980081794 1933 dbSNP
rs1404155817 1935 dbSNP
rs1259091869 1937 dbSNP
rs1208267335 1938 dbSNP
rs777276080 1941 dbSNP
rs79734057 1941 dbSNP
rs1225206482 1947 dbSNP
rs927355045 1953 dbSNP
rs372664066 1963 dbSNP
rs527384444 1963 dbSNP
rs560080990 1965 dbSNP
rs148933733 1970 dbSNP
rs1356157084 1971 dbSNP
rs938800711 1988 dbSNP
rs549218061 1989 dbSNP
rs1057478497 1992 dbSNP
rs532908958 1994 dbSNP
rs1375032818 2000 dbSNP
rs531804640 2011 dbSNP
rs1319256419 2012 dbSNP
rs913427821 2017 dbSNP
rs1406295884 2022 dbSNP
rs946282063 2030 dbSNP
rs1158497291 2037 dbSNP
rs1289194634 2039 dbSNP
rs906018344 2043 dbSNP
rs185403186 2046 dbSNP
rs1485070118 2051 dbSNP
rs1056225173 2052 dbSNP
rs1251683986 2057 dbSNP
rs1217547343 2059 dbSNP
rs1421185043 2059 dbSNP
rs1180306773 2064 dbSNP
rs1380175337 2068 dbSNP
rs1336774812 2080 dbSNP
rs1291398703 2082 dbSNP
rs1445353758 2092 dbSNP
rs896269980 2102 dbSNP
rs868705332 2105 dbSNP
rs1289638744 2112 dbSNP
rs904778384 2113 dbSNP
rs568838815 2115 dbSNP
rs1343796222 2117 dbSNP
rs1165517402 2122 dbSNP
rs1364003989 2123 dbSNP
rs1424253127 2124 dbSNP
rs1298890360 2132 dbSNP
rs1004377125 2143 dbSNP
rs1398378623 2149 dbSNP
rs189723466 2152 dbSNP
rs898173144 2156 dbSNP
rs1187890602 2157 dbSNP
rs865820270 2157 dbSNP
rs1474189289 2161 dbSNP
rs995808557 2162 dbSNP
rs551867707 2165 dbSNP
rs1050101095 2167 dbSNP
rs1271173437 2173 dbSNP
rs953861193 2175 dbSNP
rs1321197342 2176 dbSNP
rs986634261 2177 dbSNP
rs1019876238 2180 dbSNP
rs332182 2181 dbSNP
rs754491043 2184 dbSNP
rs1358369434 2186 dbSNP
rs989322704 2188 dbSNP
rs1324464422 2194 dbSNP
rs914552040 2202 dbSNP
rs1252643802 2209 dbSNP
rs1015164002 2211 dbSNP
rs766148797 2212 dbSNP
rs1171824393 2224 dbSNP
rs947404683 2226 dbSNP
rs1418293534 2232 dbSNP
rs897698812 2233 dbSNP
rs143696726 2237 dbSNP
rs533776087 2248 dbSNP
rs969291728 2249 dbSNP
rs927571471 2250 dbSNP
rs1238148717 2253 dbSNP
rs1253017083 2256 dbSNP
rs183527632 2258 dbSNP
rs1305884539 2259 dbSNP
rs1274149678 2263 dbSNP
rs1235380374 2264 dbSNP
rs1057285609 2265 dbSNP
rs886608491 2272 dbSNP
rs527639718 2274 dbSNP
rs1300451125 2275 dbSNP
rs939762641 2275 dbSNP
rs547484471 2278 dbSNP
rs1185566344 2287 dbSNP
rs1353463974 2294 dbSNP
rs1037201807 2296 dbSNP
rs1436270141 2297 dbSNP
rs1345044868 2303 dbSNP
rs1392880184 2304 dbSNP
rs776378372 2305 dbSNP
rs1034334179 2309 dbSNP
rs1172715046 2309 dbSNP
rs1252546108 2310 dbSNP
rs766895234 2312 dbSNP
rs992959463 2314 dbSNP
rs1479692354 2315 dbSNP
rs1251263786 2316 dbSNP
rs913386672 2322 dbSNP
rs187819938 2325 dbSNP
rs530268532 2325 dbSNP
rs946196132 2332 dbSNP
rs889733233 2334 dbSNP
rs759407349 2335 dbSNP
rs1232937828 2336 dbSNP
rs1317940036 2339 dbSNP
rs1309758875 2341 dbSNP
rs926164148 2342 dbSNP
rs1312880922 2349 dbSNP
rs537620050 2350 dbSNP
rs556355659 2355 dbSNP
rs1454104723 2361 dbSNP
rs1406471400 2375 dbSNP
rs1454381373 2376 dbSNP
rs1050075346 2380 dbSNP
rs1010310514 2383 dbSNP
rs890162542 2387 dbSNP
rs332183 2390 dbSNP
rs1486712846 2391 dbSNP
rs1036074339 2392 dbSNP
rs1255631726 2393 dbSNP
rs1200142036 2398 dbSNP
rs1486389246 2404 dbSNP
rs968705054 2407 dbSNP
rs1237339049 2414 dbSNP
rs1214844883 2422 dbSNP
rs897578550 2423 dbSNP
rs994602692 2426 dbSNP
rs1027466341 2429 dbSNP
rs1305286988 2430 dbSNP
rs1353079636 2432 dbSNP
rs545070994 2433 dbSNP
rs756519427 2438 dbSNP
rs1382502692 2439 dbSNP
rs1386693414 2443 dbSNP
rs167967 2445 dbSNP
rs549939761 2446 dbSNP
rs1034753723 2450 dbSNP
rs1395076947 2452 dbSNP
rs749665604 2453 dbSNP
rs1257988741 2458 dbSNP
rs1462211537 2463 dbSNP
rs1205957284 2470 dbSNP
rs1187099148 2472 dbSNP
rs1429270040 2481 dbSNP
rs1241740894 2487 dbSNP
rs993238586 2498 dbSNP
rs1464751269 2511 dbSNP
rs1020333482 2513 dbSNP
rs967467615 2518 dbSNP
rs1332030398 2519 dbSNP
rs978900787 2519 dbSNP
rs1227540522 2520 dbSNP
rs1483032096 2525 dbSNP
rs1187362453 2530 dbSNP
rs926138397 2534 dbSNP
rs374777236 2536 dbSNP
rs1169790730 2545 dbSNP
rs1429901455 2551 dbSNP
rs193203810 2552 dbSNP
rs912134515 2558 dbSNP
rs1173960234 2560 dbSNP
rs944355665 2561 dbSNP
rs560509992 2567 dbSNP
rs1389927475 2573 dbSNP
rs1162677144 2578 dbSNP
rs1462578861 2580 dbSNP
rs930971427 2580 dbSNP
rs1191368725 2586 dbSNP
rs1449231683 2587 dbSNP
rs1254096408 2591 dbSNP
rs1049347877 2593 dbSNP
rs561421886 2596 dbSNP
rs1181122945 2598 dbSNP
rs1290286338 2601 dbSNP
rs1195830890 2602 dbSNP
rs561447632 2603 dbSNP
rs1381162490 2609 dbSNP
rs1008073617 2611 dbSNP
rs1041392070 2615 dbSNP
rs930420812 2618 dbSNP
rs1324869172 2621 dbSNP
rs1348317223 2627 dbSNP
rs1305269476 2628 dbSNP
rs183379262 2632 dbSNP
rs1261618097 2633 dbSNP
rs1330396714 2633 dbSNP
rs1010525585 2640 dbSNP
rs758430472 2641 dbSNP
rs796408974 2642 dbSNP
rs1429277023 2643 dbSNP
rs1002071497 2644 dbSNP
rs1477263264 2649 dbSNP
rs1244063742 2652 dbSNP
rs968757379 2655 dbSNP
rs1485054071 2659 dbSNP
rs1056342748 2661 dbSNP
rs1193023689 2668 dbSNP
rs1439027988 2669 dbSNP
rs1247886853 2670 dbSNP
rs1203814912 2672 dbSNP
rs1485760815 2674 dbSNP
rs1001622140 2686 dbSNP
rs1231749895 2692 dbSNP
rs1344079527 2697 dbSNP
rs1280041383 2700 dbSNP
rs1034326605 2706 dbSNP
rs1269753330 2707 dbSNP
rs1481358173 2710 dbSNP
rs896400479 2714 dbSNP
rs1014227027 2716 dbSNP
rs1197225755 2716 dbSNP
rs1409312196 2718 dbSNP
rs1376253330 2719 dbSNP
rs1315058192 2740 dbSNP
rs1020722527 2741 dbSNP
rs1401085413 2742 dbSNP
rs1159648253 2746 dbSNP
rs960041633 2750 dbSNP
rs1410417336 2752 dbSNP
rs1180762946 2763 dbSNP
rs1265829 2769 dbSNP
rs1208336987 2775 dbSNP
rs1441632732 2777 dbSNP
rs1343064252 2779 dbSNP
rs993080863 2781 dbSNP
rs1206689495 2784 dbSNP
rs1418766606 2786 dbSNP
rs1000316245 2787 dbSNP
rs1033176889 2797 dbSNP
rs12776222 2802 dbSNP
rs1356231628 2802 dbSNP
rs1295335781 2806 dbSNP
rs1446175419 2808 dbSNP
rs1439517663 2812 dbSNP
rs868237289 2812 dbSNP
rs1273172742 2813 dbSNP
rs867045968 2815 dbSNP
rs1346884411 2817 dbSNP
rs1159123025 2818 dbSNP
rs1433531061 2818 dbSNP
rs1034026550 2819 dbSNP
rs1179616111 2819 dbSNP
rs1214309836 2820 dbSNP
rs1226694177 2820 dbSNP
rs1242364603 2820 dbSNP
rs1267403220 2820 dbSNP
rs1271020056 2820 dbSNP
rs1275056050 2820 dbSNP
rs1312918458 2820 dbSNP
rs1320454791 2820 dbSNP
rs1335541907 2820 dbSNP
rs1363521651 2820 dbSNP
rs1378653863 2820 dbSNP
rs1433284628 2820 dbSNP
rs1463411175 2820 dbSNP
rs532993254 2820 dbSNP
rs71391056 2820 dbSNP
rs895603993 2820 dbSNP
rs1237209582 2825 dbSNP
rs1407246422 2826 dbSNP
rs1273596274 2830 dbSNP
rs1367263815 2831 dbSNP
rs565443729 2832 dbSNP
rs1157166388 2833 dbSNP
rs1404279273 2833 dbSNP
rs1286853833 2834 dbSNP
rs1315327508 2835 dbSNP
rs1216213374 2837 dbSNP
rs35804351 2837 dbSNP
rs1469718939 2838 dbSNP
rs962231773 2839 dbSNP
rs1490866722 2840 dbSNP
rs1220081424 2849 dbSNP
rs974012052 2850 dbSNP
rs142343459 2857 dbSNP
rs1470507813 2859 dbSNP
rs1178709114 2861 dbSNP
rs1442133252 2864 dbSNP
rs1373782328 2870 dbSNP
rs1405575859 2870 dbSNP
rs1438655416 2871 dbSNP
rs953488065 2873 dbSNP
rs1354670012 2879 dbSNP
rs1172084706 2882 dbSNP
rs986713666 2882 dbSNP
rs1422220762 2883 dbSNP
rs912120323 2886 dbSNP
rs1173976461 2890 dbSNP
rs1455445006 2891 dbSNP
rs920770166 2895 dbSNP
rs931043095 2898 dbSNP
rs966715044 2899 dbSNP
rs751690774 2900 dbSNP
rs1233587210 2901 dbSNP
rs1207404608 2907 dbSNP
rs910877410 2909 dbSNP
rs60912564 2912 dbSNP
rs1443622136 2913 dbSNP
rs1281604197 2918 dbSNP
rs61477177 2922 dbSNP
rs1314359614 2924 dbSNP
rs532779042 2926 dbSNP
rs918949694 2928 dbSNP
rs1239629792 2929 dbSNP
rs12775282 2934 dbSNP
rs1040965253 2939 dbSNP
rs1407477426 2941 dbSNP
rs1369512758 2946 dbSNP
rs1048835032 2949 dbSNP
rs926379259 2950 dbSNP
rs1357268751 2954 dbSNP
rs1436327272 2954 dbSNP
rs1175261495 2957 dbSNP
rs188488926 2961 dbSNP
rs1056715652 2963 dbSNP
rs1184389640 2967 dbSNP
rs1438296884 2978 dbSNP
rs1206579874 2979 dbSNP
rs945993382 2986 dbSNP
rs1484441340 2988 dbSNP
rs1254564942 2998 dbSNP
rs896381091 2999 dbSNP
rs1230917339 3001 dbSNP
rs1009922341 3006 dbSNP
rs1457166224 3006 dbSNP
rs373665731 3007 dbSNP
rs750580160 3014 dbSNP
rs772226733 3023 dbSNP
rs1442458308 3030 dbSNP
rs1043241416 3031 dbSNP
rs1293511282 3035 dbSNP
rs1397482441 3038 dbSNP
rs372152124 3044 dbSNP
rs1001591046 3045 dbSNP
rs903223088 3049 dbSNP
rs1331484676 3061 dbSNP
rs375718590 3062 dbSNP
rs557402359 3064 dbSNP
rs895798926 3065 dbSNP
rs1033059280 3066 dbSNP
rs953454247 3067 dbSNP
rs1242939750 3068 dbSNP
rs1015166784 3082 dbSNP
rs192709365 3088 dbSNP
rs1019552105 3089 dbSNP
rs1340183271 3098 dbSNP
rs567431554 3100 dbSNP
rs1027752229 3101 dbSNP
rs1207450118 3106 dbSNP
rs953578186 3112 dbSNP
rs966304355 3118 dbSNP
rs911011360 3119 dbSNP
rs1338299670 3121 dbSNP
rs1317294090 3124 dbSNP
rs943709999 3130 dbSNP
rs972762754 3131 dbSNP
rs976792463 3131 dbSNP
rs918923253 3134 dbSNP
rs758357881 3137 dbSNP
rs538107761 3138 dbSNP
rs1318456641 3141 dbSNP
rs1434195309 3147 dbSNP
rs1395144525 3150 dbSNP
rs945930197 3152 dbSNP
rs984430764 3160 dbSNP
rs1459536789 3162 dbSNP
rs565790907 3167 dbSNP
rs1164406992 3171 dbSNP
rs769710205 3174 dbSNP
rs1250361076 3175 dbSNP
rs556203107 3177 dbSNP
rs1187070038 3178 dbSNP
rs1464793741 3179 dbSNP
rs144460877 3182 dbSNP
rs904344011 3182 dbSNP
rs1353712423 3187 dbSNP
rs372316480 3188 dbSNP
rs1343863124 3191 dbSNP
rs533739911 3192 dbSNP
rs1055884576 3194 dbSNP
rs1434122994 3200 dbSNP
rs926346714 3204 dbSNP
rs10160179 3216 dbSNP
rs1388569728 3221 dbSNP
rs146981447 3223 dbSNP
rs4747624 3225 dbSNP
rs945310933 3227 dbSNP
rs553524956 3228 dbSNP
rs1422098551 3230 dbSNP
rs995486311 3232 dbSNP
rs371600930 3233 dbSNP
rs1396189840 3235 dbSNP
rs1201726058 3238 dbSNP
rs1408805653 3239 dbSNP
rs953547128 3240 dbSNP
rs1195888563 3241 dbSNP
rs986295938 3243 dbSNP
rs573873109 3246 dbSNP
rs553838997 3247 dbSNP
rs1231060690 3248 dbSNP
rs889185127 3249 dbSNP
rs866987211 3251 dbSNP
rs184767621 3252 dbSNP
rs1008083983 3253 dbSNP
rs1339732201 3254 dbSNP
rs1429502533 3259 dbSNP
rs1403441692 3262 dbSNP
rs976546396 3268 dbSNP
rs542980408 3270 dbSNP
rs1377580595 3273 dbSNP
rs1182222980 3277 dbSNP
rs1019976887 3281 dbSNP
rs1473308612 3282 dbSNP
rs1204073737 3289 dbSNP
rs945760270 3303 dbSNP
rs542634648 3304 dbSNP
rs1284520340 3305 dbSNP
rs769255661 3311 dbSNP
rs937147552 3313 dbSNP
rs1261269897 3314 dbSNP
rs1261894703 3314 dbSNP
rs138158200 3315 dbSNP
rs1229062379 3316 dbSNP
rs1352471876 3317 dbSNP
rs116561759 3320 dbSNP
rs1409373363 3324 dbSNP
rs1341311931 3327 dbSNP
rs544068367 3329 dbSNP
rs1200814762 3336 dbSNP
rs917090533 3337 dbSNP
rs950150901 3342 dbSNP
rs1160615447 3347 dbSNP
rs1458345829 3347 dbSNP
rs1409217811 3350 dbSNP
rs952312053 3353 dbSNP
rs1472887440 3354 dbSNP
rs1036478872 3359 dbSNP
rs867448167 3360 dbSNP
rs1185089323 3361 dbSNP
rs565319860 3363 dbSNP
rs1284857873 3366 dbSNP
rs1033329682 3377 dbSNP
rs1210591364 3381 dbSNP
rs780863096 3381 dbSNP
rs1327007383 3384 dbSNP
rs1266255645 3386 dbSNP
rs532634459 3387 dbSNP
rs1402709867 3388 dbSNP
rs1286217702 3392 dbSNP
rs994889431 3393 dbSNP
rs1049293298 3396 dbSNP
rs1321801947 3401 dbSNP
rs1437818974 3403 dbSNP
rs1296385727 3404 dbSNP
rs959139529 3404 dbSNP
rs779238340 3409 dbSNP
rs992356509 3410 dbSNP
rs889333306 3420 dbSNP
rs1339981137 3425 dbSNP
rs917677648 3426 dbSNP
rs1285129161 3428 dbSNP
rs945169519 3428 dbSNP
rs977932020 3429 dbSNP
rs1248344987 3434 dbSNP
rs1190294340 3440 dbSNP
rs1463451395 3441 dbSNP
rs925165563 3442 dbSNP
rs1215121660 3443 dbSNP
rs1452302049 3449 dbSNP
rs1292275352 3455 dbSNP
rs1232250195 3463 dbSNP
rs1279978732 3464 dbSNP
rs1226884717 3466 dbSNP
rs1298716224 3475 dbSNP
rs1231099639 3479 dbSNP
rs1019048783 3484 dbSNP
rs1320517733 3484 dbSNP
rs1436559172 3490 dbSNP
rs936594801 3490 dbSNP
rs1351186253 3495 dbSNP
rs1214045077 3497 dbSNP
rs1054444926 3501 dbSNP
rs141836336 3505 dbSNP
rs372440445 3505 dbSNP
rs532714816 3505 dbSNP
rs11007163 3507 dbSNP
rs746546329 3507 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uugagacucaaaCAGAAAGGGu 5'
                      | ||||||| 
Target 5' ------------GCCUUUCCCu 3'
 		1 - 10
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HCT116
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in ERX177600. RNA binding protein: AGO2. Condition:p53_V_Ago_CLIP_2_2 PAR-CLIP data was present in ERX177624. RNA binding protein: AGO2. Condition:p53_V_AGO_CLIP_4_2 PAR-CLIP data was present in ERX177622. RNA binding protein: AGO2. Condition:KO_V_AGO_CLIP_3_12 ...

- Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research.

Article - Krell J; Stebbing J; Carissimi C; Dabrowska et al.
- Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000375664.4 | 3UTR | GCCUUUCCCUCCCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
161 hsa-miR-6733-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT075325 SF3B3 splicing factor 3b subunit 3 2 4
MIRT082764 EPN1 epsin 1 2 4
MIRT119868 NRBP1 nuclear receptor binding protein 1 2 2
MIRT124577 PRRC2B proline rich coiled-coil 2B 2 2
MIRT126718 WAC WW domain containing adaptor with coiled-coil 2 2
MIRT128925 KMT2A lysine methyltransferase 2A 2 2
MIRT135191 TMBIM6 transmembrane BAX inhibitor motif containing 6 2 2
MIRT145630 LASP1 LIM and SH3 protein 1 2 2
MIRT175518 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT188406 ATXN7L3B ataxin 7 like 3B 2 2
MIRT192486 KNSTRN kinetochore localized astrin/SPAG5 binding protein 2 2
MIRT208383 SLC25A36 solute carrier family 25 member 36 2 2
MIRT216690 F2R coagulation factor II thrombin receptor 2 2
MIRT235839 FAM217B family with sequence similarity 217 member B 2 2
MIRT257000 RGMB repulsive guidance molecule family member b 2 2
MIRT266594 POGZ pogo transposable element derived with ZNF domain 2 2
MIRT273614 SP1 Sp1 transcription factor 2 2
MIRT276567 AKAP11 A-kinase anchoring protein 11 2 2
MIRT285544 CDT1 chromatin licensing and DNA replication factor 1 2 2
MIRT291540 LRRC8B leucine rich repeat containing 8 VRAC subunit B 2 2
MIRT317159 E2F3 E2F transcription factor 3 2 4
MIRT340688 THRAP3 thyroid hormone receptor associated protein 3 2 2
MIRT366934 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 2
MIRT376193 AP1M1 adaptor related protein complex 1 mu 1 subunit 2 2
MIRT441983 TSTD2 thiosulfate sulfurtransferase like domain containing 2 2 2
MIRT442059 POU3F2 POU class 3 homeobox 2 2 6
MIRT443190 PDHA1 pyruvate dehydrogenase E1 alpha 1 subunit 2 2
MIRT445133 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT445881 WBP1L WW domain binding protein 1 like 2 2
MIRT449359 DPP6 dipeptidyl peptidase like 6 2 2
MIRT451399 FARSA phenylalanyl-tRNA synthetase alpha subunit 2 2
MIRT451802 CDCA3 cell division cycle associated 3 2 4
MIRT452295 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT452494 HMGXB3 HMG-box containing 3 2 2
MIRT453354 ZNF3 zinc finger protein 3 2 2
MIRT453375 CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 2 2
MIRT453719 RAP1GDS1 Rap1 GTPase-GDP dissociation stimulator 1 2 2
MIRT453839 SDK1 sidekick cell adhesion molecule 1 2 2
MIRT454009 ALKBH5 alkB homolog 5, RNA demethylase 2 2
MIRT454371 PIGS phosphatidylinositol glycan anchor biosynthesis class S 2 2
MIRT454729 ARSK arylsulfatase family member K 2 2
MIRT455227 KIAA2013 KIAA2013 2 2
MIRT455866 SLC35C2 solute carrier family 35 member C2 2 2
MIRT456386 KLHL12 kelch like family member 12 2 2
MIRT457017 ACADSB acyl-CoA dehydrogenase, short/branched chain 2 2
MIRT457048 NEGR1 neuronal growth regulator 1 2 2
MIRT457402 BACE2 beta-site APP-cleaving enzyme 2 2 2
MIRT457808 KLHL25 kelch like family member 25 2 2
MIRT458361 C3orf80 chromosome 3 open reading frame 80 2 2
MIRT458678 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT459629 GABARAP GABA type A receptor-associated protein 2 2
MIRT460955 MUL1 mitochondrial E3 ubiquitin protein ligase 1 2 2
MIRT462241 PRSS16 protease, serine 16 2 2
MIRT462472 FIZ1 FLT3 interacting zinc finger 1 2 2
MIRT462572 STS steroid sulfatase 2 2
MIRT462931 ZNF827 zinc finger protein 827 2 2
MIRT463442 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT464129 VPS35 VPS35, retromer complex component 2 2
MIRT464688 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT465653 TNPO2 transportin 2 2 2
MIRT465951 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466032 TMEM189 transmembrane protein 189 2 2
MIRT466577 TBC1D2B TBC1 domain family member 2B 2 2
MIRT467506 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 2
MIRT467786 SLC2A14 solute carrier family 2 member 14 2 2
MIRT468104 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT468292 SFT2D2 SFT2 domain containing 2 2 2
MIRT469004 RNF41 ring finger protein 41 2 2
MIRT469753 RAB2B RAB2B, member RAS oncogene family 2 2
MIRT473205 MINK1 misshapen like kinase 1 2 4
MIRT473314 MEX3A mex-3 RNA binding family member A 2 2
MIRT473549 MAVS mitochondrial antiviral signaling protein 2 2
MIRT474269 LATS2 large tumor suppressor kinase 2 2 2
MIRT475111 IPPK inositol-pentakisphosphate 2-kinase 2 2
MIRT475436 HYOU1 hypoxia up-regulated 1 2 2
MIRT475751 HDLBP high density lipoprotein binding protein 2 2
MIRT475972 GTPBP2 GTP binding protein 2 2 2
MIRT476480 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT476595 G3BP1 G3BP stress granule assembly factor 1 2 2
MIRT476684 FURIN furin, paired basic amino acid cleaving enzyme 2 2
MIRT477261 ERGIC2 ERGIC and golgi 2 2 2
MIRT477647 EFNA1 ephrin A1 2 2
MIRT477790 E2F2 E2F transcription factor 2 2 2
MIRT477871 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT478012 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT479558 CDC5L cell division cycle 5 like 2 4
MIRT480420 C17orf85 nuclear cap binding subunit 3 2 2
MIRT480642 BSCL2 BSCL2, seipin lipid droplet biogenesis associated 2 2
MIRT480778 BMP2 bone morphogenetic protein 2 2 2
MIRT481554 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT481689 AR androgen receptor 2 2
MIRT481836 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT483138 FOXC1 forkhead box C1 2 2
MIRT483919 SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2 2
MIRT484202 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT484433 RAB7A RAB7A, member RAS oncogene family 2 4
MIRT485544 GP5 glycoprotein V platelet 2 2
MIRT486558 SLC38A4 solute carrier family 38 member 4 2 2
MIRT486727 MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 2 4
MIRT490490 GLRA3 glycine receptor alpha 3 2 2
MIRT490682 SSTR1 somatostatin receptor 1 2 2
MIRT490792 PSMD3 proteasome 26S subunit, non-ATPase 3 2 2
MIRT491060 ACVR1B activin A receptor type 1B 2 4
MIRT492614 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT492768 PDGFB platelet derived growth factor subunit B 2 2
MIRT493988 EHD1 EH domain containing 1 2 2
MIRT494510 BDNF-AS BDNF antisense RNA 2 2
MIRT494755 AP3M2 adaptor related protein complex 3 mu 2 subunit 2 2
MIRT499802 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT501336 RNF44 ring finger protein 44 2 4
MIRT509490 CENPA centromere protein A 2 2
MIRT509643 ZNF354B zinc finger protein 354B 2 10
MIRT510147 PDGFRA platelet derived growth factor receptor alpha 2 4
MIRT510567 UNG uracil DNA glycosylase 2 6
MIRT525087 FRK fyn related Src family tyrosine kinase 2 2
MIRT528452 NXT2 nuclear transport factor 2 like export factor 2 2 4
MIRT531970 C12orf49 chromosome 12 open reading frame 49 2 2
MIRT532084 RTTN rotatin 2 2
MIRT532756 LDHD lactate dehydrogenase D 2 2
MIRT535072 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT535637 NPEPPS aminopeptidase puromycin sensitive 2 2
MIRT545410 EIF4A3 eukaryotic translation initiation factor 4A3 2 4
MIRT545911 ZFP91 ZFP91 zinc finger protein 2 4
MIRT548007 GRB2 growth factor receptor bound protein 2 2 4
MIRT548545 DR1 down-regulator of transcription 1 2 2
MIRT550075 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT553730 TBRG1 transforming growth factor beta regulator 1 2 2
MIRT557569 GNPTAB N-acetylglucosamine-1-phosphate transferase alpha and beta subunits 2 2
MIRT558025 EXT1 exostosin glycosyltransferase 1 2 2
MIRT558139 ENC1 ectodermal-neural cortex 1 2 2
MIRT560173 COA1 cytochrome c oxidase assembly factor 1 homolog 2 2
MIRT561700 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT565101 UBE3C ubiquitin protein ligase E3C 2 2
MIRT565739 SESN3 sestrin 3 2 2
MIRT566669 NACC2 NACC family member 2 2 2
MIRT567040 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT569627 ZNF746 zinc finger protein 746 2 2
MIRT570530 RPH3A rabphilin 3A 2 2
MIRT570939 CPE carboxypeptidase E 2 2
MIRT574774 FGF2 fibroblast growth factor 2 2 2
MIRT620120 LACC1 laccase domain containing 1 2 2
MIRT624338 CISD1 CDGSH iron sulfur domain 1 2 2
MIRT625434 RMDN1 regulator of microtubule dynamics 1 2 2
MIRT640528 TET3 tet methylcytosine dioxygenase 3 2 4
MIRT646916 TRIM14 tripartite motif containing 14 2 2
MIRT656298 METTL1 methyltransferase like 1 2 2
MIRT660192 BMPR1A bone morphogenetic protein receptor type 1A 2 2
MIRT661360 DYRK4 dual specificity tyrosine phosphorylation regulated kinase 4 2 2
MIRT667769 KCTD11 potassium channel tetramerization domain containing 11 2 2
MIRT683187 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D 2 2
MIRT685843 ANGEL1 angel homolog 1 2 2
MIRT688553 DCAF16 DDB1 and CUL4 associated factor 16 2 2
MIRT689424 CYB561 cytochrome b561 2 2
MIRT698505 TGFBR1 transforming growth factor beta receptor 1 2 2
MIRT701232 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT702506 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT706488 SEPT6 septin 6 2 2
MIRT713774 ZNF460 zinc finger protein 460 2 2
MIRT716991 ARL6IP4 ADP ribosylation factor like GTPase 6 interacting protein 4 2 2
MIRT722644 MPEG1 macrophage expressed 1 2 2
MIRT725254 PARVB parvin beta 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6733 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-6733 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-6733-5p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-6733-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-6733-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-6733-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)

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