miRTarBase - #MIRT138721


—
pre-miRNA Information
pre-miRNA hsa-mir-548f-1   
Genomic Coordinates chr10: 54607874 - 54607957
Synonyms MIR548F-1, MIRN548F1, hsa-mir-548f-1, MIR548F1
Description Homo sapiens miR-548f-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-548f-2   
Genomic Coordinates chr2: 212426263 - 212426360
Synonyms MIR548F-2, MIRN548F2, hsa-mir-548f-2, MIR548F2
Description Homo sapiens miR-548f-2 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-548f-3   
Genomic Coordinates chr5: 110513829 - 110513915
Synonyms MIR548F-3, MIRN548F3, hsa-mir-548f-3, MIR548F3
Description Homo sapiens miR-548f-3 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-548f-4   
Genomic Coordinates chr7: 147378017 - 147378121
Synonyms MIR548F-4, MIRN548F4, hsa-mir-548f-4, MIR548F4
Description Homo sapiens miR-548f-4 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-548f-5   
Genomic Coordinates chrX: 32641474 - 32641559
Synonyms MIR548F-5, MIRN548F5, hsa-mir-548f-5, MIR548F5
Description Homo sapiens miR-548f-5 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-548f-3p
Sequence 59| AAAAACUGUAAUUACUUUU |77
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 10 - 54607905 29233923 MiREDiBase
A-to-I 4 10 - 54607904 29233923 MiREDiBase
A-to-I 5 10 - 54607903 29233923 MiREDiBase
A-to-I 10 10 - 54607898 29233923 MiREDiBase
A-to-I 3 2 - 212426300 29233923 MiREDiBase
A-to-I 4 2 - 212426299 29233923 MiREDiBase
A-to-I 5 2 - 212426298 29233923 MiREDiBase
A-to-I 3 5 - 110513860 29233923 MiREDiBase
A-to-I 4 5 - 110513859 29233923 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN26988089 5 COSMIC
COSN30456990 6 COSMIC
COSN15625252 6 COSMIC
COSN31522782 7 COSMIC
COSN31545996 8 COSMIC
COSN31570212 9 COSMIC
COSN1084275 12 COSMIC
COSN15625251 15 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs966876049 1 dbSNP
rs1321394893 2 dbSNP
rs923504759 3 dbSNP
rs1168522027 5 dbSNP
rs1187070531 5 dbSNP
rs1485986292 6 dbSNP
rs776299100 6 dbSNP
rs1421488925 6 dbSNP
rs748224431 6 dbSNP
rs1262049804 7 dbSNP
rs1258250226 7 dbSNP
rs568151991 8 dbSNP
rs1233367754 8 dbSNP
rs778777095 9 dbSNP
rs760758823 9 dbSNP
rs1330282349 10 dbSNP
rs749737324 10 dbSNP
rs760103713 10 dbSNP
rs754285569 10 dbSNP
rs756628155 10 dbSNP
rs1380895949 10 dbSNP
rs768673400 12 dbSNP
rs1478761955 13 dbSNP
rs1437534303 15 dbSNP
rs749009182 15 dbSNP
rs773271422 15 dbSNP
rs747569615 15 dbSNP
rs779944053 16 dbSNP
rs771761319 16 dbSNP
rs1159501553 18 dbSNP
rs757404662 19 dbSNP
rs1191871489 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol MPP5   
Synonyms PALS1
Description membrane palmitoylated protein 5
Transcript NM_022474   
Expression
Putative miRNA Targets on MPP5
3'UTR of MPP5
(miRNA target sites are highlighted)		 
>MPP5|NM_022474|3'UTR
   1 AAGAAACATCCATTCTGTGGCATGTTGGACTTGATCTGGCAAAAACTGCCAATAGGAGGACTGCCCGACACTGCAGCAAG
  81 ATTGAGGATAAGATGGAAGGCAGCAGTATAAGCTGTAGATCTGTTCTTAGATCTCTTGAATTAGTGAGACGACAGTTCCC
 161 TTAGGCAGTTTGTGCATGGCATCCTTTATTCTCTATACATGGCTTTAGCGGTTCTTGCCTCATTTTGGGATTCTAAATGG
 241 AAGCTTTCAACAGAGCATTCCATTTTGTCCTGTTAAAACCTTTTGTTTTCACCTAAACCCTTTCTGCTTAGTTGTATCTC
 321 TGTGAAAAACTTGTATACACAAGCGTCCATGTCTCACACAAATATTGATGTGATTATTCTTAAGTGTTAAATCATTAACA
 401 CTTAAATGACTTCATTGGGAATATTGAGCAGAGGGACTGTGCTTCTATGCACTGGGCAAGGCAGTATTTGCTTAGGAAAC
 481 TAATTTAGTCATCAGAGATACTTTCCTAAAAAGGAAAAATAAAAAACAAAATGGTGCCACTTTGGGTTGAAGCTACTTTG
 561 TTAGGCTTGAATTCATTTATATGTCTTTTGATTCTTAAAAAAACAAAAAACATTCCATTAGAAGCACCAGTTTTTTTGCT
 641 CAGACTTTGTGGATCAGACTCTACACTCAACACACTCTAATCTACTTAAAGGTATACAAAATATGCTGATCTTTTTTAAA
 721 TTATGATTTCCTGAATTTTTTTCTTAAGTCGTCTCAACTGATTTACTCACTTAGCTTCCCTTCCCTCATCAGCATAGTAT
 801 AATAGAATGTATGTTACATTTTTATGAATGGCAGGTGTTCATTATAATCTGTATTGACTTAAAAAGTTTCTTCCTCATGA
 881 TGCTAATAGTTTTTTGTATACATGGGAGGATAGCACATTTGACAGTTTTTGCATTTTTATGTATGAGCACAGTATCCTAT
 961 GACTGTGCTACGTATATATAGGTAATAAACTGGAATTCTGTTGATGAATATAGCTGCTGTACTGTATATTAATATTTAAT
1041 AGATCAACAAATGGTCATTGAAAACACTTGTTTAGCATTAGAATAAAATTATATATGTCCTTGGGAAATATTATGACAGT
1121 TGACTTTAAGATCAAAAGGAAGGGAAGACCTGAAAGTCATTTGAACATTTTAGGAAAAGAATATTGGAGAGAAAAAGGTA
1201 TTAAATATATAGAAATAGGTTTTTAACCTAACAAGGTCTGCCTCTTATGACGAGAATGCAACAGCTTGGTAAATCATAAA
1281 AGAAACATTTAAGCTAATAGGATTTTCGTACTGTCTCTATAGCTGTAGCTTTAAAATTCAACGTATATAATTGGCATGGA
1361 AACTTAATTTGCAGTCTTTTCAAGCCTTTAGGATAGTGTGATGTGTAACAAACAACCTCAAATGTGAATGCCTTGATTTT
1441 ATTTTTATGGTGACTTTAGCTACAGCATTTCCTATACCCAGAGCTAAACACTGGAATAATACTGACATCATTTAATTTAA
1521 CATAAGCAATTATGTTTAAGGAGTAATTTGTGTCATGTACATATTTGATTGATTTTTTTTCTTCTACATAATTTTATTTG
1601 AACAAATGTAGACAGTTTATATGTCGCCTTTTTCTGTTCAAATTTGCATGGCCTATTAAGTTGGCTGGAGAGTGTTTTAT
1681 GTGGAAATATTTTCAAGATAATGTTCCTTAGGAAGAAAATAACATTCTTGGGTTGAGGGAAGGAATGCCATACACTACTG
1761 TCTCTTCAGATCTGAAATACTCCAGTTTAGAGCCAGGAAATTTCACAGGTCACACCGATTTTTAGCATTAAAAACTAAGG
1841 AATATACTTAGCACTTACTTAATCTTTTCAGTTTTCCAGTTTACGTCTCAGGAATGAAGTGTAGTCTATGGTTGACAATG
1921 GAGTTTTGTGATCCTGCTTATTGTAACTGACAACTGTTTTCAACTCCAAGAGCTAAACTATTGGCAGTTCATGTTAAGTT
2001 AGAGTGAGGGTGTAGGTAGTGTCAGTGAGTGGCTCTTGTGCCTGCTGTAGACATTAGGCCTGCACTAGGGCCATGTGCTG
2081 TCAAGATTCAGGAACATGGCTTTAACAAGCAGATCTTGTATCAAGGCAGAGGTGATGCCATGCCATACTTTTAGGAAGTC
2161 TGAGATGATAAATATTTCAAGGTCAGTGAAGTCTATCAATCATTCTCCCCTTCCTCATCAGCAATGGTAGATAGAAATGT
2241 CCTAAACTTTTCTAAATCCTAGTGATGAGGATGTGCTGATATTCAACATAGTCCTTAAAGTGAAAACTGAGTTGTTGCTG
2321 ACCTCCACAAAAGAATATGGAAAAAAGCCTTGCTGTACACCTAGTTGTACAGCCACTCTGGCCAATTCCATTTCCTGTCC
2401 CTCTGTGGTTCTGACTGGAGACCCCAGTGTGGGGGAGGTCTTACCATTTAATATAGAAATGATATCAATAACTAATGCTA
2481 TGTACTTGGAAAATCCAAATAAGGAAGTTTTAGGTTGGTGCATAACTTTGTTTCTCAAATTTTCGTTGTCAGAACAAATG
2561 GAAGGAGAATATTATTTAGACTAATCCAGATTTGCTTTCTATGAAAATCTAATGTCTGGATTATCTTCCTTTTCTCATGG
2641 CCTAAGAAATAAGGATCAATAAGGAATGATTTGAATGTAATTTTGTGAATGTGTGGAAAATATAAAGCAGGGATTTAGCC
2721 TTAATAAAGGTAACCTTCTGACATCTGTTGTTAATCCCCCTTTGTACTCTTTTCCTGTATCTGCACTGTTATTTTGAGAT
2801 GTCATACTGTACACTGTATTGTAAAAATAAAAAGTAAAATTATATTTCAAATTTTAAAAGCCACTAAGCAATTTCTCTTG
2881 CTATTTGCTCGGCCACTCAAGGTTTCCACACATGTAAAGACCACCCTCCTCTTCAAGTTTTTGCCAAAAGCAAGACCATT
2961 GGATCCTCCAGCTACAACACAAAATACTTTTTGATTTGTTCTTTACAGAGGGATAGTGCCCCCTGTTGGCACAGGTATAG
3041 GTAGGTCCTGTTTCCTTAATTATTAAAACCAACAACTAAGTGTATTAAAGATGGACAACGCAAGG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuuUCAU-UAA--UGUCAAAAa 5'
             || | |||  |||||||| 
Target 5' gatAGCACATTTGACAGTTTTt 3'
 909 - 930 154.00 -7.30
2 
miRNA  3' uuuUCAUUAAUGUCAAAAa 5'
             || |:   ||||||| 
Target 5' attAGAAGCACCAGTTTTt 3'
 617 - 635 144.00 -6.00
3 
miRNA  3' uuuucAUUAAUGUCAAAAa 5'
               |: | |:|||||| 
Target 5' catgaTGCTAATAGTTTTt 3'
 876 - 894 134.00 -5.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30468007 12 COSMIC
COSN30680350 33 COSMIC
COSN30502440 46 COSMIC
COSN30728184 46 COSMIC
COSN30145069 67 COSMIC
COSN31557053 67 COSMIC
COSN1170303 80 COSMIC
COSN30516574 85 COSMIC
COSN29126417 92 COSMIC
COSN30166956 152 COSMIC
COSN25027717 188 COSMIC
COSN31517202 403 COSMIC
COSN31523723 425 COSMIC
COSN31482245 432 COSMIC
COSN31591055 638 COSMIC
COSN19657761 644 COSMIC
COSN26094766 906 COSMIC
COSN31490835 909 COSMIC
COSN31566447 938 COSMIC
COSN31531464 969 COSMIC
COSN22735953 1192 COSMIC
COSN26649389 1253 COSMIC
COSN31537643 1294 COSMIC
COSN17078445 1401 COSMIC
COSN21963606 1556 COSMIC
COSN31545266 1581 COSMIC
COSN31516351 1595 COSMIC
COSN24809662 1991 COSMIC
COSN25828755 2173 COSMIC
COSN31544555 2484 COSMIC
COSN30175068 2553 COSMIC
COSN6257110 2574 COSMIC
COSN31548032 2647 COSMIC
COSN20111410 2788 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1393698030 2 dbSNP
rs1026937943 5 dbSNP
rs1344412634 7 dbSNP
rs773256675 8 dbSNP
rs1289491802 16 dbSNP
rs199526528 18 dbSNP
rs753277440 24 dbSNP
rs1054534346 26 dbSNP
rs113964073 28 dbSNP
rs1164285950 30 dbSNP
rs1313599429 33 dbSNP
rs780592983 34 dbSNP
rs570677829 38 dbSNP
rs781365853 40 dbSNP
rs575116943 41 dbSNP
rs375898320 46 dbSNP
rs748419184 46 dbSNP
rs982223697 49 dbSNP
rs770078944 51 dbSNP
rs72717392 53 dbSNP
rs935554745 54 dbSNP
rs1022772885 67 dbSNP
rs549390014 68 dbSNP
rs1449495659 70 dbSNP
rs148258233 73 dbSNP
rs1275196231 74 dbSNP
rs528575692 77 dbSNP
rs1438414958 82 dbSNP
rs1329270276 89 dbSNP
rs1015236743 108 dbSNP
rs1325138745 112 dbSNP
rs571854808 119 dbSNP
rs1466151467 120 dbSNP
rs1034264684 123 dbSNP
rs1168740481 131 dbSNP
rs1409587526 141 dbSNP
rs889476474 147 dbSNP
rs547252678 151 dbSNP
rs1252856572 152 dbSNP
rs571716708 155 dbSNP
rs973676747 178 dbSNP
rs189230259 179 dbSNP
rs1457790702 185 dbSNP
rs1239437235 187 dbSNP
rs1196260980 193 dbSNP
rs1007830084 199 dbSNP
rs1278974478 200 dbSNP
rs1040839995 209 dbSNP
rs1342625312 210 dbSNP
rs1026694703 211 dbSNP
rs1447460356 220 dbSNP
rs1379090377 224 dbSNP
rs896889071 229 dbSNP
rs1441655499 230 dbSNP
rs994022589 251 dbSNP
rs1178521983 253 dbSNP
rs1279915256 257 dbSNP
rs1315823790 262 dbSNP
rs1218325097 268 dbSNP
rs759797123 269 dbSNP
rs1027195410 284 dbSNP
rs772044192 286 dbSNP
rs952625026 293 dbSNP
rs1263917302 294 dbSNP
rs1174969217 296 dbSNP
rs953799066 300 dbSNP
rs762217699 304 dbSNP
rs910710064 307 dbSNP
rs1486501968 312 dbSNP
rs557327484 315 dbSNP
rs775700989 319 dbSNP
rs1279300084 321 dbSNP
rs944978791 323 dbSNP
rs976356662 331 dbSNP
rs924637580 340 dbSNP
rs924085296 341 dbSNP
rs1477695642 346 dbSNP
rs956965069 349 dbSNP
rs934654594 350 dbSNP
rs1429479048 355 dbSNP
rs1304772363 362 dbSNP
rs1446053524 367 dbSNP
rs1054417143 373 dbSNP
rs1299171067 382 dbSNP
rs1421973429 387 dbSNP
rs1159030067 399 dbSNP
rs1417951806 402 dbSNP
rs1413926262 408 dbSNP
rs1183134340 412 dbSNP
rs1474014986 414 dbSNP
rs1256451957 415 dbSNP
rs1173396895 416 dbSNP
rs569523033 421 dbSNP
rs1489156478 424 dbSNP
rs536693956 425 dbSNP
rs73284818 436 dbSNP
rs773554333 448 dbSNP
rs1314916179 450 dbSNP
rs1050658652 458 dbSNP
rs1355053764 464 dbSNP
rs12590952 486 dbSNP
rs766561315 487 dbSNP
rs777405207 491 dbSNP
rs943739039 492 dbSNP
rs1284190993 497 dbSNP
rs1015473825 499 dbSNP
rs1352166240 501 dbSNP
rs1393282782 507 dbSNP
rs1385358273 521 dbSNP
rs897038664 521 dbSNP
rs995153743 524 dbSNP
rs1217656930 528 dbSNP
rs753865069 537 dbSNP
rs546453721 538 dbSNP
rs994300617 539 dbSNP
rs1048237322 544 dbSNP
rs566351386 546 dbSNP
rs1259366379 548 dbSNP
rs755065615 555 dbSNP
rs1026580428 556 dbSNP
rs888310439 568 dbSNP
rs2319776 569 dbSNP
rs764148023 574 dbSNP
rs1023599295 581 dbSNP
rs1219516738 582 dbSNP
rs1258894591 586 dbSNP
rs1261569772 594 dbSNP
rs1220728119 597 dbSNP
rs1341278011 602 dbSNP
rs985210785 604 dbSNP
rs1370277484 605 dbSNP
rs1387778363 605 dbSNP
rs751518133 611 dbSNP
rs1459370637 613 dbSNP
rs1018231086 629 dbSNP
rs1248792389 632 dbSNP
rs180828713 634 dbSNP
rs1031394296 641 dbSNP
rs960797 644 dbSNP
rs924857902 650 dbSNP
rs1468058162 658 dbSNP
rs1400718542 660 dbSNP
rs1200656081 661 dbSNP
rs1160399668 662 dbSNP
rs989997415 665 dbSNP
rs934873982 667 dbSNP
rs1418899210 674 dbSNP
rs1234351071 675 dbSNP
rs1491380481 675 dbSNP
rs1491332373 676 dbSNP
rs185664071 677 dbSNP
rs780843902 678 dbSNP
rs915305388 679 dbSNP
rs1448440207 683 dbSNP
rs1332581678 695 dbSNP
rs1466313683 701 dbSNP
rs575786779 702 dbSNP
rs1274478903 705 dbSNP
rs745619166 711 dbSNP
rs1380902559 718 dbSNP
rs986254772 718 dbSNP
rs912153373 720 dbSNP
rs944919363 723 dbSNP
rs1250023921 724 dbSNP
rs1374150223 724 dbSNP
rs1044483378 725 dbSNP
rs1484385158 736 dbSNP
rs907247565 738 dbSNP
rs540914411 745 dbSNP
rs113519869 751 dbSNP
rs1240486716 751 dbSNP
rs563476443 752 dbSNP
rs755727011 754 dbSNP
rs1310830342 765 dbSNP
rs995372934 765 dbSNP
rs1433937932 785 dbSNP
rs1361027718 786 dbSNP
rs888197064 801 dbSNP
rs947904155 809 dbSNP
rs1450236409 810 dbSNP
rs1188397472 812 dbSNP
rs1044888460 813 dbSNP
rs1245711145 816 dbSNP
rs1255759625 818 dbSNP
rs1210535058 833 dbSNP
rs906465755 834 dbSNP
rs530823597 835 dbSNP
rs1317244900 836 dbSNP
rs1003839601 843 dbSNP
rs779719077 855 dbSNP
rs1244956754 857 dbSNP
rs1179925877 858 dbSNP
rs5809339 859 dbSNP
rs3067315 860 dbSNP
rs34677658 861 dbSNP
rs892483136 861 dbSNP
rs1340930068 863 dbSNP
rs1320094214 866 dbSNP
rs748820413 878 dbSNP
rs1398861057 882 dbSNP
rs1384243090 884 dbSNP
rs1010904090 886 dbSNP
rs1163757196 890 dbSNP
rs1392695288 897 dbSNP
rs1415877521 900 dbSNP
rs1022370006 903 dbSNP
rs1265752670 905 dbSNP
rs1191548079 911 dbSNP
rs768134869 912 dbSNP
rs889453685 917 dbSNP
rs1209842826 918 dbSNP
rs1336338313 925 dbSNP
rs986264655 926 dbSNP
rs1019047395 932 dbSNP
rs1007088268 942 dbSNP
rs777225336 944 dbSNP
rs1428467922 946 dbSNP
rs1325719409 948 dbSNP
rs1324144676 959 dbSNP
rs1449243741 960 dbSNP
rs1164348040 964 dbSNP
rs1392410789 964 dbSNP
rs972756226 968 dbSNP
rs189444040 972 dbSNP
rs561252529 973 dbSNP
rs1247741252 979 dbSNP
rs532880876 983 dbSNP
rs965463791 983 dbSNP
rs1467558032 994 dbSNP
rs1250573701 997 dbSNP
rs1212591647 1002 dbSNP
rs753544514 1002 dbSNP
rs1274685100 1003 dbSNP
rs1286403777 1013 dbSNP
rs1338527791 1020 dbSNP
rs1354704132 1028 dbSNP
rs1275327810 1029 dbSNP
rs1236360868 1032 dbSNP
rs947747662 1034 dbSNP
rs1209565992 1039 dbSNP
rs1325285136 1041 dbSNP
rs1288741793 1042 dbSNP
rs1447697953 1045 dbSNP
rs1356426852 1046 dbSNP
rs997705120 1048 dbSNP
rs1409711629 1050 dbSNP
rs1200116242 1054 dbSNP
rs1426276095 1058 dbSNP
rs1031816593 1059 dbSNP
rs1235888280 1067 dbSNP
rs956305696 1068 dbSNP
rs906390675 1069 dbSNP
rs1188167359 1070 dbSNP
rs1192393064 1071 dbSNP
rs1457835042 1082 dbSNP
rs1370058177 1085 dbSNP
rs990382626 1093 dbSNP
rs1202040113 1094 dbSNP
rs914596496 1096 dbSNP
rs1162388176 1099 dbSNP
rs34674188 1103 dbSNP
rs1424048903 1109 dbSNP
rs1236289197 1118 dbSNP
rs970091282 1120 dbSNP
rs774882269 1122 dbSNP
rs200993498 1125 dbSNP
rs1052818736 1133 dbSNP
rs528614932 1135 dbSNP
rs1375644943 1140 dbSNP
rs892374887 1142 dbSNP
rs1044745 1143 dbSNP
rs1396621990 1144 dbSNP
rs1441723016 1146 dbSNP
rs928753585 1159 dbSNP
rs1360026145 1174 dbSNP
rs938738455 1174 dbSNP
rs1315179332 1179 dbSNP
rs1433256703 1184 dbSNP
rs1375315284 1195 dbSNP
rs1036853364 1198 dbSNP
rs1159811525 1199 dbSNP
rs562513539 1205 dbSNP
rs918399396 1211 dbSNP
rs765161622 1213 dbSNP
rs889217105 1213 dbSNP
rs1257870566 1219 dbSNP
rs1244658566 1230 dbSNP
rs1007570379 1232 dbSNP
rs1484575466 1233 dbSNP
rs1279459099 1252 dbSNP
rs750094696 1253 dbSNP
rs1217211118 1257 dbSNP
rs1318710713 1269 dbSNP
rs1282231787 1274 dbSNP
rs1223357835 1276 dbSNP
rs764927892 1283 dbSNP
rs1295366103 1290 dbSNP
rs1018972047 1295 dbSNP
rs931266965 1297 dbSNP
rs1048296671 1299 dbSNP
rs748765493 1301 dbSNP
rs966635651 1307 dbSNP
rs889670178 1308 dbSNP
rs1027018554 1309 dbSNP
rs1399619621 1309 dbSNP
rs1255685992 1311 dbSNP
rs1418051833 1314 dbSNP
rs1189653700 1318 dbSNP
rs1316763157 1320 dbSNP
rs1256515661 1323 dbSNP
rs1200477901 1329 dbSNP
rs1186949420 1341 dbSNP
rs1486805783 1343 dbSNP
rs1006562914 1344 dbSNP
rs1440682473 1346 dbSNP
rs1335577750 1348 dbSNP
rs1186740629 1349 dbSNP
rs1263721860 1354 dbSNP
rs952298234 1355 dbSNP
rs138017341 1360 dbSNP
rs1279217286 1369 dbSNP
rs909517189 1370 dbSNP
rs947685877 1374 dbSNP
rs1168813192 1377 dbSNP
rs753107688 1385 dbSNP
rs1429355625 1392 dbSNP
rs1394620084 1393 dbSNP
rs1166534811 1394 dbSNP
rs1459538366 1397 dbSNP
rs1423126567 1398 dbSNP
rs900935075 1406 dbSNP
rs1259516375 1407 dbSNP
rs1430100943 1407 dbSNP
rs1174430499 1411 dbSNP
rs773864381 1413 dbSNP
rs999264352 1422 dbSNP
rs1396019548 1433 dbSNP
rs1211960170 1436 dbSNP
rs1254939292 1436 dbSNP
rs1468199228 1443 dbSNP
rs1252112373 1451 dbSNP
rs1299339941 1453 dbSNP
rs532635018 1458 dbSNP
rs181721057 1461 dbSNP
rs1295445861 1462 dbSNP
rs956190245 1476 dbSNP
rs1011869400 1485 dbSNP
rs778282751 1486 dbSNP
rs541095242 1494 dbSNP
rs1298418431 1501 dbSNP
rs1463299227 1503 dbSNP
rs1371101719 1504 dbSNP
rs1454644664 1510 dbSNP
rs747463001 1510 dbSNP
rs970691631 1513 dbSNP
rs1396881700 1520 dbSNP
rs1191749672 1522 dbSNP
rs1233475686 1524 dbSNP
rs1251451353 1526 dbSNP
rs1197808640 1534 dbSNP
rs369875400 1545 dbSNP
rs980138397 1551 dbSNP
rs559781163 1552 dbSNP
rs569476809 1556 dbSNP
rs537095209 1562 dbSNP
rs1212130146 1565 dbSNP
rs372325482 1565 dbSNP
rs545227084 1565 dbSNP
rs1301900002 1566 dbSNP
rs1044749 1568 dbSNP
rs960136129 1569 dbSNP
rs1199812636 1572 dbSNP
rs1330037824 1572 dbSNP
rs1043721313 1573 dbSNP
rs1392754905 1573 dbSNP
rs143495052 1584 dbSNP
rs1297385485 1588 dbSNP
rs1435107295 1589 dbSNP
rs1489161509 1607 dbSNP
rs918451646 1608 dbSNP
rs1040476379 1610 dbSNP
rs1364425758 1614 dbSNP
rs201934706 1618 dbSNP
rs1262167649 1620 dbSNP
rs931159159 1622 dbSNP
rs112145248 1626 dbSNP
rs566893949 1627 dbSNP
rs1486871981 1634 dbSNP
rs1006504537 1642 dbSNP
rs1023202209 1654 dbSNP
rs1260785015 1656 dbSNP
rs969080582 1656 dbSNP
rs980424401 1666 dbSNP
rs1362947173 1670 dbSNP
rs1287336363 1672 dbSNP
rs927710300 1672 dbSNP
rs765374479 1673 dbSNP
rs1298011004 1702 dbSNP
rs942585118 1704 dbSNP
rs1387063909 1709 dbSNP
rs1310885125 1711 dbSNP
rs1434002238 1718 dbSNP
rs988398416 1721 dbSNP
rs1160307181 1725 dbSNP
rs1451740531 1740 dbSNP
rs913706140 1742 dbSNP
rs1302874826 1743 dbSNP
rs1188963511 1745 dbSNP
rs1476334372 1758 dbSNP
rs946540453 1758 dbSNP
rs1187756169 1759 dbSNP
rs1264481050 1760 dbSNP
rs1448073472 1760 dbSNP
rs1206320581 1761 dbSNP
rs879020669 1763 dbSNP
rs1347946158 1770 dbSNP
rs534415146 1771 dbSNP
rs147144654 1772 dbSNP
rs1336557385 1775 dbSNP
rs1355820433 1778 dbSNP
rs1447020791 1779 dbSNP
rs1214334014 1782 dbSNP
rs1320234043 1783 dbSNP
rs1380565807 1783 dbSNP
rs577658033 1789 dbSNP
rs1165815808 1791 dbSNP
rs910468028 1797 dbSNP
rs544921758 1807 dbSNP
rs1164571114 1812 dbSNP
rs557098745 1815 dbSNP
rs201125617 1817 dbSNP
rs901929748 1818 dbSNP
rs993575819 1820 dbSNP
rs1446971216 1823 dbSNP
rs1432692779 1824 dbSNP
rs1179286485 1828 dbSNP
rs1246856633 1830 dbSNP
rs745953524 1832 dbSNP
rs1469479270 1833 dbSNP
rs1438435482 1835 dbSNP
rs1270900075 1837 dbSNP
rs1227482881 1841 dbSNP
rs1158573033 1843 dbSNP
rs893521037 1848 dbSNP
rs1271759153 1853 dbSNP
rs1339870858 1853 dbSNP
rs1225129478 1856 dbSNP
rs1364448539 1857 dbSNP
rs1326663080 1858 dbSNP
rs1350841540 1861 dbSNP
rs751614395 1885 dbSNP
rs761642021 1886 dbSNP
rs778367536 1890 dbSNP
rs1006389687 1896 dbSNP
rs542910977 1896 dbSNP
rs1166565348 1900 dbSNP
rs1449379424 1901 dbSNP
rs906142525 1903 dbSNP
rs114884567 1909 dbSNP
rs186121940 1913 dbSNP
rs540732924 1919 dbSNP
rs1439667210 1940 dbSNP
rs775835049 1946 dbSNP
rs1035731982 1954 dbSNP
rs970263306 1955 dbSNP
rs767422143 1964 dbSNP
rs749844201 1973 dbSNP
rs972672022 1975 dbSNP
rs1034667808 1988 dbSNP
rs1193930292 1989 dbSNP
rs1025688720 1992 dbSNP
rs1304080797 1993 dbSNP
rs1341295377 1993 dbSNP
rs952777351 1998 dbSNP
rs987937246 1999 dbSNP
rs1443174771 2003 dbSNP
rs1322117103 2008 dbSNP
rs1246647572 2009 dbSNP
rs1356555342 2011 dbSNP
rs1361423843 2015 dbSNP
rs750218590 2020 dbSNP
rs967894613 2024 dbSNP
rs1176113486 2027 dbSNP
rs1044750 2044 dbSNP
rs1422421654 2052 dbSNP
rs942658274 2054 dbSNP
rs977073167 2056 dbSNP
rs779625105 2061 dbSNP
rs943251555 2063 dbSNP
rs976509822 2067 dbSNP
rs1280903268 2071 dbSNP
rs74765373 2092 dbSNP
rs553676827 2096 dbSNP
rs923270770 2097 dbSNP
rs934992213 2098 dbSNP
rs1277984156 2105 dbSNP
rs929278224 2111 dbSNP
rs753460021 2123 dbSNP
rs1278026487 2126 dbSNP
rs1409558437 2137 dbSNP
rs566544388 2140 dbSNP
rs746402450 2140 dbSNP
rs887852059 2142 dbSNP
rs1368234452 2146 dbSNP
rs139455369 2147 dbSNP
rs942181877 2150 dbSNP
rs1460651104 2154 dbSNP
rs893572922 2159 dbSNP
rs1359165473 2161 dbSNP
rs1331604354 2163 dbSNP
rs549538165 2164 dbSNP
rs1409637283 2166 dbSNP
rs1156548815 2168 dbSNP
rs1443863765 2168 dbSNP
rs746080780 2169 dbSNP
rs772355822 2170 dbSNP
rs1257942290 2172 dbSNP
rs1189876907 2178 dbSNP
rs1297561588 2180 dbSNP
rs946445199 2183 dbSNP
rs550926350 2185 dbSNP
rs1236839684 2194 dbSNP
rs1397678739 2194 dbSNP
rs1043253085 2195 dbSNP
rs1310371232 2195 dbSNP
rs188878222 2199 dbSNP
rs906022513 2204 dbSNP
rs760632293 2209 dbSNP
rs1219489127 2225 dbSNP
rs1227991907 2228 dbSNP
rs1335797693 2228 dbSNP
rs181357014 2228 dbSNP
rs1295492038 2230 dbSNP
rs1413323074 2231 dbSNP
rs1379003227 2233 dbSNP
rs1289995709 2238 dbSNP
rs1035909801 2241 dbSNP
rs896030178 2248 dbSNP
rs1003098007 2258 dbSNP
rs994149411 2259 dbSNP
rs1456368040 2268 dbSNP
rs1316172834 2269 dbSNP
rs1203864762 2271 dbSNP
rs12435297 2274 dbSNP
rs566931716 2283 dbSNP
rs984594843 2289 dbSNP
rs1018147116 2290 dbSNP
rs1187003364 2294 dbSNP
rs1486834489 2296 dbSNP
rs1246248027 2298 dbSNP
rs964213427 2303 dbSNP
rs1208259824 2308 dbSNP
rs1469021707 2309 dbSNP
rs1020737688 2318 dbSNP
rs1242999687 2319 dbSNP
rs976579000 2320 dbSNP
rs190925914 2323 dbSNP
rs1319779369 2324 dbSNP
rs12887166 2330 dbSNP
rs12887167 2332 dbSNP
rs1478314462 2336 dbSNP
rs1360563701 2348 dbSNP
rs1294762924 2358 dbSNP
rs1170962787 2359 dbSNP
rs1425264461 2362 dbSNP
rs376664307 2362 dbSNP
rs1327537821 2369 dbSNP
rs967738868 2374 dbSNP
rs1349066862 2379 dbSNP
rs1170953810 2380 dbSNP
rs12887486 2396 dbSNP
rs922531381 2400 dbSNP
rs1169178972 2404 dbSNP
rs1388252226 2406 dbSNP
rs979239406 2410 dbSNP
rs1359211413 2421 dbSNP
rs1017370040 2423 dbSNP
rs964613947 2424 dbSNP
rs369198685 2425 dbSNP
rs1300946157 2427 dbSNP
rs1252241433 2438 dbSNP
rs1207151240 2439 dbSNP
rs750036097 2439 dbSNP
rs1400334112 2442 dbSNP
rs1297530298 2443 dbSNP
rs923176284 2444 dbSNP
rs929355922 2455 dbSNP
rs1305053740 2458 dbSNP
rs1384700414 2460 dbSNP
rs1366547208 2468 dbSNP
rs1280373920 2469 dbSNP
rs866299133 2469 dbSNP
rs1298464900 2472 dbSNP
rs1463341832 2480 dbSNP
rs1368573744 2484 dbSNP
rs1167912799 2486 dbSNP
rs571283433 2489 dbSNP
rs1396948628 2498 dbSNP
rs113916335 2501 dbSNP
rs1196924672 2505 dbSNP
rs538712596 2512 dbSNP
rs1251524190 2522 dbSNP
rs1179262156 2523 dbSNP
rs1482291760 2523 dbSNP
rs1274421480 2526 dbSNP
rs1279497037 2527 dbSNP
rs1314020026 2536 dbSNP
rs914891300 2545 dbSNP
rs1257237638 2546 dbSNP
rs1280172143 2553 dbSNP
rs1311188038 2557 dbSNP
rs946524765 2559 dbSNP
rs150069132 2567 dbSNP
rs1348366015 2570 dbSNP
rs1196248553 2574 dbSNP
rs1307240776 2577 dbSNP
rs879007550 2580 dbSNP
rs1415312142 2581 dbSNP
rs926356689 2590 dbSNP
rs1170827786 2591 dbSNP
rs1044597095 2593 dbSNP
rs1364552276 2597 dbSNP
rs1161596249 2602 dbSNP
rs1261438603 2604 dbSNP
rs937506480 2604 dbSNP
rs906059304 2605 dbSNP
rs1486900685 2614 dbSNP
rs1254698660 2619 dbSNP
rs1198178100 2620 dbSNP
rs1343708875 2627 dbSNP
rs867612571 2639 dbSNP
rs1260841157 2641 dbSNP
rs778384933 2655 dbSNP
rs1057207170 2656 dbSNP
rs1326713736 2657 dbSNP
rs938830821 2660 dbSNP
rs896087477 2672 dbSNP
rs1342134700 2674 dbSNP
rs747596076 2678 dbSNP
rs1332142189 2681 dbSNP
rs994368097 2689 dbSNP
rs1047077894 2690 dbSNP
rs1290768380 2692 dbSNP
rs1455837897 2695 dbSNP
rs888444095 2704 dbSNP
rs1009243740 2708 dbSNP
rs1476402821 2712 dbSNP
rs1367190048 2714 dbSNP
rs1005670215 2725 dbSNP
rs1020540003 2731 dbSNP
rs1448131450 2745 dbSNP
rs1018784175 2746 dbSNP
rs1374733471 2755 dbSNP
rs1261805190 2770 dbSNP
rs1420204326 2770 dbSNP
rs1299860005 2772 dbSNP
rs964122247 2778 dbSNP
rs1000544136 2786 dbSNP
rs3840819 2786 dbSNP
rs397841625 2786 dbSNP
rs1214039525 2793 dbSNP
rs575484206 2797 dbSNP
rs1358241914 2802 dbSNP
rs998440494 2803 dbSNP
rs1017297293 2806 dbSNP
rs866177335 2807 dbSNP
rs536555547 2810 dbSNP
rs182756136 2813 dbSNP
rs1369834676 2815 dbSNP
rs1217497150 2817 dbSNP
rs988053573 2822 dbSNP
rs1433004581 2825 dbSNP
rs976311194 2831 dbSNP
rs1303352546 2837 dbSNP
rs3840820 2840 dbSNP
rs542835569 2840 dbSNP
rs1476027194 2843 dbSNP
rs983489075 2856 dbSNP
rs914943476 2865 dbSNP
rs373029903 2874 dbSNP
rs1447157238 2875 dbSNP
rs1246988741 2879 dbSNP
rs377078803 2882 dbSNP
rs1213897167 2884 dbSNP
rs926381787 2890 dbSNP
rs939088866 2891 dbSNP
rs1057261089 2892 dbSNP
rs1209024660 2899 dbSNP
rs963360212 2912 dbSNP
rs542426177 2914 dbSNP
rs1276712310 2923 dbSNP
rs1226221830 2924 dbSNP
rs1364501981 2925 dbSNP
rs1446781230 2929 dbSNP
rs1438864567 2930 dbSNP
rs980205739 2930 dbSNP
rs540294390 2935 dbSNP
rs927359584 2938 dbSNP
rs917399191 2939 dbSNP
rs565265174 2957 dbSNP
rs1246880633 2958 dbSNP
rs1410894613 2960 dbSNP
rs1372897881 2961 dbSNP
rs930268453 2972 dbSNP
rs879914314 2980 dbSNP
rs938897229 2983 dbSNP
rs1047296797 2993 dbSNP
rs1191337873 2994 dbSNP
rs1478768855 2999 dbSNP
rs551083573 2999 dbSNP
rs888671835 3003 dbSNP
rs41285538 3007 dbSNP
rs1160380366 3012 dbSNP
rs1438211667 3017 dbSNP
rs1039679191 3026 dbSNP
rs1253754759 3027 dbSNP
rs1202905549 3029 dbSNP
rs1341435005 3030 dbSNP
rs1281127443 3035 dbSNP
rs1221025504 3036 dbSNP
rs899945072 3046 dbSNP
rs1343069451 3048 dbSNP
rs1274511308 3052 dbSNP
rs1352682918 3064 dbSNP
rs913488485 3071 dbSNP
rs946268982 3079 dbSNP
rs1042051801 3080 dbSNP
rs114307487 3082 dbSNP
rs1029540249 3086 dbSNP
rs1171604485 3088 dbSNP
rs562744027 3093 dbSNP
rs1284745608 3096 dbSNP
rs1179835896 3098 dbSNP
rs1482652182 3100 dbSNP
rs1324482438 3101 dbSNP
rs1212274810 3106 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 64398.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000261681.4 | 3UTR | AAUAUACUUAGCACUUACUUAAUCUUUUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
STAD 0.689 0.26 0.500 0.33 3 Click to see details
UCEC -0.65 0.27 -1.000 0.5 3 Click to see details
LUSC -0.591 0.3 -1.000 0.5 3 Click to see details
HNSC 0.328 0.34 0.200 0.4 4 Click to see details
THCA -0.307 0.35 0.000 0.5 4 Click to see details
BLCA 0.041 0.49 0.500 0.33 3 Click to see details
BLCA 0.041 0.49 0.500 0.33 3 Click to see details
BLCA 0.041 0.49 0.500 0.33 3 Click to see details
BLCA 0.041 0.49 0.500 0.33 3 Click to see details
BLCA 0.041 0.49 0.500 0.33 3 Click to see details
BLCA 0.041 0.49 0.500 0.33 3 Click to see details
BLCA 0.041 0.49 0.500 0.33 3 Click to see details
153 hsa-miR-548f-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT075032 DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 2 2
MIRT076422 PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 2 2
MIRT077732 ZNF652 zinc finger protein 652 2 2
MIRT097425 JMY junction mediating and regulatory protein, p53 cofactor 2 2
MIRT099605 ID4 inhibitor of DNA binding 4, HLH protein 2 4
MIRT105530 ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 2 2
MIRT109834 MID1IP1 MID1 interacting protein 1 2 8
MIRT132952 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT134169 KLHL42 kelch like family member 42 2 4
MIRT138721 MPP5 membrane palmitoylated protein 5 2 2
MIRT187755 ESYT1 extended synaptotagmin 1 2 2
MIRT208054 LRRC58 leucine rich repeat containing 58 2 2
MIRT222029 PURB purine rich element binding protein B 2 2
MIRT243457 LMLN leishmanolysin like peptidase 2 2
MIRT266062 FJX1 four jointed box 1 2 6
MIRT279835 ZFP36L1 ZFP36 ring finger protein like 1 2 2
MIRT285122 TERF2IP TERF2 interacting protein 2 6
MIRT323906 TMEM245 transmembrane protein 245 2 2
MIRT325430 CKS2 CDC28 protein kinase regulatory subunit 2 2 2
MIRT338909 HMGN2 high mobility group nucleosomal binding domain 2 2 6
MIRT350498 MRGBP MRG domain binding protein 2 6
MIRT405877 CALM1 calmodulin 1 2 2
MIRT442081 NDRG1 N-myc downstream regulated 1 2 2
MIRT442371 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT442397 ILDR1 immunoglobulin like domain containing receptor 1 2 2
MIRT444255 INTS8 integrator complex subunit 8 2 2
MIRT444875 ISPD isoprenoid synthase domain containing 2 2
MIRT445407 PTCHD1 patched domain containing 1 2 4
MIRT445493 HMGN4 high mobility group nucleosomal binding domain 4 2 2
MIRT446136 ST6GAL2 ST6 beta-galactoside alpha-2,6-sialyltransferase 2 2 2
MIRT446261 GRAMD1C GRAM domain containing 1C 2 2
MIRT446353 EML6 echinoderm microtubule associated protein like 6 2 2
MIRT446403 SNX1 sorting nexin 1 2 2
MIRT446826 STK17A serine/threonine kinase 17a 2 2
MIRT447222 ABI2 abl interactor 2 2 2
MIRT447705 ERP44 endoplasmic reticulum protein 44 2 2
MIRT448248 ZNF774 zinc finger protein 774 2 2
MIRT448819 FKBP1A FK506 binding protein 1A 2 4
MIRT449060 ZNF558 zinc finger protein 558 2 2
MIRT449668 ZNF451 zinc finger protein 451 2 2
MIRT449974 ZNF555 zinc finger protein 555 2 2
MIRT450476 TRMT5 tRNA methyltransferase 5 2 4
MIRT450483 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT467980 SKIL SKI like proto-oncogene 2 4
MIRT470733 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT475012 KANSL1 KAT8 regulatory NSL complex subunit 1 2 8
MIRT490478 FEM1C fem-1 homolog C 2 2
MIRT497368 DIRAS2 DIRAS family GTPase 2 2 2
MIRT497561 PRLR prolactin receptor 2 2
MIRT497943 ABCB7 ATP binding cassette subfamily B member 7 2 2
MIRT498014 ZBTB20 zinc finger and BTB domain containing 20 2 2
MIRT498206 ACVR2B activin A receptor type 2B 2 2
MIRT502637 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT505633 SLC16A1 solute carrier family 16 member 1 2 6
MIRT512261 ARPP19 cAMP regulated phosphoprotein 19 2 6
MIRT518247 SCIN scinderin 2 4
MIRT520483 TRIM13 tripartite motif containing 13 2 4
MIRT521196 SBNO1 strawberry notch homolog 1 2 6
MIRT522764 LARP1 La ribonucleoprotein domain family member 1 2 4
MIRT525021 ABHD13 abhydrolase domain containing 13 2 4
MIRT525100 FRK fyn related Src family tyrosine kinase 2 2
MIRT525268 CD226 CD226 molecule 2 4
MIRT528662 FUNDC2 FUN14 domain containing 2 2 2
MIRT529353 SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 2 2
MIRT529651 ZNF81 zinc finger protein 81 2 2
MIRT529815 TMLHE trimethyllysine hydroxylase, epsilon 2 2
MIRT530316 TNFRSF10D TNF receptor superfamily member 10d 2 2
MIRT532775 LDHD lactate dehydrogenase D 2 2
MIRT533888 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT535657 NLN neurolysin 2 4
MIRT536351 LEFTY1 left-right determination factor 1 2 2
MIRT538089 DGKE diacylglycerol kinase epsilon 2 2
MIRT538118 DDX6 DEAD-box helicase 6 2 2
MIRT538950 BMP2K BMP2 inducible kinase 2 2
MIRT539086 ARNTL aryl hydrocarbon receptor nuclear translocator like 2 4
MIRT539374 ADSS adenylosuccinate synthase 2 6
MIRT539860 DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 2 4
MIRT539976 SPRY1 sprouty RTK signaling antagonist 1 2 2
MIRT541264 GPC4 glypican 4 2 4
MIRT543374 CYB5B cytochrome b5 type B 2 2
MIRT543472 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT543685 HHLA1 HERV-H LTR-associating 1 2 2
MIRT543877 SLC16A9 solute carrier family 16 member 9 2 2
MIRT544021 KLRC3 killer cell lectin like receptor C3 2 2
MIRT544119 TTLL11 tubulin tyrosine ligase like 11 2 4
MIRT545311 SPC25 SPC25, NDC80 kinetochore complex component 2 2
MIRT545769 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT545991 XKR4 XK related 4 2 2
MIRT546078 VEZF1 vascular endothelial zinc finger 1 2 2
MIRT546717 RNPS1 RNA binding protein with serine rich domain 1 2 4
MIRT548964 CCNT2 cyclin T2 2 2
MIRT552133 MED10 mediator complex subunit 10 2 2
MIRT553941 STARD3NL STARD3 N-terminal like 2 2
MIRT554148 SLX4 SLX4 structure-specific endonuclease subunit 2 2
MIRT555009 RAB33B RAB33B, member RAS oncogene family 2 2
MIRT555495 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT555651 PHF12 PHD finger protein 12 2 2
MIRT557631 GJD3 gap junction protein delta 3 2 2
MIRT557989 FAM160B1 family with sequence similarity 160 member B1 2 2
MIRT558838 CDCA4 cell division cycle associated 4 2 4
MIRT563344 RPLP0 ribosomal protein lateral stalk subunit P0 2 2
MIRT563902 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT564263 DEPDC1B DEP domain containing 1B 2 2
MIRT565516 SOX4 SRY-box 4 2 2
MIRT565847 SCML2 Scm polycomb group protein like 2 2 2
MIRT567174 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT573142 ABT1 activator of basal transcription 1 2 2
MIRT573248 ZBTB46 zinc finger and BTB domain containing 46 2 2
MIRT573740 KHSRP KH-type splicing regulatory protein 2 2
MIRT573983 DDX21 DExD-box helicase 21 2 2
MIRT574478 RPS16 ribosomal protein S16 2 2
MIRT608343 ZRANB1 zinc finger RANBP2-type containing 1 2 2
MIRT609782 NHSL1 NHS like 1 2 2
MIRT612536 RSF1 remodeling and spacing factor 1 2 2
MIRT613193 CLOCK clock circadian regulator 2 2
MIRT617539 GRK4 G protein-coupled receptor kinase 4 2 2
MIRT617779 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT620252 PCK1 phosphoenolpyruvate carboxykinase 1 2 2
MIRT621740 TNPO2 transportin 2 2 2
MIRT628105 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT629471 CRLS1 cardiolipin synthase 1 2 6
MIRT638139 TTC26 tetratricopeptide repeat domain 26 2 2
MIRT641039 PITPNB phosphatidylinositol transfer protein beta 2 2
MIRT642453 CLUAP1 clusterin associated protein 1 2 2
MIRT643159 NCK1 NCK adaptor protein 1 2 2
MIRT643260 ZNF566 zinc finger protein 566 2 2
MIRT649827 LIPG lipase G, endothelial type 2 2
MIRT651199 ZNF280B zinc finger protein 280B 2 2
MIRT654633 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2 2
MIRT656633 LRRC15 leucine rich repeat containing 15 2 2
MIRT660588 APP amyloid beta precursor protein 2 2
MIRT660865 AFAP1 actin filament associated protein 1 2 2
MIRT664141 ATP6V1G3 ATPase H+ transporting V1 subunit G3 2 2
MIRT666130 SPATS2L spermatogenesis associated serine rich 2 like 2 2
MIRT666391 SHMT1 serine hydroxymethyltransferase 1 2 2
MIRT667143 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT673834 SPPL2A signal peptide peptidase like 2A 2 2
MIRT675539 KIAA1715 lunapark, ER junction formation factor 2 2
MIRT693450 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 2 2
MIRT694852 KRT80 keratin 80 2 2
MIRT696047 KCNK6 potassium two pore domain channel subfamily K member 6 2 2
MIRT696951 CERK ceramide kinase 2 2
MIRT697839 UBL3 ubiquitin like 3 2 2
MIRT700270 RAP2B RAP2B, member of RAS oncogene family 2 2
MIRT702733 INSIG1 insulin induced gene 1 2 2
MIRT705310 AVL9 AVL9 cell migration associated 2 2
MIRT705325 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 2 2
MIRT707735 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT711798 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT713736 SUCO SUN domain containing ossification factor 2 2
MIRT715766 SKA2 spindle and kinetochore associated complex subunit 2 2 2
MIRT719186 KCNS2 potassium voltage-gated channel modifier subfamily S member 2 2 2
MIRT719478 PECR peroxisomal trans-2-enoyl-CoA reductase 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-548f 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-548f-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-548f-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (WM266) (1uM)
hsa-miR-548f-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (WM266) (200nM)
hsa-miR-548f-3p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (WM266) (200nM)
hsa-miR-548f-3p Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (WM266) (500nM)
hsa-miR-548f-3p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (WM266) (1uM)
hsa-miR-548f-3p Trametinib 11707110 NSC758246 approved sensitive High Melanoma cell line (WM266) (500nM)
hsa-miR-548f-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-548f-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-548f-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-548f-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-548f-3p Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-548f-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-548f-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

Error report submission