| pre-miRNA Information | |
|---|---|
| pre-miRNA | hsa-mir-548x |
| Genomic Coordinates | chr21: 18686090 - 18686164 |
| Description | Homo sapiens miR-548x stem-loop |
| Comment | None |
| RNA Secondary Structure |  |
| Mature miRNA Information | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mature miRNA | hsa-miR-548x-5p | |||||||||||||||
| Sequence | 8| UGCAAAAGUAAUUGCAGUUUUUG |30 | |||||||||||||||
| Evidence | Not_experimental | |||||||||||||||
| Experiments | ||||||||||||||||
| SNPs in miRNA |
|
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| Putative Targets | ||||||||||||||||
| Gene Information | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene Symbol | BTF3L4 | ||||||||||||||||||||
| Synonyms | - | ||||||||||||||||||||
| Description | basic transcription factor 3 like 4 | ||||||||||||||||||||
| Transcript | NM_001136497 | ||||||||||||||||||||
| Other Transcripts | NM_152265 | ||||||||||||||||||||
| Expression | |||||||||||||||||||||
| Putative miRNA Targets on BTF3L4 | |||||||||||||||||||||
| 3'UTR of BTF3L4 (miRNA target sites are highlighted) |
>BTF3L4|NM_001136497|3'UTR 1 AAGTTTGGTTTTTGGAAGCTGGCATGGACTAGATTTAACAAATCAGCTATGTGGTTCCAAAGTTTTACAGACATGGAGAA 81 CATCACCTGTTACTAGTTCAGTAATATAAATATTTTGTATATTAATAATGCTGTTTGTTCAGCATTTTTCGGTCATTTGA 161 TTTTGCATTTTGCACTTCCTCCCAGGATATTTTTTTGGTCAAAATATGAAGTATTGGTGCAGTTTGAGGGTGTTTTGGTT 241 TTTGATTCCTGGTTTTTTTGTTTTTTGTTTGGGGTATTTTTGGTGTATGTATGTTTATGTATGTGTGTGGGTATGTGTGT 321 ATACAGTGGAGAGCAAATTGGAAAACAGTTCTATTTATCCTCCTCCCTCCCCAGTAGAAATAAAAAAAATCTTTACATTT 401 GTTACTTTTCTTTTCCCCCCGTAAGACACAGAATTAATGGAAAGTGAGTATCTTGGATTTCAAATCTGAAGAGATTTTTA 481 CCATTAGTGGTTTGATTTTAATTTGCTTGGTTAACTATCATATTTTTCATACACTTCTCTGGATTTAAAATATCTTGAGG 561 TATTTTGCCACTGGCTTCATGCTGGAGTAATGGGTAACATATCTTTGGTATGGTTGCCTTAGATTAACTTACCTAGTCAG 641 ACCCAGAAGAACTTCTTTTACTAGCTTGCTTCCTAAATGCCTTTTTTCCTCTCCTTTTGGTCTCCAAATGGCCTGGTCAG 721 CTTTTGGTAATATTCTTCCTCATCTTCCACCTAGCTTGAGAAGGATGTTCTCCATATAGAGTTTAGCGAGTGCCTAATCC 801 CTCCTTTTGTAAGATTTTGTTCCCTCAGCTTGAGGAACAACTTCATCTTCAACTTTTTATTTCTCCCTGATGTTACAGTT 881 TGGTAGATTTCAAACTGGAATAGCTAGCATGTGCTTGCTAAATAATTTTATGCCAGCCTTATCCTGTATCCTAGCTGTTC 961 TTAACAGCAGGTACAAAAATGCCTGTTTTTCAGCAAGGTTGAAATTGGGAATGTCCTTTTGAATCAGAAGAAAATAGGCC 1041 ATAGACTCATCTCCCAGCACAAATGGGCATTCTATGAAATGGTACTGGCCCTAGGAGGATTTCCTCAACCACTCTCCTAC 1121 TCTTGGCCTTGAACCTACCTCTGGGTTGGATCTTACTATTGTAGCTGCTCACTATACCCTCCTGCATGCTTAGAATAATG 1201 CTTTGAGGGGAGCACTGGTAAAACACAGTATTTATTTTTTTACCTCCTTTAAGAGGACTTGGAGGTAAGTTGCATTCATT 1281 CACTCAAGTTTCCCTCTTGCTGTCTAATAGAAGCTTACTTTTTGCTATATCAGCATTTGTTACAGCCAATATTTAAGGAC 1361 AAAATTTAGAAAATATATCATTTCCTGGCCCATCATCAAACTAATACAGCTTAACCTTGCAGCTACCAACTTTTGTGTCA 1441 AGCTAGATATCTTTATTTGATATCTAAGGTGCAAGACCAACAATATATTAAGAGATCTGTAGACATGAAGGCAAAGCTCT 1521 TGTATTTTTTTTCATCCAAACACCTCAATTTATTTTATAAATTCGTTCATTTTTCCTGTTATGTTTTATATAATATATGG 1601 ACTAAACAAAATAAAATAACAGTGCAAAAGAGGAGAATATTTCCTCTTGTGCTTTTCTTGATGTTGTGTACAGAATTTCC 1681 TTTTATATTATTCCTCTACCCTCCACCTGTAAATGAATGTTAGTGCAGTAATTGTTTGAAATAATGCCTCATCCAGTGTT 1761 AGGTCAGTAGCTCCACAGTCTACACAGTCCAGAATTCTTTCTCTAATTGTCCCAAAGGGGGACATTGTGGAGGCAGAGTT 1841 AGGGGGAACCACTTCAAGTGGTTAGGGACAGATAAATAATAGGCAGTATAGCACATGAAAGAAAACACACACTTGGAAGC 1921 CAGGAGACTTGTGTCCTAGTCAAAACTCTGGCATTATGTGACCTTGGACAGGTCATCTAACTACTCTGAAATTTATCATC 2001 AGTCAAATAAGATTTTATTCTGTTTTGTTTTGTTTGAGATGGGGATTTGCTCTTGTTGTCCAGGCCGAACTGCAATGTTG 2081 TGGTCTCGGCTGACTGCAACCTCCACCTCCCAGATTCAAGCGATTCTCCTGTCTCAGCCTCCACAGTAGCTGGGATTTTT 2161 TTTTTTTTTTTTTGTATTTTTAGTAGAGATGGGGTTTTACCATGTTGCCCAGGCCGGTCTTGAATTCCTGTCCTCAGGTG 2241 ATTCATTTGCCTCGGCCTCCCAAAGTGCTAGGATTACAGGCGTGAGCCACTGCACCCAGCCCAAATGAGATGTTTCTAAA 2321 TCTAAAGTTTCTTCTGCTTCTGCATTTCTGTGAATCTCATTTGAAATTTTTCAGGGAAGGGATTTTATCATTTGTTCAGA 2401 GATGTCTTTATTTTTATTAATACCCATAAAACGTTTGTGTATTTGCTTCTTCCTCTTTCTCCTTTTGATCACATTTTAGC 2481 TACTTATCTAGAGGATCTCTGGCCAAGTATTCCCTTTTATTGTATTGATAACAATTCTTAATGGCTGGCCTCTCTTGTGT 2561 ACAATGAGCCAATATTCTTTTTTGTTCTATATTTTTGTATCTTCCCCTTTCCTGAACAAAGCATATTTAGAGTCTCAAAG 2641 AAATCCTCTCCACAAAGACATGTTCCTCCCTCTGGTGTGGGTAGACATAGGGTAAGAGTTTGGATGAAACTTTTGTAAAT 2721 TGTAGTGTTCTTGGCATAAATATGAATTAAATCTTTTTTTATATTTAAATAACTAGTTAAATATGTGCTTCTTACTAAGA 2801 TTAGGTATTTTTTGCCAAGATAACAATGATAAAAACATTTTGGGGGGGAAATTGACCTTAAAATTTTGGGATAATTCAAG 2881 AAATGTCTGCAGAAAATTGATTTATGATCTTAATTTTTGTGTTAGTCCTTTGAGGTTTTTTTGTTTTTGTTTTTGTTCTT 2961 TGTAAAGCGCCTTATCTGTTTTGGACAAGTCCAAAGTAAATGGTTGGGCTCTTATATCTGTTTTACCCTTATTTTTCCCA 3041 TTAAGTAATGGTTTAAGAATATATCAAGCACCTTAATTTGTTGTTAAGTAGCTAGTGCTTACAGGATTCCATTAAATTCA 3121 CTTTAATAAGCCTATGAAGTTCTTATGAAAAACCCATATCTGCGATATGTTTGATTTGTTTCTTTGTTTTAATTCAGTGT 3201 TTAACCCTAGGTATGCTACATACCCATAAATAAGATACCATGGTAAGAGATAGTATGTTATAGTGGGAAAAGCACAAGTT 3281 TTTAGATAGAGATCAATTCTGCTATCTACCCTTACATTGTAACCTTTCTGACAGGGCTGCTGCGGTGCACAACTTCGGGA 3361 GCCATCACTTATTTTTGTTGTGTTCCAGAAGGTGTCATTTTCATAGACTGCAGTGTGAATAGTGTCCTCCATTAATAATG 3441 CAATGATGGCCTTGCTCTCTGAGCCTCAGTTTTATCTATAAAATGGTACCTAGAAGAGTCATGATTTCTTAGAATCCCCT 3521 AAATTATTAAGGTGAAGGTAGAAGATGATTAAAGCGTGTTATCTCCTAAGCTATGGCTTAGATTTTCCGAAGCTCATGGT 3601 TCTAGGCACAGAAAGTCTCCATTCTACACTGCATTTCAACCTGTGTTGAACAACACTCCAGTTCAGCCTGTATTGCTATG 3681 CCACATAGAGTTTGCCTGAATTATTATAGCTTTCTTAATAGTTTTGTTTATGATCCACTCTCTCCAGCCCATTACACAGG 3761 AGCCAGCTACCTAAATTTCCTATCTGAGCATGTCCTTACATTTACTTCCAGCATACTATTCATTTGCCATAGTAGAGTAT 3841 TAAGATTATTTGATTTTCTTTTTACTTTCTCGTAGTGCCCAATGTGTAGTTTACTCAACATCATAATATGTAATGTTTTT 3921 CAACTACTTACTGTTGAATACAAAGTTATCTCATTTAA Target sites
Provided by authors
Predicted by miRanda
DRVs
SNPs
DRVs & SNPs
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| miRNA-target interactions (Predicted by miRanda) |
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| DRVs in gene 3'UTRs | |||||||||||||||||||||
| SNPs in gene 3'UTRs | |||||||||||||||||||||
| Experimental Support 1 for Functional miRNA-Target Interaction | |||||||
|---|---|---|---|---|---|---|---|
| miRNA:Target | ---- | ||||||
| Validation Method |
|
||||||
| Conditions | HEK293 | ||||||
| Location of target site | 3'UTR | ||||||
| Tools used in this research | TargetScan , miRTarCLIP , Piranha | ||||||
| Original Description (Extracted from the article) |
...
PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control
PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control
PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection
... - Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell. |
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| miRNA-target interactions (Provided by authors) |
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| Article |
- Hafner M; Landthaler M; Burger L; Khorshid et al. - Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
|
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| Experimental Support 2 for Functional miRNA-Target Interaction | |
|---|---|
| miRNA:Target | ---- |
| Validation Method |
|
| Conditions | HEK293 |
| Disease | 91408.0 |
| Location of target site | 3'UTR |
| Tools used in this research | TargetScan , miRTarCLIP , Piranha |
| Original Description (Extracted from the article) |
...
"PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1
... - Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods. |
| Article |
- Kishore S; Jaskiewicz L; Burger L; Hausser et al. - Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
|
| Experimental Support 3 for Functional miRNA-Target Interaction | |
|---|---|
| miRNA:Target | ---- |
| Validation Method |
|
| Conditions | C8166 |
| Location of target site | 3'UTR |
| Tools used in this research | TargetScan , miRTarCLIP , Piranha |
| Original Description (Extracted from the article) |
...
PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3
... - Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio. |
| Article |
- Whisnant AW; Bogerd HP; Flores O; Ho P; et al. - mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
|
| CLIP-seq Support 1 for dataset GSM545212 | |
|---|---|
| Method / RBP | PAR-CLIP / AGO1 |
| Cell line / Condition | HEK293 / Control |
| Location of target site | ENST00000489308.2 | 3UTR | AUUUUGCAUUUUGCACUUCCUCCCAG |
| Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
| Article / Accession Series | PMID: 20371350 / GSE21578 |
| CLIP-seq Viewer | Link |
| CLIP-seq Support 2 for dataset GSM545214 | |
|---|---|
| Method / RBP | PAR-CLIP / AGO3 |
| Cell line / Condition | HEK293 / Control |
| Location of target site | ENST00000489308.2 | 3UTR | CAUUUUUCGGUCAUUUGAUUUUGCAUUUUGCACUUCCUCCC |
| Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
| Article / Accession Series | PMID: 20371350 / GSE21578 |
| CLIP-seq Viewer | Link |
| CLIP-seq Support 3 for dataset GSM545216 | |
|---|---|
| Method / RBP | PAR-CLIP / AGO2 |
| Cell line / Condition | HEK293 / miR-124 transfection |
| Location of target site | ENST00000489308.2 | 3UTR | UUCAGCAUUUUUCGGUCAUUUGAUUUUGCAUUUUGCACUUCCUCCCAG |
| Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
| Article / Accession Series | PMID: 20371350 / GSE21578 |
| CLIP-seq Viewer | Link |
| CLIP-seq Support 4 for dataset GSM714645 | |
|---|---|
| Method / RBP | PAR-CLIP / AGO2 |
| Cell line / Condition | HEK293 / completeT1, repB |
| Location of target site | ENST00000489308.2 | 3UTR | AUUUUGCAUUUUGCACUUCCUCCCAG |
| Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
| Article / Accession Series | PMID: 21572407 / GSE28865 |
| CLIP-seq Viewer | Link |
| CLIP-seq Support 5 for dataset GSM1462572 | |
|---|---|
| Method / RBP | PAR-CLIP / AGO2 |
| Cell line / Condition | C8166 / C8166 NL4-3 |
| Location of target site | ENST00000489308.2 | 3UTR | UGCAUUUUGCACUUCCUCCCAG |
| Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
| Article / Accession Series | PMID: 23592263 / GSE59944 |
| CLIP-seq Viewer | Link |
| MiRNA-Target Expression Profile | |||||||
|---|---|---|---|---|---|---|---|
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| MiRNA-Target Expression Profile (TCGA) | |||||||
|---|---|---|---|---|---|---|---|
|
249 hsa-miR-548x-5p Target Genes:
Functional analysis:
ID |
Target | Description | Validation methods |
 |
 |
|||||||
| Strong evidence | Less strong evidence | |||||||||||
 |
 |
 |
 |
 |
 |
 |
 |
|||||
| MIRT057505 | CEP55 | centrosomal protein 55 |  |
|
2 | 4 | ||||||
| MIRT060830 | CEP350 | centrosomal protein 350 | |
|
2 | 4 | ||||||
| MIRT062721 | MLEC | malectin | |
|
2 | 4 | ||||||
| MIRT064767 | CCND2 | cyclin D2 | |
|
2 | 8 | ||||||
| MIRT075338 | SF3B3 | splicing factor 3b subunit 3 | |
|
2 | 2 | ||||||
| MIRT080209 | PRKACB | protein kinase cAMP-activated catalytic subunit beta | |
|
2 | 2 | ||||||
| MIRT080238 | SMAD4 | SMAD family member 4 | |
|
2 | 6 | ||||||
| MIRT087397 | AGFG1 | ArfGAP with FG repeats 1 | |
|
2 | 4 | ||||||
| MIRT088230 | GRAMD4 | GRAM domain containing 4 | |
|
2 | 2 | ||||||
| MIRT089495 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | |
|
2 | 6 | ||||||
| MIRT091224 | USP13 | ubiquitin specific peptidase 13 | |
|
2 | 2 | ||||||
| MIRT092960 | CYP2U1 | cytochrome P450 family 2 subfamily U member 1 | |
|
2 | 4 | ||||||
| MIRT094093 | PAICS | phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase | |
|
2 | 4 | ||||||
| MIRT097470 | PAPD4 | poly(A) RNA polymerase D4, non-canonical | |
|
2 | 2 | ||||||
| MIRT102253 | HBP1 | HMG-box transcription factor 1 | |
|
2 | 4 | ||||||
| MIRT105441 | ATP6V1B2 | ATPase H+ transporting V1 subunit B2 | |
|
2 | 10 | ||||||
| MIRT107289 | FAM73B | mitoguardin 2 | |
|
2 | 2 | ||||||
| MIRT113586 | ZDHHC18 | zinc finger DHHC-type containing 18 | |
|
2 | 2 | ||||||
| MIRT113887 | KPNA6 | karyopherin subunit alpha 6 | |
|
2 | 6 | ||||||
| MIRT126459 | ARL5B | ADP ribosylation factor like GTPase 5B | |
|
2 | 2 | ||||||
| MIRT135026 | ADSS | adenylosuccinate synthase | |
|
2 | 6 | ||||||
| MIRT139893 | BTF3L4 | basic transcription factor 3 like 4 | |
|
2 | 6 | ||||||
| MIRT149712 | LDLR | low density lipoprotein receptor | |
|
2 | 2 | ||||||
| MIRT163234 | EDEM1 | ER degradation enhancing alpha-mannosidase like protein 1 | |
|
2 | 2 | ||||||
| MIRT165202 | GRAMD3 | GRAM domain containing 2B | |
|
2 | 2 | ||||||
| MIRT172173 | FZD6 | frizzled class receptor 6 | |
|
2 | 8 | ||||||
| MIRT177397 | ZMYND11 | zinc finger MYND-type containing 11 | |
|
2 | 2 | ||||||
| MIRT179430 | TBRG1 | transforming growth factor beta regulator 1 | |
|
2 | 6 | ||||||
| MIRT195619 | FAM195A | MAPK regulated corepressor interacting protein 2 | |
|
2 | 6 | ||||||
| MIRT208729 | MED12L | mediator complex subunit 12 like | |
|
2 | 6 | ||||||
| MIRT211511 | ELMOD2 | ELMO domain containing 2 | |
|
2 | 2 | ||||||
| MIRT213435 | MOB1B | MOB kinase activator 1B | |
|
2 | 6 | ||||||
| MIRT240123 | NDRG1 | N-myc downstream regulated 1 | |
|
2 | 2 | ||||||
| MIRT243103 | LCLAT1 | lysocardiolipin acyltransferase 1 | |
|
2 | 4 | ||||||
| MIRT247389 | HCFC2 | host cell factor C2 | |
|
2 | 4 | ||||||
| MIRT248058 | ZBTB18 | zinc finger and BTB domain containing 18 | |
|
2 | 2 | ||||||
| MIRT249459 | ZNF691 | zinc finger protein 691 | |
|
2 | 4 | ||||||
| MIRT253422 | EVI5L | ecotropic viral integration site 5 like | |
|
2 | 2 | ||||||
| MIRT254149 | ETS2 | ETS proto-oncogene 2, transcription factor | |
|
2 | 2 | ||||||
| MIRT258908 | LAPTM4B | lysosomal protein transmembrane 4 beta | |
|
2 | 4 | ||||||
| MIRT259394 | SLC6A8 | solute carrier family 6 member 8 | |
|
2 | 4 | ||||||
| MIRT266973 | LRRC55 | leucine rich repeat containing 55 | |
|
2 | 4 | ||||||
| MIRT279002 | GMFB | glia maturation factor beta | |
|
2 | 10 | ||||||
| MIRT288803 | KCNJ2 | potassium voltage-gated channel subfamily J member 2 | |
|
2 | 2 | ||||||
| MIRT325680 | ZNF367 | zinc finger protein 367 | |
|
2 | 2 | ||||||
| MIRT330544 | HNRNPF | heterogeneous nuclear ribonucleoprotein F | |
|
2 | 4 | ||||||
| MIRT334273 | RCC2 | regulator of chromosome condensation 2 | |
|
2 | 2 | ||||||
| MIRT350226 | PRNP | prion protein | |
|
2 | 2 | ||||||
| MIRT400513 | SKIL | SKI like proto-oncogene | |
|
2 | 10 | ||||||
| MIRT405640 | WBP4 | WW domain binding protein 4 | |
|
2 | 4 | ||||||
| MIRT408652 | QKI | QKI, KH domain containing RNA binding | |
|
2 | 2 | ||||||
| MIRT444160 | ZNF701 | zinc finger protein 701 | |
|
2 | 2 | ||||||
| MIRT444508 | ZNF525 | zinc finger protein 525 | |
|
2 | 2 | ||||||
| MIRT445208 | CRYBG3 | crystallin beta-gamma domain containing 3 | |
|
2 | 2 | ||||||
| MIRT446843 | FOXP1 | forkhead box P1 | |
|
2 | 2 | ||||||
| MIRT449025 | ADRB1 | adrenoceptor beta 1 | |
|
2 | 2 | ||||||
| MIRT450745 | POLI | DNA polymerase iota | |
|
2 | 4 | ||||||
| MIRT450792 | OTUD7A | OTU deubiquitinase 7A | |
|
2 | 2 | ||||||
| MIRT454915 | ANKEF1 | ankyrin repeat and EF-hand domain containing 1 | |
|
2 | 12 | ||||||
| MIRT455265 | DDX39B | DExD-box helicase 39B | |
|
2 | 10 | ||||||
| MIRT455714 | EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | |
|
2 | 2 | ||||||
| MIRT456097 | MB21D1 | Mab-21 domain containing 1 | |
|
2 | 6 | ||||||
| MIRT463634 | YY1 | YY1 transcription factor | |
|
2 | 8 | ||||||
| MIRT463890 | WNT7B | Wnt family member 7B | |
|
2 | 2 | ||||||
| MIRT466261 | TMBIM6 | transmembrane BAX inhibitor motif containing 6 | |
|
2 | 4 | ||||||
| MIRT466819 | STX6 | syntaxin 6 | |
|
2 | 6 | ||||||
| MIRT466878 | STX16 | syntaxin 16 | |
|
2 | 2 | ||||||
| MIRT467523 | SMG1 | SMG1, nonsense mediated mRNA decay associated PI3K related kinase | |
|
2 | 6 | ||||||
| MIRT468198 | SGK1 | serum/glucocorticoid regulated kinase 1 | |
|
2 | 2 | ||||||
| MIRT468632 | SELT | selenoprotein T | |
|
2 | 2 | ||||||
| MIRT470366 | PPP2R5E | protein phosphatase 2 regulatory subunit B'epsilon | |
|
2 | 2 | ||||||
| MIRT470997 | PITPNA | phosphatidylinositol transfer protein alpha | |
|
2 | 2 | ||||||
| MIRT471558 | PATL1 | PAT1 homolog 1, processing body mRNA decay factor | |
|
2 | 6 | ||||||
| MIRT472276 | NFIB | nuclear factor I B | |
|
2 | 4 | ||||||
| MIRT472757 | MTMR6 | myotubularin related protein 6 | |
|
2 | 8 | ||||||
| MIRT474718 | KIF13A | kinesin family member 13A | |
|
2 | 6 | ||||||
| MIRT475868 | H3F3C | H3 histone family member 3C | |
|
2 | 10 | ||||||
| MIRT475902 | H3F3B | H3 histone family member 3B | |
|
2 | 8 | ||||||
| MIRT477349 | EOGT | EGF domain specific O-linked N-acetylglucosamine transferase | |
|
2 | 4 | ||||||
| MIRT477485 | ELL2 | elongation factor for RNA polymerase II 2 | |
|
2 | 2 | ||||||
| MIRT478095 | DLG5 | discs large MAGUK scaffold protein 5 | |
|
2 | 6 | ||||||
| MIRT479804 | CCNA2 | cyclin A2 | |
|
2 | 6 | ||||||
| MIRT480812 | BLCAP | bladder cancer associated protein | |
|
2 | 10 | ||||||
| MIRT481946 | ANKRD11 | ankyrin repeat domain 11 | |
|
2 | 2 | ||||||
| MIRT483059 | EXT2 | exostosin glycosyltransferase 2 | |
|
2 | 6 | ||||||
| MIRT484142 | LRRC45 | leucine rich repeat containing 45 | |
|
2 | 4 | ||||||
| MIRT484903 | ZFYVE26 | zinc finger FYVE-type containing 26 | |
|
2 | 4 | ||||||
| MIRT485079 | SOX4 | SRY-box 4 | |
|
2 | 10 | ||||||
| MIRT485638 | DICER1 | dicer 1, ribonuclease III | |
|
2 | 4 | ||||||
| MIRT485797 | ARPP19 | cAMP regulated phosphoprotein 19 | |
|
2 | 2 | ||||||
| MIRT486270 | SEC23A | Sec23 homolog A, coat complex II component | |
|
2 | 2 | ||||||
| MIRT486739 | CNOT4 | CCR4-NOT transcription complex subunit 4 | |
|
2 | 6 | ||||||
| MIRT487166 | LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | |
|
2 | 2 | ||||||
| MIRT491641 | PDRG1 | p53 and DNA damage regulated 1 | |
|
2 | 10 | ||||||
| MIRT491933 | WDR45B | WD repeat domain 45B | |
|
2 | 8 | ||||||
| MIRT492231 | SLC48A1 | solute carrier family 48 member 1 | |
|
2 | 2 | ||||||
| MIRT493088 | MMGT1 | membrane magnesium transporter 1 | |
|
2 | 12 | ||||||
| MIRT494478 | BRWD3 | bromodomain and WD repeat domain containing 3 | |
|
2 | 2 | ||||||
| MIRT494985 | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | |
|
2 | 2 | ||||||
| MIRT495670 | ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | |
|
2 | 2 | ||||||
| MIRT498466 | PTBP2 | polypyrimidine tract binding protein 2 | |
|
2 | 10 | ||||||
| MIRT499267 | NBPF11 | NBPF member 11 | |
|
2 | 2 | ||||||
| MIRT499853 | SVOP | SV2 related protein | |
|
2 | 12 | ||||||
| MIRT500306 | ZNF622 | zinc finger protein 622 | |
|
2 | 8 | ||||||
| MIRT500639 | TUBB2A | tubulin beta 2A class IIa | |
|
2 | 8 | ||||||
| MIRT501221 | SEMA4C | semaphorin 4C | |
|
2 | 6 | ||||||
| MIRT501525 | PPP1R15B | protein phosphatase 1 regulatory subunit 15B | |
|
2 | 8 | ||||||
| MIRT501568 | PLEKHF2 | pleckstrin homology and FYVE domain containing 2 | |
|
2 | 4 | ||||||
| MIRT502429 | G3BP2 | G3BP stress granule assembly factor 2 | |
|
2 | 10 | ||||||
| MIRT502966 | CCNL1 | cyclin L1 | |
|
2 | 8 | ||||||
| MIRT503469 | ZNF154 | zinc finger protein 154 | |
|
2 | 6 | ||||||
| MIRT504571 | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit | |
|
2 | 4 | ||||||
| MIRT504955 | ZNRF2 | zinc and ring finger 2 | |
|
2 | 6 | ||||||
| MIRT505205 | UBN2 | ubinuclein 2 | |
|
2 | 8 | ||||||
| MIRT505237 | UBE2D3 | ubiquitin conjugating enzyme E2 D3 | |
|
2 | 2 | ||||||
| MIRT507569 | DEK | DEK proto-oncogene | |
|
2 | 2 | ||||||
| MIRT509411 | MCM7 | minichromosome maintenance complex component 7 | |
|
2 | 6 | ||||||
| MIRT510714 | SPG20 | spartin | |
|
2 | 6 | ||||||
| MIRT510858 | RAN | RAN, member RAS oncogene family | |
|
2 | 8 | ||||||
| MIRT510913 | PSMA2 | proteasome subunit alpha 2 | |
|
2 | 4 | ||||||
| MIRT510943 | PPTC7 | PTC7 protein phosphatase homolog | |
|
2 | 8 | ||||||
| MIRT511071 | NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | |
|
2 | 4 | ||||||
| MIRT511212 | LNPEP | leucyl and cystinyl aminopeptidase | |
|
2 | 4 | ||||||
| MIRT511958 | ELOVL5 | ELOVL fatty acid elongase 5 | |
|
2 | 6 | ||||||
| MIRT512122 | CREBL2 | cAMP responsive element binding protein like 2 | |
|
2 | 8 | ||||||
| MIRT513685 | RNF111 | ring finger protein 111 | |
|
2 | 2 | ||||||
| MIRT513895 | GRB10 | growth factor receptor bound protein 10 | |
|
2 | 6 | ||||||
| MIRT516304 | F8A2 | coagulation factor VIII associated 2 | |
|
2 | 2 | ||||||
| MIRT516330 | F8A3 | coagulation factor VIII associated 3 | |
|
2 | 2 | ||||||
| MIRT517520 | ITM2C | integral membrane protein 2C | |
|
2 | 6 | ||||||
| MIRT517929 | IMPA1 | inositol monophosphatase 1 | |
|
2 | 2 | ||||||
| MIRT521367 | RNF11 | ring finger protein 11 | |
|
2 | 6 | ||||||
| MIRT525191 | ZNF93 | zinc finger protein 93 | |
|
2 | 2 | ||||||
| MIRT527215 | CCNL2 | cyclin L2 | |
|
2 | 2 | ||||||
| MIRT527834 | NUPL1 | nucleoporin 58 | |
|
2 | 2 | ||||||
| MIRT529432 | MALT1 | MALT1 paracaspase | |
|
2 | 2 | ||||||
| MIRT530165 | C11orf44 | chromosome 11 open reading frame 44 | |
|
2 | 4 | ||||||
| MIRT530514 | C4orf32 | family with sequence similarity 241 member A | |
|
2 | 4 | ||||||
| MIRT532371 | LINC00598 | long intergenic non-protein coding RNA 598 | |
|
2 | 2 | ||||||
| MIRT533854 | TEAD1 | TEA domain transcription factor 1 | |
|
2 | 2 | ||||||
| MIRT534749 | RAVER2 | ribonucleoprotein, PTB binding 2 | |
|
2 | 4 | ||||||
| MIRT534794 | RAB8B | RAB8B, member RAS oncogene family | |
|
2 | 2 | ||||||
| MIRT538601 | CDK19 | cyclin dependent kinase 19 | |
|
2 | 2 | ||||||
| MIRT539246 | ANKRD50 | ankyrin repeat domain 50 | |
|
2 | 2 | ||||||
| MIRT539466 | ADARB2 | adenosine deaminase, RNA specific B2 (inactive) | |
|
2 | 2 | ||||||
| MIRT543099 | TNFRSF11A | TNF receptor superfamily member 11a | |
|
2 | 2 | ||||||
| MIRT543896 | ESYT1 | extended synaptotagmin 1 | |
|
2 | 2 | ||||||
| MIRT544979 | MFF | mitochondrial fission factor | |
|
2 | 4 | ||||||
| MIRT545793 | ZNF772 | zinc finger protein 772 | |
|
2 | 4 | ||||||
| MIRT546008 | WDR26 | WD repeat domain 26 | |
|
2 | 4 | ||||||
| MIRT546377 | STOX2 | storkhead box 2 | |
|
2 | 4 | ||||||
| MIRT546680 | RORA | RAR related orphan receptor A | |
|
2 | 4 | ||||||
| MIRT546946 | SFTPA1 | surfactant protein A1 | |
|
2 | 2 | ||||||
| MIRT547033 | POGZ | pogo transposable element derived with ZNF domain | |
|
2 | 2 | ||||||
| MIRT547396 | MKX | mohawk homeobox | |
|
2 | 2 | ||||||
| MIRT547469 | MBNL3 | muscleblind like splicing regulator 3 | |
|
2 | 4 | ||||||
| MIRT547500 | MBNL1 | muscleblind like splicing regulator 1 | |
|
2 | 4 | ||||||
| MIRT548076 | GIGYF1 | GRB10 interacting GYF protein 1 | |
|
2 | 2 | ||||||
| MIRT548499 | E2F8 | E2F transcription factor 8 | |
|
2 | 2 | ||||||
| MIRT548882 | CHEK2 | checkpoint kinase 2 | |
|
2 | 4 | ||||||
| MIRT549062 | CALM1 | calmodulin 1 | |
|
2 | 2 | ||||||
| MIRT549165 | BMP3 | bone morphogenetic protein 3 | |
|
2 | 2 | ||||||
| MIRT549309 | ARHGAP12 | Rho GTPase activating protein 12 | |
|
2 | 4 | ||||||
| MIRT549344 | ARC | activity regulated cytoskeleton associated protein | |
|
2 | 2 | ||||||
| MIRT549474 | ACBD5 | acyl-CoA binding domain containing 5 | |
|
2 | 2 | ||||||
| MIRT549677 | ZNF598 | zinc finger protein 598 | |
|
2 | 2 | ||||||
| MIRT550208 | MAVS | mitochondrial antiviral signaling protein | |
|
2 | 4 | ||||||
| MIRT550355 | INCENP | inner centromere protein | |
|
2 | 4 | ||||||
| MIRT550530 | MYZAP | myocardial zonula adherens protein | |
|
2 | 2 | ||||||
| MIRT551155 | ZNF678 | zinc finger protein 678 | |
|
2 | 2 | ||||||
| MIRT552310 | ZXDA | zinc finger, X-linked, duplicated A | |
|
2 | 4 | ||||||
| MIRT552879 | WASL | Wiskott-Aldrich syndrome like | |
|
2 | 4 | ||||||
| MIRT553382 | TRIM33 | tripartite motif containing 33 | |
|
2 | 2 | ||||||
| MIRT554452 | SAMD8 | sterile alpha motif domain containing 8 | |
|
2 | 2 | ||||||
| MIRT554867 | RCAN2 | regulator of calcineurin 2 | |
|
2 | 2 | ||||||
| MIRT556021 | MYBL1 | MYB proto-oncogene like 1 | |
|
2 | 2 | ||||||
| MIRT556174 | MCC | mutated in colorectal cancers | |
|
2 | 2 | ||||||
| MIRT556237 | MARCKS | myristoylated alanine rich protein kinase C substrate | |
|
2 | 2 | ||||||
| MIRT556877 | ITGA2 | integrin subunit alpha 2 | |
|
2 | 2 | ||||||
| MIRT557574 | GNPTAB | N-acetylglucosamine-1-phosphate transferase alpha and beta subunits | |
|
2 | 2 | ||||||
| MIRT557689 | GATA6 | GATA binding protein 6 | |
|
2 | 2 | ||||||
| MIRT557905 | FBXO8 | F-box protein 8 | |
|
2 | 2 | ||||||
| MIRT558131 | ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | |
|
2 | 2 | ||||||
| MIRT558480 | DBN1 | drebrin 1 | |
|
2 | 2 | ||||||
| MIRT558743 | CHIC1 | cysteine rich hydrophobic domain 1 | |
|
2 | 2 | ||||||
| MIRT558759 | CFL2 | cofilin 2 | |
|
2 | 2 | ||||||
| MIRT559121 | C11orf57 | chromosome 11 open reading frame 57 | |
|
2 | 2 | ||||||
| MIRT559405 | GDNF | glial cell derived neurotrophic factor | |
|
2 | 4 | ||||||
| MIRT559475 | ARL8A | ADP ribosylation factor like GTPase 8A | |
|
2 | 2 | ||||||
| MIRT559676 | AGO3 | argonaute 3, RISC catalytic component | |
|
2 | 2 | ||||||
| MIRT560048 | ZNF680 | zinc finger protein 680 | |
|
2 | 2 | ||||||
| MIRT560644 | ZNF107 | zinc finger protein 107 | |
|
2 | 2 | ||||||
| MIRT562580 | CBX3 | chromobox 3 | |
|
2 | 2 | ||||||
| MIRT564187 | CLVS2 | clavesin 2 | |
|
2 | 2 | ||||||
| MIRT564529 | SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide | |
|
2 | 2 | ||||||
| MIRT564539 | CCDC80 | coiled-coil domain containing 80 | |
|
2 | 2 | ||||||
| MIRT565288 | TMPPE | transmembrane protein with metallophosphoesterase domain | |
|
2 | 2 | ||||||
| MIRT565314 | TMEM41A | transmembrane protein 41A | |
|
2 | 2 | ||||||
| MIRT565949 | RRAGD | Ras related GTP binding D | |
|
2 | 2 | ||||||
| MIRT566632 | NFYA | nuclear transcription factor Y subunit alpha | |
|
2 | 4 | ||||||
| MIRT566817 | MAPK8 | mitogen-activated protein kinase 8 | |
|
2 | 2 | ||||||
| MIRT567528 | FGFR1OP | FGFR1 oncogene partner | |
|
2 | 2 | ||||||
| MIRT568630 | ACVR2A | activin A receptor type 2A | |
|
2 | 2 | ||||||
| MIRT572140 | DESI1 | desumoylating isopeptidase 1 | |
|
2 | 2 | ||||||
| MIRT616028 | TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | |
|
2 | 4 | ||||||
| MIRT620047 | ODF4 | outer dense fiber of sperm tails 4 | |
|
2 | 2 | ||||||
| MIRT620530 | AVPR1A | arginine vasopressin receptor 1A | |
|
2 | 2 | ||||||
| MIRT621877 | TAOK3 | TAO kinase 3 | |
|
2 | 2 | ||||||
| MIRT623241 | MLLT6 | MLLT6, PHD finger containing | |
|
2 | 2 | ||||||
| MIRT623993 | FAM104A | family with sequence similarity 104 member A | |
|
2 | 2 | ||||||
| MIRT624300 | COL12A1 | collagen type XII alpha 1 chain | |
|
2 | 2 | ||||||
| MIRT626282 | PEX26 | peroxisomal biogenesis factor 26 | |
|
2 | 2 | ||||||
| MIRT627770 | RAB30 | RAB30, member RAS oncogene family | |
|
2 | 2 | ||||||
| MIRT641138 | ZBTB33 | zinc finger and BTB domain containing 33 | |
|
2 | 2 | ||||||
| MIRT644586 | SPOP | speckle type BTB/POZ protein | |
|
2 | 2 | ||||||
| MIRT644819 | DNAJC21 | DnaJ heat shock protein family (Hsp40) member C21 | |
|
2 | 2 | ||||||
| MIRT645970 | NHLRC2 | NHL repeat containing 2 | |
|
2 | 2 | ||||||
| MIRT646170 | PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | |
|
2 | 2 | ||||||
| MIRT646495 | ZNF429 | zinc finger protein 429 | |
|
2 | 2 | ||||||
| MIRT647833 | RAB23 | RAB23, member RAS oncogene family | |
|
2 | 2 | ||||||
| MIRT648462 | CCDC127 | coiled-coil domain containing 127 | |
|
2 | 2 | ||||||
| MIRT657280 | HRK | harakiri, BCL2 interacting protein | |
|
2 | 2 | ||||||
| MIRT658643 | ENAH | ENAH, actin regulator | |
|
2 | 2 | ||||||
| MIRT658676 | EMP2 | epithelial membrane protein 2 | |
|
2 | 2 | ||||||
| MIRT665228 | ZZZ3 | zinc finger ZZ-type containing 3 | |
|
2 | 2 | ||||||
| MIRT669276 | C19orf44 | chromosome 19 open reading frame 44 | |
|
2 | 2 | ||||||
| MIRT676047 | AUTS8 | Autism, susceptibility to, 8 | |
|
2 | 2 | ||||||
| MIRT681483 | DIP2A | disco interacting protein 2 homolog A | |
|
2 | 2 | ||||||
| MIRT681554 | UBXN2A | UBX domain protein 2A | |
|
2 | 2 | ||||||
| MIRT683142 | MTHFD1 | methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 | |
|
2 | 2 | ||||||
| MIRT688534 | DCAF7 | DDB1 and CUL4 associated factor 7 | |
|
2 | 2 | ||||||
| MIRT689428 | CYB561 | cytochrome b561 | |
|
2 | 2 | ||||||
| MIRT689534 | KIAA0513 | KIAA0513 | |
|
2 | 2 | ||||||
| MIRT689894 | SOD2 | superoxide dismutase 2 | |
|
2 | 2 | ||||||
| MIRT695989 | SNX19 | sorting nexin 19 | |
|
2 | 2 | ||||||
| MIRT697780 | UBXN7 | UBX domain protein 7 | |
|
2 | 2 | ||||||
| MIRT702914 | CRAMP1L | cramped chromatin regulator homolog 1 | |
|
2 | 2 | ||||||
| MIRT703144 | GPR137C | G protein-coupled receptor 137C | |
|
2 | 2 | ||||||
| MIRT703524 | FKBP15 | FK506 binding protein 15 | |
|
2 | 2 | ||||||
| MIRT704536 | CNEP1R1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1 | |
|
2 | 2 | ||||||
| MIRT704997 | CAMSAP1 | calmodulin regulated spectrin associated protein 1 | |
|
2 | 2 | ||||||
| MIRT705721 | AMMECR1L | AMMECR1 like | |
|
2 | 2 | ||||||
| MIRT707120 | NWD1 | NACHT and WD repeat domain containing 1 | |
|
2 | 2 | ||||||
| MIRT707451 | PPFIBP1 | PPFIA binding protein 1 | |
|
2 | 2 | ||||||
| MIRT707775 | WNK3 | WNK lysine deficient protein kinase 3 | |
|
2 | 2 | ||||||
| MIRT707888 | SLC30A7 | solute carrier family 30 member 7 | |
|
2 | 2 | ||||||
| MIRT720531 | CHERP | calcium homeostasis endoplasmic reticulum protein | |
|
2 | 2 | ||||||
| MIRT723859 | CD209 | CD209 molecule | |
|
2 | 2 | ||||||
| MIRT725349 | MUC21 | mucin 21, cell surface associated | |
|
2 | 2 | ||||||