miRTarBase - #MIRT146657


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pre-miRNA Information
pre-miRNA hsa-mir-3179-1   
Genomic Coordinates chr16: 14901508 - 14901591
Description Homo sapiens miR-3179-1 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-2   
Genomic Coordinates chr16: 16300159 - 16300242
Description Homo sapiens miR-3179-2 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-3   
Genomic Coordinates chr16: 18411894 - 18411977
Description Homo sapiens miR-3179-3 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-3179-4   
Genomic Coordinates chr16: 18494493 - 18494576
Description Homo sapiens miR-3179-4 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-3179
Sequence 52| AGAAGGGGUGAAAUUUAAACGU |73
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1351100204 1 dbSNP
rs1398613616 4 dbSNP
rs1340262765 20 dbSNP
rs1229893475 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol MINK1   
Synonyms B55, MAP4K6, MINK, YSK2, ZC3
Description misshapen like kinase 1
Transcript NM_001024937   
Other Transcripts NM_015716 , NM_153827 , NM_170663   
Expression
Putative miRNA Targets on MINK1
3'UTR of MINK1
(miRNA target sites are highlighted)		 
>MINK1|NM_001024937|3'UTR
   1 CGGGGCCCTGGGCTGGGGCTGTCCCACACTGGACCCAGCTCTCCCCCTGCAGCCAGGCTTCCCGGGCCGCCCCTCTTTCC
  81 CCTCCCTGGGCTTTTGCTTTTACTGGTTTGATTTCACTGGAGCCTGCTGGGAACGTGACCTCTGACCCCTGATGCTTTCG
 161 TGATCACGTGACCATCCTCTTCCCCAACATGTCCTCTTCCCAAAACTGTGCCTGTCCCCAGCTTCTGGGGAGGGACACAG
 241 CTTCCCCTTCCCAGGAATTGAGTGGGCCTAGCCCCTCCCCCCTTTTCTCCATTTGAGAGGAGAGTGCTTGGGGCTTGAAC
 321 CCCTTACCCCACTGCTGCTGACTGGGCAGGGCCCTGGACCCCTTTATTTGCACGTCAGGGGAGCCGGCTCCCCCCTTGAA
 401 TGTACCAGACCCTGGGGGGGGTCACTGGGCCCTAGATTTTTGGGGGGTCACCAGCCACTCCAGGGGCAGGGACCATTTCT
 481 TCATTTTCTGAAAGCACTTTAATGATTCCCCTTCCCCCAAACTCCAGGGAATGGAGGGGGGACCCCGCCAGCCAAAACAT
 561 TCCCCCCATTCCCGACCCCCCTCTCCTCTTCTAGCCCATGCCCTTCCCCGGTGGAGGGAGGGAGCAGGGAGCCCTCACTC
 641 TCCACGCCCCTTGCTTGCATCTGTATATAGTGTGAGCAGCAAGTAACCCTTCTCCCTCCCCCCCCACCCCTCCTCAATGT
 721 AGTGGCCTTGGATATCCTGTTTGTTAATAAAGACAATTCAACCAGCTCCCACCAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugcAAAUU--UAAAGUGGGGAAGa 5'
             |||||  |||   ||||||| 
Target 5' cacTTTAATGATT---CCCCTTCc 3'
 495 - 515 158.00 -12.50
2 
miRNA  3' ugcaaauUUAAAGUGGGGAAGa 5'
                 |: ||  ||||||| 
Target 5' gggacacAGCTT--CCCCTTCc 3'
 232 - 251 143.00 -11.60
3 
miRNA  3' ugCAAAUUU--AAAGUGGGGAAga 5'
            | ||:::  ||  |||||||  
Target 5' gtGCTTGGGGCTTGAACCCCTTac 3'
 304 - 327 134.00 -12.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
323942 520 ClinVar
323943 544 ClinVar
323944 547 ClinVar
323945 548 ClinVar
323946 574 ClinVar
323947 575 ClinVar
323948 582 ClinVar
323949 592 ClinVar
890890 595 ClinVar
323950 598 ClinVar
323951 613 ClinVar
323952 614 ClinVar
323953 644 ClinVar
323954 645 ClinVar
323955 670 ClinVar
323956 692 ClinVar
892125 702 ClinVar
323957 705 ClinVar
323958 705 ClinVar
323959 707 ClinVar
COSN30520026 11 COSMIC
COSN30498771 14 COSMIC
COSN31480032 16 COSMIC
COSN8243256 21 COSMIC
COSN30452583 26 COSMIC
COSN30461873 55 COSMIC
COSN30491284 72 COSMIC
COSN30512501 151 COSMIC
COSN31596417 230 COSMIC
COSN18000122 414 COSMIC
COSN28723960 442 COSMIC
COSN28759957 447 COSMIC
COSN32065392 519 COSMIC
COSN22762751 525 COSMIC
COSN8603337 546 COSMIC
COSN6657741 582 COSMIC
COSN28652785 613 COSMIC
COSN8603338 648 COSMIC
COSN27598496 696 COSMIC
rs7774 582 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs144736076 2 dbSNP
rs199925209 3 dbSNP
rs755856876 4 dbSNP
rs1286151309 5 dbSNP
rs777364049 6 dbSNP
rs748815511 7 dbSNP
rs1005413586 8 dbSNP
rs1283695441 10 dbSNP
rs780484680 10 dbSNP
rs770632922 11 dbSNP
rs2586530 14 dbSNP
rs1190203686 15 dbSNP
rs774707848 16 dbSNP
rs1266673430 18 dbSNP
rs746436882 19 dbSNP
rs371078087 24 dbSNP
rs775944221 25 dbSNP
rs760827534 27 dbSNP
rs536758486 28 dbSNP
rs1374223617 29 dbSNP
rs960741570 30 dbSNP
rs1417125939 35 dbSNP
rs1313026115 37 dbSNP
rs1334643327 38 dbSNP
rs747408524 42 dbSNP
rs929366130 43 dbSNP
rs779916246 44 dbSNP
rs761863908 46 dbSNP
rs1351164942 47 dbSNP
rs1218481146 50 dbSNP
rs1298017770 54 dbSNP
rs1484958232 61 dbSNP
rs1013561233 62 dbSNP
rs570073299 64 dbSNP
rs970073867 65 dbSNP
rs1190494334 67 dbSNP
rs746819192 69 dbSNP
rs1194284223 70 dbSNP
rs1230165380 70 dbSNP
rs1032963417 71 dbSNP
rs956886179 72 dbSNP
rs748792686 75 dbSNP
rs1172817042 76 dbSNP
rs1451988689 76 dbSNP
rs535510575 77 dbSNP
rs901702640 84 dbSNP
rs997264815 87 dbSNP
rs1373444023 89 dbSNP
rs988680576 92 dbSNP
rs1467505258 97 dbSNP
rs1278149141 101 dbSNP
rs1303420665 102 dbSNP
rs1333195173 103 dbSNP
rs1321765036 106 dbSNP
rs1402914064 114 dbSNP
rs912988639 116 dbSNP
rs145364388 118 dbSNP
rs955829655 120 dbSNP
rs768507520 123 dbSNP
rs921582890 124 dbSNP
rs1167291068 125 dbSNP
rs565928100 128 dbSNP
rs1478194970 130 dbSNP
rs1229462880 131 dbSNP
rs1303099682 133 dbSNP
rs1450747597 134 dbSNP
rs908062308 134 dbSNP
rs535032519 135 dbSNP
rs1220333179 136 dbSNP
rs1257904413 136 dbSNP
rs970100355 136 dbSNP
rs1257103745 137 dbSNP
rs558148712 138 dbSNP
rs926824470 144 dbSNP
rs1333639857 147 dbSNP
rs375938060 147 dbSNP
rs1444600686 148 dbSNP
rs1202880731 149 dbSNP
rs939510054 150 dbSNP
rs992359818 152 dbSNP
rs1465045979 154 dbSNP
rs919420965 155 dbSNP
rs369766748 160 dbSNP
rs780837778 161 dbSNP
rs929429449 165 dbSNP
rs940539640 166 dbSNP
rs577236988 168 dbSNP
rs749573754 169 dbSNP
rs1276916657 170 dbSNP
rs1200186483 171 dbSNP
rs1354903450 174 dbSNP
rs943340570 174 dbSNP
rs1238264205 175 dbSNP
rs1376235652 175 dbSNP
rs896590567 177 dbSNP
rs1448628070 180 dbSNP
rs1360779155 182 dbSNP
rs944871592 183 dbSNP
rs1453094243 184 dbSNP
rs536662233 188 dbSNP
rs565007794 189 dbSNP
rs1160076461 192 dbSNP
rs1013611913 197 dbSNP
rs746525924 207 dbSNP
rs868200779 207 dbSNP
rs1023616084 208 dbSNP
rs182306652 209 dbSNP
rs905191014 210 dbSNP
rs1365850719 213 dbSNP
rs1187865504 215 dbSNP
rs1488786563 216 dbSNP
rs1388901612 220 dbSNP
rs1001557880 234 dbSNP
rs867174292 235 dbSNP
rs1011337256 237 dbSNP
rs573780110 240 dbSNP
rs1021767648 242 dbSNP
rs1230065952 244 dbSNP
rs1377079023 247 dbSNP
rs751232934 251 dbSNP
rs1269459790 254 dbSNP
rs957137018 259 dbSNP
rs1414154474 265 dbSNP
rs988326670 267 dbSNP
rs1299853406 274 dbSNP
rs1417460904 277 dbSNP
rs1019763022 279 dbSNP
rs542704210 281 dbSNP
rs559627643 282 dbSNP
rs1164816092 283 dbSNP
rs1215101467 284 dbSNP
rs1478472604 291 dbSNP
rs1265755221 295 dbSNP
rs1250762860 297 dbSNP
rs1485765234 297 dbSNP
rs752356843 299 dbSNP
rs1224067364 300 dbSNP
rs1247443314 300 dbSNP
rs992394274 304 dbSNP
rs950919899 306 dbSNP
rs552217257 307 dbSNP
rs1318584786 309 dbSNP
rs1280046992 314 dbSNP
rs1249602050 317 dbSNP
rs573070213 318 dbSNP
rs867562048 322 dbSNP
rs943391037 329 dbSNP
rs373161729 331 dbSNP
rs1414271906 332 dbSNP
rs1457839858 333 dbSNP
rs748024967 338 dbSNP
rs1164412878 339 dbSNP
rs1426348430 347 dbSNP
rs1169172745 348 dbSNP
rs1428231792 350 dbSNP
rs1426386486 358 dbSNP
rs1348382650 359 dbSNP
rs921630151 361 dbSNP
rs931676934 367 dbSNP
rs984825795 372 dbSNP
rs1039049187 375 dbSNP
rs771715354 377 dbSNP
rs1459166860 385 dbSNP
rs909152886 386 dbSNP
rs371887618 387 dbSNP
rs1373122160 388 dbSNP
rs1052938036 390 dbSNP
rs891643635 391 dbSNP
rs1036182961 393 dbSNP
rs1290827611 394 dbSNP
rs1220980576 395 dbSNP
rs896304856 396 dbSNP
rs1446795352 398 dbSNP
rs1401864780 403 dbSNP
rs1042818284 414 dbSNP
rs905640348 414 dbSNP
rs949511240 415 dbSNP
rs1001291717 416 dbSNP
rs1287250779 416 dbSNP
rs1394664842 416 dbSNP
rs565049559 417 dbSNP
rs1441556722 418 dbSNP
rs959682703 419 dbSNP
rs1045120672 420 dbSNP
rs1256347533 423 dbSNP
rs1211913446 427 dbSNP
rs1026544778 432 dbSNP
rs1302167498 433 dbSNP
rs1040456760 437 dbSNP
rs985330528 441 dbSNP
rs900569246 442 dbSNP
rs965181031 442 dbSNP
rs974785089 442 dbSNP
rs549911444 445 dbSNP
rs1000874985 447 dbSNP
rs1252468497 448 dbSNP
rs933298085 449 dbSNP
rs996663641 451 dbSNP
rs1159456708 453 dbSNP
rs1421820837 460 dbSNP
rs1162003126 461 dbSNP
rs1181241437 461 dbSNP
rs1424494451 462 dbSNP
rs1256721150 463 dbSNP
rs1183542724 464 dbSNP
rs776944946 468 dbSNP
rs1355473930 472 dbSNP
rs1054172828 475 dbSNP
rs1237659462 476 dbSNP
rs1258612410 476 dbSNP
rs1411773789 480 dbSNP
rs1399638221 498 dbSNP
rs1413534922 501 dbSNP
rs1407275489 506 dbSNP
rs1299231687 509 dbSNP
rs879032301 510 dbSNP
rs1402053597 518 dbSNP
rs1165828142 519 dbSNP
rs186131152 519 dbSNP
rs116802199 520 dbSNP
rs1009807813 521 dbSNP
rs1474208653 522 dbSNP
rs1256515727 527 dbSNP
rs759610943 528 dbSNP
rs1019815736 533 dbSNP
rs947315074 535 dbSNP
rs1043323196 536 dbSNP
rs1259152431 536 dbSNP
rs965531771 538 dbSNP
rs1428233101 539 dbSNP
rs937104820 542 dbSNP
rs9914357 544 dbSNP
rs1334818228 545 dbSNP
rs895503502 546 dbSNP
rs549064723 547 dbSNP
rs369145199 548 dbSNP
rs1281900603 552 dbSNP
rs1387631728 554 dbSNP
rs886724927 556 dbSNP
rs1324025381 559 dbSNP
rs1461012131 563 dbSNP
rs1417031162 564 dbSNP
rs1380782081 569 dbSNP
rs1371182881 573 dbSNP
rs192238331 574 dbSNP
rs886053112 575 dbSNP
rs1211222635 576 dbSNP
rs1467662772 576 dbSNP
rs1311837297 577 dbSNP
rs1337851600 582 dbSNP
rs7774 582 dbSNP
rs1270023451 583 dbSNP
rs1339737560 586 dbSNP
rs1301569196 587 dbSNP
rs1440185387 589 dbSNP
rs1401145465 591 dbSNP
rs375660349 592 dbSNP
rs575836707 595 dbSNP
rs761256289 598 dbSNP
rs1394026113 599 dbSNP
rs974816211 601 dbSNP
rs1478245676 602 dbSNP
rs1396466948 606 dbSNP
rs1191366147 608 dbSNP
rs1485280605 609 dbSNP
rs1030332396 610 dbSNP
rs961959749 611 dbSNP
rs971952942 612 dbSNP
rs8834 613 dbSNP
rs886053113 614 dbSNP
rs1347588797 620 dbSNP
rs913226820 622 dbSNP
rs1233922096 626 dbSNP
rs1419143167 627 dbSNP
rs1448015976 628 dbSNP
rs1044836031 630 dbSNP
rs529707167 634 dbSNP
rs1311602893 635 dbSNP
rs1333856152 637 dbSNP
rs1371585584 638 dbSNP
rs1414755162 641 dbSNP
rs1377060107 643 dbSNP
rs886053114 644 dbSNP
rs113366718 645 dbSNP
rs1053818311 646 dbSNP
rs374217615 647 dbSNP
rs1232745105 648 dbSNP
rs1056906243 649 dbSNP
rs1009860660 651 dbSNP
rs777911516 662 dbSNP
rs1278725289 664 dbSNP
rs570601986 670 dbSNP
rs901387561 674 dbSNP
rs1222104053 675 dbSNP
rs997037287 679 dbSNP
rs929703752 682 dbSNP
rs1028883995 684 dbSNP
rs1448739379 688 dbSNP
rs367938507 689 dbSNP
rs112548629 690 dbSNP
rs368116445 692 dbSNP
rs368356907 692 dbSNP
rs538982347 692 dbSNP
rs886053115 692 dbSNP
rs1476493939 694 dbSNP
rs201114697 694 dbSNP
rs767446594 695 dbSNP
rs1213926261 697 dbSNP
rs1346895897 697 dbSNP
rs1233803103 698 dbSNP
rs536198075 698 dbSNP
rs868716574 698 dbSNP
rs1047192623 699 dbSNP
rs1232383678 700 dbSNP
rs1280730146 701 dbSNP
rs1340915193 701 dbSNP
rs536398300 702 dbSNP
rs1210967622 703 dbSNP
rs1462578523 704 dbSNP
rs553081443 704 dbSNP
rs746315302 704 dbSNP
rs796874093 704 dbSNP
rs1053751 705 dbSNP
rs886053116 705 dbSNP
rs1247535619 706 dbSNP
rs996264425 706 dbSNP
rs1053754 707 dbSNP
rs1467199360 707 dbSNP
rs1030446932 708 dbSNP
rs1190772375 708 dbSNP
rs1212412737 709 dbSNP
rs1391100612 710 dbSNP
rs1454162612 712 dbSNP
rs1171323798 715 dbSNP
rs1427927486 717 dbSNP
rs954828720 718 dbSNP
rs1442377687 719 dbSNP
rs1325806615 726 dbSNP
rs953186895 726 dbSNP
rs1006365717 728 dbSNP
rs1356609513 731 dbSNP
rs1168718169 733 dbSNP
rs1436751057 734 dbSNP
rs1320811949 738 dbSNP
rs1195749165 751 dbSNP
rs1369968007 758 dbSNP
rs1452648665 761 dbSNP
rs1252530514 762 dbSNP
rs1015970448 764 dbSNP
rs1434098016 766 dbSNP
rs968720821 772 dbSNP
rs1253026396 773 dbSNP
rs558674000 774 dbSNP
rs927194203 775 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ugcAAAUU--UAAAGUGGGGAAGa 5'
             |||||  |||   ||||||| 
Target 5' cacUUUAAUGAUU---CCCCUUCc 3'
 		15 - 35
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000347992.7 | 3UTR | UCAUUUUCUGAAAGCACUUUAAUGAUUCCCCUUCCCCCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
Click to see details
133 hsa-miR-3179 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT102087 GIGYF1 GRB10 interacting GYF protein 1 2 4
MIRT110061 OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2 6
MIRT112198 BTG2 BTG anti-proliferation factor 2 2 2
MIRT117668 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT146657 MINK1 misshapen like kinase 1 2 2
MIRT175505 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT180535 TXNIP thioredoxin interacting protein 2 2
MIRT190624 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 2 2
MIRT190650 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT366902 NONO non-POU domain containing octamer binding 2 2
MIRT443554 ZFP3 ZFP3 zinc finger protein 2 2
MIRT445953 MLLT11 MLLT11, transcription factor 7 cofactor 2 2
MIRT446042 HMCN1 hemicentin 1 2 2
MIRT447968 MSH6 mutS homolog 6 2 2
MIRT448634 ONECUT1 one cut homeobox 1 2 2
MIRT449316 MRO maestro 2 2
MIRT451380 C19orf43 telomerase RNA component interacting RNase 2 2
MIRT451547 CIAPIN1 cytokine induced apoptosis inhibitor 1 2 2
MIRT451807 CDCA3 cell division cycle associated 3 2 4
MIRT451916 ILK integrin linked kinase 2 2
MIRT451938 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452189 KIAA1456 KIAA1456 2 2
MIRT452498 HMGXB3 HMG-box containing 3 2 2
MIRT452548 ZNF467 zinc finger protein 467 2 2
MIRT453844 SDK1 sidekick cell adhesion molecule 1 2 2
MIRT454515 ZFYVE27 zinc finger FYVE-type containing 27 2 2
MIRT455363 KDM5C lysine demethylase 5C 2 2
MIRT455455 EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2 2
MIRT455628 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 10
MIRT455639 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 10
MIRT455690 GLO1 glyoxalase I 2 2
MIRT456300 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT456784 MTHFSD methenyltetrahydrofolate synthetase domain containing 2 2
MIRT456819 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT457566 ZNF34 zinc finger protein 34 2 2
MIRT457604 IDS iduronate 2-sulfatase 2 2
MIRT458236 NXPH3 neurexophilin 3 2 2
MIRT458313 TNFAIP8L3 TNF alpha induced protein 8 like 3 2 2
MIRT458350 NOC2L NOC2 like nucleolar associated transcriptional repressor 2 2
MIRT458670 GPR35 G protein-coupled receptor 35 2 2
MIRT459675 VPS37C VPS37C, ESCRT-I subunit 2 2
MIRT461126 RAB36 RAB36, member RAS oncogene family 2 2
MIRT461918 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462301 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT463520 ZBTB7B zinc finger and BTB domain containing 7B 2 2
MIRT464378 URM1 ubiquitin related modifier 1 2 2
MIRT464614 UBE4B ubiquitination factor E4B 2 2
MIRT464711 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT465520 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT465974 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466058 TMEM189 transmembrane protein 189 2 2
MIRT466548 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT466647 TAGLN2 transgelin 2 2 2
MIRT467357 SP2 Sp2 transcription factor 2 2
MIRT468744 SDC2 syndecan 2 2 2
MIRT470244 PRRC2A proline rich coiled-coil 2A 2 2
MIRT471426 PDIA6 protein disulfide isomerase family A member 6 2 2
MIRT471732 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT472190 NHP2L1 small nuclear ribonucleoprotein 13 2 2
MIRT472450 NAV2 neuron navigator 2 2 6
MIRT474563 KLHDC3 kelch domain containing 3 2 2
MIRT474936 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT475165 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT475399 ICMT isoprenylcysteine carboxyl methyltransferase 2 4
MIRT475426 ICK intestinal cell kinase 2 2
MIRT477090 FAM168A family with sequence similarity 168 member A 2 2
MIRT478458 DAB2 DAB2, clathrin adaptor protein 2 2
MIRT478953 COX15 COX15, cytochrome c oxidase assembly homolog 2 2
MIRT480096 CALR calreticulin 2 2
MIRT481924 ANKRD33B ankyrin repeat domain 33B 2 2
MIRT483217 APOA1 apolipoprotein A1 2 6
MIRT483882 TGIF1 TGFB induced factor homeobox 1 2 2
MIRT483923 SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2 2
MIRT483942 LENG8 leukocyte receptor cluster member 8 2 4
MIRT484209 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT484512 SYT7 synaptotagmin 7 2 2
MIRT484709 RNF11 ring finger protein 11 2 2
MIRT485356 MYO1C myosin IC 2 4
MIRT485615 FOSL1 FOS like 1, AP-1 transcription factor subunit 2 4
MIRT486584 ZNF619 zinc finger protein 619 2 2
MIRT487013 C2orf82 chromosome 2 open reading frame 82 2 2
MIRT487621 C20orf96 chromosome 20 open reading frame 96 2 2
MIRT487801 GPR20 G protein-coupled receptor 20 2 4
MIRT488134 GPR107 G protein-coupled receptor 107 2 2
MIRT488773 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT488854 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT489783 GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 2 2
MIRT490102 FN3K fructosamine 3 kinase 2 2
MIRT490389 LHFPL3 LHFPL tetraspan subfamily member 3 2 2
MIRT490434 MYL9 myosin light chain 9 2 2
MIRT490451 GLUD1 glutamate dehydrogenase 1 2 2
MIRT490880 OSBP oxysterol binding protein 2 2
MIRT491037 ALPK3 alpha kinase 3 2 2
MIRT491250 HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 2 2
MIRT491748 SEMA3F semaphorin 3F 2 2
MIRT492235 SLC48A1 solute carrier family 48 member 1 2 2
MIRT492490 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT492505 RANBP10 RAN binding protein 10 2 4
MIRT492773 PDGFB platelet derived growth factor subunit B 2 2
MIRT492922 NFAT5 nuclear factor of activated T-cells 5 2 2
MIRT493459 ITFG3 family with sequence similarity 234 member A 2 2
MIRT493654 HDLBP high density lipoprotein binding protein 2 2
MIRT494011 DUSP9 dual specificity phosphatase 9 2 2
MIRT499412 PLCG2 phospholipase C gamma 2 2 4
MIRT499552 C15orf43 telomere repeat binding bouquet formation protein 2 2 2
MIRT501836 NCOA2 nuclear receptor coactivator 2 2 2
MIRT501950 MAT2A methionine adenosyltransferase 2A 2 10
MIRT504066 KCTD12 potassium channel tetramerization domain containing 12 2 4
MIRT504509 PPP1R9B protein phosphatase 1 regulatory subunit 9B 2 2
MIRT508466 HOXB6 homeobox B6 2 4
MIRT512373 CPM carboxypeptidase M 2 2
MIRT513578 EVX1 even-skipped homeobox 1 2 2
MIRT517763 ZNF366 zinc finger protein 366 2 4
MIRT519773 ZNF354B zinc finger protein 354B 2 8
MIRT523568 GGCX gamma-glutamyl carboxylase 2 4
MIRT532802 CLDN11 claudin 11 2 2
MIRT544299 TSPYL1 TSPY like 1 2 2
MIRT544862 MYH2 myosin heavy chain 2 2 4
MIRT556731 KLHL15 kelch like family member 15 2 4
MIRT564347 AKR1B10 aldo-keto reductase family 1 member B10 2 2
MIRT568924 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT569012 CXorf36 chromosome X open reading frame 36 2 2
MIRT569256 FAM129B family with sequence similarity 129 member B 2 2
MIRT569591 PRELP proline and arginine rich end leucine rich repeat protein 2 2
MIRT569779 SAMD14 sterile alpha motif domain containing 14 2 2
MIRT570034 FAM228A family with sequence similarity 228 member A 2 2
MIRT573803 FRMPD4 FERM and PDZ domain containing 4 2 2
MIRT574190 ZNF264 zinc finger protein 264 2 2
MIRT576153 Hmox1 heme oxygenase 1 2 2
MIRT611311 CA8 carbonic anhydrase 8 2 4
MIRT673429 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT674976 SH3BP2 SH3 domain binding protein 2 2 2
MIRT692712 MEAF6 MYST/Esa1 associated factor 6 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-3179 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-3179 Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-3179 Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-3179 Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-3179 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-3179 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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