miRTarBase - #MIRT146689


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pre-miRNA Information
pre-miRNA hsa-mir-4747   
Genomic Coordinates chr19: 4932687 - 4932740
Description Homo sapiens miR-4747 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4747-5p
Sequence 1| AGGGAAGGAGGCUUGGUCUUAG |22
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs560927363 4 dbSNP
rs1471226927 10 dbSNP
rs763137545 12 dbSNP
rs767337154 15 dbSNP
rs775298039 16 dbSNP
rs760472311 19 dbSNP
rs1207950315 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol MINK1   
Synonyms B55, MAP4K6, MINK, YSK2, ZC3
Description misshapen like kinase 1
Transcript NM_001024937   
Other Transcripts NM_015716 , NM_153827 , NM_170663   
Expression
Putative miRNA Targets on MINK1
3'UTR of MINK1
(miRNA target sites are highlighted)		 
>MINK1|NM_001024937|3'UTR
   1 CGGGGCCCTGGGCTGGGGCTGTCCCACACTGGACCCAGCTCTCCCCCTGCAGCCAGGCTTCCCGGGCCGCCCCTCTTTCC
  81 CCTCCCTGGGCTTTTGCTTTTACTGGTTTGATTTCACTGGAGCCTGCTGGGAACGTGACCTCTGACCCCTGATGCTTTCG
 161 TGATCACGTGACCATCCTCTTCCCCAACATGTCCTCTTCCCAAAACTGTGCCTGTCCCCAGCTTCTGGGGAGGGACACAG
 241 CTTCCCCTTCCCAGGAATTGAGTGGGCCTAGCCCCTCCCCCCTTTTCTCCATTTGAGAGGAGAGTGCTTGGGGCTTGAAC
 321 CCCTTACCCCACTGCTGCTGACTGGGCAGGGCCCTGGACCCCTTTATTTGCACGTCAGGGGAGCCGGCTCCCCCCTTGAA
 401 TGTACCAGACCCTGGGGGGGGTCACTGGGCCCTAGATTTTTGGGGGGTCACCAGCCACTCCAGGGGCAGGGACCATTTCT
 481 TCATTTTCTGAAAGCACTTTAATGATTCCCCTTCCCCCAAACTCCAGGGAATGGAGGGGGGACCCCGCCAGCCAAAACAT
 561 TCCCCCCATTCCCGACCCCCCTCTCCTCTTCTAGCCCATGCCCTTCCCCGGTGGAGGGAGGGAGCAGGGAGCCCTCACTC
 641 TCCACGCCCCTTGCTTGCATCTGTATATAGTGTGAGCAGCAAGTAACCCTTCTCCCTCCCCCCCCACCCCTCCTCAATGT
 721 AGTGGCCTTGGATATCCTGTTTGTTAATAAAGACAATTCAACCAGCTCCCACCAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaUUCUGGUUCGGA--GGAAGGGa 5'
            ::|||  |||:|  ||||||| 
Target 5' gaGGGACACAGCTTCCCCTTCCCa 3'
 230 - 253 162.00 -20.30
2 
miRNA  3' gauUCUGGUUCGGAGGAAGGGa 5'
             || ||| ||  ||||||| 
Target 5' tctAGCCCATGC--CCTTCCCc 3'
 590 - 609 159.00 -17.40
3 
miRNA  3' gauUCUGGUUCGGAGGAAGGGa 5'
             :|:||:  ||||:||||| 
Target 5' cccGGGCCGCCCCTCTTTCCCc 3'
 61 - 82 151.00 -24.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
323942 520 ClinVar
323943 544 ClinVar
323944 547 ClinVar
323945 548 ClinVar
323946 574 ClinVar
323947 575 ClinVar
323948 582 ClinVar
323949 592 ClinVar
890890 595 ClinVar
323950 598 ClinVar
323951 613 ClinVar
323952 614 ClinVar
323953 644 ClinVar
323954 645 ClinVar
323955 670 ClinVar
323956 692 ClinVar
892125 702 ClinVar
323957 705 ClinVar
323958 705 ClinVar
323959 707 ClinVar
COSN30520026 11 COSMIC
COSN30498771 14 COSMIC
COSN31480032 16 COSMIC
COSN8243256 21 COSMIC
COSN30452583 26 COSMIC
COSN30461873 55 COSMIC
COSN30491284 72 COSMIC
COSN30512501 151 COSMIC
COSN31596417 230 COSMIC
COSN18000122 414 COSMIC
COSN28723960 442 COSMIC
COSN28759957 447 COSMIC
COSN32065392 519 COSMIC
COSN22762751 525 COSMIC
COSN8603337 546 COSMIC
COSN6657741 582 COSMIC
COSN28652785 613 COSMIC
COSN8603338 648 COSMIC
COSN27598496 696 COSMIC
rs7774 582 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs144736076 2 dbSNP
rs199925209 3 dbSNP
rs755856876 4 dbSNP
rs1286151309 5 dbSNP
rs777364049 6 dbSNP
rs748815511 7 dbSNP
rs1005413586 8 dbSNP
rs1283695441 10 dbSNP
rs780484680 10 dbSNP
rs770632922 11 dbSNP
rs2586530 14 dbSNP
rs1190203686 15 dbSNP
rs774707848 16 dbSNP
rs1266673430 18 dbSNP
rs746436882 19 dbSNP
rs371078087 24 dbSNP
rs775944221 25 dbSNP
rs760827534 27 dbSNP
rs536758486 28 dbSNP
rs1374223617 29 dbSNP
rs960741570 30 dbSNP
rs1417125939 35 dbSNP
rs1313026115 37 dbSNP
rs1334643327 38 dbSNP
rs747408524 42 dbSNP
rs929366130 43 dbSNP
rs779916246 44 dbSNP
rs761863908 46 dbSNP
rs1351164942 47 dbSNP
rs1218481146 50 dbSNP
rs1298017770 54 dbSNP
rs1484958232 61 dbSNP
rs1013561233 62 dbSNP
rs570073299 64 dbSNP
rs970073867 65 dbSNP
rs1190494334 67 dbSNP
rs746819192 69 dbSNP
rs1194284223 70 dbSNP
rs1230165380 70 dbSNP
rs1032963417 71 dbSNP
rs956886179 72 dbSNP
rs748792686 75 dbSNP
rs1172817042 76 dbSNP
rs1451988689 76 dbSNP
rs535510575 77 dbSNP
rs901702640 84 dbSNP
rs997264815 87 dbSNP
rs1373444023 89 dbSNP
rs988680576 92 dbSNP
rs1467505258 97 dbSNP
rs1278149141 101 dbSNP
rs1303420665 102 dbSNP
rs1333195173 103 dbSNP
rs1321765036 106 dbSNP
rs1402914064 114 dbSNP
rs912988639 116 dbSNP
rs145364388 118 dbSNP
rs955829655 120 dbSNP
rs768507520 123 dbSNP
rs921582890 124 dbSNP
rs1167291068 125 dbSNP
rs565928100 128 dbSNP
rs1478194970 130 dbSNP
rs1229462880 131 dbSNP
rs1303099682 133 dbSNP
rs1450747597 134 dbSNP
rs908062308 134 dbSNP
rs535032519 135 dbSNP
rs1220333179 136 dbSNP
rs1257904413 136 dbSNP
rs970100355 136 dbSNP
rs1257103745 137 dbSNP
rs558148712 138 dbSNP
rs926824470 144 dbSNP
rs1333639857 147 dbSNP
rs375938060 147 dbSNP
rs1444600686 148 dbSNP
rs1202880731 149 dbSNP
rs939510054 150 dbSNP
rs992359818 152 dbSNP
rs1465045979 154 dbSNP
rs919420965 155 dbSNP
rs369766748 160 dbSNP
rs780837778 161 dbSNP
rs929429449 165 dbSNP
rs940539640 166 dbSNP
rs577236988 168 dbSNP
rs749573754 169 dbSNP
rs1276916657 170 dbSNP
rs1200186483 171 dbSNP
rs1354903450 174 dbSNP
rs943340570 174 dbSNP
rs1238264205 175 dbSNP
rs1376235652 175 dbSNP
rs896590567 177 dbSNP
rs1448628070 180 dbSNP
rs1360779155 182 dbSNP
rs944871592 183 dbSNP
rs1453094243 184 dbSNP
rs536662233 188 dbSNP
rs565007794 189 dbSNP
rs1160076461 192 dbSNP
rs1013611913 197 dbSNP
rs746525924 207 dbSNP
rs868200779 207 dbSNP
rs1023616084 208 dbSNP
rs182306652 209 dbSNP
rs905191014 210 dbSNP
rs1365850719 213 dbSNP
rs1187865504 215 dbSNP
rs1488786563 216 dbSNP
rs1388901612 220 dbSNP
rs1001557880 234 dbSNP
rs867174292 235 dbSNP
rs1011337256 237 dbSNP
rs573780110 240 dbSNP
rs1021767648 242 dbSNP
rs1230065952 244 dbSNP
rs1377079023 247 dbSNP
rs751232934 251 dbSNP
rs1269459790 254 dbSNP
rs957137018 259 dbSNP
rs1414154474 265 dbSNP
rs988326670 267 dbSNP
rs1299853406 274 dbSNP
rs1417460904 277 dbSNP
rs1019763022 279 dbSNP
rs542704210 281 dbSNP
rs559627643 282 dbSNP
rs1164816092 283 dbSNP
rs1215101467 284 dbSNP
rs1478472604 291 dbSNP
rs1265755221 295 dbSNP
rs1250762860 297 dbSNP
rs1485765234 297 dbSNP
rs752356843 299 dbSNP
rs1224067364 300 dbSNP
rs1247443314 300 dbSNP
rs992394274 304 dbSNP
rs950919899 306 dbSNP
rs552217257 307 dbSNP
rs1318584786 309 dbSNP
rs1280046992 314 dbSNP
rs1249602050 317 dbSNP
rs573070213 318 dbSNP
rs867562048 322 dbSNP
rs943391037 329 dbSNP
rs373161729 331 dbSNP
rs1414271906 332 dbSNP
rs1457839858 333 dbSNP
rs748024967 338 dbSNP
rs1164412878 339 dbSNP
rs1426348430 347 dbSNP
rs1169172745 348 dbSNP
rs1428231792 350 dbSNP
rs1426386486 358 dbSNP
rs1348382650 359 dbSNP
rs921630151 361 dbSNP
rs931676934 367 dbSNP
rs984825795 372 dbSNP
rs1039049187 375 dbSNP
rs771715354 377 dbSNP
rs1459166860 385 dbSNP
rs909152886 386 dbSNP
rs371887618 387 dbSNP
rs1373122160 388 dbSNP
rs1052938036 390 dbSNP
rs891643635 391 dbSNP
rs1036182961 393 dbSNP
rs1290827611 394 dbSNP
rs1220980576 395 dbSNP
rs896304856 396 dbSNP
rs1446795352 398 dbSNP
rs1401864780 403 dbSNP
rs1042818284 414 dbSNP
rs905640348 414 dbSNP
rs949511240 415 dbSNP
rs1001291717 416 dbSNP
rs1287250779 416 dbSNP
rs1394664842 416 dbSNP
rs565049559 417 dbSNP
rs1441556722 418 dbSNP
rs959682703 419 dbSNP
rs1045120672 420 dbSNP
rs1256347533 423 dbSNP
rs1211913446 427 dbSNP
rs1026544778 432 dbSNP
rs1302167498 433 dbSNP
rs1040456760 437 dbSNP
rs985330528 441 dbSNP
rs900569246 442 dbSNP
rs965181031 442 dbSNP
rs974785089 442 dbSNP
rs549911444 445 dbSNP
rs1000874985 447 dbSNP
rs1252468497 448 dbSNP
rs933298085 449 dbSNP
rs996663641 451 dbSNP
rs1159456708 453 dbSNP
rs1421820837 460 dbSNP
rs1162003126 461 dbSNP
rs1181241437 461 dbSNP
rs1424494451 462 dbSNP
rs1256721150 463 dbSNP
rs1183542724 464 dbSNP
rs776944946 468 dbSNP
rs1355473930 472 dbSNP
rs1054172828 475 dbSNP
rs1237659462 476 dbSNP
rs1258612410 476 dbSNP
rs1411773789 480 dbSNP
rs1399638221 498 dbSNP
rs1413534922 501 dbSNP
rs1407275489 506 dbSNP
rs1299231687 509 dbSNP
rs879032301 510 dbSNP
rs1402053597 518 dbSNP
rs1165828142 519 dbSNP
rs186131152 519 dbSNP
rs116802199 520 dbSNP
rs1009807813 521 dbSNP
rs1474208653 522 dbSNP
rs1256515727 527 dbSNP
rs759610943 528 dbSNP
rs1019815736 533 dbSNP
rs947315074 535 dbSNP
rs1043323196 536 dbSNP
rs1259152431 536 dbSNP
rs965531771 538 dbSNP
rs1428233101 539 dbSNP
rs937104820 542 dbSNP
rs9914357 544 dbSNP
rs1334818228 545 dbSNP
rs895503502 546 dbSNP
rs549064723 547 dbSNP
rs369145199 548 dbSNP
rs1281900603 552 dbSNP
rs1387631728 554 dbSNP
rs886724927 556 dbSNP
rs1324025381 559 dbSNP
rs1461012131 563 dbSNP
rs1417031162 564 dbSNP
rs1380782081 569 dbSNP
rs1371182881 573 dbSNP
rs192238331 574 dbSNP
rs886053112 575 dbSNP
rs1211222635 576 dbSNP
rs1467662772 576 dbSNP
rs1311837297 577 dbSNP
rs1337851600 582 dbSNP
rs7774 582 dbSNP
rs1270023451 583 dbSNP
rs1339737560 586 dbSNP
rs1301569196 587 dbSNP
rs1440185387 589 dbSNP
rs1401145465 591 dbSNP
rs375660349 592 dbSNP
rs575836707 595 dbSNP
rs761256289 598 dbSNP
rs1394026113 599 dbSNP
rs974816211 601 dbSNP
rs1478245676 602 dbSNP
rs1396466948 606 dbSNP
rs1191366147 608 dbSNP
rs1485280605 609 dbSNP
rs1030332396 610 dbSNP
rs961959749 611 dbSNP
rs971952942 612 dbSNP
rs8834 613 dbSNP
rs886053113 614 dbSNP
rs1347588797 620 dbSNP
rs913226820 622 dbSNP
rs1233922096 626 dbSNP
rs1419143167 627 dbSNP
rs1448015976 628 dbSNP
rs1044836031 630 dbSNP
rs529707167 634 dbSNP
rs1311602893 635 dbSNP
rs1333856152 637 dbSNP
rs1371585584 638 dbSNP
rs1414755162 641 dbSNP
rs1377060107 643 dbSNP
rs886053114 644 dbSNP
rs113366718 645 dbSNP
rs1053818311 646 dbSNP
rs374217615 647 dbSNP
rs1232745105 648 dbSNP
rs1056906243 649 dbSNP
rs1009860660 651 dbSNP
rs777911516 662 dbSNP
rs1278725289 664 dbSNP
rs570601986 670 dbSNP
rs901387561 674 dbSNP
rs1222104053 675 dbSNP
rs997037287 679 dbSNP
rs929703752 682 dbSNP
rs1028883995 684 dbSNP
rs1448739379 688 dbSNP
rs367938507 689 dbSNP
rs112548629 690 dbSNP
rs368116445 692 dbSNP
rs368356907 692 dbSNP
rs538982347 692 dbSNP
rs886053115 692 dbSNP
rs1476493939 694 dbSNP
rs201114697 694 dbSNP
rs767446594 695 dbSNP
rs1213926261 697 dbSNP
rs1346895897 697 dbSNP
rs1233803103 698 dbSNP
rs536198075 698 dbSNP
rs868716574 698 dbSNP
rs1047192623 699 dbSNP
rs1232383678 700 dbSNP
rs1280730146 701 dbSNP
rs1340915193 701 dbSNP
rs536398300 702 dbSNP
rs1210967622 703 dbSNP
rs1462578523 704 dbSNP
rs553081443 704 dbSNP
rs746315302 704 dbSNP
rs796874093 704 dbSNP
rs1053751 705 dbSNP
rs886053116 705 dbSNP
rs1247535619 706 dbSNP
rs996264425 706 dbSNP
rs1053754 707 dbSNP
rs1467199360 707 dbSNP
rs1030446932 708 dbSNP
rs1190772375 708 dbSNP
rs1212412737 709 dbSNP
rs1391100612 710 dbSNP
rs1454162612 712 dbSNP
rs1171323798 715 dbSNP
rs1427927486 717 dbSNP
rs954828720 718 dbSNP
rs1442377687 719 dbSNP
rs1325806615 726 dbSNP
rs953186895 726 dbSNP
rs1006365717 728 dbSNP
rs1356609513 731 dbSNP
rs1168718169 733 dbSNP
rs1436751057 734 dbSNP
rs1320811949 738 dbSNP
rs1195749165 751 dbSNP
rs1369968007 758 dbSNP
rs1452648665 761 dbSNP
rs1252530514 762 dbSNP
rs1015970448 764 dbSNP
rs1434098016 766 dbSNP
rs968720821 772 dbSNP
rs1253026396 773 dbSNP
rs558674000 774 dbSNP
rs927194203 775 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gauucUGGUUCGGAGGAAGGGa 5'
               | ::| :| ||||||| 
Target 5' acuuuAAUGAUUCCCCUUCCCc 3'
 		16 - 37
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM4903825
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / PID14_NS
Location of target site NM_001024937 | 3UTR | ACUGGUUUGAUUUCACUGGAGCCUGCUGGGAACGUGACCUCUGACCCCUGAUGCUUUCGUGAUCACGUGACCAUCCUCUUCCCCAACAUGUCCUCUUCCCAAAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161237
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903827
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / PID14_9124
Location of target site NM_170663 | 3UTR | AUGUCCUCUUCCCAAAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161237
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903828
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / PID21_9124
Location of target site NM_170663 | 3UTR | AUGUCCUCUUCCCAAAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161237
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_001024937 | 3UTR | CUGGUUUGAUUUCACUGGAGCCUGCUGGGAACGUGACCUCUGACCCCUGAUGCUUUCGUGAUCACGUGACCAUCCUCUUCCCCAACAUGUCCUCUUCCCAAAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_015716 | 3UTR | UGCUGGGAACGUGACCUCUGACCCCUGAUGCUUUCGUGAUCACGUGACCAUCCUCUUCCCCAACAUGUCCUCUUCCCAAAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_001024937 | 3UTR | UUUCACUGGAGCCUGCUGGGAACGUGACCUCUGACCCCUGAUGCUUUCGUGAUCACGUGACCAUCCUCUUCCCCAACAUGUCCUCUUCCCAAAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_001024937 | 3UTR | UGGAGCCUGCUGGGAACGUGACCUCUGACCCCUGAUGCUUUCGUGAUCACGUGACCAUCCUCUUCCCCAACAUGUCCUCUUCCCAAAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_170663 | 3UTR | AUCACGUGACCAUCCUCUUCCCCAACAUGUCCUCUUCCCAAAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_170663 | 3UTR | CCUGAUGCUUUCGUGAUCACGUGACCAUCCUCUUCCCCAACAUGUCCUCUUCCCAAAACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 10 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000347992.7 | 3UTR | UCAUUUUCUGAAAGCACUUUAAUGAUUCCCCUUCCCCCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
215 hsa-miR-4747-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061689 BTG2 BTG anti-proliferation factor 2 2 2
MIRT062834 BCL7A BCL tumor suppressor 7A 2 2
MIRT079371 CCDC137 coiled-coil domain containing 137 2 2
MIRT081190 MIDN midnolin 2 4
MIRT081724 ZNF507 zinc finger protein 507 2 2
MIRT110565 ZMYND11 zinc finger MYND-type containing 11 2 2
MIRT133724 SKI SKI proto-oncogene 2 4
MIRT146689 MINK1 misshapen like kinase 1 2 2
MIRT150676 SLC27A1 solute carrier family 27 member 1 2 2
MIRT159196 NRBP1 nuclear receptor binding protein 1 2 2
MIRT180865 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT190659 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT196111 MPRIP myosin phosphatase Rho interacting protein 2 2
MIRT232390 SP1 Sp1 transcription factor 2 2
MIRT331070 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 4
MIRT338632 SHMT2 serine hydroxymethyltransferase 2 2 2
MIRT407441 CTDSP1 CTD small phosphatase 1 2 2
MIRT444276 NKX6-1 NK6 homeobox 1 2 2
MIRT444834 PDE6D phosphodiesterase 6D 2 2
MIRT445452 EXT1 exostosin glycosyltransferase 1 2 2
MIRT445644 NPY4R neuropeptide Y receptor Y4 2 2
MIRT446157 RPL12 ribosomal protein L12 2 2
MIRT446608 HIP1 huntingtin interacting protein 1 2 2
MIRT447108 CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2 2
MIRT449314 MRO maestro 2 2
MIRT450305 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT451245 ZNF444 zinc finger protein 444 2 2
MIRT451714 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT451908 ILK integrin linked kinase 2 2
MIRT452183 KIAA1456 KIAA1456 2 2
MIRT452610 REPIN1 replication initiator 1 2 2
MIRT453422 GLG1 golgi glycoprotein 1 2 2
MIRT454006 ALKBH5 alkB homolog 5, RNA demethylase 2 2
MIRT455072 ARHGAP39 Rho GTPase activating protein 39 2 2
MIRT455319 TTLL9 tubulin tyrosine ligase like 9 2 2
MIRT455357 KDM5C lysine demethylase 5C 2 2
MIRT455589 TAF12 TATA-box binding protein associated factor 12 2 2
MIRT455711 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT455860 TMEM254 transmembrane protein 254 2 2
MIRT455919 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT455946 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT456935 LRP10 LDL receptor related protein 10 2 2
MIRT457223 AP3D1 adaptor related protein complex 3 delta 1 subunit 2 2
MIRT457431 NOL10 nucleolar protein 10 2 2
MIRT457470 SLC35F6 solute carrier family 35 member F6 2 2
MIRT457907 ZNF212 zinc finger protein 212 2 2
MIRT458046 TSEN54 tRNA splicing endonuclease subunit 54 2 2
MIRT458073 RNLS renalase, FAD dependent amine oxidase 2 2
MIRT458234 NXPH3 neurexophilin 3 2 2
MIRT458307 TNFAIP8L3 TNF alpha induced protein 8 like 3 2 2
MIRT458378 ITM2C integral membrane protein 2C 2 2
MIRT458967 ZNF436 zinc finger protein 436 2 2
MIRT459099 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT459446 TMEM37 transmembrane protein 37 2 2
MIRT459671 VPS37C VPS37C, ESCRT-I subunit 2 2
MIRT460727 ASXL3 additional sex combs like 3, transcriptional regulator 2 2
MIRT460744 SRP14 signal recognition particle 14 2 2
MIRT461531 C14orf1 ergosterol biosynthesis 28 homolog 2 2
MIRT461752 DDX11 DEAD/H-box helicase 11 2 2
MIRT461837 F2RL3 F2R like thrombin or trypsin receptor 3 2 2
MIRT462019 RIF1 replication timing regulatory factor 1 2 2
MIRT462631 PHF5A PHD finger protein 5A 2 2
MIRT462772 ZNF8 zinc finger protein 8 2 2
MIRT463032 ZNF689 zinc finger protein 689 2 2
MIRT463886 WNT7B Wnt family member 7B 2 2
MIRT463995 WDTC1 WD and tetratricopeptide repeats 1 2 2
MIRT464371 URM1 ubiquitin related modifier 1 2 2
MIRT465342 TPM3 tropomyosin 3 2 4
MIRT465515 PRICKLE4 prickle planar cell polarity protein 4 2 2
MIRT465602 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT465697 TNPO2 transportin 2 2 10
MIRT466988 SSRP1 structure specific recognition protein 1 2 4
MIRT467630 SLC7A5 solute carrier family 7 member 5 2 2
MIRT468132 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT468322 SF3B3 splicing factor 3b subunit 3 2 2
MIRT468502 SESN2 sestrin 2 2 2
MIRT468881 RREB1 ras responsive element binding protein 1 2 2
MIRT469322 RGP1 RGP1 homolog, RAB6A GEF complex partner 1 2 2
MIRT469562 RARA retinoic acid receptor alpha 2 2
MIRT469898 PTRF caveolae associated protein 1 2 2
MIRT470045 PTGFRN prostaglandin F2 receptor inhibitor 2 2
MIRT470068 PTGES2 prostaglandin E synthase 2 2 2
MIRT470238 PRRC2A proline rich coiled-coil 2A 2 2
MIRT470390 PPP1R16B protein phosphatase 1 regulatory subunit 16B 2 2
MIRT470500 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT470689 POLR2D RNA polymerase II subunit D 2 2
MIRT470704 POGK pogo transposable element derived with KRAB domain 2 2
MIRT471083 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta 2 2
MIRT472482 NACC2 NACC family member 2 2 2
MIRT473583 MAT2A methionine adenosyltransferase 2A 2 2
MIRT474554 KLHDC3 kelch domain containing 3 2 2
MIRT474651 KLF13 Kruppel like factor 13 2 2
MIRT474843 KHSRP KH-type splicing regulatory protein 2 2
MIRT474934 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT475573 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2 2
MIRT476045 GRSF1 G-rich RNA sequence binding factor 1 2 2
MIRT476080 GRB2 growth factor receptor bound protein 2 2 2
MIRT476440 GBA2 glucosylceramidase beta 2 2 2
MIRT476764 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 2
MIRT478785 CRTC2 CREB regulated transcription coactivator 2 2 2
MIRT479287 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT479505 CDH6 cadherin 6 2 2
MIRT479732 CCND1 cyclin D1 2 6
MIRT480352 C5orf24 chromosome 5 open reading frame 24 2 2
MIRT480407 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT480859 BHLHB9 basic helix-loop-helix family member b9 2 2
MIRT481445 ARRB2 arrestin beta 2 2 2
MIRT481732 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT481824 AP2M1 adaptor related protein complex 2 mu 1 subunit 2 2
MIRT482566 ABHD2 abhydrolase domain containing 2 2 2
MIRT482607 ABHD14B abhydrolase domain containing 14B 2 2
MIRT483144 SYCE1L synaptonemal complex central element protein 1 like 2 2
MIRT483214 APOA1 apolipoprotein A1 2 6
MIRT483878 TGIF1 TGFB induced factor homeobox 1 2 2
MIRT483917 SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2 2
MIRT483939 LENG8 leukocyte receptor cluster member 8 2 4
MIRT484420 SNX19 sorting nexin 19 2 2
MIRT484489 SLC9A1 solute carrier family 9 member A1 2 2
MIRT484612 SIX3 SIX homeobox 3 2 6
MIRT484705 RNF11 ring finger protein 11 2 2
MIRT485107 SHISA6 shisa family member 6 2 2
MIRT485354 MYO1C myosin IC 2 4
MIRT485609 FOSL1 FOS like 1, AP-1 transcription factor subunit 2 4
MIRT487311 GLTSCR1 BRD4 interacting chromatin remodeling complex associated protein 2 2
MIRT487417 CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 2 2
MIRT487695 CDK14 cyclin dependent kinase 14 2 2
MIRT487791 GPR20 G protein-coupled receptor 20 2 4
MIRT488042 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 2
MIRT488058 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 2
MIRT488237 DNLZ DNL-type zinc finger 2 4
MIRT488764 FXYD1 FXYD domain containing ion transport regulator 1 2 2
MIRT489401 TUBB2A tubulin beta 2A class IIa 2 2
MIRT489777 GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 2 2
MIRT490099 FN3K fructosamine 3 kinase 2 2
MIRT490290 ISL2 ISL LIM homeobox 2 2 2
MIRT490378 LHFPL3 LHFPL tetraspan subfamily member 3 2 2
MIRT491329 GFER growth factor, augmenter of liver regeneration 2 2
MIRT491435 MSX2 msh homeobox 2 2 2
MIRT491769 ZNF385A zinc finger protein 385A 2 2
MIRT491922 WNK2 WNK lysine deficient protein kinase 2 2 2
MIRT491983 UNK unkempt family zinc finger 2 2
MIRT492228 SLC48A1 solute carrier family 48 member 1 2 2
MIRT492404 SDK1 sidekick cell adhesion molecule 1 2 2
MIRT492767 PDGFB platelet derived growth factor subunit B 2 2
MIRT492966 NCS1 neuronal calcium sensor 1 2 2
MIRT493295 LLGL2 LLGL2, scribble cell polarity complex component 2 2
MIRT493650 HDLBP high density lipoprotein binding protein 2 2
MIRT493913 FAM127B retrotransposon Gag like 8A 2 4
MIRT495601 NKX2-5 NK2 homeobox 5 2 2
MIRT496875 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT498514 MYH14 myosin heavy chain 14 2 2
MIRT499178 RBPJL recombination signal binding protein for immunoglobulin kappa J region like 2 2
MIRT502143 KIF5B kinesin family member 5B 2 8
MIRT502692 CSNK1G1 casein kinase 1 gamma 1 2 4
MIRT508460 HOXB6 homeobox B6 2 4
MIRT510430 ZNF207 zinc finger protein 207 2 6
MIRT511837 GPATCH8 G-patch domain containing 8 2 4
MIRT512368 CPM carboxypeptidase M 2 2
MIRT512506 BTBD19 BTB domain containing 19 2 2
MIRT513065 ANKRD45 ankyrin repeat domain 45 2 2
MIRT513267 SCUBE1 signal peptide, CUB domain and EGF like domain containing 1 2 4
MIRT513575 EVX1 even-skipped homeobox 1 2 2
MIRT515051 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT515790 COL4A3BP collagen type IV alpha 3 binding protein 2 2
MIRT521657 PRKD3 protein kinase D3 2 2
MIRT522679 LUZP1 leucine zipper protein 1 2 6
MIRT528845 RAB32 RAB32, member RAS oncogene family 2 2
MIRT533569 TOR1AIP1 torsin 1A interacting protein 1 2 2
MIRT543738 DHCR7 7-dehydrocholesterol reductase 2 2
MIRT544295 TSPYL1 TSPY like 1 2 2
MIRT544857 MYH2 myosin heavy chain 2 2 4
MIRT557323 HIATL1 major facilitator superfamily domain containing 14B 2 4
MIRT560522 TMEM98 transmembrane protein 98 2 2
MIRT561565 SLC6A9 solute carrier family 6 member 9 2 2
MIRT562374 ERI2 ERI1 exoribonuclease family member 2 2 2
MIRT565780 SEMA6D semaphorin 6D 2 2
MIRT569548 UNC119B unc-119 lipid binding chaperone B 2 2
MIRT569944 PRRT2 proline rich transmembrane protein 2 2 2
MIRT570016 COL1A2 collagen type I alpha 2 chain 2 2
MIRT572163 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT572322 HSPB6 heat shock protein family B (small) member 6 2 2
MIRT573495 IQSEC3 IQ motif and Sec7 domain 3 2 2
MIRT574139 MARVELD1 MARVEL domain containing 1 2 2
MIRT609449 CCDC149 coiled-coil domain containing 149 2 2
MIRT610619 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT623355 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT629854 ACOX1 acyl-CoA oxidase 1 2 2
MIRT630516 CDC73 cell division cycle 73 2 2
MIRT632535 PSMB2 proteasome subunit beta 2 2 2
MIRT633975 SLC35E2 solute carrier family 35 member E2 2 2
MIRT636408 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT641722 LTBR lymphotoxin beta receptor 2 2
MIRT642661 RGS6 regulator of G protein signaling 6 2 2
MIRT649649 MAST3 microtubule associated serine/threonine kinase 3 2 2
MIRT650367 MOCS3 molybdenum cofactor synthesis 3 2 2
MIRT651355 ZBTB40 zinc finger and BTB domain containing 40 2 2
MIRT664840 HUS1 HUS1 checkpoint clamp component 2 2
MIRT667322 MYH9 myosin heavy chain 9 2 2
MIRT670680 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT674922 TRPM6 transient receptor potential cation channel subfamily M member 6 2 2
MIRT675919 CYP51A1 cytochrome P450 family 51 subfamily A member 1 2 2
MIRT676493 GJD3 gap junction protein delta 3 2 2
MIRT680162 ZDHHC20 zinc finger DHHC-type containing 20 2 2
MIRT688008 GSN gelsolin 2 2
MIRT688997 ATP6AP1 ATPase H+ transporting accessory protein 1 2 2
MIRT700337 RAB4A RAB4A, member RAS oncogene family 2 2
MIRT701344 NR4A3 nuclear receptor subfamily 4 group A member 3 2 2
MIRT703519 FKBP15 FK506 binding protein 15 2 2
MIRT703901 EPT1 selenoprotein I 2 2
MIRT705565 ARHGEF18 Rho/Rac guanine nucleotide exchange factor 18 2 2
MIRT709709 DNAJC11 DnaJ heat shock protein family (Hsp40) member C11 2 2
MIRT713108 TMBIM4 transmembrane BAX inhibitor motif containing 4 2 2
MIRT718426 ZNF85 zinc finger protein 85 2 2
MIRT719236 CYSLTR2 cysteinyl leukotriene receptor 2 2 2
MIRT719326 STAC SH3 and cysteine rich domain 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4747 Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-4747-5p Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-4747-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4747-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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