miRTarBase - #MIRT149892


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pre-miRNA Information
pre-miRNA hsa-mir-1185-1   
Genomic Coordinates chr14: 101042977 - 101043062
Synonyms MIRN1185-1, hsa-mir-1185-1, MIR1185-1
Description Homo sapiens miR-1185-1 stem-loop
Comment This sequence was proposed as a miRNA candidate by Berezikov et al by RAKE analysis .
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-1185-1-3p
Sequence 53| AUAUACAGGGGGAGACUCUUAU |74
Evidence Not_experimental
Experiments
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 5 14 + 101043033 29233923 MiREDiBase
A-to-I 7 14 + 101043035 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs749794228 1 dbSNP
rs369414498 4 dbSNP
rs771096180 5 dbSNP
rs774958411 7 dbSNP
rs1226171972 11 dbSNP
rs1449899083 14 dbSNP
rs761183893 16 dbSNP
rs1380874583 20 dbSNP
rs771625921 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol LDLR   
Synonyms FH, FHC, LDLCQ2
Description low density lipoprotein receptor
Transcript NM_000527   
Expression
Putative miRNA Targets on LDLR
3'UTR of LDLR
(miRNA target sites are highlighted)		 
>LDLR|NM_000527|3'UTR
   1 ACATCTGCCTGGAGTCCCGTCCCTGCCCAGAACCCTTCCTGAGACCTCGCCGGCCTTGTTTTATTCAAAGACAGAGAAGA
  81 CCAAAGCATTGCCTGCCAGAGCTTTGTTTTATATATTTATTCATCTGGGAGGCAGAACAGGCTTCGGACAGTGCCCATGC
 161 AATGGCTTGGGTTGGGATTTTGGTTTCTTCCTTTCCTCGTGAAGGATAAGAGAAACAGGCCCGGGGGGACCAGGATGACA
 241 CCTCCATTTCTCTCCAGGAAGTTTTGAGTTTCTCTCCACCGTGACACAATCCTCAAACATGGAAGATGAAAGGGGAGGGG
 321 ATGTCAGGCCCAGAGAAGCAAGTGGCTTTCAACACACAACAGCAGATGGCACCAACGGGACCCCCTGGCCCTGCCTCATC
 401 CACCAATCTCTAAGCCAAACCCCTAAACTCAGGAGTCAACGTGTTTACCTCTTCTATGCAAGCCTTGCTAGACAGCCAGG
 481 TTAGCCTTTGCCCTGTCACCCCCGAATCATGACCCACCCAGTGTCTTTCGAGGTGGGTTTGTACCTTCCTTAAGCCAGGA
 561 AAGGGATTCATGGCGTCGGAAATGATCTGGCTGAATCCGTGGTGGCACCGAGACCAAACTCATTCACCAAATGATGCCAC
 641 TTCCCAGAGGCAGAGCCTGAGTCACTGGTCACCCTTAATATTTATTAAGTGCCTGAGACACCCGGTTACCTTGGCCGTGA
 721 GGACACGTGGCCTGCACCCAGGTGTGGCTGTCAGGACACCAGCCTGGTGCCCATCCTCCCGACCCCTACCCACTTCCATT
 801 CCCGTGGTCTCCTTGCACTTTCTCAGTTCAGAGTTGTACACTGTGTACATTTGGCATTTGTGTTATTATTTTGCACTGTT
 881 TTCTGTCGTGTGTGTTGGGATGGGATCCCAGGCCAGGGAAAGCCCGTGTCAATGAATGCCGGGGACAGAGAGGGGCAGGT
 961 TGACCGGGACTTCAAAGCCGTGATCGTGAATATCGAGAACTGCCATTGTCGTCTTTATGTCCGCCCACCTAGTGCTTCCA
1041 CTTCTATGCAAATGCCTCCAAGCCATTCACTTCCCCAATCTTGTCGTTGATGGGTATGTGTTTAAAACATGCACGGTGAG
1121 GCCGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAGGAGATCGAG
1201 ACCATCCTGGCTAACACGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCACCTGTAG
1281 TCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGAACCCGGGAAGCGGAGCTTGCAGTGAGCCGAGATTGCGCCA
1361 CTGCAGTCCGCAGTCTGGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAACAAAAAAAAACCATGCATGGTG
1441 CATCAGCAGCCCATGGCCTCTGGCCAGGCATGGCGAGGCTGAGGTGGGAGGATGGTTTGAGCTCAGGCATTTGAGGCTGT
1521 CGTGAGCTATGATTATGCCACTGCTTTCCAGCCTGGGCAACATAGTAAGACCCCATCTCTTAAAAAATGAATTTGGCCAG
1601 ACACAGGTGCCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGCTGGATCACTTGAGTTCAGGAGTTGGAGACCAGG
1681 CCTGAGCAACAAAGCGAGATCCCATCTCTACAAAAACCAAAAAGTTAAAAATCAGCTGGGTACGGTGGCACGTGCCTGTG
1761 ATCCCAGCTACTTGGGAGGCTGAGGCAGGAGGATCGCCTGAGCCCAGGAGGTGGAGGTTGCAGTGAGCCATGATCGAGCC
1841 ACTGCACTCCAGCCTGGGCAACAGATGAAGACCCTATTTCAGAAATACAACTATAAAAAAATAAATAAATCCTCCAGTCT
1921 GGATCGTTTGACGGGACTTCAGGTTCTTTCTGAAATCGCCGTGTTACTGTTGCACTGATGTCCGGAGAGACAGTGACAGC
2001 CTCCGTCAGACTCCCGCGTGAAGATGTCACAAGGGATTGGCAATTGTCCCCAGGGACAAAACACTGTGTCCCCCCCAGTG
2081 CAGGGAACCGTGATAAGCCTTTCTGGTTTCGGAGCACGTAAATGCGTCCCTGTACAGATAGTGGGGATTTTTTGTTATGT
2161 TTGCACTTTGTATATTGGTTGAAACTGTTATCACTTATATATATATATATACACACATATATATAAAATCTATTTATTTT
2241 TGCAAACCCTGGTTGCTGTATTTGTTCAGTGACTATTCTCGGGGCCCTGTGTAGGGGGTTATTGCCTCTGAAATGCCTCT
2321 TCTTTATGTACAAAGATTATTTGCACGAACTGGACTGTGTGCAACGCTTTTTGGGAGAATGATGTCCCCGTTGTATGTAT
2401 GAGTGGCTTCTGGGAGATGGGTGTCACTTTTTAAACCACTGTATAGAAGGTTTTTGTAGCCTGAATGTCTTACTGTGATC
2481 AATTAAATTTCTTAAATGAACCAATTTGTCTAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uauUCUCAGAGGGGGACAUAUa 5'
             |||||: : | ||||:|| 
Target 5' ttcAGAGTTGTACACTGTGTAc 3'
 827 - 848 147.00 -13.00
2 
miRNA  3' uauucucagagGGGGACAUAUa 5'
                     || ||||||| 
Target 5' cactttttaaaCCACTGTATAg 3'
 2425 - 2446 147.00 -9.20
3 
miRNA  3' uauucUCAGAG---GGGGACAUAUa 5'
               | ||||    ||||||:|| 
Target 5' tgactATTCTCGGGGCCCTGTGTAg 3'
 2270 - 2294 141.00 -14.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
918887 2 ClinVar
265909 14 ClinVar
630614 20 ClinVar
251226 44 ClinVar
265910 53 ClinVar
328056 142 ClinVar
328057 170 ClinVar
889308 224 ClinVar
889309 288 ClinVar
328058 316 ClinVar
328059 339 ClinVar
328060 373 ClinVar
328061 377 ClinVar
328062 421 ClinVar
328063 504 ClinVar
328064 505 ClinVar
889991 518 ClinVar
328065 524 ClinVar
889992 534 ClinVar
328066 564 ClinVar
328067 580 ClinVar
328068 585 ClinVar
328069 654 ClinVar
328070 667 ClinVar
891550 705 ClinVar
891551 717 ClinVar
328071 768 ClinVar
328072 774 ClinVar
328073 785 ClinVar
684566 804 ClinVar
328074 805 ClinVar
328075 809 ClinVar
891809 850 ClinVar
328076 855 ClinVar
328077 943 ClinVar
328078 947 ClinVar
891810 966 ClinVar
891811 967 ClinVar
328079 980 ClinVar
328080 983 ClinVar
328081 995 ClinVar
891812 996 ClinVar
889364 1041 ClinVar
889365 1131 ClinVar
328082 1132 ClinVar
328083 1134 ClinVar
328084 1141 ClinVar
328085 1154 ClinVar
889366 1168 ClinVar
328086 1169 ClinVar
890058 1174 ClinVar
328087 1216 ClinVar
328088 1218 ClinVar
890059 1228 ClinVar
328089 1232 ClinVar
328090 1257 ClinVar
328091 1263 ClinVar
328092 1269 ClinVar
890060 1270 ClinVar
328093 1293 ClinVar
328094 1333 ClinVar
328095 1337 ClinVar
328096 1341 ClinVar
328097 1355 ClinVar
328098 1357 ClinVar
891604 1370 ClinVar
328099 1377 ClinVar
891605 1378 ClinVar
891606 1394 ClinVar
891873 1418 ClinVar
328100 1420 ClinVar
328101 1431 ClinVar
891874 1431 ClinVar
328102 1454 ClinVar
328103 1511 ClinVar
891875 1551 ClinVar
891876 1559 ClinVar
889426 1562 ClinVar
328104 1601 ClinVar
328105 1610 ClinVar
328106 1744 ClinVar
889427 1745 ClinVar
328107 1753 ClinVar
328108 1763 ClinVar
328109 1794 ClinVar
328110 1832 ClinVar
328111 1859 ClinVar
328112 1896 ClinVar
328113 1917 ClinVar
328114 1918 ClinVar
328115 1932 ClinVar
328116 1961 ClinVar
890101 1962 ClinVar
890102 2005 ClinVar
328117 2017 ClinVar
328118 2055 ClinVar
328119 2070 ClinVar
890103 2112 ClinVar
890104 2127 ClinVar
890105 2133 ClinVar
328120 2174 ClinVar
328121 2196 ClinVar
328122 2196 ClinVar
328123 2209 ClinVar
328124 2211 ClinVar
890680 2211 ClinVar
328125 2252 ClinVar
890681 2283 ClinVar
328126 2320 ClinVar
890682 2351 ClinVar
328127 2366 ClinVar
328128 2367 ClinVar
328129 2385 ClinVar
COSN21051196 12 COSMIC
COSN31975863 36 COSMIC
COSN15304446 53 COSMIC
COSN22375529 64 COSMIC
COSN31599944 87 COSMIC
COSN30524511 114 COSMIC
COSN13779131 115 COSMIC
COSN31561204 126 COSMIC
COSN15634489 142 COSMIC
COSN26569551 146 COSMIC
COSN30137765 200 COSMIC
COSN28725835 316 COSMIC
COSN24572525 445 COSMIC
COSN28658844 667 COSMIC
COSN17037621 763 COSMIC
COSN28673675 774 COSMIC
rs2738464 316 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs773170427 3 dbSNP
rs762784474 4 dbSNP
rs72658871 14 dbSNP
rs371804196 19 dbSNP
rs56270417 20 dbSNP
rs545437018 21 dbSNP
rs766917684 24 dbSNP
rs1234931640 25 dbSNP
rs1185819720 26 dbSNP
rs72658872 29 dbSNP
rs1461282475 34 dbSNP
rs763725187 37 dbSNP
rs966455007 41 dbSNP
rs879254527 44 dbSNP
rs1205723861 47 dbSNP
rs1408117816 49 dbSNP
rs17243004 50 dbSNP
rs755797548 52 dbSNP
rs14158 53 dbSNP
rs746245206 58 dbSNP
rs1315160655 67 dbSNP
rs1398411835 67 dbSNP
rs374945549 69 dbSNP
rs773717642 69 dbSNP
rs758695681 75 dbSNP
rs1414365663 77 dbSNP
rs1280314446 80 dbSNP
rs761573909 81 dbSNP
rs780676892 82 dbSNP
rs747457496 83 dbSNP
rs1243420096 87 dbSNP
rs768828593 89 dbSNP
rs776540572 96 dbSNP
rs748196009 102 dbSNP
rs1039733927 103 dbSNP
rs770159026 113 dbSNP
rs1233039967 115 dbSNP
rs1317252841 119 dbSNP
rs1470882424 129 dbSNP
rs1400966015 131 dbSNP
rs553019832 132 dbSNP
rs773506427 136 dbSNP
rs762842582 141 dbSNP
rs3826810 142 dbSNP
rs774399171 144 dbSNP
rs1374060162 146 dbSNP
rs1434433343 147 dbSNP
rs1038174435 151 dbSNP
rs759363483 153 dbSNP
rs767452364 154 dbSNP
rs1279013982 155 dbSNP
rs1376124751 156 dbSNP
rs1355613354 158 dbSNP
rs1234969609 160 dbSNP
rs1209880267 163 dbSNP
rs1270449809 167 dbSNP
rs1448966538 168 dbSNP
rs886054157 170 dbSNP
rs1305478751 171 dbSNP
rs1287907174 183 dbSNP
rs1487074534 184 dbSNP
rs1047249425 189 dbSNP
rs1345490895 192 dbSNP
rs34890611 192 dbSNP
rs752228709 199 dbSNP
rs529666063 200 dbSNP
rs918630095 202 dbSNP
rs1269103318 205 dbSNP
rs1201882697 207 dbSNP
rs1236996978 208 dbSNP
rs1037491334 211 dbSNP
rs898918795 213 dbSNP
rs755564723 215 dbSNP
rs56263043 218 dbSNP
rs763742059 219 dbSNP
rs775160734 220 dbSNP
rs970591604 222 dbSNP
rs1165817060 223 dbSNP
rs1448226030 223 dbSNP
rs17243011 224 dbSNP
rs758854149 226 dbSNP
rs780257440 229 dbSNP
rs1443125642 231 dbSNP
rs1476427860 240 dbSNP
rs1327851898 242 dbSNP
rs1245265296 243 dbSNP
rs1368694352 245 dbSNP
rs1232340672 246 dbSNP
rs1030770956 247 dbSNP
rs956603752 262 dbSNP
rs1341083516 265 dbSNP
rs1045679023 269 dbSNP
rs568538528 278 dbSNP
rs1468549333 281 dbSNP
rs72658873 282 dbSNP
rs907221420 288 dbSNP
rs1001791219 290 dbSNP
rs1363424890 290 dbSNP
rs1194396386 295 dbSNP
rs1244226939 300 dbSNP
rs1056485811 301 dbSNP
rs1170258709 302 dbSNP
rs1418768334 308 dbSNP
rs1463144392 311 dbSNP
rs781686110 312 dbSNP
rs748248927 313 dbSNP
rs1367545960 314 dbSNP
rs2738464 316 dbSNP
rs1318840516 320 dbSNP
rs773631029 321 dbSNP
rs532336880 324 dbSNP
rs749503077 325 dbSNP
rs1277184654 326 dbSNP
rs1335068442 330 dbSNP
rs1234654805 335 dbSNP
rs1270698036 336 dbSNP
rs17249029 339 dbSNP
rs1206263668 342 dbSNP
rs1481350603 360 dbSNP
rs539448338 361 dbSNP
rs1198738911 367 dbSNP
rs886054158 373 dbSNP
rs1480900329 376 dbSNP
rs35740761 377 dbSNP
rs886054159 377 dbSNP
rs941506263 378 dbSNP
rs13306508 379 dbSNP
rs1029310311 380 dbSNP
rs1479533551 381 dbSNP
rs551455738 383 dbSNP
rs1038947613 388 dbSNP
rs955252041 391 dbSNP
rs1309141874 394 dbSNP
rs1398543830 402 dbSNP
rs1222312035 404 dbSNP
rs1297925918 407 dbSNP
rs1323809323 408 dbSNP
rs111252880 409 dbSNP
rs1225935211 412 dbSNP
rs746014399 421 dbSNP
rs1343748559 426 dbSNP
rs768511996 428 dbSNP
rs962660703 442 dbSNP
rs1470307344 448 dbSNP
rs1431806571 450 dbSNP
rs1030950454 453 dbSNP
rs892384466 456 dbSNP
rs563455497 457 dbSNP
rs566969425 458 dbSNP
rs1010699612 460 dbSNP
rs779622318 470 dbSNP
rs534018759 480 dbSNP
rs13306509 493 dbSNP
rs553181858 502 dbSNP
rs574677226 504 dbSNP
rs2738465 505 dbSNP
rs928645831 515 dbSNP
rs1202555241 517 dbSNP
rs115882455 518 dbSNP
rs1055802884 520 dbSNP
rs886054160 524 dbSNP
rs893357780 530 dbSNP
rs1315922139 531 dbSNP
rs771870462 534 dbSNP
rs1041897795 549 dbSNP
rs1336646731 559 dbSNP
rs1453547662 560 dbSNP
rs886054161 564 dbSNP
rs1197269237 572 dbSNP
rs1376985414 575 dbSNP
rs903377930 576 dbSNP
rs1453346985 577 dbSNP
rs1159146958 578 dbSNP
rs1410473697 579 dbSNP
rs886054162 580 dbSNP
rs144675877 583 dbSNP
rs772754135 585 dbSNP
rs1182885176 586 dbSNP
rs1029858553 597 dbSNP
rs1257702922 598 dbSNP
rs1202805603 599 dbSNP
rs1366656009 600 dbSNP
rs955157314 611 dbSNP
rs545799953 615 dbSNP
rs760162975 625 dbSNP
rs916096453 628 dbSNP
rs947785651 642 dbSNP
rs1247384446 650 dbSNP
rs1044829543 651 dbSNP
rs906199137 652 dbSNP
rs563911564 654 dbSNP
rs1386029294 655 dbSNP
rs1290839082 656 dbSNP
rs1421335501 657 dbSNP
rs1017957205 659 dbSNP
rs1162658526 665 dbSNP
rs1052533174 666 dbSNP
rs1433099 667 dbSNP
rs1427406786 668 dbSNP
rs1011252578 669 dbSNP
rs1022115298 673 dbSNP
rs1489696395 681 dbSNP
rs1291532174 682 dbSNP
rs1350835746 687 dbSNP
rs899706512 696 dbSNP
rs973989333 703 dbSNP
rs1250120157 704 dbSNP
rs918417347 705 dbSNP
rs1292043796 708 dbSNP
rs548236850 710 dbSNP
rs1298047082 711 dbSNP
rs1361400627 714 dbSNP
rs951251390 717 dbSNP
rs17243018 718 dbSNP
rs1424991969 721 dbSNP
rs1392879289 726 dbSNP
rs928671935 727 dbSNP
rs568219285 728 dbSNP
rs561985820 733 dbSNP
rs1373122365 734 dbSNP
rs1172132110 736 dbSNP
rs955445720 737 dbSNP
rs991871021 742 dbSNP
rs1016026241 743 dbSNP
rs1453669343 746 dbSNP
rs1249094145 748 dbSNP
rs886054163 768 dbSNP
rs2738466 774 dbSNP
rs1340632616 776 dbSNP
rs947603051 778 dbSNP
rs1042028681 779 dbSNP
rs903341912 781 dbSNP
rs1221704622 782 dbSNP
rs886054164 785 dbSNP
rs17242677 804 dbSNP
rs886054165 805 dbSNP
rs1405394420 807 dbSNP
rs562862170 809 dbSNP
rs981581812 810 dbSNP
rs1390769729 814 dbSNP
rs1051939027 817 dbSNP
rs927677108 818 dbSNP
rs939122382 823 dbSNP
rs890845080 831 dbSNP
rs1006653969 838 dbSNP
rs533410799 849 dbSNP
rs1052078773 850 dbSNP
rs886054166 855 dbSNP
rs913587655 863 dbSNP
rs1362450495 872 dbSNP
rs946652321 873 dbSNP
rs1018344856 876 dbSNP
rs1374100901 879 dbSNP
rs551784908 883 dbSNP
rs1240502680 887 dbSNP
rs1201927366 888 dbSNP
rs180925667 888 dbSNP
rs534345019 889 dbSNP
rs898190149 893 dbSNP
rs1264042483 905 dbSNP
rs17243025 908 dbSNP
rs567716996 926 dbSNP
rs142953361 927 dbSNP
rs1242375210 938 dbSNP
rs375768277 941 dbSNP
rs981660023 942 dbSNP
rs886054167 943 dbSNP
rs886054168 947 dbSNP
rs370513353 950 dbSNP
rs1449889866 964 dbSNP
rs72658874 966 dbSNP
rs991614293 967 dbSNP
rs368246278 974 dbSNP
rs1004735700 978 dbSNP
rs575645180 979 dbSNP
rs886054169 980 dbSNP
rs539332003 981 dbSNP
rs10409044 983 dbSNP
rs1023137968 986 dbSNP
rs572739101 987 dbSNP
rs189408873 995 dbSNP
rs933578781 998 dbSNP
rs1185663904 1008 dbSNP
rs1368295902 1009 dbSNP
rs561450427 1011 dbSNP
rs928820502 1012 dbSNP
rs1170205444 1023 dbSNP
rs1284296102 1024 dbSNP
rs1398665908 1025 dbSNP
rs1449503624 1027 dbSNP
rs1343143553 1033 dbSNP
rs1317183739 1039 dbSNP
rs1052334287 1041 dbSNP
rs763543379 1043 dbSNP
rs1362812284 1044 dbSNP
rs1464653117 1044 dbSNP
rs889318331 1045 dbSNP
rs960474259 1048 dbSNP
rs574545882 1050 dbSNP
rs1183737046 1056 dbSNP
rs1474459609 1066 dbSNP
rs1241792592 1073 dbSNP
rs1336766327 1075 dbSNP
rs544415188 1076 dbSNP
rs1039489968 1085 dbSNP
rs898258959 1086 dbSNP
rs562725399 1087 dbSNP
rs1290505061 1092 dbSNP
rs1229597170 1093 dbSNP
rs995096461 1095 dbSNP
rs1269271919 1096 dbSNP
rs921160736 1098 dbSNP
rs1341937133 1099 dbSNP
rs932571387 1110 dbSNP
rs1050904721 1111 dbSNP
rs796779445 1113 dbSNP
rs886999810 1115 dbSNP
rs1002822403 1116 dbSNP
rs1229266309 1120 dbSNP
rs1035917105 1124 dbSNP
rs868141515 1125 dbSNP
rs533706213 1128 dbSNP
rs1266961929 1129 dbSNP
rs958607333 1131 dbSNP
rs886054170 1132 dbSNP
rs181377148 1134 dbSNP
rs1247272425 1138 dbSNP
rs1021681712 1140 dbSNP
rs367606490 1141 dbSNP
rs1271708936 1146 dbSNP
rs1305653539 1146 dbSNP
rs886054171 1154 dbSNP
rs1218652926 1157 dbSNP
rs1484260163 1159 dbSNP
rs1199016973 1168 dbSNP
rs17242683 1169 dbSNP
rs1404776098 1173 dbSNP
rs17249379 1174 dbSNP
rs567778029 1183 dbSNP
rs955115279 1184 dbSNP
rs1354401903 1185 dbSNP
rs987763356 1195 dbSNP
rs910707801 1198 dbSNP
rs1477750488 1199 dbSNP
rs1177757604 1203 dbSNP
rs531825277 1204 dbSNP
rs1467247139 1213 dbSNP
rs1430841283 1216 dbSNP
rs34113544 1216 dbSNP
rs376570456 1217 dbSNP
rs3180023 1218 dbSNP
rs1192662925 1219 dbSNP
rs1037555185 1224 dbSNP
rs1301913379 1226 dbSNP
rs1198787723 1227 dbSNP
rs72658875 1228 dbSNP
rs557775030 1229 dbSNP
rs1316099627 1232 dbSNP
rs398059563 1232 dbSNP
rs1303877188 1233 dbSNP
rs1339575612 1235 dbSNP
rs995872272 1236 dbSNP
rs1224095106 1239 dbSNP
rs1022938465 1244 dbSNP
rs1285113710 1250 dbSNP
rs886054172 1257 dbSNP
rs943516725 1258 dbSNP
rs1038278493 1259 dbSNP
rs566711349 1261 dbSNP
rs919654490 1262 dbSNP
rs2915966 1263 dbSNP
rs1261540922 1267 dbSNP
rs2978615 1269 dbSNP
rs573433655 1270 dbSNP
rs1271612690 1274 dbSNP
rs1199328383 1278 dbSNP
rs1257389541 1281 dbSNP
rs1214169810 1282 dbSNP
rs1316676978 1285 dbSNP
rs543880088 1288 dbSNP
rs886800436 1290 dbSNP
rs556381931 1293 dbSNP
rs1314481375 1294 dbSNP
rs1396613898 1299 dbSNP
rs1057085416 1303 dbSNP
rs1381691007 1304 dbSNP
rs1287310026 1305 dbSNP
rs1364042003 1317 dbSNP
rs1003108334 1318 dbSNP
rs1158969365 1320 dbSNP
rs1035802302 1325 dbSNP
rs72658876 1326 dbSNP
rs1186305784 1327 dbSNP
rs1423879019 1332 dbSNP
rs10415069 1333 dbSNP
rs1184378973 1335 dbSNP
rs72658877 1337 dbSNP
rs1219175449 1338 dbSNP
rs186461273 1341 dbSNP
rs1291687824 1347 dbSNP
rs967844018 1349 dbSNP
rs1293472492 1350 dbSNP
rs998968531 1350 dbSNP
rs7258146 1355 dbSNP
rs886054173 1357 dbSNP
rs932540402 1358 dbSNP
rs986757456 1365 dbSNP
rs191796971 1370 dbSNP
rs1162567206 1371 dbSNP
rs55903358 1377 dbSNP
rs563300769 1378 dbSNP
rs13344419 1386 dbSNP
rs1477299436 1387 dbSNP
rs1263372825 1391 dbSNP
rs571673106 1394 dbSNP
rs532985164 1395 dbSNP
rs1023575735 1398 dbSNP
rs766298942 1399 dbSNP
rs931426690 1402 dbSNP
rs1191100844 1403 dbSNP
rs1250670286 1406 dbSNP
rs1249699598 1407 dbSNP
rs1280319707 1407 dbSNP
rs35921663 1407 dbSNP
rs1440999316 1408 dbSNP
rs773647470 1409 dbSNP
rs1487173855 1412 dbSNP
rs1044360829 1415 dbSNP
rs1322607812 1416 dbSNP
rs1176460493 1417 dbSNP
rs1387307471 1417 dbSNP
rs1257290698 1418 dbSNP
rs72658878 1418 dbSNP
rs1464647059 1419 dbSNP
rs751672818 1419 dbSNP
rs1035869546 1420 dbSNP
rs55971831 1420 dbSNP
rs1377444970 1421 dbSNP
rs1425068315 1424 dbSNP
rs1165191772 1429 dbSNP
rs1348068399 1430 dbSNP
rs7254521 1431 dbSNP
rs1260283970 1433 dbSNP
rs1202047501 1435 dbSNP
rs1298648664 1436 dbSNP
rs1374228174 1440 dbSNP
rs1449070328 1443 dbSNP
rs1010798824 1445 dbSNP
rs1332830912 1451 dbSNP
rs190954582 1452 dbSNP
rs1046838059 1453 dbSNP
rs5742911 1454 dbSNP
rs1332734555 1456 dbSNP
rs1467916861 1465 dbSNP
rs938324505 1475 dbSNP
rs566918949 1476 dbSNP
rs375312185 1478 dbSNP
rs1362614662 1480 dbSNP
rs1013261538 1483 dbSNP
rs1042897688 1492 dbSNP
rs1240129401 1494 dbSNP
rs1440807444 1494 dbSNP
rs1181770014 1497 dbSNP
rs953729774 1504 dbSNP
rs904379725 1507 dbSNP
rs17249057 1511 dbSNP
rs1252395608 1512 dbSNP
rs555846154 1522 dbSNP
rs1031793943 1523 dbSNP
rs890539100 1532 dbSNP
rs1008876685 1538 dbSNP
rs1310813684 1539 dbSNP
rs1018036324 1541 dbSNP
rs143587805 1551 dbSNP
rs1339564747 1558 dbSNP
rs1334375934 1559 dbSNP
rs919800171 1562 dbSNP
rs973650803 1564 dbSNP
rs1310942760 1566 dbSNP
rs931380082 1567 dbSNP
rs1420853872 1573 dbSNP
rs1181899443 1574 dbSNP
rs1382631517 1574 dbSNP
rs548005398 1591 dbSNP
rs545290692 1593 dbSNP
rs17249064 1601 dbSNP
rs1238320469 1602 dbSNP
rs950921740 1606 dbSNP
rs886054174 1610 dbSNP
rs572677883 1611 dbSNP
rs1215534822 1616 dbSNP
rs1423023118 1617 dbSNP
rs983594735 1618 dbSNP
rs938645198 1620 dbSNP
rs1354999039 1621 dbSNP
rs1402296149 1629 dbSNP
rs1284234983 1631 dbSNP
rs1057078377 1647 dbSNP
rs1337888656 1651 dbSNP
rs1297979698 1670 dbSNP
rs1400994013 1671 dbSNP
rs1329342489 1675 dbSNP
rs778802644 1677 dbSNP
rs1399615433 1678 dbSNP
rs1453704614 1679 dbSNP
rs1286176511 1690 dbSNP
rs908243897 1694 dbSNP
rs892013126 1697 dbSNP
rs1163270455 1701 dbSNP
rs938446725 1704 dbSNP
rs1022190920 1706 dbSNP
rs1165014973 1707 dbSNP
rs1228052565 1710 dbSNP
rs992476656 1717 dbSNP
rs904726533 1718 dbSNP
rs915589547 1724 dbSNP
rs1192743536 1726 dbSNP
rs1488481188 1734 dbSNP
rs2738467 1744 dbSNP
rs1028044712 1745 dbSNP
rs1289988982 1748 dbSNP
rs561307544 1752 dbSNP
rs886054175 1753 dbSNP
rs1019292134 1756 dbSNP
rs961577206 1759 dbSNP
rs550542566 1763 dbSNP
rs531745927 1765 dbSNP
rs778804960 1772 dbSNP
rs972700165 1775 dbSNP
rs1235369611 1780 dbSNP
rs1325684703 1783 dbSNP
rs758370550 1785 dbSNP
rs1053381325 1786 dbSNP
rs919751976 1788 dbSNP
rs890517388 1792 dbSNP
rs886054176 1794 dbSNP
rs1017587854 1796 dbSNP
rs900543003 1797 dbSNP
rs995044372 1799 dbSNP
rs1247210396 1807 dbSNP
rs927356968 1811 dbSNP
rs1456054976 1814 dbSNP
rs182610727 1819 dbSNP
rs565257190 1824 dbSNP
rs1423094635 1826 dbSNP
rs886054177 1832 dbSNP
rs1057438076 1833 dbSNP
rs1299647076 1836 dbSNP
rs913254371 1837 dbSNP
rs1368984999 1852 dbSNP
rs1277098211 1856 dbSNP
rs1444703766 1857 dbSNP
rs886054178 1859 dbSNP
rs1332064739 1867 dbSNP
rs532600680 1868 dbSNP
rs551318860 1871 dbSNP
rs1357578385 1875 dbSNP
rs563396169 1887 dbSNP
rs570174558 1889 dbSNP
rs560271380 1890 dbSNP
rs1425853363 1891 dbSNP
rs904783005 1895 dbSNP
rs886054179 1896 dbSNP
rs1237059160 1898 dbSNP
rs1278117731 1899 dbSNP
rs1458862093 1903 dbSNP
rs1253866443 1906 dbSNP
rs1323697038 1907 dbSNP
rs1313115828 1911 dbSNP
rs779420644 1912 dbSNP
rs993011316 1913 dbSNP
rs886054180 1917 dbSNP
rs886054181 1918 dbSNP
rs1008010866 1920 dbSNP
rs1311200900 1926 dbSNP
rs527624457 1927 dbSNP
rs1377319352 1929 dbSNP
rs886054182 1932 dbSNP
rs570806765 1933 dbSNP
rs994483607 1934 dbSNP
rs533863963 1936 dbSNP
rs952648324 1940 dbSNP
rs979875703 1944 dbSNP
rs1158781903 1947 dbSNP
rs1420326940 1950 dbSNP
rs746589232 1958 dbSNP
rs1192933878 1959 dbSNP
rs1269444345 1960 dbSNP
rs1239592308 1961 dbSNP
rs8108932 1961 dbSNP
rs567179124 1962 dbSNP
rs975244851 1969 dbSNP
rs992964572 1975 dbSNP
rs1287354272 1981 dbSNP
rs925836285 1983 dbSNP
rs934576650 1984 dbSNP
rs1052943761 1985 dbSNP
rs1423347658 1988 dbSNP
rs946032559 1996 dbSNP
rs1381545519 1997 dbSNP
rs539827046 2005 dbSNP
rs549718129 2006 dbSNP
rs1359874388 2008 dbSNP
rs944805816 2009 dbSNP
rs932236221 2012 dbSNP
rs1050571534 2013 dbSNP
rs192140687 2014 dbSNP
rs900600454 2016 dbSNP
rs72658879 2017 dbSNP
rs567174080 2018 dbSNP
rs554118355 2019 dbSNP
rs1207447487 2020 dbSNP
rs1272623393 2020 dbSNP
rs1343636010 2023 dbSNP
rs1224059331 2034 dbSNP
rs1487765025 2036 dbSNP
rs1287707182 2041 dbSNP
rs1264955085 2042 dbSNP
rs886666162 2044 dbSNP
rs1351258310 2045 dbSNP
rs746880706 2045 dbSNP
rs1216610165 2046 dbSNP
rs1215543312 2049 dbSNP
rs1298529838 2053 dbSNP
rs1035178158 2054 dbSNP
rs28398082 2055 dbSNP
rs1013998032 2058 dbSNP
rs1453203726 2064 dbSNP
rs1023103008 2065 dbSNP
rs1388402980 2065 dbSNP
rs1292505823 2066 dbSNP
rs969813182 2069 dbSNP
rs1034142504 2070 dbSNP
rs545860269 2070 dbSNP
rs886054183 2070 dbSNP
rs374512158 2071 dbSNP
rs925636763 2077 dbSNP
rs955921135 2090 dbSNP
rs1179557985 2091 dbSNP
rs1382339095 2093 dbSNP
rs148054434 2112 dbSNP
rs967887118 2118 dbSNP
rs1158375667 2119 dbSNP
rs1318800359 2126 dbSNP
rs142697277 2127 dbSNP
rs1229335392 2130 dbSNP
rs184187776 2133 dbSNP
rs1386885578 2135 dbSNP
rs769309590 2137 dbSNP
rs1322141149 2138 dbSNP
rs932204930 2139 dbSNP
rs1330061813 2141 dbSNP
rs1170061974 2148 dbSNP
rs530461625 2148 dbSNP
rs912057355 2151 dbSNP
rs1377593430 2152 dbSNP
rs1200234957 2155 dbSNP
rs1455926629 2167 dbSNP
rs886054184 2174 dbSNP
rs1178022092 2175 dbSNP
rs1458435634 2175 dbSNP
rs1311010305 2178 dbSNP
rs753826430 2186 dbSNP
rs1036956819 2190 dbSNP
rs1255156293 2195 dbSNP
rs1315525771 2195 dbSNP
rs1173461249 2196 dbSNP
rs1437128950 2196 dbSNP
rs1477178403 2196 dbSNP
rs397844005 2196 dbSNP
rs3980933 2196 dbSNP
rs368041346 2197 dbSNP
rs371525227 2198 dbSNP
rs778157541 2198 dbSNP
rs1358160675 2199 dbSNP
rs146964476 2204 dbSNP
rs930744516 2204 dbSNP
rs1440373791 2205 dbSNP
rs896873275 2207 dbSNP
rs1211257792 2209 dbSNP
rs886054185 2209 dbSNP
rs1491233508 2211 dbSNP
rs1491585127 2211 dbSNP
rs73925118 2211 dbSNP
rs886054186 2211 dbSNP
rs397762834 2212 dbSNP
rs200039283 2213 dbSNP
rs1289040389 2215 dbSNP
rs80142115 2217 dbSNP
rs17249393 2219 dbSNP
rs1359242501 2221 dbSNP
rs1057153077 2227 dbSNP
rs1034193474 2231 dbSNP
rs1410287571 2234 dbSNP
rs1161479011 2249 dbSNP
rs1178227397 2251 dbSNP
rs886054187 2252 dbSNP
rs1014068352 2259 dbSNP
rs1188466932 2268 dbSNP
rs1486509831 2271 dbSNP
rs1473971795 2279 dbSNP
rs1012789318 2281 dbSNP
rs1023821990 2282 dbSNP
rs969781959 2283 dbSNP
rs1207546191 2285 dbSNP
rs775981249 2287 dbSNP
rs1465721096 2290 dbSNP
rs763224255 2296 dbSNP
rs967477623 2297 dbSNP
rs1032675131 2308 dbSNP
rs1357936896 2309 dbSNP
rs955724167 2315 dbSNP
rs1033009907 2318 dbSNP
rs72658880 2320 dbSNP
rs986139751 2320 dbSNP
rs912109652 2321 dbSNP
rs1321749513 2323 dbSNP
rs911756108 2323 dbSNP
rs944965682 2328 dbSNP
rs1391769773 2332 dbSNP
rs1167406110 2334 dbSNP
rs574560919 2347 dbSNP
rs974955474 2348 dbSNP
rs565264863 2351 dbSNP
rs930712017 2357 dbSNP
rs1218804626 2358 dbSNP
rs886054188 2366 dbSNP
rs886054189 2367 dbSNP
rs1215203964 2376 dbSNP
rs1257831337 2376 dbSNP
rs1260123022 2381 dbSNP
rs1049175551 2382 dbSNP
rs188658294 2383 dbSNP
rs886054190 2385 dbSNP
rs1364777556 2386 dbSNP
rs907874205 2390 dbSNP
rs1436333971 2391 dbSNP
rs1371841315 2397 dbSNP
rs1327938663 2398 dbSNP
rs1464264939 2401 dbSNP
rs113240958 2406 dbSNP
rs1399829240 2408 dbSNP
rs1169553095 2412 dbSNP
rs888202896 2428 dbSNP
rs936967139 2437 dbSNP
rs1061878 2439 dbSNP
rs1198316638 2445 dbSNP
rs1257052904 2455 dbSNP
rs1444499623 2463 dbSNP
rs1253098740 2468 dbSNP
rs1477629738 2468 dbSNP
rs984075081 2474 dbSNP
rs1056470933 2476 dbSNP
rs1055408843 2478 dbSNP
rs1456222441 2480 dbSNP
rs1237177851 2483 dbSNP
rs1205728017 2487 dbSNP
rs1309661507 2488 dbSNP
rs1185822547 2493 dbSNP
rs541509311 2494 dbSNP
rs1305804047 2496 dbSNP
rs1444637007 2497 dbSNP
rs866978192 2502 dbSNP
rs1368424337 2505 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uauucucagagGGGGACAUAUa 5'
                     || ||||||| 
Target 5' --------aaaCCACUGUAUAg 3'
 		1 - 14
2 
miRNA  3' uaUUCUCAGAGGG--GGACAUAUA 5'
            |||: |:|: :  |||| ||:|
Target 5' agAAGGUUUUUGUAGCCUGAAUGU 3'
 		13 - 36
Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000558518.1 | 3UTR | AAACCACUGUAUAGAAGGUUUUUGUAGCCUGAAUGUCUUACUGUGAUCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
114 hsa-miR-1185-1-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT066415 TBK1 TANK binding kinase 1 2 4
MIRT073567 NR2F2 nuclear receptor subfamily 2 group F member 2 2 2
MIRT074516 USP1 ubiquitin specific peptidase 1 2 4
MIRT080576 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 6
MIRT086539 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT086547 MOB4 MOB family member 4, phocein 2 2
MIRT088684 EML4 echinoderm microtubule associated protein like 4 2 4
MIRT090811 MBNL1 muscleblind like splicing regulator 1 2 4
MIRT095500 PURA purine rich element binding protein A 2 2
MIRT109530 KLHL15 kelch like family member 15 2 6
MIRT109807 ZFX zinc finger protein, X-linked 2 2
MIRT117888 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT120273 GSK3B glycogen synthase kinase 3 beta 2 4
MIRT149892 LDLR low density lipoprotein receptor 2 2
MIRT178475 LCOR ligand dependent nuclear receptor corepressor 2 4
MIRT193445 RORA RAR related orphan receptor A 2 2
MIRT198527 DSG2 desmoglein 2 2 2
MIRT226427 TP53INP1 tumor protein p53 inducible nuclear protein 1 2 2
MIRT227669 SET SET nuclear proto-oncogene 2 2
MIRT320405 HOXA9 homeobox A9 2 2
MIRT407774 MRPL35 mitochondrial ribosomal protein L35 2 2
MIRT439228 ZMIZ1 zinc finger MIZ-type containing 1 1 1
MIRT439312 VAT1L vesicle amine transport 1 like 1 1
MIRT439421 TMOD1 tropomodulin 1 1 1
MIRT439446 TMEM104 transmembrane protein 104 1 1
MIRT439524 STIM2 stromal interaction molecule 2 1 1
MIRT439612 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 1 1
MIRT439997 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 1
MIRT440017 PCSK1 proprotein convertase subtilisin/kexin type 1 1 1
MIRT440131 NCOA4 nuclear receptor coactivator 4 1 1
MIRT440311 LRRC1 leucine rich repeat containing 1 1 1
MIRT440475 IAPP islet amyloid polypeptide 1 1
MIRT440511 HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1 1
MIRT440617 FOXA2 forkhead box A2 1 1
MIRT440666 FBXL16 F-box and leucine rich repeat protein 16 1 1
MIRT440705 ERO1LB endoplasmic reticulum oxidoreductase 1 beta 1 1
MIRT441007 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 1 1
MIRT441018 CAND1 cullin associated and neddylation dissociated 1 1 1
MIRT441062 C1orf43 chromosome 1 open reading frame 43 1 1
MIRT441209 ARCN1 archain 1 1 1
MIRT449461 HAT1 histone acetyltransferase 1 2 2
MIRT467104 SRI sorcin 2 2
MIRT468060 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 10
MIRT468476 SESN3 sestrin 3 2 4
MIRT473533 MAX MYC associated factor X 2 2
MIRT473852 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT474711 KIF13A kinesin family member 13A 2 6
MIRT481665 ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2 2
MIRT485120 SF3B3 splicing factor 3b subunit 3 2 2
MIRT493055 MTFR1 mitochondrial fission regulator 1 2 2
MIRT504258 C1orf147 chromosome 1 open reading frame 147 2 4
MIRT504361 ARID1B AT-rich interaction domain 1B 2 4
MIRT505748 SENP1 SUMO1/sentrin specific peptidase 1 2 8
MIRT506298 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT508442 ZNF608 zinc finger protein 608 2 4
MIRT512782 COL4A3BP collagen type IV alpha 3 binding protein 2 2
MIRT520447 TSPAN2 tetraspanin 2 2 4
MIRT522133 NRBF2 nuclear receptor binding factor 2 2 6
MIRT522395 MYADM myeloid associated differentiation marker 2 4
MIRT523397 GRIK3 glutamate ionotropic receptor kainate type subunit 3 2 4
MIRT523938 E2F8 E2F transcription factor 8 2 4
MIRT524349 CREB1 cAMP responsive element binding protein 1 2 2
MIRT524711 BRMS1L breast cancer metastasis-suppressor 1 like 2 4
MIRT525134 ZNF256 zinc finger protein 256 2 2
MIRT525710 DCAF12L2 DDB1 and CUL4 associated factor 12 like 2 2 2
MIRT531264 PPIL3 peptidylprolyl isomerase like 3 2 2
MIRT538844 BTG1 BTG anti-proliferation factor 1 2 2
MIRT541366 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT542093 KCNK10 potassium two pore domain channel subfamily K member 10 2 6
MIRT543770 RBM12B RNA binding motif protein 12B 2 4
MIRT543940 NCOA7 nuclear receptor coactivator 7 2 2
MIRT545150 GABRG1 gamma-aminobutyric acid type A receptor gamma1 subunit 2 2
MIRT545842 ZNF264 zinc finger protein 264 2 4
MIRT548057 GOLGA7 golgin A7 2 2
MIRT549242 ATXN1L ataxin 1 like 2 4
MIRT551829 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 2
MIRT552484 ZNF136 zinc finger protein 136 2 2
MIRT553663 TGFBR2 transforming growth factor beta receptor 2 2 2
MIRT554988 RAB39B RAB39B, member RAS oncogene family 2 2
MIRT555760 PCTP phosphatidylcholine transfer protein 2 2
MIRT556923 IRF2BP2 interferon regulatory factor 2 binding protein 2 2 4
MIRT564991 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT566458 PGGT1B protein geranylgeranyltransferase type I subunit beta 2 2
MIRT566538 PANK3 pantothenate kinase 3 2 2
MIRT567732 DLX2 distal-less homeobox 2 2 2
MIRT570081 KANSL1L KAT8 regulatory NSL complex subunit 1 like 2 2
MIRT571735 RNF11 ring finger protein 11 2 2
MIRT573529 MDM2 MDM2 proto-oncogene 2 2
MIRT574459 RPS16 ribosomal protein S16 2 2
MIRT574992 Phka1 phosphorylase kinase alpha 1 2 3
MIRT576349 Pxdn peroxidasin 2 2
MIRT610196 CD99 CD99 molecule (Xg blood group) 2 4
MIRT612920 GPRIN3 GPRIN family member 3 2 2
MIRT615021 DUSP6 dual specificity phosphatase 6 2 2
MIRT623573 IRS1 insulin receptor substrate 1 2 2
MIRT624437 CASD1 CAS1 domain containing 1 2 2
MIRT628714 ZNF585A zinc finger protein 585A 2 2
MIRT639565 PCK1 phosphoenolpyruvate carboxykinase 1 2 4
MIRT641485 POLA2 DNA polymerase alpha 2, accessory subunit 2 2
MIRT641657 PAPOLG poly(A) polymerase gamma 2 2
MIRT642210 RUVBL2 RuvB like AAA ATPase 2 2 2
MIRT653010 STX7 syntaxin 7 2 2
MIRT656130 MSH6 mutS homolog 6 2 2
MIRT656893 KIAA2018 upstream transcription factor family member 3 2 2
MIRT660130 BRPF3 bromodomain and PHD finger containing 3 2 2
MIRT660855 AFAP1 actin filament associated protein 1 2 2
MIRT676843 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 3
MIRT681473 DIP2A disco interacting protein 2 homolog A 2 2
MIRT682253 RS1 retinoschisin 1 2 2
MIRT694296 COPB2 coatomer protein complex subunit beta 2 2 2
MIRT694401 ALDH1A3 aldehyde dehydrogenase 1 family member A3 2 2
MIRT705277 BACH1 BTB domain and CNC homolog 1 2 2
MIRT720833 C1orf52 chromosome 1 open reading frame 52 2 2
MIRT735713 SIRT1 sirtuin 1 2 0
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-1185-1 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-1185-1 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-1185-1-3p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-1185-1-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-1185-1-3p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-1185-1-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-1185-1-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-1185-1-3p Palbociclib 5330286 NSC758247 approved resistant cell line (T47D)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-1185-1-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-1185-1-3p Prednisone/Azathioprine/Methotrexate/Cyclophosphamide/Mycophenolate mofetil sensitive tissue (myasthenia gravis)
hsa-miR-1185-1-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-1185-1-3p Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-1185-1-3p Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-1185-1-3p Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-1185-1-3p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-1185-1-3p Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-1185-1-3p Gemcitabine 60750 NSC613327 approved resistant cell line (MDA-231)
hsa-miR-1185-1-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-1185-1-3p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-1185-1-3p Cisplatin 5460033 NSC119875 approved resistant cell line (TOV-112D)

Error report submission