miRTarBase - #MIRT153789


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pre-miRNA Information
pre-miRNA hsa-mir-4731   
Genomic Coordinates chr17: 15251627 - 15251696
Description Homo sapiens miR-4731 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4731-5p
Sequence 10| UGCUGGGGGCCACAUGAGUGUG |31
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1295173963 9 dbSNP
rs1227560397 15 dbSNP
rs972231157 18 dbSNP
Putative Targets

Gene Information
Gene Symbol NCOA3   
Synonyms ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP
Description nuclear receptor coactivator 3
Transcript NM_001174087   
Other Transcripts NM_001174088 , NM_006534 , NM_181659   
Expression
Putative miRNA Targets on NCOA3
3'UTR of NCOA3
(miRNA target sites are highlighted)		 
>NCOA3|NM_001174087|3'UTR
   1 CATCTCTGCACCAGGACCTCTTAAGGAAACCACTGTACAAATGACACTGCACTAGGATTATTGGGAAGGAATCATTGTTC
  81 CAGGCATCCATCTTGGAAGAAAGGACCAGCTTTGAGCTCCATCAAGGGTATTTTAAGTGATGTCATTTGAGCAGGACTGG
 161 ATTTTAAGCCGAAGGGCAATATCTACGTGTTTTTCCCCCCTCCTTCTGCTGTGTATCATGGTGTTCAAAACAGAAATGTT
 241 TTTTGGCATTCCACCTCCTAGGGATATAATTCTGGAGACATGGAGTGTTACTGATCATAAAACTTTTGTGTCACTTTTTT
 321 CTGCCTTGCTAGCCAAAATCTCTTAAATACACGTAGGTGGGCCAGAGAACATTGGAAGAATCAAGAGAGATTAGAATATC
 401 TGGTTTCTCTAGTTGCAGTATTGGACAAAGAGCATAGTCCCAGCCTTCAGGTGTAGTAGTTCTGTGTTGACCCTTTGTCC
 481 AGTGGAATTGGTGATTCTGAATTGTCCTTTACTAATGGTGTTGAGTTGCTCTGTCCCTATTATTTGCCCTAGGCTTTCTC
 561 CTAATGAAGGTTTTCATTTGCCATTCATGTCCTGTAATACTTCACCTCCAGGAACTGTCATGGATGTCCAAATGGCTTTG
 641 CAGAAAGGAAATGAGATGACAGTATTTAATCGCAGCAGTAGCAAACTTTTCACATGCTAATGTGCAGCTGAGTGCACTTT
 721 ATTTAAAAAGAATGGATAAATGCAATATTCTTGAGGTCTTGAGGGAATAGTGAAACACATTCCTGGTTTTTGCCTACACT
 801 TACGTGTTAGACAAGAACTATGATTTTTTTTTTTAAAGTACTGGTGTCACCCTTTGCCTATATGGTAGAGCAATAATGCT
 881 TTTTAAAAATAAACTTCTGAAAACCCAAGGCCAGGTACTGCATTCTGAATCAGAATCTCGCAGTGTTTCTGTGAATAGAT
 961 TTTTTTGTAAATATGACCTTTAAGATATTGTATTATGTAAAATATGTATATACCTTTTTTTGTAGGTCACAACAACTCAT
1041 TTTTACAGAGTTTGTGAAGCTAAATATTTAACATTGTTGATTTCAGTAAGCTGTGTGGTGAGGCTACCAGTGGAAGAGAC
1121 ATCCCTTGACTTTTGTGGCCTGGGGGAGGGGTAGTGCTCCACAGCTTTTCCTTCCCCACCCCCCAGCCTTAGATGCCTCG
1201 CTCTTTTCAATCTCTTAATCTAAATGCTTTTTAAAGAGATTATTTGTTTAGATGTAGGCATTTTAATTTTTTAAAAATTC
1281 CTCTACCAGAACTAAGCACTTTGTTAATTTGGGGGGAAAGAATAGATATGGGGAAATAAACTTAAAAAAAAATCAGGAAT
1361 TTAAAAAAACGAGCAATTTGAAGAGAATCTTTTGGATTTTAAGCAGTCCGAAATAATAGCAATTCATGGGCTGTGTGTGT
1441 GTGTGTATGTGTGTGTGTGTGTGTGTATGTTTAATTATGTTACCTTTTCATCCCCTTTAGGAGCGTTTTCAGATTTTGGT
1521 TGCTAAGACCTGAATCCCATATTGAGATCTCGAGTAGAATCCTTGGTGTGGTTTCTGGTGTCTGCTCAGCTGTCCCCTCA
1601 TTCTACTAATGTGATGCTTTCATTATGTCCCTGTGGATTAGAATAGTGTCAGTTATTTCTTAAGTAACTCAGTACCCAGA
1681 ACAGCCAGTTTTACTGTGATTCAGAGCCACAGTCTAACTGAGCACCTTTTAAACCCCTCCCTCTTCTGCCCCCTACCACT
1761 TTTCTGCTGTTGCCTCTCTTTGACACCTGTTTTAGTCAGTTGGGAGGAAGGGAAAAATCAAGTTTAATTCCCTTTATCTG
1841 GGTTAATTCATTTGGTTCAAATAGTTGACGGAATTGGGTTTCTGAATGTCTGTGAATTTCAGAGGTCTCTGCTAGCCTTG
1921 GTATCATTTTCTAGCAATAACTGAGAGCCAGTTAATTTTAAGAATTTCACACATTTAGCCAATCTTTCTAGATGTCTCTG
2001 AAGGTAAGATCATTTAATATCTTTGATATGCTTACGAGTAAGTGAATCCTGATTATTTCCAGACCCACCACCAGAGTGGA
2081 TCTTATTTTCAAAGCAGTATAGACAATTATGAGTTTGCCCTCTTTCCCCTACCAAGTTCAAAATATATCTAAGAAAGATT
2161 GTAAATCCGAAAACTTCCATTGTAGTGGCCTGTGCTTTTCAGATAGTATACTCTCCTGTTTGGAGACAGAGGAAGAACCA
2241 GGTCAGTCTGTCTCTTTTTCAGCTCAATTGTATCTGACCCTTCTTTAAGTTATGTGTGTGGGGAGAAATAGAATGGTGCT
2321 CTTATCTTTCTTGACTTTAAAAAAATTATTAAAAACAAAAAAAAAATAAATTTTTTTGCAATCCTTTCCTCAGACCTGGC
2401 TCCAGGCTAACTGGAAGGCAGCACTCCCTTTTTTATATAGTAGAAAAATGAAGTTTATTATAAGTTTTTATATTTTCTAC
2481 TTGTTCATTTGGTGCAAACTCAAGATTTCTTTTAATAGGTGCAGTCTTTGAGATAATTTGTTTTTACCTGTATTGCCCTT
2561 TATCTTTTTTAGGTAATTCTTTGTACTCCTGCTGTCTACCTCTCCTCACACCCCAGCACCCCCCATTTTTTCAAACCTTG
2641 GTATCTGTTGGGTGAACAGTATAATCTTTTCATCTGCTTTTAGAATGTGGGATATTTCCAGTACCTACTTTTTTTTTTTT
2721 TTTTTGCTGAATCCAAAGATATATAAATAAAATATATATATTTTATAAAGATCAGAATGATATAAAGGAGATACATGTTT
2801 CTTCCTTTAAAAAATAAACGGAAGTTACATTGTTAATGTTCATATTATGATGCCACTTTTCTAAACTGCATCTGGATTGA
2881 AAGGTGTAAATATCAATAACAGTGCTACTTAGTTATCAGTATTTAATATCTGAGGTGAGTTGGGGGTATCTATATTAGGG
2961 GTAGGGTATTACAGAAGATAATTGGCTTGATGTCCTAGAAGTTCTTTGATCCAGAGGTGGGTGCAGCTGAAAGTAAACAG
3041 AATGGATTGCCAGTTACATGTATGCCTGCCCAGTTCCCTTTTTATTTGCAGAAGCTGTGAGTTTTGTTCACAATTAGGTT
3121 CCTAGGAGCAAAACCTCAAGGATTGATTTATTGTTTTCAACTCCAAGGCACACTGTTAATAAACGAGCAGGGTGTTTTCT
3201 CTCTTCCTTTCTAATATATGGAGTTTCGAAGAATAAAATATGAGAGCAATATTTAAATTCTCAGGAATTGACTTATACTC
3281 TTGAGAATGAATTCAGTTTCAATCAAGTTTACATTATGTTGCTTAAAAAAATAGAAATTATTCTTTATCTTGCAAAGAAT
3361 TGAAACCACATGAAATGACTTATGGGGGATGGTGAGCTGTGACTGCTTTGCTGACCATTTTGGATGTCATTGTAAATAAA
3441 GGTTTCTATTTAAAATTGGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gugugaguacaccGGGGGUCGu 5'
                       |||||||| 
Target 5' tttccttccccacCCCCCAGCc 3'
 1167 - 1188 145.00 -17.50
2 
miRNA  3' guguGAGUACACCG-GGGGUCGu 5'
              |||   |  | ||||||| 
Target 5' ctacCTCTCCTCACACCCCAGCa 3'
 2596 - 2618 142.00 -19.36
3 
miRNA  3' gugugaguacaccgGGGGUCGu 5'
                        :|||||| 
Target 5' gacaaagagcatagTCCCAGCc 3'
 424 - 445 124.00 -12.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30154093 7 COSMIC
COSN30506284 42 COSMIC
COSN26986111 69 COSMIC
COSN30182759 82 COSMIC
COSN30163171 88 COSMIC
COSN30514214 144 COSMIC
COSN26986110 150 COSMIC
COSN21368554 153 COSMIC
COSN26439846 157 COSMIC
COSN13866098 171 COSMIC
COSN30184031 173 COSMIC
COSN30184079 175 COSMIC
COSN20116506 183 COSMIC
COSN13866100 195 COSMIC
COSN18742969 195 COSMIC
COSN13866101 196 COSMIC
COSN18716767 246 COSMIC
COSN10016884 486 COSMIC
COSN24716719 495 COSMIC
COSN31481137 762 COSMIC
COSN5134330 804 COSMIC
COSN30173914 836 COSMIC
COSN17708369 973 COSMIC
COSN26576287 1173 COSMIC
COSN31550190 1184 COSMIC
COSN16850504 1205 COSMIC
COSN30013794 1228 COSMIC
COSN31520099 1237 COSMIC
COSN31584973 1261 COSMIC
COSN1874296 1415 COSMIC
COSN1874298 1424 COSMIC
COSN27982276 1446 COSMIC
COSN15661008 1448 COSMIC
COSN20116507 1467 COSMIC
COSN27346940 1490 COSMIC
COSN1249728 1717 COSMIC
COSN17846642 1944 COSMIC
COSN15660835 1980 COSMIC
COSN31514909 2037 COSMIC
COSN4780692 2120 COSMIC
COSN31541352 2207 COSMIC
COSN26566538 2247 COSMIC
COSN31572227 2275 COSMIC
COSN31523422 2318 COSMIC
COSN31532982 2367 COSMIC
COSN31595265 2413 COSMIC
COSN20093776 2500 COSMIC
COSN31518292 2638 COSMIC
COSN26648905 2684 COSMIC
COSN26551584 2688 COSMIC
COSN27320729 2725 COSMIC
COSN20116510 2726 COSMIC
COSN20116511 2726 COSMIC
COSN31513863 2739 COSMIC
COSN8000142 2949 COSMIC
COSN27176470 3040 COSMIC
COSN20116513 3134 COSMIC
COSN31548543 3238 COSMIC
COSN30169507 3269 COSMIC
COSN31607500 3327 COSMIC
COSN31609680 3358 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1193277936 4 dbSNP
rs545763445 14 dbSNP
rs372774941 16 dbSNP
rs779126997 17 dbSNP
rs1382279568 24 dbSNP
rs1288982007 29 dbSNP
rs1420362270 30 dbSNP
rs1163223942 32 dbSNP
rs72646207 41 dbSNP
rs754765634 44 dbSNP
rs1475776467 46 dbSNP
rs781170022 50 dbSNP
rs748096633 51 dbSNP
rs72646208 62 dbSNP
rs1186437620 67 dbSNP
rs1482927503 75 dbSNP
rs1251993528 77 dbSNP
rs1206825435 104 dbSNP
rs942247115 111 dbSNP
rs1036651258 113 dbSNP
rs1257714900 128 dbSNP
rs897994321 129 dbSNP
rs1468481628 131 dbSNP
rs1355916391 147 dbSNP
rs1302009745 152 dbSNP
rs1394225286 153 dbSNP
rs1377761287 157 dbSNP
rs1298274273 166 dbSNP
rs773241577 170 dbSNP
rs575463833 171 dbSNP
rs915248108 172 dbSNP
rs889219876 175 dbSNP
rs1007949716 177 dbSNP
rs1163239296 178 dbSNP
rs3092324 179 dbSNP
rs397839606 179 dbSNP
rs1339188286 180 dbSNP
rs978746126 180 dbSNP
rs3092417 186 dbSNP
rs6094766 187 dbSNP
rs1055319558 190 dbSNP
rs894869050 191 dbSNP
rs930389147 194 dbSNP
rs1009429764 195 dbSNP
rs572909502 196 dbSNP
rs886105835 197 dbSNP
rs1004588244 200 dbSNP
rs541654693 201 dbSNP
rs1441213796 204 dbSNP
rs1292121954 206 dbSNP
rs1397075046 206 dbSNP
rs1486407839 211 dbSNP
rs981925551 216 dbSNP
rs77034911 245 dbSNP
rs189567471 254 dbSNP
rs1379772811 255 dbSNP
rs984306949 260 dbSNP
rs576879510 264 dbSNP
rs143376484 267 dbSNP
rs1271193301 271 dbSNP
rs989525593 273 dbSNP
rs1261178003 275 dbSNP
rs1431613215 285 dbSNP
rs1350808694 287 dbSNP
rs181330239 288 dbSNP
rs1234441789 291 dbSNP
rs961073420 292 dbSNP
rs1372678699 293 dbSNP
rs1298826363 295 dbSNP
rs1386552997 297 dbSNP
rs1386154599 300 dbSNP
rs1291080250 302 dbSNP
rs756904105 305 dbSNP
rs1418442698 306 dbSNP
rs1292345133 307 dbSNP
rs374835226 313 dbSNP
rs1455688174 315 dbSNP
rs919516314 316 dbSNP
rs1198436724 317 dbSNP
rs1376116155 317 dbSNP
rs933445793 324 dbSNP
rs978145414 329 dbSNP
rs1051955117 335 dbSNP
rs1218638218 337 dbSNP
rs1487252994 340 dbSNP
rs1285267452 342 dbSNP
rs1210977672 349 dbSNP
rs1346585257 352 dbSNP
rs147170444 353 dbSNP
rs961001788 354 dbSNP
rs548567147 357 dbSNP
rs1298219774 363 dbSNP
rs139500644 368 dbSNP
rs1054312038 373 dbSNP
rs1340418546 376 dbSNP
rs1436596473 383 dbSNP
rs930839196 383 dbSNP
rs893804066 385 dbSNP
rs1009532830 389 dbSNP
rs1400161625 409 dbSNP
rs548508082 410 dbSNP
rs1359806947 425 dbSNP
rs1048836015 427 dbSNP
rs1405531991 429 dbSNP
rs1375048318 434 dbSNP
rs749939730 437 dbSNP
rs1476754840 452 dbSNP
rs1262375887 454 dbSNP
rs1188592116 460 dbSNP
rs1343123979 464 dbSNP
rs1443578353 465 dbSNP
rs560394083 474 dbSNP
rs72646209 485 dbSNP
rs879917843 486 dbSNP
rs1307272511 487 dbSNP
rs1199478765 495 dbSNP
rs1318424830 506 dbSNP
rs1339635509 506 dbSNP
rs1259636264 508 dbSNP
rs779718716 509 dbSNP
rs940334366 513 dbSNP
rs1241610026 515 dbSNP
rs866447867 517 dbSNP
rs1040056072 518 dbSNP
rs552306036 520 dbSNP
rs1294369548 527 dbSNP
rs1417195361 530 dbSNP
rs1338723239 533 dbSNP
rs1353580628 538 dbSNP
rs1033505507 547 dbSNP
rs115501901 548 dbSNP
rs1005299988 549 dbSNP
rs1271077549 554 dbSNP
rs1398898459 565 dbSNP
rs1487553630 571 dbSNP
rs1017098504 572 dbSNP
rs1463817566 581 dbSNP
rs1422663596 587 dbSNP
rs45610642 590 dbSNP
rs892968721 595 dbSNP
rs1421163940 596 dbSNP
rs1186186808 598 dbSNP
rs1437974642 606 dbSNP
rs1176517126 608 dbSNP
rs1011397103 611 dbSNP
rs769064038 622 dbSNP
rs1425171070 630 dbSNP
rs1165412600 650 dbSNP
rs1274220797 651 dbSNP
rs972404146 672 dbSNP
rs919485341 673 dbSNP
rs557576342 675 dbSNP
rs1456968661 677 dbSNP
rs1239840072 680 dbSNP
rs1379232110 680 dbSNP
rs781595793 701 dbSNP
rs550293555 705 dbSNP
rs1446364366 710 dbSNP
rs1399217998 720 dbSNP
rs1326309672 721 dbSNP
rs1406918970 723 dbSNP
rs1035036337 731 dbSNP
rs954923385 735 dbSNP
rs1444177379 736 dbSNP
rs113935223 738 dbSNP
rs1381656185 739 dbSNP
rs961208034 740 dbSNP
rs757628463 743 dbSNP
rs1438667251 744 dbSNP
rs1307482558 746 dbSNP
rs1450298477 747 dbSNP
rs991069450 753 dbSNP
rs988156270 754 dbSNP
rs910710310 766 dbSNP
rs1247276367 780 dbSNP
rs748498017 781 dbSNP
rs1307207578 796 dbSNP
rs1320510570 802 dbSNP
rs1371964086 804 dbSNP
rs569112996 805 dbSNP
rs536435823 808 dbSNP
rs185024445 816 dbSNP
rs573073843 819 dbSNP
rs1322768735 824 dbSNP
rs1347905913 824 dbSNP
rs984982259 824 dbSNP
rs915341513 829 dbSNP
rs1252012997 836 dbSNP
rs1438608962 844 dbSNP
rs907596234 845 dbSNP
rs1481721352 851 dbSNP
rs945357995 855 dbSNP
rs1246525394 859 dbSNP
rs1042353320 861 dbSNP
rs940462763 864 dbSNP
rs1489546459 865 dbSNP
rs35259021 867 dbSNP
rs770047112 868 dbSNP
rs1392114693 871 dbSNP
rs1431533159 872 dbSNP
rs1166711223 873 dbSNP
rs1217720784 875 dbSNP
rs1365164547 885 dbSNP
rs1274005388 904 dbSNP
rs552539526 905 dbSNP
rs1445027461 907 dbSNP
rs1003454568 912 dbSNP
rs1342283630 913 dbSNP
rs773481223 915 dbSNP
rs1411521581 916 dbSNP
rs570651593 917 dbSNP
rs573895935 919 dbSNP
rs369028562 936 dbSNP
rs558275694 940 dbSNP
rs763174545 941 dbSNP
rs144538511 950 dbSNP
rs544019069 956 dbSNP
rs1011346280 957 dbSNP
rs994415873 959 dbSNP
rs1041565841 960 dbSNP
rs1486016748 978 dbSNP
rs542919435 989 dbSNP
rs1218994612 991 dbSNP
rs1319752132 997 dbSNP
rs1276148729 999 dbSNP
rs999620425 1004 dbSNP
rs149248173 1007 dbSNP
rs1304061125 1009 dbSNP
rs993941943 1010 dbSNP
rs1029317555 1012 dbSNP
rs1445229333 1013 dbSNP
rs1358214168 1014 dbSNP
rs551088645 1015 dbSNP
rs955056863 1015 dbSNP
rs1286379510 1023 dbSNP
rs1377587872 1024 dbSNP
rs1228293001 1028 dbSNP
rs1296336158 1029 dbSNP
rs371819589 1033 dbSNP
rs1170529861 1047 dbSNP
rs960690091 1070 dbSNP
rs1416640472 1075 dbSNP
rs148491872 1090 dbSNP
rs542043111 1093 dbSNP
rs1482997772 1096 dbSNP
rs1233607733 1099 dbSNP
rs1200759767 1103 dbSNP
rs117360582 1107 dbSNP
rs1255947522 1110 dbSNP
rs1217840562 1114 dbSNP
rs990075664 1117 dbSNP
rs1801981 1138 dbSNP
rs1026254751 1148 dbSNP
rs1023877487 1152 dbSNP
rs888636028 1153 dbSNP
rs915436443 1173 dbSNP
rs945453042 1174 dbSNP
rs373321636 1180 dbSNP
rs546390148 1181 dbSNP
rs984926360 1182 dbSNP
rs1015099472 1183 dbSNP
rs1482865222 1184 dbSNP
rs1458796804 1185 dbSNP
rs72646210 1186 dbSNP
rs760641688 1189 dbSNP
rs895067448 1195 dbSNP
rs1420952096 1198 dbSNP
rs546430844 1200 dbSNP
rs941178368 1201 dbSNP
rs1237850680 1204 dbSNP
rs1197779328 1215 dbSNP
rs1267083161 1216 dbSNP
rs1038191981 1220 dbSNP
rs11699879 1223 dbSNP
rs1429532744 1233 dbSNP
rs993907580 1237 dbSNP
rs985782640 1240 dbSNP
rs1336521860 1243 dbSNP
rs780230593 1251 dbSNP
rs6125065 1254 dbSNP
rs1387644026 1267 dbSNP
rs1393331448 1268 dbSNP
rs550331893 1273 dbSNP
rs1289974351 1276 dbSNP
rs568544302 1286 dbSNP
rs146502858 1288 dbSNP
rs1343009795 1295 dbSNP
rs1041903432 1297 dbSNP
rs1418016987 1298 dbSNP
rs1017833056 1310 dbSNP
rs1379906259 1310 dbSNP
rs1199867717 1312 dbSNP
rs1216860862 1313 dbSNP
rs1277702205 1319 dbSNP
rs965315107 1322 dbSNP
rs903014743 1324 dbSNP
rs989721919 1330 dbSNP
rs1490156639 1335 dbSNP
rs1022414217 1336 dbSNP
rs1218147533 1337 dbSNP
rs1276187300 1337 dbSNP
rs966888505 1343 dbSNP
rs1056541396 1344 dbSNP
rs202154300 1344 dbSNP
rs1333138477 1345 dbSNP
rs978108178 1348 dbSNP
rs77268998 1353 dbSNP
rs928061466 1354 dbSNP
rs939339322 1363 dbSNP
rs1311401897 1364 dbSNP
rs1398165521 1368 dbSNP
rs1359987312 1370 dbSNP
rs72646211 1371 dbSNP
rs1015629989 1372 dbSNP
rs1173687330 1380 dbSNP
rs1480020184 1384 dbSNP
rs1487298778 1386 dbSNP
rs1195754427 1388 dbSNP
rs566617812 1402 dbSNP
rs941262648 1410 dbSNP
rs1200586625 1413 dbSNP
rs1346650135 1417 dbSNP
rs1038327388 1419 dbSNP
rs1269025245 1423 dbSNP
rs896986398 1425 dbSNP
rs11699902 1427 dbSNP
rs1398730417 1429 dbSNP
rs1187638177 1432 dbSNP
rs1372475120 1432 dbSNP
rs1400318871 1432 dbSNP
rs1424105917 1432 dbSNP
rs1443703430 1432 dbSNP
rs1476785961 1432 dbSNP
rs372177830 1432 dbSNP
rs914242484 1432 dbSNP
rs947094058 1432 dbSNP
rs953150679 1432 dbSNP
rs985726703 1432 dbSNP
rs1423421623 1433 dbSNP
rs1202645091 1434 dbSNP
rs1260421480 1434 dbSNP
rs1458464982 1434 dbSNP
rs1217239831 1436 dbSNP
rs1414259187 1438 dbSNP
rs1160364507 1440 dbSNP
rs1050796390 1442 dbSNP
rs924553242 1444 dbSNP
rs938511926 1444 dbSNP
rs1362982598 1445 dbSNP
rs1057380172 1446 dbSNP
rs1447820832 1446 dbSNP
rs6094767 1446 dbSNP
rs11473242 1448 dbSNP
rs144164627 1448 dbSNP
rs6090710 1448 dbSNP
rs769156345 1448 dbSNP
rs775674695 1448 dbSNP
rs896545709 1448 dbSNP
rs1182548533 1450 dbSNP
rs948124053 1454 dbSNP
rs1045046167 1466 dbSNP
rs371110073 1468 dbSNP
rs1245348896 1494 dbSNP
rs1398743965 1502 dbSNP
rs1006665803 1505 dbSNP
rs765141394 1506 dbSNP
rs575492858 1510 dbSNP
rs1273301351 1513 dbSNP
rs181794078 1514 dbSNP
rs1379393021 1519 dbSNP
rs868681788 1524 dbSNP
rs72646212 1527 dbSNP
rs997670486 1532 dbSNP
rs750033522 1537 dbSNP
rs1030469862 1541 dbSNP
rs1022506838 1552 dbSNP
rs191666426 1553 dbSNP
rs539104635 1557 dbSNP
rs1291806241 1569 dbSNP
rs1381714938 1573 dbSNP
rs1490700608 1582 dbSNP
rs1469911239 1584 dbSNP
rs537428355 1585 dbSNP
rs1247675604 1590 dbSNP
rs1035086461 1606 dbSNP
rs1201523556 1608 dbSNP
rs961055304 1609 dbSNP
rs990948272 1613 dbSNP
rs555715361 1622 dbSNP
rs1291777041 1623 dbSNP
rs557748651 1637 dbSNP
rs1245758185 1644 dbSNP
rs977516612 1650 dbSNP
rs1284071541 1651 dbSNP
rs916561162 1661 dbSNP
rs1223460893 1663 dbSNP
rs772734287 1665 dbSNP
rs962741746 1669 dbSNP
rs1275199521 1671 dbSNP
rs1470337007 1673 dbSNP
rs1178110372 1676 dbSNP
rs973944500 1680 dbSNP
rs918513463 1683 dbSNP
rs992644235 1683 dbSNP
rs915748401 1690 dbSNP
rs1382591343 1691 dbSNP
rs1418359888 1692 dbSNP
rs929765692 1692 dbSNP
rs1045164314 1695 dbSNP
rs1050899616 1699 dbSNP
rs1268730872 1700 dbSNP
rs942022355 1702 dbSNP
rs1366197029 1724 dbSNP
rs1489289579 1726 dbSNP
rs1261157256 1740 dbSNP
rs1215220885 1753 dbSNP
rs1407146546 1754 dbSNP
rs1321729910 1756 dbSNP
rs1321151517 1761 dbSNP
rs1330715705 1768 dbSNP
rs1282509502 1777 dbSNP
rs747964542 1794 dbSNP
rs1342344111 1798 dbSNP
rs1443256849 1799 dbSNP
rs865784783 1801 dbSNP
rs1359369566 1811 dbSNP
rs942438936 1815 dbSNP
rs998178997 1818 dbSNP
rs1039497950 1825 dbSNP
rs1171953899 1825 dbSNP
rs1479078352 1839 dbSNP
rs1422161638 1841 dbSNP
rs1052007232 1856 dbSNP
rs892754967 1857 dbSNP
rs574211941 1861 dbSNP
rs1208318710 1869 dbSNP
rs183437441 1870 dbSNP
rs541484234 1871 dbSNP
rs554077156 1873 dbSNP
rs187155333 1875 dbSNP
rs755476740 1879 dbSNP
rs1438010684 1881 dbSNP
rs772800423 1887 dbSNP
rs6094768 1890 dbSNP
rs1213418971 1891 dbSNP
rs1031763929 1896 dbSNP
rs1285551742 1908 dbSNP
rs1450042004 1910 dbSNP
rs959942004 1912 dbSNP
rs1178481315 1917 dbSNP
rs960938305 1940 dbSNP
rs1353259009 1943 dbSNP
rs1170363580 1949 dbSNP
rs796834693 1952 dbSNP
rs1416074632 1972 dbSNP
rs1181873240 1976 dbSNP
rs1161500038 1978 dbSNP
rs1444202891 1979 dbSNP
rs72646213 1983 dbSNP
rs1410697952 1984 dbSNP
rs1333631217 1988 dbSNP
rs1023720249 1994 dbSNP
rs983977189 2005 dbSNP
rs377697437 2010 dbSNP
rs962666812 2013 dbSNP
rs974081697 2018 dbSNP
rs1321747417 2019 dbSNP
rs942123636 2025 dbSNP
rs918616364 2031 dbSNP
rs1309609079 2032 dbSNP
rs371320520 2036 dbSNP
rs919248540 2054 dbSNP
rs531636287 2061 dbSNP
rs1458843259 2064 dbSNP
rs2664536 2070 dbSNP
rs1424159617 2071 dbSNP
rs942551961 2075 dbSNP
rs562025450 2086 dbSNP
rs1051951666 2087 dbSNP
rs529414116 2088 dbSNP
rs144185862 2097 dbSNP
rs1457085186 2107 dbSNP
rs1488751203 2111 dbSNP
rs1248455782 2117 dbSNP
rs1219607784 2118 dbSNP
rs1007656654 2129 dbSNP
rs1043216868 2130 dbSNP
rs1241897652 2133 dbSNP
rs914341346 2140 dbSNP
rs1444595285 2147 dbSNP
rs868787472 2152 dbSNP
rs1306693206 2156 dbSNP
rs947031719 2157 dbSNP
rs1387775765 2160 dbSNP
rs563905180 2169 dbSNP
rs1447774877 2170 dbSNP
rs3746480 2170 dbSNP
rs1404338462 2179 dbSNP
rs1041345196 2181 dbSNP
rs778114954 2182 dbSNP
rs999724442 2188 dbSNP
rs566594346 2189 dbSNP
rs1056756261 2200 dbSNP
rs896607477 2203 dbSNP
rs1363483692 2212 dbSNP
rs1012424554 2214 dbSNP
rs527468366 2215 dbSNP
rs898599465 2216 dbSNP
rs1431280106 2228 dbSNP
rs1433619712 2228 dbSNP
rs552218307 2229 dbSNP
rs1490028691 2232 dbSNP
rs14189 2234 dbSNP
rs895466180 2240 dbSNP
rs12273 2242 dbSNP
rs1022871730 2255 dbSNP
rs987083001 2255 dbSNP
rs1314312724 2256 dbSNP
rs1019537678 2268 dbSNP
rs1404117102 2271 dbSNP
rs964192221 2273 dbSNP
rs770906149 2275 dbSNP
rs1300082428 2279 dbSNP
rs1384513972 2285 dbSNP
rs1333438341 2286 dbSNP
rs1431186559 2291 dbSNP
rs975292230 2291 dbSNP
rs1174055572 2293 dbSNP
rs1480049457 2309 dbSNP
rs1401289433 2310 dbSNP
rs1017187874 2314 dbSNP
rs1426231727 2318 dbSNP
rs963456262 2320 dbSNP
rs972550136 2322 dbSNP
rs569753342 2323 dbSNP
rs1316883010 2324 dbSNP
rs914430891 2330 dbSNP
rs1256905246 2336 dbSNP
rs1347596286 2339 dbSNP
rs555750290 2345 dbSNP
rs1256060668 2346 dbSNP
rs1225263610 2348 dbSNP
rs977172767 2350 dbSNP
rs1313643667 2351 dbSNP
rs1397980771 2357 dbSNP
rs1404231493 2357 dbSNP
rs1469153188 2357 dbSNP
rs72646214 2357 dbSNP
rs910774182 2357 dbSNP
rs943629379 2361 dbSNP
rs1195897880 2365 dbSNP
rs1043165799 2367 dbSNP
rs1372024819 2368 dbSNP
rs904689597 2368 dbSNP
rs924275737 2370 dbSNP
rs1261165594 2371 dbSNP
rs938363778 2371 dbSNP
rs1240960388 2377 dbSNP
rs1183356885 2382 dbSNP
rs1053268805 2385 dbSNP
rs1275645576 2391 dbSNP
rs533048404 2392 dbSNP
rs774386129 2398 dbSNP
rs563500321 2409 dbSNP
rs896747286 2420 dbSNP
rs948195702 2423 dbSNP
rs2179591 2424 dbSNP
rs536607011 2426 dbSNP
rs11547289 2428 dbSNP
rs1377402668 2434 dbSNP
rs1421479414 2436 dbSNP
rs1408119960 2438 dbSNP
rs776375537 2450 dbSNP
rs1016885696 2454 dbSNP
rs1426073947 2454 dbSNP
rs1382948251 2461 dbSNP
rs572585213 2461 dbSNP
rs1234936040 2462 dbSNP
rs1180153506 2464 dbSNP
rs1339301971 2469 dbSNP
rs540001036 2470 dbSNP
rs151069803 2471 dbSNP
rs887075009 2472 dbSNP
rs1357374339 2475 dbSNP
rs774931456 2480 dbSNP
rs1329061205 2484 dbSNP
rs186687440 2489 dbSNP
rs1019928067 2493 dbSNP
rs963977525 2500 dbSNP
rs954804398 2504 dbSNP
rs1439836220 2509 dbSNP
rs1335082838 2510 dbSNP
rs975763553 2514 dbSNP
rs987396849 2517 dbSNP
rs1363206600 2520 dbSNP
rs1255814047 2521 dbSNP
rs910553419 2525 dbSNP
rs775936812 2546 dbSNP
rs1419892023 2548 dbSNP
rs943410137 2551 dbSNP
rs761819268 2555 dbSNP
rs1469956970 2558 dbSNP
rs979418762 2558 dbSNP
rs926256910 2561 dbSNP
rs1021404071 2562 dbSNP
rs1202265896 2565 dbSNP
rs1489865567 2565 dbSNP
rs140978561 2573 dbSNP
rs968560162 2574 dbSNP
rs977099015 2579 dbSNP
rs1448954114 2589 dbSNP
rs924372228 2594 dbSNP
rs1283906895 2597 dbSNP
rs1221800932 2599 dbSNP
rs1349697172 2600 dbSNP
rs1283807881 2601 dbSNP
rs938317718 2608 dbSNP
rs934808667 2613 dbSNP
rs191502116 2614 dbSNP
rs1457095526 2618 dbSNP
rs200283719 2619 dbSNP
rs1315789698 2620 dbSNP
rs1269724581 2621 dbSNP
rs1403383307 2626 dbSNP
rs915584545 2626 dbSNP
rs1431706949 2627 dbSNP
rs1429286501 2630 dbSNP
rs542386106 2639 dbSNP
rs765088204 2640 dbSNP
rs1421383767 2645 dbSNP
rs1156790289 2652 dbSNP
rs1359274423 2653 dbSNP
rs1457963769 2657 dbSNP
rs1294834467 2658 dbSNP
rs1388096406 2659 dbSNP
rs898625586 2662 dbSNP
rs1005251166 2665 dbSNP
rs762495908 2667 dbSNP
rs1300960464 2670 dbSNP
rs1214574157 2674 dbSNP
rs574077498 2677 dbSNP
rs1363491007 2687 dbSNP
rs1038674047 2703 dbSNP
rs1383123427 2705 dbSNP
rs897086940 2705 dbSNP
rs978053774 2708 dbSNP
rs1185138323 2709 dbSNP
rs1320859949 2709 dbSNP
rs1459815944 2709 dbSNP
rs1468622969 2709 dbSNP
rs200394945 2709 dbSNP
rs377097381 2709 dbSNP
rs57501886 2709 dbSNP
rs878969991 2709 dbSNP
rs1242869620 2710 dbSNP
rs1307708774 2712 dbSNP
rs1353696880 2717 dbSNP
rs1262388021 2725 dbSNP
rs1205161811 2726 dbSNP
rs1222373012 2727 dbSNP
rs1267340431 2729 dbSNP
rs1487602707 2730 dbSNP
rs1213549765 2732 dbSNP
rs1209489155 2734 dbSNP
rs1238500874 2736 dbSNP
rs1316735823 2739 dbSNP
rs1441319021 2739 dbSNP
rs994377125 2739 dbSNP
rs1450825734 2743 dbSNP
rs369146528 2745 dbSNP
rs1382544588 2750 dbSNP
rs1029504412 2752 dbSNP
rs1299197690 2752 dbSNP
rs1444968178 2752 dbSNP
rs931477107 2754 dbSNP
rs954751002 2756 dbSNP
rs1176615849 2759 dbSNP
rs1379597805 2761 dbSNP
rs1008931242 2770 dbSNP
rs1255187243 2770 dbSNP
rs1177610583 2771 dbSNP
rs1481572684 2782 dbSNP
rs1231163921 2784 dbSNP
rs72646216 2789 dbSNP
rs1359543339 2798 dbSNP
rs887210750 2804 dbSNP
rs1243351588 2809 dbSNP
rs1358351056 2817 dbSNP
rs1166242004 2818 dbSNP
rs1308124156 2820 dbSNP
rs1366228275 2820 dbSNP
rs1008754589 2821 dbSNP
rs1298106224 2821 dbSNP
rs1405585306 2827 dbSNP
rs1041040125 2839 dbSNP
rs1402112602 2841 dbSNP
rs926175987 2846 dbSNP
rs899863921 2862 dbSNP
rs996771834 2865 dbSNP
rs1364666662 2866 dbSNP
rs989352103 2870 dbSNP
rs546465696 2886 dbSNP
rs750268774 2897 dbSNP
rs1181405432 2898 dbSNP
rs1270389562 2899 dbSNP
rs1490357336 2899 dbSNP
rs1219674168 2903 dbSNP
rs998658546 2912 dbSNP
rs559777692 2913 dbSNP
rs1260957120 2919 dbSNP
rs1218299445 2943 dbSNP
rs950236642 2947 dbSNP
rs1306849704 2953 dbSNP
rs1044156398 2955 dbSNP
rs1347977598 2963 dbSNP
rs1376767242 2966 dbSNP
rs1031359242 2970 dbSNP
rs927052273 2973 dbSNP
rs1229424091 2978 dbSNP
rs1314877030 2980 dbSNP
rs1320009112 2983 dbSNP
rs1290860742 2989 dbSNP
rs1455118482 2991 dbSNP
rs1343240210 2994 dbSNP
rs940999911 2998 dbSNP
rs959797228 3003 dbSNP
rs533242267 3005 dbSNP
rs1431447688 3009 dbSNP
rs993022417 3016 dbSNP
rs531226007 3021 dbSNP
rs1459304000 3033 dbSNP
rs1196501772 3035 dbSNP
rs1237376948 3039 dbSNP
rs1483510002 3041 dbSNP
rs1206548523 3047 dbSNP
rs552159715 3048 dbSNP
rs559959730 3049 dbSNP
rs183904698 3054 dbSNP
rs1267860909 3059 dbSNP
rs1204783095 3064 dbSNP
rs1410903018 3066 dbSNP
rs377183055 3067 dbSNP
rs564087473 3070 dbSNP
rs1222911723 3072 dbSNP
rs1170847995 3078 dbSNP
rs531505941 3079 dbSNP
rs920190736 3082 dbSNP
rs1168926962 3104 dbSNP
rs1361579153 3105 dbSNP
rs931447624 3114 dbSNP
rs1407675240 3119 dbSNP
rs1051490444 3124 dbSNP
rs398088140 3130 dbSNP
rs72646217 3130 dbSNP
rs1174219844 3138 dbSNP
rs1373127577 3141 dbSNP
rs1465062702 3141 dbSNP
rs1194743004 3142 dbSNP
rs1426362455 3144 dbSNP
rs1247090936 3146 dbSNP
rs1449319824 3148 dbSNP
rs890948179 3150 dbSNP
rs1241795340 3151 dbSNP
rs1200409955 3152 dbSNP
rs1340746884 3156 dbSNP
rs72646218 3161 dbSNP
rs775655794 3165 dbSNP
rs1377713817 3173 dbSNP
rs908734217 3173 dbSNP
rs528584384 3174 dbSNP
rs1017626953 3175 dbSNP
rs1453044378 3176 dbSNP
rs567759784 3185 dbSNP
rs1334499270 3189 dbSNP
rs944127393 3191 dbSNP
rs1395349873 3193 dbSNP
rs1397208302 3194 dbSNP
rs878897617 3197 dbSNP
rs1169130418 3198 dbSNP
rs764033983 3206 dbSNP
rs1414231945 3207 dbSNP
rs762676016 3212 dbSNP
rs1278970042 3217 dbSNP
rs1446774365 3228 dbSNP
rs565949716 3228 dbSNP
rs899790581 3229 dbSNP
rs996807686 3232 dbSNP
rs1438898312 3235 dbSNP
rs1253359648 3236 dbSNP
rs72646219 3261 dbSNP
rs150254333 3263 dbSNP
rs1292709328 3274 dbSNP
rs1357604386 3277 dbSNP
rs1257130537 3279 dbSNP
rs989075568 3282 dbSNP
rs1330818265 3283 dbSNP
rs1312563774 3284 dbSNP
rs1389135192 3285 dbSNP
rs147713754 3292 dbSNP
rs998751820 3295 dbSNP
rs539126815 3298 dbSNP
rs1303285677 3299 dbSNP
rs1031452496 3302 dbSNP
rs1482916538 3305 dbSNP
rs1383074183 3315 dbSNP
rs368883109 3325 dbSNP
rs980284275 3325 dbSNP
rs1193723105 3330 dbSNP
rs1013966965 3332 dbSNP
rs1023145328 3333 dbSNP
rs969721965 3336 dbSNP
rs941125973 3337 dbSNP
rs1269655407 3341 dbSNP
rs1419167146 3341 dbSNP
rs1489916820 3344 dbSNP
rs973085987 3344 dbSNP
rs1415397966 3345 dbSNP
rs1178761416 3346 dbSNP
rs1351170848 3347 dbSNP
rs1357905735 3354 dbSNP
rs1434684408 3358 dbSNP
rs920283730 3361 dbSNP
rs576659945 3370 dbSNP
rs1283364062 3371 dbSNP
rs766172246 3372 dbSNP
rs984490713 3373 dbSNP
rs1347699529 3376 dbSNP
rs1322485229 3380 dbSNP
rs1387561434 3384 dbSNP
rs908706658 3384 dbSNP
rs1398314235 3386 dbSNP
rs944204709 3388 dbSNP
rs1472547363 3397 dbSNP
rs751071676 3400 dbSNP
rs1479499700 3405 dbSNP
rs754501609 3406 dbSNP
rs932630944 3408 dbSNP
rs1194197247 3425 dbSNP
rs138887927 3430 dbSNP
rs1286052073 3431 dbSNP
rs1043019925 3433 dbSNP
rs1347013892 3437 dbSNP
rs1217271034 3447 dbSNP
rs1287462113 3449 dbSNP
rs1263682273 3451 dbSNP
rs1224748075 3452 dbSNP
rs1364900021 3452 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions MCF7
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRR1045082. RNA binding protein: AGO2. Condition:Untreated ...

- Farazi TA; Ten Hoeve JJ; Brown M; et al., 2014, Genome biology.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' guguGAGUACACCG-GGGGUCgu 5'
              |||   |  | ||||||  
Target 5' cuacCUCUCCUCACACCCCAG-- 3'
 		13 - 33
2 
miRNA  3' gugugaguacaccgGGGGUCGu 5'
                        |:|| || 
Target 5' ------------uaCUCCUGCu 3'
 		1 - 10
Article - Farazi TA; Ten Hoeve JJ; Brown M; et al.
- Genome biology, 2014
BACKGROUND: Various microRNAs (miRNAs) are up- or downregulated in tumors. However, the repression of cognate miRNA targets responsible for the phenotypic effects of this dysregulation in patients remains largely unexplored. To define miRNA targets and associated pathways, together with their relationship to outcome in breast cancer, we integrated patient-paired miRNA-mRNA expression data with a set of validated miRNA targets and pathway inference. RESULTS: To generate a biochemically-validated set of miRNA-binding sites, we performed argonaute-2 photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation (AGO2-PAR-CLIP) in MCF7 cells. We then defined putative miRNA-target interactions using a computational model, which ranked and selected additional TargetScan-predicted interactions based on features of our AGO2-PAR-CLIP binding-site data. We subselected modeled interactions according to the abundance of their constituent miRNA and mRNA transcripts in tumors, and we took advantage of the variability of miRNA expression within molecular subtypes to detect miRNA repression. Interestingly, our data suggest that miRNA families control subtype-specific pathways; for example, miR-17, miR-19a, miR-25, and miR-200b show high miRNA regulatory activity in the triple-negative, basal-like subtype, whereas miR-22 and miR-24 do so in the HER2 subtype. An independent dataset validated our findings for miR-17 and miR-25, and showed a correlation between the expression levels of miR-182 targets and overall patient survival. Pathway analysis associated miR-17, miR-19a, and miR-200b with leukocyte transendothelial migration. CONCLUSIONS: We combined PAR-CLIP data with patient expression data to predict regulatory miRNAs, revealing potential therapeutic targets and prognostic markers in breast cancer.
LinkOut: [PMID: 24398324]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HCT116
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in ERX177600. RNA binding protein: AGO2. Condition:p53_V_Ago_CLIP_2_2 PAR-CLIP data was present in ERX177606. RNA binding protein: AGO2. Condition:KO_V_AGO_CLIP_2_8 PAR-CLIP data was present in ERX177612. RNA binding protein: AGO2. Condition:p53_V_AGO_CLIP_3_2 PAR-CLIP data was present in ERX177613. RNA binding protein: AGO2. Condition:KO_D_AGO_CLIP_3_3 PAR-CLIP data was present in ERX177618. RNA binding protein: AGO2. Condition:KO_V_AGO_CLIP_3_8 PAR-CLIP data was present in ERX177624. RNA binding protein: AGO2. Condition:p53_V_AGO_CLIP_4_2 PAR-CLIP data was present in ERX177625. RNA binding protein: AGO2. Condition:KO_D_AGO_CLIP_4_3 PAR-CLIP data was present in ERX177630. RNA binding protein: AGO2. Condition:KO_V_AGO_CLIP_4_8 PAR-CLIP data was present in ERX177633. RNA binding protein: AGO2. Condition:KO_D_AGO_CLIP_4_11 ...

- Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research.

Article - Krell J; Stebbing J; Carissimi C; Dabrowska et al.
- Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
CLIP-seq Support 1 for dataset GSM4903825
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / PID14_NS
Location of target site NM_001174088 | 3UTR | AGUGGAAGAGACAUCCCUUGACUUUUGUGGCCUGGGGGAGGGGUAGUGCUCCACAGCUUUUCCUUCCCCACCCCCCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161237
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset SRR1045082
Method / RBP PAR-CLIP / AGO2
Cell line / Condition MCF7 / Untreated
Location of target site ENST00000341724.6 | 3UTR | UACUCCUGCUGUCUACCUCUCCUCACACCCCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 24398324 / SRX388831
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
321 hsa-miR-4731-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT081189 MIDN midnolin 2 4
MIRT113400 RAB5B RAB5B, member RAS oncogene family 2 8
MIRT153789 NCOA3 nuclear receptor coactivator 3 2 2
MIRT169837 GIGYF1 GRB10 interacting GYF protein 1 2 6
MIRT441540 CHD7 chromodomain helicase DNA binding protein 7 2 2
MIRT443470 ACPP acid phosphatase, prostate 2 2
MIRT443851 RGS6 regulator of G protein signaling 6 2 2
MIRT444416 EMC1 ER membrane protein complex subunit 1 2 2
MIRT444838 PDE6D phosphodiesterase 6D 2 2
MIRT444997 HRH1 histamine receptor H1 2 2
MIRT446371 THSD4 thrombospondin type 1 domain containing 4 2 2
MIRT449696 SLC10A3 solute carrier family 10 member 3 2 2
MIRT451068 PNMAL2 paraneoplastic Ma antigen family member 8B 2 2
MIRT451915 ILK integrin linked kinase 2 2
MIRT452990 CABP4 calcium binding protein 4 2 2
MIRT458034 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT460780 VPS37B VPS37B, ESCRT-I subunit 2 2
MIRT463916 WNT3 Wnt family member 3 2 2
MIRT465880 TMEM43 transmembrane protein 43 2 4
MIRT466317 THRA thyroid hormone receptor, alpha 2 2
MIRT468696 SEC22C SEC22 homolog C, vesicle trafficking protein 2 4
MIRT469129 RNF126 ring finger protein 126 2 2
MIRT472239 NFIC nuclear factor I C 2 2
MIRT479647 CD4 CD4 molecule 2 2
MIRT479734 CCND1 cyclin D1 2 6
MIRT479837 CCDC86 coiled-coil domain containing 86 2 2
MIRT483408 SPATA6 spermatogenesis associated 6 2 4
MIRT485972 RTBDN retbindin 2 2
MIRT486614 METTL6 methyltransferase like 6 2 2
MIRT487814 PER3 period circadian clock 3 2 2
MIRT488586 ST7L suppression of tumorigenicity 7 like 2 2
MIRT488673 WWP2 WW domain containing E3 ubiquitin protein ligase 2 2 2
MIRT490783 PSMD3 proteasome 26S subunit, non-ATPase 3 2 2
MIRT491356 PEX6 peroxisomal biogenesis factor 6 2 2
MIRT493539 IGDCC3 immunoglobulin superfamily DCC subclass member 3 2 4
MIRT493894 FAM43A family with sequence similarity 43 member A 2 4
MIRT494664 ARL8A ADP ribosylation factor like GTPase 8A 2 2
MIRT506353 NUP50 nucleoporin 50 2 6
MIRT508553 CEP72 centrosomal protein 72 2 4
MIRT508722 ZNF682 zinc finger protein 682 2 4
MIRT508811 GPR155 G protein-coupled receptor 155 2 2
MIRT509070 MED18 mediator complex subunit 18 2 2
MIRT509107 BMP8B bone morphogenetic protein 8b 2 6
MIRT509198 TTF2 transcription termination factor 2 2 2
MIRT509308 ZNF460 zinc finger protein 460 2 2
MIRT509341 ZNF708 zinc finger protein 708 2 2
MIRT509381 ASH2L ASH2 like histone lysine methyltransferase complex subunit 2 6
MIRT509722 EFCAB11 EF-hand calcium binding domain 11 2 4
MIRT510008 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 4
MIRT510067 C12orf49 chromosome 12 open reading frame 49 2 6
MIRT510179 BCL2L2 BCL2 like 2 2 2
MIRT511300 KIAA1551 KIAA1551 2 2
MIRT511531 HMGB1 high mobility group box 1 2 6
MIRT512018 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT514112 SERF2 small EDRK-rich factor 2 2 2
MIRT514296 FXYD5 FXYD domain containing ion transport regulator 5 2 6
MIRT514460 FANCA Fanconi anemia complementation group A 2 2
MIRT515183 CRCP CGRP receptor component 2 2
MIRT515290 C4orf3 chromosome 4 open reading frame 3 2 2
MIRT515528 QRFPR pyroglutamylated RFamide peptide receptor 2 4
MIRT515553 TMEM134 transmembrane protein 134 2 2
MIRT515619 ISY1 ISY1 splicing factor homolog 2 2
MIRT515707 ZNF321P zinc finger protein 321, pseudogene 2 2
MIRT515988 SLC30A2 solute carrier family 30 member 2 2 2
MIRT516179 POLR3A RNA polymerase III subunit A 2 4
MIRT516247 BCAS4 breast carcinoma amplified sequence 4 2 4
MIRT516505 SYTL3 synaptotagmin like 3 2 4
MIRT516586 SPHAR S-phase response (cyclin related) 2 2
MIRT516697 ODF2L outer dense fiber of sperm tails 2 like 2 2
MIRT516779 PTRF caveolae associated protein 1 2 4
MIRT516998 COX19 COX19, cytochrome c oxidase assembly factor 2 2
MIRT517094 CCDC30 coiled-coil domain containing 30 2 4
MIRT517163 SLC28A1 solute carrier family 28 member 1 2 2
MIRT517234 PRIM1 DNA primase subunit 1 2 4
MIRT517602 SAV1 salvador family WW domain containing protein 1 2 2
MIRT517631 ZNF491 zinc finger protein 491 2 2
MIRT517734 C1orf220 chromosome 1 open reading frame 220 2 2
MIRT517748 DIS3L DIS3 like exosome 3'-5' exoribonuclease 2 4
MIRT518005 RPL4 ribosomal protein L4 2 4
MIRT518184 SLC27A4 solute carrier family 27 member 4 2 2
MIRT518266 LEAP2 liver enriched antimicrobial peptide 2 2 2
MIRT518448 KIF6 kinesin family member 6 2 2
MIRT518679 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 2
MIRT518834 NEK8 NIMA related kinase 8 2 2
MIRT519142 C2orf49 chromosome 2 open reading frame 49 2 2
MIRT519250 PLA2G12A phospholipase A2 group XIIA 2 2
MIRT519369 RBM28 RNA binding motif protein 28 2 2
MIRT519410 KCNA7 potassium voltage-gated channel subfamily A member 7 2 4
MIRT519495 MAPK13 mitogen-activated protein kinase 13 2 2
MIRT520061 YIPF4 Yip1 domain family member 4 2 2
MIRT520132 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT520289 UBXN2A UBX domain protein 2A 2 2
MIRT520433 TTLL12 tubulin tyrosine ligase like 12 2 2
MIRT520553 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT520764 TCF23 transcription factor 23 2 2
MIRT520806 TAOK1 TAO kinase 1 2 2
MIRT520874 STX17 syntaxin 17 2 2
MIRT520986 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT521077 SLC25A15 solute carrier family 25 member 15 2 2
MIRT521165 SDHAF1 succinate dehydrogenase complex assembly factor 1 2 2
MIRT521213 SBNO1 strawberry notch homolog 1 2 2
MIRT521485 RAB4A RAB4A, member RAS oncogene family 2 2
MIRT521638 PROSC pyridoxal phosphate binding protein 2 2
MIRT522151 NR2F6 nuclear receptor subfamily 2 group F member 6 2 4
MIRT522300 NKAP NFKB activating protein 2 2
MIRT522445 MOB4 MOB family member 4, phocein 2 2
MIRT522493 MFN1 mitofusin 1 2 2
MIRT522877 KHSRP KH-type splicing regulatory protein 2 2
MIRT523059 HYPK huntingtin interacting protein K 2 2
MIRT523095 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT523577 GGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 2 2
MIRT523634 FOXK1 forkhead box K1 2 4
MIRT524231 DCTN6 dynactin subunit 6 2 2
MIRT524266 CYCS cytochrome c, somatic 2 2
MIRT524367 CREB1 cAMP responsive element binding protein 1 2 2
MIRT524430 CNKSR3 CNKSR family member 3 2 2
MIRT524557 CASP16 caspase 16, pseudogene 2 2
MIRT524585 CALCOCO2 calcium binding and coiled-coil domain 2 2 2
MIRT524955 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT531856 MAP2K2 mitogen-activated protein kinase kinase 2 2 2
MIRT541995 MYO1C myosin IC 2 2
MIRT542247 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT542601 YOD1 YOD1 deubiquitinase 2 2
MIRT545238 ZFAND3 zinc finger AN1-type containing 3 2 2
MIRT552183 F2RL3 F2R like thrombin or trypsin receptor 3 2 2
MIRT553520 TMEM245 transmembrane protein 245 2 2
MIRT554430 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT559138 BTF3L4 basic transcription factor 3 like 4 2 4
MIRT564062 CDT1 chromatin licensing and DNA replication factor 1 2 2
MIRT564857 ZBED3 zinc finger BED-type containing 3 2 2
MIRT565382 TGOLN2 trans-golgi network protein 2 2 2
MIRT568952 RUNX3 runt related transcription factor 3 2 2
MIRT568983 CACNA1C calcium voltage-gated channel subunit alpha1 C 2 2
MIRT569255 FAM129B family with sequence similarity 129 member B 2 2
MIRT570199 RAP1GAP2 RAP1 GTPase activating protein 2 2 2
MIRT570913 PPFIA4 PTPRF interacting protein alpha 4 2 2
MIRT571084 ZNF670 zinc finger protein 670 2 2
MIRT571456 YKT6 YKT6 v-SNARE homolog 2 2
MIRT574233 DMRT2 doublesex and mab-3 related transcription factor 2 2 2
MIRT608730 MYH9 myosin heavy chain 9 2 2
MIRT610109 IL17REL interleukin 17 receptor E like 2 2
MIRT614235 WDR53 WD repeat domain 53 2 4
MIRT626199 PNRC1 proline rich nuclear receptor coactivator 1 2 4
MIRT626325 LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 2 2
MIRT626381 BBS1 Bardet-Biedl syndrome 1 2 2
MIRT627164 ZNF48 zinc finger protein 48 2 2
MIRT633098 CBX5 chromobox 5 2 2
MIRT642246 PAK4 p21 (RAC1) activated kinase 4 2 2
MIRT643882 IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2 2
MIRT644837 SEC14L4 SEC14 like lipid binding 4 2 2
MIRT645189 POLR3F RNA polymerase III subunit F 2 4
MIRT645781 FFAR4 free fatty acid receptor 4 2 2
MIRT647144 CYP27C1 cytochrome P450 family 27 subfamily C member 1 2 2
MIRT647273 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT648743 FAM46B family with sequence similarity 46 member B 2 2
MIRT649204 KIAA1715 lunapark, ER junction formation factor 2 2
MIRT649859 WDR12 WD repeat domain 12 2 2
MIRT650814 PNPLA3 patatin like phospholipase domain containing 3 2 2
MIRT659537 CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2 2
MIRT664212 LSM3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated 2 2
MIRT664373 CYB5A cytochrome b5 type A 2 2
MIRT667395 MOB1B MOB kinase activator 1B 2 2
MIRT669465 ATL3 atlastin GTPase 3 2 2
MIRT670556 SHISA2 shisa family member 2 2 2
MIRT673104 MFSD2A major facilitator superfamily domain containing 2A 2 2
MIRT679350 LRG1 leucine rich alpha-2-glycoprotein 1 2 2
MIRT680354 GATAD1 GATA zinc finger domain containing 1 2 4
MIRT680680 ZNF785 zinc finger protein 785 2 2
MIRT680759 WDR73 WD repeat domain 73 2 2
MIRT681392 RMND1 required for meiotic nuclear division 1 homolog 2 2
MIRT681687 ABI2 abl interactor 2 2 2
MIRT681817 N4BP2L2 NEDD4 binding protein 2 like 2 2 2
MIRT682314 RAB42 RAB42, member RAS oncogene family 2 2
MIRT683308 C19orf40 Fanconi anemia core complex associated protein 24 1 1
MIRT683374 ESR2 estrogen receptor 2 2 2
MIRT683466 CCS copper chaperone for superoxide dismutase 2 2
MIRT683481 ZNF7 zinc finger protein 7 2 2
MIRT683514 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT683860 OCIAD1 OCIA domain containing 1 2 2
MIRT683926 SLC43A3 solute carrier family 43 member 3 2 2
MIRT683935 MYLK3 myosin light chain kinase 3 2 2
MIRT684068 TLR7 toll like receptor 7 2 2
MIRT684120 CEP104 centrosomal protein 104 2 2
MIRT684192 MSRB2 methionine sulfoxide reductase B2 2 2
MIRT684343 IFIT3 interferon induced protein with tetratricopeptide repeats 3 2 2
MIRT684480 GPR137B G protein-coupled receptor 137B 2 2
MIRT684565 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT684608 GTF2IRD2B GTF2I repeat domain containing 2B 2 2
MIRT684643 PDE4C phosphodiesterase 4C 2 2
MIRT684700 LRRD1 leucine rich repeats and death domain containing 1 2 2
MIRT684735 DNAJB13 DnaJ heat shock protein family (Hsp40) member B13 2 2
MIRT684911 CD28 CD28 molecule 2 2
MIRT685024 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT685186 DCTN5 dynactin subunit 5 2 2
MIRT685234 F2RL1 F2R like trypsin receptor 1 2 2
MIRT685303 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT685345 CCL5 C-C motif chemokine ligand 5 2 2
MIRT685553 TXK TXK tyrosine kinase 2 2
MIRT685570 KCNK6 potassium two pore domain channel subfamily K member 6 2 2
MIRT685651 C11orf1 chromosome 11 open reading frame 1 2 2
MIRT685697 BHMT2 betaine--homocysteine S-methyltransferase 2 2 2
MIRT685731 C12orf65 chromosome 12 open reading frame 65 2 2
MIRT685873 RTN2 reticulon 2 2 2
MIRT685937 PTGIS prostaglandin I2 synthase 2 2
MIRT686095 TNIP3 TNFAIP3 interacting protein 3 2 2
MIRT686147 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT686271 WWC1 WW and C2 domain containing 1 2 2
MIRT686307 VPS53 VPS53, GARP complex subunit 2 2
MIRT686349 USP15 ubiquitin specific peptidase 15 2 2
MIRT686377 UBE2V2 ubiquitin conjugating enzyme E2 V2 2 2
MIRT686431 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT686477 TRIOBP TRIO and F-actin binding protein 2 2
MIRT686515 TRAF3IP2 TRAF3 interacting protein 2 2 2
MIRT686682 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT686818 SLC7A11 solute carrier family 7 member 11 2 2
MIRT686904 SGTB small glutamine rich tetratricopeptide repeat containing beta 2 2
MIRT686974 SERINC1 serine incorporator 1 2 2
MIRT687035 RNF115 ring finger protein 115 2 2
MIRT687067 RABGAP1L RAB GTPase activating protein 1 like 2 2
MIRT687240 PDHB pyruvate dehydrogenase E1 beta subunit 2 2
MIRT687494 NFATC2IP nuclear factor of activated T-cells 2 interacting protein 2 2
MIRT687591 MANEAL mannosidase endo-alpha like 2 2
MIRT687635 LRIF1 ligand dependent nuclear receptor interacting factor 1 2 2
MIRT687673 LMBR1L limb development membrane protein 1 like 2 2
MIRT687849 ISCA2 iron-sulfur cluster assembly 2 2 2
MIRT687918 HOOK3 hook microtubule tethering protein 3 2 2
MIRT687974 GTF2IRD2 GTF2I repeat domain containing 2 2 2
MIRT688105 GK5 glycerol kinase 5 (putative) 2 2
MIRT688115 GEMIN8 gem nuclear organelle associated protein 8 2 2
MIRT688148 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT688263 FAM213A family with sequence similarity 213 member A 2 2
MIRT688456 DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 2 2
MIRT688497 DDI2 DNA damage inducible 1 homolog 2 2 2
MIRT688558 DCAF16 DDB1 and CUL4 associated factor 16 2 2
MIRT688668 CPT1A carnitine palmitoyltransferase 1A 2 2
MIRT689057 AGMAT agmatinase 2 2
MIRT689075 ADO 2-aminoethanethiol dioxygenase 2 2
MIRT689108 ZBTB25 zinc finger and BTB domain containing 25 2 2
MIRT689161 ZNF665 zinc finger protein 665 2 2
MIRT689788 GTF2H3 general transcription factor IIH subunit 3 2 2
MIRT689835 HIST1H2BJ histone cluster 1 H2B family member j 2 2
MIRT690061 MBD1 methyl-CpG binding domain protein 1 2 2
MIRT690727 IRAK4 interleukin 1 receptor associated kinase 4 2 2
MIRT690974 ZNF578 zinc finger protein 578 2 2
MIRT691066 NUGGC nuclear GTPase, germinal center associated 2 2
MIRT691315 KIAA1841 KIAA1841 2 2
MIRT691485 FOXRED2 FAD dependent oxidoreductase domain containing 2 2 2
MIRT691568 CCDC125 coiled-coil domain containing 125 2 2
MIRT691601 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT692059 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT692099 CXorf38 chromosome X open reading frame 38 2 4
MIRT692311 RFK riboflavin kinase 2 2
MIRT692371 LY6G5B lymphocyte antigen 6 family member G5B 2 2
MIRT692432 METTL8 methyltransferase like 8 2 2
MIRT692468 APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 2 2
MIRT692532 PARD3 par-3 family cell polarity regulator 2 2
MIRT692594 GDF5OS growth differentiation factor 5 opposite strand 2 2
MIRT692776 SYNPO2L synaptopodin 2 like 2 2
MIRT692810 C1orf50 chromosome 1 open reading frame 50 2 2
MIRT692868 RBM41 RNA binding motif protein 41 2 2
MIRT693131 THEM4 thioesterase superfamily member 4 2 2
MIRT693313 TRIM58 tripartite motif containing 58 2 2
MIRT693497 MOB3A MOB kinase activator 3A 2 2
MIRT694101 ZNF446 zinc finger protein 446 2 2
MIRT694173 POLM DNA polymerase mu 2 2
MIRT694186 ZNF347 zinc finger protein 347 2 2
MIRT694444 TNFAIP8L1 TNF alpha induced protein 8 like 1 2 2
MIRT694653 C14orf119 chromosome 14 open reading frame 119 2 2
MIRT694802 STX4 syntaxin 4 2 2
MIRT694922 ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2 2
MIRT695174 SLC25A33 solute carrier family 25 member 33 2 2
MIRT695305 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 4
MIRT695656 MAN2B2 mannosidase alpha class 2B member 2 2 2
MIRT695823 ABCG8 ATP binding cassette subfamily G member 8 2 2
MIRT695964 EIF2B2 eukaryotic translation initiation factor 2B subunit beta 2 2
MIRT696174 GNB5 G protein subunit beta 5 2 2
MIRT696433 SUGP1 SURP and G-patch domain containing 1 2 2
MIRT696610 CRIPT CXXC repeat containing interactor of PDZ3 domain 2 2
MIRT696854 UBOX5 U-box domain containing 5 2 2
MIRT696896 C14orf105 coiled-coil domain containing 198 2 2
MIRT697382 ZMAT3 zinc finger matrin-type 3 2 2
MIRT697529 ZBTB46 zinc finger and BTB domain containing 46 2 2
MIRT697973 TSPAN6 tetraspanin 6 2 2
MIRT698325 TMEM127 transmembrane protein 127 2 2
MIRT698915 SPEM1 spermatid maturation 1 2 2
MIRT699257 SLC6A4 solute carrier family 6 member 4 2 2
MIRT699311 SLC35F5 solute carrier family 35 member F5 2 4
MIRT699624 SH3BP5 SH3 domain binding protein 5 2 2
MIRT699688 SF3B3 splicing factor 3b subunit 3 2 2
MIRT700040 RPL14 ribosomal protein L14 2 2
MIRT700095 RNF19B ring finger protein 19B 2 2
MIRT700498 PTPN4 protein tyrosine phosphatase, non-receptor type 4 2 2
MIRT700747 PLAA phospholipase A2 activating protein 2 2
MIRT701103 PAPD5 poly(A) RNA polymerase D5, non-canonical 2 2
MIRT701568 MYPN myopalladin 2 2
MIRT701692 MYADM myeloid associated differentiation marker 2 2
MIRT701815 MRPL37 mitochondrial ribosomal protein L37 2 2
MIRT702435 KIAA1549 KIAA1549 2 2
MIRT702518 KCND3 potassium voltage-gated channel subfamily D member 3 2 2
MIRT702954 HIP1 huntingtin interacting protein 1 2 2
MIRT703079 GPRIN3 GPRIN family member 3 2 2
MIRT704106 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT704138 DNAL1 dynein axonemal light chain 1 2 2
MIRT704187 LDHD lactate dehydrogenase D 2 2
MIRT704754 CDKN2AIPNL CDKN2A interacting protein N-terminal like 2 2
MIRT705075 C4orf29 abhydrolase domain containing 18 2 2
MIRT705342 ATP1B3 ATPase Na+/K+ transporting subunit beta 3 2 2
MIRT706274 SLC35F6 solute carrier family 35 member F6 2 2
MIRT706397 HAS2 hyaluronan synthase 2 2 2
MIRT706431 LIAS lipoic acid synthetase 2 2
MIRT706506 MTMR9 myotubularin related protein 9 2 2
MIRT707586 PCNXL2 pecanex homolog 2 2 2
MIRT708361 CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2 2
MIRT708444 MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2 2
MIRT709915 GRIK3 glutamate ionotropic receptor kainate type subunit 3 2 2
MIRT712607 BHLHA15 basic helix-loop-helix family member a15 2 2
MIRT716540 GOLGA2 golgin A2 2 2
MIRT721623 VDR vitamin D receptor 2 2
MIRT724887 MVK mevalonate kinase 2 2
MIRT725257 PARVB parvin beta 2 2
MIRT755885 RPLP0 ribosomal protein lateral stalk subunit P0 3 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4731 Fluorouracil 3385 NSC19893 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4731 Gemcitabine 60750 NSC613327 approved sensitive High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4731 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-4731-5p Anthracycline 30323 NSC82151 approved resistant High Breast Cancer tissue
hsa-miR-4731-5p Fluorouracil 3385 NSC19893 approved resistant High Breast Cancer tissue
hsa-miR-4731-5p Cyclophosphamide 2907 NSC26271 approved resistant High Breast Cancer tissue
hsa-miR-4731-5p Methotrexate 126941 NSC740 approved resistant High Breast Cancer tissue
hsa-miR-4731-5p Taxol 36314 NSC125973 approved resistant High Breast Cancer tissue
hsa-miR-4731-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-4731-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4731-5p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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