miRTarBase - #MIRT175463


—
pre-miRNA Information
pre-miRNA hsa-mir-506   
Genomic Coordinates chrX: 147230720 - 147230843
Synonyms MIRN506, hsa-mir-506, MIR506
Description Homo sapiens miR-506 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-506-5p
Sequence 35| UAUUCAGGAAGGUGUUACUUAA |56
Evidence Not_experimental
Experiments
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs782463365 2 dbSNP
rs781802841 18 dbSNP
rs782722056 21 dbSNP
rs782039395 22 dbSNP
Putative Targets

Gene Information
Gene Symbol ZBTB33   
Synonyms ZNF-kaiso, ZNF348
Description zinc finger and BTB domain containing 33
Transcript NM_001184742   
Other Transcripts NM_006777   
Expression
Putative miRNA Targets on ZBTB33
3'UTR of ZBTB33
(miRNA target sites are highlighted)		 
>ZBTB33|NM_001184742|3'UTR
   1 ACTCCTTTGAAATACTAGAAAGTTTTGTTTTGGATGATGGGGCAGGGGTTTCAGAAGATCTGTAAAACAAATTAAGGTGC
  81 GAACAAGTTAATTTGATCTGCCACATTATCTGAAGGAAGTGTAGTGGGATTTTTGTTGATAATTTTTAGAAGCAAATTTT
 161 CCTGAAAGTTTTGAGTAGAGGTGAGACCCCCTCCCCAAGTATCTGTTTATATAGTTAGTTTTCAGCTCATTTAAAAGAGG
 241 CAAAAATTAAAAGCTTGGAGAGATAGTTTCCTGAATAGAATTTGAAGCAGTCTGAATGTTCTTTGAAAATAACTGGAGTT
 321 ATTAGCATACCCTAGTACATCTTACAGCTTTCCCCTTCCATGTTAGCACTTTACTGCTGAATTCTCAATTTTCTTAACAT
 401 TGAGACAATAAATGTGTGTTTTGTCTTGTATATGGCATAAAGAGTAAATAAGTTTTAGAGTTGTTCTGGAAAATGTCAGA
 481 ATAAGTCAGTACTTGGGTTGTGTAATCTGCTAGTCCAAGCGAACAGCAACCTCCTGCTACCCTCCCTCTATGAAAATAGC
 561 CATGCAGACAAGTCTCTCATCTGAAGAACAAATTAGATTTAGCTAATTAGAATTAATCCTGGCTTTCATTGCCATAGTCT
 641 GTAAAAGACTTTGGTGGCTAGACCACTTTATACCTTCGCAGTGTGGTCTCTGGGGGCAAAAAACTAATGAAAACAATCTC
 721 TGTAATGGCAGATAGGAGGAGATGAAAAGTTCTGTTGCATGGATTTTTAATTCTCTGGCTACCACATAGTAGAGAATGGA
 801 ATGAAGATTTCCTTTTGGCTTCTTAAGGTTAAAAATATTCCCATGAACATGAAAATTTTCAAATTTTGAATCTGAAAGCC
 881 ACCAAATGTATCTTTATGTATAAATCCTTGTAAATGATAGATTCCATGGGTGAGACTTTACATATTTTGGGTGGGAGGCT
 961 ACTGGCATATATTTTTAAATGTTCATATTGCGTAGAATCTCCACTAGGAAGTCTTTATTTGAAATAGTTGAATCAGTGAT
1041 CTAGTATTTTCCTTTCGGCAAGATTTGTTAGGTTTTTACCCCTTCTAAAATAAGTTTTATTCCATCTGCAAATTGCTGCA
1121 ATATTATAGTAATCAGAAACTACATAAGGAATGTTATATAGGCTTGTCAGTTCCCATTTTTCTTGACAACAATAAATACC
1201 ACTTTTAAAAATGACACATATTTAAACACTTAGAAAATAAAGTTAACACTTACTGAAGTGCTAGTACTAAACTGTGCTAG
1281 TACTAAAAGAAAACAGGTTGGAACATACATATAGCCTAGCATTTATAACAGAATTGTTGAACGTCTGTAAATGATTTTTT
1361 TTTTTTTTGCAAAGGAAAAAATTGATACTGGAAAAGATTGTTGTGCATAGTTATTAGTCATTTGTAACCTTGCTTAAGTA
1441 TTTCTTAGTCCAACATAGATATTTTCTTTCTCCTGACCATGTATTTTAAAATATAGTCTATTTCTTGACTTTGAACTTAA
1521 AGCTTTAATCATAATTTCTCATGTATACATCGTTCTTCTGATGGTAAGCTGGATTTGAAGGTAGTGGTTTCAGTGTTTCT
1601 TAAGTTGGTAGCTGAGGGTATCAGGCATCAGTTCATGCAATAATACAAGAAAAAAAATCCTTTGCTTGCCAAGAGGTAGA
1681 GTGATGTGCATTTATCTGTTTTCTGTTCTGTAAGTCTAGACCTTCAAACCATTTGTAAACTAACCCCTGGGAAATTTGAA
1761 ATTACCTGATAACTTAAGACTCTGTGATCTCTGGAATCACCATATGTTTCTTTTTTGTGTAGATATTAATAACATTACTC
1841 TTTGACTATAGTGTGCACTCTGAAATGTACTCAGTGAAAATTTGTTTTGAGTTTCATTAATGCTATTTCACCAGTTAGAC
1921 ATAATTACTTCTACCGATGTGAATGATACGGATGCCGGCAGAGCTTCCAGATCTTTCAGACTCAACTGCTAGGTCAATTA
2001 GTTTGTCATAATAAAACTTGGCAGATTCTACAAGTCTATTATGACAAACCAGGAACTAATTCTATAATGGAAAACTATCC
2081 ATTCTGAATAATAGGTATGTAATTATTTGCTGCTGCTGCTGTGCTCTGTAAATTCTGAATATGACATTTAAACTCTGTGC
2161 CTACTAAAGGTATCTTCTGGAGTTTTTGGGAGGAGAGAAACTGGAAAATTAAATTGTATTTTTGCCAGAAGACTCTTACT
2241 TGCATGTGTCTCAGGGTCTTCAGTTTTTCTATAAGTTTCCATATCCAAAGTTCAGAATTCATGTGAAATACTTCTTTGGG
2321 GCAAAAGTCCTTCATTCCTGGTATTTATTGGATTGGAAATCTGTAGCAAGATGCTGTTTAAAATTACCATATTGTTTTTT
2401 TATCTTATACTTAGCTCTCTGGCTATTGAACTTCCTTTTCTTGTTTGAAGTTAGCTTCAAATTTGCTCCTATGCTAAATT
2481 ACCTGTAAATATTCTGGATAGGAACTACTTGAAATAGTAATTTGTTAAAAGATATGACAAAATGAAAATGCTTAAACTAC
2561 AGAAATTTAAAAATGCCATAACAATCTTGCGAGACTAACTTTAAAATATACTTTAAATGATTATTATGATTTTGGTGGTA
2641 ACGATCCCCCACACACAACCACTATGAAGAAATAATGCCGCATTTTTCCCCCATTGTACCAAAAAGATAAAAAAATGGTA
2721 AACACTGATCAAGGTATTTTGTATTGTCAAGGCATGCATATTCTAAAGAATTAAATGCTAACTTAACAGCACTGGCTTTC
2801 TGGCTGGTCAACTATATGAAACCTTGTTCATTCCTCCGAGTACTGTAATGTTCACACTTGTACAATCTTCCCTGTCATGA
2881 CTTTAAGTTCTACTTTTCATTAACCATGGCCTGATATTAGTTCTTAGAGCTTCTTGTGGCAAAAATAAAATGATTTAATT
2961 CTAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aaUUCAUUGUGGAAGGACUUAu 5'
            :|| :|:| :||||||||| 
Target 5' tgGAGAGATAGTTTCCTGAATa 3'
 256 - 277 168.00 -18.30
2 
miRNA  3' aaUUCAUUGUGGAAGGACUUau 5'
            ||| || |::||||||||  
Target 5' agAAGCAA-ATTTTCCTGAAag 3'
 148 - 168 151.00 -12.20
3 
miRNA  3' aaUUCAUUGUGGAAGGACUUAu 5'
            || ||   || |:|||||| 
Target 5' aaAACTA--TCCATTCTGAATa 3'
 2071 - 2090 140.00 -12.00
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs782263109 2 dbSNP
rs782218082 5 dbSNP
rs782337560 10 dbSNP
rs781927736 16 dbSNP
rs1434113200 20 dbSNP
rs782173779 26 dbSNP
rs782803950 38 dbSNP
rs782000872 39 dbSNP
rs782691586 45 dbSNP
rs1419953267 58 dbSNP
rs1175337468 81 dbSNP
rs781906430 82 dbSNP
rs1258054183 85 dbSNP
rs1210112347 87 dbSNP
rs374847229 90 dbSNP
rs1025109821 91 dbSNP
rs1287599559 93 dbSNP
rs782536589 101 dbSNP
rs970420105 104 dbSNP
rs1240381841 134 dbSNP
rs1004993482 141 dbSNP
rs1306720759 170 dbSNP
rs1389971375 178 dbSNP
rs139977503 181 dbSNP
rs1313978842 190 dbSNP
rs1414739027 210 dbSNP
rs1373689589 212 dbSNP
rs782244755 213 dbSNP
rs1300163356 217 dbSNP
rs1454502645 218 dbSNP
rs1363376585 219 dbSNP
rs961956166 224 dbSNP
rs974300245 227 dbSNP
rs782211281 234 dbSNP
rs1425288257 256 dbSNP
rs1418350985 260 dbSNP
rs782323742 265 dbSNP
rs1484679734 273 dbSNP
rs1264692042 284 dbSNP
rs1205275948 310 dbSNP
rs371662050 331 dbSNP
rs1485262195 335 dbSNP
rs1258522588 338 dbSNP
rs182404987 346 dbSNP
rs1323837867 383 dbSNP
rs781925693 400 dbSNP
rs1233182888 410 dbSNP
rs782172272 412 dbSNP
rs67998482 413 dbSNP
rs1382795622 421 dbSNP
rs1384379885 429 dbSNP
rs1287296370 430 dbSNP
rs1459679555 443 dbSNP
rs1164025878 445 dbSNP
rs1394918552 445 dbSNP
rs1474183297 456 dbSNP
rs187089793 467 dbSNP
rs1193827354 479 dbSNP
rs1427357731 486 dbSNP
rs573793410 493 dbSNP
rs1211230360 497 dbSNP
rs1468679892 507 dbSNP
rs782008746 510 dbSNP
rs1274180900 522 dbSNP
rs73607657 523 dbSNP
rs1333149942 531 dbSNP
rs1272387192 536 dbSNP
rs1228836798 545 dbSNP
rs1293587595 558 dbSNP
rs1388730577 572 dbSNP
rs1372089608 596 dbSNP
rs372539982 598 dbSNP
rs1459624820 604 dbSNP
rs1402221478 626 dbSNP
rs1168384941 629 dbSNP
rs1461455254 635 dbSNP
rs192233362 650 dbSNP
rs1200441242 667 dbSNP
rs1454441857 671 dbSNP
rs7882480 678 dbSNP
rs1191388780 698 dbSNP
rs1467389656 711 dbSNP
rs1275603926 717 dbSNP
rs1196866900 730 dbSNP
rs1339376356 730 dbSNP
rs782519453 734 dbSNP
rs373311722 755 dbSNP
rs1236502362 763 dbSNP
rs1371836397 779 dbSNP
rs1302891547 787 dbSNP
rs1439021919 788 dbSNP
rs1378794263 796 dbSNP
rs1329349587 798 dbSNP
rs1390733394 810 dbSNP
rs781975565 813 dbSNP
rs1394327810 824 dbSNP
rs1174247669 828 dbSNP
rs782085041 849 dbSNP
rs1434730208 863 dbSNP
rs782761167 871 dbSNP
rs1393992385 891 dbSNP
rs1171331249 905 dbSNP
rs1441219540 911 dbSNP
rs781829693 924 dbSNP
rs1183074099 940 dbSNP
rs1437616575 943 dbSNP
rs1248964085 945 dbSNP
rs1213670126 951 dbSNP
rs1348632209 953 dbSNP
rs1279754445 968 dbSNP
rs1232339655 988 dbSNP
rs782071210 990 dbSNP
rs58628009 992 dbSNP
rs1333777275 995 dbSNP
rs1314606814 997 dbSNP
rs57741634 1008 dbSNP
rs1415369455 1026 dbSNP
rs1374301625 1028 dbSNP
rs1310609136 1035 dbSNP
rs182982429 1036 dbSNP
rs1408179180 1042 dbSNP
rs1157650044 1051 dbSNP
rs1469903835 1058 dbSNP
rs1362454780 1074 dbSNP
rs1190657599 1081 dbSNP
rs1486312267 1083 dbSNP
rs1256880073 1087 dbSNP
rs1208904212 1101 dbSNP
rs1448815012 1109 dbSNP
rs188734277 1115 dbSNP
rs1204793480 1117 dbSNP
rs1348241509 1122 dbSNP
rs1294958633 1127 dbSNP
rs782807099 1128 dbSNP
rs1291371867 1160 dbSNP
rs1432216758 1169 dbSNP
rs11537755 1177 dbSNP
rs1317147011 1186 dbSNP
rs193208167 1189 dbSNP
rs1386880475 1196 dbSNP
rs1167623165 1207 dbSNP
rs782458296 1214 dbSNP
rs1417685530 1216 dbSNP
rs782529940 1218 dbSNP
rs1186435885 1223 dbSNP
rs1476402742 1233 dbSNP
rs1242821871 1234 dbSNP
rs184955675 1242 dbSNP
rs1445556526 1248 dbSNP
rs1274812189 1251 dbSNP
rs1214018366 1258 dbSNP
rs1333907290 1313 dbSNP
rs879990962 1322 dbSNP
rs1216289898 1330 dbSNP
rs1271142080 1330 dbSNP
rs1361999665 1346 dbSNP
rs1269128088 1348 dbSNP
rs1428198136 1351 dbSNP
rs1163239082 1355 dbSNP
rs1372807266 1355 dbSNP
rs1412182041 1355 dbSNP
rs782587377 1355 dbSNP
rs1420304718 1368 dbSNP
rs782280380 1369 dbSNP
rs1186074537 1370 dbSNP
rs1474470927 1371 dbSNP
rs1255059802 1376 dbSNP
rs5910810 1377 dbSNP
rs1250950614 1383 dbSNP
rs1206510866 1387 dbSNP
rs1308063801 1407 dbSNP
rs1271673770 1414 dbSNP
rs1212226648 1419 dbSNP
rs1349433142 1429 dbSNP
rs1303620983 1434 dbSNP
rs1439742140 1454 dbSNP
rs1370693053 1486 dbSNP
rs561168130 1492 dbSNP
rs188936790 1518 dbSNP
rs1292210710 1531 dbSNP
rs1444986746 1543 dbSNP
rs1355558548 1545 dbSNP
rs1170377506 1550 dbSNP
rs142166317 1552 dbSNP
rs1174465403 1553 dbSNP
rs781832263 1553 dbSNP
rs1454036123 1561 dbSNP
rs1264986563 1580 dbSNP
rs782163990 1592 dbSNP
rs1178796853 1626 dbSNP
rs1480838598 1627 dbSNP
rs1232171970 1639 dbSNP
rs1202380513 1640 dbSNP
rs373167622 1647 dbSNP
rs782237939 1647 dbSNP
rs1280467001 1650 dbSNP
rs1486341941 1650 dbSNP
rs1233097618 1651 dbSNP
rs1345382933 1658 dbSNP
rs1225776611 1660 dbSNP
rs782347618 1675 dbSNP
rs1374538609 1703 dbSNP
rs1298066875 1706 dbSNP
rs1408580396 1726 dbSNP
rs782457040 1727 dbSNP
rs1377329998 1736 dbSNP
rs1313622295 1745 dbSNP
rs782590085 1747 dbSNP
rs192250180 1750 dbSNP
rs782179006 1751 dbSNP
rs1419398733 1765 dbSNP
rs1407013838 1773 dbSNP
rs1179881753 1800 dbSNP
rs1476181929 1833 dbSNP
rs782176537 1834 dbSNP
rs1257602814 1835 dbSNP
rs1209450354 1841 dbSNP
rs1484413964 1856 dbSNP
rs1262074955 1860 dbSNP
rs1216106052 1873 dbSNP
rs1317865614 1875 dbSNP
rs1306799058 1881 dbSNP
rs782436081 1897 dbSNP
rs1227079152 1901 dbSNP
rs1357986196 1911 dbSNP
rs1294448053 1914 dbSNP
rs782014405 1916 dbSNP
rs782428185 1932 dbSNP
rs782671981 1936 dbSNP
rs868983808 1937 dbSNP
rs151207016 1940 dbSNP
rs1344359953 1945 dbSNP
rs1156770603 1948 dbSNP
rs1476069320 1948 dbSNP
rs1418418584 1950 dbSNP
rs1187166307 1952 dbSNP
rs184089476 1956 dbSNP
rs782273169 1957 dbSNP
rs782380253 1958 dbSNP
rs1186723113 1969 dbSNP
rs1485372920 1980 dbSNP
rs1267885618 1996 dbSNP
rs1207143894 2008 dbSNP
rs188822549 2019 dbSNP
rs781963460 2020 dbSNP
rs1274296294 2021 dbSNP
rs1233240886 2022 dbSNP
rs1338743085 2029 dbSNP
rs1297874468 2044 dbSNP
rs540993656 2046 dbSNP
rs1361454970 2047 dbSNP
rs1318805973 2050 dbSNP
rs1462779006 2052 dbSNP
rs1394985917 2053 dbSNP
rs1164091615 2057 dbSNP
rs1456375996 2074 dbSNP
rs1374282262 2078 dbSNP
rs1427412704 2095 dbSNP
rs781968682 2096 dbSNP
rs1195134438 2099 dbSNP
rs1470072012 2108 dbSNP
rs782079385 2119 dbSNP
rs1254059668 2156 dbSNP
rs1209741130 2166 dbSNP
rs1354930446 2202 dbSNP
rs1253604322 2205 dbSNP
rs868950550 2207 dbSNP
rs782712662 2213 dbSNP
rs1341577228 2220 dbSNP
rs1295633293 2239 dbSNP
rs1443434140 2241 dbSNP
rs1371434762 2268 dbSNP
rs1325042869 2282 dbSNP
rs1385000654 2311 dbSNP
rs781784067 2317 dbSNP
rs1168437808 2325 dbSNP
rs1460999923 2362 dbSNP
rs1387813322 2384 dbSNP
rs782150371 2394 dbSNP
rs1454479206 2395 dbSNP
rs1396052573 2402 dbSNP
rs1198521343 2417 dbSNP
rs1450253928 2426 dbSNP
rs1253230335 2469 dbSNP
rs1196921066 2470 dbSNP
rs1482752554 2480 dbSNP
rs1272634065 2490 dbSNP
rs1236756459 2506 dbSNP
rs1348955915 2507 dbSNP
rs1274489370 2535 dbSNP
rs782799978 2553 dbSNP
rs1230713900 2554 dbSNP
rs1337334089 2556 dbSNP
rs1329409783 2570 dbSNP
rs1368132119 2572 dbSNP
rs1314233979 2577 dbSNP
rs1044413 2592 dbSNP
rs1374412497 2598 dbSNP
rs150363963 2627 dbSNP
rs782602811 2631 dbSNP
rs1365956877 2641 dbSNP
rs781813555 2643 dbSNP
rs1472584841 2644 dbSNP
rs782440956 2680 dbSNP
rs782684311 2681 dbSNP
rs1486046460 2682 dbSNP
rs1278121696 2688 dbSNP
rs1198979335 2693 dbSNP
rs1352531471 2699 dbSNP
rs1279968725 2715 dbSNP
rs781869771 2716 dbSNP
rs1348626132 2720 dbSNP
rs146524049 2725 dbSNP
rs1414817588 2735 dbSNP
rs1358108333 2738 dbSNP
rs1331758744 2739 dbSNP
rs1402136843 2744 dbSNP
rs1387576604 2747 dbSNP
rs1159578671 2752 dbSNP
rs1457050081 2765 dbSNP
rs1410321573 2802 dbSNP
rs1190722157 2804 dbSNP
rs1475553339 2813 dbSNP
rs1237017297 2815 dbSNP
rs782148077 2817 dbSNP
rs1185657043 2823 dbSNP
rs782381460 2838 dbSNP
rs1207804744 2865 dbSNP
rs8805 2874 dbSNP
rs1326845708 2879 dbSNP
rs1274932105 2893 dbSNP
rs1233871435 2894 dbSNP
rs1377785970 2900 dbSNP
rs1281981155 2906 dbSNP
rs12391590 2907 dbSNP
rs1326584218 2909 dbSNP
rs1319489139 2916 dbSNP
rs1434760065 2930 dbSNP
rs782224277 2941 dbSNP
rs1386947003 2954 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aauucAUUGUGGA---AGGACuuau 5'
               |:|||::|    :|||    
Target 5' ---uaUGACAUUUAAACUCUGugcc 3'
 		1 - 22
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000326624.2 | 3UTR | UAUGACAUUUAAACUCUGUGCCUACUAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
76 hsa-miR-506-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT081146 LDLR low density lipoprotein receptor 2 2
MIRT083631 PRNP prion protein 2 2
MIRT157309 IKZF2 IKAROS family zinc finger 2 2 2
MIRT172369 LONRF1 LON peptidase N-terminal domain and ring finger 1 2 2
MIRT175463 ZBTB33 zinc finger and BTB domain containing 33 2 2
MIRT178171 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 4
MIRT209107 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT254771 XRCC6 X-ray repair cross complementing 6 2 6
MIRT264771 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 4
MIRT309156 FGF2 fibroblast growth factor 2 2 6
MIRT334098 SFT2D2 SFT2 domain containing 2 2 2
MIRT386044 RORA RAR related orphan receptor A 2 2
MIRT453248 FTSJ3 FtsJ RNA methyltransferase homolog 3 2 2
MIRT455924 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT456349 OLIG3 oligodendrocyte transcription factor 3 2 8
MIRT462877 ZXDB zinc finger, X-linked, duplicated B 2 2
MIRT465017 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT466897 STMN1 stathmin 1 2 2
MIRT467919 SLC20A1 solute carrier family 20 member 1 2 2
MIRT467927 SLC16A7 solute carrier family 16 member 7 2 2
MIRT468172 SGPL1 sphingosine-1-phosphate lyase 1 2 4
MIRT483372 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT484061 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT492425 RGL2 ral guanine nucleotide dissociation stimulator like 2 2 2
MIRT495350 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT496983 DNAJC27 DnaJ heat shock protein family (Hsp40) member C27 2 2
MIRT503380 SOD2 superoxide dismutase 2 2 4
MIRT505598 SLC38A1 solute carrier family 38 member 1 2 6
MIRT507384 EN2 engrailed homeobox 2 2 6
MIRT508638 RPL23A ribosomal protein L23a 2 6
MIRT509813 SULT1B1 sulfotransferase family 1B member 1 2 4
MIRT509883 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2 4
MIRT512038 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 4
MIRT512513 BTBD19 BTB domain containing 19 2 2
MIRT513071 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT514049 AGO2 argonaute 2, RISC catalytic component 2 6
MIRT516464 RAB32 RAB32, member RAS oncogene family 2 4
MIRT523441 GPR137C G protein-coupled receptor 137C 2 4
MIRT523957 DYNLT1 dynein light chain Tctex-type 1 2 4
MIRT524143 LDHD lactate dehydrogenase D 2 4
MIRT524632 C4orf32 family with sequence similarity 241 member A 2 4
MIRT531710 TFEC transcription factor EC 2 2
MIRT532813 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT534244 SLC16A1 solute carrier family 16 member 1 2 2
MIRT534328 SHISA6 shisa family member 6 2 2
MIRT543334 UTP14C UTP14C, small subunit processome component 2 2
MIRT545944 ZBTB18 zinc finger and BTB domain containing 18 2 4
MIRT549008 CCDC6 coiled-coil domain containing 6 2 2
MIRT549226 BAZ2B bromodomain adjacent to zinc finger domain 2B 2 2
MIRT550121 RPF2 ribosome production factor 2 homolog 2 2
MIRT551421 SERTM1 serine rich and transmembrane domain containing 1 2 2
MIRT556787 KLF13 Kruppel like factor 13 2 2
MIRT561372 UBXN2B UBX domain protein 2B 2 2
MIRT561849 NPTX1 neuronal pentraxin 1 2 2
MIRT563981 SLFN11 schlafen family member 11 2 2
MIRT565747 SERTAD3 SERTA domain containing 3 2 2
MIRT569130 TMC5 transmembrane channel like 5 2 4
MIRT572714 LHX6 LIM homeobox 6 2 2
MIRT624539 BROX BRO1 domain and CAAX motif containing 2 2
MIRT637034 SPTLC3 serine palmitoyltransferase long chain base subunit 3 2 2
MIRT643213 TYW3 tRNA-yW synthesizing protein 3 homolog 2 2
MIRT646884 PLSCR1 phospholipid scramblase 1 2 2
MIRT650183 LILRA2 leukocyte immunoglobulin like receptor A2 2 2
MIRT651561 WISP1 WNT1 inducible signaling pathway protein 1 2 2
MIRT665188 HAUS5 HAUS augmin like complex subunit 5 2 2
MIRT665466 WDR13 WD repeat domain 13 2 2
MIRT668763 DDR2 discoidin domain receptor tyrosine kinase 2 2 2
MIRT680605 ZNF611 zinc finger protein 611 2 2
MIRT688564 DCAF16 DDB1 and CUL4 associated factor 16 2 2
MIRT698121 TOPBP1 DNA topoisomerase II binding protein 1 2 2
MIRT699130 SMNDC1 survival motor neuron domain containing 1 2 2
MIRT712282 PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2 2
MIRT712561 CENPO centromere protein O 2 2
MIRT715358 VCAM1 vascular cell adhesion molecule 1 2 2
MIRT720209 KCNN1 potassium calcium-activated channel subfamily N member 1 2 2
MIRT732331 MTDH metadherin 2 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-506 Glucose NULL 5793 Microarray endothelial cells 24394957 2014 up-regulated
miR-506 17beta-estradiol (E2) approved 5757 Microarray MCF-7 breast cancer cells 19528081 2009 down-regulated
miR-506 17beta-estradiol (E2) approved 5757 Microarray MCF-7AKT breast cancer cells 19528081 2009 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-506 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-506 Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-506-5p Cisplatin + Decitabine sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-506-5p Tripterygium wilfordii Hook F resistant tissue
hsa-miR-506-5p Leuprorelin/Goserelin + Bicalutamide resistant tissue (prostate cancer)

Error report submission