miRTarBase - #MIRT177407


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pre-miRNA Information
pre-miRNA hsa-mir-6768   
Genomic Coordinates chr16: 2463967 - 2464038
Description Homo sapiens miR-6768 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6768-3p
Sequence 45| CAAAGGCCACAUUCUCCUGUGCAC |68
Evidence Experimental
Experiments Meta-analysis
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN28846463 17 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs372529217 1 dbSNP
rs375499936 3 dbSNP
rs754371523 6 dbSNP
rs757893316 7 dbSNP
rs1234310587 11 dbSNP
rs369572179 12 dbSNP
rs746522005 14 dbSNP
rs768134371 15 dbSNP
rs372852875 16 dbSNP
rs572852254 17 dbSNP
rs769601549 18 dbSNP
rs773041368 20 dbSNP
rs762865317 23 dbSNP
rs770921850 24 dbSNP
Putative Targets

Gene Information
Gene Symbol ZMYND11   
Synonyms BRAM1, BS69, MRD30
Description zinc finger MYND-type containing 11
Transcript NM_006624   
Other Transcripts NM_212479   
Expression
Putative miRNA Targets on ZMYND11
3'UTR of ZMYND11
(miRNA target sites are highlighted)		 
>ZMYND11|NM_006624|3'UTR
   1 AGCTGGCCCTTCCCGGAGTCACCCCGATGATTACTCTTTTCAGACACAGCGGTTTTTGTTTCCAAGAAGCCAAAATTGTT
  81 TAGAATTTGCTTCCCATTTTGCACCAGCCTTTAAACACTTTTCGTGAAGAAATTTTGCACAGTAGTTTAAATCTTTTGTT
 161 AATGCTCCTCCGAAGTTTTTCAGGGGGTAAAAGTAACATCAGTGGAGGGTATTATTTTAAATAAATTTTAATTGAGAATT
 241 TGTTGCATTTTCAGCAAATTTTAAAACATTTTTAGGTTTTACAGAGATTTTAACCTTTAAACAACAGATCTTTAAAAAAC
 321 AGGTGAATACAAGTGAGTTTAACAAAGAAACATTTAGAATAGATCTGAATGTAAGAACTACAGAACTGTTTCAGAAATAA
 401 AACATACTACCTTGATGTGACATTTTTTTCTTAACCTTGTTGAGCTGGTTTTGTTCAGCTTAATTTACTGTTCAAAGGCA
 481 TTATCTGTTGGTCACACCAGTGGGTATATGATTGAATTTAGGGAACAGGGTTGACACAGCAGGGCTAGTCCTGCATATTT
 561 TTTCTTAAATATTTCCCAATTGTGTTTTTCATTATTTCTTTTCAATATATAACTTTTATAACAAATTATTAGCTTTGATC
 641 TTGTAGTTTAAAATTGCAGGGAACTGGGGTAATCTTTTACTGAGCTGGATCTTAGAGAAAATGAATATTTAAATTTTAAA
 721 GTTTGCACATTTCATCTTTGTCCTAACATGAGTGCTTGTAACAAAATAAACAACAAAAACAAAGCCAAAAACTACCTTTA
 801 TCCATATGTGAAATTATAGATGAGGCATACGAATTTGTTTAATGCTTCCCTTCCCTTCCCACATATCATCTCACTGCCTA
 881 TTATCTGGTGTCACCTCATGTATCGTAAGTTAATACTAAAAGAAGAGAAAGCACTTAAGTTTCACAGAAGCCGTTATGTT
 961 TGTAGTAATGGGTCATTGCCTACTAATGAACTCCATCACTGTACACAGAATGAAGAATAATGCATGTTAATTTTCTTGTA
1041 TTAAAGATGCCGTGATTTGTAAAAAGTCTGTATTTTGCGGAATGTCTGGATTAAGAAGCATTACCAATAGGAATGGATCG
1121 ATAGTTGAATAATGATTTTTTATACATAGATATATAAAATACAGCCAGGAAAACTTAAATTACTTTTCTTTTAAAATATC
1201 TCACAATTTATGTGGTATTTTTAAAGACTGATCTTAGACCAAGTCAAATTCCCATTTATCATTTAGTTATTTTTTGAGGT
1281 TAGAGAATAATTTGTACATATTTATTTAGACCTTTGATATTTATTAAAGCAATTACTCACAATGGAAGTGAAAGAATCAG
1361 GAGAAAAGCCTTTTAAAAAGTATTCTCCAGGTTTGTCAGGGTCACTCTAAAGATAAAAATGTAACTAAGTCTTCTGTGAA
1441 ATATCATCCATCTAATCTTGATGCTGTTGCAGATGGTGGTGACACAAGTTAATTGACAAACTACTGCCAAATGGTGCACA
1521 ATATTTTGTAAAAAGTACCCAGTAGCCCCATTTCATACAATGTACCTAAATTATGCAGTAACTTGGCATCATCGTTCCCT
1601 CCTTGTTGCTGTGTAATTAGTCAGTGTTGCCACAGTGTGTGGCGCTGATGGAGATGTCAGAACCGAGAACACTTAACCTT
1681 CTTTGATTGTTTTTCAAGTTTTAAGACTTCGATCCACCCCTATGAGAGCAAGTAATTGTGGAAATATTTTTGGTGTAAAA
1761 TCATTCCAGAGTATGTAATATTTAACTGATAGCTGCATGAAAGTGAGATTCGTGTTACTTTGGCTTTTCTGTCTCTGTTG
1841 ACACGGTTGCACATTTCCAAGTTACTACAGCGTGAAAACTGTGTGTTTAAAAAAAAACAAAATTAAAAAAAGAGATTGTG
1921 GCCTGGTTTTGTAAAAGTTTTAGGTAAAATTACAATTGATTGTTTTAGGAATCATTATTAAAAATTTTCTGCAAATCATA
2001 AAGCTATATCGAGGTGTTGAGCTTAGCCACTATGCACATTGTAATTATTCATTGTGGCTGTCCAGTTCTATGATGCATTC
2081 TGGCATTTTGTAAGCTGCTCTGACTAGCAATATATAGATTCATTTAATGTGTTAACATTGGTTAATAAATGTATTTAAAA
2161 AAAACTAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cacguGUCCUCUUACACCGGAAAc 5'
               ||||||||    |||||| 
Target 5' agaatCAGGAGAAAA--GCCTTTt 3'
 1353 - 1374 138.00 -16.60
2 
miRNA  3' cacgUGUCCUCUUACACCGGAaac 5'
              | | |||| ||||||||   
Target 5' taaaAAAAGAGATTGTGGCCTggt 3'
 1904 - 1927 136.00 -18.10
3 
miRNA  3' caCGUG---UC-CUCU---UAC------ACCGGAAAc 5'
            |||:   || ||||   :||      ||||:||| 
Target 5' ctGCATGAAAGTGAGATTCGTGTTACTTTGGCTTTTc 3'
 1793 - 1829 136.00 -13.94
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30662409 16 COSMIC
COSN20077031 42 COSMIC
COSN30193077 46 COSMIC
COSN30534385 50 COSMIC
COSN24303507 52 COSMIC
COSN31523649 57 COSMIC
COSN27005801 58 COSMIC
COSN30614956 74 COSMIC
COSN31489721 366 COSMIC
COSN31480251 368 COSMIC
COSN31530983 402 COSMIC
COSN31480253 431 COSMIC
COSN30163525 443 COSMIC
COSN5818577 538 COSMIC
COSN20587558 580 COSMIC
COSN31516885 599 COSMIC
COSN31520541 732 COSMIC
COSN5284283 734 COSMIC
COSN31519691 791 COSMIC
COSN30024590 813 COSMIC
COSN5284286 820 COSMIC
COSN30174057 823 COSMIC
COSN31530182 832 COSMIC
COSN26465260 871 COSMIC
COSN8639583 907 COSMIC
COSN31585314 923 COSMIC
COSN31546380 939 COSMIC
COSN31491223 984 COSMIC
COSN31591391 1079 COSMIC
COSN30175020 1081 COSMIC
COSN31551372 1165 COSMIC
COSN24101792 1261 COSMIC
COSN31571821 1262 COSMIC
COSN31543768 1295 COSMIC
COSN29163584 1582 COSMIC
COSN8639587 1655 COSMIC
COSN31607275 1742 COSMIC
COSN31569921 1744 COSMIC
COSN31579138 1815 COSMIC
COSN31541801 1845 COSMIC
COSN17402269 1890 COSMIC
COSN31545900 1898 COSMIC
COSN26643649 2012 COSMIC
COSN31515472 2122 COSMIC
COSN20092048 2157 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1287843597 4 dbSNP
rs768994205 8 dbSNP
rs773903266 9 dbSNP
rs1256526042 11 dbSNP
rs1380745692 13 dbSNP
rs761475538 14 dbSNP
rs375369771 15 dbSNP
rs1237071861 16 dbSNP
rs758504915 22 dbSNP
rs749996660 26 dbSNP
rs760260406 27 dbSNP
rs1433252133 32 dbSNP
rs766486236 41 dbSNP
rs1360238653 43 dbSNP
rs1478522342 44 dbSNP
rs753755318 46 dbSNP
rs1263211304 47 dbSNP
rs754734769 47 dbSNP
rs971592744 48 dbSNP
rs182482931 51 dbSNP
rs534128221 52 dbSNP
rs781386126 53 dbSNP
rs1033462728 59 dbSNP
rs1335816561 83 dbSNP
rs896232171 91 dbSNP
rs1012441810 105 dbSNP
rs973151867 109 dbSNP
rs1270813473 117 dbSNP
rs1435733015 121 dbSNP
rs1044720738 123 dbSNP
rs903538810 124 dbSNP
rs920274462 126 dbSNP
rs1310150306 142 dbSNP
rs1325355554 154 dbSNP
rs1376262309 154 dbSNP
rs1000505099 158 dbSNP
rs928939747 171 dbSNP
rs983334789 172 dbSNP
rs911807495 173 dbSNP
rs944591294 181 dbSNP
rs1039268037 182 dbSNP
rs1346986720 183 dbSNP
rs1376426678 183 dbSNP
rs3758506 185 dbSNP
rs1200868590 188 dbSNP
rs1237904158 191 dbSNP
rs1197029408 194 dbSNP
rs764172684 212 dbSNP
rs900609508 223 dbSNP
rs1273872352 259 dbSNP
rs187059051 260 dbSNP
rs1459748889 262 dbSNP
rs1218713577 281 dbSNP
rs1033194643 289 dbSNP
rs1200139228 293 dbSNP
rs1342875922 295 dbSNP
rs936104569 297 dbSNP
rs1456939211 299 dbSNP
rs956298805 300 dbSNP
rs1010320974 308 dbSNP
rs1329011383 318 dbSNP
rs1448602714 324 dbSNP
rs190584441 326 dbSNP
rs1333007100 327 dbSNP
rs374874943 332 dbSNP
rs1010236528 333 dbSNP
rs542442200 334 dbSNP
rs955472018 336 dbSNP
rs985973149 338 dbSNP
rs1455054950 341 dbSNP
rs1172409526 344 dbSNP
rs1380128267 344 dbSNP
rs1001733705 346 dbSNP
rs1441845953 346 dbSNP
rs1233670234 361 dbSNP
rs1427620711 363 dbSNP
rs1034948335 364 dbSNP
rs1211555148 365 dbSNP
rs1489467832 366 dbSNP
rs1306883956 372 dbSNP
rs1242050688 376 dbSNP
rs1373705264 398 dbSNP
rs1332316896 399 dbSNP
rs911329742 403 dbSNP
rs1283250335 408 dbSNP
rs1399773783 410 dbSNP
rs761728211 412 dbSNP
rs1389778701 415 dbSNP
rs962882421 416 dbSNP
rs3834409 423 dbSNP
rs973568262 423 dbSNP
rs1332815343 427 dbSNP
rs1233868254 439 dbSNP
rs962676289 448 dbSNP
rs375712698 461 dbSNP
rs1360443990 463 dbSNP
rs1157311193 468 dbSNP
rs1402817802 471 dbSNP
rs1409107155 480 dbSNP
rs1181526081 481 dbSNP
rs1282476796 488 dbSNP
rs1321160625 492 dbSNP
rs974080041 494 dbSNP
rs1188733037 500 dbSNP
rs918465947 500 dbSNP
rs1487962657 501 dbSNP
rs556102305 522 dbSNP
rs1283809020 524 dbSNP
rs929914713 529 dbSNP
rs991999442 536 dbSNP
rs1317321084 538 dbSNP
rs1288833499 540 dbSNP
rs950427226 553 dbSNP
rs917773608 554 dbSNP
rs1398852037 555 dbSNP
rs947813660 556 dbSNP
rs572728265 570 dbSNP
rs776758441 571 dbSNP
rs1338294175 576 dbSNP
rs911838736 580 dbSNP
rs966339697 585 dbSNP
rs1433449598 587 dbSNP
rs1164486414 598 dbSNP
rs1346198841 598 dbSNP
rs1403873595 599 dbSNP
rs1420291096 605 dbSNP
rs1193613473 622 dbSNP
rs1477546491 630 dbSNP
rs1045192311 632 dbSNP
rs181818045 639 dbSNP
rs1188243318 643 dbSNP
rs1486136912 644 dbSNP
rs147376275 658 dbSNP
rs935817416 660 dbSNP
rs1323220346 662 dbSNP
rs1054582108 674 dbSNP
rs1198767862 677 dbSNP
rs533156913 688 dbSNP
rs1279502294 692 dbSNP
rs1052052928 706 dbSNP
rs1479020901 707 dbSNP
rs946057682 708 dbSNP
rs892039927 714 dbSNP
rs1010472997 719 dbSNP
rs767368083 729 dbSNP
rs1460642437 742 dbSNP
rs1465262849 744 dbSNP
rs760009072 744 dbSNP
rs1002205909 748 dbSNP
rs1429117689 749 dbSNP
rs1424377951 757 dbSNP
rs750061528 758 dbSNP
rs1189340013 759 dbSNP
rs879021387 768 dbSNP
rs1056017432 772 dbSNP
rs1386219459 774 dbSNP
rs1197665019 775 dbSNP
rs1456154632 775 dbSNP
rs1302482936 777 dbSNP
rs1029812011 783 dbSNP
rs1227516870 784 dbSNP
rs891263537 794 dbSNP
rs1007071211 801 dbSNP
rs1401645672 803 dbSNP
rs1018739518 806 dbSNP
rs1373690273 825 dbSNP
rs1446386269 829 dbSNP
rs112037913 831 dbSNP
rs760312613 832 dbSNP
rs1358597771 837 dbSNP
rs1173901484 845 dbSNP
rs1455505002 845 dbSNP
rs563626850 848 dbSNP
rs1395508335 854 dbSNP
rs1177757287 859 dbSNP
rs1437512112 861 dbSNP
rs950459504 863 dbSNP
rs1025687313 864 dbSNP
rs765807049 865 dbSNP
rs185845198 866 dbSNP
rs1221026231 867 dbSNP
rs547940877 881 dbSNP
rs992510578 901 dbSNP
rs965714216 905 dbSNP
rs753448544 906 dbSNP
rs190256332 910 dbSNP
rs1375068341 911 dbSNP
rs369255949 933 dbSNP
rs1262910309 935 dbSNP
rs527554832 938 dbSNP
rs1301139656 939 dbSNP
rs1436563938 952 dbSNP
rs980638213 953 dbSNP
rs957464557 954 dbSNP
rs1417649032 958 dbSNP
rs1365279211 962 dbSNP
rs924994218 972 dbSNP
rs1182121204 987 dbSNP
rs936463699 1000 dbSNP
rs913341973 1001 dbSNP
rs1485673425 1005 dbSNP
rs1281680515 1015 dbSNP
rs1216461942 1020 dbSNP
rs1349024197 1021 dbSNP
rs1262828656 1026 dbSNP
rs1052038284 1030 dbSNP
rs1240085860 1031 dbSNP
rs1321332622 1034 dbSNP
rs1457486581 1041 dbSNP
rs753212467 1046 dbSNP
rs553378096 1049 dbSNP
rs752022388 1052 dbSNP
rs1398031866 1060 dbSNP
rs928634189 1061 dbSNP
rs1158908406 1063 dbSNP
rs937318177 1066 dbSNP
rs753787868 1069 dbSNP
rs1166574922 1070 dbSNP
rs1475260782 1071 dbSNP
rs1051755008 1074 dbSNP
rs1193624451 1079 dbSNP
rs570462703 1080 dbSNP
rs1421415222 1085 dbSNP
rs1056489340 1086 dbSNP
rs1356003826 1095 dbSNP
rs539043210 1097 dbSNP
rs1361004452 1099 dbSNP
rs995662091 1109 dbSNP
rs1335586632 1116 dbSNP
rs1047200765 1118 dbSNP
rs1018481660 1121 dbSNP
rs1225216083 1135 dbSNP
rs1004603930 1136 dbSNP
rs887254870 1136 dbSNP
rs1391952283 1143 dbSNP
rs1314461031 1145 dbSNP
rs1327537635 1146 dbSNP
rs898571682 1146 dbSNP
rs1461610686 1147 dbSNP
rs1018617675 1150 dbSNP
rs1340663398 1152 dbSNP
rs556273883 1154 dbSNP
rs966105774 1160 dbSNP
rs1375288028 1161 dbSNP
rs995846971 1163 dbSNP
rs1029351347 1168 dbSNP
rs1251484661 1175 dbSNP
rs957290006 1176 dbSNP
rs995621118 1179 dbSNP
rs1194148262 1180 dbSNP
rs1257571642 1180 dbSNP
rs990041158 1183 dbSNP
rs757641318 1192 dbSNP
rs569644399 1196 dbSNP
rs370220813 1205 dbSNP
rs1232389697 1207 dbSNP
rs1312253863 1209 dbSNP
rs1020141691 1212 dbSNP
rs967168570 1216 dbSNP
rs1399085548 1217 dbSNP
rs1326365911 1244 dbSNP
rs182388854 1247 dbSNP
rs928733782 1249 dbSNP
rs1180247079 1261 dbSNP
rs1477973072 1261 dbSNP
rs1238773224 1262 dbSNP
rs1356543707 1263 dbSNP
rs1393715480 1263 dbSNP
rs1454922029 1265 dbSNP
rs937372620 1271 dbSNP
rs1179853083 1281 dbSNP
rs1025634875 1285 dbSNP
rs137970569 1295 dbSNP
rs1199849911 1299 dbSNP
rs1260584501 1301 dbSNP
rs1443953411 1305 dbSNP
rs1282281550 1310 dbSNP
rs992186921 1318 dbSNP
rs1375795786 1321 dbSNP
rs555967219 1321 dbSNP
rs1202489408 1333 dbSNP
rs1047276923 1337 dbSNP
rs1335878261 1341 dbSNP
rs1327624938 1349 dbSNP
rs1374170076 1354 dbSNP
rs1176004861 1361 dbSNP
rs1444199346 1362 dbSNP
rs1011000296 1364 dbSNP
rs1175740366 1371 dbSNP
rs944173031 1388 dbSNP
rs1233577546 1391 dbSNP
rs763430526 1413 dbSNP
rs1382232752 1417 dbSNP
rs1040559364 1421 dbSNP
rs1025278113 1422 dbSNP
rs1484693671 1422 dbSNP
rs1259546040 1426 dbSNP
rs901577751 1431 dbSNP
rs1352759108 1434 dbSNP
rs1281846535 1444 dbSNP
rs969335044 1446 dbSNP
rs996266714 1451 dbSNP
rs764491304 1453 dbSNP
rs1412394491 1484 dbSNP
rs925146333 1492 dbSNP
rs1356754577 1539 dbSNP
rs1344473907 1544 dbSNP
rs957765065 1547 dbSNP
rs572790948 1550 dbSNP
rs987826165 1551 dbSNP
rs1157352544 1554 dbSNP
rs1402727479 1561 dbSNP
rs1028675443 1565 dbSNP
rs1164409163 1566 dbSNP
rs1474278963 1567 dbSNP
rs913665949 1569 dbSNP
rs1304339481 1577 dbSNP
rs1420065832 1586 dbSNP
rs1188625640 1591 dbSNP
rs932945364 1594 dbSNP
rs1051438982 1595 dbSNP
rs912801829 1599 dbSNP
rs1231026352 1603 dbSNP
rs1336356976 1614 dbSNP
rs1020174322 1619 dbSNP
rs759108898 1623 dbSNP
rs1361857608 1631 dbSNP
rs1334203609 1632 dbSNP
rs942998014 1636 dbSNP
rs541778558 1644 dbSNP
rs1039885235 1645 dbSNP
rs1460045061 1650 dbSNP
rs958800039 1656 dbSNP
rs898690846 1665 dbSNP
rs995694532 1666 dbSNP
rs576975361 1668 dbSNP
rs1240171874 1675 dbSNP
rs1306945811 1678 dbSNP
rs1188144757 1679 dbSNP
rs919952861 1679 dbSNP
rs1475633346 1683 dbSNP
rs931281946 1684 dbSNP
rs1211490838 1686 dbSNP
rs1235938002 1687 dbSNP
rs1256929138 1698 dbSNP
rs1461081695 1699 dbSNP
rs1202004177 1702 dbSNP
rs1047151915 1706 dbSNP
rs1240184364 1713 dbSNP
rs1458280546 1717 dbSNP
rs887200607 1724 dbSNP
rs1013965985 1739 dbSNP
rs1025015622 1751 dbSNP
rs558144744 1752 dbSNP
rs1002150915 1756 dbSNP
rs578005030 1758 dbSNP
rs1407221122 1772 dbSNP
rs1305197932 1789 dbSNP
rs908799176 1794 dbSNP
rs944236753 1799 dbSNP
rs1363144798 1812 dbSNP
rs1439057439 1813 dbSNP
rs543443610 1813 dbSNP
rs1032239021 1822 dbSNP
rs899974616 1825 dbSNP
rs1461561135 1836 dbSNP
rs1352791351 1838 dbSNP
rs185084569 1846 dbSNP
rs1410440167 1858 dbSNP
rs756932821 1866 dbSNP
rs1394311780 1868 dbSNP
rs549088227 1869 dbSNP
rs1253254415 1870 dbSNP
rs1050563866 1871 dbSNP
rs780566839 1872 dbSNP
rs780629181 1873 dbSNP
rs552876250 1880 dbSNP
rs892809259 1881 dbSNP
rs1011244664 1889 dbSNP
rs1020247487 1889 dbSNP
rs1373577265 1889 dbSNP
rs529301481 1890 dbSNP
rs987533243 1894 dbSNP
rs1391004232 1895 dbSNP
rs541645519 1896 dbSNP
rs1297072754 1898 dbSNP
rs1035547306 1899 dbSNP
rs561512276 1899 dbSNP
rs1171617331 1905 dbSNP
rs958756605 1910 dbSNP
rs1395411692 1911 dbSNP
rs1039957415 1913 dbSNP
rs920190598 1915 dbSNP
rs1252123369 1917 dbSNP
rs1027446623 1922 dbSNP
rs1485020906 1933 dbSNP
rs1302492101 1934 dbSNP
rs1257455126 1939 dbSNP
rs1209300225 1955 dbSNP
rs1323279513 1955 dbSNP
rs1350547797 1956 dbSNP
rs527469840 1957 dbSNP
rs952756175 1961 dbSNP
rs190666088 1970 dbSNP
rs1318834344 1971 dbSNP
rs1311026635 1972 dbSNP
rs965616789 1974 dbSNP
rs373126909 1976 dbSNP
rs1479656152 1980 dbSNP
rs1288058841 1985 dbSNP
rs1451264741 1987 dbSNP
rs564222612 1988 dbSNP
rs1159305543 1991 dbSNP
rs977378978 1999 dbSNP
rs1414974717 2006 dbSNP
rs1393871298 2007 dbSNP
rs1486929713 2008 dbSNP
rs41285615 2010 dbSNP
rs865932013 2011 dbSNP
rs1013705026 2015 dbSNP
rs1173943700 2016 dbSNP
rs1425375416 2020 dbSNP
rs1229202239 2026 dbSNP
rs1334309346 2028 dbSNP
rs1291487012 2029 dbSNP
rs780115038 2033 dbSNP
rs1169200536 2034 dbSNP
rs1352252069 2038 dbSNP
rs749417126 2040 dbSNP
rs1002628030 2041 dbSNP
rs747463169 2045 dbSNP
rs1289125139 2047 dbSNP
rs1032185041 2049 dbSNP
rs1458933078 2054 dbSNP
rs957950069 2055 dbSNP
rs184108341 2061 dbSNP
rs569751345 2062 dbSNP
rs1020775823 2070 dbSNP
rs535506798 2071 dbSNP
rs549082582 2091 dbSNP
rs1345380086 2094 dbSNP
rs987264987 2098 dbSNP
rs1403533747 2114 dbSNP
rs1264263954 2136 dbSNP
rs1041387096 2157 dbSNP
rs947065628 2157 dbSNP
rs566303470 2158 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000381591.1 | 3UTR | CUUCCCAUUUUGCACCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
95 hsa-miR-6768-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT060980 LAMC1 laminin subunit gamma 1 2 2
MIRT145633 LASP1 LIM and SH3 protein 1 2 2
MIRT161065 CDV3 CDV3 homolog 2 2
MIRT161171 SLC25A36 solute carrier family 25 member 36 2 2
MIRT177407 ZMYND11 zinc finger MYND-type containing 11 2 2
MIRT262237 WAC WW domain containing adaptor with coiled-coil 2 2
MIRT300236 INO80D INO80 complex subunit D 2 2
MIRT373993 PEBP1 phosphatidylethanolamine binding protein 1 2 4
MIRT379949 CRY2 cryptochrome circadian clock 2 2 2
MIRT405244 ADIPOR2 adiponectin receptor 2 2 2
MIRT441622 ROCK1 Rho associated coiled-coil containing protein kinase 1 2 6
MIRT441807 NOC3L NOC3 like DNA replication regulator 2 2
MIRT442007 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT442254 DCTN5 dynactin subunit 5 2 2
MIRT442413 LIMD1 LIM domains containing 1 2 2
MIRT442741 SERINC5 serine incorporator 5 2 2
MIRT442796 CEP170 centrosomal protein 170 2 2
MIRT443332 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT443602 ZNF91 zinc finger protein 91 2 2
MIRT443695 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT443749 ELL2 elongation factor for RNA polymerase II 2 2 2
MIRT446376 THSD4 thrombospondin type 1 domain containing 4 2 2
MIRT452491 BANK1 B-cell scaffold protein with ankyrin repeats 1 2 16
MIRT456028 PSMA7 proteasome subunit alpha 7 2 2
MIRT461191 TRIP4 thyroid hormone receptor interactor 4 2 16
MIRT464498 UCK2 uridine-cytidine kinase 2 2 2
MIRT466640 TAOK1 TAO kinase 1 2 16
MIRT466703 TAF13 TATA-box binding protein associated factor 13 2 4
MIRT467765 SLC30A7 solute carrier family 30 member 7 2 2
MIRT469973 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT470539 COASY Coenzyme A synthase 2 2
MIRT474827 KIAA0226 RUN and cysteine rich domain containing beclin 1 interacting protein 2 2
MIRT475961 GXYLT1 glucoside xylosyltransferase 1 2 4
MIRT476459 GBA2 glucosylceramidase beta 2 2 2
MIRT477658 EFNA1 ephrin A1 2 2
MIRT485320 MZT1 mitotic spindle organizing protein 1 2 4
MIRT485656 CYP1B1 cytochrome P450 family 1 subfamily B member 1 2 2
MIRT494145 CTC1 CST telomere replication complex component 1 2 10
MIRT495127 CXorf67 chromosome X open reading frame 67 2 2
MIRT498279 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT498432 DDX39A DExD-box helicase 39A 2 2
MIRT498853 LITAF lipopolysaccharide induced TNF factor 2 4
MIRT499661 SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2 2
MIRT502927 CDC42SE1 CDC42 small effector 1 2 4
MIRT503758 CEP19 centrosomal protein 19 2 6
MIRT507753 CERS2 ceramide synthase 2 2 4
MIRT507893 CAMSAP2 calmodulin regulated spectrin associated protein family member 2 2 4
MIRT510091 PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2 8
MIRT527065 PPP6R1 protein phosphatase 6 regulatory subunit 1 2 2
MIRT530314 TNFRSF10D TNF receptor superfamily member 10d 2 2
MIRT530702 P2RY1 purinergic receptor P2Y1 2 2
MIRT532378 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT532969 ZNF148 zinc finger protein 148 2 2
MIRT533958 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D 2 2
MIRT535186 PLEKHA8 pleckstrin homology domain containing A8 2 2
MIRT538751 CADM1 cell adhesion molecule 1 2 2
MIRT539473 ADARB2 adenosine deaminase, RNA specific B2 (inactive) 2 2
MIRT543858 APIP APAF1 interacting protein 2 2
MIRT558802 CDON cell adhesion associated, oncogene regulated 2 2
MIRT560208 AK4 adenylate kinase 4 2 2
MIRT560318 EFHD2 EF-hand domain family member D2 2 2
MIRT560439 GOLGA7B golgin A7 family member B 2 2
MIRT560846 SUV39H2 suppressor of variegation 3-9 homolog 2 2 2
MIRT562787 LIMA1 LIM domain and actin binding 1 2 2
MIRT563476 POLE3 DNA polymerase epsilon 3, accessory subunit 2 2
MIRT563829 RIPK4 receptor interacting serine/threonine kinase 4 2 2
MIRT563996 SLFN11 schlafen family member 11 2 2
MIRT564596 ZNF791 zinc finger protein 791 2 2
MIRT565442 SURF4 surfeit 4 2 2
MIRT566020 RHOA ras homolog family member A 2 2
MIRT566185 PTPN14 protein tyrosine phosphatase, non-receptor type 14 2 2
MIRT567643 FAM160A1 family with sequence similarity 160 member A1 2 2
MIRT568484 ARL5B ADP ribosylation factor like GTPase 5B 2 2
MIRT568553 AKT2 AKT serine/threonine kinase 2 2 2
MIRT613420 XRCC3 X-ray repair cross complementing 3 2 2
MIRT613638 ARHGAP35 Rho GTPase activating protein 35 2 2
MIRT614841 POU2F2 POU class 2 homeobox 2 2 2
MIRT630143 ZFYVE9 zinc finger FYVE-type containing 9 2 2
MIRT634123 ZMYM1 zinc finger MYM-type containing 1 2 4
MIRT641841 TCF7L2 transcription factor 7 like 2 2 2
MIRT647123 ZNF446 zinc finger protein 446 2 2
MIRT647968 FBXO31 F-box protein 31 2 2
MIRT658186 FBXO9 F-box protein 9 2 2
MIRT659097 DENR density regulated re-initiation and release factor 2 2
MIRT668980 CLCN3 chloride voltage-gated channel 3 2 2
MIRT670351 C1orf106 chromosome 1 open reading frame 106 2 4
MIRT671826 TRPM6 transient receptor potential cation channel subfamily M member 6 2 2
MIRT695610 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT697722 USP8 ubiquitin specific peptidase 8 2 2
MIRT700069 RPL14 ribosomal protein L14 2 2
MIRT708474 MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2 2
MIRT717001 ARL6IP4 ADP ribosylation factor like GTPase 6 interacting protein 4 2 2
MIRT719591 TFCP2L1 transcription factor CP2 like 1 2 2
MIRT722026 CBY3 chibby family member 3 2 2
MIRT722901 LRRC20 leucine rich repeat containing 20 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6768 Ceritinib 57379345 NSC776422 approved sensitive High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-6768 Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-mir-6768 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-mir-6768 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-6768-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-6768-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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