miRTarBase - #MIRT178171


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pre-miRNA Information
pre-miRNA hsa-mir-506   
Genomic Coordinates chrX: 147230720 - 147230843
Synonyms MIRN506, hsa-mir-506, MIR506
Description Homo sapiens miR-506 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-506-5p
Sequence 35| UAUUCAGGAAGGUGUUACUUAA |56
Evidence Not_experimental
Experiments
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs782463365 2 dbSNP
rs781802841 18 dbSNP
rs782722056 21 dbSNP
rs782039395 22 dbSNP
Putative Targets

Gene Information
Gene Symbol EIF5AL1   
Synonyms EIF5AP1, bA342M3.3
Description eukaryotic translation initiation factor 5A-like 1
Transcript NM_001099692   
Expression
Putative miRNA Targets on EIF5AL1
3'UTR of EIF5AL1
(miRNA target sites are highlighted)		 
>EIF5AL1|NM_001099692|3'UTR
   1 CTGGCTCCCAAGGTGGCAGTGGTGGCAGCAGTGATCCTCCGAACCTGCAGAGGCCCCCTCCCCCAGCCTGGCCTGGCTCT
  81 GGCCTGGTCCTAGGTTGGACTCCTCCTACACAATTTATTTGACGTTTTATTTTGGTTTTCCCCACCCCCTCAATCTGTCA
 161 GGGAGCCCCTGCCCTTCACCTAGCTCCCTTGGCCAGGAGCGAGCGAAGCCATGGCCTTGGTGAAGCTGCCCTCCTCTTCT
 241 CCCCTCACACTACAGCCCTGGTGGGGGAGAAGGGGGTGGGTGCTGCTTGTGGTTTAGTCTTTTTTTTTTTTTTAAATTCA
 321 ATCTGGAATCAGAAAGCGGTGGATTCTGGCAAATGGTCCTTGTGCCCTCCCCACTCATCCTTGGTCTGGTCCCCTGTTGC
 401 CCATAGCCCTTTACCCTGAGCACCACCCAACAGACTGGGGACCAGCCCCCTCGCCTGCCTGTGTCTCTCCCCAAACCCCT
 481 TTAGATGGGGAGGGAAGAAGAGGAGAGGGGAGGGGACCTGCCCCCTCCTCAGGCATCTGGGAAGGGCCTGCCCCCATGGG
 561 CTTTACCCTTCCCTGCGGGCTCTCTCCCCGACACATTTGTTAAAATCAAACCTGAATAAAACTACAAGTTTAATATGAAA
 641 AAAAAAAAAAAAGAAAGAAAGACGTGTAAAATGCCAAGAACTCTAGGAAACAGGGACAAAAACACTTCAAAGAGAAAGTT
 721 CATGCACTTGTTTCTGACCACCCAGGGCACCCTTCAGCACACGCTGTCTGGAGTGGCCTGAAGCAAGGAGTGTCTTGTGA
 801 GGTGCAGAGGATGCAATGGGAGCAGGGTCCTGTCCCCACCCTAAAGGAGTTCACAGTTTAACGCAAATGAGAAGCCAGTG
 881 AGGACATCACTACTCCTGCTGTGAACTTGGGAACTAGAAACACAAAACCTGAGTCTGGAGGGAAGCTAAGGAAGCATTCT
 961 GCTCTGGAGTAGACATGAGTGCGTGTGAAGCTTCTGATCTCCCATGAGAGCAATGGGGACATGGGGCAGAATCTAAAACC
1041 CATGACTGAAAGCACCAAATTGCTAAAATGGCAATAAAGAGACATGAGGCCAAGATGGAGAAGAAGGAACCCAGGACGAG
1121 GGTCAGCCTCACATTTGGGGCTCATTTCCCTCAGTTTCCTCACTGAATTTCAGAAGGGACTAACTGAGATGCAAAGAAGC
1201 AGAGCAGCTTTTGCACCATGTGGAGGACTAGATGGAAAACAAGTAGACTGAGGGTCTGCTAGTGAAGGTGACCCCTACTG
1281 AAGTCCACTGGCTTTGGTTGGGACCCAGAAGAGTCACACGCCAGGAATAGAGGTGGACAGGAAACACCCTGACTTTTGTA
1361 GGGACTGAACCTCACTGATAACCTCAATTGCGGATGGTATGGAGGGTGTCTAGGTGTGCTAGGACCCCTGCCCATTCCCC
1441 AGAAATAGACTCCCATCTTTTCTACAGCAAGATAACGTGCTAGTAGGCCTCAATTCATTGCTAAATATTTTTAACGAGTG
1521 TCTTACATTTAGCCAAAAAGACTAGTCATGTGGCAGGAAAAATACAATGTCATATGACCAAAAGCTAAAAGACTGTGAAA
1601 ATGAATCCAGAGGTGACCCAAGCATTGAATTTAACAATGCCAGTACCTGGACCTCCGCTTGCCCCTAAAACATTACAATC
1681 AAGAATGTAGGAAGGGAAAGGAAACACGAAGATTAATCAAGCAGGAAGGACAAGCTCAGTTTTGCACCCACTGAATTTGC
1761 CACAAATATTGTGGAAAATATTCTCGGGGACATTGCAGTTGTCTACTTTGGTTGGCACATGGTTCATACAACAGTGTTTG
1841 TGTCAGTGAACATCTTACTCTTCCTCGGCAGTCTTTCTTTGCCCAGAGATTTCGCAATGACTGTTGACCTTCATCATCAC
1921 CTTTTGGACTTTGGCTTGCACTTTAGCTTCTGTAGATCTCCATGATGTAAAGAAGTATTTTAGGTCCATTTTAATTCCTG
2001 CAAAGGATAAAATCCTTCTATTTGTGTGCATATAAGTGGACCTGAGCCCTTGGTTAGGGTGTAGAGAGGAGAAGGGGAGA
2081 AACCTGAGGGCCAGAAGCTGTTCTTTCCCTTAAAAGGGCAAACTCATTTCCACACTATGGGGACTCTGACAGATAGCATA
2161 CCTTCCTGTCTATGGCTATTGGACCTGCAGGCTTTCCCCTGTAAATCCGTGTTCTGTCATTGACATTTTGTGACTGTAAG
2241 ACAGACTTGAGATAAGACATCTAGAAAACAATAATTGAACAATGATGTGAATATATTTCACACAACTGAACTGTACATTT
2321 CAACAAGGTTAAGATGGTAATTATCACGTTATACATTTTTTACCGCAGGTTAAAATGTTTCACAGGTTGAAAGGAAAGCA
2401 ACTACCTTCAGTTCTCTGAGTTCAAGAATTTGTAACATTTCACCCCCTGCTCCTTCCTGATCTTCTGTGGAGCATCTTTT
2481 TTCCATCCATGCTCTACTCAGAGCCCACTTTCCCTTCCCTGACACCAGCTTCACTGAGGCTGGTTGGAACCTAACACAAA
2561 ACATTCTCAGTAATGACTGAATTCCCACAAAGAATTCCATATAGACTGCATATGAGTTGAATCTTCTAAGACATGAAATA
2641 TTTGTTCTCTTCTTGGCTAATATGCAATGCAAATCCTGTTGCAGATGTACGTCATATACCTCTGAAATTCCTGATGTATT
2721 CAATGAAATAACATCTTTAAAGTTCTGTGTAGAATGTTTTTTTTCTGATTTCTTCACATACGATAGAAAAAAAAACCCAA
2801 AAAAACATGTACTAGGATTTCAATAGAAGCAATGGGTGATCTAAAAAGATGAAAGAGCAACCGCATGCGCCCTACAGCTA
2881 CCGCTAGATTTTATGGGGAAAGCAGCTGGCCCAGTTTGCAGCTAGGAGAAATGTCAAACACATGAAGAAATGAGAAGCAA
2961 AGAAAAACCATGAGGCATGAACATTTCATGGCAATCACGATGTCCTGGTTTGTGAGATAATGGGATAGAGGAGTAGAAAA
3041 CAAGGAGAAAGATGAGAAGGTACAAAGTGGTTCAAGTCAAACAGCTCAACTGAACTTTTCTTAATGGAATATTTAAAAAG
3121 TGGTACATTAAAAAACTTCCCCCAGTTCACATCAAAAATTCTCTCTTCAGGACTAAGTTGGGTAGAGACTGTTCAATGTG
3201 CCTAGATATCTTCAGAACTTATATATTTTCTGTTTTCTACGTATGTTGAAGGGCAGTGCCAAATGATGTGTAATTATCTA
3281 GGTTGTAAAAATAAAACATACTCCCCCTTCCCTTGAGGATAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aauucAUUGUGG-AAGGACUUAu 5'
               ||| |:|   ||||||| 
Target 5' tttgtTAAAATCAAACCTGAATa 3'
 596 - 618 149.00 -10.00
2 
miRNA  3' aauUCAUUGUG-GAAGGACUUAu 5'
             || |||||    |||||:| 
Target 5' actAGAAACACAAAACCTGAGTc 3'
 913 - 935 139.00 -13.50
3 
miRNA  3' aaUUCAUUG-UGGAA------GGACUUAu 5'
            ||| ||| |||||      :||||:| 
Target 5' gaAAGCAACTACCTTCAGTTCTCTGAGTt 3'
 2394 - 2422 134.00 -14.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN15623903 9 COSMIC
COSN19695423 12 COSMIC
COSN28596743 19 COSMIC
COSN30127616 40 COSMIC
COSN28600693 41 COSMIC
COSN30134685 42 COSMIC
COSN30513996 66 COSMIC
COSN30451557 69 COSMIC
COSN31491314 77 COSMIC
COSN30174783 80 COSMIC
COSN30530634 82 COSMIC
COSN15623904 93 COSMIC
COSN30460478 104 COSMIC
COSN26601854 108 COSMIC
COSN31538520 125 COSMIC
COSN23012268 140 COSMIC
COSN31532807 150 COSMIC
COSN28642116 216 COSMIC
COSN15623905 223 COSMIC
COSN24303437 279 COSMIC
COSN31561620 282 COSMIC
COSN19661387 313 COSMIC
COSN8721944 314 COSMIC
COSN17251091 338 COSMIC
COSN8189997 339 COSMIC
COSN31578946 360 COSMIC
COSN31490073 364 COSMIC
COSN26569189 382 COSMIC
COSN31488303 468 COSMIC
COSN31536788 471 COSMIC
COSN31551690 534 COSMIC
COSN31562843 577 COSMIC
COSN31593692 578 COSMIC
COSN20092131 590 COSMIC
COSN16669840 595 COSMIC
COSN28649496 621 COSMIC
COSN31568558 629 COSMIC
COSN23961180 650 COSMIC
COSN28826693 654 COSMIC
COSN26642068 688 COSMIC
COSN26506599 726 COSMIC
COSN30526632 727 COSMIC
COSN15623906 735 COSMIC
COSN30172996 759 COSMIC
COSN16914468 763 COSMIC
COSN30529886 765 COSMIC
COSN30540981 765 COSMIC
COSN24303349 864 COSMIC
COSN8721945 884 COSMIC
COSN28712219 886 COSMIC
COSN30122085 901 COSMIC
COSN26559597 934 COSMIC
COSN23972520 935 COSMIC
COSN30136825 939 COSMIC
COSN30121727 961 COSMIC
COSN15623907 982 COSMIC
COSN26571205 1010 COSMIC
COSN30537294 1011 COSMIC
COSN30545028 1017 COSMIC
COSN30530970 1044 COSMIC
COSN8189998 1045 COSMIC
COSN30133024 1086 COSMIC
COSN15623908 1099 COSMIC
COSN28669077 1118 COSMIC
COSN8640533 1118 COSMIC
COSN32128896 1153 COSMIC
COSN1501705 1193 COSMIC
COSN30130415 1238 COSMIC
COSN30539276 1251 COSMIC
COSN31608411 1321 COSMIC
COSN15623909 1403 COSMIC
COSN15623910 1439 COSMIC
COSN28529472 1465 COSMIC
COSN30114571 1467 COSMIC
COSN30142005 1472 COSMIC
COSN7070026 1497 COSMIC
COSN28740048 1545 COSMIC
COSN8640534 1545 COSMIC
COSN31960506 1579 COSMIC
COSN31537904 1591 COSMIC
COSN30513667 1592 COSMIC
COSN15623911 1604 COSMIC
COSN26678464 1604 COSMIC
COSN15623912 1656 COSMIC
COSN31530990 1675 COSMIC
COSN30120911 1709 COSMIC
COSN31524143 1803 COSMIC
COSN30136578 1838 COSMIC
COSN30117745 1851 COSMIC
COSN15623913 1889 COSMIC
COSN28749126 1894 COSMIC
COSN23012269 1926 COSMIC
COSN31601853 1956 COSMIC
COSN28766006 1969 COSMIC
COSN7070027 1969 COSMIC
COSN31578140 1973 COSMIC
COSN31573234 1984 COSMIC
COSN31576572 1984 COSMIC
COSN15623914 1987 COSMIC
COSN30176963 2014 COSMIC
COSN31530450 2036 COSMIC
COSN30126077 2047 COSMIC
COSN28758990 2141 COSMIC
COSN30539821 2186 COSMIC
COSN26678027 2212 COSMIC
COSN31519684 2252 COSMIC
COSN30111883 2265 COSMIC
COSN6605693 2285 COSMIC
COSN16599748 2348 COSMIC
COSN31594569 2362 COSMIC
COSN31482863 2382 COSMIC
COSN15623915 2394 COSMIC
COSN30112127 2427 COSMIC
COSN5291199 2545 COSMIC
COSN19344901 2574 COSMIC
COSN31609589 2593 COSMIC
COSN4695240 2627 COSMIC
COSN30119567 2670 COSMIC
COSN30137394 2685 COSMIC
COSN30130199 2711 COSMIC
COSN30143061 2752 COSMIC
COSN20107305 2765 COSMIC
COSN28637219 2782 COSMIC
COSN31490466 2782 COSMIC
COSN29467764 2783 COSMIC
COSN1123067 2796 COSMIC
COSN25448511 2796 COSMIC
COSN30128885 2796 COSMIC
COSN15623916 2797 COSMIC
COSN30133155 2801 COSMIC
COSN23012270 2806 COSMIC
COSN5291200 2832 COSMIC
COSN10073304 2856 COSMIC
COSN28823440 2869 COSMIC
COSN30122755 2870 COSMIC
COSN28714293 2874 COSMIC
COSN31570881 2975 COSMIC
COSN28633274 2980 COSMIC
COSN30120012 3000 COSMIC
COSN5884787 3052 COSMIC
COSN15623917 3093 COSMIC
COSN26636962 3146 COSMIC
COSN28533783 3146 COSMIC
COSN30142505 3157 COSMIC
COSN15623918 3162 COSMIC
COSN7070028 3241 COSMIC
COSN31483438 3242 COSMIC
COSN30543386 3256 COSMIC
COSN28776385 3307 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1180105632 5 dbSNP
rs1428754649 6 dbSNP
rs1409566249 8 dbSNP
rs199829110 12 dbSNP
rs774001523 14 dbSNP
rs745741524 15 dbSNP
rs771778567 17 dbSNP
rs1037749236 19 dbSNP
rs776787386 20 dbSNP
rs375383701 24 dbSNP
rs1286693383 26 dbSNP
rs1448172417 29 dbSNP
rs769838158 31 dbSNP
rs1241089952 37 dbSNP
rs1488640720 39 dbSNP
rs530848190 41 dbSNP
rs763440123 42 dbSNP
rs1454191756 46 dbSNP
rs1049562635 48 dbSNP
rs766980301 50 dbSNP
rs1313266371 53 dbSNP
rs1196515331 54 dbSNP
rs1241469786 54 dbSNP
rs551038176 65 dbSNP
rs1389720218 68 dbSNP
rs890984743 68 dbSNP
rs1303680756 69 dbSNP
rs1423829992 71 dbSNP
rs1363498359 75 dbSNP
rs1160164208 86 dbSNP
rs1470327982 94 dbSNP
rs376353382 96 dbSNP
rs1179116137 102 dbSNP
rs1434370034 103 dbSNP
rs1223865317 105 dbSNP
rs561253312 111 dbSNP
rs1290053038 113 dbSNP
rs1207212274 118 dbSNP
rs1351732335 120 dbSNP
rs1467322394 123 dbSNP
rs1237060746 124 dbSNP
rs1347450269 125 dbSNP
rs530285988 143 dbSNP
rs1254058515 146 dbSNP
rs1449285658 147 dbSNP
rs1363598471 149 dbSNP
rs1320074984 154 dbSNP
rs181568144 159 dbSNP
rs891576736 163 dbSNP
rs1011654746 167 dbSNP
rs1467186292 168 dbSNP
rs1021313536 170 dbSNP
rs566778560 176 dbSNP
rs970701228 182 dbSNP
rs1480408029 187 dbSNP
rs1267351525 193 dbSNP
rs1001752271 194 dbSNP
rs1375348555 196 dbSNP
rs1447934665 201 dbSNP
rs1462048584 202 dbSNP
rs1162133523 205 dbSNP
rs2475361 206 dbSNP
rs150231945 212 dbSNP
rs1271825862 213 dbSNP
rs1035795796 215 dbSNP
rs1250784 216 dbSNP
rs1364150396 217 dbSNP
rs1454253292 220 dbSNP
rs568822142 222 dbSNP
rs1175146151 229 dbSNP
rs907950199 232 dbSNP
rs963520912 235 dbSNP
rs561775528 237 dbSNP
rs973800840 241 dbSNP
rs921969159 257 dbSNP
rs1191432322 259 dbSNP
rs1283699541 261 dbSNP
rs537475188 262 dbSNP
rs554622164 264 dbSNP
rs1215104753 268 dbSNP
rs1000618802 269 dbSNP
rs1338596835 270 dbSNP
rs1464720006 274 dbSNP
rs1268233400 275 dbSNP
rs1203825629 277 dbSNP
rs1383121201 278 dbSNP
rs1335663917 279 dbSNP
rs1264389605 286 dbSNP
rs1429640617 295 dbSNP
rs1186164440 298 dbSNP
rs775964081 299 dbSNP
rs1446791556 300 dbSNP
rs201142369 300 dbSNP
rs796392326 300 dbSNP
rs879208936 300 dbSNP
rs932538006 300 dbSNP
rs112497077 301 dbSNP
rs1049677316 310 dbSNP
rs1183211744 314 dbSNP
rs1482368910 314 dbSNP
rs1475923442 315 dbSNP
rs1165163957 317 dbSNP
rs1469375747 320 dbSNP
rs1270757636 322 dbSNP
rs1247979937 338 dbSNP
rs2475362 339 dbSNP
rs147452254 340 dbSNP
rs1290428962 351 dbSNP
rs1052977692 354 dbSNP
rs1279652285 355 dbSNP
rs1030720552 363 dbSNP
rs891521329 364 dbSNP
rs1310541004 370 dbSNP
rs1427010072 371 dbSNP
rs1353620542 380 dbSNP
rs1235278115 392 dbSNP
rs1163266357 397 dbSNP
rs1422320205 402 dbSNP
rs1410381090 405 dbSNP
rs1294134322 412 dbSNP
rs1328762651 416 dbSNP
rs1249596949 418 dbSNP
rs1224640726 424 dbSNP
rs1237261310 448 dbSNP
rs1290798723 451 dbSNP
rs554011621 453 dbSNP
rs1318403468 454 dbSNP
rs1011353590 462 dbSNP
rs1370524280 465 dbSNP
rs1284581833 466 dbSNP
rs1407308653 471 dbSNP
rs1262887394 476 dbSNP
rs1302951293 489 dbSNP
rs1456695703 490 dbSNP
rs1347239937 499 dbSNP
rs1400279250 500 dbSNP
rs190470806 500 dbSNP
rs1043084832 501 dbSNP
rs1256078203 503 dbSNP
rs1201635712 517 dbSNP
rs1480735344 517 dbSNP
rs546109015 518 dbSNP
rs1196375241 521 dbSNP
rs1486356954 522 dbSNP
rs1188128009 529 dbSNP
rs2260836 547 dbSNP
rs1416967498 549 dbSNP
rs1160972579 554 dbSNP
rs575571092 556 dbSNP
rs1465403044 558 dbSNP
rs1326567886 560 dbSNP
rs1300999341 561 dbSNP
rs892314964 569 dbSNP
rs2678616 577 dbSNP
rs1416627830 578 dbSNP
rs1385506621 579 dbSNP
rs544301826 581 dbSNP
rs561398057 583 dbSNP
rs1313572812 584 dbSNP
rs1430316694 587 dbSNP
rs557317826 590 dbSNP
rs540374389 591 dbSNP
rs1389920867 594 dbSNP
rs1470325911 610 dbSNP
rs1428596436 612 dbSNP
rs1309472991 616 dbSNP
rs1013401709 618 dbSNP
rs1250785 621 dbSNP
rs1004990041 625 dbSNP
rs1233052263 632 dbSNP
rs1278804089 635 dbSNP
rs1185677579 636 dbSNP
rs1244577767 637 dbSNP
rs1350684942 637 dbSNP
rs1491572677 637 dbSNP
rs1203802573 638 dbSNP
rs1214327831 638 dbSNP
rs202094598 638 dbSNP
rs757927678 638 dbSNP
rs878866979 638 dbSNP
rs879137185 638 dbSNP
rs1210922420 639 dbSNP
rs1250472370 641 dbSNP
rs1479397060 645 dbSNP
rs1453547785 650 dbSNP
rs1463494805 650 dbSNP
rs532603804 650 dbSNP
rs1373528002 651 dbSNP
rs969739008 654 dbSNP
rs1250867562 656 dbSNP
rs980705091 658 dbSNP
rs1447404691 660 dbSNP
rs1171531034 661 dbSNP
rs1015124147 664 dbSNP
rs1183835542 665 dbSNP
rs1253495882 666 dbSNP
rs1196981062 673 dbSNP
rs76212521 684 dbSNP
rs1174295970 692 dbSNP
rs80290545 693 dbSNP
rs1204977442 722 dbSNP
rs1340465500 723 dbSNP
rs1317543007 726 dbSNP
rs1340055805 731 dbSNP
rs1310695998 736 dbSNP
rs1440176012 743 dbSNP
rs1393194888 744 dbSNP
rs973531760 748 dbSNP
rs921889194 752 dbSNP
rs531305134 763 dbSNP
rs74565630 764 dbSNP
rs148442664 765 dbSNP
rs1235629022 773 dbSNP
rs943959457 777 dbSNP
rs1274618375 783 dbSNP
rs1251940548 788 dbSNP
rs1182109619 791 dbSNP
rs1294442802 792 dbSNP
rs533866681 794 dbSNP
rs1206090642 805 dbSNP
rs913076225 813 dbSNP
rs1241363836 815 dbSNP
rs1251462212 817 dbSNP
rs1287730089 833 dbSNP
rs947099562 834 dbSNP
rs1347265038 835 dbSNP
rs553948336 840 dbSNP
rs1404518112 843 dbSNP
rs1388214083 845 dbSNP
rs1159924242 856 dbSNP
rs1042813464 857 dbSNP
rs879180465 863 dbSNP
rs1420606870 864 dbSNP
rs1471909808 866 dbSNP
rs1254689284 871 dbSNP
rs905491109 873 dbSNP
rs1454580094 879 dbSNP
rs1200657408 894 dbSNP
rs1451392277 903 dbSNP
rs1187826556 910 dbSNP
rs1207121947 914 dbSNP
rs746056111 922 dbSNP
rs1417361139 933 dbSNP
rs559545089 935 dbSNP
rs1172626079 955 dbSNP
rs1435568634 960 dbSNP
rs1355273471 971 dbSNP
rs1329147224 972 dbSNP
rs1056750445 975 dbSNP
rs1461153016 983 dbSNP
rs2260797 984 dbSNP
rs1432172085 985 dbSNP
rs1177772721 986 dbSNP
rs1397119728 990 dbSNP
rs896061389 1009 dbSNP
rs1250786 1010 dbSNP
rs1270124598 1014 dbSNP
rs1195713275 1015 dbSNP
rs879060983 1017 dbSNP
rs1215757971 1025 dbSNP
rs539671978 1027 dbSNP
rs1206979317 1030 dbSNP
rs1462699254 1032 dbSNP
rs1295703390 1034 dbSNP
rs1263769552 1036 dbSNP
rs1320696982 1049 dbSNP
rs1342737750 1053 dbSNP
rs556394390 1057 dbSNP
rs1227861430 1063 dbSNP
rs1274716919 1065 dbSNP
rs1364064202 1072 dbSNP
rs1318121586 1076 dbSNP
rs1454175464 1078 dbSNP
rs1468739565 1083 dbSNP
rs576273223 1085 dbSNP
rs182386178 1090 dbSNP
rs1332882582 1098 dbSNP
rs1414419042 1099 dbSNP
rs1240214155 1102 dbSNP
rs1015484278 1105 dbSNP
rs899334864 1106 dbSNP
rs868273256 1107 dbSNP
rs554663335 1109 dbSNP
rs879036610 1116 dbSNP
rs1420280646 1118 dbSNP
rs1029071490 1121 dbSNP
rs1163042359 1127 dbSNP
rs1440680732 1128 dbSNP
rs1397048693 1129 dbSNP
rs1352133905 1140 dbSNP
rs1196231431 1141 dbSNP
rs140722563 1147 dbSNP
rs540314634 1154 dbSNP
rs1247751796 1157 dbSNP
rs150049823 1160 dbSNP
rs1283140518 1162 dbSNP
rs1445128478 1163 dbSNP
rs1343900697 1173 dbSNP
rs1331441773 1176 dbSNP
rs1018984406 1179 dbSNP
rs1370341086 1179 dbSNP
rs1167057704 1182 dbSNP
rs965259453 1186 dbSNP
rs560243028 1187 dbSNP
rs868173650 1193 dbSNP
rs1471850577 1206 dbSNP
rs1354244386 1209 dbSNP
rs532541323 1215 dbSNP
rs1482651968 1220 dbSNP
rs1294736086 1234 dbSNP
rs1335075946 1236 dbSNP
rs1288692161 1244 dbSNP
rs1226175133 1248 dbSNP
rs1374893041 1249 dbSNP
rs546006377 1255 dbSNP
rs1411005445 1261 dbSNP
rs988761183 1266 dbSNP
rs1281911631 1267 dbSNP
rs1407117618 1268 dbSNP
rs1350755427 1269 dbSNP
rs1164333162 1274 dbSNP
rs913015522 1276 dbSNP
rs1410265710 1278 dbSNP
rs1159936085 1292 dbSNP
rs1216387139 1293 dbSNP
rs563159234 1297 dbSNP
rs1249487478 1310 dbSNP
rs1236896690 1311 dbSNP
rs947247979 1313 dbSNP
rs979035427 1320 dbSNP
rs927029325 1321 dbSNP
rs1318307054 1323 dbSNP
rs1284372655 1328 dbSNP
rs1227221086 1332 dbSNP
rs1420220133 1337 dbSNP
rs1475672027 1346 dbSNP
rs1286999424 1348 dbSNP
rs866357560 1349 dbSNP
rs1368770195 1354 dbSNP
rs937122457 1357 dbSNP
rs1406198689 1371 dbSNP
rs1056698781 1376 dbSNP
rs1456769622 1383 dbSNP
rs895506108 1392 dbSNP
rs531913441 1393 dbSNP
rs1160451823 1398 dbSNP
rs1189193561 1401 dbSNP
rs1486671053 1415 dbSNP
rs548908018 1420 dbSNP
rs940907176 1425 dbSNP
rs1036624463 1426 dbSNP
rs1264400572 1433 dbSNP
rs1313261387 1438 dbSNP
rs899446832 1446 dbSNP
rs374642485 1452 dbSNP
rs995014462 1454 dbSNP
rs1441063616 1455 dbSNP
rs1029598274 1456 dbSNP
rs567953207 1460 dbSNP
rs1434570341 1463 dbSNP
rs1386548338 1464 dbSNP
rs1250787 1465 dbSNP
rs1279437481 1467 dbSNP
rs1345663158 1477 dbSNP
rs199491910 1478 dbSNP
rs1430080919 1479 dbSNP
rs889191674 1486 dbSNP
rs1187556469 1487 dbSNP
rs547492187 1492 dbSNP
rs570581752 1495 dbSNP
rs539610115 1497 dbSNP
rs1255913900 1499 dbSNP
rs549718884 1512 dbSNP
rs1008997512 1513 dbSNP
rs1227979553 1516 dbSNP
rs1181332389 1517 dbSNP
rs1231448489 1523 dbSNP
rs368649080 1524 dbSNP
rs745370158 1533 dbSNP
rs1394944658 1539 dbSNP
rs1433425399 1542 dbSNP
rs1167689398 1543 dbSNP
rs1427450833 1546 dbSNP
rs1386688424 1547 dbSNP
rs1187714944 1548 dbSNP
rs1422713305 1549 dbSNP
rs956691638 1551 dbSNP
rs1174927113 1553 dbSNP
rs569879856 1554 dbSNP
rs1375500631 1555 dbSNP
rs989099073 1556 dbSNP
rs186448262 1558 dbSNP
rs1267452890 1571 dbSNP
rs1245690117 1576 dbSNP
rs1321212334 1584 dbSNP
rs1310582690 1586 dbSNP
rs1408924135 1587 dbSNP
rs771424994 1588 dbSNP
rs969064797 1590 dbSNP
rs1337169204 1594 dbSNP
rs1442598400 1595 dbSNP
rs377093922 1596 dbSNP
rs1165471223 1603 dbSNP
rs1367110376 1606 dbSNP
rs978605923 1609 dbSNP
rs369754961 1610 dbSNP
rs1366234188 1613 dbSNP
rs1160591630 1618 dbSNP
rs147041124 1619 dbSNP
rs937070357 1632 dbSNP
rs574472077 1640 dbSNP
rs916880674 1653 dbSNP
rs767118033 1658 dbSNP
rs940362834 1668 dbSNP
rs1036478392 1676 dbSNP
rs920836326 1681 dbSNP
rs930919448 1682 dbSNP
rs1287630954 1692 dbSNP
rs1050555000 1696 dbSNP
rs1332610626 1702 dbSNP
rs866838038 1706 dbSNP
rs533955623 1708 dbSNP
rs889306190 1709 dbSNP
rs1008944925 1719 dbSNP
rs1040487240 1721 dbSNP
rs1159093594 1725 dbSNP
rs892586655 1726 dbSNP
rs879774134 1731 dbSNP
rs1379766154 1739 dbSNP
rs1451303617 1743 dbSNP
rs553816714 1749 dbSNP
rs1196039407 1752 dbSNP
rs1009566236 1753 dbSNP
rs1210728968 1766 dbSNP
rs199491911 1771 dbSNP
rs1267507696 1779 dbSNP
rs1206775487 1781 dbSNP
rs576937658 1786 dbSNP
rs1275272278 1791 dbSNP
rs968637561 1793 dbSNP
rs1000541403 1800 dbSNP
rs1398130088 1818 dbSNP
rs1435293592 1819 dbSNP
rs1387285748 1823 dbSNP
rs1317912258 1832 dbSNP
rs1399492017 1834 dbSNP
rs1404959283 1835 dbSNP
rs546334455 1838 dbSNP
rs1324853840 1851 dbSNP
rs1477905604 1851 dbSNP
rs1190755134 1859 dbSNP
rs562934146 1867 dbSNP
rs576614866 1868 dbSNP
rs1304057702 1885 dbSNP
rs958540241 1894 dbSNP
rs542141394 1895 dbSNP
rs562393790 1898 dbSNP
rs1342618045 1906 dbSNP
rs1341684781 1909 dbSNP
rs1228709167 1910 dbSNP
rs1294816434 1915 dbSNP
rs1363956063 1915 dbSNP
rs1199471710 1920 dbSNP
rs962126394 1932 dbSNP
rs527250104 1936 dbSNP
rs1335461783 1941 dbSNP
rs920266200 1943 dbSNP
rs1374054098 1945 dbSNP
rs138255992 1957 dbSNP
rs1430690991 1958 dbSNP
rs1215947385 1959 dbSNP
rs561216425 1963 dbSNP
rs2700013 1965 dbSNP
rs1238057899 1969 dbSNP
rs1186766821 1978 dbSNP
rs1446957787 1982 dbSNP
rs397834164 1983 dbSNP
rs1205567610 1985 dbSNP
rs1341077861 1995 dbSNP
rs1272020286 2000 dbSNP
rs1229597914 2010 dbSNP
rs1356457937 2024 dbSNP
rs1447987826 2027 dbSNP
rs1354081808 2031 dbSNP
rs1310293908 2033 dbSNP
rs1410814761 2034 dbSNP
rs1190352136 2040 dbSNP
rs944847524 2042 dbSNP
rs1040603821 2047 dbSNP
rs1371428450 2048 dbSNP
rs1162697206 2051 dbSNP
rs892540264 2055 dbSNP
rs1253854325 2060 dbSNP
rs1163740903 2074 dbSNP
rs191211600 2076 dbSNP
rs1249281249 2089 dbSNP
rs761080986 2095 dbSNP
rs1043711855 2098 dbSNP
rs1288579110 2108 dbSNP
rs1462755522 2113 dbSNP
rs1326344499 2126 dbSNP
rs1384097303 2127 dbSNP
rs533062859 2134 dbSNP
rs549889412 2135 dbSNP
rs903857342 2136 dbSNP
rs569737682 2138 dbSNP
rs1328251182 2143 dbSNP
rs1229481200 2146 dbSNP
rs1219402692 2148 dbSNP
rs535669443 2156 dbSNP
rs868823337 2169 dbSNP
rs2757101 2170 dbSNP
rs2260749 2174 dbSNP
rs77779791 2177 dbSNP
rs1266440975 2180 dbSNP
rs368969017 2181 dbSNP
rs145993070 2183 dbSNP
rs546859493 2184 dbSNP
rs1472198405 2185 dbSNP
rs1405564771 2189 dbSNP
rs1264554390 2192 dbSNP
rs139877537 2200 dbSNP
rs961791079 2204 dbSNP
rs183334565 2209 dbSNP
rs1254881100 2210 dbSNP
rs1475995824 2211 dbSNP
rs761549925 2220 dbSNP
rs1743568 2232 dbSNP
rs556650257 2249 dbSNP
rs1305360492 2253 dbSNP
rs1221271659 2255 dbSNP
rs1451417425 2258 dbSNP
rs951808018 2259 dbSNP
rs1385588627 2261 dbSNP
rs1274477997 2263 dbSNP
rs1400629103 2265 dbSNP
rs143226021 2285 dbSNP
rs1321260321 2287 dbSNP
rs910802907 2290 dbSNP
rs944962856 2297 dbSNP
rs1353758206 2304 dbSNP
rs1414822205 2304 dbSNP
rs1424125237 2307 dbSNP
rs542429197 2309 dbSNP
rs914075968 2313 dbSNP
rs562333366 2324 dbSNP
rs945443641 2327 dbSNP
rs1316685555 2329 dbSNP
rs1187350489 2340 dbSNP
rs146183355 2348 dbSNP
rs1212760708 2349 dbSNP
rs1279981296 2353 dbSNP
rs1262942341 2356 dbSNP
rs369094692 2358 dbSNP
rs1298488481 2363 dbSNP
rs1209462567 2365 dbSNP
rs1359865235 2366 dbSNP
rs1277612753 2378 dbSNP
rs903970773 2381 dbSNP
rs938010986 2387 dbSNP
rs1055073468 2399 dbSNP
rs1167476343 2403 dbSNP
rs142505180 2406 dbSNP
rs1014137005 2411 dbSNP
rs1249451594 2437 dbSNP
rs1024117979 2443 dbSNP
rs897655296 2444 dbSNP
rs1209153790 2446 dbSNP
rs564062235 2453 dbSNP
rs531895881 2461 dbSNP
rs187635832 2463 dbSNP
rs1027807921 2474 dbSNP
rs951867268 2484 dbSNP
rs985773231 2491 dbSNP
rs1171735450 2493 dbSNP
rs1396567890 2496 dbSNP
rs1373689932 2499 dbSNP
rs1378308160 2502 dbSNP
rs1017296605 2518 dbSNP
rs1320400149 2525 dbSNP
rs1310895050 2533 dbSNP
rs966261905 2548 dbSNP
rs1307029120 2553 dbSNP
rs1370854890 2553 dbSNP
rs1460097313 2566 dbSNP
rs1303643429 2568 dbSNP
rs1372874658 2572 dbSNP
rs1369717507 2580 dbSNP
rs1164831169 2584 dbSNP
rs1389967638 2590 dbSNP
rs1309628162 2594 dbSNP
rs1378247160 2608 dbSNP
rs1234162651 2610 dbSNP
rs549590300 2612 dbSNP
rs1252920063 2617 dbSNP
rs1195467086 2626 dbSNP
rs1479757450 2646 dbSNP
rs976336254 2648 dbSNP
rs1334138020 2649 dbSNP
rs1291356260 2653 dbSNP
rs1349401714 2658 dbSNP
rs1350895302 2660 dbSNP
rs1327879843 2665 dbSNP
rs867028376 2669 dbSNP
rs914042484 2672 dbSNP
rs1250358984 2679 dbSNP
rs1392410369 2683 dbSNP
rs796849695 2685 dbSNP
rs1479467288 2688 dbSNP
rs945529081 2691 dbSNP
rs563420721 2692 dbSNP
rs1473830004 2696 dbSNP
rs1413200912 2699 dbSNP
rs1181496489 2720 dbSNP
rs1417609099 2724 dbSNP
rs1269719016 2725 dbSNP
rs1210579507 2732 dbSNP
rs1468092935 2733 dbSNP
rs979664023 2749 dbSNP
rs529047328 2753 dbSNP
rs199576055 2756 dbSNP
rs116942435 2757 dbSNP
rs1439634495 2757 dbSNP
rs534012209 2757 dbSNP
rs66479227 2758 dbSNP
rs1191658195 2766 dbSNP
rs1396888670 2767 dbSNP
rs1434910999 2768 dbSNP
rs1176898149 2773 dbSNP
rs1321924506 2777 dbSNP
rs1354103381 2778 dbSNP
rs192862574 2782 dbSNP
rs1333662287 2784 dbSNP
rs1046068295 2787 dbSNP
rs1199864473 2787 dbSNP
rs1452073694 2787 dbSNP
rs1440700836 2788 dbSNP
rs565594681 2795 dbSNP
rs528369417 2796 dbSNP
rs551301254 2797 dbSNP
rs1203246249 2798 dbSNP
rs1256322162 2799 dbSNP
rs1346879056 2799 dbSNP
rs1250789 2800 dbSNP
rs1007335658 2801 dbSNP
rs1017244275 2805 dbSNP
rs1435171121 2809 dbSNP
rs1327596083 2813 dbSNP
rs1318252179 2815 dbSNP
rs1305298375 2818 dbSNP
rs1404824417 2821 dbSNP
rs965711753 2823 dbSNP
rs997228629 2825 dbSNP
rs1170639637 2828 dbSNP
rs1181904855 2844 dbSNP
rs1467867014 2853 dbSNP
rs1190965962 2856 dbSNP
rs1256646490 2857 dbSNP
rs539847495 2863 dbSNP
rs1345367237 2864 dbSNP
rs1228598363 2866 dbSNP
rs1338192433 2867 dbSNP
rs1250790 2869 dbSNP
rs1488777970 2870 dbSNP
rs1191799539 2874 dbSNP
rs751722808 2878 dbSNP
rs967010949 2882 dbSNP
rs1418854038 2883 dbSNP
rs371282767 2884 dbSNP
rs979997135 2893 dbSNP
rs1166202280 2894 dbSNP
rs925488900 2903 dbSNP
rs1418466981 2904 dbSNP
rs878911202 2911 dbSNP
rs570149999 2915 dbSNP
rs1484570008 2921 dbSNP
rs183356982 2934 dbSNP
rs1205452378 2936 dbSNP
rs990865945 2942 dbSNP
rs1270320755 2944 dbSNP
rs1229512639 2956 dbSNP
rs1352084608 2959 dbSNP
rs556000077 2969 dbSNP
rs1250791 2971 dbSNP
rs1288849777 2976 dbSNP
rs949379419 2979 dbSNP
rs149149555 2983 dbSNP
rs919148556 2984 dbSNP
rs1290554630 2988 dbSNP
rs1443256986 2991 dbSNP
rs1354138662 2995 dbSNP
rs143230318 2999 dbSNP
rs1049346188 3000 dbSNP
rs1395222657 3005 dbSNP
rs887613949 3006 dbSNP
rs1007283375 3007 dbSNP
rs1413940580 3011 dbSNP
rs1177535016 3015 dbSNP
rs1172275119 3019 dbSNP
rs1469350963 3024 dbSNP
rs577539589 3039 dbSNP
rs543423006 3045 dbSNP
rs370066815 3046 dbSNP
rs563198351 3059 dbSNP
rs2945443 3063 dbSNP
rs1322143276 3068 dbSNP
rs200690937 3073 dbSNP
rs1333297318 3080 dbSNP
rs997573912 3091 dbSNP
rs1020647816 3096 dbSNP
rs1372956406 3102 dbSNP
rs141772176 3107 dbSNP
rs1438804376 3128 dbSNP
rs1371845548 3144 dbSNP
rs1325253921 3146 dbSNP
rs1459843820 3153 dbSNP
rs1001141439 3154 dbSNP
rs1195938819 3156 dbSNP
rs138631936 3162 dbSNP
rs528302009 3164 dbSNP
rs959539173 3166 dbSNP
rs1475022539 3182 dbSNP
rs1454419303 3190 dbSNP
rs551238109 3193 dbSNP
rs1251881271 3197 dbSNP
rs1167000016 3203 dbSNP
rs990982037 3212 dbSNP
rs1467572162 3216 dbSNP
rs1244332867 3220 dbSNP
rs2559785 3221 dbSNP
rs1406379492 3223 dbSNP
rs1159017234 3229 dbSNP
rs1282534349 3233 dbSNP
rs187847988 3241 dbSNP
rs533139087 3242 dbSNP
rs1438782671 3249 dbSNP
rs1367366937 3260 dbSNP
rs918607443 3270 dbSNP
rs1298297555 3271 dbSNP
rs1343251884 3281 dbSNP
rs929176838 3283 dbSNP
rs1435001801 3297 dbSNP
rs1354384223 3299 dbSNP
rs1048981669 3301 dbSNP
rs1171275844 3304 dbSNP
rs3827877 3307 dbSNP
rs149464575 3308 dbSNP
rs1379607223 3312 dbSNP
rs1223067072 3316 dbSNP
rs570005224 3317 dbSNP
rs745443508 3323 dbSNP
rs71186300 3325 dbSNP
rs1038909326 3327 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aauucauuguggaaGGACUUAu 5'
                        ||||||| 
Target 5' ----------caaaCCUGAAUa 3'
 		1 - 12
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000520547.2 | 3UTR | CAAACCUGAAUAAAACUACAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000520547.2 | 3UTR | CUCUCUCCCCGACACAUUUGUUAAAAUCAAACCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
76 hsa-miR-506-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT081146 LDLR low density lipoprotein receptor 2 2
MIRT083631 PRNP prion protein 2 2
MIRT157309 IKZF2 IKAROS family zinc finger 2 2 2
MIRT172369 LONRF1 LON peptidase N-terminal domain and ring finger 1 2 2
MIRT175463 ZBTB33 zinc finger and BTB domain containing 33 2 2
MIRT178171 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 4
MIRT209107 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT254771 XRCC6 X-ray repair cross complementing 6 2 6
MIRT264771 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 4
MIRT309156 FGF2 fibroblast growth factor 2 2 6
MIRT334098 SFT2D2 SFT2 domain containing 2 2 2
MIRT386044 RORA RAR related orphan receptor A 2 2
MIRT453248 FTSJ3 FtsJ RNA methyltransferase homolog 3 2 2
MIRT455924 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT456349 OLIG3 oligodendrocyte transcription factor 3 2 8
MIRT462877 ZXDB zinc finger, X-linked, duplicated B 2 2
MIRT465017 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT466897 STMN1 stathmin 1 2 2
MIRT467919 SLC20A1 solute carrier family 20 member 1 2 2
MIRT467927 SLC16A7 solute carrier family 16 member 7 2 2
MIRT468172 SGPL1 sphingosine-1-phosphate lyase 1 2 4
MIRT483372 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT484061 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT492425 RGL2 ral guanine nucleotide dissociation stimulator like 2 2 2
MIRT495350 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT496983 DNAJC27 DnaJ heat shock protein family (Hsp40) member C27 2 2
MIRT503380 SOD2 superoxide dismutase 2 2 4
MIRT505598 SLC38A1 solute carrier family 38 member 1 2 6
MIRT507384 EN2 engrailed homeobox 2 2 6
MIRT508638 RPL23A ribosomal protein L23a 2 6
MIRT509813 SULT1B1 sulfotransferase family 1B member 1 2 4
MIRT509883 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2 4
MIRT512038 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 4
MIRT512513 BTBD19 BTB domain containing 19 2 2
MIRT513071 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT514049 AGO2 argonaute 2, RISC catalytic component 2 6
MIRT516464 RAB32 RAB32, member RAS oncogene family 2 4
MIRT523441 GPR137C G protein-coupled receptor 137C 2 4
MIRT523957 DYNLT1 dynein light chain Tctex-type 1 2 4
MIRT524143 LDHD lactate dehydrogenase D 2 4
MIRT524632 C4orf32 family with sequence similarity 241 member A 2 4
MIRT531710 TFEC transcription factor EC 2 2
MIRT532813 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT534244 SLC16A1 solute carrier family 16 member 1 2 2
MIRT534328 SHISA6 shisa family member 6 2 2
MIRT543334 UTP14C UTP14C, small subunit processome component 2 2
MIRT545944 ZBTB18 zinc finger and BTB domain containing 18 2 4
MIRT549008 CCDC6 coiled-coil domain containing 6 2 2
MIRT549226 BAZ2B bromodomain adjacent to zinc finger domain 2B 2 2
MIRT550121 RPF2 ribosome production factor 2 homolog 2 2
MIRT551421 SERTM1 serine rich and transmembrane domain containing 1 2 2
MIRT556787 KLF13 Kruppel like factor 13 2 2
MIRT561372 UBXN2B UBX domain protein 2B 2 2
MIRT561849 NPTX1 neuronal pentraxin 1 2 2
MIRT563981 SLFN11 schlafen family member 11 2 2
MIRT565747 SERTAD3 SERTA domain containing 3 2 2
MIRT569130 TMC5 transmembrane channel like 5 2 4
MIRT572714 LHX6 LIM homeobox 6 2 2
MIRT624539 BROX BRO1 domain and CAAX motif containing 2 2
MIRT637034 SPTLC3 serine palmitoyltransferase long chain base subunit 3 2 2
MIRT643213 TYW3 tRNA-yW synthesizing protein 3 homolog 2 2
MIRT646884 PLSCR1 phospholipid scramblase 1 2 2
MIRT650183 LILRA2 leukocyte immunoglobulin like receptor A2 2 2
MIRT651561 WISP1 WNT1 inducible signaling pathway protein 1 2 2
MIRT665188 HAUS5 HAUS augmin like complex subunit 5 2 2
MIRT665466 WDR13 WD repeat domain 13 2 2
MIRT668763 DDR2 discoidin domain receptor tyrosine kinase 2 2 2
MIRT680605 ZNF611 zinc finger protein 611 2 2
MIRT688564 DCAF16 DDB1 and CUL4 associated factor 16 2 2
MIRT698121 TOPBP1 DNA topoisomerase II binding protein 1 2 2
MIRT699130 SMNDC1 survival motor neuron domain containing 1 2 2
MIRT712282 PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2 2
MIRT712561 CENPO centromere protein O 2 2
MIRT715358 VCAM1 vascular cell adhesion molecule 1 2 2
MIRT720209 KCNN1 potassium calcium-activated channel subfamily N member 1 2 2
MIRT732331 MTDH metadherin 2 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-506 Glucose NULL 5793 Microarray endothelial cells 24394957 2014 up-regulated
miR-506 17beta-estradiol (E2) approved 5757 Microarray MCF-7 breast cancer cells 19528081 2009 down-regulated
miR-506 17beta-estradiol (E2) approved 5757 Microarray MCF-7AKT breast cancer cells 19528081 2009 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-506 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-506 Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-506-5p Cisplatin + Decitabine sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-506-5p Tripterygium wilfordii Hook F resistant tissue
hsa-miR-506-5p Leuprorelin/Goserelin + Bicalutamide resistant tissue (prostate cancer)

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