miRTarBase - #MIRT179111


—
pre-miRNA Information
pre-miRNA hsa-mir-548aq   
Genomic Coordinates chr3: 185767847 - 185767904
Description Homo sapiens miR-548aq stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-548aq-5p
Sequence 1| GAAAGUAAUUGCUGUUUUUGCC |22
Evidence Not_experimental
Experiments
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 7 3 - 185767898 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs148741643 4 dbSNP
rs373424261 5 dbSNP
rs954388082 9 dbSNP
rs1008952958 10 dbSNP
rs1443286362 15 dbSNP
rs778852684 17 dbSNP
rs1042518237 21 dbSNP
rs1299293460 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PAFAH1B2   
Synonyms HEL-S-303
Description platelet activating factor acetylhydrolase 1b catalytic subunit 2
Transcript NM_002572   
Other Transcripts NM_001184746 , NM_001184747 , NM_001184748   
Expression
Putative miRNA Targets on PAFAH1B2
3'UTR of PAFAH1B2
(miRNA target sites are highlighted)		 
>PAFAH1B2|NM_002572|3'UTR
   1 CTGGCTCTTATCAGTGTTAATAGCATCTCAGCTTCCTCAGATCAGTTCTATCACTGGCACTACAGAATCCTTCTCTTTCT
  81 TAAGGCACTTTGCATTGTAGAATGTTCCTGGATGTTCATATCTAGTGTTTGAAGGGGAGGAGGGATTTAAACTGGTCCTG
 161 TACATAGAAGGTTTGTTTGACAGAGGAGAAAAATTAGCCAAGGAAGATTGTTGTTTAAATTCATTTGAAACCAGAAGGGG
 241 ACTTTTTAGTTGTATGTGTAACACATTCATTGAATTATTATCACTGTTTTCTTGGGACAACATCAAGCCTAAATACTGAA
 321 CAATATGAAGATTCTTTTCTTGGCCTTTCTGTGGATTATGTCATATATAATAATTATCAGAATCATTCTACTTGGCTTTA
 401 AAACATGTTTTCTCCAATTTTTTTAAGGTTCATAATTTAGCCTTTTGTTTTTATGTTGCTTAGATTCTTATGTATACTGA
 481 ATATTTTATTAACATGTAGCATCAGGTTGAACATGCTTGTCATTGATATATGGAAGATGCTATAGTTAGAAGTGAATTTG
 561 TTCTGCTTTCTTAATCTTTTCCATGCTTAGCAGTGAAAAACAGGTTTTGCCCCAGTAGAGGGATTCTTTGGAGGGTATTA
 641 TTTTTTATGCTGCTGAATATCATGTCTATAATAGACCCGTGCATGCAGCCTTTCCTCCTTATTCCCCTTCATGCCCCCCT
 721 TTCCCCTTCATTCCCCCCGCCACCCCGTTTTTTTTTTTTTTTTTTTTTTTTTGGTTCTTGTTGACATTACAAGCTTTTAA
 801 CACATTTTTGACCTAGGAGCCCTGTTGCTGGAAGTATAGTCTCCAGCCAGTTACTCTCATGATAGTACTGCTATAAAACT
 881 CATTCTTGTGTGGTGTTCTGTGCTATAGATTCTGTGTATTGCTGTTCATATTCGGAGTTCTGGTTTTGTTTTTCCCTTAA
 961 AACCTGTTAACAGTTTTTTTTGGGGGTGGGGGGATTCAGAACTCTTGTTTCCCATTCCATAGCACCTGACATTATTTCAA
1041 GTTTTATAATATCTTAAGGTGTATATTTTATTTTTTTTATTGGCTTAGTTGTTTTTTGTTTTGTTTTGTTTGAGATGGAG
1121 TTTCACTGTTGCCCAGGCTGGGGTGCAATGGTGTGATCTTGGCTCACTGCAGCCTCCACCTCCCGAGTTCAAATGATTCT
1201 CCTGCCTCAGCTTCCTGAGTAGCTGGGATTACAGGTGCATGCCACCATGCCCGGCTAATTTTTATATTTTTATTAGAGAC
1281 GGGATTTCGCCATGTTAACCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTG
1361 GGATTACAGGCATGAGCCACCGTGCCTGGCCTTATTGGCTTAGTTTTTAAATTATCCTCCAAAAATTTTGGGCCTTTTTC
1441 TGTGGGGAAACAAGTGAAGCTGCTCTTCAGCATAGACACTACCTTTATCCCATCATTTTAGTAAAAACTAGGTTTGTTTC
1521 ACTTCTGAGGTGTCTTATTAATGTACTTCATCTGAGAATTTGTTGATCTTAATGTTCGAGCTATATAAGAACTGCCATTA
1601 AAAAAAATGGGATAATAGATGATTTTATCAGTATACCTGTGGAATATGTACAAACTGGATCTATAGATATTTTGAACTGG
1681 ACCAGGTGGGTATTGAAGTAACCCATCAAAATATGCTCTGCAGTGATTCCGCTTAATGTTTAAATTCAGTAACGTACTTG
1761 AAAGGCAAATTTCAGTGCTTTTGTATGTTGGAGGAGGGCTTACTGATGCGTGCTAAGACCGATTTCTGATTGAGGGATGA
1841 ACCTTGGGCTCATTTTTTTCTTGTGAAGTCTCTTTCTAGAAAATTTTTTGGTTTTGTTCTTTTTAAAAAATACATACTTT
1921 TTTGAATGTATCATGTCTTCATTAACAACAGAAAATCCACATGGTGTTTACTAAACTTGTTTACGACATTAAAAATTTCC
2001 TTTTTATTTTTAGTAGCCCAGGTTGAGTTTTTCACAAGAGATTTTTTTCTTAGCTGAGGTATAGTTGTATAGCAAGAAGA
2081 ATTAAGCCAGATTTTTGTGTGTGGAAAGACAGTTTTCTATCCACGTCTTTTTCTGTTTGTCAGAAGGTGGGAGTATGGTC
2161 CAAATAAATCCATTAGGTTACTCCTGCAGCATGCGCTTTTAGCTTCTCTCTTGACTGAGGATCAAATATCCCTTTGTGAG
2241 CTGGCCCTCAGCTCCTTTGCTCATGTGTACAAACCTCAGATGTTACTACATTTTATATCTACCAGAGCTATTCAAGCAAT
2321 AGTATTTGAACCACTAGCCTTTTAAATAAAATTCTGCCCCATTACTGATGTGCAGATATTGAGTTCACTTTCATTTTTTG
2401 CCAGATTTCTTTGCACTACTTTAGGTAAAAATAGTTAATCTATTTTTCTTTGACATCCTAGTTTGCGTCAGTGACAGAAC
2481 TTACTGCTTAGTCTTTGTACTTTTTAAAAAATCTATAAATTTAATGCACTGTCCAAGTGAAATGTCCTAGTTGTCATTGT
2561 GATTAAGGGGCCAACTTTCCAGGCAGCTAGCAGAGATACTATTCTCTTCCTCTCCCAGCAAATTTGTATTCCTTCGCCCA
2641 CGCATTCCTGCTATACTAGATGGCAGCCAGTGATGGAACTATAAAGATGTCTGTGGTCATATGTTGAATGTGGCAGCTTG
2721 AAGATGTACTGCCACGGGTGATCTAGGGCAGGCTGTCTTCCAGTCCATGTGTTCTCGGTCGCCGTAGACAGCGCTCTGGC
2801 TACCACCGTGAGGCTACTTGAACTGTCAGGGGCATCTGCCTAAACCAGAATCTTTTGTCAGAAACCTTAACCCAACAAAA
2881 CAAATCTTGAGTAGCTCATGCCCGGCTCTTAGGAATTTTGTCTGTTTAAAAAAAAAAAAAAAAAAAAAGTCCAACTTACT
2961 TTATTTTATTTTTTTAACCTAGTCACTGTTTACAATTGTATGCTAAAGCCTGAAATATTGTCTGTGCTGTGGTGTATGAG
3041 CATTGCCAACTTTATATTTATTGCAGTGAAGAAGAAACTAAAAATATATGGAAATGAGGAGCATGTCCAAGCTCCTAAAT
3121 CCGTGTGGGTGCATGTGGGAGAAGTGAGTTAGGGCCTCTTGAAAGGAGGCTTTTTGGAGAGGGGTCCCCCAGGTTTCTTG
3201 GTGTTCCTGCTTGGGGATCACTGCTGCTAGCTGACTGGACCTCCCCATTGGAAGTTTGTGATTTTGCTTTGGCAAAGTTT
3281 CATTGACTAGTAGAACTCATTCTGTTTTAGTGTATATTTCAATATAAATGTAAACATTTTGCTCAAAAAAAAAAAAAAAA
3361 AAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ccgUUUUUGUC--GUU-AAUGAAAg 5'
             ||||| ||  ||| ||||||| 
Target 5' aaaAAAAAAAGTCCAACTTACTTTa 3'
 2939 - 2963 169.00 -5.60
2 
miRNA  3' ccgUUUUUGUCGUUAAUGAAAg 5'
             |||||:| ||  |||||| 
Target 5' ttaAAAAATA-CA--TACTTTt 3'
 1903 - 1921 137.00 -5.60
3 
miRNA  3' ccGUUUUUGUC-GUUA-AUGAAAg 5'
            :|||||:|| :||| ||:||| 
Target 5' ggTAAAAATAGTTAATCTATTTTt 3'
 2424 - 2447 132.00 -13.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26987814 12 COSMIC
COSN19729854 24 COSMIC
COSN31488577 30 COSMIC
COSN509867 37 COSMIC
COSN26569469 76 COSMIC
COSN31496220 98 COSMIC
COSN19417258 316 COSMIC
COSN20583172 345 COSMIC
COSN28201761 366 COSMIC
COSN15779005 537 COSMIC
COSN28609441 731 COSMIC
COSN6406209 748 COSMIC
COSN15606501 752 COSMIC
COSN10078853 754 COSMIC
COSN10078854 755 COSMIC
COSN5896205 1132 COSMIC
COSN1515487 1701 COSMIC
COSN22973301 1755 COSMIC
COSN6987799 2482 COSMIC
COSN8733754 2548 COSMIC
COSN27872404 2679 COSMIC
COSN32063543 2925 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1298947648 3 dbSNP
rs1321333005 8 dbSNP
rs771654363 9 dbSNP
rs759145577 10 dbSNP
rs185651296 12 dbSNP
rs1305322547 13 dbSNP
rs760891382 13 dbSNP
rs764472610 15 dbSNP
rs754241219 17 dbSNP
rs1252053345 19 dbSNP
rs757737498 21 dbSNP
rs374632211 22 dbSNP
rs1393144213 23 dbSNP
rs1208768780 28 dbSNP
rs1261978239 30 dbSNP
rs750494576 32 dbSNP
rs7938902 33 dbSNP
rs1258921326 37 dbSNP
rs1169179402 40 dbSNP
rs1451203662 44 dbSNP
rs1424737889 49 dbSNP
rs371397952 51 dbSNP
rs1197896901 54 dbSNP
rs1451877707 60 dbSNP
rs1446235553 64 dbSNP
rs554123990 69 dbSNP
rs1248208729 72 dbSNP
rs761057750 76 dbSNP
rs1231272911 83 dbSNP
rs1343406782 89 dbSNP
rs1471498731 90 dbSNP
rs1479606832 92 dbSNP
rs1437613796 107 dbSNP
rs1333096886 112 dbSNP
rs573666464 116 dbSNP
rs536284576 124 dbSNP
rs1309871834 125 dbSNP
rs1007036696 128 dbSNP
rs1412800832 134 dbSNP
rs1422954036 135 dbSNP
rs1018829901 137 dbSNP
rs556291976 144 dbSNP
rs766651558 146 dbSNP
rs1379110852 154 dbSNP
rs753955538 156 dbSNP
rs536722075 159 dbSNP
rs1157396486 162 dbSNP
rs1482490694 163 dbSNP
rs1000313850 165 dbSNP
rs1032759688 171 dbSNP
rs1206677638 208 dbSNP
rs1406355768 210 dbSNP
rs1325978334 211 dbSNP
rs1278512863 212 dbSNP
rs1220218468 228 dbSNP
rs576247497 234 dbSNP
rs1286796815 240 dbSNP
rs1228033166 241 dbSNP
rs150473023 243 dbSNP
rs1309995402 245 dbSNP
rs1445881302 253 dbSNP
rs1282242956 264 dbSNP
rs190577543 271 dbSNP
rs180788501 282 dbSNP
rs183925361 287 dbSNP
rs1349911654 288 dbSNP
rs979975015 292 dbSNP
rs1183777359 295 dbSNP
rs1471506709 301 dbSNP
rs780129348 303 dbSNP
rs1211468658 305 dbSNP
rs1444581788 306 dbSNP
rs578119156 309 dbSNP
rs768425853 321 dbSNP
rs1330132536 324 dbSNP
rs1290409699 325 dbSNP
rs974605006 326 dbSNP
rs77171490 327 dbSNP
rs930008271 337 dbSNP
rs1051028365 357 dbSNP
rs1473640857 358 dbSNP
rs1318362048 364 dbSNP
rs1456488929 366 dbSNP
rs761192597 373 dbSNP
rs560441124 376 dbSNP
rs1363257074 385 dbSNP
rs769113605 392 dbSNP
rs1473422769 408 dbSNP
rs1403197137 418 dbSNP
rs912834995 418 dbSNP
rs1410222316 419 dbSNP
rs1364174682 424 dbSNP
rs529246436 430 dbSNP
rs1302205016 433 dbSNP
rs1188371230 443 dbSNP
rs1465653098 458 dbSNP
rs1270358764 460 dbSNP
rs1219660087 464 dbSNP
rs1321277617 465 dbSNP
rs56284158 468 dbSNP
rs746811035 469 dbSNP
rs1370758070 470 dbSNP
rs540574927 471 dbSNP
rs1039874775 472 dbSNP
rs1384967408 475 dbSNP
rs1334601604 494 dbSNP
rs904058443 496 dbSNP
rs1245434720 498 dbSNP
rs1290356868 502 dbSNP
rs1348941374 517 dbSNP
rs1433862054 517 dbSNP
rs549005562 523 dbSNP
rs1425967661 525 dbSNP
rs1357083753 527 dbSNP
rs562551953 530 dbSNP
rs1168530277 531 dbSNP
rs879205260 535 dbSNP
rs1450573662 538 dbSNP
rs1264300848 542 dbSNP
rs1054232893 543 dbSNP
rs76825633 554 dbSNP
rs879715720 555 dbSNP
rs1247488758 561 dbSNP
rs781018244 561 dbSNP
rs1223918518 563 dbSNP
rs55914924 564 dbSNP
rs1009924342 567 dbSNP
rs56273235 571 dbSNP
rs1227596073 573 dbSNP
rs1023949688 580 dbSNP
rs866177426 581 dbSNP
rs1297546225 585 dbSNP
rs1217256528 592 dbSNP
rs1366511863 593 dbSNP
rs1249922007 599 dbSNP
rs1443075713 601 dbSNP
rs1368178148 605 dbSNP
rs1190293807 607 dbSNP
rs1306799830 611 dbSNP
rs1383906284 613 dbSNP
rs1375273073 616 dbSNP
rs551607965 626 dbSNP
rs1174458488 638 dbSNP
rs1432935509 639 dbSNP
rs1426266561 641 dbSNP
rs1201890756 654 dbSNP
rs1444451191 658 dbSNP
rs1251182312 677 dbSNP
rs571386787 678 dbSNP
rs1392363157 679 dbSNP
rs1252966177 680 dbSNP
rs1463213762 686 dbSNP
rs1207881015 691 dbSNP
rs1296023824 699 dbSNP
rs1395227232 708 dbSNP
rs1301643966 709 dbSNP
rs1224969662 712 dbSNP
rs1348235481 715 dbSNP
rs1287225883 719 dbSNP
rs1396092437 720 dbSNP
rs1399308488 721 dbSNP
rs201596909 721 dbSNP
rs1338674142 726 dbSNP
rs1380446993 728 dbSNP
rs1360125749 730 dbSNP
rs1245102744 731 dbSNP
rs1183052183 733 dbSNP
rs1411496369 733 dbSNP
rs1298087657 735 dbSNP
rs1308974731 737 dbSNP
rs1225517369 739 dbSNP
rs190482111 740 dbSNP
rs1205315104 741 dbSNP
rs935752823 743 dbSNP
rs1202221279 746 dbSNP
rs1239266405 746 dbSNP
rs1359076423 747 dbSNP
rs1480176802 747 dbSNP
rs1053293264 748 dbSNP
rs1162790244 748 dbSNP
rs1165420664 748 dbSNP
rs1193630062 748 dbSNP
rs1247189826 748 dbSNP
rs1321554568 748 dbSNP
rs1387123702 748 dbSNP
rs1388829222 748 dbSNP
rs1447521752 748 dbSNP
rs1458446907 748 dbSNP
rs1491516159 748 dbSNP
rs71469127 748 dbSNP
rs780327023 748 dbSNP
rs1369195175 749 dbSNP
rs1491273215 749 dbSNP
rs1293246106 750 dbSNP
rs55659804 751 dbSNP
rs11216305 752 dbSNP
rs1274572366 753 dbSNP
rs1472745673 754 dbSNP
rs369297855 755 dbSNP
rs1207775295 756 dbSNP
rs1189710499 757 dbSNP
rs1389469589 758 dbSNP
rs866099118 758 dbSNP
rs1414932400 759 dbSNP
rs1375686336 760 dbSNP
rs1427106253 761 dbSNP
rs1167953597 762 dbSNP
rs1480519922 762 dbSNP
rs1270491749 763 dbSNP
rs1202389518 765 dbSNP
rs1483042426 766 dbSNP
rs1274286232 767 dbSNP
rs1372121131 767 dbSNP
rs1466140163 770 dbSNP
rs1253462500 773 dbSNP
rs371952915 774 dbSNP
rs377139336 775 dbSNP
rs11216306 776 dbSNP
rs1403202233 778 dbSNP
rs1451836943 780 dbSNP
rs1321060464 781 dbSNP
rs11216307 782 dbSNP
rs1237615793 783 dbSNP
rs1363887418 787 dbSNP
rs1347605473 791 dbSNP
rs117842423 794 dbSNP
rs1295179407 795 dbSNP
rs1313034043 799 dbSNP
rs1034270630 802 dbSNP
rs1353906516 805 dbSNP
rs188550080 811 dbSNP
rs1322830283 814 dbSNP
rs146031077 817 dbSNP
rs11216308 820 dbSNP
rs181355369 823 dbSNP
rs1171771726 828 dbSNP
rs973921030 831 dbSNP
rs1485125156 832 dbSNP
rs918695591 837 dbSNP
rs74853754 847 dbSNP
rs1184608216 848 dbSNP
rs1441132149 859 dbSNP
rs1278429123 874 dbSNP
rs1204704231 879 dbSNP
rs185919841 884 dbSNP
rs556157493 888 dbSNP
rs1266445423 889 dbSNP
rs138790262 895 dbSNP
rs986770200 897 dbSNP
rs1374181548 899 dbSNP
rs1281300692 901 dbSNP
rs912523568 903 dbSNP
rs1268443854 906 dbSNP
rs942713909 908 dbSNP
rs1407967168 910 dbSNP
rs1433432232 910 dbSNP
rs765587298 910 dbSNP
rs10892082 911 dbSNP
rs1159779270 912 dbSNP
rs538691858 913 dbSNP
rs1184643908 917 dbSNP
rs1462951095 919 dbSNP
rs1246528362 925 dbSNP
rs936855993 931 dbSNP
rs558400011 935 dbSNP
rs75301475 936 dbSNP
rs11540099 938 dbSNP
rs1354226669 954 dbSNP
rs144675587 954 dbSNP
rs1453238892 957 dbSNP
rs1045430087 958 dbSNP
rs1318229827 964 dbSNP
rs1429661145 966 dbSNP
rs147305219 968 dbSNP
rs760357455 969 dbSNP
rs1403071566 972 dbSNP
rs1001203363 973 dbSNP
rs1164804778 974 dbSNP
rs775200829 975 dbSNP
rs898394411 977 dbSNP
rs113647409 982 dbSNP
rs373116164 982 dbSNP
rs1025404035 988 dbSNP
rs181891564 991 dbSNP
rs45535637 992 dbSNP
rs1292506217 994 dbSNP
rs1451142721 994 dbSNP
rs1246638459 999 dbSNP
rs562516073 1003 dbSNP
rs964419650 1006 dbSNP
rs1362280460 1019 dbSNP
rs139312714 1022 dbSNP
rs1433799965 1023 dbSNP
rs1342285267 1024 dbSNP
rs551837970 1027 dbSNP
rs565265709 1031 dbSNP
rs527480826 1032 dbSNP
rs1170251526 1039 dbSNP
rs116773440 1047 dbSNP
rs1189700960 1050 dbSNP
rs1422046420 1050 dbSNP
rs914035241 1060 dbSNP
rs1224808785 1064 dbSNP
rs1203670802 1071 dbSNP
rs1272358020 1071 dbSNP
rs1490831386 1071 dbSNP
rs11540098 1081 dbSNP
rs1045542827 1085 dbSNP
rs1217124699 1087 dbSNP
rs1344475392 1088 dbSNP
rs1490922750 1091 dbSNP
rs1224333809 1093 dbSNP
rs143325875 1094 dbSNP
rs375103290 1094 dbSNP
rs558680319 1094 dbSNP
rs1055441773 1096 dbSNP
rs1266303745 1099 dbSNP
rs898421583 1104 dbSNP
rs1469543600 1105 dbSNP
rs1182312453 1109 dbSNP
rs995343549 1115 dbSNP
rs1201743507 1116 dbSNP
rs1471662657 1119 dbSNP
rs1025513375 1121 dbSNP
rs766700046 1129 dbSNP
rs1252928472 1138 dbSNP
rs1480882850 1138 dbSNP
rs144864963 1141 dbSNP
rs1008001928 1143 dbSNP
rs777020441 1144 dbSNP
rs113590471 1147 dbSNP
rs538280440 1149 dbSNP
rs1348093705 1151 dbSNP
rs532559350 1154 dbSNP
rs1376160495 1160 dbSNP
rs1301576974 1175 dbSNP
rs1365155206 1185 dbSNP
rs765482224 1186 dbSNP
rs1407236650 1194 dbSNP
rs1178886805 1197 dbSNP
rs1455776996 1200 dbSNP
rs1299990368 1203 dbSNP
rs1363310597 1207 dbSNP
rs1371199248 1230 dbSNP
rs1419645298 1236 dbSNP
rs1181628869 1244 dbSNP
rs1223716114 1249 dbSNP
rs541871775 1252 dbSNP
rs975830708 1253 dbSNP
rs1205191334 1254 dbSNP
rs1348084124 1255 dbSNP
rs1362106553 1256 dbSNP
rs550664007 1257 dbSNP
rs1244202953 1260 dbSNP
rs1319301936 1275 dbSNP
rs1311233598 1277 dbSNP
rs569021116 1281 dbSNP
rs1339036417 1282 dbSNP
rs565678041 1290 dbSNP
rs1433237010 1293 dbSNP
rs1384492804 1294 dbSNP
rs1289575923 1300 dbSNP
rs1490091542 1304 dbSNP
rs1204712904 1309 dbSNP
rs958535838 1310 dbSNP
rs1366756882 1311 dbSNP
rs988433237 1312 dbSNP
rs1443870206 1313 dbSNP
rs1385697838 1314 dbSNP
rs914151294 1320 dbSNP
rs1385762881 1323 dbSNP
rs949563062 1328 dbSNP
rs1260581685 1333 dbSNP
rs982258158 1336 dbSNP
rs534420776 1338 dbSNP
rs1161476824 1340 dbSNP
rs1384324265 1342 dbSNP
rs928392824 1349 dbSNP
rs1430658216 1353 dbSNP
rs937079400 1354 dbSNP
rs1055876969 1357 dbSNP
rs1317685630 1358 dbSNP
rs1331057148 1362 dbSNP
rs1225676814 1364 dbSNP
rs1326169431 1368 dbSNP
rs1296603583 1372 dbSNP
rs1352901161 1373 dbSNP
rs898199450 1374 dbSNP
rs930971686 1380 dbSNP
rs553900163 1381 dbSNP
rs1366080313 1382 dbSNP
rs1060211 1383 dbSNP
rs1474315503 1385 dbSNP
rs1372246869 1386 dbSNP
rs1385667551 1387 dbSNP
rs1451037539 1395 dbSNP
rs1314815674 1402 dbSNP
rs1193456737 1404 dbSNP
rs1429864247 1415 dbSNP
rs1343237558 1426 dbSNP
rs1214865739 1427 dbSNP
rs1490671430 1431 dbSNP
rs1008031406 1432 dbSNP
rs1040853183 1435 dbSNP
rs1305308202 1441 dbSNP
rs996903502 1442 dbSNP
rs1229967443 1470 dbSNP
rs1343869338 1475 dbSNP
rs1282773465 1476 dbSNP
rs1243176515 1478 dbSNP
rs1032839667 1479 dbSNP
rs758406090 1490 dbSNP
rs554643874 1492 dbSNP
rs1395520537 1499 dbSNP
rs1462613756 1508 dbSNP
rs1009560194 1511 dbSNP
rs1181614101 1517 dbSNP
rs1463258803 1523 dbSNP
rs1021240774 1528 dbSNP
rs1242303144 1539 dbSNP
rs1475615113 1547 dbSNP
rs1169922308 1551 dbSNP
rs1417605033 1553 dbSNP
rs1409569151 1557 dbSNP
rs1176917357 1562 dbSNP
rs1408321291 1573 dbSNP
rs1270335157 1578 dbSNP
rs1468707907 1579 dbSNP
rs187273139 1581 dbSNP
rs764042479 1582 dbSNP
rs970945586 1584 dbSNP
rs192067458 1586 dbSNP
rs926778901 1593 dbSNP
rs879220756 1597 dbSNP
rs1224314019 1598 dbSNP
rs1325764857 1600 dbSNP
rs554423120 1600 dbSNP
rs1271611564 1601 dbSNP
rs991287002 1603 dbSNP
rs1329338185 1605 dbSNP
rs1448751554 1611 dbSNP
rs919653913 1613 dbSNP
rs765085277 1615 dbSNP
rs1430867944 1622 dbSNP
rs751547277 1631 dbSNP
rs1470111740 1653 dbSNP
rs1201765950 1657 dbSNP
rs1233945388 1664 dbSNP
rs1262415441 1671 dbSNP
rs1242846594 1675 dbSNP
rs73578684 1677 dbSNP
rs943922664 1678 dbSNP
rs1282323624 1687 dbSNP
rs1195104718 1688 dbSNP
rs1041277697 1691 dbSNP
rs899705791 1695 dbSNP
rs545121046 1700 dbSNP
rs114637182 1704 dbSNP
rs893877382 1705 dbSNP
rs1335829113 1708 dbSNP
rs1200326929 1709 dbSNP
rs1360504459 1712 dbSNP
rs79044679 1715 dbSNP
rs1468288480 1718 dbSNP
rs1176397580 1723 dbSNP
rs541543035 1725 dbSNP
rs182087844 1747 dbSNP
rs529945944 1752 dbSNP
rs1160976799 1754 dbSNP
rs1443259511 1755 dbSNP
rs1316710296 1758 dbSNP
rs550075777 1776 dbSNP
rs1429594400 1779 dbSNP
rs1283516106 1780 dbSNP
rs1346906418 1783 dbSNP
rs199697214 1783 dbSNP
rs1447663165 1784 dbSNP
rs397778984 1784 dbSNP
rs45628435 1784 dbSNP
rs780225114 1787 dbSNP
rs1218782552 1791 dbSNP
rs1282601721 1804 dbSNP
rs1357187927 1804 dbSNP
rs1246413663 1808 dbSNP
rs1314161256 1808 dbSNP
rs748841991 1810 dbSNP
rs768229136 1821 dbSNP
rs569896673 1822 dbSNP
rs973959525 1825 dbSNP
rs919692339 1833 dbSNP
rs1281894454 1837 dbSNP
rs1446212149 1838 dbSNP
rs1365468138 1839 dbSNP
rs866507992 1843 dbSNP
rs1425945685 1844 dbSNP
rs1417735562 1849 dbSNP
rs1475859441 1854 dbSNP
rs879151103 1859 dbSNP
rs1223579647 1860 dbSNP
rs982420536 1868 dbSNP
rs1223085674 1869 dbSNP
rs1290977038 1869 dbSNP
rs908177988 1871 dbSNP
rs1198829376 1874 dbSNP
rs1213686879 1875 dbSNP
rs185160798 1877 dbSNP
rs1279581889 1884 dbSNP
rs1471448613 1887 dbSNP
rs1344267420 1891 dbSNP
rs943704758 1891 dbSNP
rs1304288694 1897 dbSNP
rs1157272716 1898 dbSNP
rs1407797549 1900 dbSNP
rs551844910 1905 dbSNP
rs866789805 1913 dbSNP
rs921167775 1915 dbSNP
rs1197480225 1917 dbSNP
rs1480169793 1918 dbSNP
rs1269612810 1919 dbSNP
rs1191713915 1925 dbSNP
rs1489415344 1927 dbSNP
rs932524632 1928 dbSNP
rs1203514383 1938 dbSNP
rs747196488 1944 dbSNP
rs189920008 1955 dbSNP
rs893909814 1956 dbSNP
rs1303428771 1957 dbSNP
rs1221259293 1961 dbSNP
rs1322236456 1962 dbSNP
rs1283354545 1965 dbSNP
rs1367015284 1974 dbSNP
rs755275688 1982 dbSNP
rs945411567 1985 dbSNP
rs1371776729 1986 dbSNP
rs1298014062 1988 dbSNP
rs534387663 1996 dbSNP
rs1042417802 2000 dbSNP
rs1322324443 2001 dbSNP
rs559231738 2002 dbSNP
rs1469429490 2012 dbSNP
rs1241182938 2017 dbSNP
rs781642616 2023 dbSNP
rs1178319291 2028 dbSNP
rs1277689772 2028 dbSNP
rs1434877519 2031 dbSNP
rs1003939231 2032 dbSNP
rs747508516 2041 dbSNP
rs1458069246 2042 dbSNP
rs1239714416 2062 dbSNP
rs895360955 2063 dbSNP
rs554259808 2066 dbSNP
rs1349749976 2069 dbSNP
rs182559402 2072 dbSNP
rs995029140 2073 dbSNP
rs373158698 2074 dbSNP
rs1314563603 2076 dbSNP
rs1306954769 2090 dbSNP
rs77678768 2091 dbSNP
rs1379588560 2092 dbSNP
rs1335124769 2105 dbSNP
rs982533484 2125 dbSNP
rs188141473 2126 dbSNP
rs1304708094 2129 dbSNP
rs1451746101 2135 dbSNP
rs544997703 2138 dbSNP
rs1221949129 2142 dbSNP
rs1015290556 2143 dbSNP
rs1251339580 2144 dbSNP
rs1439626745 2147 dbSNP
rs1382017062 2162 dbSNP
rs1181496990 2165 dbSNP
rs576706494 2165 dbSNP
rs1256449838 2173 dbSNP
rs976807215 2185 dbSNP
rs921209287 2188 dbSNP
rs1259572934 2192 dbSNP
rs1218057337 2195 dbSNP
rs1356458226 2196 dbSNP
rs932534827 2197 dbSNP
rs1245674377 2215 dbSNP
rs989323129 2216 dbSNP
rs1165894688 2220 dbSNP
rs1383712726 2226 dbSNP
rs915040176 2232 dbSNP
rs773604621 2233 dbSNP
rs1420277387 2246 dbSNP
rs945190240 2263 dbSNP
rs1042523760 2264 dbSNP
rs1423804852 2271 dbSNP
rs1368760174 2283 dbSNP
rs1189208338 2288 dbSNP
rs1426352341 2290 dbSNP
rs1260511787 2293 dbSNP
rs207472401 2302 dbSNP
rs1193714769 2308 dbSNP
rs11540101 2310 dbSNP
rs1290242152 2316 dbSNP
rs759885482 2318 dbSNP
rs1396669090 2321 dbSNP
rs61905518 2325 dbSNP
rs1357497569 2335 dbSNP
rs1326820348 2337 dbSNP
rs1267542851 2339 dbSNP
rs775649408 2346 dbSNP
rs572486077 2355 dbSNP
rs1326046739 2358 dbSNP
rs1278976227 2368 dbSNP
rs1401952555 2369 dbSNP
rs11540103 2371 dbSNP
rs1343674621 2374 dbSNP
rs1301221884 2376 dbSNP
rs1453227454 2380 dbSNP
rs1316908928 2384 dbSNP
rs552189292 2393 dbSNP
rs749848445 2404 dbSNP
rs1245603858 2408 dbSNP
rs1055504579 2410 dbSNP
rs1252095959 2414 dbSNP
rs1341616947 2415 dbSNP
rs1194115209 2417 dbSNP
rs895408040 2423 dbSNP
rs1462170085 2427 dbSNP
rs561395061 2428 dbSNP
rs1241760681 2430 dbSNP
rs1478532283 2436 dbSNP
rs1027858811 2438 dbSNP
rs1452689895 2440 dbSNP
rs886643482 2441 dbSNP
rs771449820 2443 dbSNP
rs1194417441 2448 dbSNP
rs1004994833 2450 dbSNP
rs1015321595 2455 dbSNP
rs1220625360 2457 dbSNP
rs763139926 2467 dbSNP
rs764198674 2468 dbSNP
rs1435752752 2471 dbSNP
rs1463165536 2479 dbSNP
rs1165675897 2480 dbSNP
rs1398846722 2481 dbSNP
rs1470257280 2487 dbSNP
rs1325335478 2492 dbSNP
rs1338618154 2494 dbSNP
rs1389482968 2494 dbSNP
rs1291702704 2497 dbSNP
rs1331612487 2498 dbSNP
rs1380381097 2499 dbSNP
rs1395212412 2500 dbSNP
rs1296607441 2506 dbSNP
rs772352734 2506 dbSNP
rs1028374902 2507 dbSNP
rs953991746 2508 dbSNP
rs1379907064 2514 dbSNP
rs1180236775 2515 dbSNP
rs1225451524 2516 dbSNP
rs1437620809 2522 dbSNP
rs1257512487 2531 dbSNP
rs751635788 2535 dbSNP
rs989437858 2539 dbSNP
rs1200823543 2550 dbSNP
rs150529996 2552 dbSNP
rs543292502 2558 dbSNP
rs1219861846 2559 dbSNP
rs1261795849 2570 dbSNP
rs374589090 2573 dbSNP
rs945213551 2574 dbSNP
rs1187504272 2576 dbSNP
rs977893468 2579 dbSNP
rs1404664214 2586 dbSNP
rs15030 2596 dbSNP
rs1429946020 2597 dbSNP
rs1190491720 2598 dbSNP
rs1157357963 2602 dbSNP
rs1414575608 2602 dbSNP
rs1470065428 2616 dbSNP
rs939397824 2621 dbSNP
rs1180864602 2629 dbSNP
rs1055134692 2636 dbSNP
rs1422374170 2637 dbSNP
rs916607079 2638 dbSNP
rs1444204669 2642 dbSNP
rs930636601 2643 dbSNP
rs1178557668 2644 dbSNP
rs1352891777 2645 dbSNP
rs1309776062 2649 dbSNP
rs1403771064 2649 dbSNP
rs1242080932 2650 dbSNP
rs1465445536 2651 dbSNP
rs542784334 2654 dbSNP
rs886674608 2656 dbSNP
rs1005026483 2661 dbSNP
rs796298332 2665 dbSNP
rs767434171 2670 dbSNP
rs1346288746 2675 dbSNP
rs1361706407 2677 dbSNP
rs1160920619 2679 dbSNP
rs1423159207 2694 dbSNP
rs1413435032 2703 dbSNP
rs1225396444 2714 dbSNP
rs1182676266 2715 dbSNP
rs1240497432 2719 dbSNP
rs532259249 2726 dbSNP
rs1488631126 2733 dbSNP
rs1286693362 2734 dbSNP
rs1028071927 2737 dbSNP
rs953880347 2739 dbSNP
rs1228602326 2744 dbSNP
rs1357993828 2745 dbSNP
rs1312146745 2751 dbSNP
rs1267946757 2757 dbSNP
rs1010557480 2759 dbSNP
rs1340550144 2760 dbSNP
rs755901577 2767 dbSNP
rs1022238515 2770 dbSNP
rs12574377 2775 dbSNP
rs12273027 2777 dbSNP
rs376427366 2778 dbSNP
rs559052797 2781 dbSNP
rs753590091 2782 dbSNP
rs1407332359 2783 dbSNP
rs1203069988 2784 dbSNP
rs528110141 2786 dbSNP
rs1478192649 2794 dbSNP
rs547860853 2795 dbSNP
rs991345065 2800 dbSNP
rs1489839276 2804 dbSNP
rs12576725 2806 dbSNP
rs1245955092 2807 dbSNP
rs114732975 2808 dbSNP
rs1323235075 2809 dbSNP
rs536440284 2814 dbSNP
rs1426525292 2816 dbSNP
rs193148674 2817 dbSNP
rs1049028582 2828 dbSNP
rs1318014461 2830 dbSNP
rs1279526957 2831 dbSNP
rs560946715 2832 dbSNP
rs1367477939 2841 dbSNP
rs908147104 2847 dbSNP
rs1159744617 2859 dbSNP
rs1353054450 2869 dbSNP
rs1365383233 2876 dbSNP
rs1425959732 2882 dbSNP
rs1466329371 2882 dbSNP
rs940915060 2884 dbSNP
rs1424398009 2886 dbSNP
rs570237952 2886 dbSNP
rs1191659740 2892 dbSNP
rs11860 2902 dbSNP
rs528321169 2903 dbSNP
rs183558724 2904 dbSNP
rs1366919109 2905 dbSNP
rs12574603 2909 dbSNP
rs1224890996 2912 dbSNP
rs1309769151 2921 dbSNP
rs1311063835 2923 dbSNP
rs1302594088 2924 dbSNP
rs1315556153 2925 dbSNP
rs1371704869 2925 dbSNP
rs1308988952 2927 dbSNP
rs1358502515 2927 dbSNP
rs1177743091 2928 dbSNP
rs1179684115 2928 dbSNP
rs1229007842 2928 dbSNP
rs1234426514 2928 dbSNP
rs1239643324 2928 dbSNP
rs1256061412 2928 dbSNP
rs1378325998 2928 dbSNP
rs1402702346 2928 dbSNP
rs1439971285 2928 dbSNP
rs1482652328 2928 dbSNP
rs150627380 2928 dbSNP
rs548543438 2928 dbSNP
rs1239837106 2929 dbSNP
rs1292905034 2930 dbSNP
rs1490416929 2931 dbSNP
rs1224178099 2933 dbSNP
rs1241361356 2946 dbSNP
rs1244478058 2949 dbSNP
rs1379522931 2949 dbSNP
rs76205794 2950 dbSNP
rs1395607995 2951 dbSNP
rs902050686 2954 dbSNP
rs996352646 2955 dbSNP
rs1049964829 2960 dbSNP
rs879085509 2964 dbSNP
rs1157923676 2966 dbSNP
rs1358520913 2966 dbSNP
rs1420087655 2967 dbSNP
rs796985142 2969 dbSNP
rs879003193 2969 dbSNP
rs889518978 2972 dbSNP
rs1417193596 2977 dbSNP
rs1256301395 2981 dbSNP
rs1183078040 2993 dbSNP
rs540022922 2996 dbSNP
rs1217900127 3004 dbSNP
rs1010587196 3006 dbSNP
rs1385571625 3010 dbSNP
rs1021933101 3016 dbSNP
rs559233868 3019 dbSNP
rs966619353 3022 dbSNP
rs1349428834 3041 dbSNP
rs572446398 3049 dbSNP
rs1300462046 3051 dbSNP
rs1380624549 3051 dbSNP
rs1297522421 3055 dbSNP
rs535063951 3056 dbSNP
rs370263047 3057 dbSNP
rs1400523293 3062 dbSNP
rs1362296990 3068 dbSNP
rs999482002 3073 dbSNP
rs143337330 3088 dbSNP
rs960851177 3093 dbSNP
rs559867617 3096 dbSNP
rs1476555888 3099 dbSNP
rs1316183959 3100 dbSNP
rs1361953788 3106 dbSNP
rs1195100767 3122 dbSNP
rs916671051 3123 dbSNP
rs952102432 3124 dbSNP
rs1247793553 3132 dbSNP
rs1287280713 3133 dbSNP
rs1320638846 3138 dbSNP
rs1216968675 3151 dbSNP
rs984764501 3153 dbSNP
rs1278916530 3164 dbSNP
rs778629739 3167 dbSNP
rs1219217198 3185 dbSNP
rs565199967 3190 dbSNP
rs1328109942 3191 dbSNP
rs907844538 3192 dbSNP
rs940695838 3192 dbSNP
rs1391101503 3193 dbSNP
rs1294935903 3198 dbSNP
rs1252505593 3202 dbSNP
rs188998050 3206 dbSNP
rs747679472 3211 dbSNP
rs976776321 3212 dbSNP
rs1479116600 3215 dbSNP
rs1376455712 3223 dbSNP
rs1198726312 3236 dbSNP
rs1434122366 3249 dbSNP
rs1269899232 3254 dbSNP
rs1456398269 3258 dbSNP
rs543900517 3260 dbSNP
rs146727549 3267 dbSNP
rs1200630743 3274 dbSNP
rs1446211711 3289 dbSNP
rs1180387345 3290 dbSNP
rs1232365297 3291 dbSNP
rs1413304575 3294 dbSNP
rs1331523698 3301 dbSNP
rs1305348033 3303 dbSNP
rs932158136 3311 dbSNP
rs771353528 3321 dbSNP
rs1411183048 3322 dbSNP
rs889545521 3323 dbSNP
rs192574402 3326 dbSNP
rs576983465 3328 dbSNP
rs545763837 3337 dbSNP
rs746249453 3339 dbSNP
rs999186862 3345 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 5049.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 5049.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset GSM545214
Method / RBP PAR-CLIP / AGO3
Cell line / Condition HEK293 / Control
Location of target site ENST00000527958.1 | 3UTR | UUGCCAGAUUUCUUUGCACUACUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000527958.1 | 3UTR | CAGAUUUCUUUGCACUACUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000527958.1 | 3UTR | AUUUCUUUGCACUACUUUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000527958.1 | 3UTR | AUUUCUUUGCACUACUUUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
184 hsa-miR-548aq-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057134 DDIT4 DNA damage inducible transcript 4 2 4
MIRT063382 ETNK1 ethanolamine kinase 1 2 2
MIRT072505 RAB8B RAB8B, member RAS oncogene family 2 2
MIRT082197 ACTN4 actinin alpha 4 2 6
MIRT083047 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT085199 SLC5A3 solute carrier family 5 member 3 2 4
MIRT088917 FOXN2 forkhead box N2 2 4
MIRT089509 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 6
MIRT092051 ABHD5 abhydrolase domain containing 5 2 2
MIRT094694 FEM1C fem-1 homolog C 2 2
MIRT095408 UBE2D2 ubiquitin conjugating enzyme E2 D2 2 2
MIRT096514 BRIX1 BRX1, biogenesis of ribosomes 2 2
MIRT101306 FAM135A family with sequence similarity 135 member A 2 2
MIRT103369 CBX3 chromobox 3 2 2
MIRT103887 FOXK1 forkhead box K1 2 2
MIRT104347 CLDN12 claudin 12 2 2
MIRT104511 PEG10 paternally expressed 10 2 6
MIRT111811 MPZL1 myelin protein zero like 1 2 2
MIRT177250 BMI1 BMI1 proto-oncogene, polycomb ring finger 2 2
MIRT177285 COMMD3-BMI1 COMMD3-BMI1 readthrough 2 2
MIRT177635 UBE2D1 ubiquitin conjugating enzyme E2 D1 2 6
MIRT178051 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT179111 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 6
MIRT179598 CAPZA1 capping actin protein of muscle Z-line alpha subunit 1 2 6
MIRT195309 LEPROT leptin receptor overlapping transcript 2 2
MIRT203155 BACH1 BTB domain and CNC homolog 1 2 2
MIRT208439 ZBTB38 zinc finger and BTB domain containing 38 2 2
MIRT214587 SMAD5 SMAD family member 5 2 4
MIRT216114 IL6ST interleukin 6 signal transducer 2 2
MIRT216366 CCNB1 cyclin B1 2 4
MIRT220062 MDFIC MyoD family inhibitor domain containing 2 2
MIRT226739 ANP32B acidic nuclear phosphoprotein 32 family member B 2 4
MIRT227708 TBC1D13 TBC1 domain family member 13 2 2
MIRT230083 SH3BGRL SH3 domain binding glutamate rich protein like 2 2
MIRT248647 HMGN2 high mobility group nucleosomal binding domain 2 2 4
MIRT254803 XRCC6 X-ray repair cross complementing 6 2 6
MIRT264390 YAP1 Yes associated protein 1 2 2
MIRT266985 LRRC55 leucine rich repeat containing 55 2 4
MIRT273960 SPRYD4 SPRY domain containing 4 2 2
MIRT281812 MAP2K1 mitogen-activated protein kinase kinase 1 2 2
MIRT293265 DR1 down-regulator of transcription 1 2 2
MIRT297107 RGPD4 RANBP2-like and GRIP domain containing 4 2 2
MIRT308184 PDE12 phosphodiesterase 12 2 2
MIRT309027 USP53 ubiquitin specific peptidase 53 2 2
MIRT311481 PRRC1 proline rich coiled-coil 1 2 2
MIRT312599 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT328139 ZNF711 zinc finger protein 711 2 2
MIRT329324 FAM53C family with sequence similarity 53 member C 2 2
MIRT334652 NEK7 NIMA related kinase 7 2 2
MIRT340683 THRAP3 thyroid hormone receptor associated protein 3 2 2
MIRT378867 ITGB8 integrin subunit beta 8 2 2
MIRT395804 SPCS3 signal peptidase complex subunit 3 2 2
MIRT405650 WBP4 WW domain binding protein 4 2 4
MIRT408296 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT442110 ZNRF2 zinc and ring finger 2 2 8
MIRT442853 GTF2H5 general transcription factor IIH subunit 5 2 2
MIRT443129 VLDLR very low density lipoprotein receptor 2 2
MIRT443160 ZDHHC21 zinc finger DHHC-type containing 21 2 2
MIRT443311 PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 2 2
MIRT445093 ZNF207 zinc finger protein 207 2 2
MIRT445397 PTCHD1 patched domain containing 1 2 4
MIRT447083 MCC mutated in colorectal cancers 2 2
MIRT447313 ZNF562 zinc finger protein 562 2 2
MIRT447526 MRPS5 mitochondrial ribosomal protein S5 2 2
MIRT449524 TM6SF1 transmembrane 6 superfamily member 1 2 2
MIRT449915 C11orf34 placenta expressed transcript 1 1 2
MIRT450564 SHFM1 SEM1, 26S proteasome complex subunit 2 2
MIRT450732 PVRL3 nectin cell adhesion molecule 3 2 2
MIRT454936 ANKEF1 ankyrin repeat and EF-hand domain containing 1 2 12
MIRT455905 KIF2C kinesin family member 2C 2 2
MIRT463745 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon 2 8
MIRT471195 PHB2 prohibitin 2 2 2
MIRT472777 MTMR6 myotubularin related protein 6 2 8
MIRT474470 KLHL11 kelch like family member 11 2 8
MIRT475998 GTPBP2 GTP binding protein 2 2 2
MIRT482290 AGO2 argonaute 2, RISC catalytic component 2 4
MIRT485871 ALG9 ALG9, alpha-1,2-mannosyltransferase 2 2
MIRT486205 ERH ERH, mRNA splicing and mitosis factor 2 4
MIRT488622 FAM3C family with sequence similarity 3 member C 2 6
MIRT489997 DDB1 damage specific DNA binding protein 1 2 2
MIRT493489 IPMK inositol polyphosphate multikinase 2 2
MIRT494293 CEP120 centrosomal protein 120 2 2
MIRT498005 ZBTB20 zinc finger and BTB domain containing 20 2 2
MIRT498486 PTBP2 polypyrimidine tract binding protein 2 2 10
MIRT498572 TMEM30B transmembrane protein 30B 2 2
MIRT499880 SVOP SV2 related protein 2 10
MIRT500233 INHBA inhibin beta A subunit 2 10
MIRT500707 TRIM37 tripartite motif containing 37 2 2
MIRT501001 SPPL2A signal peptide peptidase like 2A 2 4
MIRT501036 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 6
MIRT502749 CLIP1 CAP-Gly domain containing linker protein 1 2 8
MIRT502811 CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 2 6
MIRT502900 CDK4 cyclin dependent kinase 4 2 8
MIRT503496 ZNF154 zinc finger protein 154 2 6
MIRT503730 GRM5 glutamate metabotropic receptor 5 2 2
MIRT505150 YOD1 YOD1 deubiquitinase 2 2
MIRT505815 RSBN1 round spermatid basic protein 1 2 8
MIRT505854 POLR1B RNA polymerase I subunit B 2 4
MIRT509297 NPM3 nucleophosmin/nucleoplasmin 3 2 6
MIRT516842 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT520532 TRA2B transformer 2 beta homolog 2 2
MIRT520736 TM9SF3 transmembrane 9 superfamily member 3 2 6
MIRT525416 SHISA9 shisa family member 9 2 4
MIRT525880 ARL13B ADP ribosylation factor like GTPase 13B 2 2
MIRT526026 RBM4B RNA binding motif protein 4B 2 2
MIRT526097 TMEM41B transmembrane protein 41B 2 2
MIRT527944 FRY FRY microtubule binding protein 2 2
MIRT528831 RAB32 RAB32, member RAS oncogene family 2 2
MIRT531075 SLC9A4 solute carrier family 9 member A4 2 4
MIRT535508 PANX1 pannexin 1 2 2
MIRT536695 IKZF5 IKAROS family zinc finger 5 2 2
MIRT536848 HMBOX1 homeobox containing 1 2 2
MIRT537215 GDE1 glycerophosphodiester phosphodiesterase 1 2 4
MIRT537847 EFNA5 ephrin A5 2 2
MIRT538358 CSE1L chromosome segregation 1 like 2 4
MIRT541255 GPC4 glypican 4 2 2
MIRT543248 PEX7 peroxisomal biogenesis factor 7 2 2
MIRT543463 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT543724 XKR9 XK related 9 2 2
MIRT543920 ESYT1 extended synaptotagmin 1 2 2
MIRT544012 KLRC3 killer cell lectin like receptor C3 2 2
MIRT544083 METTL8 methyltransferase like 8 2 2
MIRT544200 ANGPTL3 angiopoietin like 3 2 2
MIRT544821 ACSM2B acyl-CoA synthetase medium chain family member 2B 2 2
MIRT545059 PRELID1 PRELI domain containing 1 2 2
MIRT545227 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT545302 SPC25 SPC25, NDC80 kinetochore complex component 2 2
MIRT545563 GIMAP4 GTPase, IMAP family member 4 2 2
MIRT546510 SIK1 salt inducible kinase 1 2 2
MIRT546927 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 2
MIRT547688 KPNA1 karyopherin subunit alpha 1 2 4
MIRT547781 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT548700 CRNKL1 crooked neck pre-mRNA splicing factor 1 2 2
MIRT548914 CHEK2 checkpoint kinase 2 2 4
MIRT549970 RPL7L1 ribosomal protein L7 like 1 2 4
MIRT550502 TMEM241 transmembrane protein 241 2 2
MIRT551062 MKLN1 muskelin 1 2 2
MIRT552824 XIAP X-linked inhibitor of apoptosis 2 4
MIRT553158 UBE2H ubiquitin conjugating enzyme E2 H 2 2
MIRT553843 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT554271 SIX4 SIX homeobox 4 2 2
MIRT555794 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 2
MIRT556331 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556512 LIPA lipase A, lysosomal acid type 2 2
MIRT556706 KLHL28 kelch like family member 28 2 2
MIRT556765 KLF7 Kruppel like factor 7 2 2
MIRT557003 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT557159 HOXA13 homeobox A13 2 2
MIRT557500 GPR27 G protein-coupled receptor 27 2 4
MIRT558115 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 2
MIRT559357 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT560348 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT561312 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT561896 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT561940 MFSD9 major facilitator superfamily domain containing 9 2 2
MIRT562948 TNIP2 TNFAIP3 interacting protein 2 2 2
MIRT563304 BBS10 Bardet-Biedl syndrome 10 2 2
MIRT563418 KIF3A kinesin family member 3A 2 2
MIRT563575 KIAA1586 KIAA1586 2 2
MIRT565888 NHS NHS actin remodeling regulator 2 2
MIRT566094 RCC2 regulator of chromosome condensation 2 2 2
MIRT566409 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT567272 HSP90AA1 heat shock protein 90 alpha family class A member 1 2 2
MIRT571481 CCDC80 coiled-coil domain containing 80 2 2
MIRT572952 VDAC2 voltage dependent anion channel 2 2 2
MIRT573641 ZNF724P zinc finger protein 724 2 2
MIRT573730 KHSRP KH-type splicing regulatory protein 2 2
MIRT609101 SMIM15 small integral membrane protein 15 2 6
MIRT617949 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT618392 PRKG2 protein kinase, cGMP-dependent, type II 2 2
MIRT619640 PLEKHG7 pleckstrin homology and RhoGEF domain containing G7 2 2
MIRT623468 KDM5A lysine demethylase 5A 2 2
MIRT629158 CTCFL CCCTC-binding factor like 2 2
MIRT638534 LYRM2 LYR motif containing 2 2 2
MIRT649496 CLDN16 claudin 16 2 2
MIRT683161 MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 2 2
MIRT691673 SLC43A3 solute carrier family 43 member 3 2 2
MIRT693214 MKI67 marker of proliferation Ki-67 2 2
MIRT695347 AQP3 aquaporin 3 (Gill blood group) 2 2
MIRT701036 PCGF5 polycomb group ring finger 5 2 2
MIRT708766 RYBP RING1 and YY1 binding protein 2 2
MIRT717571 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT719299 SETD7 SET domain containing lysine methyltransferase 7 2 2
MIRT725185 SDAD1 SDA1 domain containing 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-548aq Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer tissue
hsa-miR-548aq-5p Erlotinib 176870 NSC718781 approved sensitive High Non-Small Cell Lung Cancer tissue
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-548aq-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-548aq-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-548aq-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)

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