miRTarBase - #MIRT180896


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pre-miRNA Information
pre-miRNA hsa-mir-4739   
Genomic Coordinates chr17: 79707176 - 79707249
Description Homo sapiens miR-4739 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4739
Sequence 10| AAGGGAGGAGGAGCGGAGGGGCCCU |34
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1416844919 3 dbSNP
rs1313792237 5 dbSNP
rs1350222948 10 dbSNP
rs1440530436 13 dbSNP
rs73410309 14 dbSNP
rs1223789593 15 dbSNP
rs1279007964 18 dbSNP
rs1345189697 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol RPRD2   
Synonyms HSPC099, KIAA0460
Description regulation of nuclear pre-mRNA domain containing 2
Transcript NM_015203   
Expression
Putative miRNA Targets on RPRD2
3'UTR of RPRD2
(miRNA target sites are highlighted)		 
>RPRD2|NM_015203|3'UTR
   1 TGGAAACCAAGGGAAAGGCATTTTGAACAGTCTAGAGAACATTGGAAGTAGGAGTTTGGTTTATTGTTGTTGTTTTTATT
  81 TGTTTTCTCTTTCTCGATTTTTTTTTTATTATAACAAAGGGCCTCTCTTCCAAAGTAAGAAATCACATACGCTTACGTTT
 161 TACTATTCAATTCAATCCTCCCTCCCATTGCACTTATCTACCTTCCCCAAGTTGTTTGTATTAAAAAAAAAAAAAAAAAA
 241 AAAAAGTAAAGAAACACAACCAAAGCCATTTCATTTGGCTGGGGGGTTGGGGAGTGGGGAGGAAAACAATCTTTATTTTA
 321 CCCCATCTATTGAAGAGTATTATTACATTTGAAATAAAACTTCCATCAGTACAGATAACCACATGTGCAATGTTGGGATG
 401 TTATTTTGGGCTTGGCTTATCGAGTAGTCAATGGAAGGATTCCCGTCCCCTCTCTCGGCAGCTTAGTAACTGCTGTAGCC
 481 AGCTCGGCTCCCTTCCCTGTGTATCTGTGTCCTGCTAACAGCCAAGAGATGTTGCAAGGGAGGAAATGTGAGAGACCTTG
 561 AACCTGTCAGGTTTATTTGTTTTGTTTTTAAAGGCATGTTGAAGTTTAGTTCTTTACCCTTCTCCTAAAATCTTTTTTTA
 641 ATCAGCCTCAAGGTTAAAATAAGGAGTGACTACAGTATGTAAAATAAGGAAAGGAAGCATTAATGGTGTGATGTGACCTG
 721 CCTGTTTTTTTGTAAACAAGAGAATAGGAAATGTTTTCAAGGTAGTTTCACATGTCTTGCACCAAGCTCATGCCTCTTGC
 801 TTTTCCTTTTTGACTTTATCTCCCTCAGTTTTTCTTCTGCTGTGGCCAGAAAGACAGTCACTACAGTTGACTATTGATAC
 881 AAAGGTGCAACAGAAATATTATCCCTGCATTTTTAAATATAAGAAGTAGACATTAATTTTACCATGGTGCCTCCCTAATG
 961 TAAGTGATATTTATTGGTGGTTTTCAACAAAGGTTAACTATTAAAGAAAGAAATATTTGTCTTTATCTTCCTTTTCCCCT
1041 TGCCTCAGTCGTGTTATTCACCCCTATTCTTGATATTTTAAAGGAGGAGATTCAGTAGCATTTTCCTTTATATTATACAC
1121 ATGTGTCTATCCCATTTCAAGGCTCAAGTCTTACCCCCACCTCTCGCTCCCAATAGGAAATAAAGACCATTTCTGCCCTT
1201 AGTTGTTTTACATGCAAGATAAGTGCTTTCCTTCTCCCTGGACTGAAAGACTTGTTTGTATTTCTACATCTAGTACTTGG
1281 GAAATAGACAATCACTGTACTTTGAGTGTTTATATCTTTATATCTAGGGACACTGAAAAGTAAATGTTGCTTTACTACAA
1361 TTTTTTTTTAATTTAGTGTCTTACCCCAAGGCATACTCAACTGATAATCTCCAGCTAGATGAGTAAAACAGTATGTGTTT
1441 AGTTTTCCAGAGAATTCTGGCAAGTTTCATATTTTCTTCCAAGTTAGTATAGAACTAACTATAGGAAGTATGGGGTTGCT
1521 TTTTCCTCCAGTAGAATATTAAAGATGGGGGAGGGTGGGCAATGTAGTGACAGAAAATGATTCTCTCAGAATGAACTTTT
1601 CAGAGAAAGAGCAGCATAAACCAGGTGCACATCATGATTTGGGAGTTTTTGCGTAATTTATTCTGTTATTTATTTGGGCT
1681 CGCCATGTGTTCTGGGGTTAGGATGCTGCAGGTCATTCATCTTCTTAATGCCTGTCTGGTCTTAAGCCAACTGTTCTTTC
1761 TTTCCTCGACCCTCTCTGCCCTGTAGCTCTCCCCACAAAAATGCATGATACCATGACCTTACGTGTGGGATGGGGTATGT
1841 AGTGTAGCAAAGAAAAGAAAGTATAGTTATATTGAGTCCTAAGACATTTGTTAGGGAAAAGCATAAGAGAAAATGGGGTG
1921 GGAGGTGGGGAAATGATATTTGACTTTCAAAATTGAAATAGGTTTTTTTTTTGCAGAAATTAAATGGGATGTTTTTCATT
2001 CTAGAATAAAAGAATGTGAATTCTCTTTGCTGCTCTTGTTTAAGCTAAAAGTAGTGTTTACTTGATAAGGCTCTCTGACC
2081 ATTTAATTTTTATCAGAAAATGTGGGGATGTCAGGAAAGTGGCTTCCTGAACGTTGGGGCGGGATAATTGTCCTCAAAAG
2161 TATGATGGTTAATACATGAAAGGAAGACTTTGTTGGACAGTTTCGAAGGTGGGCTTTTAAGGAGTTGGGTTTTTGTGGGG
2241 TACTTTTTTGTTTTTTAAGCCACAAAATCCTCAATATGTTTGTTTTAGGATGGAAGTGAGGATTTGTATGAGACTGTCAG
2321 CTATTAATTTTAAGGAAATCTTAAAATTTACATTTACATCAGTAAATGAAGATGACAGTGTGTATATATGTGATAAATAG
2401 TGAAACAGAAAAGACAGTTCTGGTATTCATAACGTGAAAGAAAGGGGTTTTATTCTTTCTGTGTCTGTGATTTAAAACTC
2481 CGTGACCATGCTCTGACTTTTGTATTTCAACCTGAGTTTAAACAAATAAACAAGATATTTTTTAAAGAAAGCATAACATA
2561 GTGTGTCTTAGCAAGGACATGATTCATATGGAAGCAGAATGTGAGAAGTTGTAAGGTCCTTGGTACTCACTGTAAAATCA
2641 CAGACAGAGAATTGGTAGGGGTTGTGAATACACTAGTACCACTTAAAGTTCAGTGATACAGTTCAGAAATAGGGTCCTTA
2721 AGTATTTTGAAAGAGTTTACTCTTCAGTCAGCTTAGATGAGAGCTCTCTCCCTGCTCCCCTCTACCCTCTCAAAAGTTGA
2801 GAGTAAATAGAATTTGGTTTGATTCCAGGGAGGGGAAAATAAGCAGAGAATAGGACTTTTATACTTTCCAATACCAGGAA
2881 TAAAATGTTTGTGATATATATGGGTCCAGCAAACCTATCGAGATAATGTGAATACGATAAACTTCCTAATGGCAGGATAT
2961 TCACTCTCAATCCTGAAGTTACCGGTTCCTGCAGAATTGAGCTTCAGCTGTTACTGTTTTGAAGCCGCTGTAAATTACTG
3041 CTTTCCCCAGTTCCCCCACTATTTTTTTTAAGTGGGCGGGGGCGCCTGTTAAGATCTAAAATAGATATGTTGGATTGATA
3121 TTCTCACGTGTTCGGTGTGGAAAACAAAACAAGTACATGCTTTAGAAGCAACAACAATGAAATCCTTTTGAAATGTGTGT
3201 TAATATCGTTTAATAAAATAACTAGTTTGAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uccCGG-GGAGGCGAGGAGGAGGGAa 5'
             |||  ||| ||||| |:||||| 
Target 5' gtaGCCAGCTCGGCTCC-CTTCCCTg 3'
 475 - 499 157.00 -30.40
2 
miRNA  3' ucccgGGGAGGCGAGG--AGGAGGGAa 5'
               |: |:|  |:|  |||||||| 
Target 5' ttttaCTATTCAATTCAATCCTCCCTc 3'
 158 - 184 154.00 -19.10
3 
miRNA  3' uccCGGGGAGGCGAGGA----GGAGGGAa 5'
             |::|:|:| :||||    ||||:|| 
Target 5' actGTTCTTTCTTTCCTCGACCCTCTCTg 3'
 1750 - 1778 152.00 -22.22
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30107050 9 COSMIC
COSN28781126 10 COSMIC
COSN32065633 11 COSMIC
COSN23013895 29 COSMIC
COSN30193975 33 COSMIC
COSN30119290 68 COSMIC
COSN18725026 108 COSMIC
COSN20090354 252 COSMIC
COSN6002464 424 COSMIC
COSN22276932 513 COSMIC
COSN29315190 561 COSMIC
COSN7465834 597 COSMIC
COSN17296783 821 COSMIC
COSN31778145 1188 COSMIC
COSN31778097 1189 COSMIC
COSN32057201 1415 COSMIC
COSN29915944 1648 COSMIC
COSN32056029 1683 COSMIC
COSN4900753 1971 COSMIC
COSN28970901 1973 COSMIC
COSN31778121 2142 COSMIC
COSN26563434 2169 COSMIC
COSN8319665 2179 COSMIC
COSN28640724 2236 COSMIC
COSN8636168 2236 COSMIC
COSN26572579 2251 COSMIC
COSN20095345 2564 COSMIC
COSN6002465 2624 COSMIC
COSN20095346 2646 COSMIC
COSN5865546 2659 COSMIC
COSN5731700 2879 COSMIC
COSN28201787 2977 COSMIC
COSN16719146 2998 COSMIC
COSN1089202 3149 COSMIC
rs12040949 1653 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs587687687 4 dbSNP
rs1309508681 5 dbSNP
rs16837095 8 dbSNP
rs7002 10 dbSNP
rs1486412000 14 dbSNP
rs753279422 16 dbSNP
rs866941824 19 dbSNP
rs367784870 20 dbSNP
rs145871523 33 dbSNP
rs1191730658 34 dbSNP
rs778667656 35 dbSNP
rs963413600 37 dbSNP
rs769378790 43 dbSNP
rs766209438 50 dbSNP
rs1271979190 59 dbSNP
rs961461358 64 dbSNP
rs1308480413 67 dbSNP
rs920115614 70 dbSNP
rs974130900 70 dbSNP
rs1229823324 71 dbSNP
rs1249848840 72 dbSNP
rs1290453456 73 dbSNP
rs1438953359 76 dbSNP
rs587636549 81 dbSNP
rs932800336 86 dbSNP
rs985766795 90 dbSNP
rs1259516894 92 dbSNP
rs587709927 96 dbSNP
rs587596238 97 dbSNP
rs1219541240 98 dbSNP
rs944266560 98 dbSNP
rs748861465 101 dbSNP
rs112042154 102 dbSNP
rs1181034232 107 dbSNP
rs1262115548 108 dbSNP
rs1430102168 109 dbSNP
rs992304541 110 dbSNP
rs587649430 112 dbSNP
rs587712886 117 dbSNP
rs1308055059 122 dbSNP
rs1461687304 123 dbSNP
rs1299528000 131 dbSNP
rs587631700 142 dbSNP
rs143871570 151 dbSNP
rs1175034875 152 dbSNP
rs187900262 157 dbSNP
rs1388553209 158 dbSNP
rs934427313 158 dbSNP
rs1297734611 166 dbSNP
rs1302798808 170 dbSNP
rs587617212 171 dbSNP
rs1054112669 176 dbSNP
rs1384283636 185 dbSNP
rs1293701239 188 dbSNP
rs1454115073 190 dbSNP
rs1364811909 192 dbSNP
rs746107027 195 dbSNP
rs587676200 197 dbSNP
rs775719631 198 dbSNP
rs1345854305 199 dbSNP
rs1247777279 203 dbSNP
rs1194789884 215 dbSNP
rs931357258 219 dbSNP
rs1208401230 221 dbSNP
rs1346922367 221 dbSNP
rs1261250116 222 dbSNP
rs61819382 222 dbSNP
rs1180378838 223 dbSNP
rs1202037701 223 dbSNP
rs1208603850 223 dbSNP
rs1239794292 223 dbSNP
rs1253835636 223 dbSNP
rs1260380779 223 dbSNP
rs1280768312 223 dbSNP
rs1348730762 223 dbSNP
rs1350969160 223 dbSNP
rs1419175614 223 dbSNP
rs1485333132 223 dbSNP
rs61486244 223 dbSNP
rs774191644 223 dbSNP
rs918094080 224 dbSNP
rs1184630305 225 dbSNP
rs1247016225 228 dbSNP
rs77520158 229 dbSNP
rs1356721400 235 dbSNP
rs1414679498 235 dbSNP
rs1454479930 237 dbSNP
rs1336552630 239 dbSNP
rs1399325794 240 dbSNP
rs1195147620 241 dbSNP
rs1382250451 241 dbSNP
rs1392671516 242 dbSNP
rs1013156729 243 dbSNP
rs1413424127 244 dbSNP
rs1185238995 245 dbSNP
rs76993680 245 dbSNP
rs1258147743 246 dbSNP
rs1474838678 246 dbSNP
rs1173169334 247 dbSNP
rs1445093719 247 dbSNP
rs1205906191 248 dbSNP
rs1404526689 248 dbSNP
rs1346382095 249 dbSNP
rs1048389763 252 dbSNP
rs1271334289 252 dbSNP
rs945448537 253 dbSNP
rs1455664478 256 dbSNP
rs1286481707 257 dbSNP
rs1336015899 257 dbSNP
rs45595332 258 dbSNP
rs1364694379 260 dbSNP
rs1441863033 261 dbSNP
rs1319452609 262 dbSNP
rs1305924838 266 dbSNP
rs1368799803 267 dbSNP
rs1218721787 268 dbSNP
rs755932157 268 dbSNP
rs1435349348 273 dbSNP
rs1390472173 274 dbSNP
rs1162095224 281 dbSNP
rs1460481195 282 dbSNP
rs6656322 287 dbSNP
rs1414383248 292 dbSNP
rs1248910272 293 dbSNP
rs1164959170 305 dbSNP
rs907116706 310 dbSNP
rs1241279433 312 dbSNP
rs925308027 319 dbSNP
rs1307613049 322 dbSNP
rs587730032 330 dbSNP
rs1466417809 336 dbSNP
rs1251377251 338 dbSNP
rs936694024 344 dbSNP
rs587615885 346 dbSNP
rs1292169441 347 dbSNP
rs1038907278 366 dbSNP
rs961350799 367 dbSNP
rs1267305301 377 dbSNP
rs900403563 382 dbSNP
rs933251963 386 dbSNP
rs1366848944 391 dbSNP
rs1323512762 402 dbSNP
rs1439473363 405 dbSNP
rs1349919405 406 dbSNP
rs1051512227 408 dbSNP
rs1250759106 410 dbSNP
rs587691197 421 dbSNP
rs1177342206 422 dbSNP
rs1409327771 423 dbSNP
rs1027477645 425 dbSNP
rs1393450901 428 dbSNP
rs886273367 432 dbSNP
rs1004633971 439 dbSNP
rs1388296548 445 dbSNP
rs767448665 446 dbSNP
rs1462302825 454 dbSNP
rs898819240 457 dbSNP
rs772906260 458 dbSNP
rs587731073 459 dbSNP
rs966029873 462 dbSNP
rs1392639529 474 dbSNP
rs1435827273 476 dbSNP
rs587630425 478 dbSNP
rs1375401433 481 dbSNP
rs112722056 483 dbSNP
rs765723119 486 dbSNP
rs1287664740 487 dbSNP
rs1353796384 498 dbSNP
rs760497023 500 dbSNP
rs1431358740 501 dbSNP
rs1234981122 506 dbSNP
rs992420559 508 dbSNP
rs1373371433 514 dbSNP
rs1270872521 518 dbSNP
rs1433979870 520 dbSNP
rs1450734232 524 dbSNP
rs61410121 529 dbSNP
rs1175500911 530 dbSNP
rs1025103906 532 dbSNP
rs1054165890 537 dbSNP
rs1253120784 555 dbSNP
rs587763814 557 dbSNP
rs747950563 572 dbSNP
rs967322659 574 dbSNP
rs1211343901 576 dbSNP
rs978186049 576 dbSNP
rs1312341872 580 dbSNP
rs1280311712 597 dbSNP
rs1221525006 603 dbSNP
rs1372020257 605 dbSNP
rs948457827 620 dbSNP
rs1044628493 622 dbSNP
rs925380621 626 dbSNP
rs1234078446 631 dbSNP
rs1478577607 633 dbSNP
rs907007302 633 dbSNP
rs587638551 639 dbSNP
rs1466370390 641 dbSNP
rs1002815234 642 dbSNP
rs1157232165 644 dbSNP
rs759618422 644 dbSNP
rs1412774142 648 dbSNP
rs1161541740 664 dbSNP
rs1474512152 671 dbSNP
rs1257441102 679 dbSNP
rs936774543 689 dbSNP
rs974685395 694 dbSNP
rs1484456636 698 dbSNP
rs1475735170 708 dbSNP
rs587694266 712 dbSNP
rs1213173120 719 dbSNP
rs1411866802 721 dbSNP
rs1328121997 725 dbSNP
rs995506314 728 dbSNP
rs1405030040 737 dbSNP
rs1026949608 739 dbSNP
rs954280127 742 dbSNP
rs921943929 746 dbSNP
rs1381025459 781 dbSNP
rs587752678 788 dbSNP
rs1430268632 790 dbSNP
rs587656603 791 dbSNP
rs1322562697 792 dbSNP
rs1459956724 793 dbSNP
rs1307337270 799 dbSNP
rs1356079138 801 dbSNP
rs587707918 806 dbSNP
rs886265831 810 dbSNP
rs1426117484 820 dbSNP
rs1417796650 821 dbSNP
rs1291256412 824 dbSNP
rs1006950150 827 dbSNP
rs374138115 840 dbSNP
rs1248271750 843 dbSNP
rs1355421567 846 dbSNP
rs1214742818 852 dbSNP
rs940548698 856 dbSNP
rs1323495884 861 dbSNP
rs1037437608 862 dbSNP
rs965497455 863 dbSNP
rs12758270 864 dbSNP
rs1001300172 865 dbSNP
rs1322835752 866 dbSNP
rs752821704 874 dbSNP
rs1486312122 876 dbSNP
rs879881198 877 dbSNP
rs1294245777 897 dbSNP
rs1190477621 899 dbSNP
rs1353274370 900 dbSNP
rs1236045373 901 dbSNP
rs1170116072 902 dbSNP
rs191863913 921 dbSNP
rs895488618 925 dbSNP
rs1390358263 926 dbSNP
rs587742059 929 dbSNP
rs914208745 932 dbSNP
rs1452236401 942 dbSNP
rs1266034695 945 dbSNP
rs1472683116 963 dbSNP
rs1421738433 965 dbSNP
rs1013845447 968 dbSNP
rs587622867 975 dbSNP
rs1422003768 987 dbSNP
rs587617261 988 dbSNP
rs1159399232 989 dbSNP
rs1204121827 994 dbSNP
rs771860223 1003 dbSNP
rs1025684942 1004 dbSNP
rs1232341910 1006 dbSNP
rs587671760 1008 dbSNP
rs1375961556 1017 dbSNP
rs1301986327 1026 dbSNP
rs1436465908 1027 dbSNP
rs928488012 1031 dbSNP
rs1371746610 1034 dbSNP
rs1307992447 1040 dbSNP
rs1339586706 1041 dbSNP
rs148182059 1044 dbSNP
rs1271563150 1051 dbSNP
rs1032523352 1052 dbSNP
rs958079784 1063 dbSNP
rs897078332 1064 dbSNP
rs145899107 1065 dbSNP
rs1248280365 1072 dbSNP
rs1048889333 1073 dbSNP
rs752734124 1073 dbSNP
rs1483370042 1081 dbSNP
rs1213584603 1082 dbSNP
rs974800078 1089 dbSNP
rs1276497467 1094 dbSNP
rs1208470240 1103 dbSNP
rs1277125578 1117 dbSNP
rs140509417 1121 dbSNP
rs200068502 1123 dbSNP
rs1007407183 1128 dbSNP
rs587595996 1132 dbSNP
rs1235460120 1135 dbSNP
rs1194416194 1142 dbSNP
rs1287860496 1154 dbSNP
rs1410957202 1160 dbSNP
rs777090466 1161 dbSNP
rs1352932564 1164 dbSNP
rs770455503 1166 dbSNP
rs921934204 1167 dbSNP
rs1244040978 1169 dbSNP
rs1400994854 1170 dbSNP
rs954743163 1175 dbSNP
rs1332720153 1182 dbSNP
rs587673894 1190 dbSNP
rs765424803 1196 dbSNP
rs1157850480 1208 dbSNP
rs1472839042 1209 dbSNP
rs1031088991 1222 dbSNP
rs1185467670 1227 dbSNP
rs182900132 1231 dbSNP
rs1441663235 1232 dbSNP
rs187541513 1234 dbSNP
rs1256639840 1239 dbSNP
rs587732713 1242 dbSNP
rs989719580 1255 dbSNP
rs1267577046 1258 dbSNP
rs752781138 1259 dbSNP
rs969738099 1269 dbSNP
rs980293428 1277 dbSNP
rs928367120 1281 dbSNP
rs1436941955 1282 dbSNP
rs1037911285 1286 dbSNP
rs920436029 1289 dbSNP
rs1397405152 1291 dbSNP
rs1386086145 1292 dbSNP
rs1319233386 1294 dbSNP
rs1457331708 1300 dbSNP
rs938374051 1301 dbSNP
rs972570318 1301 dbSNP
rs370851316 1311 dbSNP
rs1401058168 1312 dbSNP
rs1161360091 1315 dbSNP
rs1320099636 1319 dbSNP
rs1368814040 1321 dbSNP
rs918396854 1324 dbSNP
rs587620486 1336 dbSNP
rs937036391 1341 dbSNP
rs1247661286 1342 dbSNP
rs1209390060 1344 dbSNP
rs1466335514 1347 dbSNP
rs1271395873 1353 dbSNP
rs1055593955 1359 dbSNP
rs1286318151 1361 dbSNP
rs1303720554 1361 dbSNP
rs80136909 1362 dbSNP
rs895478785 1370 dbSNP
rs1362518543 1372 dbSNP
rs1296454321 1375 dbSNP
rs1372457929 1377 dbSNP
rs1230522069 1378 dbSNP
rs1321075241 1379 dbSNP
rs1273569497 1381 dbSNP
rs1404687672 1382 dbSNP
rs1344985815 1384 dbSNP
rs889815844 1385 dbSNP
rs1447462758 1391 dbSNP
rs942710723 1397 dbSNP
rs1206059379 1400 dbSNP
rs1189423719 1431 dbSNP
rs1286736470 1434 dbSNP
rs587624533 1451 dbSNP
rs7411534 1460 dbSNP
rs999532971 1465 dbSNP
rs1452626640 1470 dbSNP
rs1292668753 1475 dbSNP
rs587740817 1475 dbSNP
rs1194395900 1476 dbSNP
rs1455636338 1481 dbSNP
rs1341856550 1484 dbSNP
rs1275858260 1501 dbSNP
rs1041399065 1502 dbSNP
rs1366995925 1508 dbSNP
rs1376973766 1509 dbSNP
rs893952978 1520 dbSNP
rs587621903 1526 dbSNP
rs999788289 1534 dbSNP
rs1032883778 1535 dbSNP
rs958238441 1548 dbSNP
rs1427790264 1554 dbSNP
rs996208784 1558 dbSNP
rs587697229 1568 dbSNP
rs193010881 1579 dbSNP
rs954692288 1583 dbSNP
rs1431858833 1586 dbSNP
rs1423331288 1588 dbSNP
rs12042229 1589 dbSNP
rs907884633 1601 dbSNP
rs1248567455 1604 dbSNP
rs1396298132 1604 dbSNP
rs1180619762 1608 dbSNP
rs962237794 1610 dbSNP
rs1275790535 1615 dbSNP
rs1207741137 1618 dbSNP
rs1384547221 1623 dbSNP
rs1276096654 1628 dbSNP
rs1035319693 1632 dbSNP
rs1218093060 1632 dbSNP
rs1276160963 1646 dbSNP
rs1407908368 1646 dbSNP
rs141156871 1649 dbSNP
rs12040949 1653 dbSNP
rs1175587912 1654 dbSNP
rs1240332895 1656 dbSNP
rs1427336041 1662 dbSNP
rs931150679 1666 dbSNP
rs587664082 1670 dbSNP
rs984480418 1671 dbSNP
rs1184720777 1680 dbSNP
rs911140055 1681 dbSNP
rs1327430397 1682 dbSNP
rs587744070 1683 dbSNP
rs1055541719 1686 dbSNP
rs1041032794 1688 dbSNP
rs1264456071 1694 dbSNP
rs901153157 1699 dbSNP
rs935436654 1701 dbSNP
rs916976184 1705 dbSNP
rs1230194133 1707 dbSNP
rs1052452532 1710 dbSNP
rs1274023146 1720 dbSNP
rs949840470 1723 dbSNP
rs1208104361 1729 dbSNP
rs1266709556 1745 dbSNP
rs1011072060 1749 dbSNP
rs1413294121 1751 dbSNP
rs1024183766 1754 dbSNP
rs1422638503 1757 dbSNP
rs587774348 1761 dbSNP
rs1438487498 1766 dbSNP
rs1004173134 1768 dbSNP
rs587640155 1769 dbSNP
rs61819384 1779 dbSNP
rs1249614128 1784 dbSNP
rs1206229266 1786 dbSNP
rs1472135368 1787 dbSNP
rs1041741364 1788 dbSNP
rs1268264924 1790 dbSNP
rs1217846759 1799 dbSNP
rs959674186 1806 dbSNP
rs748951500 1811 dbSNP
rs993950028 1823 dbSNP
rs768232614 1824 dbSNP
rs1385197681 1829 dbSNP
rs952694696 1835 dbSNP
rs1434701744 1836 dbSNP
rs983975007 1838 dbSNP
rs935578569 1839 dbSNP
rs1053998117 1842 dbSNP
rs1456840297 1843 dbSNP
rs1358132464 1847 dbSNP
rs1165858770 1849 dbSNP
rs78610677 1849 dbSNP
rs1425950445 1853 dbSNP
rs1386667358 1854 dbSNP
rs1162310024 1856 dbSNP
rs1186253969 1857 dbSNP
rs772070545 1859 dbSNP
rs1448559499 1861 dbSNP
rs1248101902 1866 dbSNP
rs1396523092 1867 dbSNP
rs996323834 1867 dbSNP
rs1029136353 1871 dbSNP
rs1310379119 1873 dbSNP
rs976616211 1874 dbSNP
rs1221974551 1878 dbSNP
rs1272275037 1880 dbSNP
rs1227933436 1882 dbSNP
rs868286401 1889 dbSNP
rs1409573387 1890 dbSNP
rs1008992839 1894 dbSNP
rs1294328817 1894 dbSNP
rs935326884 1895 dbSNP
rs1052508367 1897 dbSNP
rs778441669 1898 dbSNP
rs1294663962 1899 dbSNP
rs1459940714 1908 dbSNP
rs962110337 1917 dbSNP
rs1242816396 1919 dbSNP
rs946756438 1925 dbSNP
rs1045247802 1926 dbSNP
rs973722421 1940 dbSNP
rs587598841 1943 dbSNP
rs1003818720 1963 dbSNP
rs1490837496 1963 dbSNP
rs201235561 1963 dbSNP
rs35529963 1963 dbSNP
rs1207454622 1964 dbSNP
rs1343068759 1974 dbSNP
rs1181613258 1982 dbSNP
rs1253322170 1993 dbSNP
rs1231112409 2004 dbSNP
rs1249503332 2011 dbSNP
rs1056714681 2013 dbSNP
rs1482711816 2017 dbSNP
rs1349181639 2018 dbSNP
rs895519984 2029 dbSNP
rs1410848341 2036 dbSNP
rs115369351 2039 dbSNP
rs1421853083 2043 dbSNP
rs991290351 2053 dbSNP
rs1464277294 2056 dbSNP
rs952503977 2061 dbSNP
rs917094080 2078 dbSNP
rs949798206 2097 dbSNP
rs1018125962 2103 dbSNP
rs1409682378 2113 dbSNP
rs1181127804 2119 dbSNP
rs587705990 2121 dbSNP
rs964202662 2124 dbSNP
rs977237126 2133 dbSNP
rs1463055722 2134 dbSNP
rs924263805 2141 dbSNP
rs1369211584 2142 dbSNP
rs1429628699 2143 dbSNP
rs1327637111 2145 dbSNP
rs1314044349 2157 dbSNP
rs1229588244 2178 dbSNP
rs1332677308 2189 dbSNP
rs935708638 2189 dbSNP
rs1393928501 2190 dbSNP
rs1401065223 2196 dbSNP
rs1336755087 2201 dbSNP
rs373776254 2205 dbSNP
rs922520293 2206 dbSNP
rs6587754 2210 dbSNP
rs894038750 2213 dbSNP
rs1365318432 2215 dbSNP
rs1394658449 2218 dbSNP
rs1423404572 2229 dbSNP
rs1257152406 2236 dbSNP
rs773173675 2237 dbSNP
rs915196989 2243 dbSNP
rs1463573690 2244 dbSNP
rs1267638973 2247 dbSNP
rs932250337 2248 dbSNP
rs1312262581 2253 dbSNP
rs1327298214 2263 dbSNP
rs1353557969 2275 dbSNP
rs183969184 2276 dbSNP
rs1230661830 2277 dbSNP
rs1045536077 2283 dbSNP
rs1315349591 2283 dbSNP
rs1454285188 2285 dbSNP
rs1385783702 2292 dbSNP
rs1319379721 2293 dbSNP
rs1050520811 2311 dbSNP
rs1272525270 2313 dbSNP
rs890635754 2319 dbSNP
rs1161191800 2320 dbSNP
rs1457242221 2321 dbSNP
rs762595746 2323 dbSNP
rs1185628216 2324 dbSNP
rs764636591 2324 dbSNP
rs1247488972 2325 dbSNP
rs587747286 2329 dbSNP
rs1341575188 2331 dbSNP
rs939495100 2341 dbSNP
rs1441819160 2347 dbSNP
rs1009387535 2348 dbSNP
rs760456914 2352 dbSNP
rs1209575030 2355 dbSNP
rs1056775591 2367 dbSNP
rs898084247 2374 dbSNP
rs1211439755 2377 dbSNP
rs186867607 2380 dbSNP
rs1296151928 2383 dbSNP
rs1430851313 2387 dbSNP
rs771226972 2399 dbSNP
rs1328086864 2409 dbSNP
rs1482153329 2409 dbSNP
rs1046741370 2415 dbSNP
rs1365946901 2416 dbSNP
rs111855989 2421 dbSNP
rs994865890 2430 dbSNP
rs1261965939 2435 dbSNP
rs1450983516 2437 dbSNP
rs776513654 2444 dbSNP
rs1245098843 2445 dbSNP
rs958574954 2448 dbSNP
rs1388958663 2466 dbSNP
rs991414669 2480 dbSNP
rs759865574 2482 dbSNP
rs759653655 2483 dbSNP
rs997977025 2487 dbSNP
rs765503368 2493 dbSNP
rs1340828506 2503 dbSNP
rs1272626838 2511 dbSNP
rs956634687 2516 dbSNP
rs977557461 2517 dbSNP
rs1127211 2518 dbSNP
rs1407794701 2520 dbSNP
rs968438361 2528 dbSNP
rs587701911 2532 dbSNP
rs1411915088 2534 dbSNP
rs935763241 2536 dbSNP
rs1423140212 2537 dbSNP
rs1172136075 2538 dbSNP
rs374429502 2538 dbSNP
rs926700665 2553 dbSNP
rs1432110749 2554 dbSNP
rs1437488580 2555 dbSNP
rs939380464 2559 dbSNP
rs1233862600 2560 dbSNP
rs1204756844 2561 dbSNP
rs144974315 2561 dbSNP
rs35083786 2561 dbSNP
rs192118072 2562 dbSNP
rs760747895 2573 dbSNP
rs1235207371 2576 dbSNP
rs1324131927 2581 dbSNP
rs1285153333 2588 dbSNP
rs1303296394 2588 dbSNP
rs989750902 2590 dbSNP
rs929564452 2598 dbSNP
rs920931398 2602 dbSNP
rs184242753 2606 dbSNP
rs1444635558 2608 dbSNP
rs1357655351 2609 dbSNP
rs189390739 2616 dbSNP
rs912043377 2624 dbSNP
rs1408440478 2627 dbSNP
rs147054931 2640 dbSNP
rs1472582414 2643 dbSNP
rs1039331766 2646 dbSNP
rs944913765 2650 dbSNP
rs750632193 2660 dbSNP
rs899599320 2666 dbSNP
rs372805678 2680 dbSNP
rs897888784 2681 dbSNP
rs587641660 2684 dbSNP
rs761686016 2687 dbSNP
rs1264516643 2713 dbSNP
rs1427831476 2715 dbSNP
rs1029469238 2717 dbSNP
rs1316339261 2719 dbSNP
rs1307360784 2723 dbSNP
rs1431904904 2729 dbSNP
rs764574114 2731 dbSNP
rs892279958 2737 dbSNP
rs1364685386 2739 dbSNP
rs1283781484 2745 dbSNP
rs1009513731 2748 dbSNP
rs1385066241 2750 dbSNP
rs1049058251 2757 dbSNP
rs1459163848 2759 dbSNP
rs1161673587 2765 dbSNP
rs1403984856 2770 dbSNP
rs1413578156 2770 dbSNP
rs1022623542 2773 dbSNP
rs1318785477 2778 dbSNP
rs587705089 2783 dbSNP
rs1244443779 2786 dbSNP
rs1441697880 2789 dbSNP
rs587763485 2797 dbSNP
rs894516037 2798 dbSNP
rs1261269888 2811 dbSNP
rs1217911036 2817 dbSNP
rs1319673623 2821 dbSNP
rs1290835977 2837 dbSNP
rs1246983919 2838 dbSNP
rs867201953 2848 dbSNP
rs968118037 2854 dbSNP
rs1365618429 2856 dbSNP
rs1434495343 2857 dbSNP
rs36020363 2857 dbSNP
rs1363225539 2860 dbSNP
rs1291114151 2861 dbSNP
rs1024250532 2866 dbSNP
rs1033652852 2872 dbSNP
rs13057 2879 dbSNP
rs1330864244 2881 dbSNP
rs998670574 2892 dbSNP
rs1031940795 2894 dbSNP
rs12141218 2898 dbSNP
rs1166126256 2902 dbSNP
rs1427372851 2919 dbSNP
rs989865511 2921 dbSNP
rs1188185188 2927 dbSNP
rs920920108 2936 dbSNP
rs919450851 2937 dbSNP
rs929446889 2943 dbSNP
rs750293569 2956 dbSNP
rs1043293 2957 dbSNP
rs1487882600 2963 dbSNP
rs751163639 2965 dbSNP
rs1191058707 2969 dbSNP
rs1253255396 2973 dbSNP
rs1473771209 2976 dbSNP
rs943598828 2977 dbSNP
rs746984210 2984 dbSNP
rs944963765 2985 dbSNP
rs1406133517 2988 dbSNP
rs1039789304 2990 dbSNP
rs1036495246 2994 dbSNP
rs587706271 3000 dbSNP
rs1167205428 3013 dbSNP
rs933764978 3014 dbSNP
rs1431311072 3016 dbSNP
rs1050787638 3017 dbSNP
rs1199830425 3018 dbSNP
rs892332107 3027 dbSNP
rs587606687 3028 dbSNP
rs1352323015 3042 dbSNP
rs1195431449 3044 dbSNP
rs930708349 3054 dbSNP
rs1043529597 3062 dbSNP
rs1323394482 3062 dbSNP
rs903779235 3062 dbSNP
rs1287441251 3063 dbSNP
rs1225937345 3078 dbSNP
rs1306816279 3078 dbSNP
rs879144259 3078 dbSNP
rs759150713 3079 dbSNP
rs1396782877 3080 dbSNP
rs1299336872 3081 dbSNP
rs1012951461 3082 dbSNP
rs1229618065 3083 dbSNP
rs1287306114 3084 dbSNP
rs770398284 3085 dbSNP
rs1177044336 3086 dbSNP
rs587667573 3087 dbSNP
rs960679929 3091 dbSNP
rs1013707614 3094 dbSNP
rs1026393954 3097 dbSNP
rs907094293 3104 dbSNP
rs747697939 3105 dbSNP
rs999180217 3106 dbSNP
rs1460907712 3108 dbSNP
rs866720283 3122 dbSNP
rs1263891514 3126 dbSNP
rs771609761 3128 dbSNP
rs1275941505 3134 dbSNP
rs777632206 3135 dbSNP
rs1335938347 3141 dbSNP
rs142336167 3141 dbSNP
rs1450075581 3147 dbSNP
rs1381386018 3151 dbSNP
rs776233954 3156 dbSNP
rs1011276384 3157 dbSNP
rs1251489201 3158 dbSNP
rs746984780 3161 dbSNP
rs1454151536 3173 dbSNP
rs1365368394 3177 dbSNP
rs1185670305 3202 dbSNP
rs975003428 3208 dbSNP
rs193071728 3209 dbSNP
rs1411982279 3211 dbSNP
rs1404828404 3228 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 23248.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ucccggggaggcgaggAGGAGGGAa 5'
                          |||||||| 
Target 5' --------------aaUCCUCCCUc 3'
 		1 - 11
2 
miRNA  3' ucccGGGGAGG----CGAGGA------GGAGGGAA 5'
              :||||||    || |:|      |:||||  
Target 5' auccUCCCUCCCAUUGCACUUAUCUACCUUCCCCA 3'
 		2 - 36
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000539519.1 | 3UTR | AAUCCUCCCUCCCAUUGCACUUAUCUACCUUCCCCAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
206 hsa-miR-4739 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057839 SLC30A7 solute carrier family 30 member 7 2 2
MIRT059680 CRTC2 CREB regulated transcription coactivator 2 2 2
MIRT083284 ZCCHC3 zinc finger CCHC-type containing 3 2 6
MIRT117523 MIDN midnolin 2 2
MIRT125598 SCD stearoyl-CoA desaturase 2 2
MIRT158424 TNRC6B trinucleotide repeat containing 6B 2 4
MIRT180896 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT183522 BTG2 BTG anti-proliferation factor 2 2 4
MIRT197842 DCAF7 DDB1 and CUL4 associated factor 7 2 2
MIRT227610 ZBTB34 zinc finger and BTB domain containing 34 2 2
MIRT260049 JUN Jun proto-oncogene, AP-1 transcription factor subunit 2 2
MIRT266231 PEX11B peroxisomal biogenesis factor 11 beta 2 2
MIRT267389 TMEM138 transmembrane protein 138 2 2
MIRT284431 CAPN15 calpain 15 2 2
MIRT293023 ZNF566 zinc finger protein 566 2 2
MIRT318024 CENPQ centromere protein Q 2 2
MIRT339336 SESN2 sestrin 2 2 2
MIRT445769 CCND3 cyclin D3 2 2
MIRT451026 MYH14 myosin heavy chain 14 2 8
MIRT451436 TJP3 tight junction protein 3 2 4
MIRT451704 C1RL complement C1r subcomponent like 2 2
MIRT451968 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452008 FKBP5 FK506 binding protein 5 2 2
MIRT452471 SORCS2 sortilin related VPS10 domain containing receptor 2 2 2
MIRT452720 DTHD1 death domain containing 1 2 2
MIRT453490 PITPNM3 PITPNM family member 3 2 2
MIRT454314 ZNF134 zinc finger protein 134 2 2
MIRT454401 NRG4 neuregulin 4 2 2
MIRT454498 SLC29A1 solute carrier family 29 member 1 (Augustine blood group) 2 2
MIRT454839 POLR2J3 RNA polymerase II subunit J3 2 2
MIRT455147 TBC1D25 TBC1 domain family member 25 2 2
MIRT455887 KIF2C kinesin family member 2C 2 2
MIRT456138 SAMD10 sterile alpha motif domain containing 10 2 2
MIRT456165 TTF2 transcription termination factor 2 2 2
MIRT457167 MXRA7 matrix remodeling associated 7 2 2
MIRT457444 NOL10 nucleolar protein 10 2 2
MIRT457571 ZNF34 zinc finger protein 34 2 2
MIRT457632 UPK3BL uroplakin 3B like 1 2 2
MIRT458748 CES2 carboxylesterase 2 2 2
MIRT459493 CCL11 C-C motif chemokine ligand 11 2 2
MIRT459936 HHIP hedgehog interacting protein 2 4
MIRT460104 GNG3 G protein subunit gamma 3 2 2
MIRT460154 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT460195 PCYT1A phosphate cytidylyltransferase 1, choline, alpha 2 2
MIRT460324 SH3RF1 SH3 domain containing ring finger 1 2 2
MIRT460665 IGFBP4 insulin like growth factor binding protein 4 2 2
MIRT460703 RNF157 ring finger protein 157 2 2
MIRT460898 UBE2S ubiquitin conjugating enzyme E2 S 2 2
MIRT461581 SCO1 SCO1, cytochrome c oxidase assembly protein 2 4
MIRT461825 SNAP23 synaptosome associated protein 23 2 2
MIRT462041 FAAH fatty acid amide hydrolase 2 2
MIRT462119 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT462467 GCDH glutaryl-CoA dehydrogenase 2 2
MIRT462811 NTN1 netrin 1 2 2
MIRT463339 ZFHX3 zinc finger homeobox 3 2 2
MIRT463452 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463928 WNT3 Wnt family member 3 2 2
MIRT464274 VCL vinculin 2 2
MIRT465378 TPM3 tropomyosin 3 2 6
MIRT465558 TOB2 transducer of ERBB2, 2 2 2
MIRT466363 THBS1 thrombospondin 1 2 2
MIRT467363 SP2 Sp2 transcription factor 2 2
MIRT467781 SLC2A4 solute carrier family 2 member 4 2 2
MIRT467826 SLC29A2 solute carrier family 29 member 2 2 2
MIRT468112 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT468733 SDC4 syndecan 4 2 2
MIRT469178 RNF111 ring finger protein 111 2 2
MIRT469577 RARA retinoic acid receptor alpha 2 2
MIRT470790 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT471177 PHB2 prohibitin 2 2 2
MIRT471325 PGAM4 phosphoglycerate mutase family member 4 2 2
MIRT471398 PDPR pyruvate dehydrogenase phosphatase regulatory subunit 2 2
MIRT471548 PAX5 paired box 5 2 2
MIRT471848 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT472229 NGFR nerve growth factor receptor 2 2
MIRT472548 NACC1 nucleus accumbens associated 1 2 2
MIRT473115 MLXIP MLX interacting protein 2 2
MIRT473212 MINK1 misshapen like kinase 1 2 2
MIRT473590 MAT2A methionine adenosyltransferase 2A 2 2
MIRT474184 LETMD1 LETM1 domain containing 1 2 2
MIRT474671 KLF13 Kruppel like factor 13 2 2
MIRT474854 KHSRP KH-type splicing regulatory protein 2 2
MIRT475152 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT475390 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT475587 HMGXB4 HMG-box containing 4 2 2
MIRT475773 HDLBP high density lipoprotein binding protein 2 2
MIRT477060 FAM210A family with sequence similarity 210 member A 2 2
MIRT477397 ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2 2
MIRT478335 DDN dendrin 2 2
MIRT478609 CTDSP2 CTD small phosphatase 2 2 3
MIRT479135 CNBP CCHC-type zinc finger nucleic acid binding protein 2 4
MIRT480106 CALR calreticulin 2 2
MIRT480416 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT480461 C11orf84 chromosome 11 open reading frame 84 2 4
MIRT481268 ATXN7L3 ataxin 7 like 3 2 2
MIRT481413 ASXL1 additional sex combs like 1, transcriptional regulator 2 2
MIRT481743 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT482159 AK2 adenylate kinase 2 2 2
MIRT482317 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT482398 AEN apoptosis enhancing nuclease 2 2
MIRT483346 CHRDL1 chordin like 1 2 8
MIRT483596 SLC26A9 solute carrier family 26 member 9 2 2
MIRT483634 NAV2 neuron navigator 2 2 2
MIRT483750 ALDH9A1 aldehyde dehydrogenase 9 family member A1 2 2
MIRT484085 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 4
MIRT484225 SUMO1 small ubiquitin-like modifier 1 2 6
MIRT484296 AIP aryl hydrocarbon receptor interacting protein 2 4
MIRT484374 GATA6 GATA binding protein 6 2 12
MIRT484395 ZNF710 zinc finger protein 710 2 4
MIRT484446 RAB7A RAB7A, member RAS oncogene family 2 4
MIRT484590 HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2 2
MIRT484626 SIX3 SIX homeobox 3 2 6
MIRT484737 ABCC6 ATP binding cassette subfamily C member 6 2 4
MIRT484861 ZNF70 zinc finger protein 70 2 4
MIRT486701 GLYR1 glyoxylate reductase 1 homolog 2 2
MIRT486803 PARP11 poly(ADP-ribose) polymerase family member 11 2 2
MIRT487059 C10orf55 chromosome 10 open reading frame 55 2 2
MIRT487077 CLASP1 cytoplasmic linker associated protein 1 2 4
MIRT487148 NCOR2 nuclear receptor corepressor 2 2 2
MIRT487625 C20orf96 chromosome 20 open reading frame 96 2 2
MIRT487710 CDK14 cyclin dependent kinase 14 2 2
MIRT487853 CLSTN1 calsyntenin 1 2 4
MIRT487970 IQSEC2 IQ motif and Sec7 domain 2 2 2
MIRT488138 GPR107 G protein-coupled receptor 107 2 2
MIRT488208 MAT1A methionine adenosyltransferase 1A 2 2
MIRT488363 PAX2 paired box 2 2 2
MIRT488593 ST7L suppression of tumorigenicity 7 like 2 2
MIRT488985 REXO2 RNA exonuclease 2 2 2
MIRT489068 STARD3 StAR related lipid transfer domain containing 3 2 2
MIRT489177 ANKRD45 ankyrin repeat domain 45 2 4
MIRT489327 GNB1L G protein subunit beta 1 like 2 2
MIRT489423 TUBB2A tubulin beta 2A class IIa 2 2
MIRT489808 KRT80 keratin 80 2 4
MIRT489868 ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 2 2
MIRT489922 RTKN rhotekin 2 2
MIRT490159 TMEM63C transmembrane protein 63C 2 2
MIRT490312 HOXB13 homeobox B13 2 2
MIRT490771 SRCIN1 SRC kinase signaling inhibitor 1 2 2
MIRT490904 BARHL1 BarH like homeobox 1 2 6
MIRT491072 ACVR1B activin A receptor type 1B 2 4
MIRT491242 KCNA5 potassium voltage-gated channel subfamily A member 5 2 2
MIRT491456 HOXB5 homeobox B5 2 2
MIRT492893 NFIX nuclear factor I X 2 2
MIRT492923 NFAT5 nuclear factor of activated T-cells 5 2 2
MIRT494021 DUSP9 dual specificity phosphatase 9 2 2
MIRT494046 DUSP7 dual specificity phosphatase 7 2 4
MIRT494190 CNOT6L CCR4-NOT transcription complex subunit 6 like 2 2
MIRT494721 ARHGAP31 Rho GTPase activating protein 31 2 2
MIRT494819 AKAP11 A-kinase anchoring protein 11 2 2
MIRT494909 UCP2 uncoupling protein 2 2 2
MIRT495262 CCDC108 cilia and flagella associated protein 65 2 2
MIRT495511 RGS6 regulator of G protein signaling 6 2 2
MIRT496604 TAGLN transgelin 2 2
MIRT498276 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT499031 MAG myelin associated glycoprotein 2 2
MIRT499816 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT500457 ZFP36L1 ZFP36 ring finger protein like 1 2 2
MIRT502340 GIGYF1 GRB10 interacting GYF protein 1 2 4
MIRT503646 POLR2F RNA polymerase II subunit F 2 4
MIRT508000 BCL2L13 BCL2 like 13 2 4
MIRT510802 SEPT2 septin 2 2 6
MIRT511040 NRF1 nuclear respiratory factor 1 2 2
MIRT512930 UBL4A ubiquitin like 4A 2 2
MIRT532005 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT539926 DUSP28 dual specificity phosphatase 28 2 2
MIRT553376 TRIM44 tripartite motif containing 44 2 2
MIRT568790 VPS37D VPS37D, ESCRT-I subunit 2 2
MIRT568827 TRIM67 tripartite motif containing 67 2 2
MIRT568876 LY6H lymphocyte antigen 6 family member H 2 2
MIRT568912 ATP6V1B1 ATPase H+ transporting V1 subunit B1 2 2
MIRT569993 TMEM184A transmembrane protein 184A 2 2
MIRT570225 SLC27A1 solute carrier family 27 member 1 2 2
MIRT570490 THRA thyroid hormone receptor, alpha 2 2
MIRT570541 RPH3A rabphilin 3A 2 2
MIRT570587 OTUD7B OTU deubiquitinase 7B 2 2
MIRT573681 HES6 hes family bHLH transcription factor 6 2 2
MIRT576457 Itga11 integrin alpha 11 2 3
MIRT608254 ITGA11 integrin subunit alpha 11 2 3
MIRT609751 FAM198A family with sequence similarity 198 member A 2 2
MIRT610860 ARSA arylsulfatase A 2 2
MIRT627528 SRP19 signal recognition particle 19 2 4
MIRT627895 OLFML2A olfactomedin like 2A 2 2
MIRT629785 PTDSS2 phosphatidylserine synthase 2 2 2
MIRT647051 C1QTNF6 C1q and TNF related 6 2 2
MIRT649532 GTF3C3 general transcription factor IIIC subunit 3 2 2
MIRT661455 MORC4 MORC family CW-type zinc finger 4 2 2
MIRT667859 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT668824 CYLD CYLD lysine 63 deubiquitinase 2 2
MIRT669492 ARL4C ADP ribosylation factor like GTPase 4C 2 2
MIRT670166 SLC29A4 solute carrier family 29 member 4 2 2
MIRT670929 DESI1 desumoylating isopeptidase 1 2 2
MIRT674655 NKRF NFKB repressing factor 2 2
MIRT681452 CIITA class II major histocompatibility complex transactivator 2 2
MIRT681766 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 2
MIRT682033 AGXT2 alanine--glyoxylate aminotransferase 2 2 4
MIRT684821 BRIX1 BRX1, biogenesis of ribosomes 2 2
MIRT686009 NEK4 NIMA related kinase 4 2 2
MIRT691758 IKBKG inhibitor of nuclear factor kappa B kinase subunit gamma 2 2
MIRT701938 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT702794 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT705706 ANKFY1 ankyrin repeat and FYVE domain containing 1 2 2
MIRT713377 STK35 serine/threonine kinase 35 2 2
MIRT714792 ATP6V1A ATPase H+ transporting V1 subunit A 2 2
MIRT715003 TSPAN11 tetraspanin 11 2 2
MIRT722688 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT755868 ITGA10 integrin subunit alpha 10 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4739 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4739 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4739 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (SW1990)
hsa-miR-4739 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (SW1990)
hsa-miR-4739 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4739 Cisplatin 5460033 NSC119875 approved resistant High Pancreatic Cancer cell line (BxPC-3)
hsa-miR-4739 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4739 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-mir-4739 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-mir-4739 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-miR-4739 Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-4739 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4739 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4739 Leuprorelin/Goserelin + Bicalutamide resistant tissue (prostate cancer)
hsa-miR-4739 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)

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