miRTarBase - #MIRT188328


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pre-miRNA Information
pre-miRNA hsa-mir-19b-2   
Genomic Coordinates chrX: 134169671 - 134169766
Synonyms MIRN19B2, miR-19b-2, MIR19B2
Description Homo sapiens miR-19b-2 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-19b-2-5p
Sequence 19| AGUUUUGCAGGUUUGCAUUUCA |40
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs747654746 3 dbSNP
rs778397250 5 dbSNP
rs754566533 6 dbSNP
rs749008511 12 dbSNP
rs779795647 17 dbSNP
rs755951722 18 dbSNP
rs193073651 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ARID1A   
Synonyms B120, BAF250, BAF250a, BM029, C1orf4, CSS2, ELD, MRD14, OSA1, P270, SMARCF1, hELD, hOSA1
Description AT-rich interaction domain 1A
Transcript NM_006015   
Other Transcripts NM_139135   
Expression
Putative miRNA Targets on ARID1A
3'UTR of ARID1A
(miRNA target sites are highlighted)		 
>ARID1A|NM_006015|3'UTR
   1 CAGCCGTGGGACACCTCCCCCCCCCGTGTGTGTGTGCGTGTGTGGAGAACTTAGAAACTGACTGTTGCCCTTTATTTATG
  81 CAAAACCACCTCAGAATCCAGTTTACCCTGTGCTGTCCAGCTTCTCCCTTGGGAAAAAGTCTCTCCTGTTTCTCTCTCCT
 161 CCTTCCACCTCCCCTCCCTCCATCACCTCACGCCTTTCTGTTCCTTGTCCTCACCTTACTCCCCTCAGGACCCTACCCCA
 241 CCCTCTTTGAAAAGACAAAGCTCTGCCTACATAGAAGACTTTTTTTATTTTAACCAAAGTTACTGTTGTTTACAGTGAGT
 321 TTGGGGAAAAAAAATAAAATAAAAATGGCTTTCCCAGTCCTTGCATCAACGGGATGCCACATTTCATAACTGTTTTTAAT
 401 GGTAAAAAAAAAAAAAAAAAATACAAAAAAAAATTCTGAAGGACAAAAAAGGTGACTGCTGAACTGTGTGTGGTTTATTG
 481 TTGTACATTCACAATCTTGCAGGAGCCAAGAAGTTCGCAGTTGTGAACAGACCCTGTTCACTGGAGAGGCCTGTGCAGTA
 561 GAGTGTAGACCCTTTCATGTACTGTACTGTACACCTGATACTGTAAACATACTGTAATAATAATGTCTCACATGGAAACA
 641 GAAAACGCTGGGTCAGCAGCAAGCTGTAGTTTTTAAAAATGTTTTTAGTTAAACGTTGAGGAGAAAAAAAAAAAAGGCTT
 721 TTCCCCCAAAGTATCATGTGTGAACCTACAACACCCTGACCTCTTTCTCTCCTCCTTGATTGTATGAATAACCCTGAGAT
 801 CACCTCTTAGAACTGGTTTTAACCTTTAGCTGCAGCGGCTACGCTGCCACGTGTGTATATATATGACGTTGTACATTGCA
 881 CATACCCTTGGATCCCCACAGTTTGGTCCTCCTCCCAGCTACCCCTTTATAGTATGACGAGTTAACAAGTTGGTGACCTG
 961 CACAAAGCGAGACACAGCTATTTAATCTCTTGCCAGATATCGCCCCTCTTGGTGCGATGCTGTACAGGTCTCTGTAAAAA
1041 GTCCTTGCTGTCTCAGCAGCCAATCAACTTATAGTTTATTTTTTTCTGGGTTTTTGTTTTGTTTTGTTTTCTTTCTAATC
1121 GAGGTGTGAAAAAGTTCTAGGTTCAGTTGAAGTTCTGATGAAGAAACACAATTGAGATTTTTTCAGTGATAAAATCTGCA
1201 TATTTGTATTTCAACAATGTAGCTAAAACTTGATGTAAATTCCTCCTTTTTTTCCTTTTTTGGCTTAATGAATATCATTT
1281 ATTCAGTATGAAATCTTTATACTATATGTTCCACGTGTTAAGAATAAATGTACATTAAATCTTGGTAAGACTTT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acuuuacguuuggACGUUUUGa 5'
                       |||||||| 
Target 5' tgccctttatttaTGCAAAACc 3'
 66 - 87 145.00 -7.30
2 
miRNA  3' acUUUAC-----GUUUGGA--CGUUUUGa 5'
            |||||     :|||:||  |:||:|| 
Target 5' atAAATGTACATTAAATCTTGGTAAGACt 3'
 1324 - 1352 134.00 -10.80
3 
miRNA  3' acuuUACGUUU--GGACGUUUUga 5'
              :| ||::  :|||:||||  
Target 5' tgctGTACAGGTCTCTGTAAAAag 3'
 1018 - 1041 120.00 -9.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1192736 6 ClinVar
1197106 11 ClinVar
COSN31594347 6 COSMIC
COSN30468855 18 COSMIC
COSN30552090 25 COSMIC
COSN30548382 26 COSMIC
COSN20074011 38 COSMIC
COSN30097813 93 COSMIC
COSN25846364 140 COSMIC
COSN31541229 196 COSMIC
COSN31596748 270 COSMIC
COSN30170887 271 COSMIC
COSN31594795 335 COSMIC
COSN19365852 422 COSMIC
COSN30174930 526 COSMIC
COSN22872902 608 COSMIC
COSN19304313 621 COSMIC
COSN28578908 675 COSMIC
COSN27402416 716 COSMIC
COSN29066575 716 COSMIC
COSN31769385 737 COSMIC
COSN31532324 811 COSMIC
COSN31513608 847 COSMIC
COSN31960201 852 COSMIC
COSN31535903 856 COSMIC
COSN31484548 970 COSMIC
COSN31556897 990 COSMIC
COSN31565426 1002 COSMIC
COSN26509054 1009 COSMIC
COSN26677618 1013 COSMIC
COSN31523204 1029 COSMIC
COSN31593976 1063 COSMIC
COSN31523201 1074 COSMIC
COSN31769386 1183 COSMIC
COSN31568545 1185 COSMIC
COSN31769390 1187 COSMIC
COSN31769393 1191 COSMIC
COSN32061019 1198 COSMIC
COSN31606438 1272 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs748607027 2 dbSNP
rs768407935 3 dbSNP
rs201289176 6 dbSNP
rs761262959 7 dbSNP
rs572794512 8 dbSNP
rs372029026 11 dbSNP
rs763359043 14 dbSNP
rs1371743129 16 dbSNP
rs1491421314 17 dbSNP
rs369896037 17 dbSNP
rs551176418 17 dbSNP
rs745390232 17 dbSNP
rs377238538 18 dbSNP
rs755516865 19 dbSNP
rs1263075449 21 dbSNP
rs774971536 21 dbSNP
rs377624643 22 dbSNP
rs760439531 22 dbSNP
rs763858866 23 dbSNP
rs778187938 23 dbSNP
rs200568725 24 dbSNP
rs776428236 24 dbSNP
rs1441882203 25 dbSNP
rs1491399260 25 dbSNP
rs201547182 26 dbSNP
rs3841356 26 dbSNP
rs750470371 26 dbSNP
rs199555039 27 dbSNP
rs1314517111 29 dbSNP
rs761352508 35 dbSNP
rs769273623 36 dbSNP
rs375168652 38 dbSNP
rs114615474 39 dbSNP
rs751971163 43 dbSNP
rs759773973 46 dbSNP
rs915071595 48 dbSNP
rs1387972191 55 dbSNP
rs994830363 59 dbSNP
rs1462055512 64 dbSNP
rs1328126265 69 dbSNP
rs1454399182 83 dbSNP
rs193200602 87 dbSNP
rs1028353479 99 dbSNP
rs1239740672 106 dbSNP
rs953605214 108 dbSNP
rs570966006 111 dbSNP
rs1288293349 113 dbSNP
rs1007771911 119 dbSNP
rs1264000698 129 dbSNP
rs1462893445 130 dbSNP
rs1019086140 134 dbSNP
rs965796800 140 dbSNP
rs1250317878 150 dbSNP
rs201874010 151 dbSNP
rs969224680 153 dbSNP
rs981247939 167 dbSNP
rs762599015 169 dbSNP
rs185013013 170 dbSNP
rs1479178017 179 dbSNP
rs1181304090 191 dbSNP
rs1205766877 192 dbSNP
rs751706703 193 dbSNP
rs1406403111 201 dbSNP
rs1470776155 204 dbSNP
rs989824139 207 dbSNP
rs377690379 213 dbSNP
rs928091627 217 dbSNP
rs939320870 220 dbSNP
rs1395579085 225 dbSNP
rs1036374197 233 dbSNP
rs868709218 234 dbSNP
rs1391892783 238 dbSNP
rs190650562 239 dbSNP
rs948598431 240 dbSNP
rs1408417706 241 dbSNP
rs1307887735 245 dbSNP
rs930879662 252 dbSNP
rs1235734781 255 dbSNP
rs1309946194 256 dbSNP
rs1320638749 263 dbSNP
rs928443330 266 dbSNP
rs757365605 268 dbSNP
rs566849047 269 dbSNP
rs1227680069 272 dbSNP
rs889275126 273 dbSNP
rs1481929277 275 dbSNP
rs766238144 280 dbSNP
rs939470085 280 dbSNP
rs1486603790 282 dbSNP
rs1044113 288 dbSNP
rs1223004626 300 dbSNP
rs1180113728 313 dbSNP
rs1411692272 320 dbSNP
rs1171345252 327 dbSNP
rs1284114092 327 dbSNP
rs369865650 327 dbSNP
rs1325901660 330 dbSNP
rs1392259519 331 dbSNP
rs550131155 331 dbSNP
rs1168337088 335 dbSNP
rs1376510290 336 dbSNP
rs897898640 342 dbSNP
rs1007749223 346 dbSNP
rs1301660848 353 dbSNP
rs1049058386 358 dbSNP
rs1382332074 360 dbSNP
rs144625506 371 dbSNP
rs1339653193 372 dbSNP
rs1481169558 375 dbSNP
rs1198014666 383 dbSNP
rs1187195724 387 dbSNP
rs1250042738 390 dbSNP
rs1188206844 391 dbSNP
rs1447878196 391 dbSNP
rs1396050280 393 dbSNP
rs1007784903 403 dbSNP
rs140784604 403 dbSNP
rs1174528243 404 dbSNP
rs1217268548 404 dbSNP
rs1372859595 404 dbSNP
rs531891434 404 dbSNP
rs533673675 404 dbSNP
rs71007893 404 dbSNP
rs71582803 404 dbSNP
rs879190726 404 dbSNP
rs1019140683 405 dbSNP
rs966221010 408 dbSNP
rs1429436211 413 dbSNP
rs1481204994 415 dbSNP
rs999017389 420 dbSNP
rs1188114808 421 dbSNP
rs140247425 422 dbSNP
rs879067977 423 dbSNP
rs1385781858 425 dbSNP
rs1424979331 425 dbSNP
rs201576837 425 dbSNP
rs957140373 425 dbSNP
rs990224567 425 dbSNP
rs1022551333 427 dbSNP
rs969962710 429 dbSNP
rs1036660091 437 dbSNP
rs981301637 438 dbSNP
rs1274019817 443 dbSNP
rs552617811 447 dbSNP
rs192390664 449 dbSNP
rs139737956 455 dbSNP
rs972587229 481 dbSNP
rs1303826808 482 dbSNP
rs919377839 485 dbSNP
rs1453530028 487 dbSNP
rs1219728139 489 dbSNP
rs1246460797 491 dbSNP
rs866265719 503 dbSNP
rs1184917444 509 dbSNP
rs1049101049 517 dbSNP
rs750577664 518 dbSNP
rs1164990786 520 dbSNP
rs1415411446 525 dbSNP
rs1295149514 534 dbSNP
rs1322530817 535 dbSNP
rs1030625284 540 dbSNP
rs1354846836 542 dbSNP
rs1411465866 557 dbSNP
rs1306038878 564 dbSNP
rs183673478 566 dbSNP
rs1230115951 572 dbSNP
rs1284851133 577 dbSNP
rs1264096542 578 dbSNP
rs943331229 578 dbSNP
rs1226801481 579 dbSNP
rs1289460947 580 dbSNP
rs1010767671 587 dbSNP
rs1207755836 588 dbSNP
rs1040674568 589 dbSNP
rs145352087 611 dbSNP
rs1189316316 615 dbSNP
rs1268970655 615 dbSNP
rs1471534613 619 dbSNP
rs1162241813 620 dbSNP
rs999468120 628 dbSNP
rs1431346731 629 dbSNP
rs1031799251 640 dbSNP
rs1260631745 647 dbSNP
rs1415289971 648 dbSNP
rs969606409 671 dbSNP
rs1336146483 675 dbSNP
rs1428849870 680 dbSNP
rs1342294407 685 dbSNP
rs1172224910 690 dbSNP
rs1445917538 694 dbSNP
rs892884880 695 dbSNP
rs573932625 696 dbSNP
rs1230974226 698 dbSNP
rs1272887783 699 dbSNP
rs1383216996 701 dbSNP
rs1423928995 702 dbSNP
rs1164141784 703 dbSNP
rs1011294855 704 dbSNP
rs1022606208 704 dbSNP
rs1212161198 704 dbSNP
rs760723895 704 dbSNP
rs1367469673 705 dbSNP
rs1428749539 720 dbSNP
rs969719142 736 dbSNP
rs981060933 737 dbSNP
rs1174211102 738 dbSNP
rs980644703 741 dbSNP
rs755982730 749 dbSNP
rs1333587077 751 dbSNP
rs779697055 762 dbSNP
rs1437514380 764 dbSNP
rs1295704549 766 dbSNP
rs972982682 766 dbSNP
rs960826442 768 dbSNP
rs546236808 770 dbSNP
rs1382588716 775 dbSNP
rs1343482452 778 dbSNP
rs749310830 781 dbSNP
rs1200457346 783 dbSNP
rs919252408 785 dbSNP
rs930659273 787 dbSNP
rs1465901163 794 dbSNP
rs1206385837 798 dbSNP
rs1454506677 804 dbSNP
rs930738590 804 dbSNP
rs1200715643 806 dbSNP
rs984895434 825 dbSNP
rs1477638772 833 dbSNP
rs985022973 835 dbSNP
rs910824315 838 dbSNP
rs943503949 842 dbSNP
rs1358365430 843 dbSNP
rs1388199644 844 dbSNP
rs1040553727 852 dbSNP
rs1303861925 856 dbSNP
rs902095027 860 dbSNP
rs900878195 864 dbSNP
rs1187969128 868 dbSNP
rs536545312 868 dbSNP
rs1052168297 869 dbSNP
rs1289548913 876 dbSNP
rs60798877 893 dbSNP
rs1226045973 895 dbSNP
rs1184076490 899 dbSNP
rs1010549686 901 dbSNP
rs1387049545 902 dbSNP
rs1488599804 905 dbSNP
rs1022141064 907 dbSNP
rs905118899 911 dbSNP
rs1264975363 912 dbSNP
rs893281882 914 dbSNP
rs778763188 915 dbSNP
rs1158452685 917 dbSNP
rs566545995 920 dbSNP
rs1414093032 922 dbSNP
rs1455533630 923 dbSNP
rs1473582132 928 dbSNP
rs1157021071 937 dbSNP
rs1411417459 939 dbSNP
rs1022699450 940 dbSNP
rs1388965067 944 dbSNP
rs1002408607 945 dbSNP
rs1334971301 947 dbSNP
rs1002535806 948 dbSNP
rs747678001 950 dbSNP
rs960857696 953 dbSNP
rs1352852079 960 dbSNP
rs572778412 969 dbSNP
rs1026425035 970 dbSNP
rs952002276 974 dbSNP
rs1246467690 975 dbSNP
rs1263340752 976 dbSNP
rs1355294489 979 dbSNP
rs1205622967 981 dbSNP
rs746879215 982 dbSNP
rs1317726068 996 dbSNP
rs1375287195 998 dbSNP
rs12685 999 dbSNP
rs1181420844 1000 dbSNP
rs1249887927 1002 dbSNP
rs1424496245 1003 dbSNP
rs910760044 1004 dbSNP
rs994071818 1005 dbSNP
rs1027296882 1009 dbSNP
rs943634804 1014 dbSNP
rs976778050 1016 dbSNP
rs1408513780 1023 dbSNP
rs188298594 1026 dbSNP
rs1460677655 1042 dbSNP
rs985282134 1046 dbSNP
rs1244800396 1051 dbSNP
rs923453125 1053 dbSNP
rs1310061934 1061 dbSNP
rs1339498312 1064 dbSNP
rs1468526124 1067 dbSNP
rs772969127 1073 dbSNP
rs1276480547 1078 dbSNP
rs1339867681 1078 dbSNP
rs964750452 1081 dbSNP
rs36117735 1086 dbSNP
rs1256548522 1087 dbSNP
rs747724215 1092 dbSNP
rs976087309 1092 dbSNP
rs1408722599 1105 dbSNP
rs1420966563 1110 dbSNP
rs1174480077 1111 dbSNP
rs1428252222 1112 dbSNP
rs528990173 1113 dbSNP
rs934925108 1115 dbSNP
rs1470448228 1121 dbSNP
rs760232227 1122 dbSNP
rs1299399036 1127 dbSNP
rs548634719 1131 dbSNP
rs544354417 1138 dbSNP
rs1301827326 1143 dbSNP
rs1313870762 1144 dbSNP
rs914796227 1146 dbSNP
rs1254308225 1158 dbSNP
rs762673189 1160 dbSNP
rs558794605 1166 dbSNP
rs1044541667 1169 dbSNP
rs555311641 1170 dbSNP
rs1280862191 1173 dbSNP
rs1322377873 1178 dbSNP
rs1426400378 1178 dbSNP
rs1435396043 1184 dbSNP
rs1223811004 1192 dbSNP
rs1264768228 1196 dbSNP
rs147234817 1201 dbSNP
rs1322061358 1216 dbSNP
rs904897761 1218 dbSNP
rs994223697 1218 dbSNP
rs1002119988 1219 dbSNP
rs1035378243 1223 dbSNP
rs1293862975 1224 dbSNP
rs567162533 1230 dbSNP
rs1481632983 1236 dbSNP
rs1197324707 1241 dbSNP
rs1322828742 1243 dbSNP
rs1229101269 1246 dbSNP
rs756317726 1246 dbSNP
rs866177135 1246 dbSNP
rs1463707738 1247 dbSNP
rs1428741691 1255 dbSNP
rs1480877517 1256 dbSNP
rs952603391 1259 dbSNP
rs1489685103 1260 dbSNP
rs1178860619 1263 dbSNP
rs1417742913 1264 dbSNP
rs1409773858 1265 dbSNP
rs1429209967 1266 dbSNP
rs537890755 1267 dbSNP
rs180769241 1269 dbSNP
rs1356760783 1273 dbSNP
rs1399732242 1275 dbSNP
rs77103907 1279 dbSNP
rs1165063956 1285 dbSNP
rs1351360742 1289 dbSNP
rs1434029488 1297 dbSNP
rs1018085560 1298 dbSNP
rs964802993 1298 dbSNP
rs1411656473 1305 dbSNP
rs547256040 1307 dbSNP
rs1300734152 1308 dbSNP
rs1290258585 1312 dbSNP
rs1327225341 1314 dbSNP
rs1223384334 1315 dbSNP
rs896302585 1316 dbSNP
rs1323815558 1329 dbSNP
rs976141554 1345 dbSNP
rs923333401 1349 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' acuuuacguuuggACGUUUUGa 5'
                       |||||||| 
Target 5' --cccuuuauuuaUGCAAAACc 3'
 		1 - 20
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000324856.7 | 3UTR | CCCUUUAUUUAUGCAAAACCACCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000324856.7 | 3UTR | CCCUUUAUUUAUGCAAAACCAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla 0.782 7.9e-4 0.648 8.3e-3 13 Click to see details
GSE28544 Breast cancer 0.353 4.5e-2 0.376 3.5e-2 24 Click to see details
GSE38226 Liver fibrosis 0.366 5.1e-2 0.394 3.9e-2 21 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.266 9.9e-2 0.230 1.3e-1 25 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.244 1.5e-1 0.626 1.6e-3 20 Click to see details
GSE26953 Aortic valvular endothelial cells -0.212 1.6e-1 -0.219 1.5e-1 24 Click to see details
GSE21687 Ependynoma primary tumors -0.122 1.7e-1 -0.014 4.6e-1 64 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.163 2.2e-1 0.395 2.5e-2 25 Click to see details
GSE15076 Monocyte-derived dendritic cells -0.291 2.2e-1 -0.317 2.0e-1 9 Click to see details
GSE19350 CNS germ cell tumors -0.239 2.3e-1 0.028 4.7e-1 12 Click to see details
GSE32688 Pancreatic cancer 0.131 2.4e-1 0.154 2.0e-1 32 Click to see details
GSE17498 Multiple myeloma -0.074 3.2e-1 0.060 3.6e-1 40 Click to see details
GSE42095 Differentiated embryonic stem cells -0.062 3.9e-1 -0.185 2.0e-1 23 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
-0.062 3.9e-1 -0.185 2.0e-1 23 Click to see details
-0.062 3.9e-1 -0.185 2.0e-1 23 Click to see details
93 hsa-miR-19b-2-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT063866 RASSF8 Ras association domain family member 8 2 6
MIRT077658 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 2
MIRT078463 MAP3K3 mitogen-activated protein kinase kinase kinase 3 2 2
MIRT095250 FAM13B family with sequence similarity 13 member B 2 2
MIRT109492 KLHL15 kelch like family member 15 2 6
MIRT155380 CCNT2 cyclin T2 2 2
MIRT163210 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 2
MIRT188328 ARID1A AT-rich interaction domain 1A 2 2
MIRT204725 BZW1 basic leucine zipper and W2 domains 1 2 4
MIRT236401 HMGXB4 HMG-box containing 4 2 2
MIRT237116 P2RY1 purinergic receptor P2Y1 2 5
MIRT286944 SOCS7 suppressor of cytokine signaling 7 2 2
MIRT438799 MYC MYC proto-oncogene, bHLH transcription factor 1 1
MIRT442521 MOB3B MOB kinase activator 3B 2 2
MIRT452256 RPL30 ribosomal protein L30 2 2
MIRT473426 MDM4 MDM4, p53 regulator 2 2
MIRT476781 FOS Fos proto-oncogene, AP-1 transcription factor subunit 2 2
MIRT476940 FAM83G family with sequence similarity 83 member G 2 2
MIRT480182 CALM2 calmodulin 2 2 6
MIRT489618 ZNF384 zinc finger protein 384 2 2
MIRT492244 SLC39A9 solute carrier family 39 member 9 2 2
MIRT492420 RGL2 ral guanine nucleotide dissociation stimulator like 2 2 2
MIRT494858 ZNF99 zinc finger protein 99 2 2
MIRT496999 SNAP25 synaptosome associated protein 25 2 2
MIRT501971 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT504915 CD38 CD38 molecule 2 4
MIRT507017 HMGA2 high mobility group AT-hook 2 2 6
MIRT510818 SBNO1 strawberry notch homolog 1 2 4
MIRT514164 PGPEP1 pyroglutamyl-peptidase I 2 2
MIRT514326 PSMG2 proteasome assembly chaperone 2 2 4
MIRT514427 SLC38A7 solute carrier family 38 member 7 2 2
MIRT514534 ESR2 estrogen receptor 2 2 2
MIRT516115 SRPX2 sushi repeat containing protein, X-linked 2 2 4
MIRT517757 ZNF366 zinc finger protein 366 2 4
MIRT518493 FAM161B family with sequence similarity 161 member B 2 4
MIRT518510 CASP10 caspase 10 2 2
MIRT518559 GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 2 2
MIRT518639 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT518727 ABCG8 ATP binding cassette subfamily G member 8 2 2
MIRT523562 GGCX gamma-glutamyl carboxylase 2 4
MIRT526521 YIPF6 Yip1 domain family member 6 2 2
MIRT530252 ZNF620 zinc finger protein 620 2 2
MIRT531656 ZFP14 ZFP14 zinc finger protein 2 2
MIRT532697 TCN2 transcobalamin 2 2 4
MIRT534017 STXBP4 syntaxin binding protein 4 2 2
MIRT535746 MYO10 myosin X 2 4
MIRT544507 GTF2E2 general transcription factor IIE subunit 2 2 2
MIRT546756 RLIM ring finger protein, LIM domain interacting 2 2
MIRT547927 HNRNPR heterogeneous nuclear ribonucleoprotein R 2 2
MIRT550128 ZNF138 zinc finger protein 138 2 2
MIRT551761 MED21 mediator complex subunit 21 2 2
MIRT557725 FYCO1 FYVE and coiled-coil domain containing 1 2 2
MIRT558922 CBX1 chromobox 1 2 2
MIRT562464 CORO1C coronin 1C 2 2
MIRT562757 ZNF846 zinc finger protein 846 2 2
MIRT563059 ZNF28 zinc finger protein 28 2 2
MIRT563334 RPLP0 ribosomal protein lateral stalk subunit P0 2 2
MIRT569168 DMD dystrophin 2 2
MIRT573253 TNFAIP6 TNF alpha induced protein 6 2 2
MIRT575055 P2ry1 purinergic receptor P2Y, G-protein coupled 1 2 4
MIRT575358 Zxda zinc finger, X-linked, duplicated A 2 2
MIRT613231 CCDC39 coiled-coil domain containing 39 2 2
MIRT613345 ADRBK2 G protein-coupled receptor kinase 3 2 6
MIRT613950 TMEM59 transmembrane protein 59 2 2
MIRT615486 EDN1 endothelin 1 2 2
MIRT618708 ESD esterase D 2 2
MIRT630607 ARHGAP1 Rho GTPase activating protein 1 2 2
MIRT630617 CXCR6 C-X-C motif chemokine receptor 6 2 2
MIRT630629 IMPAD1 inositol monophosphatase domain containing 1 2 2
MIRT630672 KLF7 Kruppel like factor 7 2 2
MIRT630744 COG6 component of oligomeric golgi complex 6 2 2
MIRT636851 ZSCAN2 zinc finger and SCAN domain containing 2 2 2
MIRT638640 GPATCH8 G-patch domain containing 8 2 2
MIRT639104 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT639420 PKP1 plakophilin 1 2 2
MIRT640185 ABCC12 ATP binding cassette subfamily C member 12 2 2
MIRT641755 SF3A1 splicing factor 3a subunit 1 2 2
MIRT666575 RHOBTB3 Rho related BTB domain containing 3 2 2
MIRT672164 FANCF Fanconi anemia complementation group F 2 2
MIRT688343 ETS1 ETS proto-oncogene 1, transcription factor 2 2
MIRT690118 ZFAND1 zinc finger AN1-type containing 1 2 2
MIRT696937 CERK ceramide kinase 2 2
MIRT701359 NR4A3 nuclear receptor subfamily 4 group A member 3 2 2
MIRT703286 GID4 GID complex subunit 4 homolog 2 2
MIRT709144 ZNF799 zinc finger protein 799 2 2
MIRT710846 FAM210A family with sequence similarity 210 member A 2 2
MIRT712619 GTF2H5 general transcription factor IIH subunit 5 2 2
MIRT714589 CMBL carboxymethylenebutenolidase homolog 2 2
MIRT716907 CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 2 2
MIRT721163 FAM200B family with sequence similarity 200 member B 2 2
MIRT722401 BCAS2 BCAS2, pre-mRNA processing factor 2 2
MIRT722515 DSTYK dual serine/threonine and tyrosine protein kinase 2 2
MIRT724597 AP3B1 adaptor related protein complex 3 beta 1 subunit 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-19b-2 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-miR-19b-2-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-19b-2-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-19b-2-5p Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-miR-19b-2-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-19b-2-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (TamR4)
hsa-miR-19b-2-5p Tamoxifen 2733525 NSC180973 approved resistant cell line (TamR8)
hsa-miR-19b-2-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-19b-2-5p Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)

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