miRTarBase - #MIRT189772


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pre-miRNA Information
pre-miRNA hsa-mir-4665   
Genomic Coordinates chr9: 6007826 - 6007904
Description Homo sapiens miR-4665 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4665-5p
Sequence 10| CUGGGGGACGCGUGAGCGCGAGC |32
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs901542342 1 dbSNP
rs1170299887 2 dbSNP
rs747546692 3 dbSNP
rs1260840238 4 dbSNP
rs1377576716 5 dbSNP
rs1349863083 6 dbSNP
rs933050749 7 dbSNP
rs1236802314 11 dbSNP
rs1050148325 12 dbSNP
rs1198393802 14 dbSNP
rs771241090 19 dbSNP
rs1258201615 20 dbSNP
rs1485839367 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CDADC1   
Synonyms NYD-SP15, bA103J18.1
Description cytidine and dCMP deaminase domain containing 1
Transcript NM_030911   
Expression
Putative miRNA Targets on CDADC1
3'UTR of CDADC1
(miRNA target sites are highlighted)		 
>CDADC1|NM_030911|3'UTR
   1 GAAGGCCTGTCTACACTGCAGGGGAACCTCAAGAACTTTTCATTGCACTTCTAAAATTCAGCCTTGTTCATTCAGAAAAT
  81 AAGGATGGATTTTGTGAATAATTGAAAAGATTTTTTAAGGAAGCTAATTTATTTCTAGGATACAAATGGTGTTAATAAGA
 161 ATATTTGTCTTTTAGATTTATGTGTGGGTTTTCCATAATGTAGTAGTGTGTTATTTTATTACACGAAATGAGGGAGCAAT
 241 AACTTCAACCAATGTAATCACCAACAGGGACTGATTTCTATTTATCTTGACTTTATATTAGCCAATTTGAAAGGGTCTGC
 321 TTCACAAGAGGTCATGCCTCTGCAGGGAATCACACACCTTTTGAGAAATATTAATTCTTTTGAATTACAAGAGTGACAGT
 401 TAGTAAACTGCTCCAGGGAAATAAGTGTCATCTTTTAAGAGTCAGTGTATAGCAAACCAAAAGATCACATTTATACCCAA
 481 AGCTTTCTAGTAATCAGAATTTACTTAATTAGAATTGACTCATAAAAATAAAGTTAGTGGACTTTGTCTCCATTTTTAAA
 561 GTATATTTTGTAAATGTTAATTCTGTGGTCCTGTTTATCACAGACTTTGGGTAGCAATAGGAAGAGAGTGTTATTCTGAG
 641 ACAGTGTCGCTGCTTGATATCACTGACTCTTGAAATCACTAACAGTGAACCTCAAATTTGGTTATGATGTTAACAGAGAA
 721 GAAATATTTGAGTCTGGAATATTGAAACTAGCTTTCCTAGAATTCCATTAATAAATGCTGCTCCCCCATATAGTCTTCCC
 801 TTCTGTATAATTAACATAGGTTGTCTCATGGCTTTGATCTTCAAAAGGAAGAGCCTTTTAAAAACATTTGCCAACCTCAA
 881 GAATAAATACTGAAAGTCTTGAAAGTATGGTCATTTCAGCTATTCCAGATTGCTGTCTGTGATTTCTCACATTTTTATTT
 961 GCTGAGAAACATTCAGAAAATTATTCCAAAAATGAAGGTACATTTTCTGTTCTCTCCTAGGTTAGAGAGGGGTGGCCTGG
1041 GGTGCTTCATGAGAAATGTCTTCCTGGATCTGCGGTGGTCAGGTTTGCCTCTGCTTTTGTTCCCTGCCTTTCCGCCACAT
1121 CACACGGCCTCACTGGGCTTCCTACCAGTTTCTCAGAATTACACGCACGACCATCCAAACATTGGCTCCATGCCAGGGCT
1201 GTGACTGCAGCCTGTGTAGGACCATGGGGAGTTCAGAGTCATCATACAAGGCAGCCAAGAACTGCCATAAACACTACACA
1281 GATGGAGGGCATGGGATAGGACAGGAGAGGAGGTGATGTACACTTAGAGGTAACTAAGGCTAGTTTGAAAACCGTGAATT
1361 AAGATATTCTTATCAGTATAAAAACACTGAGATTGCTTACCTCCCAAATTGCTTTATTGTATTAACTCTCATGCTTCAGC
1441 TCTTGGATTTGTTGTTTCTAACTAACATGTCATGTACACCAAACATTTTATAAATCAATCAGTAAATATTTTGTAAGACC
1521 CAAAATCCTGGCATATTGCCAGGTCTGTGGATTTGCCTGTTGGGTGTTGGGATGGGATATCAGAGGAAGAAGCATACAAG
1601 TGGGAAAAACTGTGATTAGAAAGGGAAAAATAGGCATTTCCACAGTACTATTAAGAGAGGCATGATAATGCCATTTTTTT
1681 TCTTCTGTACAACTGGTCAGATTTCAATAAATAATCATTGATGGTTTACAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgagcGCGAGUGCGCAGGGGGUc 5'
               :|||   || ||||||| 
Target 5' ataaaTGCT---GC-TCCCCCAt 3'
 771 - 789 146.00 -17.10
2 
miRNA  3' cgAGCGCGAGUG-CG--CAGGGGGUc 5'
            |: :|:|| | ||   ||| ||| 
Target 5' gcTTTTGTTCCCTGCCTTTCCGCCAc 3'
 1093 - 1118 119.00 -15.80
3 
miRNA  3' cgaGCGCGAGUG---CGCAGGG-GGUc 5'
             ||  |||||   || |||: ||| 
Target 5' acaCGGCCTCACTGGGCTTCCTACCAg 3'
 1122 - 1148 116.00 -19.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31559668 11 COSMIC
COSN31555507 43 COSMIC
COSN30165763 64 COSMIC
COSN30449056 91 COSMIC
COSN31542132 110 COSMIC
COSN6230729 257 COSMIC
COSN15653961 430 COSMIC
COSN31546433 585 COSMIC
COSN26604165 650 COSMIC
COSN28757256 650 COSMIC
COSN14907609 798 COSMIC
COSN31591510 833 COSMIC
COSN26642667 963 COSMIC
COSN28692867 977 COSMIC
COSN28863181 1043 COSMIC
COSN26553698 1078 COSMIC
COSN14441762 1166 COSMIC
COSN20066337 1206 COSMIC
COSN32057939 1398 COSMIC
COSN28198284 1539 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1311992692 6 dbSNP
rs1336365936 12 dbSNP
rs755981874 16 dbSNP
rs779925000 17 dbSNP
rs748410476 19 dbSNP
rs1333907742 24 dbSNP
rs377589344 27 dbSNP
rs1308799901 34 dbSNP
rs1214768118 38 dbSNP
rs1259865655 40 dbSNP
rs142678078 47 dbSNP
rs988081665 48 dbSNP
rs747156666 52 dbSNP
rs762360524 74 dbSNP
rs1324183476 79 dbSNP
rs534506125 80 dbSNP
rs879211185 82 dbSNP
rs1463058458 85 dbSNP
rs765706117 86 dbSNP
rs186902156 87 dbSNP
rs1158561250 96 dbSNP
rs1452181621 100 dbSNP
rs568242673 103 dbSNP
rs1417555752 106 dbSNP
rs535336791 111 dbSNP
rs979171400 111 dbSNP
rs1266194913 122 dbSNP
rs1191417013 130 dbSNP
rs1158763243 134 dbSNP
rs927396789 141 dbSNP
rs1019266849 144 dbSNP
rs965431957 147 dbSNP
rs1207569438 150 dbSNP
rs977156598 152 dbSNP
rs937459401 154 dbSNP
rs1457593857 157 dbSNP
rs556851976 158 dbSNP
rs1025719722 170 dbSNP
rs1262489670 171 dbSNP
rs1239461306 175 dbSNP
rs532470471 178 dbSNP
rs951475874 183 dbSNP
rs1330352020 186 dbSNP
rs1382124849 188 dbSNP
rs1322417087 195 dbSNP
rs1372007782 206 dbSNP
rs984132999 206 dbSNP
rs910074755 208 dbSNP
rs1057215006 209 dbSNP
rs1387776925 218 dbSNP
rs1159696454 219 dbSNP
rs948208331 223 dbSNP
rs190171227 225 dbSNP
rs928201562 226 dbSNP
rs940880728 232 dbSNP
rs183498275 234 dbSNP
rs1284269424 237 dbSNP
rs1253299780 244 dbSNP
rs899420531 245 dbSNP
rs1380762479 246 dbSNP
rs112223911 254 dbSNP
rs1263734297 265 dbSNP
rs994474815 270 dbSNP
rs539050465 273 dbSNP
rs1344258719 275 dbSNP
rs1029115965 276 dbSNP
rs1052538180 281 dbSNP
rs892097164 283 dbSNP
rs1428690993 293 dbSNP
rs946467589 294 dbSNP
rs1008681616 298 dbSNP
rs572422893 301 dbSNP
rs188396396 304 dbSNP
rs888980478 306 dbSNP
rs1315159062 316 dbSNP
rs564821556 320 dbSNP
rs1287343712 321 dbSNP
rs988395152 330 dbSNP
rs1395276551 331 dbSNP
rs758752121 353 dbSNP
rs968406216 356 dbSNP
rs1193282063 358 dbSNP
rs901751207 359 dbSNP
rs1255391403 378 dbSNP
rs993395671 394 dbSNP
rs1261751066 398 dbSNP
rs1025605066 404 dbSNP
rs951362203 409 dbSNP
rs1341776483 411 dbSNP
rs1442339249 417 dbSNP
rs1270784945 422 dbSNP
rs1367728481 426 dbSNP
rs9535193 430 dbSNP
rs1016953597 432 dbSNP
rs1354106872 448 dbSNP
rs937407110 450 dbSNP
rs1415756450 461 dbSNP
rs541250106 465 dbSNP
rs1327305369 478 dbSNP
rs917343889 483 dbSNP
rs751788277 487 dbSNP
rs1167977836 491 dbSNP
rs1413017424 500 dbSNP
rs1474633882 503 dbSNP
rs1415544598 508 dbSNP
rs928117728 513 dbSNP
rs940828451 522 dbSNP
rs193202729 525 dbSNP
rs1161122164 531 dbSNP
rs1439758543 549 dbSNP
rs988386302 554 dbSNP
rs74074527 558 dbSNP
rs1332828799 560 dbSNP
rs542509509 570 dbSNP
rs1234393403 575 dbSNP
rs563982490 581 dbSNP
rs910301949 588 dbSNP
rs781396977 590 dbSNP
rs930926097 594 dbSNP
rs530923679 599 dbSNP
rs552641948 600 dbSNP
rs1391593832 604 dbSNP
rs146945581 606 dbSNP
rs901639610 608 dbSNP
rs1407235606 615 dbSNP
rs1350739319 616 dbSNP
rs748277629 618 dbSNP
rs1229908865 620 dbSNP
rs1040120584 621 dbSNP
rs1193186467 626 dbSNP
rs1047611735 627 dbSNP
rs1344802486 631 dbSNP
rs1220295405 649 dbSNP
rs867795798 650 dbSNP
rs1009397773 653 dbSNP
rs1482094494 655 dbSNP
rs1204534739 658 dbSNP
rs1225800458 663 dbSNP
rs1351914828 672 dbSNP
rs1274657663 678 dbSNP
rs770895956 685 dbSNP
rs1022580221 693 dbSNP
rs564405326 696 dbSNP
rs1156894386 708 dbSNP
rs1402396676 715 dbSNP
rs528612398 715 dbSNP
rs1033574799 719 dbSNP
rs1172787198 721 dbSNP
rs1017006134 734 dbSNP
rs1197582067 741 dbSNP
rs1194335487 752 dbSNP
rs778773764 753 dbSNP
rs1002252629 760 dbSNP
rs1240843610 762 dbSNP
rs917292929 779 dbSNP
rs1173049367 783 dbSNP
rs1035614410 789 dbSNP
rs1448114751 791 dbSNP
rs962478044 804 dbSNP
rs1427185438 805 dbSNP
rs1345282304 807 dbSNP
rs1305226029 808 dbSNP
rs1219279297 826 dbSNP
rs1360601237 827 dbSNP
rs1427198657 831 dbSNP
rs1286641634 833 dbSNP
rs1432725714 843 dbSNP
rs1345728460 855 dbSNP
rs1397086973 856 dbSNP
rs1167398093 870 dbSNP
rs960876368 875 dbSNP
rs1174553565 891 dbSNP
rs1411243273 904 dbSNP
rs988420297 906 dbSNP
rs1417419002 914 dbSNP
rs972251115 920 dbSNP
rs546800284 932 dbSNP
rs11616334 936 dbSNP
rs1257507659 951 dbSNP
rs566762566 952 dbSNP
rs1486884327 962 dbSNP
rs373254567 968 dbSNP
rs1254087960 975 dbSNP
rs3751418 977 dbSNP
rs1160403847 994 dbSNP
rs1380130599 999 dbSNP
rs1418221528 1002 dbSNP
rs1156530502 1004 dbSNP
rs775295799 1009 dbSNP
rs57894843 1010 dbSNP
rs1301762313 1012 dbSNP
rs1306563978 1014 dbSNP
rs1376297330 1014 dbSNP
rs777253561 1015 dbSNP
rs1249542732 1025 dbSNP
rs910186981 1030 dbSNP
rs1341049428 1032 dbSNP
rs1437666497 1040 dbSNP
rs1223219043 1043 dbSNP
rs539038160 1045 dbSNP
rs746316772 1047 dbSNP
rs1375958769 1050 dbSNP
rs1237667014 1051 dbSNP
rs557770151 1064 dbSNP
rs1348874919 1068 dbSNP
rs775794500 1073 dbSNP
rs538319347 1074 dbSNP
rs760273608 1075 dbSNP
rs768393423 1076 dbSNP
rs1040067159 1082 dbSNP
rs929144885 1083 dbSNP
rs1047675063 1090 dbSNP
rs1429234133 1103 dbSNP
rs1266974183 1104 dbSNP
rs768347527 1114 dbSNP
rs1450756209 1119 dbSNP
rs1258609410 1121 dbSNP
rs776091119 1122 dbSNP
rs1177011663 1126 dbSNP
rs887685576 1127 dbSNP
rs1249300882 1132 dbSNP
rs754684674 1134 dbSNP
rs1206000752 1139 dbSNP
rs1318070268 1140 dbSNP
rs1272001627 1150 dbSNP
rs761298661 1152 dbSNP
rs941916539 1166 dbSNP
rs1447576969 1169 dbSNP
rs1187897068 1174 dbSNP
rs1390650807 1182 dbSNP
rs1371410961 1190 dbSNP
rs1300180822 1206 dbSNP
rs1466352860 1210 dbSNP
rs1393747210 1211 dbSNP
rs1162919173 1215 dbSNP
rs533860175 1217 dbSNP
rs1009757735 1246 dbSNP
rs1038334627 1247 dbSNP
rs1419271335 1264 dbSNP
rs1431127735 1268 dbSNP
rs905168120 1271 dbSNP
rs1161053323 1272 dbSNP
rs1389575846 1275 dbSNP
rs530292773 1279 dbSNP
rs1406264227 1290 dbSNP
rs555188723 1295 dbSNP
rs1178516924 1312 dbSNP
rs1457936888 1319 dbSNP
rs1325931070 1321 dbSNP
rs1002711397 1322 dbSNP
rs1211302279 1339 dbSNP
rs1336823158 1355 dbSNP
rs1035097940 1356 dbSNP
rs1238050749 1365 dbSNP
rs1314855299 1366 dbSNP
rs1308890956 1367 dbSNP
rs1363512734 1368 dbSNP
rs7993195 1370 dbSNP
rs1299016734 1373 dbSNP
rs747703182 1385 dbSNP
rs1392076884 1391 dbSNP
rs1021252114 1395 dbSNP
rs3087770 1398 dbSNP
rs532608573 1400 dbSNP
rs1365841112 1404 dbSNP
rs1449778509 1407 dbSNP
rs1242705444 1413 dbSNP
rs1439870518 1413 dbSNP
rs1394147717 1417 dbSNP
rs1191167865 1422 dbSNP
rs1469468971 1424 dbSNP
rs1265024438 1426 dbSNP
rs1357302714 1433 dbSNP
rs1267461242 1435 dbSNP
rs1484872548 1439 dbSNP
rs1262225475 1443 dbSNP
rs979642260 1452 dbSNP
rs563960215 1473 dbSNP
rs1274783727 1475 dbSNP
rs964382769 1476 dbSNP
rs1207979056 1480 dbSNP
rs1317729973 1483 dbSNP
rs1014207032 1486 dbSNP
rs1024294025 1498 dbSNP
rs1299160110 1499 dbSNP
rs1434527505 1501 dbSNP
rs879585786 1512 dbSNP
rs552402229 1520 dbSNP
rs923040272 1522 dbSNP
rs929173861 1523 dbSNP
rs983254714 1524 dbSNP
rs1377661716 1527 dbSNP
rs746993995 1528 dbSNP
rs1191877731 1529 dbSNP
rs1426641371 1542 dbSNP
rs1263820400 1544 dbSNP
rs1217061543 1545 dbSNP
rs779385715 1563 dbSNP
rs1184800015 1565 dbSNP
rs1277942004 1569 dbSNP
rs1213204983 1576 dbSNP
rs909009805 1580 dbSNP
rs941970205 1582 dbSNP
rs1269618064 1584 dbSNP
rs1367446479 1586 dbSNP
rs1044290632 1589 dbSNP
rs1328673549 1590 dbSNP
rs1279455943 1597 dbSNP
rs905221145 1617 dbSNP
rs938008406 1622 dbSNP
rs1056989883 1631 dbSNP
rs952284253 1632 dbSNP
rs1415776561 1644 dbSNP
rs896562242 1645 dbSNP
rs1413416358 1660 dbSNP
rs1402535291 1673 dbSNP
rs185529714 1674 dbSNP
rs986308450 1674 dbSNP
rs1425671978 1680 dbSNP
rs1460087379 1680 dbSNP
rs1386844784 1683 dbSNP
rs1457070637 1686 dbSNP
rs1321728030 1688 dbSNP
rs1391486341 1693 dbSNP
rs1194222697 1701 dbSNP
rs910771684 1706 dbSNP
rs1255086533 1712 dbSNP
rs1021137723 1717 dbSNP
rs1443191036 1720 dbSNP
rs1272610225 1723 dbSNP
rs1194143121 1725 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgagcGCGAGUGCGCAGGGgguc 5'
               :|||   || ||||    
Target 5' auaaaUGCU---GC-UCCC---- 3'
 		11 - 25
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_030911 | 3UTR | GAGUCUGGAAUAUUGAAACUAGCUUUCCUAGAAUUCCAUUAAUAAAUGCUGCUCCCCCAUAUAGUCUUCCCUUCUGUAUAAUUAACAUAGGUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_030911 | 3UTR | AUGCUGCUCCCCCAUAUAGUCUUCCCUUCUGUAUAAUUAACAUAGGUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM545214
Method / RBP PAR-CLIP / AGO3
Cell line / Condition HEK293 / Control
Location of target site ENST00000251108.6 | 3UTR | AAUUCCAUUAAUAAAUGCUGCUCCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
123 hsa-miR-4665-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT115350 IGF1R insulin like growth factor 1 receptor 2 8
MIRT144387 SF3B3 splicing factor 3b subunit 3 2 2
MIRT145421 ANKRD13B ankyrin repeat domain 13B 2 4
MIRT146684 MINK1 misshapen like kinase 1 2 2
MIRT178944 C11ORF57 chromosome 11 open reading frame 57 2 2
MIRT189772 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT238514 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2 2
MIRT366308 GDI1 GDP dissociation inhibitor 1 2 4
MIRT375173 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 2
MIRT442321 WNT9B Wnt family member 9B 2 2
MIRT442581 HOXD9 homeobox D9 2 2
MIRT451170 PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 2 2
MIRT451894 ILK integrin linked kinase 2 2
MIRT453620 SLC4A2 solute carrier family 4 member 2 2 2
MIRT454769 STOML3 stomatin like 3 2 2
MIRT455038 MEN1 menin 1 2 2
MIRT455151 SUV39H1 suppressor of variegation 3-9 homolog 1 2 2
MIRT456891 DDA1 DET1 and DDB1 associated 1 2 2
MIRT457201 THSD4 thrombospondin type 1 domain containing 4 2 2
MIRT457373 CAMK2A calcium/calmodulin dependent protein kinase II alpha 2 2
MIRT459190 RCE1 Ras converting CAAX endopeptidase 1 2 2
MIRT462580 MYL12A myosin light chain 12A 2 2
MIRT464669 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT464753 UBE2N ubiquitin conjugating enzyme E2 N 2 2
MIRT464881 UBALD1 UBA like domain containing 1 2 2
MIRT465932 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466013 TMEM189 transmembrane protein 189 2 2
MIRT466905 STK38 serine/threonine kinase 38 2 10
MIRT468421 SETD1B SET domain containing 1B 2 2
MIRT468592 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT468853 RREB1 ras responsive element binding protein 1 2 2
MIRT468900 RPS6KA4 ribosomal protein S6 kinase A4 2 2
MIRT469189 RICTOR RPTOR independent companion of MTOR complex 2 2 2
MIRT469305 RGP1 RGP1 homolog, RAB6A GEF complex partner 1 2 2
MIRT469771 RAB15 RAB15, member RAS oncogene family 2 2
MIRT469934 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT470000 PTPLB 3-hydroxyacyl-CoA dehydratase 2 1 1
MIRT470585 POTEM POTE ankyrin domain family member M 2 2
MIRT470615 POTEG POTE ankyrin domain family member G 2 2
MIRT470932 PKM pyruvate kinase, muscle 2 2
MIRT472511 NACC1 nucleus accumbens associated 1 2 2
MIRT472843 MTHFR methylenetetrahydrofolate reductase 2 2
MIRT473298 MEX3A mex-3 RNA binding family member A 2 2
MIRT473951 LRRC58 leucine rich repeat containing 58 2 2
MIRT474336 KMT2D lysine methyltransferase 2D 2 2
MIRT474399 KLHL28 kelch like family member 28 2 8
MIRT476487 GATAD2A GATA zinc finger domain containing 2A 2 2
MIRT477597 EFNA3 ephrin A3 2 2
MIRT477857 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT479858 CCDC6 coiled-coil domain containing 6 2 2
MIRT480123 CALR calreticulin 2 2
MIRT480391 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT480685 BRPF1 bromodomain and PHD finger containing 1 2 2
MIRT482326 AGO2 argonaute 2, RISC catalytic component 2 2
MIRT482513 ACTB actin beta 2 2
MIRT483244 CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 2 4
MIRT483282 SLC35C2 solute carrier family 35 member C2 2 4
MIRT483381 SPATA6 spermatogenesis associated 6 2 4
MIRT483416 RHOXF2B Rhox homeobox family member 2B 2 2
MIRT483468 STMN3 stathmin 3 2 4
MIRT484178 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT484460 DDX6 DEAD-box helicase 6 2 2
MIRT484515 POLD3 DNA polymerase delta 3, accessory subunit 2 2
MIRT484595 SIX3 SIX homeobox 3 2 6
MIRT484738 ABCC6 ATP binding cassette subfamily C member 6 2 4
MIRT485248 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT485592 FOSL1 FOS like 1, AP-1 transcription factor subunit 2 4
MIRT485912 PGPEP1 pyroglutamyl-peptidase I 2 4
MIRT485954 RTBDN retbindin 2 2
MIRT486597 METTL6 methyltransferase like 6 2 2
MIRT486807 NDOR1 NADPH dependent diflavin oxidoreductase 1 2 2
MIRT486972 STEAP3 STEAP3 metalloreductase 2 4
MIRT487364 C10orf54 V-set immunoregulatory receptor 2 2
MIRT488072 DLGAP3 DLG associated protein 3 2 4
MIRT488150 PRRC2B proline rich coiled-coil 2B 2 4
MIRT488454 B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 2 2
MIRT489027 PRPF4B pre-mRNA processing factor 4B 2 2
MIRT489704 CALML3 calmodulin like 3 2 2
MIRT489757 GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 2 2
MIRT490015 PIEZO1 piezo type mechanosensitive ion channel component 1 2 2
MIRT490120 FN3K fructosamine 3 kinase 2 2
MIRT490187 PKNOX2 PBX/knotted 1 homeobox 2 2 2
MIRT490313 ANK1 ankyrin 1 2 4
MIRT490595 SLC47A1 solute carrier family 47 member 1 2 4
MIRT491133 GRWD1 glutamate rich WD repeat containing 1 2 2
MIRT493027 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT494199 CLIP2 CAP-Gly domain containing linker protein 2 2 2
MIRT495699 PADI1 peptidyl arginine deiminase 1 2 2
MIRT501149 SLC10A7 solute carrier family 10 member 7 2 6
MIRT501413 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT501638 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT512047 DIRAS2 DIRAS family GTPase 2 2 4
MIRT519877 ZFP30 ZFP30 zinc finger protein 2 4
MIRT522598 MAP7D1 MAP7 domain containing 1 2 4
MIRT524787 BAG5 BCL2 associated athanogene 5 2 2
MIRT539158 AR androgen receptor 2 2
MIRT555901 ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 2 2
MIRT562543 CCDC71L coiled-coil domain containing 71 like 2 4
MIRT568791 VPS37D VPS37D, ESCRT-I subunit 2 2
MIRT569568 PRELP proline and arginine rich end leucine rich repeat protein 2 2
MIRT570000 COL1A2 collagen type I alpha 2 chain 2 2
MIRT570183 RAP1GAP2 RAP1 GTPase activating protein 2 2 2
MIRT572990 RPP25 ribonuclease P and MRP subunit p25 2 2
MIRT574618 LPCAT3 lysophosphatidylcholine acyltransferase 3 2 2
MIRT615354 CCNF cyclin F 2 2
MIRT616091 HOXB5 homeobox B5 2 2
MIRT617658 RSRC1 arginine and serine rich coiled-coil 1 2 2
MIRT619107 CD40LG CD40 ligand 2 2
MIRT621198 ARPC1B actin related protein 2/3 complex subunit 1B 2 2
MIRT628839 FAM151B family with sequence similarity 151 member B 2 2
MIRT635552 LEPREL1 prolyl 3-hydroxylase 2 2 2
MIRT635703 NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2 2
MIRT646646 FNBP1 formin binding protein 1 2 2
MIRT654905 POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2 2
MIRT655121 PHF7 PHD finger protein 7 2 2
MIRT659457 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 4
MIRT668952 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT684242 TBXA2R thromboxane A2 receptor 2 2
MIRT692701 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT694328 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT712137 TAOK1 TAO kinase 1 2 2
MIRT713672 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT715741 HSD11B1L hydroxysteroid 11-beta dehydrogenase 1 like 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4665 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4665 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-mir-4665 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4665 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4665-5p Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4665-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4665-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4665-5p Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-4665-5p Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4665-5p Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4665-5p Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-4665-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-4665-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4665-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-4665-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-4665-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4665-5p Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4665-5p Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-4665-5p Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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