miRTarBase - #MIRT193027


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pre-miRNA Information
pre-miRNA hsa-mir-518a-1   
Genomic Coordinates chr19: 53731006 - 53731090
Synonyms MIRN518A-1, MIRN518A1, MIR518A1
Description Homo sapiens miR-518a-1 stem-loop
Comment The 5' mature product was previously named miR-527 in has a 1 nt 3' extension (A), which is incompatible with the genome sequence.
RNA Secondary Structure
Associated Diseases
pre-miRNA hsa-mir-518a-2   
Genomic Coordinates chr19: 53739333 - 53739419
Synonyms MIRN518A-2, MIRN518A2, MIR518A2
Description Homo sapiens miR-518a-2 stem-loop
Comment The 5' mature product was previously named miR-527 in has a 1 nt 3' extension (A), which is incompatible with the genome sequence.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-518a-5p
Sequence 14| CUGCAAAGGGAAGCCCUUUC |33
Evidence Experimental
Experiments Array-cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs779337342 1 dbSNP
rs1220923096 2 dbSNP
rs748541083 3 dbSNP
rs1419564974 4 dbSNP
rs954777846 6 dbSNP
rs749384027 7 dbSNP
rs1466927206 9 dbSNP
rs1331417194 10 dbSNP
rs919574209 10 dbSNP
rs374228640 11 dbSNP
rs1442070388 13 dbSNP
rs759533489 16 dbSNP
rs1315177101 19 dbSNP
rs765231725 20 dbSNP
rs373104095 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TMOD3   
Synonyms UTMOD
Description tropomodulin 3
Transcript NM_014547   
Expression
Putative miRNA Targets on TMOD3
3'UTR of TMOD3
(miRNA target sites are highlighted)		 
>TMOD3|NM_014547|3'UTR
   1 GTCTGCAAAGGTGTAATCTTTGGAAGACTTCAGAAGATCACCAAGGGCTCATGTTGGTGACATCATGTAAAATTTTCCTG
  81 GGTAGAAGGGAAAAGACTGGAAAAATTTTTTTAGTGACATGCATTTTTTTTTTAGTTGTTATCAAATTGTAAAATCAGTA
 161 ATGTGATATTTTATATTCTGAAACATTTCTACTTTCTGCTAAAATCAATTTTAATTTAGTTTAATTGAATGATTTATGAT
 241 GAATCTTGGGCAAAAAAATACAACTGTAAAAAATTTCACAGGTCATTTGTGTAGAATAATTTGAACATTGTGAGGACCAA
 321 TCTTTTTTAAATCAAAAGGGATGTTGCTGGTATCAGAATTGTTATTGCTTCATTTAGACATAAAACACTTAAGTGTTTTC
 401 TTCACTCCGTGACCTGGAGAGTTTTCCATTTTTTAAAATACATGAACTTGGCAAGGGTGTGATTTTTCTTTATCAAGAGA
 481 ACAAAATGCCAGAATGTTAAAACAGTTAACTCAAAATCTAGTCATCTGTGTAGGAGCTAAAGCAGGTCTCCAGGGAGAGA
 561 GGGTGGTCGTCTGTGCATTCCAGGTTACTGCACTTGTCTGATGTGACGTAGCAACACCCAGGTCTTCTTAAAACAAAGTC
 641 ATCAGCTTTGCCAGGTTACATACTTTATTTAAAAGTATAGTGAGGTCGAAGTTCATTCCAGTGTTTCATTTTAATAATGT
 721 GGGCATTATTAAATTTTTGTGGAAGCTAATAGTAAAAAATAAAAGCTGTTTTCACCACCTCCCTCCCCACCCCCCAAAAA
 801 AGGCGTACAGCCAACTCTTAGTTATTTAGGGTAAGAGAAAAAAGAAAACTGTTAAACAATGAAATCAAAGATAATAAATA
 881 TGATAGATTTCCAGTATGAGGCACTTGCAAAACAGTCATTTAAACTGATGGTTACTGTAAGTCAGTTGGAAGCTGGCATG
 961 TATGTAAATTACTTGGTGTTACACCATATCCGAAGAAGTTCCTATGTGCAGTGCAGAATTGCATAAACAGTATTTAATCA
1041 CTGCTACAAATCTTCCAACCAAGAAGGAAAACTGCTATTCTTCATAAATCTAATTTTTAGTATATGCTTCCTTTCATCTT
1121 ATACTTTTATCAATATTTATAAAAGTCATTTCTATAATAAAAGCAGTCTTTCTTGCTCAAAGTATTAAGGTGAACAATTG
1201 AATAGAGTACTGTGGTCGGGAGACTGATTTGAGACTGCAGAGCTGATGCTGGGTAGAGGGTCTGGACTTGTATTCATGTT
1281 CTGTCTCAGGGCAGCCCCTGGAGCAGGAGATGGCAGAGGCATTTACAGCTGCAGAAAACAGGGAGGAATGGAATCTGAGG
1361 TAGCCCTGGCCTCAAAATTCAGGCCTGGCTGTATCATTTACAGAGATTTTTCTGGAGGGAAAAGTCTCATTTCTGAGGAA
1441 GGCAAGGTGGCTAATCATTATTAATTTTTTTTAAACTTTTTGGGCCGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACT
1521 TTTGGGAAGCCAAAGTGGGTGGATCACTTAAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCT
1601 ACTAAAAATCAAAAAAGTAGCCGGGTGTGGTGGTGCACACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATT
1681 GCTTGAACCTGGGAGATGGAGATTGCAGTGAGCTGAGATCGTACCACTGCACTGCAGTCTGGGTGACAAAGCAAGACTCT
1761 GTCTCAAAAAACAAACAAACAAACAAACTTTTTGAAATTGAATTGCAATATGTCTGCTACTTTGGCTTGGGCTGGACAGT
1841 TTATCTAATAAGCAAGGCAGCTTCTTGTGTGCTATGGTAATAAGCCTTCTTAACAGGCTAAGCTTCCCTCATAAGAACTG
1921 TGGTGTTTCTCTTTTTTTTTTTTTGTTTTGGTTTGTTTTGGTTTTTTGGTTTTGTTTTGTTTTGTTTTTTAAATCAGTAT
2001 CCAATGTTTTATAGGGGCCAAAGGTTAACTTTGCACTATTCCCTGTCAGTTAAAGGCCACTGATATTTTTCTAAGTTAGC
2081 AAGGCTCACTTGCTTGCTTTCTTGCCTCCCTTGCCTCCATCCCTCTCCCTTCCTACCTTCTCTATTTACCTATTTCTCTC
2161 CCTCCCTCTCTTCTCCTCTCTTTTTTTTTCCCCGCATATGCAGCTTTTTGATTGTACTTGATTTTATAGAGACTGCACAG
2241 TTCCAGCAAGATTGGGAGTCAGGCATGGAGCAGGCATCTCAGGCTACCAGAAAGAATTGGTCACCTAGACTTTCAGTCAG
2321 GCATCCTCGTTTGCATTGTCCTGTAAGTCAATTAGTTGATAAATAGTTCCCCCTTCATCCCTTAAGTTTTGTTTTTGTTT
2401 TTGTTTTTAATATAGGTAAGTGGGACTCTACCTAAAATTTTGCATCATACTTATGGGTAATATCTTTTTCATATATTATT
2481 TATCAAAGTATGAAGTTGAGTATTTTGCTTGTACCATTTCAATTCTGCATTATAGTAGTTCATTGTATAACTGAAAGAAA
2561 TGATTTCTTCATAAGTGACATTAAATATGAACATTCATCCAATTGAATTTACAAAATCTTTCCAAAATTATAAGGGAGAA
2641 AAATCGGGTTTACTTCAATCTTTAAAAATCTGGCACCTCTTAGTAACTTTCAGTATTTCTAAATTGCTCTAAAATTTTAT
2721 AATAAATAGATTAGGGTTTTGCAATAGTCTTAATTTTTAAGCCAAAGGTTTTCTGAGACCTTAGGTTTTGTAGTCTAACC
2801 AGCTTATGTGGTTATTTAAAAGAATATTCTTTGTGTTTTTAAATTGCTATTTTTAAAAAAGCTTTTTATTACCCATTTTA
2881 TAAAATGTTATACTCATATTTGTCTGAATTTTTCCAGTATTCCTACATGAAATTGTATGTATTAAAAACTCAATATTAGT
2961 GGCAAATATTAATACTATTAAAATGGATTTTGGTGCTATATTCTTGTAGCTAAAGCCTAGTAGAATTCTCAAGAATAGGT
3041 GAAATACACTTTCAAAGTTGCCTGTCATTTAAAAGACCAAATAAGCATTTTGTATTAAATAAATTAGCAGATGGTTAGAG
3121 ACTTCAAGGAGAGTTAGCTTGGTCATTTAATTGCGACTTCATGTTATTTGATTGAAATAACCCACATCCTTGCTTTGTAT
3201 AAGATATTCGCTCTGGAGAAGTTACATGTAAATAGAATTCTATAAATTGTTTTCCAGTTGACCGAGTATCTGTTGTGTTT
3281 TTGTTTAAAAAGAGGATTCCATGACATAATAAAAATTATTTTAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuUUCCCGAAGGGAAACGUc 5'
            ||||  ||  ||||||| 
Target 5' caAAGG--TTAACTTTGCAc 3'
 2019 - 2036 154.00 -10.20
2 
miRNA  3' cuUUCCCGAAG-GGAAACGuc 5'
            || | | ||  ||||||  
Target 5' acAAAGTCATCAGCTTTGCca 3'
 633 - 653 130.00 -9.90
3 
miRNA  3' cuuucccGAAGGGAAACGUc 5'
                 | |: |||||:| 
Target 5' cccacatCCTTGCTTTGTAt 3'
 3181 - 3200 129.00 -5.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26555395 14 COSMIC
COSN5755192 17 COSMIC
COSN30114412 105 COSMIC
COSN30612102 113 COSMIC
COSN15665554 134 COSMIC
COSN18747506 134 COSMIC
COSN31543226 161 COSMIC
COSN29379773 260 COSMIC
COSN28653047 271 COSMIC
COSN19027580 279 COSMIC
COSN26643791 334 COSMIC
COSN31524217 335 COSMIC
COSN31589331 339 COSMIC
COSN31565185 386 COSMIC
COSN8746432 512 COSMIC
COSN22637367 609 COSMIC
COSN31537653 688 COSMIC
COSN31527754 695 COSMIC
COSN17075954 757 COSMIC
COSN28201450 918 COSMIC
COSN16587752 928 COSMIC
COSN21756836 1033 COSMIC
COSN1177772 1306 COSMIC
COSN22973436 1503 COSMIC
COSN8174492 2218 COSMIC
COSN32072419 2232 COSMIC
COSN17702700 2274 COSMIC
COSN8746433 2576 COSMIC
COSN9626158 2825 COSMIC
COSN1678859 3095 COSMIC
COSN21315563 3476 COSMIC
COSN23806870 3631 COSMIC
COSN23854949 4238 COSMIC
COSN1678860 4726 COSMIC
COSN1678861 4885 COSMIC
COSN6275324 5749 COSMIC
COSN22410601 5962 COSMIC
COSN20793807 6008 COSMIC
COSN25487937 6058 COSMIC
COSN26691067 6081 COSMIC
COSN26809264 6312 COSMIC
COSN15704724 6558 COSMIC
COSN24019099 6813 COSMIC
rs2570218 625 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1218330378 1 dbSNP
rs976032846 5 dbSNP
rs1168312694 6 dbSNP
rs1474841531 7 dbSNP
rs1186184705 8 dbSNP
rs1396353628 11 dbSNP
rs1454685944 12 dbSNP
rs770343233 13 dbSNP
rs529994559 14 dbSNP
rs749732321 16 dbSNP
rs374970124 18 dbSNP
rs773859023 19 dbSNP
rs1434618803 22 dbSNP
rs1233463757 23 dbSNP
rs547912315 24 dbSNP
rs200837938 28 dbSNP
rs759290865 32 dbSNP
rs763018645 40 dbSNP
rs1235741336 47 dbSNP
rs779060752 48 dbSNP
rs1264789335 57 dbSNP
rs372092293 58 dbSNP
rs1248196609 61 dbSNP
rs888235768 63 dbSNP
rs569625038 66 dbSNP
rs1348572245 67 dbSNP
rs1282375489 68 dbSNP
rs911047284 98 dbSNP
rs1034216465 99 dbSNP
rs960163093 105 dbSNP
rs1279587681 106 dbSNP
rs1240787475 116 dbSNP
rs1333594551 119 dbSNP
rs1307863790 120 dbSNP
rs941218606 121 dbSNP
rs1038103361 124 dbSNP
rs1311597031 124 dbSNP
rs375099937 124 dbSNP
rs1408845047 125 dbSNP
rs1160341659 134 dbSNP
rs1468840575 135 dbSNP
rs1199550422 136 dbSNP
rs1253579411 139 dbSNP
rs1411488330 143 dbSNP
rs536794146 146 dbSNP
rs929723443 150 dbSNP
rs1020219928 162 dbSNP
rs1422281431 169 dbSNP
rs113829162 174 dbSNP
rs1169091888 175 dbSNP
rs1284394131 176 dbSNP
rs111519940 188 dbSNP
rs1224948037 192 dbSNP
rs1348173191 196 dbSNP
rs1287320660 204 dbSNP
rs1233447984 208 dbSNP
rs1431907448 210 dbSNP
rs1466829278 237 dbSNP
rs1302613325 239 dbSNP
rs1400386734 241 dbSNP
rs1346283329 244 dbSNP
rs191233210 246 dbSNP
rs1399016238 255 dbSNP
rs1387912154 260 dbSNP
rs772037410 261 dbSNP
rs78822477 271 dbSNP
rs893293137 280 dbSNP
rs1216731569 281 dbSNP
rs1285067417 286 dbSNP
rs985959896 290 dbSNP
rs1312574607 294 dbSNP
rs1472457381 308 dbSNP
rs753664628 321 dbSNP
rs1369047703 332 dbSNP
rs911373781 340 dbSNP
rs1020471101 341 dbSNP
rs967409656 356 dbSNP
rs1486680092 366 dbSNP
rs997566954 372 dbSNP
rs1216866505 373 dbSNP
rs1228093417 383 dbSNP
rs1261851974 401 dbSNP
rs944208502 402 dbSNP
rs1030284884 408 dbSNP
rs1486983743 409 dbSNP
rs976998145 410 dbSNP
rs985380668 411 dbSNP
rs1463251167 427 dbSNP
rs564039849 429 dbSNP
rs553924614 436 dbSNP
rs1404547235 442 dbSNP
rs1419883886 449 dbSNP
rs1188222508 452 dbSNP
rs1246923889 453 dbSNP
rs1434230458 453 dbSNP
rs528105936 457 dbSNP
rs536535706 458 dbSNP
rs888184346 460 dbSNP
rs1376273941 463 dbSNP
rs116176374 466 dbSNP
rs1263308488 488 dbSNP
rs1220282512 490 dbSNP
rs1159410294 499 dbSNP
rs918431265 500 dbSNP
rs1275492384 510 dbSNP
rs576336839 511 dbSNP
rs543563966 512 dbSNP
rs1360021635 514 dbSNP
rs929672387 517 dbSNP
rs76011352 519 dbSNP
rs1014537607 529 dbSNP
rs937033249 555 dbSNP
rs1443129436 561 dbSNP
rs1056033490 562 dbSNP
rs1172216924 564 dbSNP
rs1427794080 567 dbSNP
rs1020209897 568 dbSNP
rs1389464555 569 dbSNP
rs1368262995 570 dbSNP
rs893356435 571 dbSNP
rs1264580793 576 dbSNP
rs1386134921 578 dbSNP
rs1480730190 584 dbSNP
rs768290910 597 dbSNP
rs1298996793 604 dbSNP
rs776020707 608 dbSNP
rs903366307 609 dbSNP
rs997547190 623 dbSNP
rs2570218 625 dbSNP
rs958300756 630 dbSNP
rs1310530921 640 dbSNP
rs1300619901 655 dbSNP
rs1224574845 665 dbSNP
rs1375770774 666 dbSNP
rs769186922 667 dbSNP
rs1299725136 676 dbSNP
rs1369644023 687 dbSNP
rs1313419414 688 dbSNP
rs774878599 689 dbSNP
rs1375456363 696 dbSNP
rs541257883 702 dbSNP
rs559572981 703 dbSNP
rs1174705425 705 dbSNP
rs1419358620 716 dbSNP
rs1409694240 721 dbSNP
rs373284880 734 dbSNP
rs375716526 747 dbSNP
rs1482938394 750 dbSNP
rs182692247 762 dbSNP
rs1007948180 766 dbSNP
rs1482541163 770 dbSNP
rs1255528653 774 dbSNP
rs1216573062 777 dbSNP
rs1319022101 778 dbSNP
rs1489127544 786 dbSNP
rs1191069152 792 dbSNP
rs760015903 795 dbSNP
rs34585978 796 dbSNP
rs974019328 796 dbSNP
rs542105188 799 dbSNP
rs1301816964 800 dbSNP
rs951227747 805 dbSNP
rs981175986 806 dbSNP
rs566376791 809 dbSNP
rs1419073607 811 dbSNP
rs1379966047 813 dbSNP
rs186836634 816 dbSNP
rs1256060487 817 dbSNP
rs1398028279 818 dbSNP
rs937126884 818 dbSNP
rs1266259491 823 dbSNP
rs1418060299 842 dbSNP
rs984350613 844 dbSNP
rs991535745 845 dbSNP
rs1350527270 858 dbSNP
rs1273632414 860 dbSNP
rs1246704888 869 dbSNP
rs1457356284 881 dbSNP
rs909512985 889 dbSNP
rs1338701765 890 dbSNP
rs140548619 901 dbSNP
rs1382659216 909 dbSNP
rs1375296087 914 dbSNP
rs1447309221 918 dbSNP
rs1055540947 920 dbSNP
rs947590675 941 dbSNP
rs895593384 946 dbSNP
rs903346406 950 dbSNP
rs552007572 954 dbSNP
rs879655087 955 dbSNP
rs1041599663 958 dbSNP
rs903028479 960 dbSNP
rs1000087447 963 dbSNP
rs1246302342 972 dbSNP
rs1289991437 979 dbSNP
rs889169990 983 dbSNP
rs570241596 992 dbSNP
rs893775576 993 dbSNP
rs1459462672 997 dbSNP
rs1007338367 1005 dbSNP
rs1199702734 1017 dbSNP
rs899204130 1020 dbSNP
rs1438126764 1023 dbSNP
rs150466758 1028 dbSNP
rs1325130930 1029 dbSNP
rs1025595925 1030 dbSNP
rs1390500478 1047 dbSNP
rs1168818115 1048 dbSNP
rs1432222218 1053 dbSNP
rs1388839411 1055 dbSNP
rs951176923 1058 dbSNP
rs1414632026 1078 dbSNP
rs1423278383 1085 dbSNP
rs548481782 1101 dbSNP
rs1402423947 1106 dbSNP
rs867684859 1109 dbSNP
rs1196138733 1118 dbSNP
rs1466073092 1122 dbSNP
rs976876235 1123 dbSNP
rs369105040 1128 dbSNP
rs1397779313 1130 dbSNP
rs1025739248 1133 dbSNP
rs1284385130 1134 dbSNP
rs1348002456 1140 dbSNP
rs1377844210 1145 dbSNP
rs1230653779 1148 dbSNP
rs1330122850 1153 dbSNP
rs1330035677 1164 dbSNP
rs1412056430 1172 dbSNP
rs11537938 1179 dbSNP
rs868317956 1186 dbSNP
rs547622383 1193 dbSNP
rs760819706 1197 dbSNP
rs565929698 1199 dbSNP
rs536546359 1203 dbSNP
rs968439726 1208 dbSNP
rs773618711 1218 dbSNP
rs924840396 1219 dbSNP
rs910158532 1226 dbSNP
rs958395109 1234 dbSNP
rs1473457350 1238 dbSNP
rs1249285154 1239 dbSNP
rs933586529 1250 dbSNP
rs991585081 1252 dbSNP
rs916991124 1254 dbSNP
rs1198214550 1256 dbSNP
rs1343933945 1256 dbSNP
rs1279778169 1260 dbSNP
rs1229792344 1264 dbSNP
rs867170672 1277 dbSNP
rs1349045347 1282 dbSNP
rs1456667960 1286 dbSNP
rs1212548374 1287 dbSNP
rs949808504 1289 dbSNP
rs1483031076 1296 dbSNP
rs74408321 1301 dbSNP
rs1425859391 1305 dbSNP
rs1385684297 1317 dbSNP
rs569968004 1333 dbSNP
rs1161676282 1340 dbSNP
rs537425966 1344 dbSNP
rs1455804452 1363 dbSNP
rs1181156840 1364 dbSNP
rs1478115935 1364 dbSNP
rs899148877 1365 dbSNP
rs751094441 1367 dbSNP
rs754002817 1370 dbSNP
rs1169793881 1372 dbSNP
rs1421254312 1387 dbSNP
rs1415916089 1406 dbSNP
rs935830750 1416 dbSNP
rs1054367962 1450 dbSNP
rs757394817 1452 dbSNP
rs1284294172 1458 dbSNP
rs1358255335 1465 dbSNP
rs1006875043 1469 dbSNP
rs558973934 1473 dbSNP
rs1445346155 1474 dbSNP
rs1040139094 1484 dbSNP
rs1203821719 1487 dbSNP
rs1002800557 1488 dbSNP
rs1282954927 1490 dbSNP
rs901186686 1491 dbSNP
rs1261428385 1492 dbSNP
rs958607301 1496 dbSNP
rs1013065377 1503 dbSNP
rs998202015 1504 dbSNP
rs779110077 1510 dbSNP
rs750405632 1515 dbSNP
rs968889790 1521 dbSNP
rs866257543 1522 dbSNP
rs1472403503 1532 dbSNP
rs1278077030 1534 dbSNP
rs1189918598 1536 dbSNP
rs1463315733 1543 dbSNP
rs924287196 1544 dbSNP
rs758369367 1555 dbSNP
rs954919152 1557 dbSNP
rs138204329 1558 dbSNP
rs1017167140 1567 dbSNP
rs1228290629 1569 dbSNP
rs1279778846 1592 dbSNP
rs1340644858 1598 dbSNP
rs943579027 1602 dbSNP
rs1432984491 1604 dbSNP
rs1364462646 1611 dbSNP
rs756868700 1623 dbSNP
rs1351437084 1624 dbSNP
rs1438818573 1624 dbSNP
rs541528591 1626 dbSNP
rs1390702134 1628 dbSNP
rs1265435717 1637 dbSNP
rs1170017511 1651 dbSNP
rs1447136940 1653 dbSNP
rs780867514 1654 dbSNP
rs1191440694 1659 dbSNP
rs2554347 1660 dbSNP
rs929390991 1666 dbSNP
rs1277401776 1675 dbSNP
rs192132706 1680 dbSNP
rs1478953368 1689 dbSNP
rs1173009243 1704 dbSNP
rs1304207365 1709 dbSNP
rs1221195514 1721 dbSNP
rs780969081 1722 dbSNP
rs541772939 1733 dbSNP
rs1424186679 1743 dbSNP
rs747724969 1744 dbSNP
rs28564415 1752 dbSNP
rs1160010159 1753 dbSNP
rs1435496772 1766 dbSNP
rs1370869371 1769 dbSNP
rs1427693923 1769 dbSNP
rs372455102 1769 dbSNP
rs1369440696 1777 dbSNP
rs3210633 1778 dbSNP
rs1360641770 1781 dbSNP
rs3210634 1786 dbSNP
rs747048112 1786 dbSNP
rs769343421 1793 dbSNP
rs1422615697 1799 dbSNP
rs1190206131 1800 dbSNP
rs34280122 1801 dbSNP
rs558642855 1801 dbSNP
rs563569478 1809 dbSNP
rs1054721486 1820 dbSNP
rs530693110 1826 dbSNP
rs1256716527 1829 dbSNP
rs146596897 1830 dbSNP
rs1310736131 1837 dbSNP
rs576787399 1839 dbSNP
rs1300856382 1840 dbSNP
rs1229185639 1842 dbSNP
rs1350914253 1845 dbSNP
rs1012726867 1849 dbSNP
rs1407968194 1853 dbSNP
rs1367264081 1857 dbSNP
rs1302989896 1861 dbSNP
rs1467135437 1867 dbSNP
rs1040310417 1868 dbSNP
rs1174940105 1869 dbSNP
rs904245212 1870 dbSNP
rs998563618 1875 dbSNP
rs563726162 1876 dbSNP
rs1472584340 1878 dbSNP
rs1257482875 1887 dbSNP
rs901129897 1892 dbSNP
rs1255441686 1894 dbSNP
rs1031294128 1896 dbSNP
rs1331451721 1904 dbSNP
rs954412060 1909 dbSNP
rs987669386 1914 dbSNP
rs998174393 1916 dbSNP
rs534699295 1920 dbSNP
rs1047132203 1923 dbSNP
rs1316047432 1928 dbSNP
rs11446467 1932 dbSNP
rs1301720682 1932 dbSNP
rs1390368668 1932 dbSNP
rs398057685 1932 dbSNP
rs761815911 1932 dbSNP
rs878899904 1932 dbSNP
rs1017879329 1934 dbSNP
rs1457051922 1938 dbSNP
rs887214691 1940 dbSNP
rs528215214 1941 dbSNP
rs973569161 1941 dbSNP
rs920770536 1942 dbSNP
rs79581647 1943 dbSNP
rs983575654 1943 dbSNP
rs1246427167 1944 dbSNP
rs1216041155 1945 dbSNP
rs866703407 1946 dbSNP
rs927945005 1947 dbSNP
rs1246956089 1950 dbSNP
rs1199411081 1951 dbSNP
rs1313813428 1952 dbSNP
rs931669469 1956 dbSNP
rs1366663282 1960 dbSNP
rs1476894360 1960 dbSNP
rs1180147504 1961 dbSNP
rs1380580465 1962 dbSNP
rs939354411 1965 dbSNP
rs1156367579 1969 dbSNP
rs1169704350 1969 dbSNP
rs1456889573 1969 dbSNP
rs1451424667 1970 dbSNP
rs1135871 1974 dbSNP
rs2470609 1979 dbSNP
rs894361595 1980 dbSNP
rs948650759 1984 dbSNP
rs1487503561 1985 dbSNP
rs1290953656 1986 dbSNP
rs1013543855 2005 dbSNP
rs1343711652 2006 dbSNP
rs531802794 2011 dbSNP
rs971045559 2015 dbSNP
rs1331309286 2022 dbSNP
rs1311883544 2037 dbSNP
rs1385455523 2040 dbSNP
rs1365277468 2043 dbSNP
rs1309194329 2046 dbSNP
rs1432125509 2048 dbSNP
rs1378017732 2050 dbSNP
rs1368834793 2057 dbSNP
rs977126361 2060 dbSNP
rs568435341 2066 dbSNP
rs1167387577 2067 dbSNP
rs1239673598 2071 dbSNP
rs1307190604 2074 dbSNP
rs1031409243 2086 dbSNP
rs904403705 2088 dbSNP
rs796234849 2097 dbSNP
rs1210388367 2098 dbSNP
rs1288995901 2102 dbSNP
rs998553792 2102 dbSNP
rs1271928417 2112 dbSNP
rs957138167 2115 dbSNP
rs1345015636 2116 dbSNP
rs138998988 2120 dbSNP
rs1230551269 2124 dbSNP
rs1345310915 2134 dbSNP
rs537331317 2136 dbSNP
rs1289341203 2137 dbSNP
rs574380273 2141 dbSNP
rs890107467 2144 dbSNP
rs910353236 2145 dbSNP
rs1415115647 2149 dbSNP
rs1238547675 2156 dbSNP
rs1438710633 2157 dbSNP
rs552644136 2162 dbSNP
rs1469451533 2166 dbSNP
rs1428391527 2168 dbSNP
rs761167373 2170 dbSNP
rs1473569000 2173 dbSNP
rs143012506 2175 dbSNP
rs974069314 2176 dbSNP
rs776957135 2178 dbSNP
rs1257609630 2181 dbSNP
rs1322371453 2181 dbSNP
rs933973012 2181 dbSNP
rs1269226857 2186 dbSNP
rs1390699765 2189 dbSNP
rs563314264 2190 dbSNP
rs75379544 2190 dbSNP
rs11446468 2191 dbSNP
rs887120356 2194 dbSNP
rs1333853332 2195 dbSNP
rs535127291 2197 dbSNP
rs1332241230 2199 dbSNP
rs1452256319 2203 dbSNP
rs1389648810 2209 dbSNP
rs941423963 2211 dbSNP
rs1458626069 2213 dbSNP
rs1405455369 2214 dbSNP
rs144577332 2215 dbSNP
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rs937933872 5529 dbSNP
rs1232838666 5536 dbSNP
rs549557505 5539 dbSNP
rs1353793801 5544 dbSNP
rs1310887751 5547 dbSNP
rs1445182213 5555 dbSNP
rs1376854927 5561 dbSNP
rs1053517148 5565 dbSNP
rs1249838338 5576 dbSNP
rs915111032 5577 dbSNP
rs151082294 5578 dbSNP
rs1049613638 5591 dbSNP
rs1418340940 5593 dbSNP
rs538745122 5598 dbSNP
rs553866544 5599 dbSNP
rs2593178 5605 dbSNP
rs534155052 5622 dbSNP
rs142553582 5629 dbSNP
rs896766656 5630 dbSNP
rs1484114591 5637 dbSNP
rs1235589663 5641 dbSNP
rs1390189553 5644 dbSNP
rs185700361 5647 dbSNP
rs544888888 5648 dbSNP
rs1237354930 5649 dbSNP
rs1316786681 5651 dbSNP
rs1230604206 5652 dbSNP
rs1314072644 5652 dbSNP
rs562548790 5653 dbSNP
rs1271641399 5655 dbSNP
rs1284029152 5665 dbSNP
rs1000582595 5669 dbSNP
rs2593177 5675 dbSNP
rs953875995 5676 dbSNP
rs1296361550 5682 dbSNP
rs1008037627 5688 dbSNP
rs1419183129 5693 dbSNP
rs1344462943 5697 dbSNP
rs1250865303 5700 dbSNP
rs1019477465 5706 dbSNP
rs1425545369 5708 dbSNP
rs1479672605 5716 dbSNP
rs545116021 5717 dbSNP
rs1190129326 5721 dbSNP
rs961248541 5725 dbSNP
rs1477916800 5726 dbSNP
rs377545509 5727 dbSNP
rs1213741613 5728 dbSNP
rs1485259164 5742 dbSNP
rs1265580597 5748 dbSNP
rs1224402722 5749 dbSNP
rs1320486448 5753 dbSNP
rs35677490 5753 dbSNP
rs753510950 5757 dbSNP
rs1474838538 5762 dbSNP
rs1293017606 5771 dbSNP
rs1219655042 5774 dbSNP
rs994252437 5782 dbSNP
rs560187013 5784 dbSNP
rs2433222 5785 dbSNP
rs1410212494 5791 dbSNP
rs952150465 5796 dbSNP
rs984886565 5802 dbSNP
rs1034321116 5805 dbSNP
rs1163871850 5809 dbSNP
rs926734346 5810 dbSNP
rs1425593717 5837 dbSNP
rs959275666 5837 dbSNP
rs989397053 5849 dbSNP
rs1427611459 5851 dbSNP
rs1267403003 5853 dbSNP
rs548945224 5856 dbSNP
rs1487761738 5861 dbSNP
rs1273120413 5862 dbSNP
rs938142305 5865 dbSNP
rs1320438286 5873 dbSNP
rs561131580 5879 dbSNP
rs992358480 5884 dbSNP
rs1313038623 5885 dbSNP
rs918105500 5888 dbSNP
rs945627601 5903 dbSNP
rs1352378198 5907 dbSNP
rs542540348 5913 dbSNP
rs933757180 5916 dbSNP
rs1325133817 5919 dbSNP
rs1447498848 5920 dbSNP
rs879340928 5927 dbSNP
rs889487658 5927 dbSNP
rs903509011 5927 dbSNP
rs1312948464 5931 dbSNP
rs1377862801 5943 dbSNP
rs778488356 5946 dbSNP
rs1049447592 5952 dbSNP
rs889558068 5961 dbSNP
rs1007944672 5962 dbSNP
rs865982141 5965 dbSNP
rs1019382883 5967 dbSNP
rs897425890 5968 dbSNP
rs12903448 5969 dbSNP
rs1364478943 5972 dbSNP
rs531507538 5975 dbSNP
rs994063626 5976 dbSNP
rs1257990463 5979 dbSNP
rs550057116 5985 dbSNP
rs1213195479 5986 dbSNP
rs1347228618 5989 dbSNP
rs952077575 5994 dbSNP
rs985220832 5996 dbSNP
rs1033750561 5997 dbSNP
rs12903466 5998 dbSNP
rs1240751974 6003 dbSNP
rs369671252 6003 dbSNP
rs571278606 6003 dbSNP
rs992264977 6005 dbSNP
rs141541762 6008 dbSNP
rs995548003 6008 dbSNP
rs547394207 6011 dbSNP
rs2448949 6023 dbSNP
rs1442044165 6026 dbSNP
rs989343103 6062 dbSNP
rs1181457291 6071 dbSNP
rs374093594 6072 dbSNP
rs1022137865 6078 dbSNP
rs1485492731 6079 dbSNP
rs1286780922 6080 dbSNP
rs966670064 6081 dbSNP
rs1277705306 6083 dbSNP
rs978289845 6084 dbSNP
rs1455293327 6089 dbSNP
rs1340827893 6090 dbSNP
rs757914676 6099 dbSNP
rs536337114 6108 dbSNP
rs555731447 6109 dbSNP
rs1434679798 6111 dbSNP
rs1298220608 6112 dbSNP
rs1332721235 6113 dbSNP
rs1347446162 6114 dbSNP
rs1382230016 6117 dbSNP
rs1158483450 6119 dbSNP
rs985244811 6124 dbSNP
rs1370535646 6126 dbSNP
rs936335486 6130 dbSNP
rs1474976790 6133 dbSNP
rs113200971 6142 dbSNP
rs1218796825 6143 dbSNP
rs1038062064 6148 dbSNP
rs889468522 6152 dbSNP
rs1266948019 6153 dbSNP
rs1236703009 6156 dbSNP
rs527646755 6157 dbSNP
rs943750400 6158 dbSNP
rs930253096 6159 dbSNP
rs1046312186 6162 dbSNP
rs1317071969 6167 dbSNP
rs1040778639 6168 dbSNP
rs1393549279 6170 dbSNP
rs1163159840 6172 dbSNP
rs1347179307 6173 dbSNP
rs907407882 6176 dbSNP
rs1002007887 6179 dbSNP
rs1241561973 6183 dbSNP
rs536957628 6186 dbSNP
rs1452060768 6191 dbSNP
rs1286307761 6194 dbSNP
rs538164866 6203 dbSNP
rs896980353 6210 dbSNP
rs556408449 6211 dbSNP
rs117026942 6212 dbSNP
rs1026885863 6213 dbSNP
rs1436594023 6217 dbSNP
rs888390372 6222 dbSNP
rs1393982480 6223 dbSNP
rs545030617 6228 dbSNP
rs1324460690 6230 dbSNP
rs1440890510 6235 dbSNP
rs1029905870 6236 dbSNP
rs1173322509 6241 dbSNP
rs1033658814 6244 dbSNP
rs796751106 6246 dbSNP
rs1013643896 6253 dbSNP
rs1479050730 6254 dbSNP
rs1393411951 6261 dbSNP
rs1191646442 6264 dbSNP
rs547492421 6265 dbSNP
rs1025101435 6271 dbSNP
rs1468011483 6277 dbSNP
rs985305341 6286 dbSNP
rs966883686 6289 dbSNP
rs978692170 6290 dbSNP
rs879760721 6297 dbSNP
rs1410889158 6304 dbSNP
rs149544627 6307 dbSNP
rs1158855115 6309 dbSNP
rs1386826291 6310 dbSNP
rs958508079 6317 dbSNP
rs973702281 6325 dbSNP
rs1346485874 6337 dbSNP
rs1443406070 6339 dbSNP
rs1234158959 6344 dbSNP
rs1378330177 6345 dbSNP
rs770332396 6346 dbSNP
rs2162224 6349 dbSNP
rs910852960 6350 dbSNP
rs543058996 6354 dbSNP
rs1354087382 6359 dbSNP
rs1434487930 6360 dbSNP
rs762702043 6364 dbSNP
rs943739084 6374 dbSNP
rs375052975 6388 dbSNP
rs1040770415 6393 dbSNP
rs1393315578 6403 dbSNP
rs918356418 6407 dbSNP
rs930218224 6416 dbSNP
rs1453676615 6419 dbSNP
rs929814369 6428 dbSNP
rs1380861085 6437 dbSNP
rs1178660786 6441 dbSNP
rs1468408749 6450 dbSNP
rs1232143580 6460 dbSNP
rs1210354795 6465 dbSNP
rs1046005368 6472 dbSNP
rs1277517128 6474 dbSNP
rs1048674599 6478 dbSNP
rs1354976253 6484 dbSNP
rs2929424 6493 dbSNP
rs1373025594 6494 dbSNP
rs1281928265 6503 dbSNP
rs1450421372 6509 dbSNP
rs1055906591 6514 dbSNP
rs549900717 6521 dbSNP
rs893183878 6522 dbSNP
rs543760762 6530 dbSNP
rs895142213 6531 dbSNP
rs565205777 6533 dbSNP
rs1466855849 6537 dbSNP
rs1025043677 6538 dbSNP
rs1041690755 6543 dbSNP
rs751482598 6544 dbSNP
rs1186521357 6551 dbSNP
rs1029607516 6564 dbSNP
rs113529903 6564 dbSNP
rs1316877000 6564 dbSNP
rs1488328905 6564 dbSNP
rs967166012 6567 dbSNP
rs532430500 6569 dbSNP
rs1470802247 6571 dbSNP
rs1235549924 6573 dbSNP
rs1177084641 6582 dbSNP
rs1353727542 6583 dbSNP
rs955492776 6585 dbSNP
rs1400905846 6590 dbSNP
rs999633796 6599 dbSNP
rs1018131328 6602 dbSNP
rs1032883891 6620 dbSNP
rs962447520 6628 dbSNP
rs1463380610 6630 dbSNP
rs542118226 6631 dbSNP
rs1462821626 6641 dbSNP
rs1415483501 6649 dbSNP
rs1394092583 6650 dbSNP
rs958207190 6660 dbSNP
rs1163742183 6667 dbSNP
rs1477967005 6668 dbSNP
rs1263171825 6670 dbSNP
rs973857762 6672 dbSNP
rs569510226 6673 dbSNP
rs1247809168 6685 dbSNP
rs985667967 6686 dbSNP
rs1273007408 6691 dbSNP
rs1219441916 6708 dbSNP
rs1309514787 6710 dbSNP
rs774505065 6714 dbSNP
rs951109409 6721 dbSNP
rs1286436681 6724 dbSNP
rs964996735 6728 dbSNP
rs1326493142 6734 dbSNP
rs189315126 6742 dbSNP
rs1391975840 6754 dbSNP
rs531155345 6757 dbSNP
rs1272300878 6758 dbSNP
rs929694926 6767 dbSNP
rs1332238618 6768 dbSNP
rs1167623628 6769 dbSNP
rs1197115186 6770 dbSNP
rs1048148050 6779 dbSNP
rs937596991 6785 dbSNP
rs909674607 6787 dbSNP
rs1196030977 6788 dbSNP
rs775451372 6789 dbSNP
rs1252713890 6791 dbSNP
rs947470084 6792 dbSNP
rs1055700265 6818 dbSNP
rs760553444 6819 dbSNP
rs117715226 6825 dbSNP
rs1312832521 6836 dbSNP
rs1305782075 6838 dbSNP
rs529756537 6840 dbSNP
rs933313960 6841 dbSNP
rs1046803518 6845 dbSNP
rs866484821 6850 dbSNP
rs1471949454 6858 dbSNP
rs548228689 6866 dbSNP
rs191499520 6873 dbSNP
rs1032461255 6878 dbSNP
rs538023362 6884 dbSNP
rs893972694 6885 dbSNP
rs866810851 6889 dbSNP
rs1375491687 6899 dbSNP
rs575855669 6899 dbSNP
rs761539146 6903 dbSNP
rs1395020651 6912 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 29766.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
Experimental Support 4 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions MCF7
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRR1045082. RNA binding protein: AGO2. Condition:Untreated ...

- Farazi TA; Ten Hoeve JJ; Brown M; et al., 2014, Genome biology.

Article - Farazi TA; Ten Hoeve JJ; Brown M; et al.
- Genome biology, 2014
BACKGROUND: Various microRNAs (miRNAs) are up- or downregulated in tumors. However, the repression of cognate miRNA targets responsible for the phenotypic effects of this dysregulation in patients remains largely unexplored. To define miRNA targets and associated pathways, together with their relationship to outcome in breast cancer, we integrated patient-paired miRNA-mRNA expression data with a set of validated miRNA targets and pathway inference. RESULTS: To generate a biochemically-validated set of miRNA-binding sites, we performed argonaute-2 photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation (AGO2-PAR-CLIP) in MCF7 cells. We then defined putative miRNA-target interactions using a computational model, which ranked and selected additional TargetScan-predicted interactions based on features of our AGO2-PAR-CLIP binding-site data. We subselected modeled interactions according to the abundance of their constituent miRNA and mRNA transcripts in tumors, and we took advantage of the variability of miRNA expression within molecular subtypes to detect miRNA repression. Interestingly, our data suggest that miRNA families control subtype-specific pathways; for example, miR-17, miR-19a, miR-25, and miR-200b show high miRNA regulatory activity in the triple-negative, basal-like subtype, whereas miR-22 and miR-24 do so in the HER2 subtype. An independent dataset validated our findings for miR-17 and miR-25, and showed a correlation between the expression levels of miR-182 targets and overall patient survival. Pathway analysis associated miR-17, miR-19a, and miR-200b with leukocyte transendothelial migration. CONCLUSIONS: We combined PAR-CLIP data with patient expression data to predict regulatory miRNAs, revealing potential therapeutic targets and prognostic markers in breast cancer.
LinkOut: [PMID: 24398324]
CLIP-seq Support 1 for dataset GSM4903825
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / PID14_NS
Location of target site NM_014547 | 3UTR | AAAGGUUAACUUUGCACUAUUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161237
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_014547 | 3UTR | UUGGUUUGUUUUGGUUUUUUGGUUUUGUUUUGUUUUGUUUUUUAAAUCAGUAUCCAAUGUUUUAUAGGGGCCAAAGGUUAACUUUGCACUAUUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_014547 | 3UTR | UUUUGGUUUUUUGGUUUUGUUUUGUUUUGUUUUUUAAAUCAGUAUCCAAUGUUUUAUAGGGGCCAAAGGUUAACUUUGCACUAUUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_014547 | 3UTR | UUGUUUUGUUUUGUUUUUUAAAUCAGUAUCCAAUGUUUUAUAGGGGCCAAAGGUUAACUUUGCACUAUUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_014547 | 3UTR | UUUGUUUUGUUUUUUAAAUCAGUAUCCAAUGUUUUAUAGGGGCCAAAGGUUAACUUUGCACUAUUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_014547 | 3UTR | CCAAUGUUUUAUAGGGGCCAAAGGUUAACUUUGCACUAUUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_014547 | 3UTR | UUUUGUUUUGUUUUGUUUUUUAAAUCAGUAUCCAAUGUUUUAUAGGGGCCAAAGGUUAACUUUGCACUAUUCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM545212
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / Control
Location of target site ENST00000308580.7 | 3UTR | UUAACUUUGCACUAUUCCCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM545214
Method / RBP PAR-CLIP / AGO3
Cell line / Condition HEK293 / Control
Location of target site ENST00000308580.7 | 3UTR | UUAACUUUGCACUAUUCCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 10 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000308580.7 | 3UTR | UUAACUUUGCACUAUUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 11 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000308580.7 | 3UTR | UUAACUUUGCACUAUUCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 12 for dataset SRR1045082
Method / RBP PAR-CLIP / AGO2
Cell line / Condition MCF7 / Untreated
Location of target site ENST00000308580.7 | 3UTR | UUAACUUUGCACUAUUCCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 24398324 / SRX388831
CLIP-seq Viewer Link
CLIP-seq Support 13 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000308580.7 | 3UTR | GGCCAAAGGUUAACUUUGCACUAUUCCCUGUCAGUUAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.583 1.4e-3 0.624 5.6e-4 24 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.412 2.0e-2 0.489 6.6e-3 25 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.274 1.2e-1 0.293 1.0e-1 20 Click to see details
GSE26953 Aortic valvular endothelial cells -0.21 1.6e-1 -0.234 1.4e-1 24 Click to see details
GSE32688 Pancreatic cancer -0.153 2.0e-1 -0.144 2.2e-1 32 Click to see details
GSE14794 Lymphoblastoid cells -0.083 2.2e-1 -0.129 1.1e-1 90 Click to see details
GSE42095 Differentiated embryonic stem cells -0.119 2.9e-1 -0.127 2.8e-1 23 Click to see details
GSE38226 Liver fibrosis 0.03 4.5e-1 0.466 1.7e-2 21 Click to see details
GSE28260 Renal cortex and medulla -0.005 4.9e-1 -0.033 4.6e-1 13 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
BRCA 0.819 0.09 0.400 0.3 4 Click to see details
HNSC 0.13 0.46 -0.500 0.33 3 Click to see details
HNSC 0.13 0.46 -0.500 0.33 3 Click to see details
HNSC 0.13 0.46 -0.500 0.33 3 Click to see details
HNSC 0.13 0.46 -0.500 0.33 3 Click to see details
HNSC 0.13 0.46 -0.500 0.33 3 Click to see details
HNSC 0.13 0.46 -0.500 0.33 3 Click to see details
HNSC 0.13 0.46 -0.500 0.33 3 Click to see details
152 hsa-miR-518a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT004667 MCL1 MCL1, BCL2 family apoptosis regulator 3 1
MIRT060823 CEP350 centrosomal protein 350 2 2
MIRT072482 RAB8B RAB8B, member RAS oncogene family 2 2
MIRT076138 WDR81 WD repeat domain 81 2 2
MIRT076233 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 6
MIRT082391 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 2 4
MIRT090336 SEC61A1 Sec61 translocon alpha 1 subunit 2 8
MIRT091943 ZBTB47 zinc finger and BTB domain containing 47 2 6
MIRT092025 ABHD5 abhydrolase domain containing 5 2 6
MIRT095381 UBE2D2 ubiquitin conjugating enzyme E2 D2 2 2
MIRT142423 TNRC6A trinucleotide repeat containing 6A 2 6
MIRT149875 LDLR low density lipoprotein receptor 2 2
MIRT168656 MAPK14 mitogen-activated protein kinase 14 2 2
MIRT178931 C11ORF57 chromosome 11 open reading frame 57 2 2
MIRT179070 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 6
MIRT193027 TMOD3 tropomodulin 3 2 8
MIRT195757 ATMIN ATM interactor 2 6
MIRT210001 LIMD1 LIM domains containing 1 2 2
MIRT211285 ANKRD50 ankyrin repeat domain 50 2 2
MIRT217608 NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit 2 2
MIRT230978 PRRG4 proline rich and Gla domain 4 2 2
MIRT248250 SP1 Sp1 transcription factor 2 2
MIRT249362 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 2 2
MIRT257798 CDC5L cell division cycle 5 like 2 4
MIRT267984 UCK2 uridine-cytidine kinase 2 2 2
MIRT301220 SH3BP4 SH3 domain binding protein 4 2 2
MIRT312573 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT315532 MARCKS myristoylated alanine rich protein kinase C substrate 2 2
MIRT343048 ABHD2 abhydrolase domain containing 2 2 2
MIRT442635 TBC1D12 TBC1 domain family member 12 2 2
MIRT443425 MAPT microtubule associated protein tau 2 2
MIRT444153 ZNF701 zinc finger protein 701 2 2
MIRT444501 ZNF525 zinc finger protein 525 2 2
MIRT445203 CRYBG3 crystallin beta-gamma domain containing 3 2 2
MIRT447064 MCC mutated in colorectal cancers 2 4
MIRT448126 CCDC80 coiled-coil domain containing 80 2 2
MIRT460408 TNFRSF10B TNF receptor superfamily member 10b 2 4
MIRT462941 ZNF800 zinc finger protein 800 2 12
MIRT463576 ZBTB38 zinc finger and BTB domain containing 38 2 2
MIRT466375 TGOLN2 trans-golgi network protein 2 2 4
MIRT469271 RHOB ras homolog family member B 2 8
MIRT469301 RGS16 regulator of G protein signaling 16 2 2
MIRT469804 RAB14 RAB14, member RAS oncogene family 2 2
MIRT470063 PTGES2 prostaglandin E synthase 2 2 2
MIRT470994 PITPNA phosphatidylinositol transfer protein alpha 2 2
MIRT474951 KCTD10 potassium channel tetramerization domain containing 10 2 4
MIRT475189 IMPDH1P11 inosine monophosphate dehydrogenase 1 pseudogene 11 2 6
MIRT475864 H3F3C H3 histone family member 3C 2 10
MIRT475898 H3F3B H3 histone family member 3B 2 8
MIRT481940 ANKRD11 ankyrin repeat domain 11 2 2
MIRT485556 FOXQ1 forkhead box Q1 2 2
MIRT491004 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT492192 SOCS1 suppressor of cytokine signaling 1 2 4
MIRT493272 LPP LIM domain containing preferred translocation partner in lipoma 2 2
MIRT495273 NICN1 nicolin 1 2 4
MIRT495675 PRKD3 protein kinase D3 2 2
MIRT497541 PPTC7 PTC7 protein phosphatase homolog 2 2
MIRT500398 ZMAT3 zinc finger matrin-type 3 2 8
MIRT500484 ZBTB4 zinc finger and BTB domain containing 4 2 6
MIRT500586 UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 2 4
MIRT500635 TUBB2A tubulin beta 2A class IIa 2 8
MIRT501641 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT501769 NRBF2 nuclear receptor binding factor 2 2 6
MIRT503666 SLC46A1 solute carrier family 46 member 1 2 2
MIRT504322 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT505177 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT506341 NUP54 nucleoporin 54 2 6
MIRT506435 NACC2 NACC family member 2 2 2
MIRT506667 LZIC leucine zipper and CTNNBIP1 domain containing 2 4
MIRT510974 PFN2 profilin 2 2 6
MIRT511142 MRPL17 mitochondrial ribosomal protein L17 2 8
MIRT512601 EFCAB1 EF-hand calcium binding domain 1 2 4
MIRT521037 SLC30A4 solute carrier family 30 member 4 2 2
MIRT525736 SOD2 superoxide dismutase 2 2 2
MIRT526751 GAS7 growth arrest specific 7 2 2
MIRT526903 ZNF772 zinc finger protein 772 2 6
MIRT527346 FAM69C family with sequence similarity 69 member C 2 2
MIRT531901 GLP2R glucagon like peptide 2 receptor 2 2
MIRT532367 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT534253 SLC12A7 solute carrier family 12 member 7 2 2
MIRT534744 RAVER2 ribonucleoprotein, PTB binding 2 2 4
MIRT535341 PFN1 profilin 1 2 2
MIRT535972 MESDC1 talin rod domain containing 1 2 2
MIRT536508 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT536885 HIC2 HIC ZBTB transcriptional repressor 2 2 2
MIRT537039 GRAMD4 GRAM domain containing 4 2 2
MIRT537425 FBXL7 F-box and leucine rich repeat protein 7 2 2
MIRT544578 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT546423 SNX5 sorting nexin 5 2 2
MIRT546754 RLIM ring finger protein, LIM domain interacting 2 2
MIRT547985 HCFC2 host cell factor C2 2 4
MIRT548408 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 2
MIRT549445 ACSL4 acyl-CoA synthetase long chain family member 4 2 2
MIRT549671 ZNF598 zinc finger protein 598 2 2
MIRT550526 MYZAP myocardial zonula adherens protein 2 2
MIRT551214 CIDEC cell death inducing DFFA like effector c 2 2
MIRT552307 ZXDA zinc finger, X-linked, duplicated A 2 4
MIRT552430 ZNF460 zinc finger protein 460 2 2
MIRT553198 UBE2A ubiquitin conjugating enzyme E2 A 2 2
MIRT553337 TRPC3 transient receptor potential cation channel subfamily C member 3 2 4
MIRT554807 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT555180 PRUNE2 prune homolog 2 2 2
MIRT556151 MECP2 methyl-CpG binding protein 2 2 2
MIRT557863 FGFR1OP FGFR1 oncogene partner 2 2
MIRT562085 KIAA0895 KIAA0895 2 2
MIRT563332 RPLP0 ribosomal protein lateral stalk subunit P0 2 2
MIRT565309 TMEM41A transmembrane protein 41A 2 2
MIRT566135 RACGAP1 Rac GTPase activating protein 1 2 2
MIRT567024 KLHL15 kelch like family member 15 2 2
MIRT567242 HSPA13 heat shock protein family A (Hsp70) member 13 2 2
MIRT568560 AKAP10 A-kinase anchoring protein 10 2 2
MIRT570683 FZD5 frizzled class receptor 5 2 2
MIRT572221 BTN3A3 butyrophilin subfamily 3 member A3 2 2
MIRT573305 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT575743 Zfp618 zinc finger protein 618 1 1
MIRT613461 B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 2 2
MIRT614734 STAT5A signal transducer and activator of transcription 5A 2 2
MIRT615118 BCL11B B-cell CLL/lymphoma 11B 2 2
MIRT623238 MLLT6 MLLT6, PHD finger containing 2 2
MIRT623487 KCTD11 potassium channel tetramerization domain containing 11 2 2
MIRT623990 FAM104A family with sequence similarity 104 member A 2 2
MIRT624011 EPHB1 EPH receptor B1 2 2
MIRT626278 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT631416 CRLS1 cardiolipin synthase 1 2 4
MIRT641135 ZBTB33 zinc finger and BTB domain containing 33 2 2
MIRT647830 RAB23 RAB23, member RAS oncogene family 2 2
MIRT649064 HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 2 2
MIRT650284 PYCARD PYD and CARD domain containing 2 2
MIRT651512 WNT4 Wnt family member 4 2 2
MIRT651852 UNC5D unc-5 netrin receptor D 2 2
MIRT652215 TRIM33 tripartite motif containing 33 2 2
MIRT654704 PRRC2B proline rich coiled-coil 2B 2 2
MIRT656793 KNTC1 kinetochore associated 1 2 2
MIRT656926 KIAA1462 junctional cadherin 5 associated 2 2
MIRT659158 DCTN5 dynactin subunit 5 2 2
MIRT663086 METTL10 EEF1A lysine methyltransferase 2 2 2
MIRT676044 AUTS8 Autism, susceptibility to, 8 2 2
MIRT680129 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT689531 KIAA0513 KIAA0513 2 2
MIRT691474 FOXRED2 FAD dependent oxidoreductase domain containing 2 2 2
MIRT692505 SPIN4 spindlin family member 4 2 2
MIRT702405 KITLG KIT ligand 2 2
MIRT704532 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT714231 ARMC10 armadillo repeat containing 10 2 2
MIRT718761 HOOK3 hook microtubule tethering protein 3 2 2
MIRT725422 HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 2 2
MIRT732176 PIK3C2A phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha 4 1
MIRT732272 CCL2 C-C motif chemokine ligand 2 2 1
MIRT732706 GZMB granzyme B 3 0
MIRT735791 CCR6 C-C motif chemokine receptor 6 3 0
MIRT756341 MMP2 matrix metallopeptidase 2 2 1
MIRT756342 MMP9 matrix metallopeptidase 9 2 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-518a-5p (-)-eburnamonine 71203 NSC322920 sensitive
hsa-miR-518a-5p (1'R,3'S,3'aS,8'bS)-1',3'-diphenylspiro[1,3-dihydroindene-2,2'-3,3a,4,8b-tetrahydro-1H-cyclopenta[a]indene]-1,4'-diol 385850 NSC677249 sensitive
hsa-miR-518a-5p (1-(((2-amino-6-chloro-4-pyrimidinyl)amino)methyl)-3-isopropylcyclobutyl)methanol 385230 NSC676343 sensitive
hsa-miR-518a-5p (10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl) 3-methylidene-2-oxo-6-oxabicyclo[3.1.0]hexane-1-carboxylate 495432 NSC654893 sensitive
hsa-miR-518a-5p (2E)-2-[(3,4-dichlorophenyl)methylidene]-6-[(dimethylamino)methyl]cyclohexan-1-one;hydrochloride 5468455 NSC670688 sensitive
hsa-miR-518a-5p (2e,4e,6z,8e)-n-(1,3-benzodioxol-5-yl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide 24202490 NSC672131 sensitive
hsa-miR-518a-5p (2E,6E)-2,6-bis[(4-bromophenyl)methylidene]cyclohexan-1-one 5716584 NSC632831 sensitive
hsa-miR-518a-5p (2s)-1-[(2-phenylmethoxynaphtho[1,2-f][1,3]benzodioxol-5-yl)methyl]piperidine-2-carboxylic acid 24205345 NSC735209 resistant
hsa-miR-518a-5p (3e)-3-[(2-chloro-1-phenylindol-3-yl)methylidene]-5-methoxy-6-methyl-1h-indol-2-one 5471471 NSC711611 sensitive
hsa-miR-518a-5p (3e)-3-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-1h-indol-2-one 5471419 NSC711074 sensitive
hsa-miR-518a-5p (3e)-5-methoxy-3-[(6-phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-1h-indol-2-one 5471411 NSC711066 sensitive
hsa-miR-518a-5p (3Z)-1,1-dimethyl-3-[5-sulfanylidene-4-[(3,4,5-trimethoxyphenyl)methyl]-1,2,4-dithiazolidin-3-ylidene]thiourea 5914108 NSC645621 sensitive
hsa-miR-518a-5p (3z)-5-chloro-3-[(2,6-dimethylimidazo[2,1-b][1,3,4]thiadiazol-5-yl)methylidene]-1h-indol-2-one 24205825 NSC736807 sensitive
hsa-miR-518a-5p (4-methoxyphenyl)(2,3,4-trimethoxyphenyl)methanone 240478 NSC46683 sensitive
hsa-miR-518a-5p (4aR,9aR)-9-(4-methylphenyl)sulfonyl-3,4,4a,9a-tetrahydrocarbazole 372866 NSC648556 sensitive
hsa-miR-518a-5p (4e)-4-(3h-1,3-benzothiazol-2-ylidene)-1-[4-(difluoromethylsulfanyl)phenyl]-5-iminopyrrolidin-2-one 135543874 NSC744116 sensitive
hsa-miR-518a-5p (4S,5R)-4-(2-methylpropyl)-3-[(1R)-1-phenylethyl]-5-phenylmethoxyoxathiazinane 2,2-dioxide 390837 NSC688895 sensitive
hsa-miR-518a-5p (5E)-3-(4-chlorophenyl)-5-[(3-phenoxyphenyl)methylidene]-2-phenyl-1,3-thiazolidin-4-one 5470253 NSC699081 sensitive
hsa-miR-518a-5p (5E)-3-(4-methoxyphenyl)-1,1-dioxo-2-phenyl-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-4-one 5470267 NSC699095 sensitive
hsa-miR-518a-5p (5e)-3-benzyl-5-benzylidene-2-(3,4,5-trimethoxyphenyl)-1,3-thiazolidin-4-one 5470510 NSC702359 sensitive
hsa-miR-518a-5p (5z)-3-[4-benzoyl-2-[(4z)-5-oxo-2-phenyl-4-[(3,4,5-trimethoxyphenyl)methylidene]imidazol-1-yl]phenyl]-2-phenyl-5-[(3,4,5-trimethoxyphenyl)methylidene]imidazol-4-one NSC711885 sensitive
hsa-miR-518a-5p (6-acetamido-7-methyl-5,8-dioxo-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazol-3-yl) 2-methoxyacetate 374010 NSC651084 sensitive
hsa-miR-518a-5p (6aS)-3-[5-[4-(2-diethoxyphosphorylethyl)piperazin-1-yl]pentoxy]-2-methoxy-6a,7,8,9-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-11-one 25113728 NSC744025 sensitive
hsa-miR-518a-5p (7-acetamido-2-acetyloxy-1-methoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-3-yl) acetate 435732 NSC374980 sensitive
hsa-miR-518a-5p (7ar)-1,6-bis(4-methoxyphenyl)-7a-phenyltetrahydroimidazo[1,5-b][1,2,4]oxadiazol-2(1h)-one 402882 NSC717189 sensitive
hsa-miR-518a-5p (8R,9S,10R,13S,14S,16E)-10,13-dimethyl-16-[[3-(2-morpholin-4-ylethoxy)phenyl]methylidene]-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,17-dione 24205793 NSC736753 sensitive
hsa-miR-518a-5p (8R,9S,13S,14S,17S)-13-methyl-2-(2,2,2-trifluoroethoxy)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 386444 NSC678473 sensitive
hsa-miR-518a-5p (8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-2-(2,2,2-trifluoroethoxy)-8,9,11,12,14,15,16,17-octahydro-7H-cyclopenta[a]phenanthren-6-one 387663 NSC681684 sensitive
hsa-miR-518a-5p (e)-1-(2,5-dimethoxyphenyl)-3-(2-fluoro-4,5-dihydroxyphenyl)prop-2-en-1-one 5471282 NSC710266 sensitive
hsa-miR-518a-5p (e)-1-(3,5-ditert-butyl-4-hydroxyphenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one 5471156 NSC709100 sensitive
hsa-miR-518a-5p (E)-1-(7-fluoro-3-methylquinoxalin-2-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 45029310 NSC746087 sensitive
hsa-miR-518a-5p (e)-1-(benzenesulfonyl)-3-(2-phenyl-1h-indol-3-yl)prop-2-en-1-one 54613416 NSC749193 sensitive
hsa-miR-518a-5p (E)-1-[4-(quinazolin-4-ylamino)phenyl]-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one 155816064 NSC760015 sensitive
hsa-miR-518a-5p (e)-1-[4-[[4-(4-chloroanilino)-6-(4-fluoroanilino)-1,3,5-triazin-2-yl]amino]phenyl]-3-[4-(dimethylamino)phenyl]prop-2-en-1-one 45028715 NSC743884 sensitive
hsa-miR-518a-5p (e)-1-[4-[[4,6-bis(4-fluoroanilino)-1,3,5-triazin-2-yl]amino]phenyl]-3-(4-methoxyphenyl)prop-2-en-1-one 24205905 NSC737224 sensitive
hsa-miR-518a-5p (E)-3-(6-thiophen-2-ylimidazo[2,1-b][1,3]thiazol-5-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 50908742 NSC750743 sensitive
hsa-miR-518a-5p (E)-3-[4-(dimethylamino)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one 5468166 NSC665694 sensitive
hsa-miR-518a-5p (E)-N-ethyl-3-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)prop-2-enamide 5388754 NSC638409 sensitive
hsa-miR-518a-5p (Z)-3-amino-1-(5-amino-3-phenylpyrazol-1-yl)-3-phenylprop-2-en-1-one 21825201 NSC749518 sensitive
hsa-miR-518a-5p (z) 3,3',4,5-tetramethoxystilbene 5388774 NSC638492 sensitive
hsa-miR-518a-5p .beta.-phenylethyl 2,4,5-trihydroxycinnamate 5933247 NSC666592 sensitive
hsa-miR-518a-5p [(1r,2r,3r,4r,6r,8s,9e,12s,13s,14r,15s)-3,4,6,12,13-pentaacetyloxy-4,8,11,11-tetramethyl-14-(2-methylpropoxy)-7,18-dioxo-19-oxatricyclo[13.4.0.02,6]nonadec-9-en-15-yl] benzoate 5469441 NSC688228 sensitive
hsa-miR-518a-5p [(1s,2s,3r,4s,7r,9s,10s,12r,15s)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2r,3s)-2-hydroxy-3-(3-methylbutanoylamino)-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]h