miRTarBase - #MIRT209910


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pre-miRNA Information
pre-miRNA hsa-mir-4255   
Genomic Coordinates chr1: 37161563 - 37161634
Description Homo sapiens miR-4255 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4255
Sequence 11| CAGUGUUCAGAGAUGGA |27
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1233897815 1 dbSNP
rs993042903 2 dbSNP
rs917388393 8 dbSNP
rs376475884 9 dbSNP
rs1194949138 14 dbSNP
rs946150710 15 dbSNP
Putative Targets

Gene Information
Gene Symbol CTNNB1   
Synonyms CTNNB, EVR7, MRD19, armadillo
Description catenin beta 1
Transcript NM_001904   
Other Transcripts NM_001098210 , NM_001098209   
Expression
Putative miRNA Targets on CTNNB1
3'UTR of CTNNB1
(miRNA target sites are highlighted)		 
>CTNNB1|NM_001904|3'UTR
   1 ATCATCCTTTAGGTAAGAAGTTTTAAAAAGCCAGTTTGGGTAAAATACTTTTACTCTGCCTACAGAACTTCAGAAAGACT
  81 TGGTTGGTAGGGTGGGAGTGGTTTAGGCTATTTGTAAATCTGCCACAAAAACAGGTATATACTTTGAAAGGAGATGTCTT
 161 GGAACATTGGAATGTTCTCAGATTTCTGGTTGTTATGTGATCATGTGTGGAAGTTATTAACTTTAATGTTTTTTGCCACA
 241 GCTTTTGCAACTTAATACTCAAATGAGTAACATTTGCTGTTTTAAACATTAATAGCAGCCTTTCTCTCTTTATACAGCTG
 321 TATTGTCTGAACTTGCATTGTGATTGGCCTGTAGAGTTGCTGAGAGGGCTCGAGGGGTGGGCTGGTATCTCAGAAAGTGC
 401 CTGACACACTAACCAAGCTGAGTTTCCTATGGGAACAATTGAAGTAAACTTTTTGTTCTGGTCCTTTTTGGTCGAGGAGT
 481 AACAATACAAATGGATTTTGGGAGTGACTCAAGAAGTGAAGAATGCACAAGAATGGATCACAAGATGGAATTTATCAAAC
 561 CCTAGCCTTGCTTGTTAAATTTTTTTTTTTTTTTTTTTAAGAATATCTGTAATGGTACTGACTTTGCTTGCTTTGAAGTA
 641 GCTCTTTTTTTTTTTTTTTTTTTTTTTTTGCAGTAACTGTTTTTTAAGTCTCTCGTAGTGTTAAGTTATAGTGAATACTG
 721 CTACAGCAATTTCTAATTTTTAAGAATTGAGTAATGGTGTAGAACACTAATTCATAATCACTCTAATTAATTGTAATCTG
 801 AATAAAGTGTAACAATTGTGTAGCCTTTTTGTATAAAATAGACAAATAGAAAATGGTCCAATTAGTTTCCTTTTTAATAT
 881 GCTTAAAATAAGCAGGTGGATCTATTTCATGTTTTTGATCAAAAACTATTTGGGATATGTATGGGTAGGGTAAATCAGTA
 961 AGAGGTGTTATTTGGAACCTTGTTTTGGACAGTTTACCAGTTGCCTTTTATCCCAAAGTTGTTGTAACCTGCTGTGATAC
1041 GATGCTTCAAGAGAAAATGCGGTTATAAAAAATGGTTCAGAATTAAACTTTTAATTCATTCGATTG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agguagagaCUUGUGAc 5'
                   ||||||| 
Target 5' aatggtgtaGAACACTa 3'
 753 - 769 140.00 -7.10
2 
miRNA  3' agGUAGAGACUUGUGAc 5'
            ::|||: |||||:| 
Target 5' gaTGTCTTGGAACATTg 3'
 153 - 169 139.00 -12.80
3 
miRNA  3' agguagagACUUGUGAc 5'
                  ||||:||| 
Target 5' agttatagTGAATACTg 3'
 704 - 720 129.00 -11.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30115114 15 COSMIC
COSN31592611 170 COSMIC
COSN28793895 323 COSMIC
COSN20090803 575 COSMIC
COSN25884283 581 COSMIC
COSN7608876 584 COSMIC
COSN20098333 599 COSMIC
COSN32061486 599 COSMIC
COSN31530752 642 COSMIC
COSN5044490 692 COSMIC
COSN229624 696 COSMIC
COSN31589472 727 COSMIC
COSN26465525 734 COSMIC
COSN20098335 773 COSMIC
COSN23881587 1049 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs534929095 3 dbSNP
rs1273314076 4 dbSNP
rs933440782 9 dbSNP
rs1296426385 10 dbSNP
rs1336814167 12 dbSNP
rs1450609010 20 dbSNP
rs770959242 21 dbSNP
rs558310764 24 dbSNP
rs1412064512 28 dbSNP
rs116875446 33 dbSNP
rs1172411792 34 dbSNP
rs772282897 35 dbSNP
rs1452193455 38 dbSNP
rs1250181121 49 dbSNP
rs1200052938 52 dbSNP
rs1403316388 53 dbSNP
rs1415266101 57 dbSNP
rs1248821066 64 dbSNP
rs1051936998 65 dbSNP
rs1483658788 71 dbSNP
rs1279716022 72 dbSNP
rs760755242 78 dbSNP
rs1350356319 80 dbSNP
rs1275719674 87 dbSNP
rs1008092126 92 dbSNP
rs1397073915 95 dbSNP
rs1225135840 101 dbSNP
rs1335022752 103 dbSNP
rs1429247737 105 dbSNP
rs1288867440 109 dbSNP
rs536585791 111 dbSNP
rs1037695399 124 dbSNP
rs1311781381 131 dbSNP
rs1432270359 133 dbSNP
rs757375560 138 dbSNP
rs543891516 143 dbSNP
rs899186532 147 dbSNP
rs1184350891 149 dbSNP
rs1473205299 158 dbSNP
rs904720158 165 dbSNP
rs11564479 166 dbSNP
rs146896526 168 dbSNP
rs1234068156 174 dbSNP
rs993480127 178 dbSNP
rs181927582 180 dbSNP
rs767572148 182 dbSNP
rs1273582168 184 dbSNP
rs781585089 188 dbSNP
rs1279421162 189 dbSNP
rs1204835780 192 dbSNP
rs1348738093 195 dbSNP
rs1323352907 197 dbSNP
rs1213370756 206 dbSNP
rs1229958365 209 dbSNP
rs1351055896 213 dbSNP
rs1292650181 217 dbSNP
rs1412823492 218 dbSNP
rs1341814407 221 dbSNP
rs1381312335 222 dbSNP
rs1014253399 223 dbSNP
rs150533740 228 dbSNP
rs377591875 229 dbSNP
rs4135244 229 dbSNP
rs528304493 229 dbSNP
rs1254713454 230 dbSNP
rs1474686436 235 dbSNP
rs1188142509 243 dbSNP
rs1415506016 246 dbSNP
rs1417559416 246 dbSNP
rs1399366442 249 dbSNP
rs1474053708 251 dbSNP
rs1238138657 261 dbSNP
rs1192480550 267 dbSNP
rs1158793565 273 dbSNP
rs1264065976 278 dbSNP
rs1209569207 280 dbSNP
rs1013367216 284 dbSNP
rs1272312208 285 dbSNP
rs1455758346 286 dbSNP
rs1231437643 288 dbSNP
rs1358304765 291 dbSNP
rs546438186 294 dbSNP
rs4135243 297 dbSNP
rs764044761 301 dbSNP
rs1354825607 303 dbSNP
rs1322186404 307 dbSNP
rs4135388 307 dbSNP
rs887165429 308 dbSNP
rs1295407972 309 dbSNP
rs1004302624 310 dbSNP
rs757079403 311 dbSNP
rs1394285850 323 dbSNP
rs34854135 327 dbSNP
rs1016752107 335 dbSNP
rs962548373 336 dbSNP
rs1371429108 337 dbSNP
rs975271178 338 dbSNP
rs1221901302 356 dbSNP
rs925071236 361 dbSNP
rs1028220824 369 dbSNP
rs4135389 373 dbSNP
rs1474495388 375 dbSNP
rs987808747 379 dbSNP
rs1189528428 385 dbSNP
rs1218631851 386 dbSNP
rs1277581746 392 dbSNP
rs1485099523 399 dbSNP
rs143836144 404 dbSNP
rs1210967273 408 dbSNP
rs1211515689 420 dbSNP
rs1238881187 428 dbSNP
rs1468244125 430 dbSNP
rs1453286009 439 dbSNP
rs986451574 440 dbSNP
rs945245739 449 dbSNP
rs1336961341 450 dbSNP
rs1299165531 458 dbSNP
rs1228705629 465 dbSNP
rs571568960 465 dbSNP
rs1369705583 466 dbSNP
rs1442088887 474 dbSNP
rs1438993717 475 dbSNP
rs371800780 480 dbSNP
rs770023254 482 dbSNP
rs1328820914 489 dbSNP
rs1408705624 490 dbSNP
rs375050845 492 dbSNP
rs1169236929 496 dbSNP
rs933595148 518 dbSNP
rs1393455234 519 dbSNP
rs1172390929 522 dbSNP
rs1478913025 526 dbSNP
rs1247066167 527 dbSNP
rs1375358350 528 dbSNP
rs913563301 531 dbSNP
rs1482001500 538 dbSNP
rs1051930657 541 dbSNP
rs1435469820 544 dbSNP
rs1277809991 545 dbSNP
rs1346732963 545 dbSNP
rs1220564679 546 dbSNP
rs966412069 547 dbSNP
rs1314796983 551 dbSNP
rs1279323123 556 dbSNP
rs2953 556 dbSNP
rs1441688511 557 dbSNP
rs1278757412 560 dbSNP
rs1352792507 563 dbSNP
rs943452981 567 dbSNP
rs925064308 573 dbSNP
rs1178593801 574 dbSNP
rs1415244372 574 dbSNP
rs1009260388 575 dbSNP
rs150512515 577 dbSNP
rs768597179 577 dbSNP
rs775453764 577 dbSNP
rs1304604201 580 dbSNP
rs1344789772 580 dbSNP
rs1353709948 580 dbSNP
rs1414670266 580 dbSNP
rs1449041252 580 dbSNP
rs1491039308 580 dbSNP
rs34653633 580 dbSNP
rs570037233 580 dbSNP
rs878950938 580 dbSNP
rs936155080 580 dbSNP
rs4135387 581 dbSNP
rs879228643 582 dbSNP
rs1253368428 583 dbSNP
rs1440966918 585 dbSNP
rs1413866110 587 dbSNP
rs1158776375 599 dbSNP
rs1474831129 599 dbSNP
rs397989315 599 dbSNP
rs1461659178 600 dbSNP
rs1435727373 601 dbSNP
rs971726685 602 dbSNP
rs1183030252 603 dbSNP
rs1233093065 605 dbSNP
rs1459416154 606 dbSNP
rs1241105408 608 dbSNP
rs920309676 608 dbSNP
rs1206410989 610 dbSNP
rs1466559047 614 dbSNP
rs1192117284 617 dbSNP
rs1233228599 619 dbSNP
rs1320379329 620 dbSNP
rs1314982811 623 dbSNP
rs993418097 623 dbSNP
rs1361333943 624 dbSNP
rs1287377437 626 dbSNP
rs1437544899 627 dbSNP
rs1390634522 628 dbSNP
rs1455053885 630 dbSNP
rs1320909972 631 dbSNP
rs1460861756 632 dbSNP
rs1366604159 642 dbSNP
rs1418123163 642 dbSNP
rs1423933928 642 dbSNP
rs1491119084 642 dbSNP
rs1177945256 643 dbSNP
rs1213418185 643 dbSNP
rs1222912683 643 dbSNP
rs1230901926 643 dbSNP
rs1267806973 643 dbSNP
rs1295477616 643 dbSNP
rs1366116475 643 dbSNP
rs1428702147 643 dbSNP
rs1487806774 643 dbSNP
rs1491138983 643 dbSNP
rs1174412872 644 dbSNP
rs1298103696 644 dbSNP
rs1207330730 645 dbSNP
rs1231291886 645 dbSNP
rs1269909040 645 dbSNP
rs1272576640 645 dbSNP
rs1279936068 645 dbSNP
rs1300349688 645 dbSNP
rs1303114167 645 dbSNP
rs1329197568 645 dbSNP
rs1343166808 645 dbSNP
rs1387285052 645 dbSNP
rs1388277340 645 dbSNP
rs1390356811 645 dbSNP
rs1431843279 645 dbSNP
rs1480558296 645 dbSNP
rs1491112914 645 dbSNP
rs201175238 645 dbSNP
rs1349757251 646 dbSNP
rs1491425067 646 dbSNP
rs1409616189 650 dbSNP
rs1329876057 651 dbSNP
rs1305668153 654 dbSNP
rs1402717201 654 dbSNP
rs1431160580 655 dbSNP
rs1448787067 666 dbSNP
rs1172701677 667 dbSNP
rs1323594758 667 dbSNP
rs1370180700 669 dbSNP
rs1341360170 670 dbSNP
rs1379743872 670 dbSNP
rs1464220666 670 dbSNP
rs1470895392 671 dbSNP
rs1158755781 672 dbSNP
rs1419035838 673 dbSNP
rs1184936314 674 dbSNP
rs1250185377 674 dbSNP
rs1276108741 676 dbSNP
rs1336958135 677 dbSNP
rs1483444246 678 dbSNP
rs1256889586 680 dbSNP
rs1347315485 680 dbSNP
rs796633353 680 dbSNP
rs951788997 680 dbSNP
rs1213461401 685 dbSNP
rs887026132 686 dbSNP
rs564295817 687 dbSNP
rs1013482649 689 dbSNP
rs1350636200 695 dbSNP
rs916158221 695 dbSNP
rs549926618 696 dbSNP
rs1252710811 700 dbSNP
rs1393933058 700 dbSNP
rs1173550169 701 dbSNP
rs1469316974 702 dbSNP
rs1162076453 703 dbSNP
rs1410170522 703 dbSNP
rs1473195593 704 dbSNP
rs1417263420 705 dbSNP
rs549906289 709 dbSNP
rs1185463376 710 dbSNP
rs887123899 712 dbSNP
rs1004269992 721 dbSNP
rs1444369650 725 dbSNP
rs1257192096 730 dbSNP
rs1024798088 734 dbSNP
rs1265993853 734 dbSNP
rs1464328138 734 dbSNP
rs772921930 734 dbSNP
rs969600009 736 dbSNP
rs11708064 745 dbSNP
rs1283123354 748 dbSNP
rs1240863966 751 dbSNP
rs1241924776 752 dbSNP
rs1475162380 759 dbSNP
rs1341717568 760 dbSNP
rs1334442538 761 dbSNP
rs1433894477 766 dbSNP
rs1038447782 767 dbSNP
rs1168550062 767 dbSNP
rs1161958551 768 dbSNP
rs16339 768 dbSNP
rs3834205 768 dbSNP
rs71623294 769 dbSNP
rs1473842656 773 dbSNP
rs202194019 774 dbSNP
rs1460023495 775 dbSNP
rs1162541042 776 dbSNP
rs1393368253 777 dbSNP
rs1210315931 778 dbSNP
rs1032468226 781 dbSNP
rs957820074 782 dbSNP
rs72273140 784 dbSNP
rs772744702 796 dbSNP
rs1284261791 798 dbSNP
rs898602973 805 dbSNP
rs1227228273 807 dbSNP
rs1020671424 810 dbSNP
rs1278235334 816 dbSNP
rs1436344388 819 dbSNP
rs1349631656 821 dbSNP
rs1407566043 831 dbSNP
rs1342014949 832 dbSNP
rs1231015883 834 dbSNP
rs996677731 835 dbSNP
rs1336007987 836 dbSNP
rs1167970101 840 dbSNP
rs1428096068 844 dbSNP
rs1392199991 845 dbSNP
rs954923362 845 dbSNP
rs987749889 850 dbSNP
rs1245908382 851 dbSNP
rs145906085 854 dbSNP
rs1798792 858 dbSNP
rs1289975258 866 dbSNP
rs1282833302 869 dbSNP
rs943507491 871 dbSNP
rs973597237 874 dbSNP
rs1446902820 881 dbSNP
rs1028584501 883 dbSNP
rs1228677615 891 dbSNP
rs955280945 891 dbSNP
rs1008581484 894 dbSNP
rs1194015306 895 dbSNP
rs1722851 898 dbSNP
rs1367420200 900 dbSNP
rs1273387830 902 dbSNP
rs1265350399 903 dbSNP
rs1307519748 904 dbSNP
rs148378295 906 dbSNP
rs757981542 912 dbSNP
rs1020590617 918 dbSNP
rs1169532305 920 dbSNP
rs1262068818 921 dbSNP
rs1047705298 927 dbSNP
rs1170523542 927 dbSNP
rs966337442 927 dbSNP
rs1478984569 930 dbSNP
rs895851900 931 dbSNP
rs1181325624 932 dbSNP
rs1481825938 936 dbSNP
rs950070151 937 dbSNP
rs1458263107 938 dbSNP
rs1204799072 939 dbSNP
rs979091883 940 dbSNP
rs1221247870 953 dbSNP
rs1382738665 953 dbSNP
rs925031738 954 dbSNP
rs959149872 959 dbSNP
rs1399992392 960 dbSNP
rs1058355 963 dbSNP
rs991637481 966 dbSNP
rs1288310774 967 dbSNP
rs1408528209 971 dbSNP
rs1298292667 975 dbSNP
rs1447576189 980 dbSNP
rs1046721530 988 dbSNP
rs1336378535 989 dbSNP
rs916067081 991 dbSNP
rs1412383992 997 dbSNP
rs1292360965 1004 dbSNP
rs766685457 1008 dbSNP
rs1413542301 1009 dbSNP
rs950306546 1012 dbSNP
rs1482738481 1013 dbSNP
rs1278094353 1014 dbSNP
rs1211756626 1015 dbSNP
rs535458683 1015 dbSNP
rs1227106093 1016 dbSNP
rs1267873881 1016 dbSNP
rs1046416733 1017 dbSNP
rs1002413521 1018 dbSNP
rs1032210538 1018 dbSNP
rs893558096 1021 dbSNP
rs908821861 1026 dbSNP
rs1350602036 1030 dbSNP
rs1377027689 1031 dbSNP
rs1206166934 1033 dbSNP
rs1288774288 1034 dbSNP
rs1484764320 1037 dbSNP
rs939983498 1038 dbSNP
rs116035162 1041 dbSNP
rs141130241 1042 dbSNP
rs1009342636 1049 dbSNP
rs535312947 1051 dbSNP
rs779688474 1053 dbSNP
rs1020619033 1059 dbSNP
rs1159718903 1061 dbSNP
rs768489723 1062 dbSNP
rs987171759 1067 dbSNP
rs1183291065 1073 dbSNP
rs1444804308 1074 dbSNP
rs1207171553 1081 dbSNP
rs1247802304 1081 dbSNP
rs1361790401 1083 dbSNP
rs1018232584 1085 dbSNP
rs1261868712 1089 dbSNP
rs755525886 1091 dbSNP
rs1320058565 1092 dbSNP
rs890969152 1096 dbSNP
rs539807313 1099 dbSNP
rs150729932 1102 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 1499.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000349496.5 | 3UTR | AACACUAAUUCAUAAUCACUCUAAUUAAUUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000349496.5 | 3UTR | AACACUAAUUCAUAAUCACUCUAAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000349496.5 | 3UTR | AACACUAAUUCAUAAUCACUCUAAUUAAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
79 hsa-miR-4255 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT086447 NABP1 nucleic acid binding protein 1 2 6
MIRT100423 HSPA1B heat shock protein family A (Hsp70) member 1B 2 8
MIRT105339 SLC7A2 solute carrier family 7 member 2 2 4
MIRT107702 CLTA clathrin light chain A 2 2
MIRT173027 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT178507 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT178621 HIAT1 major facilitator superfamily domain containing 14A 2 2
MIRT199032 POLI DNA polymerase iota 2 2
MIRT205179 CPS1 carbamoyl-phosphate synthase 1 2 2
MIRT209910 CTNNB1 catenin beta 1 2 4
MIRT211675 OTUD4 OTU deubiquitinase 4 2 2
MIRT235433 TSEN34 tRNA splicing endonuclease subunit 34 2 2
MIRT235776 CEBPB CCAAT/enhancer binding protein beta 2 2
MIRT259577 KLHL15 kelch like family member 15 2 4
MIRT357964 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT404130 ASB1 ankyrin repeat and SOCS box containing 1 2 2
MIRT405288 ARF1 ADP ribosylation factor 1 2 2
MIRT441596 PSTK phosphoseryl-tRNA kinase 2 2
MIRT442463 SLC25A13 solute carrier family 25 member 13 2 2
MIRT444065 SERPINA4 serpin family A member 4 2 2
MIRT444637 HSBP1 heat shock factor binding protein 1 2 2
MIRT445467 TRIM13 tripartite motif containing 13 2 2
MIRT446874 NBPF3 NBPF member 3 2 2
MIRT446907 RGS5 regulator of G protein signaling 5 2 2
MIRT447575 CDC14B cell division cycle 14B 2 2
MIRT449966 ZNF555 zinc finger protein 555 2 2
MIRT460773 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 2
MIRT463972 WHSC1 nuclear receptor binding SET domain protein 2 2 4
MIRT463986 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT464218 VGLL4 vestigial like family member 4 2 2
MIRT465098 TSC22D3 TSC22 domain family member 3 2 4
MIRT472797 MTMR4 myotubularin related protein 4 2 4
MIRT473488 MCFD2 multiple coagulation factor deficiency 2 2 2
MIRT478690 CSRP2 cysteine and glycine rich protein 2 2 4
MIRT485064 SUCO SUN domain containing ossification factor 2 2
MIRT485459 IVNS1ABP influenza virus NS1A binding protein 2 2
MIRT486630 TBRG1 transforming growth factor beta regulator 1 2 2
MIRT488730 ADPRHL1 ADP-ribosylhydrolase like 1 2 2
MIRT491959 VPS52 VPS52, GARP complex subunit 2 2
MIRT492428 RGL2 ral guanine nucleotide dissociation stimulator like 2 2 2
MIRT493062 MTFR1 mitochondrial fission regulator 1 2 2
MIRT493071 MTCH1 mitochondrial carrier 1 2 2
MIRT493360 KIF5B kinesin family member 5B 2 2
MIRT493831 FRS2 fibroblast growth factor receptor substrate 2 2 6
MIRT494003 ECT2 epithelial cell transforming 2 2 2
MIRT494314 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT497477 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT504636 MFSD8 major facilitator superfamily domain containing 8 2 6
MIRT509229 KIF14 kinesin family member 14 2 6
MIRT532450 PLGRKT plasminogen receptor with a C-terminal lysine 2 2
MIRT534825 RAB30 RAB30, member RAS oncogene family 2 2
MIRT538333 CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 2 2
MIRT543178 FICD FIC domain containing 2 2
MIRT545477 TRIM37 tripartite motif containing 37 2 2
MIRT546476 SLC17A5 solute carrier family 17 member 5 2 2
MIRT548762 CNN3 calponin 3 2 2
MIRT552285 CBY1 chibby family member 1, beta catenin antagonist 2 4
MIRT554059 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT556636 LAMC1 laminin subunit gamma 1 2 2
MIRT557399 H3F3C H3 histone family member 3C 2 2
MIRT563541 RBM41 RNA binding motif protein 41 2 2
MIRT564078 KIAA1191 KIAA1191 2 2
MIRT564709 ZNF322P1 zinc finger protein 322 pseudogene 1 2 2
MIRT565176 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT565495 AZF1 azoospermia factor 1 2 2
MIRT565817 SDCCAG3 serologically defined colon cancer antigen 3 2 2
MIRT566859 LRRC58 leucine rich repeat containing 58 2 2
MIRT567074 KBTBD2 kelch repeat and BTB domain containing 2 2 2
MIRT568433 GDNF glial cell derived neurotrophic factor 2 2
MIRT635098 AKIRIN1 akirin 1 2 2
MIRT638501 NNT nicotinamide nucleotide transhydrogenase 2 2
MIRT651609 WDFY2 WD repeat and FYVE domain containing 2 2 2
MIRT653175 SPPL3 signal peptide peptidase like 3 2 2
MIRT653995 SECISBP2 SECIS binding protein 2 2 2
MIRT656957 KIAA1244 ARFGEF family member 3 3 3
MIRT683841 ZNF682 zinc finger protein 682 2 2
MIRT685223 POTED POTE ankyrin domain family member D 2 2
MIRT716829 PSME4 proteasome activator subunit 4 2 2
MIRT721513 CARHSP1 calcium regulated heat stable protein 1 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4255 Doxorubicin 31703 NSC123127 approved sensitive High Triple-Negative Breast Cancer cell line (MDA-MB-231, MDA-MB-468)
hsa-miR-4255 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4255 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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