miRTarBase - #MIRT214733


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pre-miRNA Information
pre-miRNA hsa-mir-302b   
Genomic Coordinates chr4: 112648485 - 112648557
Description Homo sapiens miR-302b stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-302b-5p
Sequence 11| ACUUUAACAUGGAAGUGCUUUC |32
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN8489942 10 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs771747691 1 dbSNP
rs1413992790 2 dbSNP
rs1287454726 3 dbSNP
rs1407802102 5 dbSNP
rs556661625 8 dbSNP
rs114318553 9 dbSNP
rs183105707 12 dbSNP
rs759066554 13 dbSNP
rs1338196516 15 dbSNP
Putative Targets

Gene Information
Gene Symbol HSPA9   
Synonyms CRP40, CSA, EVPLS, GRP-75, GRP75, HEL-S-124m, HSPA9B, MOT, MOT2, MTHSP75, PBP74, SAAN, SIDBA4
Description heat shock protein family A (Hsp70) member 9
Transcript NM_004134   
Expression
Putative miRNA Targets on HSPA9
3'UTR of HSPA9
(miRNA target sites are highlighted)		 
>HSPA9|NM_004134|3'UTR
   1 TAATAGCAGAAATTTTGAAGCCAGAAGGACAACATATGAAGCTTAGGAGTGAAGAGACTTCCTGAGCAGAAATGGGCGAA
  81 CTTCAGTCTTTTTACTGTGTTTTTGCAGTATTCTATATATAATTTCCTTAATTTGTAAATTTAGTGACCATTAGCTAGTG
 161 ATCATTTAATGGACAGTGATTCTAACAGTATAAAGTTCACAATATTCTATGTCCCTAGCCTGTCATTTTTCAGCTGCATG
 241 TAAAAGGAGGTAGGATGAATTGATCATTATAAAGATTTAACTATTTTATGCTGAAGTGACCATATTTTCAAGGGGTGAAA
 321 CCATCTCGCACACAGCAATGAAGGTAGTCATCCATAGACTTGAAATGAGACCACATATGGGGATGAGATCCTTCTAGTTA
 401 GCCTAGTACTGCTGTACTGGCCTGTATGTACATGGGGTCCTTCAACTGAGGCCTTGCAAGTCAAGCTGGCTGTGCCATGT
 481 TTGTAGATGGGGCAGAGGAATCTAGAACAATGGGAAACTTAGCTATTTATATTAGGTACAGCTATTAAAACAAGGTAGGA
 561 ATGAGGCTAGACCTTTAACTTCCCTAAGGCATACTTTTCTAGCTACCTTCTGCCCTGTGTCTGGCACCTACATCCTTGAT
 641 GATTGTTCTCTTACCCATTCTGGAATTTTTTTTTTTTTAAATAAATACAGAAAGCATCTTGATCTCTTGTTTGTGAGGGG
 721 TGATGCCCTGAGATTTAGCTTCAAGAATATGCCATGGCTCATGCTTCCCATATTTCCCAAAGAGGGAAATACAGGATTTG
 801 CTAACACTGGTTAAAAATGCAAATTCAAGATTTGGAAGGGCTGTTATAATGAAATAATGAGCAGTATCAGCATGTGCAAA
 881 TCTTGTTTGAAGGATTTTATTTTCTCCCCTTAGACCTTTGGTACATTTAGAATCTTGAAAGTTTCTAGATCTCTAACATG
 961 AAAGTTTCTAGATCTCTAACATGAAAGTTTTTAGATCTCTAACATGAAAACCAAGGTGGCTATTTTCAGGTTGCTTTCAG
1041 CTCCAAGTAGAAATAACCAGAATTGGCTTACATTAAAGAAACTGCATCTAGAAATAAGTCCTAAGATACTATTTCTATGG
1121 CTCAAAAATAAAAGGAACCCAGATTTCTTTCCCTA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuuUCGUGAA-GGU----A-CAAUUUca 5'
             || |:|| |:|    | ||||||  
Target 5' tacAGGATTTGCTAACACTGGTTAAAaa 3'
 790 - 817 129.00 -5.70
2 
miRNA  3' cuuucGUGAAGGUACAAUUUCa 5'
               ||  | ||||| |||| 
Target 5' tttttCAGCTGCATGTAAAAGg 3'
 226 - 247 129.00 -8.30
3 
miRNA  3' cuuUCGUGAAGGU--ACA-AUUUCa 5'
             ||:: |||:|   || ||||| 
Target 5' gacAGTGATTCTAACAGTATAAAGt 3'
 172 - 196 125.00 -6.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26585915 21 COSMIC
COSN30109422 28 COSMIC
COSN30506523 73 COSMIC
COSN14141879 78 COSMIC
COSN30152477 86 COSMIC
COSN29462736 101 COSMIC
COSN30169765 141 COSMIC
COSN31567587 274 COSMIC
COSN25494041 597 COSMIC
COSN29249338 618 COSMIC
COSN23161660 665 COSMIC
COSN25495729 712 COSMIC
COSN25495728 774 COSMIC
COSN25556964 1116 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs750023663 1 dbSNP
rs368382143 4 dbSNP
rs1453370780 6 dbSNP
rs375337663 8 dbSNP
rs1159641309 10 dbSNP
rs201871238 11 dbSNP
rs1385293767 15 dbSNP
rs751393378 17 dbSNP
rs764021005 22 dbSNP
rs762960867 24 dbSNP
rs775601741 28 dbSNP
rs765294292 29 dbSNP
rs1031597405 33 dbSNP
rs1015173867 34 dbSNP
rs759551229 37 dbSNP
rs1260962144 38 dbSNP
rs1218308447 41 dbSNP
rs367940640 50 dbSNP
rs1009176634 64 dbSNP
rs1262384683 65 dbSNP
rs1410602988 67 dbSNP
rs1398962334 70 dbSNP
rs1348400920 72 dbSNP
rs1204352847 77 dbSNP
rs534609124 78 dbSNP
rs890095666 80 dbSNP
rs1201384928 86 dbSNP
rs1242056081 91 dbSNP
rs200864424 92 dbSNP
rs770420279 94 dbSNP
rs1472690352 117 dbSNP
rs1050109308 135 dbSNP
rs1190709346 140 dbSNP
rs1362602588 142 dbSNP
rs1470031896 144 dbSNP
rs971289785 149 dbSNP
rs1022827505 150 dbSNP
rs1408749666 155 dbSNP
rs1468487894 156 dbSNP
rs756118383 157 dbSNP
rs570088087 158 dbSNP
rs1251719370 159 dbSNP
rs1393243930 160 dbSNP
rs904269837 162 dbSNP
rs895264520 166 dbSNP
rs1437882474 170 dbSNP
rs1274703947 171 dbSNP
rs1042820695 175 dbSNP
rs1283766386 178 dbSNP
rs1325408886 189 dbSNP
rs1038156613 198 dbSNP
rs1042803 199 dbSNP
rs945870027 202 dbSNP
rs1480732511 213 dbSNP
rs1207657183 215 dbSNP
rs891653001 217 dbSNP
rs768125046 220 dbSNP
rs781728702 221 dbSNP
rs1056953243 222 dbSNP
rs1431962620 229 dbSNP
rs575501030 231 dbSNP
rs938623126 238 dbSNP
rs1176107353 239 dbSNP
rs1424628810 246 dbSNP
rs961395402 247 dbSNP
rs1463666521 248 dbSNP
rs552182553 250 dbSNP
rs886414065 260 dbSNP
rs760062028 268 dbSNP
rs980801518 269 dbSNP
rs1348633421 271 dbSNP
rs1221494945 274 dbSNP
rs530498410 274 dbSNP
rs1307732258 275 dbSNP
rs1229149564 281 dbSNP
rs11032 283 dbSNP
rs1223937598 285 dbSNP
rs1039216770 293 dbSNP
rs1337564713 302 dbSNP
rs1489987918 324 dbSNP
rs943525518 327 dbSNP
rs914337845 328 dbSNP
rs1404921537 332 dbSNP
rs548484188 334 dbSNP
rs1372631326 338 dbSNP
rs766808983 339 dbSNP
rs955752762 344 dbSNP
rs1165504418 345 dbSNP
rs1367397744 346 dbSNP
rs954992890 351 dbSNP
rs530276513 355 dbSNP
rs1029697978 359 dbSNP
rs559991571 369 dbSNP
rs924246781 374 dbSNP
rs1455945097 375 dbSNP
rs182574828 378 dbSNP
rs1292958941 387 dbSNP
rs577627547 395 dbSNP
rs1411936343 401 dbSNP
rs995848768 411 dbSNP
rs1470226094 412 dbSNP
rs747136374 420 dbSNP
rs1357927328 421 dbSNP
rs981084230 426 dbSNP
rs904225344 430 dbSNP
rs1487043042 431 dbSNP
rs1196322540 443 dbSNP
rs971342161 445 dbSNP
rs1021310699 460 dbSNP
rs1185515582 462 dbSNP
rs1215379660 466 dbSNP
rs1326791495 469 dbSNP
rs1383392164 472 dbSNP
rs1009957397 474 dbSNP
rs1162826273 479 dbSNP
rs1022878314 482 dbSNP
rs1012758766 493 dbSNP
rs1224237793 498 dbSNP
rs1286847201 501 dbSNP
rs565120866 505 dbSNP
rs1452823951 508 dbSNP
rs543828649 512 dbSNP
rs1316617468 518 dbSNP
rs1273210802 520 dbSNP
rs938556479 521 dbSNP
rs1245956127 522 dbSNP
rs772714026 530 dbSNP
rs1319214873 534 dbSNP
rs769523466 536 dbSNP
rs1044742828 546 dbSNP
rs1006688878 551 dbSNP
rs1328143410 554 dbSNP
rs1433376907 565 dbSNP
rs886512992 573 dbSNP
rs1444052984 582 dbSNP
rs1160476244 585 dbSNP
rs948068218 590 dbSNP
rs576456179 594 dbSNP
rs1156669210 605 dbSNP
rs973462254 608 dbSNP
rs1042981 610 dbSNP
rs7306 617 dbSNP
rs41296457 620 dbSNP
rs987660306 621 dbSNP
rs1298207979 623 dbSNP
rs1253295324 628 dbSNP
rs1039229296 630 dbSNP
rs1195061940 630 dbSNP
rs1306824274 634 dbSNP
rs723711 635 dbSNP
rs914702928 638 dbSNP
rs552773039 639 dbSNP
rs975423761 644 dbSNP
rs1054226573 646 dbSNP
rs1481614065 648 dbSNP
rs1216218045 655 dbSNP
rs1411026186 657 dbSNP
rs934426948 665 dbSNP
rs1426797576 670 dbSNP
rs534573179 678 dbSNP
rs1346647581 679 dbSNP
rs1355771410 679 dbSNP
rs1406295627 679 dbSNP
rs531663622 679 dbSNP
rs924353035 680 dbSNP
rs1407168160 682 dbSNP
rs551312350 682 dbSNP
rs1305936278 686 dbSNP
rs981136495 686 dbSNP
rs570439434 688 dbSNP
rs758660828 688 dbSNP
rs1305814563 689 dbSNP
rs1202405188 698 dbSNP
rs558263287 700 dbSNP
rs537086702 703 dbSNP
rs1289868748 709 dbSNP
rs991790853 709 dbSNP
rs1201334618 712 dbSNP
rs1002702600 713 dbSNP
rs1477532396 713 dbSNP
rs1168125539 717 dbSNP
rs1433286669 717 dbSNP
rs1421073595 751 dbSNP
rs189943828 758 dbSNP
rs1167358808 761 dbSNP
rs1366744322 762 dbSNP
rs1334067442 765 dbSNP
rs1427032230 768 dbSNP
rs111413914 770 dbSNP
rs1301754877 770 dbSNP
rs1395088241 783 dbSNP
rs995442520 785 dbSNP
rs1175156028 792 dbSNP
rs1272115995 792 dbSNP
rs982618216 794 dbSNP
rs138190582 797 dbSNP
rs1026349154 799 dbSNP
rs1360083239 800 dbSNP
rs1224627176 802 dbSNP
rs997481750 805 dbSNP
rs901815409 822 dbSNP
rs545939942 847 dbSNP
rs1193580466 856 dbSNP
rs1008198038 859 dbSNP
rs1474187721 861 dbSNP
rs893376834 864 dbSNP
rs1427172486 871 dbSNP
rs1162196895 879 dbSNP
rs1390514141 885 dbSNP
rs1401684163 885 dbSNP
rs1209989260 899 dbSNP
rs1052308930 902 dbSNP
rs1343667531 907 dbSNP
rs750218965 910 dbSNP
rs1423325984 912 dbSNP
rs1315912205 914 dbSNP
rs879683453 922 dbSNP
rs1385071096 924 dbSNP
rs1248147500 930 dbSNP
rs1055070812 937 dbSNP
rs779991863 950 dbSNP
rs933485651 959 dbSNP
rs1205513369 960 dbSNP
rs934835979 963 dbSNP
rs367563 968 dbSNP
rs185873014 969 dbSNP
rs949717910 974 dbSNP
rs1296555461 975 dbSNP
rs1243270990 978 dbSNP
rs974991845 987 dbSNP
rs41296461 991 dbSNP
rs553776968 991 dbSNP
rs1470766104 999 dbSNP
rs1160660560 1000 dbSNP
rs745717177 1009 dbSNP
rs759130428 1010 dbSNP
rs914198388 1011 dbSNP
rs1333519596 1012 dbSNP
rs1450568495 1012 dbSNP
rs543443768 1013 dbSNP
rs991156067 1016 dbSNP
rs988432284 1017 dbSNP
rs955741213 1019 dbSNP
rs1326787944 1021 dbSNP
rs1227442171 1024 dbSNP
rs1035434115 1026 dbSNP
rs1462340454 1029 dbSNP
rs1284127479 1043 dbSNP
rs1415889974 1053 dbSNP
rs941298932 1064 dbSNP
rs1375540055 1065 dbSNP
rs1184588698 1068 dbSNP
rs531691352 1071 dbSNP
rs561130826 1072 dbSNP
rs1177536026 1076 dbSNP
rs746479896 1076 dbSNP
rs1172130036 1084 dbSNP
rs909799585 1084 dbSNP
rs1397282296 1087 dbSNP
rs983055344 1098 dbSNP
rs1353623323 1101 dbSNP
rs951184719 1110 dbSNP
rs1430090176 1111 dbSNP
rs542686436 1119 dbSNP
rs976117345 1120 dbSNP
rs966031919 1127 dbSNP
rs1409012842 1139 dbSNP
rs1475523038 1140 dbSNP
rs576968540 1142 dbSNP
rs1007555002 1146 dbSNP
rs1180189942 1152 dbSNP
rs572224581 1155 dbSNP
rs1004873292 1158 dbSNP
rs779505158 1160 dbSNP
rs1198124521 1162 dbSNP
rs867161192 1169 dbSNP
rs999024297 1172 dbSNP
rs1200602727 1175 dbSNP
rs1271484805 1179 dbSNP
rs1198397212 1183 dbSNP
rs1479610151 1183 dbSNP
rs1373758799 1184 dbSNP
rs1206804333 1185 dbSNP
rs199520701 1188 dbSNP
rs1368644533 1189 dbSNP
rs1320937282 1190 dbSNP
rs888724394 1193 dbSNP
rs1303607828 1199 dbSNP
rs552726502 1200 dbSNP
rs1289546942 1203 dbSNP
rs1300133510 1210 dbSNP
rs1326615040 1211 dbSNP
rs1229007431 1213 dbSNP
rs540872879 1221 dbSNP
rs1235815327 1222 dbSNP
rs1491236006 1224 dbSNP
rs1487692104 1225 dbSNP
rs1491141419 1225 dbSNP
rs182179839 1226 dbSNP
rs922088347 1228 dbSNP
rs1357991411 1229 dbSNP
rs1039179094 1236 dbSNP
rs1191123477 1242 dbSNP
rs777854806 1251 dbSNP
rs1389627318 1252 dbSNP
rs947593794 1258 dbSNP
rs558773722 1262 dbSNP
rs1044930412 1268 dbSNP
rs756416590 1283 dbSNP
rs989052577 1286 dbSNP
rs868102833 1291 dbSNP
rs74490121 1297 dbSNP
rs955690682 1300 dbSNP
rs1055907925 1301 dbSNP
rs1385224408 1304 dbSNP
rs1383553610 1306 dbSNP
rs1294836003 1308 dbSNP
rs941029247 1309 dbSNP
rs1247396060 1325 dbSNP
rs1298424549 1327 dbSNP
rs1463155223 1328 dbSNP
rs569604681 1330 dbSNP
rs554618591 1338 dbSNP
rs1221312082 1343 dbSNP
rs981186460 1344 dbSNP
rs557597783 1347 dbSNP
rs1207043998 1350 dbSNP
rs1247546572 1352 dbSNP
rs1461804256 1353 dbSNP
rs752875738 1354 dbSNP
rs536335994 1355 dbSNP
rs1421929276 1356 dbSNP
rs929831670 1359 dbSNP
rs1022759694 1365 dbSNP
rs189951276 1366 dbSNP
rs548008229 1367 dbSNP
rs1455064433 1369 dbSNP
rs962564766 1377 dbSNP
rs1015501045 1382 dbSNP
rs1452754971 1397 dbSNP
rs1338058124 1398 dbSNP
rs1377630781 1399 dbSNP
rs1228249431 1403 dbSNP
rs976544298 1404 dbSNP
rs1319084036 1407 dbSNP
rs966125415 1410 dbSNP
rs1267780285 1418 dbSNP
rs1324481183 1419 dbSNP
rs910628141 1420 dbSNP
rs532794770 1424 dbSNP
rs1235799030 1426 dbSNP
rs1156786302 1429 dbSNP
rs1181182960 1430 dbSNP
rs1418581010 1434 dbSNP
rs1251281919 1435 dbSNP
rs1473468036 1442 dbSNP
rs1156624080 1443 dbSNP
rs1410786117 1446 dbSNP
rs567284588 1455 dbSNP
rs1469934724 1456 dbSNP
rs571757049 1457 dbSNP
rs1487654393 1461 dbSNP
rs1252611630 1465 dbSNP
rs1299213791 1477 dbSNP
rs957353298 1486 dbSNP
rs886412928 1489 dbSNP
rs750343659 1496 dbSNP
rs187614338 1500 dbSNP
rs1408413734 1502 dbSNP
rs1030753632 1507 dbSNP
rs531935361 1517 dbSNP
rs1337338378 1524 dbSNP
rs999078347 1525 dbSNP
rs1225562768 1526 dbSNP
rs900580409 1531 dbSNP
rs1311644410 1532 dbSNP
rs1266788999 1539 dbSNP
rs371198130 1541 dbSNP
rs542649586 1543 dbSNP
rs947546732 1545 dbSNP
rs41296463 1548 dbSNP
rs1365129876 1549 dbSNP
rs762062786 1550 dbSNP
rs1422498082 1554 dbSNP
rs1413446506 1559 dbSNP
rs894250601 1561 dbSNP
rs1170478409 1562 dbSNP
rs1055516523 1563 dbSNP
rs1428313233 1564 dbSNP
rs1005634410 1566 dbSNP
rs1441381107 1567 dbSNP
rs1346513613 1568 dbSNP
rs1407036669 1577 dbSNP
rs1273327161 1580 dbSNP
rs934923266 1581 dbSNP
rs1396317164 1583 dbSNP
rs888098167 1588 dbSNP
rs1452901824 1589 dbSNP
rs1364284115 1590 dbSNP
rs1202922923 1592 dbSNP
rs1273709320 1592 dbSNP
rs182014286 1594 dbSNP
rs1490444023 1595 dbSNP
rs1223447326 1600 dbSNP
rs1244648102 1601 dbSNP
rs1477459482 1603 dbSNP
rs981516758 1609 dbSNP
rs1046981092 1616 dbSNP
rs1431502230 1621 dbSNP
rs374151558 1623 dbSNP
rs1168470556 1624 dbSNP
rs10063809 1625 dbSNP
rs756935535 1626 dbSNP
rs915638595 1629 dbSNP
rs1299988703 1633 dbSNP
rs973841436 1641 dbSNP
rs1040888652 1645 dbSNP
rs1246524101 1648 dbSNP
rs942500531 1649 dbSNP
rs1015448936 1650 dbSNP
rs1229837041 1657 dbSNP
rs868046642 1661 dbSNP
rs767039197 1664 dbSNP
rs910629010 1666 dbSNP
rs576921780 1672 dbSNP
rs138828606 1677 dbSNP
rs1463183581 1680 dbSNP
rs753677741 1690 dbSNP
rs957614065 1693 dbSNP
rs747575731 1694 dbSNP
rs543667276 1696 dbSNP
rs1161897653 1699 dbSNP
rs1413510157 1699 dbSNP
rs926003615 1701 dbSNP
rs568783436 1704 dbSNP
rs1386679566 1725 dbSNP
rs967661739 1726 dbSNP
rs1341002788 1728 dbSNP
rs554943459 1731 dbSNP
rs576291510 1733 dbSNP
rs1282274709 1746 dbSNP
rs1355336155 1751 dbSNP
rs1228732735 1760 dbSNP
rs1014439127 1763 dbSNP
rs1269648860 1772 dbSNP
rs1326569299 1774 dbSNP
rs958864024 1775 dbSNP
rs146042327 1782 dbSNP
rs750862638 1783 dbSNP
rs888181472 1784 dbSNP
rs1046742115 1785 dbSNP
rs1470736029 1787 dbSNP
rs536301062 1790 dbSNP
rs1410055064 1791 dbSNP
rs1456851737 1794 dbSNP
rs901103781 1797 dbSNP
rs1046015686 1802 dbSNP
rs1290503418 1803 dbSNP
rs1397752688 1805 dbSNP
rs948371483 1807 dbSNP
rs761010761 1808 dbSNP
rs1339752439 1813 dbSNP
rs572163574 1814 dbSNP
rs973789080 1815 dbSNP
rs1040898491 1819 dbSNP
rs1256125040 1819 dbSNP
rs1346467240 1821 dbSNP
rs941096795 1821 dbSNP
rs908333976 1833 dbSNP
rs1438842443 1845 dbSNP
rs942544405 1846 dbSNP
rs1250063804 1853 dbSNP
rs889597435 1859 dbSNP
rs553862628 1861 dbSNP
rs955267704 1863 dbSNP
rs1054014214 1865 dbSNP
rs1379543106 1876 dbSNP
rs1464625394 1885 dbSNP
rs1455786012 1886 dbSNP
rs1388517208 1893 dbSNP
rs1401414132 1895 dbSNP
rs535052040 1899 dbSNP
rs34053612 1911 dbSNP
rs1368446168 1914 dbSNP
rs538359730 1915 dbSNP
rs977453535 1916 dbSNP
rs142221229 1918 dbSNP
rs1199174692 1919 dbSNP
rs1017574539 1925 dbSNP
rs1273664400 1926 dbSNP
rs255999 1927 dbSNP
rs1207907981 1929 dbSNP
rs1210947423 1939 dbSNP
rs1482949072 1941 dbSNP
rs993056714 1942 dbSNP
rs959142365 1943 dbSNP
rs1431586720 1950 dbSNP
rs1268035923 1956 dbSNP
rs1226444701 1958 dbSNP
rs999422343 1968 dbSNP
rs1326740074 1970 dbSNP
rs1450061077 1976 dbSNP
rs1170379559 1980 dbSNP
rs907398048 1984 dbSNP
rs1293840431 1989 dbSNP
rs1392438146 1992 dbSNP
rs1034553858 1994 dbSNP
rs1365267718 1995 dbSNP
rs1231314496 2000 dbSNP
rs1296068175 2001 dbSNP
rs984680084 2004 dbSNP
rs1245990459 2007 dbSNP
rs772076730 2009 dbSNP
rs1487660451 2013 dbSNP
rs1209441596 2015 dbSNP
rs778949591 2016 dbSNP
rs1248768352 2019 dbSNP
rs1313603594 2020 dbSNP
rs894112131 2027 dbSNP
rs952535222 2028 dbSNP
rs1388265352 2031 dbSNP
rs1448726760 2036 dbSNP
rs1165303964 2039 dbSNP
rs1038042451 2040 dbSNP
rs1369009626 2041 dbSNP
rs768109982 2044 dbSNP
rs759747948 2055 dbSNP
rs760230483 2062 dbSNP
rs1456115361 2066 dbSNP
rs550293620 2069 dbSNP
rs775377618 2072 dbSNP
rs1388848978 2075 dbSNP
rs1462816394 2077 dbSNP
rs552124735 2081 dbSNP
rs567909428 2082 dbSNP
rs1046838299 2083 dbSNP
rs1397106557 2085 dbSNP
rs548954454 2099 dbSNP
rs1006835958 2108 dbSNP
rs374529151 2121 dbSNP
rs922481759 2129 dbSNP
rs1269034739 2130 dbSNP
rs1331415962 2136 dbSNP
rs975709656 2141 dbSNP
rs889681773 2144 dbSNP
rs1315890639 2158 dbSNP
rs1485537957 2169 dbSNP
rs745396136 2171 dbSNP
rs910513797 2181 dbSNP
rs1258062894 2187 dbSNP
rs255998 2189 dbSNP
rs148065389 2198 dbSNP
rs1412255743 2199 dbSNP
rs1188125515 2201 dbSNP
rs904616400 2202 dbSNP
rs1387246018 2203 dbSNP
rs76874909 2205 dbSNP
rs1305142365 2207 dbSNP
rs745638766 2209 dbSNP
rs1395822737 2210 dbSNP
rs778511532 2211 dbSNP
rs1352635161 2213 dbSNP
rs971942515 2220 dbSNP
rs255997 2221 dbSNP
rs1013546908 2222 dbSNP
rs188374576 2223 dbSNP
rs1038666406 2237 dbSNP
rs1005207164 2241 dbSNP
rs753052664 2242 dbSNP
rs886796267 2246 dbSNP
rs937633685 2251 dbSNP
rs933770511 2252 dbSNP
rs927536657 2254 dbSNP
rs1363915557 2255 dbSNP
rs1333986176 2256 dbSNP
rs922396454 2256 dbSNP
rs1039543571 2259 dbSNP
rs915151503 2263 dbSNP
rs942576313 2263 dbSNP
rs1372764058 2264 dbSNP
rs1491385560 2266 dbSNP
rs984341624 2266 dbSNP
rs989385888 2266 dbSNP
rs1398877059 2267 dbSNP
rs1491182504 2267 dbSNP
rs1299272182 2269 dbSNP
rs1310442435 2274 dbSNP
rs952950246 2275 dbSNP
rs1210036963 2281 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796039. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796040. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796039
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000297185.3 | 3UTR | UUGGCUUACAUUAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796040
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000297185.3 | 3UTR | UUGGCUUACAUUAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.623 5.7e-4 0.658 2.4e-4 24 Click to see details
GSE15076 Monocyte-derived dendritic cells -0.974 1.3e-2 -0.800 1.0e-1 4 Click to see details
GSE42095 Differentiated embryonic stem cells 0.457 1.4e-2 0.479 1.0e-2 23 Click to see details
GSE28260 Renal cortex and medulla -0.443 6.5e-2 -0.467 5.4e-2 13 Click to see details
GSE26953 Aortic valvular endothelial cells -0.294 8.2e-2 -0.149 2.4e-1 24 Click to see details
GSE14794 Lymphoblastoid cells 0.142 9.1e-2 0.184 4.1e-2 90 Click to see details
GSE21849 B cell lymphoma -0.245 1.0e-1 0.162 2.0e-1 29 Click to see details
GSE17306 Multiple myeloma -0.17 1.2e-1 0.228 5.8e-2 49 Click to see details
GSE27834 Pluripotent stem cells 0.303 1.3e-1 0.432 4.7e-2 16 Click to see details
GSE17498 Multiple myeloma 0.146 1.8e-1 0.106 2.6e-1 40 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.159 2.5e-1 -0.110 3.2e-1 20 Click to see details
GSE19350 CNS germ cell tumors -0.207 2.6e-1 0.105 3.7e-1 12 Click to see details
GSE21687 Ependynoma primary tumors -0.047 3.6e-1 -0.035 3.9e-1 64 Click to see details
GSE38226 Liver fibrosis 0.083 3.6e-1 0.068 3.8e-1 21 Click to see details
GSE38974 Chronic obstructive pulmonary disease -0.03 4.4e-1 -0.130 2.7e-1 25 Click to see details
GSE32688 Pancreatic cancer 0.01 4.8e-1 0.096 3.0e-1 32 Click to see details
GSE32688 Pancreatic cancer 0.01 4.8e-1 0.096 3.0e-1 32 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
109 hsa-miR-302b-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT088427 LCLAT1 lysocardiolipin acyltransferase 1 2 4
MIRT142406 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT162006 TFRC transferrin receptor 2 2
MIRT170893 PURB purine rich element binding protein B 2 2
MIRT203348 CCNT2 cyclin T2 2 4
MIRT207353 TGOLN2 trans-golgi network protein 2 2 2
MIRT208232 CNBP CCHC-type zinc finger nucleic acid binding protein 2 4
MIRT214733 HSPA9 heat shock protein family A (Hsp70) member 9 2 2
MIRT254842 NUP50 nucleoporin 50 2 2
MIRT257285 FOXC1 forkhead box C1 2 2
MIRT338890 LLPH LLP homolog, long-term synaptic facilitation 2 2
MIRT400032 USP37 ubiquitin specific peptidase 37 2 2
MIRT404031 ATP9A ATPase phospholipid transporting 9A (putative) 2 8
MIRT405843 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 2
MIRT445847 FPGT fucose-1-phosphate guanylyltransferase 2 2
MIRT446350 EML6 echinoderm microtubule associated protein like 6 2 2
MIRT446649 BTBD7 BTB domain containing 7 2 2
MIRT447925 SCRN1 secernin 1 2 2
MIRT448575 PLCG1 phospholipase C gamma 1 2 2
MIRT463616 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT465782 TMOD3 tropomodulin 3 2 2
MIRT470261 PRR14L proline rich 14 like 2 2
MIRT471090 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta 2 2
MIRT475612 HMGB1 high mobility group box 1 2 2
MIRT476824 FNDC3A fibronectin type III domain containing 3A 2 2
MIRT483107 TYRP1 tyrosinase related protein 1 2 10
MIRT500537 XPO4 exportin 4 2 2
MIRT502525 EPHA2 EPH receptor A2 2 4
MIRT510989 PER1 period circadian clock 1 2 4
MIRT512540 ZNF793 zinc finger protein 793 2 4
MIRT513868 HOXA5 homeobox A5 2 2
MIRT520756 TFDP1 transcription factor Dp-1 2 6
MIRT524304 CTC1 CST telomere replication complex component 1 2 8
MIRT526306 JAKMIP2 janus kinase and microtubule interacting protein 2 2 2
MIRT526378 LSAMP limbic system-associated membrane protein 2 2
MIRT527438 COL4A3 collagen type IV alpha 3 chain 2 2
MIRT527511 ZNF134 zinc finger protein 134 2 2
MIRT528068 HES2 hes family bHLH transcription factor 2 2 2
MIRT528367 ZMYM1 zinc finger MYM-type containing 1 2 4
MIRT531804 TFCP2L1 transcription factor CP2 like 1 2 2
MIRT532323 DUSP4 dual specificity phosphatase 4 2 2
MIRT532431 DHX33 DEAH-box helicase 33 2 2
MIRT534523 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT536660 INIP INTS3 and NABP interacting protein 2 2
MIRT538488 CLOCK clock circadian regulator 2 2
MIRT538593 CDK6 cyclin dependent kinase 6 2 2
MIRT539706 EIF3H eukaryotic translation initiation factor 3 subunit H 2 2
MIRT540306 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 2
MIRT546892 PURA purine rich element binding protein A 2 2
MIRT552738 YRDC yrdC N6-threonylcarbamoyltransferase domain containing 2 2
MIRT552781 YIPF6 Yip1 domain family member 6 2 2
MIRT553742 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 4
MIRT553909 SUMO2 small ubiquitin-like modifier 2 2 2
MIRT554540 RRS1 ribosome biogenesis regulator homolog 2 2
MIRT555319 PPP2CB protein phosphatase 2 catalytic subunit beta 2 2
MIRT555512 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT556221 MB21D2 Mab-21 domain containing 2 2 2
MIRT556292 MAP3K5 mitogen-activated protein kinase kinase kinase 5 2 2
MIRT556606 LDOC1L retrotransposon Gag like 6 2 4
MIRT556901 ISOC1 isochorismatase domain containing 1 2 2
MIRT557675 GATA6 GATA binding protein 6 2 2
MIRT560198 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT560493 BUB3 BUB3, mitotic checkpoint protein 2 2
MIRT566069 RCC2 regulator of chromosome condensation 2 2 2
MIRT568431 GDNF glial cell derived neurotrophic factor 2 2
MIRT570703 FAM69A family with sequence similarity 69 member A 2 2
MIRT571705 RPL36A-HNRNPH2 RPL36A-HNRNPH2 readthrough 2 2
MIRT573152 ITGA9 integrin subunit alpha 9 2 2
MIRT574410 TFAP2A transcription factor AP-2 alpha 2 2
MIRT614823 PVRL4 nectin cell adhesion molecule 4 2 2
MIRT616507 COX7A2L cytochrome c oxidase subunit 7A2 like 2 2
MIRT618301 COL4A4 collagen type IV alpha 4 chain 2 2
MIRT621188 FAM153B family with sequence similarity 153 member B 2 2
MIRT621594 WT1 Wilms tumor 1 2 2
MIRT623814 GGCX gamma-glutamyl carboxylase 2 2
MIRT624407 CCDC171 coiled-coil domain containing 171 2 2
MIRT625136 CKAP2L cytoskeleton associated protein 2 like 2 2
MIRT626121 MRRF mitochondrial ribosome recycling factor 2 2
MIRT626874 AP3B1 adaptor related protein complex 3 beta 1 subunit 2 2
MIRT627874 PAN2 PAN2 poly(A) specific ribonuclease subunit 2 2
MIRT633670 FAM53B family with sequence similarity 53 member B 2 2
MIRT634285 SYAP1 synapse associated protein 1 2 2
MIRT640925 POU2F1 POU class 2 homeobox 1 2 2
MIRT642028 MYADM myeloid associated differentiation marker 2 2
MIRT643031 CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 2 2
MIRT646122 SLC26A9 solute carrier family 26 member 9 2 2
MIRT646245 SNAP47 synaptosome associated protein 47 2 2
MIRT652457 TMEM2 transmembrane protein 2 2 2
MIRT657018 KCNK5 potassium two pore domain channel subfamily K member 5 2 2
MIRT660586 APP amyloid beta precursor protein 2 2
MIRT664316 CD209 CD209 molecule 2 2
MIRT667113 OLA1 Obg like ATPase 1 2 2
MIRT668773 DCP2 decapping mRNA 2 2 2
MIRT698430 TM4SF1 transmembrane 4 L six family member 1 2 2
MIRT700216 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT710498 CAPRIN1 cell cycle associated protein 1 2 2
MIRT711836 AMOTL2 angiomotin like 2 2 2
MIRT713226 GPR75 G protein-coupled receptor 75 2 2
MIRT714415 TBC1D16 TBC1 domain family member 16 2 2
MIRT714490 HSPA4 heat shock protein family A (Hsp70) member 4 2 2
MIRT715254 F9 coagulation factor IX 2 2
MIRT716250 PALM2 paralemmin 2 2 2
MIRT717261 BMPR2 bone morphogenetic protein receptor type 2 2 2
MIRT717730 FGF1 fibroblast growth factor 1 2 2
MIRT719262 CD44 CD44 molecule (Indian blood group) 2 2
MIRT719398 SLC15A4 solute carrier family 15 member 4 2 2
MIRT720653 TMEM218 transmembrane protein 218 2 2
MIRT720777 MSANTD3-TMEFF1 MSANTD3-TMEFF1 readthrough 2 2
MIRT722059 TMEFF1 transmembrane protein with EGF like and two follistatin like domains 1 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-302b Epirubicin approved 41867 Microarray osteosarcoma cells 23845851 2013 down-regualted
miR-302b Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-302b 1,2,6-Tri-O-galloyl-beta-D-glucopyranose NULL NULL Microarray HepG2 hepatocarcinoma cells. 22506400 2011 up-regulated
miR-302b 1,2,6-Tri-O-galloyl-beta-D-glucopyranose NULL NULL Microarray HepG2 hepatocarcinoma cells. 22506400 2011 down-regulated
miR-302b (S)-3,5-dihydroxyphenylglycine (DHPG) NULL 443586 Quantitative real-time PCR mouse brain 22309833 2012 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-302b Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)
hsa-miR-302b-5p Paclitaxel 36314 NSC125973 approved sensitive High Laryngeal Cancer cell line (Hep2)
hsa-miR-302b-5p Celastrol 12302620 NSC70931 sensitive Low Gastric Cancer cell line (AGS)
hsa-miR-302b-5p Docetaxel 148124 NSC628503 approved sensitive Low Gastric Cancer cell line (AGS)
hsa-miR-302b-5p Doxorubicin 31703 NSC123127 approved sensitive Low Gastric Cancer cell line (AGS)
hsa-miR-302b-5p Taxol 36314 NSC125973 approved sensitive Low Gastric Cancer cell line (AGS)
hsa-miR-302b-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-302b-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-302b-5p Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-miR-302b-5p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-302b-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-302b-5p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide sensitive cell line (Bads-200)

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