miRTarBase - #MIRT220130


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pre-miRNA Information
pre-miRNA hsa-mir-4796   
Genomic Coordinates chr3: 114743445 - 114743525
Description Homo sapiens miR-4796 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4796-3p
Sequence 53| UAAAGUGGCAGAGUAUAGACAC |74
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN9734363 9 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1045223845 8 dbSNP
rs185555286 18 dbSNP
Putative Targets

Gene Information
Gene Symbol CAV1   
Synonyms BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21
Description caveolin 1
Transcript NM_001172895   
Other Transcripts NM_001172896 , NM_001172897 , NM_001753   
Expression
Putative miRNA Targets on CAV1
3'UTR of CAV1
(miRNA target sites are highlighted)		 
>CAV1|NM_001172895|3'UTR
   1 ATGACATTTCAAGGATAGAAGTATACCTGATTTTTTTTCCTTTTAATTTTCCTGGTGCCAATTTCAAGTTCCAAGTTGCT
  81 AATACAGCAACAATTTATGAATTGAATTATCTTGGTTGAAAATAAAAAGATCACTTTCTCAGTTTTCATAAGTATTATGT
 161 CTCTTCTGAGCTATTTCATCTATTTTTGGCAGTCTGAATTTTTAAAACCCATTTAAATTTTTTTCCTTACCTTTTTATTT
 241 GCATGTGGATCAACCATCGCTTTATTGGCTGAGATATGAACATATTGTTGAAAGGTAATTTGAGAGAAATATGAAGAACT
 321 GAGGAGGAAAAAAAAAAAAAAGAAAAGAACCAACAACCTCAACTGCCTACTCCAAAATGTTGGTCATTTTATGTTAAGGG
 401 AAGAATTCCAGGGTATGGCCATGGAGTGTACAAGTATGTGGGCAGATTTTCAGCAAACTCTTTTCCCACTGTTTAAGGAG
 481 TTAGTGGATTACTGCCATTCACTTCATAATCCAGTAGGATCCAGTGATCCTTACAAGTTAGAAAACATAATCTTCTGCCT
 561 TCTCATGATCCAACTAATGCCTTACTCTTCTTGAAATTTTAACCTATGATATTTTCTGTGCCTGAATATTTGTTATGTAG
 641 ATAACAAGACCTCAGTGCCTTCCTGTTTTTCACATTTTCCTTTTCAAATAGGGTCTAACTCAGCAACTCGCTTTAGGTCA
 721 GCAGCCTCCCTGAAGACCAAAATTAGAATATCCATGACCTAGTTTTCCATGCGTGTTTCTGACTCTGAGCTACAGAGTCT
 801 GGTGAAGCTCACTTCTGGGCTTCATCTGGCAACATCTTTATCCGTAGTGGGTATGGTTGACACTAGCCCAATGAAATGAA
 881 TTAAAGTGGACCAATAGGGCTGAGCTCTCTGTGGGCTGGCAGTCCTGGAAGCCAGCTTTCCCTGCCTCTCATCAACTGAA
 961 TGAGGTCAGCATGTCTATTCAGCTTCGTTTATTTTCAAGAATAATCACGCTTTCCTGAATCCAAACTAATCCATCACCGG
1041 GGTGGTTTAGTGGCTCAACATTGTGTTCCCATTTCAGCTGATCAGTGGGCCTCCAAGGAGGGGCTGTAAAATGGAGGCCA
1121 TTGTGTGAGCCTATCAGAGTTGCTGCAAACCTGACCCCTGCTCAGTAAAGCACTTGCAACCGTCTGTTATGCTGTGACAC
1201 ATGGCCCCTCCCCCTGCCAGGAGCTTTGGACCTAATCCAAGCATCCCTTTGCCCAGAAAGAAGATGGGGGAGGAGGCAGT
1281 AATAAAAAGATTGAAGTATTTTGCTGGAATAAGTTCAAATTCTTCTGAACTCAAACTGAGGAATTTCACCTGTAAACCTG
1361 AGTCGTACAGAAAGCTGCCTGGTATATCCAAAAGCTTTTTATTCCTCCTGCTCATATTGTGATTCTGCCTTTGGGGACTT
1441 TTCTTAAACCTTCAGTTATGATTTTTTTTTCATACACTTATTGGAACTCTGCTTGATTTTTGCCTCTTCCAGTCTTCCTG
1521 ACACTTTAATTACCAACCTGTTACCTACTTTGACTTTTTGCATTTAAAACAGACACTGGCATGGATATAGTTTTACTTTT
1601 AAACTGTGTACATAACTGAAAATGTGCTATACTGCATACTTTTTAAATGTAAAGATATTTTTATCTTTATATGAAGAAAA
1681 TCACTTAGGAAATGGCTTTGTGATTCAATCTGTAAACTGTGTATTCCAAGACATGTCTGTTCTACATAGATGCTTAGTCC
1761 CTCATGCAAATCAATTACTGGTCCAAAAGATTGCTGAAATTTTATATGCTTACTGATATATTTTACAATTTTTTATCATG
1841 CATGTCCTGTAAAGGTTACAAGCCTGCACAATAAAAATGTTTAACGGTTAAACAGTCAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' caCAGAUAUGAGAC----GGUGAAAu 5'
            ||||| |||| |    :|:|||| 
Target 5' ggGTCTA-ACTCAGCAACTCGCTTTa 3'
 691 - 715 133.00 -15.20
2 
miRNA  3' cacAGAU--AUG---AGAC----GGUGAAAu 5'
             |:||  |||    |||    |:||||| 
Target 5' cacTTTAATTACCAACCTGTTACCTACTTTg 3'
 1522 - 1552 131.00 -8.20
3 
miRNA  3' caCAGAUAUGAGACGGUGAAAu 5'
            ||||   : ||| |||||| 
Target 5' caGTCT---TCCTGACACTTTa 3'
 1510 - 1528 129.00 -14.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1185915 328 ClinVar
COSN30495938 21 COSMIC
COSN32053247 30 COSMIC
COSN31574840 33 COSMIC
COSN30101344 40 COSMIC
COSN9823063 59 COSMIC
COSN30124225 61 COSMIC
COSN30542418 76 COSMIC
COSN31480381 181 COSMIC
COSN31545436 330 COSMIC
COSN16670109 338 COSMIC
COSN27239952 342 COSMIC
COSN26504748 343 COSMIC
COSN31521776 433 COSMIC
COSN26550782 441 COSMIC
COSN31571644 465 COSMIC
COSN31591299 580 COSMIC
COSN31571661 617 COSMIC
COSN15400017 738 COSMIC
COSN31522138 827 COSMIC
COSN22271590 844 COSMIC
COSN31960041 845 COSMIC
COSN25045646 889 COSMIC
COSN146841 937 COSMIC
COSN25463948 988 COSMIC
COSN17131917 1062 COSMIC
COSN15834460 1098 COSMIC
COSN7651595 1353 COSMIC
COSN5811722 1366 COSMIC
COSN20933438 1525 COSMIC
COSN31592940 1556 COSMIC
COSN31482554 1593 COSMIC
COSN28677595 1677 COSMIC
COSN31544340 1690 COSMIC
COSN26556854 1753 COSMIC
COSN31535840 1784 COSMIC
COSN19658976 1789 COSMIC
COSN31485536 1802 COSMIC
COSN31594256 1809 COSMIC
COSN31609762 1830 COSMIC
COSN9920368 1850 COSMIC
rs9920 752 GWAS
rs1049334 1040 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs761716987 1 dbSNP
rs1394696314 6 dbSNP
rs767326115 12 dbSNP
rs1160595550 13 dbSNP
rs1204917918 13 dbSNP
rs1485315515 16 dbSNP
rs1386160027 17 dbSNP
rs1265879354 19 dbSNP
rs750440706 21 dbSNP
rs1316812058 23 dbSNP
rs959737965 27 dbSNP
rs770728673 28 dbSNP
rs759347653 31 dbSNP
rs776370468 31 dbSNP
rs766386022 36 dbSNP
rs1381465797 39 dbSNP
rs1437718225 39 dbSNP
rs1202870251 40 dbSNP
rs1248763701 41 dbSNP
rs1489002857 46 dbSNP
rs1193944886 47 dbSNP
rs528806115 48 dbSNP
rs1022683249 57 dbSNP
rs1458029243 79 dbSNP
rs969766633 82 dbSNP
rs1405419736 86 dbSNP
rs543002723 93 dbSNP
rs1467966847 96 dbSNP
rs947666583 100 dbSNP
rs1048721600 103 dbSNP
rs565499793 131 dbSNP
rs1190105760 132 dbSNP
rs532717248 135 dbSNP
rs1201906339 138 dbSNP
rs1015158708 149 dbSNP
rs1256498817 153 dbSNP
rs768207509 153 dbSNP
rs1226658948 156 dbSNP
rs950851695 157 dbSNP
rs10237996 167 dbSNP
rs550437121 168 dbSNP
rs41309216 169 dbSNP
rs1382312196 171 dbSNP
rs1029669016 178 dbSNP
rs568923511 179 dbSNP
rs1403064437 182 dbSNP
rs1180162585 210 dbSNP
rs985862700 218 dbSNP
rs944736953 219 dbSNP
rs1169631774 220 dbSNP
rs1477274522 226 dbSNP
rs1172492795 227 dbSNP
rs1426570189 230 dbSNP
rs1416660986 231 dbSNP
rs1168342084 232 dbSNP
rs1185030321 242 dbSNP
rs1039431325 244 dbSNP
rs571670408 246 dbSNP
rs968694006 250 dbSNP
rs529701284 251 dbSNP
rs547782440 255 dbSNP
rs978392621 259 dbSNP
rs1276425318 260 dbSNP
rs1228902943 272 dbSNP
rs566090149 275 dbSNP
rs533848832 284 dbSNP
rs924208369 286 dbSNP
rs946779460 287 dbSNP
rs1341135396 296 dbSNP
rs867368056 303 dbSNP
rs558410705 305 dbSNP
rs1408466406 308 dbSNP
rs1372981610 321 dbSNP
rs1424400404 326 dbSNP
rs36068092 326 dbSNP
rs62469032 327 dbSNP
rs201948319 328 dbSNP
rs543686960 328 dbSNP
rs71528103 328 dbSNP
rs34123906 329 dbSNP
rs1346948808 330 dbSNP
rs1212747156 332 dbSNP
rs1482008054 333 dbSNP
rs1253911649 335 dbSNP
rs939469109 338 dbSNP
rs1490115976 342 dbSNP
rs201088440 343 dbSNP
rs1200119628 348 dbSNP
rs1042943107 354 dbSNP
rs1049314 355 dbSNP
rs1357327934 356 dbSNP
rs916291733 357 dbSNP
rs1198519383 358 dbSNP
rs1352460255 359 dbSNP
rs999057379 371 dbSNP
rs1049196046 373 dbSNP
rs112960381 379 dbSNP
rs895696091 380 dbSNP
rs1013950727 399 dbSNP
rs1422968980 400 dbSNP
rs1466251449 419 dbSNP
rs1391040042 422 dbSNP
rs1157428623 423 dbSNP
rs770660896 424 dbSNP
rs145339317 427 dbSNP
rs969820465 435 dbSNP
rs901776413 442 dbSNP
rs575697009 446 dbSNP
rs1244704810 454 dbSNP
rs8713 457 dbSNP
rs1332645545 461 dbSNP
rs1428520444 462 dbSNP
rs1283800891 465 dbSNP
rs1207104970 481 dbSNP
rs889861195 486 dbSNP
rs751496769 489 dbSNP
rs1223374720 493 dbSNP
rs1220012412 499 dbSNP
rs1007005977 504 dbSNP
rs1437653445 509 dbSNP
rs1022702043 517 dbSNP
rs1319430171 519 dbSNP
rs878866269 522 dbSNP
rs1455376036 525 dbSNP
rs1390186821 530 dbSNP
rs983996088 542 dbSNP
rs912172840 566 dbSNP
rs190869026 567 dbSNP
rs1478215973 569 dbSNP
rs767507664 571 dbSNP
rs11553391 580 dbSNP
rs573244957 581 dbSNP
rs1192098115 604 dbSNP
rs565604311 608 dbSNP
rs1478185276 609 dbSNP
rs960949225 610 dbSNP
rs757360963 622 dbSNP
rs979516188 659 dbSNP
rs765415898 662 dbSNP
rs1366808176 663 dbSNP
rs992322396 667 dbSNP
rs934526384 668 dbSNP
rs878999727 675 dbSNP
rs1053349384 684 dbSNP
rs1164094963 693 dbSNP
rs916781925 694 dbSNP
rs1446626657 710 dbSNP
rs766860458 711 dbSNP
rs1356971916 728 dbSNP
rs1178135549 730 dbSNP
rs1415032738 733 dbSNP
rs540955207 740 dbSNP
rs969531166 742 dbSNP
rs895757811 743 dbSNP
rs565562402 744 dbSNP
rs9920 752 dbSNP
rs180751055 764 dbSNP
rs780349420 765 dbSNP
rs35901258 767 dbSNP
rs375427517 770 dbSNP
rs1211423117 771 dbSNP
rs886175009 773 dbSNP
rs185904779 774 dbSNP
rs1339396901 776 dbSNP
rs747404134 796 dbSNP
rs1297839957 802 dbSNP
rs529802934 804 dbSNP
rs1227456429 806 dbSNP
rs1376331269 808 dbSNP
rs933273449 812 dbSNP
rs1050205017 825 dbSNP
rs1448587371 827 dbSNP
rs1369913866 832 dbSNP
rs1305896097 833 dbSNP
rs888974362 837 dbSNP
rs1019525896 838 dbSNP
rs966351866 841 dbSNP
rs1164335147 843 dbSNP
rs1011845915 844 dbSNP
rs149177372 845 dbSNP
rs1029211305 850 dbSNP
rs35386406 858 dbSNP
rs999491517 872 dbSNP
rs1285756080 883 dbSNP
rs527278612 889 dbSNP
rs1291582975 894 dbSNP
rs960937810 898 dbSNP
rs1319560268 912 dbSNP
rs1314202511 922 dbSNP
rs1228422391 927 dbSNP
rs924080469 936 dbSNP
rs1013873385 941 dbSNP
rs1254137811 947 dbSNP
rs1441969850 949 dbSNP
rs1188494690 965 dbSNP
rs935395392 973 dbSNP
rs1023790764 977 dbSNP
rs1438073401 978 dbSNP
rs1157768517 979 dbSNP
rs1370921034 987 dbSNP
rs145054697 988 dbSNP
rs570724286 998 dbSNP
rs949874976 1000 dbSNP
rs781732927 1005 dbSNP
rs146803992 1010 dbSNP
rs140524634 1028 dbSNP
rs747569840 1033 dbSNP
rs1409936468 1035 dbSNP
rs769465615 1038 dbSNP
rs145622599 1039 dbSNP
rs1049334 1040 dbSNP
rs1335775007 1043 dbSNP
rs555077303 1046 dbSNP
rs1005030680 1052 dbSNP
rs1018661556 1053 dbSNP
rs1265756202 1057 dbSNP
rs1230090951 1062 dbSNP
rs1351036232 1063 dbSNP
rs1043282251 1066 dbSNP
rs1384883704 1069 dbSNP
rs902013118 1079 dbSNP
rs1308917788 1081 dbSNP
rs573308190 1091 dbSNP
rs1386473365 1094 dbSNP
rs1242928121 1117 dbSNP
rs903931514 1118 dbSNP
rs996324095 1130 dbSNP
rs1482965977 1142 dbSNP
rs1029263657 1149 dbSNP
rs1174639728 1150 dbSNP
rs968279292 1152 dbSNP
rs979452226 1156 dbSNP
rs935446169 1160 dbSNP
rs1258368708 1166 dbSNP
rs1464169276 1171 dbSNP
rs1052421551 1175 dbSNP
rs1210085978 1177 dbSNP
rs879910828 1181 dbSNP
rs11553395 1182 dbSNP
rs6867 1183 dbSNP
rs1231065782 1185 dbSNP
rs577466219 1187 dbSNP
rs917983722 1190 dbSNP
rs1301738369 1196 dbSNP
rs1023864454 1199 dbSNP
rs34709923 1201 dbSNP
rs1322586971 1203 dbSNP
rs1173853078 1208 dbSNP
rs1006386869 1209 dbSNP
rs146148467 1210 dbSNP
rs1377066633 1213 dbSNP
rs374946197 1214 dbSNP
rs574904812 1226 dbSNP
rs927237257 1232 dbSNP
rs1168355475 1236 dbSNP
rs930556591 1238 dbSNP
rs541560458 1245 dbSNP
rs1049337 1247 dbSNP
rs527335291 1248 dbSNP
rs954350548 1255 dbSNP
rs1254944328 1265 dbSNP
rs985770825 1266 dbSNP
rs910429010 1269 dbSNP
rs947328803 1270 dbSNP
rs183233509 1272 dbSNP
rs1393573200 1278 dbSNP
rs759401731 1282 dbSNP
rs940328551 1292 dbSNP
rs1040547402 1293 dbSNP
rs1300060484 1298 dbSNP
rs1299654306 1310 dbSNP
rs1339928619 1311 dbSNP
rs140386119 1326 dbSNP
rs1398231564 1336 dbSNP
rs996377834 1350 dbSNP
rs1403578420 1355 dbSNP
rs563887249 1365 dbSNP
rs531651322 1366 dbSNP
rs1001110476 1372 dbSNP
rs1198223832 1376 dbSNP
rs1170081652 1379 dbSNP
rs35273517 1385 dbSNP
rs1367312009 1390 dbSNP
rs761861572 1405 dbSNP
rs1458922846 1406 dbSNP
rs11553390 1408 dbSNP
rs1425439011 1413 dbSNP
rs956938598 1414 dbSNP
rs1481945852 1417 dbSNP
rs1276577256 1418 dbSNP
rs1013557873 1419 dbSNP
rs1355915185 1428 dbSNP
rs1266420858 1432 dbSNP
rs1247111286 1433 dbSNP
rs1025508301 1435 dbSNP
rs969427195 1442 dbSNP
rs1408599334 1445 dbSNP
rs1420791246 1446 dbSNP
rs1006914787 1462 dbSNP
rs1016416065 1462 dbSNP
rs897966902 1471 dbSNP
rs993642038 1478 dbSNP
rs568272855 1482 dbSNP
rs1458969676 1490 dbSNP
rs551371884 1493 dbSNP
rs1401946933 1497 dbSNP
rs927119618 1498 dbSNP
rs1471574958 1502 dbSNP
rs1253618679 1503 dbSNP
rs1182293337 1514 dbSNP
rs750639875 1521 dbSNP
rs1292100536 1533 dbSNP
rs954467194 1538 dbSNP
rs1287963134 1545 dbSNP
rs1367386224 1552 dbSNP
rs1211898623 1553 dbSNP
rs951846773 1554 dbSNP
rs1335542087 1555 dbSNP
rs1049375 1560 dbSNP
rs35617054 1561 dbSNP
rs1227025294 1571 dbSNP
rs1352900160 1574 dbSNP
rs1285804031 1581 dbSNP
rs1280456542 1582 dbSNP
rs553664696 1583 dbSNP
rs985754778 1589 dbSNP
rs34585220 1596 dbSNP
rs907762826 1604 dbSNP
rs1442718527 1606 dbSNP
rs979109070 1608 dbSNP
rs1157774023 1612 dbSNP
rs1455538249 1613 dbSNP
rs1482950004 1618 dbSNP
rs1159124134 1619 dbSNP
rs1477555969 1619 dbSNP
rs1244831371 1625 dbSNP
rs924569077 1626 dbSNP
rs1469079200 1632 dbSNP
rs934451100 1638 dbSNP
rs1206930278 1650 dbSNP
rs542937271 1651 dbSNP
rs1309421935 1655 dbSNP
rs1285540883 1656 dbSNP
rs1219232575 1665 dbSNP
rs1343302015 1680 dbSNP
rs1276982649 1681 dbSNP
rs6868 1684 dbSNP
rs1442563397 1686 dbSNP
rs992668412 1691 dbSNP
rs757217243 1694 dbSNP
rs534236443 1703 dbSNP
rs917967683 1708 dbSNP
rs1219668208 1709 dbSNP
rs796502851 1710 dbSNP
rs374969893 1713 dbSNP
rs1211555591 1714 dbSNP
rs1422714603 1715 dbSNP
rs1261029664 1718 dbSNP
rs778726620 1719 dbSNP
rs1454837776 1734 dbSNP
rs1389761257 1736 dbSNP
rs1477459931 1738 dbSNP
rs931717546 1743 dbSNP
rs1193689218 1747 dbSNP
rs1050618231 1750 dbSNP
rs1045060352 1752 dbSNP
rs369427253 1754 dbSNP
rs1421648457 1756 dbSNP
rs1000996401 1757 dbSNP
rs1053129173 1766 dbSNP
rs1235505773 1767 dbSNP
rs1038332070 1768 dbSNP
rs1349641582 1781 dbSNP
rs892705378 1789 dbSNP
rs1296375935 1791 dbSNP
rs993589427 1793 dbSNP
rs1458787070 1801 dbSNP
rs1270277207 1802 dbSNP
rs577127115 1807 dbSNP
rs1014027835 1813 dbSNP
rs1024973120 1814 dbSNP
rs1051922020 1817 dbSNP
rs890194110 1820 dbSNP
rs1007291671 1829 dbSNP
rs969476489 1831 dbSNP
rs538550256 1838 dbSNP
rs556565826 1845 dbSNP
rs1181381738 1860 dbSNP
rs1364206166 1863 dbSNP
rs574733654 1864 dbSNP
rs542018638 1867 dbSNP
rs34397467 1870 dbSNP
rs1312336101 1877 dbSNP
rs951898689 1886 dbSNP
rs560268745 1887 dbSNP
rs187498039 1888 dbSNP
rs1308925310 1890 dbSNP
rs917116576 1891 dbSNP
rs1283644450 1898 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cacAGAU--AUG---AGAC----GGUGAAAu 5'
             |:||  |||    |||    |:||||| 
Target 5' cacUUUAAUUACCAACCUGUUACCUACUUUg 3'
 		10 - 40
2 
miRNA  3' cacAGAUAUGAGACGGUGAAAu 5'
             |||   : ||| |||||| 
Target 5' ---UCU---UCCUGACACUUUa 3'
 		1 - 16
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000405348.1 | 3UTR | UCUUCCUGACACUUUAAUUACCAACCUGUUACCUACUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
276 hsa-miR-4796-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057030 SGPL1 sphingosine-1-phosphate lyase 1 2 2
MIRT065682 ACVR1B activin A receptor type 1B 2 6
MIRT066973 ATXN7L3B ataxin 7 like 3B 2 2
MIRT068903 TPRG1L tumor protein p63 regulated 1 like 2 2
MIRT069713 FOXJ3 forkhead box J3 2 2
MIRT072259 B2M beta-2-microglobulin 2 10
MIRT074331 TNRC6A trinucleotide repeat containing 6A 2 10
MIRT075132 C16ORF70 chromosome 16 open reading frame 70 2 4
MIRT077079 KRT10 keratin 10 2 8
MIRT084604 BCL2L11 BCL2 like 11 2 8
MIRT088056 UBXN2A UBX domain protein 2A 2 4
MIRT103212 SP4 Sp4 transcription factor 2 6
MIRT108733 XIAP X-linked inhibitor of apoptosis 2 2
MIRT135263 TMBIM6 transmembrane BAX inhibitor motif containing 6 2 8
MIRT140170 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT173042 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT182530 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT184890 ULK1 unc-51 like autophagy activating kinase 1 2 2
MIRT187490 PCBP2 poly(rC) binding protein 2 2 4
MIRT188195 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT190442 EIF5 eukaryotic translation initiation factor 5 2 2
MIRT201089 ZNF805 zinc finger protein 805 2 2
MIRT213239 REST RE1 silencing transcription factor 2 2
MIRT213335 KIAA0232 KIAA0232 2 2
MIRT220130 CAV1 caveolin 1 2 2
MIRT257298 FOXC1 forkhead box C1 2 2
MIRT260352 XRCC6 X-ray repair cross complementing 6 2 6
MIRT262478 KLF6 Kruppel like factor 6 2 2
MIRT263459 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT291952 TPM4 tropomyosin 4 2 2
MIRT295277 LZIC leucine zipper and CTNNBIP1 domain containing 2 4
MIRT300679 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT322414 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT338103 CLIC4 chloride intracellular channel 4 2 4
MIRT361507 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT365827 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT371746 ATXN1 ataxin 1 2 2
MIRT375470 NFAT5 nuclear factor of activated T-cells 5 2 6
MIRT387879 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 6
MIRT395213 PRKCB protein kinase C beta 2 2
MIRT407418 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT442641 TBC1D12 TBC1 domain family member 12 2 2
MIRT442757 NRIP3 nuclear receptor interacting protein 3 2 2
MIRT443435 MAPT microtubule associated protein tau 2 2
MIRT443707 LLPH LLP homolog, long-term synaptic facilitation 2 2
MIRT444306 SREK1IP1 SREK1 interacting protein 1 2 2
MIRT447332 SSU72 SSU72 homolog, RNA polymerase II CTD phosphatase 2 2
MIRT448310 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT448362 TSR1 TSR1, ribosome maturation factor 2 6
MIRT448388 TP53INP1 tumor protein p53 inducible nuclear protein 1 2 2
MIRT448640 NPNT nephronectin 2 2
MIRT450184 TMEM9B TMEM9 domain family member B 2 2
MIRT452303 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT453732 RAP1GDS1 Rap1 GTPase-GDP dissociation stimulator 1 2 2
MIRT455237 KIAA2013 KIAA2013 2 2
MIRT456354 CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 2 2
MIRT457591 NCOA3 nuclear receptor coactivator 3 2 2
MIRT458288 FUT10 fucosyltransferase 10 2 2
MIRT458694 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT462073 CCDC77 coiled-coil domain containing 77 2 2
MIRT462122 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT463267 ZFYVE9 zinc finger FYVE-type containing 9 2 2
MIRT465103 TSC22D3 TSC22 domain family member 3 2 4
MIRT465108 TSC22D2 TSC22 domain family member 2 2 4
MIRT465228 TRIP10 thyroid hormone receptor interactor 10 2 2
MIRT465830 TMEM64 transmembrane protein 64 2 2
MIRT466450 TFAM transcription factor A, mitochondrial 2 8
MIRT467464 SNAPIN SNAP associated protein 2 2
MIRT467490 SMIM13 small integral membrane protein 13 2 6
MIRT467890 SLC22A23 solute carrier family 22 member 23 2 2
MIRT468846 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT469699 RAB5B RAB5B, member RAS oncogene family 2 8
MIRT469853 PXK PX domain containing serine/threonine kinase like 2 8
MIRT470265 PRR14L proline rich 14 like 2 2
MIRT471136 PHF19 PHD finger protein 19 2 2
MIRT471265 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT471917 NSUN4 NOP2/Sun RNA methyltransferase family member 4 2 2
MIRT472051 NPAT nuclear protein, coactivator of histone transcription 2 2
MIRT472161 NIN ninein 2 4
MIRT472339 NETO2 neuropilin and tolloid like 2 2 4
MIRT473262 MIDN midnolin 2 10
MIRT473326 MEX3A mex-3 RNA binding family member A 2 2
MIRT474868 KDM5B lysine demethylase 5B 2 2
MIRT475050 JOSD1 Josephin domain containing 1 2 2
MIRT475467 HSPA8 heat shock protein family A (Hsp70) member 8 2 6
MIRT475695 HHIPL1 HHIP like 1 2 2
MIRT476905 FBXL5 F-box and leucine rich repeat protein 5 2 12
MIRT477187 F3 coagulation factor III, tissue factor 2 8
MIRT477281 ERGIC2 ERGIC and golgi 2 2 2
MIRT478551 CTNND1 catenin delta 1 2 2
MIRT479035 COIL coilin 2 10
MIRT479059 CNOT6L CCR4-NOT transcription complex subunit 6 like 2 8
MIRT479263 CHSY1 chondroitin sulfate synthase 1 2 2
MIRT479801 CCND1 cyclin D1 2 12
MIRT479847 CCDC86 coiled-coil domain containing 86 2 2
MIRT480522 C11orf30 EMSY, BRCA2 interacting transcriptional repressor 2 10
MIRT480556 BZW1 basic leucine zipper and W2 domains 1 2 2
MIRT481340 ATL3 atlastin GTPase 3 2 2
MIRT481960 ANKH ANKH inorganic pyrophosphate transport regulator 2 8
MIRT482135 AKAP11 A-kinase anchoring protein 11 2 12
MIRT482474 ADAR adenosine deaminase, RNA specific 2 4
MIRT484824 ZNFX1 zinc finger NFX1-type containing 1 2 2
MIRT484911 ZFYVE26 zinc finger FYVE-type containing 26 2 4
MIRT485188 PTP4A1 protein tyrosine phosphatase type IVA, member 1 2 4
MIRT485366 MYLIP myosin regulatory light chain interacting protein 2 12
MIRT488821 TBC1D28 TBC1 domain family member 28 2 2
MIRT491802 ZFYVE21 zinc finger FYVE-type containing 21 2 8
MIRT492006 UGCG UDP-glucose ceramide glucosyltransferase 2 2
MIRT492365 SEMA7A semaphorin 7A (John Milton Hagen blood group) 2 2
MIRT493389 KIAA0513 KIAA0513 2 6
MIRT493667 HBP1 HMG-box transcription factor 1 2 2
MIRT494068 DUSP2 dual specificity phosphatase 2 2 4
MIRT494384 SOLH calpain 15 2 2
MIRT494426 BTG2 BTG anti-proliferation factor 2 2 4
MIRT494775 ANKRD33B ankyrin repeat domain 33B 2 10
MIRT498159 FEM1C fem-1 homolog C 2 8
MIRT499904 KIAA1191 KIAA1191 2 4
MIRT500763 TMEM127 transmembrane protein 127 2 6
MIRT501460 PTPN4 protein tyrosine phosphatase, non-receptor type 4 2 8
MIRT501955 MAPRE3 microtubule associated protein RP/EB family member 3 2 8
MIRT502367 GIGYF1 GRB10 interacting GYF protein 1 2 8
MIRT502400 GATA6 GATA binding protein 6 2 8
MIRT503444 GINS4 GINS complex subunit 4 2 4
MIRT503605 ZNF780A zinc finger protein 780A 2 2
MIRT503824 TMEM242 transmembrane protein 242 2 4
MIRT504095 C9orf40 chromosome 9 open reading frame 40 2 6
MIRT505278 TUBB2A tubulin beta 2A class IIa 2 2
MIRT505489 SRSF2 serine and arginine rich splicing factor 2 2 4
MIRT505740 SEPT2 septin 2 2 4
MIRT505976 RAB11FIP1 RAB11 family interacting protein 1 2 4
MIRT506228 PFKP phosphofructokinase, platelet 2 8
MIRT506431 NAGK N-acetylglucosamine kinase 2 6
MIRT506454 NACC2 NACC family member 2 2 4
MIRT506617 MARCH6 membrane associated ring-CH-type finger 6 2 8
MIRT506838 KIF23 kinesin family member 23 2 4
MIRT506865 KIAA1147 KIAA1147 2 2
MIRT507189 FZD9 frizzled class receptor 9 2 6
MIRT507235 FOXK2 forkhead box K2 2 4
MIRT507362 FAM129A family with sequence similarity 129 member A 2 6
MIRT507942 BTF3L4 basic transcription factor 3 like 4 2 6
MIRT508087 ANKRD52 ankyrin repeat domain 52 2 2
MIRT508134 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT511083 NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 2 4
MIRT511257 KLHL36 kelch like family member 36 2 6
MIRT511610 HIST1H4H histone cluster 1 H4 family member h 2 2
MIRT511725 HIST1H2BF histone cluster 1 H2B family member f 2 2
MIRT512318 ACTR2 ARP2 actin related protein 2 homolog 2 6
MIRT513462 NARS asparaginyl-tRNA synthetase 2 6
MIRT513984 CEP97 centrosomal protein 97 2 2
MIRT513998 CENPQ centromere protein Q 2 4
MIRT514035 BNIP2 BCL2 interacting protein 2 2 2
MIRT514096 EPS15L1 epidermal growth factor receptor pathway substrate 15 like 1 2 6
MIRT514993 DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 2 2
MIRT517016 COX19 COX19, cytochrome c oxidase assembly factor 2 2
MIRT524699 BTG3 BTG anti-proliferation factor 3 2 8
MIRT525199 ZNF93 zinc finger protein 93 2 2
MIRT527200 XIRP2 xin actin binding repeat containing 2 2 2
MIRT527469 CLEC12B C-type lectin domain family 12 member B 2 4
MIRT527888 SERF1B small EDRK-rich factor 1B 2 2
MIRT529344 SERF1A small EDRK-rich factor 1A 2 2
MIRT529493 TPD52L3 tumor protein D52 like 3 2 2
MIRT531821 ZNF264 zinc finger protein 264 2 6
MIRT531835 MTPAP mitochondrial poly(A) polymerase 2 4
MIRT532509 KCNN1 potassium calcium-activated channel subfamily N member 1 2 2
MIRT533390 U2SURP U2 snRNP associated SURP domain containing 2 6
MIRT533836 TGFBR2 transforming growth factor beta receptor 2 2 6
MIRT533876 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT534005 SUV420H1 lysine methyltransferase 5B 2 2
MIRT534626 RNASEH1 ribonuclease H1 2 4
MIRT537731 ELAVL2 ELAV like RNA binding protein 2 2 2
MIRT537781 EIF4H eukaryotic translation initiation factor 4H 2 6
MIRT538716 CAPRIN2 caprin family member 2 2 4
MIRT541088 RLIM ring finger protein, LIM domain interacting 2 2
MIRT541284 GLO1 glyoxalase I 2 2
MIRT542058 SLC25A46 solute carrier family 25 member 46 2 2
MIRT542952 GDF11 growth differentiation factor 11 2 2
MIRT543506 PLS1 plastin 1 2 2
MIRT543578 RPF2 ribosome production factor 2 homolog 2 4
MIRT545201 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT546254 TNFRSF21 TNF receptor superfamily member 21 2 2
MIRT546293 TMEM200C transmembrane protein 200C 2 4
MIRT546457 SLC5A3 solute carrier family 5 member 3 2 4
MIRT546494 SIK1 salt inducible kinase 1 2 2
MIRT546820 RAP2C RAP2C, member of RAS oncogene family 2 2
MIRT547080 PLRG1 pleiotropic regulator 1 2 2
MIRT548228 FJX1 four jointed box 1 2 4
MIRT548338 EPHA4 EPH receptor A4 2 2
MIRT548390 ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 2 4
MIRT548463 EGLN3 egl-9 family hypoxia inducible factor 3 2 2
MIRT548862 CERCAM cerebral endothelial cell adhesion molecule 2 2
MIRT549821 LUZP2 leucine zipper protein 2 2 2
MIRT550092 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT550241 PVR poliovirus receptor 2 4
MIRT551744 FMNL2 formin like 2 2 2
MIRT552203 F2RL3 F2R like thrombin or trypsin receptor 3 2 2
MIRT552639 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT552684 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 4
MIRT553031 USP48 ubiquitin specific peptidase 48 2 2
MIRT553474 TNKS2 tankyrase 2 2 2
MIRT554329 SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 2 2
MIRT554411 SCD stearoyl-CoA desaturase 2 2
MIRT554474 SAMD12 sterile alpha motif domain containing 12 2 2
MIRT554529 RUFY2 RUN and FYVE domain containing 2 2 2
MIRT554554 RRN3 RRN3 homolog, RNA polymerase I transcription factor 2 2
MIRT554611 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT554744 RHOC ras homolog family member C 2 2
MIRT554802 RGMB repulsive guidance molecule family member b 2 4
MIRT555165 PTPDC1 protein tyrosine phosphatase domain containing 1 2 2
MIRT555192 PRUNE2 prune homolog 2 2 2
MIRT556143 MED17 mediator complex subunit 17 2 2
MIRT556591 LEPROT leptin receptor overlapping transcript 2 2
MIRT556903 ISOC1 isochorismatase domain containing 1 2 2
MIRT557756 FRS2 fibroblast growth factor receptor substrate 2 2 2
MIRT557828 FOXJ2 forkhead box J2 2 2
MIRT558220 EFCAB14 EF-hand calcium binding domain 14 2 4
MIRT558331 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT558934 CBX1 chromobox 1 2 2
MIRT559078 C19orf47 chromosome 19 open reading frame 47 2 4
MIRT559439 ARSJ arylsulfatase family member J 2 2
MIRT561376 TXNIP thioredoxin interacting protein 2 2
MIRT561644 RUNX3 runt related transcription factor 3 2 2
MIRT561741 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT562214 HMGB2 high mobility group box 2 2 2
MIRT562558 CCDC71L coiled-coil domain containing 71 like 2 4
MIRT562964 LRPAP1 LDL receptor related protein associated protein 1 2 2
MIRT563378 DSPP dentin sialophosphoprotein 2 2
MIRT566557 OTUD4 OTU deubiquitinase 4 2 2
MIRT566878 LRP12 LDL receptor related protein 12 2 2
MIRT567008 KLHL15 kelch like family member 15 2 2
MIRT567050 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT567112 ITGB1 integrin subunit beta 1 2 2
MIRT567542 FGFR1OP FGFR1 oncogene partner 2 2
MIRT567627 FAM210A family with sequence similarity 210 member A 2 2
MIRT567684 EIF4A2 eukaryotic translation initiation factor 4A2 2 2
MIRT567915 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT571014 CKAP2 cytoskeleton associated protein 2 2 2
MIRT571220 F2R coagulation factor II thrombin receptor 2 2
MIRT571678 RRAS2 RAS related 2 2 2
MIRT571693 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT571723 RPL17-C18orf32 RPL17-C18orf32 readthrough 2 2
MIRT571860 NKIRAS1 NFKB inhibitor interacting Ras like 1 2 2
MIRT572045 GPR137B G protein-coupled receptor 137B 2 2
MIRT572209 C18orf32 chromosome 18 open reading frame 32 2 2
MIRT573375 LIMA1 LIM domain and actin binding 1 2 2
MIRT573707 RBM12B RNA binding motif protein 12B 2 2
MIRT573915 SNAP47 synaptosome associated protein 47 2 2
MIRT574719 HAUS8 HAUS augmin like complex subunit 8 2 2
MIRT610998 BRI3BP BRI3 binding protein 2 2
MIRT615446 FAXC failed axon connections homolog 2 2
MIRT616437 FAM126B family with sequence similarity 126 member B 2 2
MIRT624424 CBX8 chromobox 8 2 2
MIRT625079 C15orf41 chromosome 15 open reading frame 41 2 2
MIRT628867 KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 2 2
MIRT630570 SOWAHA sosondowah ankyrin repeat domain family member A 2 4
MIRT634454 PAK6 p21 (RAC1) activated kinase 6 2 2
MIRT640010 OSTM1 osteopetrosis associated transmembrane protein 1 2 2
MIRT641800 USP32 ubiquitin specific peptidase 32 2 2
MIRT663408 SYT17 synaptotagmin 17 2 2
MIRT664793 LIAS lipoic acid synthetase 2 4
MIRT672157 PLEKHH1 pleckstrin homology, MyTH4 and FERM domain containing H1 2 2
MIRT679620 RRP36 ribosomal RNA processing 36 2 2
MIRT682524 GJD3 gap junction protein delta 3 2 2
MIRT684063 FOLR1 folate receptor 1 2 2
MIRT688711 CPS1 carbamoyl-phosphate synthase 1 2 2
MIRT691249 DFNB59 pejvakin 2 2
MIRT693152 THEM4 thioesterase superfamily member 4 2 2
MIRT693198 MKI67 marker of proliferation Ki-67 2 2
MIRT700440 PURB purine rich element binding protein B 2 2
MIRT701591 MYPN myopalladin 2 2
MIRT701966 MINK1 misshapen like kinase 1 2 2
MIRT702051 METTL21A methyltransferase like 21A 2 2
MIRT702588 JARID2 jumonji and AT-rich interaction domain containing 2 2 2
MIRT722312 DHCR24 24-dehydrocholesterol reductase 2 2
MIRT725222 PEA15 phosphoprotein enriched in astrocytes 15 2 2
MIRT755772 RAD51 RAD51 recombinase 5 1
MIRT755773 XRCC3 X-ray repair cross complementing 3 5 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4796-3p 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4796-3p Erlotinib 176870 NSC718781 approved sensitive High Non-Small Cell Lung Cancer tissue
hsa-miR-4796-3p Gefitinib 123631 NSC715055 approved sensitive High Non-Small Cell Lung Cancer tissue
hsa-miR-4796-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4796-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-4796-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4796-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)
hsa-miR-4796-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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