miRTarBase - #MIRT241379


—
pre-miRNA Information
pre-miRNA hsa-mir-514b   
Genomic Coordinates chrX: 147250151 - 147250230
Description Homo sapiens miR-514b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-514b-3p
Sequence 50| AUUGACACCUCUGUGAGUGGA |70
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs781802101 2 dbSNP
rs1484126326 11 dbSNP
rs906213497 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol QSER1   
Synonyms -
Description glutamine and serine rich 1
Transcript NM_001076786   
Expression
Putative miRNA Targets on QSER1
3'UTR of QSER1
(miRNA target sites are highlighted)		 
>QSER1|NM_001076786|3'UTR
   1 CTTTTCCACAAAAATCCCATCTTTTTATAGCACTAATGAAATGGCAGATATGGGGTGGTCAAAGATAATCAGATGTCAAG
  81 TAGTGGCCTTCTGCAGGCCGGCCGCTTCCATCATGGAACTGTCATTACCACCTCTGCTGAAGGACAGTGGTGCGGCCTTT
 161 AGGAACGAAGTTAGTCCTCTGGAAATGGACCTAAATCCCACCACATTTTTACCCTAATGAATGATTTTTCTATTTTGTAA
 241 ACCATTGGGTAACTTGAGTCATATTTTCAGAAACATTTTTTGACAAATGATGAAGCATGCACTAAGTATAATTTTTTTTT
 321 ATTGCTAGAGAAGTAACACTTAAAGTAACGATTTTTTTTTTCTGACTCCGGCTAAACACCAGAATGACAGAGAAGTGGCA
 401 GAAACCATATGTTTGTACTCACATCTGGCCACAAAACCAGAAATACTGTACATTATGTAAAGAGGTCTGGTGTGGTGTGA
 481 CATCCTGTATAAGAATATCATCAATTTAAAATATAAAATTTGGAAACTATTCTGCTTTACAGACTCCTTTTACTCTTAAC
 561 ATGTTCAGGAAACTGGATGTGGAATTGGTGCAATTCTCTGACTGCTTTTTGTGTCAAATTATATTGTGATAAAAAAACAA
 641 TGACATACTATTTTCCCTATCGCAAAGAAAAGTATTTTCGTTTATACTGTTTTTTCCTTTGGAAAATTTTCAATTGTACA
 721 TTTTATTTCACTGATAGTTGTATTTTTCACAAGGAAAATGTTGTGGTTATAATTACGTTTGATATATCTCTACAACACCT
 801 TTTGTTATTTTCAGTAAATCTTAGTTATATGTTGAATTTCTAATGTGAATTCTATCTTGAGGTAACCATTTTTTTCATAC
 881 AGATTTGCTTCAGTGTTATCCAGAATATGCATTCAGTACTAGAATTAGTTTAGCTTTATAAATAGGGCTGTGTTAGACAC
 961 TGCAGTAATTTTCTAATTCATAAAATAAACTTCTTACTAAACTAGCACTTGATTAACTTGTTGAGGTAAAAATCTAACTA
1041 CATTTACATTTTGAAGAATAAAACTGATAATTAGACTATTTGCAGTGTTAAACACAGCTTCCTTAACTCTTAGAACTGGA
1121 AGTTGTAGAGCTCTCCTTTTGGTGCCTTTCCAGCCTTTATACACACTATTGTAGCTTTCTTAGGTTTGATAGGTAGCGTT
1201 TCAAGTAGTTTAGCTGAGACAGTGAATGTATTAGGTTCAACATGACCTTGTGTTTTATTTGTGTTTGCCAACAGGATGCC
1281 TTATTTGTTTGAGAAAAAGATGTACTAGTGTCATTCTAAACTATCTCCTTTTTTAGGATTCTAAAGAAGTTAATCATCAT
1361 CCTTTTGTTTATTTTACCACCATTTAGTGCCTTAAATCCTATCAAGAAAGCAGTGTTACTGCTCAATGCCCAAATAAGAC
1441 ACGCGGATATTGCTATTGTCTTGCTTTTGAGTTAACAGGCCAACTTTTTATACTTAAAACCTCAGTAAACTGGCAAAGAA
1521 TTGAAGGTAATGTGATTTGATTTGAGAATAAAACATTGTAGCATTGGGTGAAAAATGAGTATTTGAGTTAAGCTTACATA
1601 TTTATTTCTGATGGTTATCTTATTAAAAGCAATAATCCTTAATACTGTACTTGCCATTAGACTAGGTACTCAGTAATGGA
1681 AGTTTCTCTCAAGGGTTAAATGTTCCATTTTTGAAAGTTTTAAAAAACCTGTTTGGGTGGTTTATTTTGAAAACAAAAGT
1761 AACCTATTAGATTCATTTTGCCTAACTCATATGAGAGATGCAGAGTATCAACAGTGGGAGCATCATAAAATGAATTTTCC
1841 AAGTGGAGAGGAGTAGGAAGCAGCCATATGATAGTATTGACTCTGGACAGAATTGATGTCTTTCGTTTCCAAAGTGCAGA
1921 GTAGGGAACTACATTTCCTAATGTGGCATTGTAAATATACATCTTTATATTACTCTTCCAGCCTACGTTCCTAAATCATT
2001 GATAATTTAAATATTTTTTAAAGCCACCTTAATTTAGGTAGCTCTTGGAATCGATGTTTGAATTCACTAGCCACATTTTC
2081 TTCATGATATGCCTCGTGGCAAACAAAGATGTTTCCTTAAGATGAATCTTACATTTCCCATAGAAAATAACCCATTTCCT
2161 TTGGCACTGCAGTTGCCCTCAAACTGCTTGCAGTTGTATTCATTTTAGTACAACAAAGGTTTTCATAATATGGGAGGCCA
2241 AGTCTATGATACTGCCTCAAAGAGACCCTATTGTGTAGATGCATCATCTTCTCTCATTTGATCCATAGAGCATAGGCAAA
2321 GATGTCAACCTCAGGCCTTAGAGAAAAGTGGAAATGTTATTATGACAGCCGTCCATGAGTTATCGCTTTGTATGAAGTTA
2401 AATACAGTCATGCGTTGCTTAACAGCAGGGATACATTCTGAGAAATGCATTGTTAGGCAATTCCGTTGTGCGAACATCCT
2481 AGTGTACTTACACAAACCTAGGTGGCATAGCCCACAACGTACCCAGGCTATATGGTAAACCTGTACAGCATGTTACTGTA
2561 CTGAATACTGTAGGCAGTTGTAACACAATGGTATTTGTGTATCTAGACATAGAAAACATACAGTAAGAATATGGTATTAT
2641 AATCTTACGGGACCACTGTCAAATACGCGGTCTGTCTTTGAAAAGTTGTAATGCGGCGCATGACTATAAATACCTAGCTG
2721 GTTAGCATTTACATTCCTTGCCAGGGAGTTTGAAATTTATACTATAGAAATAACTTTAGGTTTTAGGTAGAGTTAAAGAG
2801 GTAAAGCACATGTTGCCACAACCCAGGAAAGTATTTTTAAGAAAGATTGGATTTTCCTACCTTTAGAGATCTAAAAAAAA
2881 TTTAATATAAAAAATCATTTTGTGTTGGTGTTTATTACTAGTTCAGATGAGTGGCTGCTGAAGGGGCCCCCTTGTCATTT
2961 TCATTATAACCCAATTTCCACTTATTTGAACTCTTAAGTCATAAATGTATAATGACTTATGAATTAGCACAGTTAAGTTG
3041 ACACTAGAAACTGCCCATTTCTGTATTACACTATCAAATAGGAAACATTGGAAAGATGGGGAAAAAAATCTTATTTTAAA
3121 ATGGCTTAGAAAGTTTTCAGATTACTTTGAAAATTCTAAACTTCTTTCTGTTTCCAAAACTTGAAAATATGTAGATGGAC
3201 TCATGCATTAAGACTGTTTTCAAAGCTTTCCTCACATTTTTAAAGTGTGATTTTCCTTTTAATATACATATTTATTTTCT
3281 TTAAAGCAGCTATATCCCAACCCATGACTTTGGAGATATACCTATAAAACCAATATAACAGCAGGGTTATTGAAGCAGCT
3361 TTCTCAAATGTTGCTTCAGATGTGCAAGTTGCAAATTTTATTGTATTTGTAGAATACAATTTTTGTTTTAAACTGTATTT
3441 CAATCTATTTCTCCAAGATGCTTTTCATATAGAGTGAAATATCCCAGGATAACTGCTTCTGTGTCAGTCGCATTTGACGC
3521 ATAACTGCACAAATGAACAGTGTATACTCTTGGTTGTGCATTAACTTACATGTATAATTTTTGGCATCTGTGTTCACAAA
3601 TGCATGTGTTAGCAAATCACCTTTATTTATAAGTGACAATAATTGAAGTTAAGGATATAAAGAAACCTGCATTTGTAGTC
3681 CAGCGTTTTCATTTGGTCCATAACACAATGTATGGAAATGTGAAAGACAATTTTGTACATTTGTTTGTTACTAACTCAGA
3761 TCATTAAAATGAAAACAATTTTTTTAAACAAGAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aggUGAGUGUCU--C------CACAGUUa 5'
             |:|| | ||  |      ||||||| 
Target 5' gcaATTCTCTGACTGCTTTTTGTGTCAAa 3'
 590 - 618 142.00 -10.20
2 
miRNA  3' agGUGAGUGUCUCCACAGUUa 5'
            :|:|::||   ||||:|| 
Target 5' acTATTTGCA---GTGTTAAa 3'
 1075 - 1092 136.00 -10.00
3 
miRNA  3' agGUGAGUGUCUCCACAGUUa 5'
            ||:  :|| || |||||| 
Target 5' agCATAGGCAAAGATGTCAAc 3'
 2309 - 2329 131.00 -9.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20077473 19 COSMIC
COSN30129226 22 COSMIC
COSN30151332 39 COSMIC
COSN30177463 104 COSMIC
COSN26750269 111 COSMIC
COSN20757262 146 COSMIC
COSN30504276 154 COSMIC
COSN8219494 154 COSMIC
COSN31538532 197 COSMIC
COSN30121736 249 COSMIC
COSN28747351 290 COSMIC
COSN28197999 360 COSMIC
COSN7003169 362 COSMIC
COSN32064599 483 COSMIC
COSN31569918 638 COSMIC
COSN31579140 638 COSMIC
COSN31960615 680 COSMIC
COSN31564867 819 COSMIC
COSN31524156 878 COSMIC
COSN8641526 998 COSMIC
COSN19659578 1033 COSMIC
COSN31549261 1275 COSMIC
COSN30163256 1502 COSMIC
COSN7003170 2097 COSMIC
COSN28639619 2613 COSMIC
COSN31591014 2624 COSMIC
COSN24475143 2668 COSMIC
COSN26583688 2737 COSMIC
COSN8641527 2886 COSMIC
COSN5260303 2950 COSMIC
COSN8535177 3103 COSMIC
COSN30165605 3536 COSMIC
COSN1529381 3548 COSMIC
COSN5907637 3553 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs747459202 1 dbSNP
rs1428216523 2 dbSNP
rs1219028239 5 dbSNP
rs201126266 7 dbSNP
rs778859008 10 dbSNP
rs750335676 17 dbSNP
rs758242480 22 dbSNP
rs779705417 27 dbSNP
rs1436895778 28 dbSNP
rs374908236 34 dbSNP
rs757786252 35 dbSNP
rs746755454 36 dbSNP
rs1225890688 38 dbSNP
rs768211652 44 dbSNP
rs201680626 46 dbSNP
rs1209354284 48 dbSNP
rs1256454367 52 dbSNP
rs1026133768 62 dbSNP
rs955204002 63 dbSNP
rs986607296 73 dbSNP
rs746136508 81 dbSNP
rs899664758 82 dbSNP
rs569055600 88 dbSNP
rs1249480566 93 dbSNP
rs963921824 100 dbSNP
rs367603924 101 dbSNP
rs925012376 102 dbSNP
rs934973509 104 dbSNP
rs1052221204 105 dbSNP
rs1353779415 121 dbSNP
rs1310252054 128 dbSNP
rs1247473979 140 dbSNP
rs545766144 147 dbSNP
rs750822081 154 dbSNP
rs558058376 155 dbSNP
rs1166618771 166 dbSNP
rs950238945 167 dbSNP
rs1045838476 168 dbSNP
rs1488283663 173 dbSNP
rs1186604527 182 dbSNP
rs890457812 186 dbSNP
rs1220279941 203 dbSNP
rs1265508316 206 dbSNP
rs906135497 207 dbSNP
rs1192916091 215 dbSNP
rs1248123232 231 dbSNP
rs1216853157 237 dbSNP
rs186501494 243 dbSNP
rs1356956433 246 dbSNP
rs1425289676 260 dbSNP
rs1273951694 261 dbSNP
rs761590945 269 dbSNP
rs995073994 275 dbSNP
rs1456119507 276 dbSNP
rs1290399541 279 dbSNP
rs1299492174 283 dbSNP
rs1443418829 290 dbSNP
rs534102849 295 dbSNP
rs554448255 297 dbSNP
rs1327236397 301 dbSNP
rs1389103234 303 dbSNP
rs994545538 305 dbSNP
rs79855050 311 dbSNP
rs1159506069 312 dbSNP
rs574243943 312 dbSNP
rs969521136 312 dbSNP
rs891176530 313 dbSNP
rs1401122258 314 dbSNP
rs1008071297 321 dbSNP
rs201014994 338 dbSNP
rs1018154793 339 dbSNP
rs1452119298 339 dbSNP
rs963869644 350 dbSNP
rs914884125 351 dbSNP
rs1039580520 352 dbSNP
rs946666396 352 dbSNP
rs921117742 354 dbSNP
rs79537186 362 dbSNP
rs79483362 363 dbSNP
rs1313905779 365 dbSNP
rs541857852 370 dbSNP
rs1321340237 371 dbSNP
rs933799177 387 dbSNP
rs555383687 389 dbSNP
rs956413318 399 dbSNP
rs988190555 412 dbSNP
rs547539501 421 dbSNP
rs80196731 423 dbSNP
rs949107734 424 dbSNP
rs1005367827 427 dbSNP
rs760581300 430 dbSNP
rs544339851 438 dbSNP
rs1036392220 445 dbSNP
rs1174106857 448 dbSNP
rs1454518492 452 dbSNP
rs980482444 471 dbSNP
rs1191725305 474 dbSNP
rs899145259 475 dbSNP
rs539515564 480 dbSNP
rs927507094 515 dbSNP
rs1240212278 518 dbSNP
rs564142036 524 dbSNP
rs1023864411 528 dbSNP
rs969553220 530 dbSNP
rs1003675198 534 dbSNP
rs1446652322 542 dbSNP
rs551521215 544 dbSNP
rs1282341050 545 dbSNP
rs1255291790 554 dbSNP
rs1449386871 556 dbSNP
rs1035596572 560 dbSNP
rs536943641 564 dbSNP
rs1038627063 569 dbSNP
rs956518056 579 dbSNP
rs1442360297 588 dbSNP
rs898717491 589 dbSNP
rs1380553895 590 dbSNP
rs1270283974 594 dbSNP
rs988284047 599 dbSNP
rs577771556 605 dbSNP
rs1343099769 623 dbSNP
rs914934249 627 dbSNP
rs773311260 631 dbSNP
rs1171523089 632 dbSNP
rs762903106 638 dbSNP
rs1420074907 639 dbSNP
rs1047061643 660 dbSNP
rs1187191812 662 dbSNP
rs540014438 663 dbSNP
rs1008354492 664 dbSNP
rs1486117641 666 dbSNP
rs1280140380 669 dbSNP
rs1303790260 674 dbSNP
rs145259310 680 dbSNP
rs766321653 681 dbSNP
rs1001079855 682 dbSNP
rs1213499407 687 dbSNP
rs933905559 690 dbSNP
rs1285420699 691 dbSNP
rs1415092464 692 dbSNP
rs1354419522 706 dbSNP
rs753520891 714 dbSNP
rs1377928848 715 dbSNP
rs867878543 719 dbSNP
rs908357556 729 dbSNP
rs1239439899 731 dbSNP
rs1190881268 732 dbSNP
rs529170462 738 dbSNP
rs1355073367 741 dbSNP
rs956795296 747 dbSNP
rs1408119873 751 dbSNP
rs1417540750 761 dbSNP
rs987835100 770 dbSNP
rs796582557 777 dbSNP
rs368484350 778 dbSNP
rs1481792876 783 dbSNP
rs1233789526 788 dbSNP
rs1204484621 789 dbSNP
rs1306268749 798 dbSNP
rs1045343278 800 dbSNP
rs548993370 811 dbSNP
rs1459776152 820 dbSNP
rs764771159 826 dbSNP
rs1238338911 832 dbSNP
rs1438710554 846 dbSNP
rs980515128 867 dbSNP
rs572215282 869 dbSNP
rs752263077 872 dbSNP
rs1373849794 876 dbSNP
rs1297365153 880 dbSNP
rs1440005034 895 dbSNP
rs1426745726 896 dbSNP
rs926343485 907 dbSNP
rs1461990224 909 dbSNP
rs1035225493 911 dbSNP
rs1416628498 916 dbSNP
rs374702947 917 dbSNP
rs531561992 947 dbSNP
rs190496822 977 dbSNP
rs1009338610 981 dbSNP
rs1409263841 984 dbSNP
rs920196588 986 dbSNP
rs1479954211 990 dbSNP
rs1468502283 991 dbSNP
rs1333802761 993 dbSNP
rs1401284776 998 dbSNP
rs1441839853 1008 dbSNP
rs1467600388 1009 dbSNP
rs149174664 1018 dbSNP
rs868283664 1021 dbSNP
rs183063973 1033 dbSNP
rs1277819326 1039 dbSNP
rs1317124184 1040 dbSNP
rs1306038038 1041 dbSNP
rs1021974322 1042 dbSNP
rs1369879129 1043 dbSNP
rs146723737 1048 dbSNP
rs1326436190 1065 dbSNP
rs1440046536 1066 dbSNP
rs1393884509 1067 dbSNP
rs1323964422 1068 dbSNP
rs1455595277 1070 dbSNP
rs975085827 1077 dbSNP
rs1300458323 1078 dbSNP
rs1345954911 1087 dbSNP
rs1158845463 1090 dbSNP
rs1047341701 1100 dbSNP
rs1417665244 1104 dbSNP
rs1027935617 1105 dbSNP
rs1321339700 1107 dbSNP
rs758778820 1110 dbSNP
rs955344416 1132 dbSNP
rs891155481 1134 dbSNP
rs778373840 1139 dbSNP
rs186991329 1141 dbSNP
rs1485992647 1142 dbSNP
rs899892786 1143 dbSNP
rs1457041904 1144 dbSNP
rs1202057894 1152 dbSNP
rs1247928539 1154 dbSNP
rs1478045124 1156 dbSNP
rs1233559355 1166 dbSNP
rs1368684390 1168 dbSNP
rs1000709709 1170 dbSNP
rs536933985 1172 dbSNP
rs892293276 1175 dbSNP
rs537801704 1185 dbSNP
rs1024832148 1186 dbSNP
rs1288460957 1187 dbSNP
rs1429127582 1197 dbSNP
rs970377287 1198 dbSNP
rs972145646 1199 dbSNP
rs1173266704 1203 dbSNP
rs556863477 1204 dbSNP
rs192906604 1211 dbSNP
rs1409581359 1220 dbSNP
rs1033435241 1222 dbSNP
rs576647515 1229 dbSNP
rs537795119 1240 dbSNP
rs920126558 1243 dbSNP
rs954865703 1248 dbSNP
rs1428541187 1251 dbSNP
rs576040848 1254 dbSNP
rs1184443854 1256 dbSNP
rs1449048364 1284 dbSNP
rs1280849751 1308 dbSNP
rs951560211 1322 dbSNP
rs1209816255 1324 dbSNP
rs35682114 1329 dbSNP
rs983060543 1332 dbSNP
rs1345649982 1340 dbSNP
rs1252964553 1343 dbSNP
rs912791035 1349 dbSNP
rs747510612 1352 dbSNP
rs1278577631 1353 dbSNP
rs557897914 1367 dbSNP
rs1327151623 1370 dbSNP
rs745374928 1372 dbSNP
rs1398457179 1388 dbSNP
rs1357593327 1391 dbSNP
rs1317125224 1395 dbSNP
rs1313873225 1398 dbSNP
rs1039687982 1399 dbSNP
rs1374194850 1402 dbSNP
rs1212615240 1404 dbSNP
rs1291495761 1405 dbSNP
rs921367925 1424 dbSNP
rs1170193577 1425 dbSNP
rs1451832587 1427 dbSNP
rs75129510 1429 dbSNP
rs114918008 1443 dbSNP
rs892320184 1444 dbSNP
rs560067042 1445 dbSNP
rs1046314817 1446 dbSNP
rs770009354 1456 dbSNP
rs906418788 1457 dbSNP
rs1001831002 1459 dbSNP
rs1424998734 1462 dbSNP
rs1033796888 1469 dbSNP
rs963073411 1470 dbSNP
rs1475269127 1471 dbSNP
rs1250888951 1472 dbSNP
rs1216801026 1474 dbSNP
rs1166524288 1485 dbSNP
rs995018867 1490 dbSNP
rs1406233356 1493 dbSNP
rs1163008443 1507 dbSNP
rs1294079766 1507 dbSNP
rs1363838216 1523 dbSNP
rs1026050865 1532 dbSNP
rs1414374794 1533 dbSNP
rs1339115008 1534 dbSNP
rs951538693 1535 dbSNP
rs1396329337 1536 dbSNP
rs183140578 1549 dbSNP
rs1462524888 1550 dbSNP
rs1418155744 1553 dbSNP
rs1298684713 1560 dbSNP
rs996536249 1564 dbSNP
rs775376596 1565 dbSNP
rs1325788220 1569 dbSNP
rs749410048 1577 dbSNP
rs1474004105 1581 dbSNP
rs912821898 1582 dbSNP
rs77688739 1599 dbSNP
rs1437181541 1606 dbSNP
rs1248275279 1615 dbSNP
rs1196853828 1618 dbSNP
rs975655375 1619 dbSNP
rs921305345 1626 dbSNP
rs1273856335 1638 dbSNP
rs936669104 1640 dbSNP
rs1054310545 1644 dbSNP
rs1354487633 1646 dbSNP
rs955186834 1649 dbSNP
rs986754973 1656 dbSNP
rs773173545 1657 dbSNP
rs1015888117 1693 dbSNP
rs961244740 1694 dbSNP
rs913961770 1703 dbSNP
rs760748638 1706 dbSNP
rs945212519 1718 dbSNP
rs562412949 1719 dbSNP
rs541135369 1723 dbSNP
rs1264445655 1725 dbSNP
rs1446947247 1727 dbSNP
rs1191470399 1729 dbSNP
rs930737643 1730 dbSNP
rs1469392013 1732 dbSNP
rs147943002 1733 dbSNP
rs1195466751 1748 dbSNP
rs1454650106 1756 dbSNP
rs767867014 1762 dbSNP
rs980838734 1764 dbSNP
rs1213082532 1767 dbSNP
rs1473233013 1769 dbSNP
rs1345695228 1779 dbSNP
rs551319726 1785 dbSNP
rs1183278090 1793 dbSNP
rs1206116220 1802 dbSNP
rs926656211 1802 dbSNP
rs12364381 1804 dbSNP
rs937968334 1817 dbSNP
rs1055032660 1822 dbSNP
rs776568386 1840 dbSNP
rs898854831 1842 dbSNP
rs1237235850 1847 dbSNP
rs994484802 1869 dbSNP
rs565427373 1870 dbSNP
rs368805606 1871 dbSNP
rs548007005 1887 dbSNP
rs886151616 1894 dbSNP
rs567781600 1897 dbSNP
rs1432838972 1898 dbSNP
rs1358457447 1901 dbSNP
rs187783790 1905 dbSNP
rs1019830395 1906 dbSNP
rs1340893723 1935 dbSNP
rs1394330370 1950 dbSNP
rs550498745 1956 dbSNP
rs147116707 1958 dbSNP
rs1312409290 1959 dbSNP
rs1243898541 1965 dbSNP
rs1194217077 1970 dbSNP
rs1378662066 1974 dbSNP
rs1240170000 1976 dbSNP
rs759202908 1979 dbSNP
rs559454451 1987 dbSNP
rs752105214 1988 dbSNP
rs1217951707 1996 dbSNP
rs996567328 2003 dbSNP
rs147265575 2005 dbSNP
rs1028564195 2012 dbSNP
rs1337883624 2016 dbSNP
rs1314495088 2029 dbSNP
rs1415125410 2030 dbSNP
rs958295882 2035 dbSNP
rs1374799036 2042 dbSNP
rs1173927597 2045 dbSNP
rs1203939430 2049 dbSNP
rs989454888 2050 dbSNP
rs557464119 2053 dbSNP
rs913994269 2054 dbSNP
rs945497063 2084 dbSNP
rs1477627722 2085 dbSNP
rs1261221987 2091 dbSNP
rs1443309465 2094 dbSNP
rs1190555158 2096 dbSNP
rs982157481 2097 dbSNP
rs1203471646 2101 dbSNP
rs1257213664 2118 dbSNP
rs577694273 2122 dbSNP
rs868201913 2125 dbSNP
rs927824240 2129 dbSNP
rs1440043409 2131 dbSNP
rs1273114047 2133 dbSNP
rs1213408227 2134 dbSNP
rs937832584 2135 dbSNP
rs890800454 2137 dbSNP
rs1294695178 2138 dbSNP
rs1233502004 2156 dbSNP
rs1008275162 2157 dbSNP
rs879149825 2161 dbSNP
rs1300862231 2168 dbSNP
rs1444368873 2172 dbSNP
rs1354983072 2174 dbSNP
rs1241454969 2179 dbSNP
rs192409776 2183 dbSNP
rs1465135554 2199 dbSNP
rs185556119 2201 dbSNP
rs1167419457 2202 dbSNP
rs1475653941 2212 dbSNP
rs1363336501 2220 dbSNP
rs1413592893 2221 dbSNP
rs1180423218 2235 dbSNP
rs117974426 2251 dbSNP
rs1197482842 2257 dbSNP
rs1456106950 2260 dbSNP
rs1174198492 2267 dbSNP
rs1402860187 2276 dbSNP
rs1047362646 2278 dbSNP
rs961630474 2279 dbSNP
rs141637159 2280 dbSNP
rs1008673467 2286 dbSNP
rs1026847805 2287 dbSNP
rs79679450 2290 dbSNP
rs530714699 2307 dbSNP
rs1305637319 2311 dbSNP
rs1333532240 2314 dbSNP
rs1444436702 2315 dbSNP
rs1398282512 2340 dbSNP
rs150096811 2341 dbSNP
rs1462173279 2342 dbSNP
rs1349450272 2345 dbSNP
rs960744983 2348 dbSNP
rs1421199251 2350 dbSNP
rs992610215 2351 dbSNP
rs1438378824 2352 dbSNP
rs879286940 2355 dbSNP
rs113893908 2371 dbSNP
rs189367997 2372 dbSNP
rs1043929554 2385 dbSNP
rs141687298 2386 dbSNP
rs1317336802 2388 dbSNP
rs541191833 2391 dbSNP
rs769512616 2405 dbSNP
rs1373014506 2410 dbSNP
rs925474823 2412 dbSNP
rs561387449 2414 dbSNP
rs78828707 2415 dbSNP
rs1292052395 2416 dbSNP
rs1196648554 2417 dbSNP
rs1250105121 2425 dbSNP
rs746244996 2432 dbSNP
rs890904037 2436 dbSNP
rs753407667 2461 dbSNP
rs1158404805 2465 dbSNP
rs966680140 2466 dbSNP
rs76835603 2467 dbSNP
rs1037128569 2472 dbSNP
rs1193758306 2473 dbSNP
rs928018961 2475 dbSNP
rs1264629197 2480 dbSNP
rs1187964737 2489 dbSNP
rs937845148 2516 dbSNP
rs780355852 2519 dbSNP
rs146240047 2520 dbSNP
rs969880178 2524 dbSNP
rs34647285 2531 dbSNP
rs1047659567 2543 dbSNP
rs1384193063 2548 dbSNP
rs1173987183 2551 dbSNP
rs139313343 2556 dbSNP
rs1465801368 2560 dbSNP
rs557515088 2562 dbSNP
rs1398503597 2566 dbSNP
rs944344647 2572 dbSNP
rs1377824878 2577 dbSNP
rs1174875917 2578 dbSNP
rs571170580 2579 dbSNP
rs900231315 2582 dbSNP
rs1393925688 2587 dbSNP
rs1428748895 2589 dbSNP
rs997438313 2591 dbSNP
rs966660365 2593 dbSNP
rs553871905 2598 dbSNP
rs1486557051 2601 dbSNP
rs1257926494 2605 dbSNP
rs1049955866 2610 dbSNP
rs1199870732 2620 dbSNP
rs925505959 2621 dbSNP
rs893950036 2635 dbSNP
rs1229619867 2647 dbSNP
rs12289337 2650 dbSNP
rs1277756759 2657 dbSNP
rs1011198139 2667 dbSNP
rs565815210 2668 dbSNP
rs142615108 2669 dbSNP
rs116763618 2670 dbSNP
rs191901256 2671 dbSNP
rs1299411243 2680 dbSNP
rs1337710781 2681 dbSNP
rs1462006895 2686 dbSNP
rs536081158 2694 dbSNP
rs1422256186 2695 dbSNP
rs1211704349 2698 dbSNP
rs768761239 2699 dbSNP
rs1418382336 2701 dbSNP
rs1186507521 2712 dbSNP
rs930925219 2720 dbSNP
rs959455280 2721 dbSNP
rs1490157847 2726 dbSNP
rs991298951 2733 dbSNP
rs905810535 2734 dbSNP
rs920461625 2739 dbSNP
rs1428856092 2743 dbSNP
rs951967607 2746 dbSNP
rs1001443741 2759 dbSNP
rs1370930730 2761 dbSNP
rs1244463846 2765 dbSNP
rs1035962833 2766 dbSNP
rs895622636 2767 dbSNP
rs1459179839 2775 dbSNP
rs1399000661 2778 dbSNP
rs983398910 2783 dbSNP
rs555919953 2790 dbSNP
rs1364462294 2791 dbSNP
rs907757151 2796 dbSNP
rs577955957 2799 dbSNP
rs1301792409 2801 dbSNP
rs944354484 2802 dbSNP
rs1394680526 2817 dbSNP
rs575968000 2823 dbSNP
rs1020999560 2826 dbSNP
rs1342941429 2829 dbSNP
rs1182489014 2833 dbSNP
rs1439003912 2834 dbSNP
rs1237651986 2846 dbSNP
rs966690123 2848 dbSNP
rs1470015462 2851 dbSNP
rs544993238 2858 dbSNP
rs921584297 2865 dbSNP
rs1032303166 2866 dbSNP
rs931775398 2874 dbSNP
rs1054611563 2878 dbSNP
rs894009695 2881 dbSNP
rs772049566 2882 dbSNP
rs1042621382 2888 dbSNP
rs1306463428 2908 dbSNP
rs778922736 2909 dbSNP
rs1322538875 2910 dbSNP
rs902749507 2928 dbSNP
rs944194731 2941 dbSNP
rs1158962081 2947 dbSNP
rs1419022972 2948 dbSNP
rs1378357314 2952 dbSNP
rs1156949754 2966 dbSNP
rs1455675727 2971 dbSNP
rs1247331472 2972 dbSNP
rs868517758 2982 dbSNP
rs1264316467 2986 dbSNP
rs1217721195 2994 dbSNP
rs1353662388 2999 dbSNP
rs1035012807 3007 dbSNP
rs1237118106 3007 dbSNP
rs931040665 3010 dbSNP
rs1287994661 3017 dbSNP
rs1048127083 3021 dbSNP
rs905516274 3031 dbSNP
rs1327756337 3032 dbSNP
rs1486163658 3042 dbSNP
rs1298610275 3044 dbSNP
rs1399109629 3051 dbSNP
rs1185707037 3064 dbSNP
rs4756402 3071 dbSNP
rs1358362234 3076 dbSNP
rs1259443632 3080 dbSNP
rs1414964204 3098 dbSNP
rs937271002 3102 dbSNP
rs558790438 3103 dbSNP
rs1012370683 3108 dbSNP
rs895642730 3109 dbSNP
rs746942906 3126 dbSNP
rs951919567 3127 dbSNP
rs1194879685 3133 dbSNP
rs1025965844 3145 dbSNP
rs147259394 3161 dbSNP
rs868215874 3161 dbSNP
rs1261446199 3162 dbSNP
rs573829795 3162 dbSNP
rs902644734 3165 dbSNP
rs572352281 3166 dbSNP
rs1277296841 3167 dbSNP
rs541376300 3173 dbSNP
rs1362989690 3180 dbSNP
rs561409113 3182 dbSNP
rs907809731 3191 dbSNP
rs965982370 3207 dbSNP
rs1317995474 3211 dbSNP
rs975980747 3216 dbSNP
rs1217598771 3218 dbSNP
rs1211158252 3223 dbSNP
rs954017237 3226 dbSNP
rs1294888608 3237 dbSNP
rs986133167 3243 dbSNP
rs1333628735 3258 dbSNP
rs921658726 3266 dbSNP
rs1360377166 3268 dbSNP
rs530216602 3269 dbSNP
rs1402523973 3270 dbSNP
rs1171710640 3277 dbSNP
rs1477617096 3283 dbSNP
rs544056652 3290 dbSNP
rs1422008230 3301 dbSNP
rs931633470 3307 dbSNP
rs1398180599 3320 dbSNP
rs771002734 3321 dbSNP
rs1473428200 3327 dbSNP
rs1237358753 3329 dbSNP
rs914267821 3334 dbSNP
rs946904324 3336 dbSNP
rs776514891 3341 dbSNP
rs902675846 3345 dbSNP
rs939628369 3347 dbSNP
rs1315621039 3351 dbSNP
rs918753985 3355 dbSNP
rs952471849 3374 dbSNP
rs1378379773 3375 dbSNP
rs983846216 3380 dbSNP
rs759433733 3385 dbSNP
rs1311636843 3402 dbSNP
rs1057113490 3404 dbSNP
rs1317408434 3410 dbSNP
rs1444259397 3420 dbSNP
rs80051611 3434 dbSNP
rs1332118007 3448 dbSNP
rs926966158 3467 dbSNP
rs1215039063 3468 dbSNP
rs895181068 3469 dbSNP
rs936984864 3470 dbSNP
rs1398323867 3471 dbSNP
rs769515900 3474 dbSNP
rs1406364581 3479 dbSNP
rs1012625605 3482 dbSNP
rs1027740386 3489 dbSNP
rs1180692524 3490 dbSNP
rs144162603 3494 dbSNP
rs1484087628 3495 dbSNP
rs917208471 3496 dbSNP
rs1177397974 3502 dbSNP
rs1004960243 3503 dbSNP
rs1456194119 3505 dbSNP
rs552616745 3508 dbSNP
rs1221820655 3510 dbSNP
rs945951625 3511 dbSNP
rs779972269 3519 dbSNP
rs557720669 3520 dbSNP
rs576719733 3528 dbSNP
rs762759929 3531 dbSNP
rs976033027 3541 dbSNP
rs1374729196 3542 dbSNP
rs748359113 3543 dbSNP
rs1420183297 3545 dbSNP
rs1437447341 3564 dbSNP
rs1349720747 3566 dbSNP
rs1158957807 3570 dbSNP
rs1422064689 3576 dbSNP
rs148499889 3590 dbSNP
rs770086849 3591 dbSNP
rs1053774470 3600 dbSNP
rs889786470 3621 dbSNP
rs1437333037 3624 dbSNP
rs1268804641 3630 dbSNP
rs1191479620 3632 dbSNP
rs1487948899 3636 dbSNP
rs1244781998 3640 dbSNP
rs1006856920 3650 dbSNP
rs1029292848 3655 dbSNP
rs1285277467 3656 dbSNP
rs1471123992 3657 dbSNP
rs1351680808 3677 dbSNP
rs1303481442 3678 dbSNP
rs1337823266 3685 dbSNP
rs953076964 3686 dbSNP
rs1292179411 3694 dbSNP
rs1402185539 3696 dbSNP
rs1361546565 3698 dbSNP
rs1450770888 3708 dbSNP
rs965694744 3710 dbSNP
rs1311523114 3711 dbSNP
rs1374083591 3720 dbSNP
rs990200098 3742 dbSNP
rs1378919348 3750 dbSNP
rs994400633 3758 dbSNP
rs1432243370 3768 dbSNP
rs1304697826 3771 dbSNP
rs1025832986 3779 dbSNP
rs952835175 3779 dbSNP
rs184330814 3786 dbSNP
rs926997404 3790 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 79832.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aggugagugucucCACAGUUa 5'
                       ||||||| 
Target 5' ---acugcuuuuuGUGUCAAa 3'
 		1 - 18
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000399302.2 | 3UTR | ACUGCUUUUUGUGUCAAAUUAUAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
53 hsa-miR-514b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT241379 QSER1 glutamine and serine rich 1 2 2
MIRT444703 ZNF772 zinc finger protein 772 2 2
MIRT445153 VNN3 vanin 3 2 2
MIRT446418 ABHD2 abhydrolase domain containing 2 2 2
MIRT450012 NPHP3 nephrocystin 3 2 2
MIRT450275 LMBRD2 LMBR1 domain containing 2 2 2
MIRT456296 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT497427 SEC63 SEC63 homolog, protein translocation regulator 2 2
MIRT497573 PTCHD4 patched domain containing 4 2 2
MIRT497930 SCO1 SCO1, cytochrome c oxidase assembly protein 2 2
MIRT504844 HAUS3 HAUS augmin like complex subunit 3 2 6
MIRT525184 ZNF257 zinc finger protein 257 2 2
MIRT526074 TMEM41B transmembrane protein 41B 2 2
MIRT528581 PTGER3 prostaglandin E receptor 3 2 2
MIRT529572 IGBP1 immunoglobulin binding protein 1 2 4
MIRT532528 NDFIP2 Nedd4 family interacting protein 2 2 2
MIRT535625 NR2E1 nuclear receptor subfamily 2 group E member 1 2 4
MIRT536224 LRP6 LDL receptor related protein 6 2 2
MIRT536892 HEPHL1 hephaestin like 1 2 2
MIRT536951 HAS3 hyaluronan synthase 3 2 2
MIRT539334 AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 2 2
MIRT541765 ROBO2 roundabout guidance receptor 2 2 2
MIRT545082 ICT1 mitochondrial ribosomal protein L58 2 2
MIRT546399 SRP9 signal recognition particle 9 2 2
MIRT548872 CEP55 centrosomal protein 55 2 4
MIRT550702 TP53RK TP53 regulating kinase 2 4
MIRT555944 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT556010 MYLIP myosin regulatory light chain interacting protein 2 2
MIRT557873 FEM1B fem-1 homolog B 2 4
MIRT558905 CBX5 chromobox 5 2 2
MIRT562059 KLHL15 kelch like family member 15 2 2
MIRT562461 CORO1C coronin 1C 2 2
MIRT565656 SIX1 SIX homeobox 1 2 2
MIRT567036 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT571580 TXNIP thioredoxin interacting protein 2 2
MIRT613573 YY2 YY2 transcription factor 2 2
MIRT614610 MVK mevalonate kinase 2 2
MIRT615433 ZFP82 ZFP82 zinc finger protein 2 2
MIRT616333 ZNF699 zinc finger protein 699 2 2
MIRT622846 PDGFA platelet derived growth factor subunit A 2 2
MIRT626308 ABCC9 ATP binding cassette subfamily C member 9 2 2
MIRT637941 SIGLEC9 sialic acid binding Ig like lectin 9 2 2
MIRT639156 LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2 2
MIRT639691 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT644937 ATXN3L ataxin 3 like 2 2
MIRT648260 ZNF582 zinc finger protein 582 2 2
MIRT648446 LEAP2 liver enriched antimicrobial peptide 2 2 2
MIRT651575 WDR26 WD repeat domain 26 2 2
MIRT666986 PDPN podoplanin 2 4
MIRT691007 CRTC3 CREB regulated transcription coactivator 3 2 2
MIRT705009 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT705046 C5orf15 chromosome 5 open reading frame 15 2 2
MIRT710355 TLL2 tolloid like 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-514b Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-miR-514b-3p Cisplatin 5460033 NSC119875 approved sensitive Low Colorectal Cancer cell line (LOVO)
hsa-miR-514b-3p Irinotecan 60838 NSC728073 approved sensitive Low Colorectal Cancer cell line (LOVO)
hsa-miR-514b-3p Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (M14) (1uM)
hsa-miR-514b-3p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (M14) (1uM)
hsa-miR-514b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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