miRTarBase - #MIRT244620


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pre-miRNA Information
pre-miRNA hsa-mir-5590   
Genomic Coordinates chr2: 134857820 - 134857873
Description Homo sapiens miR-5590 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-5590-5p
Sequence 1| UUGCCAUACAUAGACUUUAUU |21
Evidence Not_experimental
Experiments
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs553031425 1 dbSNP
rs1255264134 4 dbSNP
rs1205476379 9 dbSNP
rs1387316331 10 dbSNP
rs1031241138 11 dbSNP
rs1465409255 12 dbSNP
rs1227248415 18 dbSNP
rs1334861447 19 dbSNP
Putative Targets

Gene Information
Gene Symbol MCM4   
Synonyms CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21
Description minichromosome maintenance complex component 4
Transcript NM_005914   
Other Transcripts NM_182746   
Expression
Putative miRNA Targets on MCM4
3'UTR of MCM4
(miRNA target sites are highlighted)		 
>MCM4|NM_005914|3'UTR
   1 AGCCTTGTGAGCAAGGAAGGCTCCCTGCATGTCCTGCTTGCTGCACGCCACATGGGTGTGGTCTGCATCTCAGTTGGCCG
  81 CCATCAGTGTAAATAGAGCTTAAAGTCATGGTTTGGCTGCATAAAAATTTTCTAACTTGGGTTCAATATTTGTAGTGAAG
 161 TATCTGTTTTCATTTTTTTCACGTTATAAATAAAAATACTATGCTGGCCGGGCGCGGTGGCTCACACCTGTAATCCCAGC
 241 ACTTTGGGAGGCCAATGTGGGTGGATCATGAGGTCAGGAGTTCAAGACCAGCCTAGCCAAGATGGTGAAACCCCGTCTCT
 321 AGTAAAGATAACAAAAAATTAGCTGGGCTTGATGGCATGCGCCTGTAATCCCAGCTACTCGGGAGGTTGAGGCAGGAGAA
 401 TCGCTTAAACCCAGGCGGCAGAGGTTGCAGTGAGCCAAGATCGCGCCACTGCACTCCAGCCTCAGCAATAGAGTGAGACT
 481 GTCTCAAAAAAAAAAAAAAAAAAAAAACCTGCCAATTTTCAAACATACCGTAGAGATTATTTTCAGGTGCCATTTTATAG
 561 TATAGCAGCAGGGCTTTTACTCTGTGTATGCACAGATGCAGTCTGGGGCATGGTTTGTGTGCTGGACTTTCTCATGGCCA
 641 TCATCAGTATGCTTATGGATTTGATGACAGGCATAGCCTGGGCATATCACCTCATTGGTAAAGGGCTAGAGCCTTTCTTT
 721 TTTATGGCACTTCTTTTTTTGAGATAGGGTCTTACTCTGTCACCCTGGCTAGAGTACACTGGTACAATCACGGCTCAATG
 801 TAGGCTTAACCTCCTGGGCTCAGGTGTATGTCACTATGCCCGGCTACTTTTTGTATTTTTTGGTAGAGACGGCTTCGCCA
 881 CGTTGCCCAGGCTGCAAGCGATATGCCTAGGCTCAAGCGATCTGCCCACCTCAACTTCCGGAAGTGCTGAGATTACAGGT
 961 GTGAGCCACTGCACCCAGCCTTTGTTTTATTTTTTATTTTTTGAGAGGTATGATTCTTTCTAGAGATTTTTTCTCATGGC
1041 TACTATTAGATCAGGAATGGGTGATTGGAGATTATTAGATTCTAGGTTAACTTCTACCACTTTACCCTAATACATAAAAC
1121 TTTTTCCTAAATAAATGATGGAAGGAATAATACTTGGTTACCTGGCATTATTTTTCAGTAAGAAAAAAGCTTTACTAACC
1201 ACTACATTTATGGAAATTTGTAGGGGTAAGTATTTTATAGGTCATAAAAAACACCATAATATAACGAATCTCATTTTCTT
1281 TAAATGTGAATTAAATCCTAACAGTCATCTTTATAAAATGACCATAGGCTAAAATCTTACGTGTAAGTACTACTACAATA
1361 AATAATTTCTGAAACCTTTAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuAUUUC----AG-AUACAUACCGUu 5'
            ||:||    || | | ||||||| 
Target 5' gcTAGAGCCTTTCTTTTTTATGGCAc 3'
 705 - 730 153.00 -8.40
2 
miRNA  3' uuauuUCAGAUA-CAUACCGUu 5'
               | |:||| |||| ||| 
Target 5' gtgccATTTTATAGTATAGCAg 3'
 547 - 568 128.00 -6.30
3 
miRNA  3' uuAUUUCAG-AUACAUACCGUu 5'
            |::: ||  :|||||| || 
Target 5' ccTGGGCTCAGGTGTATGTCAc 3'
 813 - 834 123.00 -8.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
911995 38 ClinVar
909071 57 ClinVar
363239 72 ClinVar
909072 110 ClinVar
363240 126 ClinVar
909073 149 ClinVar
909074 198 ClinVar
363241 214 ClinVar
363242 215 ClinVar
363243 256 ClinVar
909926 316 ClinVar
909927 358 ClinVar
363244 359 ClinVar
363245 388 ClinVar
363246 439 ClinVar
909928 444 ClinVar
909929 454 ClinVar
363247 484 ClinVar
363248 486 ClinVar
363249 538 ClinVar
910827 820 ClinVar
910828 843 ClinVar
910829 851 ClinVar
363250 872 ClinVar
363251 878 ClinVar
363252 883 ClinVar
363253 956 ClinVar
363254 1135 ClinVar
912048 1141 ClinVar
912049 1235 ClinVar
363255 1257 ClinVar
912050 1267 ClinVar
363256 1305 ClinVar
COSN31561283 13 COSMIC
COSN30188550 32 COSMIC
COSN30118602 47 COSMIC
COSN31499061 48 COSMIC
COSN31612008 82 COSMIC
COSN1365340 86 COSMIC
COSN31600258 151 COSMIC
COSN28835894 180 COSMIC
COSN20076352 202 COSMIC
COSN28201671 695 COSMIC
COSN2524225 808 COSMIC
COSN8087398 1146 COSMIC
COSN23281608 1165 COSMIC
COSN2277129 1265 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs769325855 3 dbSNP
rs777485596 4 dbSNP
rs748978319 7 dbSNP
rs1362198360 9 dbSNP
rs770875230 11 dbSNP
rs770781970 14 dbSNP
rs774391513 17 dbSNP
rs945110138 22 dbSNP
rs759517494 26 dbSNP
rs577185177 28 dbSNP
rs1486227582 30 dbSNP
rs1190879565 32 dbSNP
rs1438945835 33 dbSNP
rs1265494155 38 dbSNP
rs776840124 42 dbSNP
rs762055149 44 dbSNP
rs374664211 47 dbSNP
rs377300189 48 dbSNP
rs1485114204 49 dbSNP
rs375801965 57 dbSNP
rs1017256592 68 dbSNP
rs898441660 70 dbSNP
rs17334535 72 dbSNP
rs1028565244 74 dbSNP
rs1167626176 76 dbSNP
rs772085764 80 dbSNP
rs574897579 81 dbSNP
rs890076958 95 dbSNP
rs1413953673 97 dbSNP
rs1008230073 98 dbSNP
rs1313709919 106 dbSNP
rs1436876525 107 dbSNP
rs1019587652 110 dbSNP
rs1463294003 123 dbSNP
rs886062979 126 dbSNP
rs1470776870 136 dbSNP
rs1300887597 137 dbSNP
rs541909905 147 dbSNP
rs117499589 149 dbSNP
rs775124491 152 dbSNP
rs760541542 156 dbSNP
rs987559996 160 dbSNP
rs1018915798 171 dbSNP
rs965067564 176 dbSNP
rs985062630 177 dbSNP
rs1212567770 180 dbSNP
rs1444976372 182 dbSNP
rs1282906948 183 dbSNP
rs1315806123 184 dbSNP
rs1352675787 186 dbSNP
rs974807033 195 dbSNP
rs17334542 198 dbSNP
rs957669733 201 dbSNP
rs1294954345 202 dbSNP
rs1416821188 209 dbSNP
rs988916827 210 dbSNP
rs773569603 211 dbSNP
rs886062980 214 dbSNP
rs17287753 215 dbSNP
rs376086042 216 dbSNP
rs112854872 217 dbSNP
rs551825075 221 dbSNP
rs1254637194 223 dbSNP
rs1483203870 231 dbSNP
rs1184809153 242 dbSNP
rs1244418334 248 dbSNP
rs544019622 256 dbSNP
rs766551557 260 dbSNP
rs1448214514 264 dbSNP
rs898382350 267 dbSNP
rs1212965564 274 dbSNP
rs1335434090 290 dbSNP
rs903628563 293 dbSNP
rs1429942752 302 dbSNP
rs1046895192 303 dbSNP
rs1269834566 305 dbSNP
rs890964731 306 dbSNP
rs1367430482 311 dbSNP
rs1324028639 314 dbSNP
rs562097847 315 dbSNP
rs751753458 316 dbSNP
rs529806989 318 dbSNP
rs964854516 319 dbSNP
rs1408574356 325 dbSNP
rs1466468369 334 dbSNP
rs1419329296 357 dbSNP
rs1049961235 358 dbSNP
rs17287761 359 dbSNP
rs768121435 361 dbSNP
rs1019893214 362 dbSNP
rs1202100050 364 dbSNP
rs957828198 377 dbSNP
rs1273519958 378 dbSNP
rs1296987789 381 dbSNP
rs566566723 382 dbSNP
rs989031277 387 dbSNP
rs144432703 388 dbSNP
rs971535823 398 dbSNP
rs981604455 400 dbSNP
rs1216611752 406 dbSNP
rs1330016227 413 dbSNP
rs772339147 417 dbSNP
rs952945085 418 dbSNP
rs1312025637 425 dbSNP
rs139764001 427 dbSNP
rs1454337452 429 dbSNP
rs1396431174 432 dbSNP
rs1175399115 436 dbSNP
rs886062981 439 dbSNP
rs980157142 440 dbSNP
rs777224136 443 dbSNP
rs552183222 444 dbSNP
rs775104449 445 dbSNP
rs992013741 446 dbSNP
rs1207486350 449 dbSNP
rs917855872 451 dbSNP
rs945047640 454 dbSNP
rs978195033 455 dbSNP
rs1373289006 467 dbSNP
rs1280453135 473 dbSNP
rs1486635690 475 dbSNP
rs1189147793 476 dbSNP
rs886062982 484 dbSNP
rs1424172111 485 dbSNP
rs1491505484 485 dbSNP
rs869292313 485 dbSNP
rs1156370137 486 dbSNP
rs1187461936 486 dbSNP
rs1213762557 486 dbSNP
rs1257794204 486 dbSNP
rs1288250517 486 dbSNP
rs1316784103 486 dbSNP
rs1358379356 486 dbSNP
rs1486142213 486 dbSNP
rs1491588747 486 dbSNP
rs34372744 486 dbSNP
rs756109121 486 dbSNP
rs768805506 486 dbSNP
rs74784385 488 dbSNP
rs1480618698 489 dbSNP
rs79486865 490 dbSNP
rs1230845216 499 dbSNP
rs1020750225 500 dbSNP
rs925054972 504 dbSNP
rs1414989939 505 dbSNP
rs936380404 507 dbSNP
rs1452449749 508 dbSNP
rs77606589 508 dbSNP
rs1409593121 509 dbSNP
rs1456648899 511 dbSNP
rs1317726669 512 dbSNP
rs911364631 515 dbSNP
rs1188429763 525 dbSNP
rs944207873 525 dbSNP
rs190858646 530 dbSNP
rs897430082 531 dbSNP
rs1485583063 535 dbSNP
rs568975576 538 dbSNP
rs1242835965 545 dbSNP
rs1292040012 552 dbSNP
rs1211102843 559 dbSNP
rs1333389079 560 dbSNP
rs1272905449 564 dbSNP
rs1048834574 570 dbSNP
rs1047008690 574 dbSNP
rs891079823 583 dbSNP
rs1381356559 586 dbSNP
rs1362009610 591 dbSNP
rs1224450959 600 dbSNP
rs1285596203 610 dbSNP
rs1327616945 611 dbSNP
rs1322014612 618 dbSNP
rs1438569298 624 dbSNP
rs888460410 631 dbSNP
rs556325197 632 dbSNP
rs1393670716 639 dbSNP
rs1034414308 641 dbSNP
rs1459250792 645 dbSNP
rs1284320133 656 dbSNP
rs866929280 657 dbSNP
rs1448267657 662 dbSNP
rs1390831961 664 dbSNP
rs900562464 666 dbSNP
rs1245720704 668 dbSNP
rs17287768 672 dbSNP
rs996290573 677 dbSNP
rs1201234821 678 dbSNP
rs1489662212 688 dbSNP
rs1033394402 695 dbSNP
rs959181071 696 dbSNP
rs957371984 704 dbSNP
rs879001261 713 dbSNP
rs1299115919 722 dbSNP
rs1472213975 729 dbSNP
rs1370072426 736 dbSNP
rs1013400905 740 dbSNP
rs568122008 756 dbSNP
rs1408763701 760 dbSNP
rs1297433001 775 dbSNP
rs375999623 776 dbSNP
rs1461635591 778 dbSNP
rs1402480017 782 dbSNP
rs1024883439 792 dbSNP
rs967069533 793 dbSNP
rs1200167786 794 dbSNP
rs978038783 795 dbSNP
rs756962896 799 dbSNP
rs1305334285 804 dbSNP
rs535628498 808 dbSNP
rs1208362519 815 dbSNP
rs1346501825 817 dbSNP
rs1349073910 818 dbSNP
rs17287775 820 dbSNP
rs1280608889 833 dbSNP
rs1235286888 836 dbSNP
rs1333941390 837 dbSNP
rs1305969274 839 dbSNP
rs929618522 840 dbSNP
rs985186218 842 dbSNP
rs17287781 843 dbSNP
rs1433143549 844 dbSNP
rs148413389 851 dbSNP
rs943956114 856 dbSNP
rs1467981794 857 dbSNP
rs1362582058 862 dbSNP
rs192670035 872 dbSNP
rs918764461 877 dbSNP
rs184913079 878 dbSNP
rs1482631581 880 dbSNP
rs780070829 882 dbSNP
rs576678949 883 dbSNP
rs1278665614 891 dbSNP
rs1201698934 896 dbSNP
rs1348387783 897 dbSNP
rs1260083766 899 dbSNP
rs888419614 900 dbSNP
rs187525330 901 dbSNP
rs562399372 905 dbSNP
rs1135031 910 dbSNP
rs895937144 919 dbSNP
rs1013368833 920 dbSNP
rs550498249 923 dbSNP
rs1334846852 928 dbSNP
rs1416245013 930 dbSNP
rs1382969598 935 dbSNP
rs1414612630 940 dbSNP
rs966578690 940 dbSNP
rs999820296 941 dbSNP
rs1032279570 944 dbSNP
rs1474649544 950 dbSNP
rs1237710434 952 dbSNP
rs1188945582 955 dbSNP
rs529512295 956 dbSNP
rs548401944 957 dbSNP
rs985155200 958 dbSNP
rs1331176685 961 dbSNP
rs1446545061 967 dbSNP
rs1355825006 971 dbSNP
rs748749770 981 dbSNP
rs1284997985 987 dbSNP
rs1450533015 989 dbSNP
rs1324739271 1002 dbSNP
rs1317773663 1006 dbSNP
rs1313713919 1007 dbSNP
rs1436410627 1009 dbSNP
rs1391501417 1010 dbSNP
rs910968188 1011 dbSNP
rs1324236729 1012 dbSNP
rs974678722 1014 dbSNP
rs193030147 1020 dbSNP
rs776623464 1025 dbSNP
rs1026719855 1027 dbSNP
rs1382953701 1038 dbSNP
rs1247683234 1050 dbSNP
rs951136003 1053 dbSNP
rs763259958 1059 dbSNP
rs1188661054 1079 dbSNP
rs1466151660 1084 dbSNP
rs1251065323 1097 dbSNP
rs912247151 1103 dbSNP
rs1451951887 1106 dbSNP
rs943903889 1114 dbSNP
rs975359217 1115 dbSNP
rs976535010 1121 dbSNP
rs921220063 1130 dbSNP
rs1296905517 1132 dbSNP
rs11553127 1135 dbSNP
rs1440626042 1136 dbSNP
rs1054056643 1138 dbSNP
rs114521965 1139 dbSNP
rs1041666335 1140 dbSNP
rs946147767 1140 dbSNP
rs984760430 1145 dbSNP
rs13282970 1146 dbSNP
rs13254385 1147 dbSNP
rs910165537 1157 dbSNP
rs907214569 1162 dbSNP
rs1168593940 1168 dbSNP
rs13263180 1175 dbSNP
rs13263181 1176 dbSNP
rs1242578184 1183 dbSNP
rs1392781521 1185 dbSNP
rs1445271913 1190 dbSNP
rs1185521942 1197 dbSNP
rs1248201831 1201 dbSNP
rs13254657 1215 dbSNP
rs1034597618 1216 dbSNP
rs1274199542 1217 dbSNP
rs894746836 1221 dbSNP
rs1301409497 1226 dbSNP
rs1055760477 1231 dbSNP
rs1475209681 1232 dbSNP
rs1219129728 1235 dbSNP
rs376528376 1236 dbSNP
rs995673963 1237 dbSNP
rs1027175110 1240 dbSNP
rs895824296 1242 dbSNP
rs1308246676 1244 dbSNP
rs950105675 1246 dbSNP
rs17334549 1257 dbSNP
rs1336699340 1262 dbSNP
rs902320891 1263 dbSNP
rs999391650 1266 dbSNP
rs539412503 1267 dbSNP
rs1032662910 1296 dbSNP
rs1454074456 1303 dbSNP
rs17334556 1305 dbSNP
rs958212958 1308 dbSNP
rs1183139657 1309 dbSNP
rs1325422254 1322 dbSNP
rs1227797437 1325 dbSNP
rs1278219352 1331 dbSNP
rs989243772 1341 dbSNP
rs531643451 1342 dbSNP
rs1006560260 1350 dbSNP
rs774552958 1353 dbSNP
rs759687962 1355 dbSNP
rs767874777 1358 dbSNP
rs745498672 1363 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 4173.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uuauuucAG-AUACAUACCGUu 5'
                 || | | ||||||| 
Target 5' ---ccuuUCUUUUUUAUGGCAc 3'
 		1 - 19
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000523944.1 | 3UTR | CCUUUCUUUUUUAUGGCACUUCUUUUUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
69 hsa-miR-5590-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT056313 WAC WW domain containing adaptor with coiled-coil 2 6
MIRT066181 PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma 2 2
MIRT095612 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT099166 MYLIP myosin regulatory light chain interacting protein 2 2
MIRT107578 VLDLR very low density lipoprotein receptor 2 2
MIRT179602 CAPZA1 capping actin protein of muscle Z-line alpha subunit 1 2 8
MIRT241303 ZC3H12C zinc finger CCCH-type containing 12C 2 8
MIRT244620 MCM4 minichromosome maintenance complex component 4 2 2
MIRT270705 SBNO1 strawberry notch homolog 1 2 4
MIRT453616 SNRPE small nuclear ribonucleoprotein polypeptide E 2 4
MIRT453653 RAB6C RAB6C, member RAS oncogene family 2 2
MIRT464159 VMP1 vacuole membrane protein 1 2 15
MIRT477720 EEF1A1 eukaryotic translation elongation factor 1 alpha 1 2 2
MIRT484301 ENDOD1 endonuclease domain containing 1 2 4
MIRT496069 GLCCI1 glucocorticoid induced 1 2 2
MIRT496338 TMEM81 transmembrane protein 81 2 2
MIRT496653 PITPNM3 PITPNM family member 3 2 2
MIRT499098 DENND4C DENN domain containing 4C 2 8
MIRT499862 SVOP SV2 related protein 2 12
MIRT504913 CD38 CD38 molecule 2 4
MIRT515401 WDR72 WD repeat domain 72 2 4
MIRT518156 TMEM133 transmembrane protein 133 2 2
MIRT518558 GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 2 2
MIRT518636 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT518724 ABCG8 ATP binding cassette subfamily G member 8 2 2
MIRT524301 CTC1 CST telomere replication complex component 1 2 4
MIRT524472 CHRM3 cholinergic receptor muscarinic 3 2 4
MIRT527562 ADCY7 adenylate cyclase 7 2 2
MIRT532694 TCN2 transcobalamin 2 2 4
MIRT534640 RNF6 ring finger protein 6 2 2
MIRT537163 GGCX gamma-glutamyl carboxylase 2 2
MIRT539360 AFF4 AF4/FMR2 family member 4 2 2
MIRT547023 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT548155 FRAT2 FRAT2, WNT signaling pathway regulator 2 2
MIRT550127 ZNF138 zinc finger protein 138 2 2
MIRT558473 DBN1 drebrin 1 2 2
MIRT566862 LRRC58 leucine rich repeat containing 58 2 2
MIRT567246 HSP90AA1 heat shock protein 90 alpha family class A member 1 2 2
MIRT572848 BRPF3 bromodomain and PHD finger containing 3 2 2
MIRT574914 Vmp1 vacuole membrane protein 1 2 9
MIRT606849 RAB7A RAB7A, member RAS oncogene family 2 2
MIRT611274 RBMXL1 RNA binding motif protein, X-linked like 1 2 2
MIRT612328 TRPS1 transcriptional repressor GATA binding 1 2 2
MIRT612415 SP1 Sp1 transcription factor 2 2
MIRT614791 RRAGC Ras related GTP binding C 2 2
MIRT618449 SERPINA3 serpin family A member 3 2 2
MIRT621154 MICALCL MICAL C-terminal like 2 2
MIRT622141 SOX4 SRY-box 4 2 2
MIRT623504 KCNK5 potassium two pore domain channel subfamily K member 5 2 2
MIRT623598 IPO9 importin 9 2 2
MIRT624075 EBF1 early B-cell factor 1 2 2
MIRT639792 MVK mevalonate kinase 2 2
MIRT641109 ZNF274 zinc finger protein 274 2 2
MIRT641579 RFX1 regulatory factor X1 2 2
MIRT643095 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT645141 CUBN cubilin 2 2
MIRT646461 PRDM10 PR/SET domain 10 2 2
MIRT650815 HMOX1 heme oxygenase 1 2 2
MIRT653073 ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2 2
MIRT657675 GPR26 G protein-coupled receptor 26 2 2
MIRT665824 TIMM8B translocase of inner mitochondrial membrane 8 homolog B 2 2
MIRT695592 TMEM199 transmembrane protein 199 2 2
MIRT698039 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT701015 PCGF5 polycomb group ring finger 5 2 2
MIRT701357 NR4A3 nuclear receptor subfamily 4 group A member 3 2 2
MIRT707114 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT718661 HNF4A hepatocyte nuclear factor 4 alpha 2 2
MIRT719901 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT720564 C1RL complement C1r subcomponent like 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-5590-5p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)

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