miRTarBase - #MIRT252500


—
pre-miRNA Information
pre-miRNA hsa-mir-548ap   
Genomic Coordinates chr15: 85825635 - 85825730
Description Homo sapiens miR-548ap stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-548ap-3p
Sequence 58| AAAAACCACAAUUACUUUU |76
Evidence Not_experimental
Experiments
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 8 15 + 85825699 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1391959840 4 dbSNP
rs1164149363 6 dbSNP
rs150751643 7 dbSNP
rs1414633461 15 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol NWD1   
Synonyms -
Description NACHT and WD repeat domain containing 1
Transcript NM_001007525   
Expression
Putative miRNA Targets on NWD1
3'UTR of NWD1
(miRNA target sites are highlighted)		 
>NWD1|NM_001007525|3'UTR
   1 CAGTCCAGTTTGTCCATGCTGTGGTAAACAGAATCATCCCAACCACCAGTGGCTTCATTGCCCCCACCAGGCATGGTTAT
  81 CTGATCCGAGAGAATTTCCAGTGCCTTTCAGCAAAAGCCTCACCGCAGGACCCTCTTAAGAACTTCAAGAAGGCAATGTG
 161 GATGGTCAAATCCAGGCAGAGAGAGGAGCTAGTTGCAGCTGCAGGAGCTCCCCAGGACTTGGAGTCAGAAAGTGCCCAGG
 241 GAAATGAAACCAAATCAAACAAATGCTCACAAGTGTGCCTGATAGTGTAAAAAAATAAAAATAAAAAAACCCTGTGGGGG
 321 TATGGGGCTCCAGTGAGTTAGCCCCATTTAATCTAGTTAAAGCAAAAAGAATACGTTTGCTGGTGTATATCTGGACCCAT
 401 GGCTTCAGATTATGGCTTCAGACCTTGTCTCTTCTCATCTTTCCATTATTCTTTCCTCTTTTTCATTTTCATTCTCAGAC
 481 TTGCCACCCCCAGGTTAGCAACATGGTGGCCAATATGCTGCTGTCTCCAATTTCAATAGAAAAGAGAGCTTCTCTTTCCC
 561 AACAGTCCTAGCCTCAACTCTACTGGTCCCAATTGGCCCATACGCCTAGCCCTAAACCAATTATTATATCTGGGAGAATG
 641 CAGAGCTCTAATCGGCTAGACTGATCCAATGTCCACCACTGGGACTGAGAATAGAAGAGATTACTCCTGAGATGCAAACT
 721 GGAGTTCTGGTACCAGATGAAGGGGGAACGGATGAATGTGAGATACAGCAAATCACTGATGTGGACCACAGAACCTCACA
 801 GTTTATAAAGCTGTAGGTGCTGTCATCTGATCCTCATCACAACTCATACTTTAGGGAGGGCAGGAGTTTCTGTATCTATT
 881 TTACAGATGAGGAAACTGAGCCTTGCGGAAGTAGTTATAATTTGATTCAGGTCACAAGTCCAAGGTGCAAGAGCTCTGAG
 961 AGTGAGCCTTCTGTCCCATTCCTGTTAGACCTCACTCCAATTTCAGTCTGCAGAGCACAACCATCTCTTCCACAGGCACC
1041 ACACTCAAATGCTCACAGGAGCTAGTGACTAATCTAGACACTTCCATGCACCTGGGTGAGCAGCAGGGAGAGACAGAGAC
1121 TGGACATGTGGAAGGCAGAGATTGTGTCTAGGGTGGGTATGAGCAGCCTGACTGTAGCCCAGAATCACCATGGCCAAACA
1201 AGCCCACTGCTGTCAGTGCTTCCAGTTGTAATAAGCAAAGCCAGAAATCCAGACTTTTATGCAAAAATGTTCTGACTTTT
1281 AAAGTTGGCGATTGGTTGAATTTATATCTATAGTGCATTTGGCATGTGCGTCTTTGGTTAATGAGCTGACTTCAGGACTC
1361 ACGCTGGCAGTAAAACAATCAACATGTTATAGTTCATCCCTCTCTATTCCTTGGCTCCCAAACTTTTGGGATAAAGATGT
1441 GGGTTTTTAATCTTAAAAACTGGAGGCTCTTGGAAGTAGAAAGAGCTGCTGATCTCTCCCTGCTTTGCTTTTGAACTGTC
1521 TGCCTTGTGCAAGTTCAACAGTCAAACTGTTTTCATTCCACTTAAGTGGATCTTTCTTCTTTGCCCACAGCCTTCTAAAA
1601 GCCCTTCTCAGTCTTCTCAGGCTTTTACTTTAATGCTAGGATAGTCTAAATCTTCAAGGTGGCTATCCCTTCTCCCCTCC
1681 GTGGAATTCCTGATAGAGTCTCAATAAAAGCAACCTTAGAAACAGAGGCTTTTGAGCTGAACAAGACCCTACTGCTGTCT
1761 TATTCATCCATTTTCCAAACCAGTTTTCCAAGGCAGGTTTTGGTAGTTCTGCAAATGTTAGTGTCAAATTTCATTTAAAA
1841 ATATTTTAAACTGTAATTTTAAGATGTATGCTTGGATGTATTGGGCAGCAGCTTCTAAGGTGTTGAAGATTACTAAGGTT
1921 GGTGCAAAAAGTAACTGTGGTTTTCGCCATTAAAAATATTAAAAATAATGGCAAAAACTGGCTGGGCACAGTGGCTCACA
2001 CCTGTGGTCCCAGCTCTTTGGAAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGACAACATG
2081 GTGAAACCCTTCTCTACTAAAAATACAAAAATCAGCCAGGCATGGTGGTGAGTGCCTGTAATCTCAGTTACTCAGGAGGC
2161 TGAGTCAGGAGAATCACTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGTG
2241 ACAGAGCAAGACTCCATCTCATAATAATAATAATAATGGCAAAAGCCTCGGTGGCTCACGCCTGTAATCCCAGCACTTTG
2321 GGAGGCTGAGGCGGGTGGATCACTTGAGGCCAGGTGTTCAAGAGCAGCCTGGTCAACATGGTGAAACTCTGTCTCTACTC
2401 AAAAATACAAAAATTAGCCTGGTGTGGTGACGTACACCTGTAATTCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCT
2481 TGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCGCACCACTGCACTCCAGCATGAGTGACAGAGACTCTGTCTCCA
2561 AAAAAAAAAAAAAAAAAAAGTAATGGCAAAAACCACAATTAATTTTGCATCAACCTAATAATTTAGGATTCTTCTGCCAT
2641 TTTCATTTAACTGATTTAACTGAAGAGCCCAATTAAATTGTGAAGGGAGCCCTGAAAAAATTAGCTACTCTTTGCCACTG
2721 CTTCTCTGTGAATCAAGGGCTTACCCAATGCAGAAATAAAGTAGATGTTGAGACCAATTAAGATTTCACCTACAAATTCT
2801 GATTTTAAATGCCTGTGTCCATCTCCACAGCCTCAGTGAGAATTGATTGTTTTGTAGATAAATCCTAATTTAAACATTGG
2881 AAATGCCTTTTTACTAATAAAATGCTACAACAAATTATTGCTTAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuUUCAUUAACACCAAAAa 5'
            |||||| ||||||||| 
Target 5' aaAAGTAACTGTGGTTTTc 3'
 1927 - 1945 177.00 -15.80
2 
miRNA  3' uuuucaUUAACACCAAAAa 5'
                |: ||||| ||| 
Target 5' ggataaAGATGTGGGTTTt 3'
 1429 - 1447 121.00 -6.70
3 
miRNA  3' uuuUCAUUAACACCAaaaa 5'
             ||  || |||||    
Target 5' gccAGGCATGGTGGTgagt 3'
 2115 - 2133 96.00 -5.36
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM9350661 13 COSMIC
COSM8806494 19 COSMIC
COSM8150647 24 COSMIC
COSM6731865 25 COSMIC
COSM4446715 32 COSMIC
COSM7925360 36 COSMIC
COSM6217476 48 COSMIC
COSM7948724 52 COSMIC
COSM4446716 76 COSMIC
COSM6731868 88 COSMIC
COSM7785350 89 COSMIC
COSM992573 89 COSMIC
COSM5822279 90 COSMIC
COSM3285079 93 COSMIC
COSM7947383 93 COSMIC
COSM992574 109 COSMIC
COSM5706892 115 COSMIC
COSM4446717 122 COSMIC
COSM1750710 130 COSMIC
COSM1480735 161 COSMIC
COSM163038 170 COSMIC
COSM8124201 174 COSMIC
COSM7537741 177 COSMIC
COSM6731872 188 COSMIC
COSM8217221 197 COSMIC
COSM9669987 212 COSMIC
COSM8417196 215 COSMIC
COSM6731871 216 COSMIC
COSM9772052 216 COSMIC
COSM7476595 223 COSMIC
COSM9482994 229 COSMIC
COSM3285082 236 COSMIC
COSM9481173 241 COSMIC
COSM3285084 247 COSMIC
COSM460031 257 COSMIC
COSM3285085 280 COSMIC
COSM6565405 282 COSMIC
COSM8531252 282 COSMIC
COSM8223629 291 COSMIC
COSM3285086 296 COSMIC
COSN30308342 310 COSMIC
COSN30460269 346 COSMIC
COSN30209398 364 COSMIC
COSN24388705 375 COSMIC
COSN20270294 593 COSMIC
COSN1761491 634 COSMIC
COSN15835793 743 COSMIC
COSN21728069 887 COSMIC
COSN16616270 1128 COSMIC
COSN17933273 1161 COSMIC
COSN24922703 1179 COSMIC
COSN24765964 1397 COSMIC
COSN7355331 2187 COSMIC
COSN20307709 2489 COSMIC
COSN22188040 2613 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs754630479 2 dbSNP
rs778608744 3 dbSNP
rs113513619 6 dbSNP
rs140072242 8 dbSNP
rs746957344 12 dbSNP
rs770978643 14 dbSNP
rs942528003 15 dbSNP
rs1317031420 16 dbSNP
rs778927554 16 dbSNP
rs143637677 17 dbSNP
rs1332864732 19 dbSNP
rs759382643 21 dbSNP
rs1221528142 35 dbSNP
rs764890433 39 dbSNP
rs1480780410 43 dbSNP
rs976587308 47 dbSNP
rs1385915459 53 dbSNP
rs1298713659 57 dbSNP
rs775811280 58 dbSNP
rs763016140 59 dbSNP
rs978345101 62 dbSNP
rs146780952 63 dbSNP
rs751621465 64 dbSNP
rs376518628 72 dbSNP
rs1488179580 76 dbSNP
rs1189742542 82 dbSNP
rs767985500 84 dbSNP
rs574591326 87 dbSNP
rs149016205 88 dbSNP
rs756526921 89 dbSNP
rs368694270 91 dbSNP
rs1046786350 93 dbSNP
rs569654279 94 dbSNP
rs777484146 100 dbSNP
rs538667480 106 dbSNP
rs771041627 110 dbSNP
rs942293237 113 dbSNP
rs781299366 119 dbSNP
rs558683385 124 dbSNP
rs79307399 125 dbSNP
rs763290772 126 dbSNP
rs1273600377 129 dbSNP
rs768751641 145 dbSNP
rs774459640 147 dbSNP
rs761863491 150 dbSNP
rs1490592545 153 dbSNP
rs767539396 154 dbSNP
rs267605337 162 dbSNP
rs267605338 168 dbSNP
rs535181124 187 dbSNP
rs766781920 188 dbSNP
rs201665040 200 dbSNP
rs1413657457 202 dbSNP
rs1422733637 203 dbSNP
rs1162022997 205 dbSNP
rs758137418 209 dbSNP
rs1424978079 211 dbSNP
rs906651341 213 dbSNP
rs777545288 216 dbSNP
rs1432574218 217 dbSNP
rs11671361 218 dbSNP
rs543074782 220 dbSNP
rs780780047 223 dbSNP
rs141020615 228 dbSNP
rs769602461 230 dbSNP
rs1312485635 234 dbSNP
rs1239762570 235 dbSNP
rs1306273715 237 dbSNP
rs1364355707 241 dbSNP
rs779962217 242 dbSNP
rs1489494432 246 dbSNP
rs749002654 247 dbSNP
rs1018623718 251 dbSNP
rs530446734 252 dbSNP
rs1482595865 257 dbSNP
rs1184105264 258 dbSNP
rs768918294 259 dbSNP
rs1353938723 260 dbSNP
rs1444692214 261 dbSNP
rs1157695665 262 dbSNP
rs1378054578 267 dbSNP
rs774582164 270 dbSNP
rs761986164 277 dbSNP
rs1434539328 278 dbSNP
rs772146277 282 dbSNP
rs1395304653 284 dbSNP
rs1445790012 287 dbSNP
rs1326543889 290 dbSNP
rs769034213 291 dbSNP
rs758587677 294 dbSNP
rs773109765 294 dbSNP
rs1338601735 296 dbSNP
rs1383654537 297 dbSNP
rs1239469807 298 dbSNP
rs1366596129 302 dbSNP
rs748084052 303 dbSNP
rs761304192 303 dbSNP
rs1307355840 304 dbSNP
rs1356052768 308 dbSNP
rs1047666147 309 dbSNP
rs1299868983 310 dbSNP
rs766791847 312 dbSNP
rs1278441877 313 dbSNP
rs148810266 315 dbSNP
rs530589530 317 dbSNP
rs751260273 320 dbSNP
rs1244237639 321 dbSNP
rs1461400476 325 dbSNP
rs944685836 327 dbSNP
rs550445197 329 dbSNP
rs900593468 330 dbSNP
rs1010963113 333 dbSNP
rs1235989603 343 dbSNP
rs1228408340 346 dbSNP
rs1227908107 347 dbSNP
rs1371878820 356 dbSNP
rs1305750072 362 dbSNP
rs1438754882 363 dbSNP
rs141578762 364 dbSNP
rs761748904 370 dbSNP
rs199586141 375 dbSNP
rs1448519511 376 dbSNP
rs372134481 376 dbSNP
rs1395264693 378 dbSNP
rs1194958670 383 dbSNP
rs1055436759 384 dbSNP
rs1430892554 388 dbSNP
rs916847448 393 dbSNP
rs1196883156 394 dbSNP
rs1035228239 408 dbSNP
rs1376380261 411 dbSNP
rs1208453736 413 dbSNP
rs146291620 419 dbSNP
rs1036937541 420 dbSNP
rs528586857 422 dbSNP
rs1272905840 431 dbSNP
rs1204824081 432 dbSNP
rs541172574 457 dbSNP
rs760092881 458 dbSNP
rs1047041423 466 dbSNP
rs906703741 472 dbSNP
rs959739131 476 dbSNP
rs1013878907 478 dbSNP
rs1022599400 482 dbSNP
rs190567880 492 dbSNP
rs973156647 495 dbSNP
rs1305984713 516 dbSNP
rs1165728000 521 dbSNP
rs1428789031 538 dbSNP
rs1052477313 543 dbSNP
rs570422230 549 dbSNP
rs1011335905 560 dbSNP
rs377005112 561 dbSNP
rs1376542940 565 dbSNP
rs1018260465 576 dbSNP
rs1421421400 584 dbSNP
rs1250200391 587 dbSNP
rs911814290 588 dbSNP
rs964327298 593 dbSNP
rs998109446 594 dbSNP
rs1039068527 595 dbSNP
rs182764576 598 dbSNP
rs946814955 604 dbSNP
rs951201506 605 dbSNP
rs1312927598 611 dbSNP
rs982573442 614 dbSNP
rs902716400 627 dbSNP
rs909646216 629 dbSNP
rs753374133 634 dbSNP
rs759136923 646 dbSNP
rs570012960 654 dbSNP
rs1330315240 655 dbSNP
rs915577804 666 dbSNP
rs1012427732 669 dbSNP
rs1158675231 676 dbSNP
rs1023075062 679 dbSNP
rs1410421883 682 dbSNP
rs948340913 683 dbSNP
rs1475778889 695 dbSNP
rs969735011 696 dbSNP
rs764914103 718 dbSNP
rs1185754674 719 dbSNP
rs1027403504 722 dbSNP
rs928182803 728 dbSNP
rs950407923 729 dbSNP
rs1255652071 730 dbSNP
rs375054081 736 dbSNP
rs983290796 737 dbSNP
rs935523180 739 dbSNP
rs1463587759 742 dbSNP
rs1266233415 747 dbSNP
rs1052521638 750 dbSNP
rs893923476 751 dbSNP
rs946804949 753 dbSNP
rs532136843 764 dbSNP
rs1285756809 769 dbSNP
rs1242289758 770 dbSNP
rs911699947 774 dbSNP
rs552211661 791 dbSNP
rs1161725695 792 dbSNP
rs1383476209 792 dbSNP
rs111880494 793 dbSNP
rs1413900378 795 dbSNP
rs1385805128 798 dbSNP
rs751890862 800 dbSNP
rs965970866 806 dbSNP
rs773889 818 dbSNP
rs998560150 821 dbSNP
rs1161830033 826 dbSNP
rs1029587772 828 dbSNP
rs1373911081 834 dbSNP
rs1215908421 844 dbSNP
rs921956285 846 dbSNP
rs1449530283 847 dbSNP
rs1214346875 848 dbSNP
rs1287034371 850 dbSNP
rs1468884873 857 dbSNP
rs1291857855 862 dbSNP
rs1207855851 866 dbSNP
rs946732886 873 dbSNP
rs781535797 876 dbSNP
rs534444547 898 dbSNP
rs548731607 902 dbSNP
rs568546885 907 dbSNP
rs962815460 908 dbSNP
rs117451765 909 dbSNP
rs187055463 928 dbSNP
rs75873352 936 dbSNP
rs539405730 942 dbSNP
rs971087875 947 dbSNP
rs981488651 948 dbSNP
rs928234990 952 dbSNP
rs1397618296 953 dbSNP
rs553095237 955 dbSNP
rs372496965 957 dbSNP
rs75092269 968 dbSNP
rs780143274 981 dbSNP
rs1314471166 989 dbSNP
rs1210836786 991 dbSNP
rs868186567 992 dbSNP
rs1194345000 1008 dbSNP
rs1455600757 1009 dbSNP
rs988294439 1010 dbSNP
rs915408846 1014 dbSNP
rs541973218 1018 dbSNP
rs1450865168 1019 dbSNP
rs1184577739 1023 dbSNP
rs946826334 1033 dbSNP
rs1206975041 1043 dbSNP
rs1039798431 1053 dbSNP
rs899876501 1056 dbSNP
rs934025952 1062 dbSNP
rs994515380 1063 dbSNP
rs1027698907 1067 dbSNP
rs886202249 1069 dbSNP
rs1051080713 1077 dbSNP
rs35287094 1084 dbSNP
rs562242672 1087 dbSNP
rs1004613105 1091 dbSNP
rs887046385 1096 dbSNP
rs965855384 1101 dbSNP
rs1310271936 1115 dbSNP
rs1428145965 1117 dbSNP
rs1004129281 1130 dbSNP
rs1174486241 1131 dbSNP
rs1436739416 1133 dbSNP
rs1416112877 1141 dbSNP
rs1176773785 1144 dbSNP
rs574683133 1145 dbSNP
rs1358065117 1146 dbSNP
rs543682662 1148 dbSNP
rs975100835 1149 dbSNP
rs1028909655 1152 dbSNP
rs1016810191 1161 dbSNP
rs1432368307 1166 dbSNP
rs898333962 1167 dbSNP
rs1309420156 1168 dbSNP
rs139536058 1179 dbSNP
rs1022730110 1182 dbSNP
rs1211115541 1192 dbSNP
rs971523597 1200 dbSNP
rs749402886 1211 dbSNP
rs1218088489 1212 dbSNP
rs1352038585 1223 dbSNP
rs1290693302 1245 dbSNP
rs1408447746 1258 dbSNP
rs935439848 1264 dbSNP
rs532455097 1268 dbSNP
rs981105022 1269 dbSNP
rs1450442479 1270 dbSNP
rs1357598548 1275 dbSNP
rs189919149 1285 dbSNP
rs559103963 1286 dbSNP
rs1031282301 1290 dbSNP
rs992187623 1291 dbSNP
rs956993346 1297 dbSNP
rs1370252194 1321 dbSNP
rs1220314312 1322 dbSNP
rs1412684418 1330 dbSNP
rs988346734 1331 dbSNP
rs780194164 1332 dbSNP
rs1471527549 1348 dbSNP
rs1410938598 1350 dbSNP
rs182404670 1363 dbSNP
rs1188322405 1365 dbSNP
rs60785637 1369 dbSNP
rs1235345758 1380 dbSNP
rs547954214 1381 dbSNP
rs1447056696 1385 dbSNP
rs1270617903 1386 dbSNP
rs968248376 1387 dbSNP
rs1328973602 1390 dbSNP
rs1294302711 1397 dbSNP
rs768978674 1404 dbSNP
rs1377280005 1410 dbSNP
rs921387395 1414 dbSNP
rs934050890 1415 dbSNP
rs1431631822 1418 dbSNP
rs1390923629 1424 dbSNP
rs189074371 1434 dbSNP
rs1051134217 1435 dbSNP
rs908535738 1451 dbSNP
rs1411058275 1455 dbSNP
rs1165258559 1456 dbSNP
rs1191670778 1462 dbSNP
rs1411244588 1466 dbSNP
rs1180889771 1479 dbSNP
rs1424404476 1485 dbSNP
rs931527000 1497 dbSNP
rs1451993154 1521 dbSNP
rs939968634 1531 dbSNP
rs886089485 1532 dbSNP
rs1004663973 1544 dbSNP
rs1224309733 1547 dbSNP
rs193151590 1562 dbSNP
rs1312365856 1564 dbSNP
rs1428690553 1564 dbSNP
rs1215372712 1567 dbSNP
rs1326523855 1568 dbSNP
rs1367550992 1570 dbSNP
rs901718036 1572 dbSNP
rs996029192 1573 dbSNP
rs537236503 1582 dbSNP
rs1437693482 1583 dbSNP
rs1387846136 1584 dbSNP
rs1294017281 1586 dbSNP
rs1029210859 1591 dbSNP
rs1459286188 1596 dbSNP
rs1347896221 1602 dbSNP
rs1163703777 1603 dbSNP
rs550767745 1622 dbSNP
rs968007283 1623 dbSNP
rs184019840 1625 dbSNP
rs898380912 1640 dbSNP
rs146675556 1646 dbSNP
rs1193426217 1647 dbSNP
rs1184120035 1659 dbSNP
rs1298439988 1667 dbSNP
rs1265244697 1674 dbSNP
rs747161487 1675 dbSNP
rs1344621519 1676 dbSNP
rs1012763262 1681 dbSNP
rs10410571 1682 dbSNP
rs918003432 1690 dbSNP
rs969843708 1699 dbSNP
rs553296465 1701 dbSNP
rs1365331160 1711 dbSNP
rs920064276 1726 dbSNP
rs1410158069 1732 dbSNP
rs1372042043 1735 dbSNP
rs1222071993 1740 dbSNP
rs1252230520 1748 dbSNP
rs1428627416 1762 dbSNP
rs563049264 1776 dbSNP
rs1002576952 1779 dbSNP
rs1177536982 1782 dbSNP
rs536176613 1787 dbSNP
rs1031334780 1788 dbSNP
rs1431952640 1794 dbSNP
rs1267226639 1811 dbSNP
rs955714904 1812 dbSNP
rs1467097003 1820 dbSNP
rs144266347 1822 dbSNP
rs535892080 1826 dbSNP
rs1249939601 1834 dbSNP
rs1204695837 1867 dbSNP
rs112114116 1879 dbSNP
rs555572193 1880 dbSNP
rs1231073038 1881 dbSNP
rs1310396591 1883 dbSNP
rs940336461 1890 dbSNP
rs968676090 1892 dbSNP
rs879739279 1896 dbSNP
rs975631729 1917 dbSNP
rs1305863745 1919 dbSNP
rs901603381 1922 dbSNP
rs1402392698 1932 dbSNP
rs8106023 1946 dbSNP
rs1464064929 1947 dbSNP
rs1415535222 1948 dbSNP
rs771963199 1959 dbSNP
rs1473814614 1961 dbSNP
rs986888611 1962 dbSNP
rs1410195410 1969 dbSNP
rs556398157 1970 dbSNP
rs1443217799 1972 dbSNP
rs543595337 1973 dbSNP
rs1198818844 1985 dbSNP
rs1392847331 1987 dbSNP
rs1262510741 1990 dbSNP
rs940019644 1998 dbSNP
rs563498167 2005 dbSNP
rs1228922281 2009 dbSNP
rs1030871190 2017 dbSNP
rs1286234541 2020 dbSNP
rs1437879492 2027 dbSNP
rs577178886 2028 dbSNP
rs545765890 2029 dbSNP
rs569360085 2033 dbSNP
rs1393834357 2041 dbSNP
rs1400866896 2057 dbSNP
rs1321874048 2064 dbSNP
rs1459295572 2065 dbSNP
rs948628840 2069 dbSNP
rs1013548180 2074 dbSNP
rs1473300906 2078 dbSNP
rs1370465664 2080 dbSNP
rs776892089 2080 dbSNP
rs1423382452 2082 dbSNP
rs1248741896 2087 dbSNP
rs559628939 2089 dbSNP
rs1210600522 2090 dbSNP
rs1286138689 2113 dbSNP
rs528069067 2114 dbSNP
rs907024865 2118 dbSNP
rs1466226014 2129 dbSNP
rs1266115064 2130 dbSNP
rs1204387003 2131 dbSNP
rs1228620180 2133 dbSNP
rs1285662232 2138 dbSNP
rs1272306354 2154 dbSNP
rs1381511257 2159 dbSNP
rs1297699501 2161 dbSNP
rs1436593535 2172 dbSNP
rs1002629198 2184 dbSNP
rs1052806958 2185 dbSNP
rs1406354742 2186 dbSNP
rs538335822 2187 dbSNP
rs1011210725 2193 dbSNP
rs558000463 2194 dbSNP
rs1390979121 2197 dbSNP
rs367669456 2199 dbSNP
rs867430497 2204 dbSNP
rs548206511 2206 dbSNP
rs1186853366 2210 dbSNP
rs1361921875 2211 dbSNP
rs1416133114 2215 dbSNP
rs1459189374 2216 dbSNP
rs1160519965 2217 dbSNP
rs1388573408 2218 dbSNP
rs1398959228 2219 dbSNP
rs920137398 2224 dbSNP
rs1336264679 2235 dbSNP
rs1028539724 2237 dbSNP
rs1447572840 2238 dbSNP
rs1291708786 2245 dbSNP
rs1353308779 2247 dbSNP
rs1270193037 2253 dbSNP
rs1437828106 2254 dbSNP
rs1230028673 2256 dbSNP
rs1268641323 2257 dbSNP
rs983071938 2259 dbSNP
rs1322026080 2260 dbSNP
rs1310033666 2261 dbSNP
rs865850258 2261 dbSNP
rs944239326 2261 dbSNP
rs770724829 2263 dbSNP
rs1478318228 2281 dbSNP
rs561586237 2290 dbSNP
rs146587068 2291 dbSNP
rs1015697586 2295 dbSNP
rs139142162 2296 dbSNP
rs1050590014 2298 dbSNP
rs372955775 2300 dbSNP
rs868513881 2301 dbSNP
rs540200234 2303 dbSNP
rs1469044712 2310 dbSNP
rs1174901294 2320 dbSNP
rs1223324738 2323 dbSNP
rs1402963099 2326 dbSNP
rs770793296 2327 dbSNP
rs1408246228 2330 dbSNP
rs919920556 2333 dbSNP
rs948700500 2334 dbSNP
rs1024104357 2337 dbSNP
rs375200188 2338 dbSNP
rs1013432011 2339 dbSNP
rs1412415261 2341 dbSNP
rs1443370709 2345 dbSNP
rs928516775 2353 dbSNP
rs938537652 2362 dbSNP
rs1288762137 2366 dbSNP
rs1481889314 2367 dbSNP
rs1231908211 2368 dbSNP
rs1052855402 2370 dbSNP
rs1335008783 2373 dbSNP
rs111395303 2379 dbSNP
rs891576154 2392 dbSNP
rs1203572923 2403 dbSNP
rs1330356564 2411 dbSNP
rs1002327890 2430 dbSNP
rs376175973 2432 dbSNP
rs1042763080 2434 dbSNP
rs1345078670 2438 dbSNP
rs1209556537 2447 dbSNP
rs1450340725 2453 dbSNP
rs535441290 2456 dbSNP
rs555736819 2457 dbSNP
rs900173232 2468 dbSNP
rs982959037 2477 dbSNP
rs1277698516 2478 dbSNP
rs1483840978 2479 dbSNP
rs552158278 2483 dbSNP
rs1473528315 2486 dbSNP
rs569348517 2488 dbSNP
rs1029009667 2489 dbSNP
rs1465768421 2491 dbSNP
rs538360951 2495 dbSNP
rs1378745890 2496 dbSNP
rs558319674 2512 dbSNP
rs577091922 2513 dbSNP
rs187491435 2518 dbSNP
rs1314501837 2519 dbSNP
rs1435846147 2529 dbSNP
rs965638839 2549 dbSNP
rs552980851 2555 dbSNP
rs1451444258 2558 dbSNP
rs1344372810 2559 dbSNP
rs1182467924 2560 dbSNP
rs1187217553 2560 dbSNP
rs1215219669 2560 dbSNP
rs1250486137 2560 dbSNP
rs1449519887 2560 dbSNP
rs1485776875 2560 dbSNP
rs34083740 2560 dbSNP
rs781377023 2560 dbSNP
rs1247668573 2566 dbSNP
rs976987693 2573 dbSNP
rs922995882 2576 dbSNP
rs931635118 2578 dbSNP
rs1297883866 2579 dbSNP
rs1395465235 2581 dbSNP
rs905698886 2582 dbSNP
rs1325387305 2585 dbSNP
rs1361107247 2588 dbSNP
rs1293925742 2593 dbSNP
rs1438285595 2594 dbSNP
rs1162499124 2609 dbSNP
rs192001589 2615 dbSNP
rs1232855013 2621 dbSNP
rs184068974 2628 dbSNP
rs936396351 2638 dbSNP
rs1428442890 2644 dbSNP
rs542716813 2656 dbSNP
rs76274528 2663 dbSNP
rs1489954265 2671 dbSNP
rs543886558 2673 dbSNP
rs928569583 2676 dbSNP
rs1206124334 2679 dbSNP
rs1484126359 2680 dbSNP
rs1046737708 2695 dbSNP
rs938588023 2701 dbSNP
rs759082077 2702 dbSNP
rs764864876 2708 dbSNP
rs913058684 2711 dbSNP
rs188383572 2748 dbSNP
rs1043200074 2750 dbSNP
rs533354678 2752 dbSNP
rs1220778988 2753 dbSNP
rs1343407210 2776 dbSNP
rs900224796 2778 dbSNP
rs1268589979 2782 dbSNP
rs1371949924 2783 dbSNP
rs547182829 2784 dbSNP
rs567006611 2788 dbSNP
rs1468437002 2790 dbSNP
rs1461027119 2792 dbSNP
rs1378763465 2796 dbSNP
rs113460479 2797 dbSNP
rs1479694940 2814 dbSNP
rs1051413772 2821 dbSNP
rs1183263452 2826 dbSNP
rs891405655 2829 dbSNP
rs888543700 2843 dbSNP
rs1249972699 2850 dbSNP
rs1004278219 2856 dbSNP
rs1169982673 2863 dbSNP
rs1371576867 2864 dbSNP
rs1256586084 2878 dbSNP
rs1205464973 2886 dbSNP
rs1460240176 2893 dbSNP
rs549075680 2898 dbSNP
rs1008483777 2905 dbSNP
rs76847362 2915 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 284434.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714646. RNA binding protein: AGO2. Condition:mildMNase "PAR-CLIP data was present in GSM714647. RNA binding protein: AGO2. Condition:mildMNase ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uuUUCAUUAACACCAAAAa 5'
            |||||| ||||||||| 
Target 5' aaAAGUAACUGUGGUUUUc 3'
 		2 - 20
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714646
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / mildMNase, repA
Location of target site ENST00000524140.2 | 3UTR | AAAAAGUAACUGUGGUUUUCGCCAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714647
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / mildMNase, repB
Location of target site ENST00000524140.2 | 3UTR | AAAAAGUAACUGUGGUUUUCGCCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
168 hsa-miR-548ap-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059371 ANP32E acidic nuclear phosphoprotein 32 family member E 2 2
MIRT072854 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 6
MIRT076951 PCGF2 polycomb group ring finger 2 2 6
MIRT083943 TFAP2C transcription factor AP-2 gamma 2 2
MIRT085407 ETS2 ETS proto-oncogene 2, transcription factor 2 2
MIRT109797 KLHL15 kelch like family member 15 2 2
MIRT114053 AKAP11 A-kinase anchoring protein 11 2 10
MIRT130205 TXNIP thioredoxin interacting protein 2 6
MIRT150038 MIDN midnolin 2 2
MIRT181263 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT205597 NCL nucleolin 2 2
MIRT222256 ACTB actin beta 2 4
MIRT245657 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 4
MIRT250952 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT252500 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT271995 ARF1 ADP ribosylation factor 1 2 4
MIRT280806 RNF11 ring finger protein 11 2 2
MIRT293808 FEM1A fem-1 homolog A 2 2
MIRT318235 RREB1 ras responsive element binding protein 1 2 2
MIRT341461 ATP6V0B ATPase H+ transporting V0 subunit b 2 2
MIRT347424 CEBPG CCAAT/enhancer binding protein gamma 2 4
MIRT351865 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT357988 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT377096 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT407313 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT441565 LMOD3 leiomodin 3 2 2
MIRT442365 ZC3H12C zinc finger CCCH-type containing 12C 2 2
MIRT443229 ARL5B ADP ribosylation factor like GTPase 5B 2 2
MIRT443405 HMX3 H6 family homeobox 3 2 2
MIRT446056 NR5A2 nuclear receptor subfamily 5 group A member 2 2 2
MIRT448278 ZNF652 zinc finger protein 652 2 2
MIRT450823 KCNB1 potassium voltage-gated channel subfamily B member 1 2 2
MIRT453017 CCDC115 coiled-coil domain containing 115 2 17
MIRT454464 PPP2R2B protein phosphatase 2 regulatory subunit Bbeta 2 2
MIRT456361 CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 2 2
MIRT460008 DNALI1 dynein axonemal light intermediate chain 1 2 2
MIRT463155 ZNF385A zinc finger protein 385A 2 6
MIRT463767 YPEL2 yippee like 2 2 2
MIRT468311 SFT2D2 SFT2 domain containing 2 2 2
MIRT470669 POLR2D RNA polymerase II subunit D 2 4
MIRT478518 CTTN cortactin 2 2
MIRT480508 C11orf57 chromosome 11 open reading frame 57 2 2
MIRT484719 INHBA inhibin beta A subunit 2 12
MIRT485495 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT487303 SLC38A9 solute carrier family 38 member 9 2 2
MIRT487772 ANKEF1 ankyrin repeat and EF-hand domain containing 1 2 16
MIRT491877 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT494305 CEP120 centrosomal protein 120 2 2
MIRT495397 TRIM24 tripartite motif containing 24 2 2
MIRT495647 CDK1 cyclin dependent kinase 1 2 2
MIRT496666 TMEM237 transmembrane protein 237 2 2
MIRT496838 ZNF460 zinc finger protein 460 2 2
MIRT498639 CHD4 chromodomain helicase DNA binding protein 4 2 10
MIRT503929 FBXL13 F-box and leucine rich repeat protein 13 2 4
MIRT506064 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT506583 MIER3 MIER family member 3 2 4
MIRT506607 MAT2A methionine adenosyltransferase 2A 2 4
MIRT506845 KIF23 kinesin family member 23 2 6
MIRT508537 RPP14 ribonuclease P/MRP subunit p14 2 4
MIRT509670 ZNF354B zinc finger protein 354B 2 10
MIRT511171 MBNL3 muscleblind like splicing regulator 3 2 6
MIRT512148 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT512832 ID4 inhibitor of DNA binding 4, HLH protein 2 6
MIRT514559 XRCC3 X-ray repair cross complementing 3 2 4
MIRT515857 AJAP1 adherens junctions associated protein 1 2 4
MIRT521849 PNISR PNN interacting serine and arginine rich protein 2 4
MIRT525365 SYNM synemin 2 2
MIRT527121 ARHGAP15 Rho GTPase activating protein 15 2 2
MIRT527272 FBLN2 fibulin 2 2 2
MIRT527440 COL4A3 collagen type IV alpha 3 chain 2 2
MIRT527659 CD300E CD300e molecule 2 2
MIRT528335 TBC1D22B TBC1 domain family member 22B 2 2
MIRT529035 EXOC8 exocyst complex component 8 2 2
MIRT529322 PDE5A phosphodiesterase 5A 2 2
MIRT529678 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT529847 SMTN smoothelin 2 2
MIRT530386 ZNF431 zinc finger protein 431 2 2
MIRT530914 GPR85 G protein-coupled receptor 85 2 2
MIRT531795 KDR kinase insert domain receptor 2 2
MIRT532247 KLF2 Kruppel like factor 2 2 4
MIRT532659 CBX7 chromobox 7 2 2
MIRT533632 TMX3 thioredoxin related transmembrane protein 3 2 2
MIRT534812 RAB33B RAB33B, member RAS oncogene family 2 2
MIRT534976 PSD3 pleckstrin and Sec7 domain containing 3 2 2
MIRT536589 ITPKB inositol-trisphosphate 3-kinase B 2 2
MIRT536780 HNRNPD heterogeneous nuclear ribonucleoprotein D 2 2
MIRT538765 CABLES1 Cdk5 and Abl enzyme substrate 1 2 2
MIRT539296 ANGEL2 angel homolog 2 2 2
MIRT539622 SHISA9 shisa family member 9 2 2
MIRT539652 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT540348 OPHN1 oligophrenin 1 2 2
MIRT540414 PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 2 2
MIRT541397 CDC27 cell division cycle 27 2 2
MIRT542917 HSBP1 heat shock factor binding protein 1 2 2
MIRT544711 EIF5A eukaryotic translation initiation factor 5A 2 4
MIRT544999 MFF mitochondrial fission factor 2 4
MIRT553290 TSPAN3 tetraspanin 3 2 2
MIRT553456 TNRC6C trinucleotide repeat containing 6C 2 2
MIRT553783 TAF13 TATA-box binding protein associated factor 13 2 2
MIRT554657 ROBO1 roundabout guidance receptor 1 2 2
MIRT555105 PURB purine rich element binding protein B 2 2
MIRT557236 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT560862 GAL3ST3 galactose-3-O-sulfotransferase 3 2 2
MIRT561544 SON SON DNA binding protein 2 2
MIRT561555 SLMO2 PRELI domain containing 3B 2 2
MIRT563765 ZNF678 zinc finger protein 678 2 2
MIRT565654 SIX4 SIX homeobox 4 2 2
MIRT568081 CELF2 CUGBP Elav-like family member 2 2 2
MIRT568760 MYBL1 MYB proto-oncogene like 1 2 2
MIRT569079 CADM2 cell adhesion molecule 2 2 2
MIRT569510 THYN1 thymocyte nuclear protein 1 2 2
MIRT571269 CDKN2AIP CDKN2A interacting protein 2 2
MIRT571810 PHF19 PHD finger protein 19 2 2
MIRT572555 DKK3 dickkopf WNT signaling pathway inhibitor 3 2 2
MIRT573783 SLC24A4 solute carrier family 24 member 4 2 4
MIRT576442 Ccdc115 coiled-coil domain containing 115 2 10
MIRT576713 Slc30a3 solute carrier family 30 (zinc transporter), member 3 2 3
MIRT608378 PIWIL2 piwi like RNA-mediated gene silencing 2 2 2
MIRT608485 NKTR natural killer cell triggering receptor 2 6
MIRT610187 FAM49A family with sequence similarity 49 member A 2 2
MIRT611632 EDIL3 EGF like repeats and discoidin domains 3 2 2
MIRT613535 TRA2B transformer 2 beta homolog 2 2
MIRT616222 PTPN11 protein tyrosine phosphatase, non-receptor type 11 2 2
MIRT622371 SALL1 spalt like transcription factor 1 2 2
MIRT624372 CDK12 cyclin dependent kinase 12 2 2
MIRT624996 ZNF665 zinc finger protein 665 2 4
MIRT626876 AP3B1 adaptor related protein complex 3 beta 1 subunit 2 2
MIRT627738 RAP2B RAP2B, member of RAS oncogene family 2 4
MIRT628491 ADAT2 adenosine deaminase, tRNA specific 2 2 2
MIRT633648 PLEKHG7 pleckstrin homology and RhoGEF domain containing G7 2 4
MIRT634029 SLC30A3 solute carrier family 30 member 3 2 3
MIRT635924 GLTSCR2 NOP53 ribosome biogenesis factor 2 2
MIRT638288 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT641960 RNF115 ring finger protein 115 2 2
MIRT643574 CTNNA3 catenin alpha 3 2 2
MIRT645181 NOL9 nucleolar protein 9 2 4
MIRT647498 ZNF639 zinc finger protein 639 2 2
MIRT647683 PCK1 phosphoenolpyruvate carboxykinase 1 2 2
MIRT648423 MYOZ3 myozenin 3 2 2
MIRT650114 ZCCHC9 zinc finger CCHC-type containing 9 2 2
MIRT651077 ZNF518B zinc finger protein 518B 2 4
MIRT651416 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT651457 XKR4 XK related 4 2 2
MIRT653620 SLC30A4 solute carrier family 30 member 4 2 2
MIRT653638 SLC30A1 solute carrier family 30 member 1 2 2
MIRT654897 POU2F1 POU class 2 homeobox 1 2 2
MIRT656484 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT658017 GABRA4 gamma-aminobutyric acid type A receptor alpha4 subunit 2 2
MIRT658042 FZD10 frizzled class receptor 10 2 2
MIRT660094 BTBD3 BTB domain containing 3 2 2
MIRT663924 MAGEF1 MAGE family member F1 2 2
MIRT665883 TGIF2 TGFB induced factor homeobox 2 2 2
MIRT669052 CEP128 centrosomal protein 128 2 2
MIRT669712 AAGAB alpha and gamma adaptin binding protein 2 2
MIRT686813 SNX2 sorting nexin 2 2 4
MIRT689884 SOD2 superoxide dismutase 2 2 2
MIRT693275 GLRX2 glutaredoxin 2 2 4
MIRT697057 BCAR1 BCAR1, Cas family scaffolding protein 2 2
MIRT703298 GID4 GID complex subunit 4 homolog 2 2
MIRT704088 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT707720 CDC6 cell division cycle 6 2 2
MIRT708137 GK5 glycerol kinase 5 (putative) 2 2
MIRT709213 KLHL30 kelch like family member 30 2 2
MIRT710063 RWDD2A RWD domain containing 2A 2 2
MIRT712771 POU6F2 POU class 6 homeobox 2 2 2
MIRT715074 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT715388 TADA3 transcriptional adaptor 3 2 2
MIRT717713 NCKAP1 NCK associated protein 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-548ap Tripterygium wilfordii Hook F resistant tissue
hsa-miR-548ap-3p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-548ap-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-548ap-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)

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