miRTarBase - #MIRT259395


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pre-miRNA Information
pre-miRNA hsa-mir-514b   
Genomic Coordinates chrX: 147250151 - 147250230
Description Homo sapiens miR-514b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-514b-5p
Sequence 13| UUCUCAAGAGGGAGGCAAUCAU |34
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1260150563 12 dbSNP
rs1440758764 15 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SLC6A8   
Synonyms CCDS1, CRT, CRTR, CT1, CTR5
Description solute carrier family 6 member 8
Transcript NM_001142805   
Other Transcripts NM_001142806 , NM_005629   
Expression
Putative miRNA Targets on SLC6A8
3'UTR of SLC6A8
(miRNA target sites are highlighted)		 
>SLC6A8|NM_001142805|3'UTR
   1 CAACTCAGCTCACATCACCAGCTCACCTCTGGTAGCCATAGCAGCCCCTGCTTCAGCCCCACCGCACCCCTCCAGGGGGC
  81 CTGCCTTTCCCTGACACTTTTGGGGTCTGCCTGGGGGAGGAGGGGAGAAAGCACCATGAGTGCTCACTAAAACAACTTTT
 161 TCCATTTTTAATAAAACGCCAAAAATATCACAACCCACCAAAAATAGATGCCTCTCCCCCTCCAGCCCTAGCCGAGCTGG
 241 TCCTAGGCCCCGCCTAGTGCCCCACCCCCACCCACAGTGCTGCACTCCTCCTGCCCCTGCCACGCCCACCCCCTGCCCAC
 321 CTCTCCAGGCTCTGCTCTGCAGCACACCCGTGGGTGACCCCTCACCCCAGAAGCAGCAGTGGCAGCTTGGGAAATGTGAG
 401 GAAGGGAAGGAGGGAGAGACGGGAGGGAGGAGAGAGAGGAGAAGGGAGGCAGGGGAGGGGCAGCAGAACCAAGGCAAATA
 481 TTTCAGCTGGGCTATACCCCTCTCCCCATCCCTGTTATAGAAGCTTAGAGAGCCAGCCAGCAATGGAACCTTCTGGTTCC
 561 TGCGCCAATCGCCACCAGTATCAATTGTGTGAGCTTGGGTGCGAGTGCACGCGTGCGTGAGTACGGAGAGTATATATAGA
 641 TCTCTATCTCTTAGCAAAGGTGAATGCCAGATGTAAATGGCGCCTCTGGGCAAAGGAGGCTTGTATTTTGCACATTTTAT
 721 AAAAACTTGAGAGAATGAGATTTCTGCTTGTATATTTCTAAAAAGAGGAAGGAGCCCAAACCATCCTCTCCTTACCACTC
 801 CCATCCCTGTGAGCCCTACCTTACCCCTCTGCCCCTAGCCAAGGAGTGTGAATTTATAGATCTAACTTTCATAGGCAAAA
 881 CAAAAGCTTCGAGCTGTTGCGTGTGTGAGTCTGTTGTGTGGATGTGCGTGTGTGGTCCCCAGCCCCAGACTGGATTGGAA
 961 AAGTGCATGGTGGGGGCCTCGGGGCTGTCCCCACGCTGTCCCTTTGCCACAAGTCTGTGGGGCAAGAGGCTGCAATATTC
1041 CGTCCTGGGTGTCTGGGCTGCTAACCTGGCCTGCTCAGGCTTCCCACCCTGTGCGGGGCACACCCCCAGGAAGGGACCCT
1121 GGACACGGCTCCCACGTCCAGGCTTAAGGTGGATGCACTTCCCGCACCTCCAGTCTTCTGTGTAGCAGCTTTAACCCACG
1201 TTTGTCTGTCACGTCCAGTCCCGAGACGGCTGAGTGACCCCAAGAAAGGCTTCCCCGACACCCAGACAGAGGCTGCAGGG
1281 CTGGGGCTGGGTGAGGGTGGCGGGCCTGCGGGGACATTCTACTGTGCTAAAAAGCCACTGCAGACATAGCAATAAAAACA
1361 TGTCATTTTCCAAAGCAGGAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uacuAACG---GAGGGA-----GAACUCUu 5'
              ||||   :|:: |     ||||||| 
Target 5' tattTTGCACATTTTATAAAAACTTGAGAg 3'
 704 - 733 142.00 -9.70
2 
miRNA  3' uacuaacggagggaGAACUCUu 5'
                        ||||:|| 
Target 5' agcagcagtggcagCTTGGGAa 3'
 372 - 393 124.00 -10.40
3 
miRNA  3' uacuAACGGA--GGGAGAACUCUu 5'
              || |||  | ||:|||:|: 
Target 5' gcctTTCCCTGACACTTTTGGGGt 3'
 83 - 106 116.00 -13.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
420887 1 ClinVar
1206828 19 ClinVar
68445 1131 ClinVar
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1064794768 1 dbSNP
rs1334295893 1 dbSNP
rs2314080 4 dbSNP
rs1414058321 6 dbSNP
rs782177114 6 dbSNP
rs371155660 7 dbSNP
rs782440074 13 dbSNP
rs782321789 16 dbSNP
rs782159926 19 dbSNP
rs58611639 23 dbSNP
rs781900007 26 dbSNP
rs782546234 36 dbSNP
rs1158205727 39 dbSNP
rs782646311 40 dbSNP
rs782245994 46 dbSNP
rs1370247258 47 dbSNP
rs1188801307 50 dbSNP
rs782363461 51 dbSNP
rs1475144283 55 dbSNP
rs3861555 57 dbSNP
rs1256053010 63 dbSNP
rs1447948440 64 dbSNP
rs3861556 65 dbSNP
rs1284095082 73 dbSNP
rs1202994172 75 dbSNP
rs782695622 78 dbSNP
rs781930842 79 dbSNP
rs1232170287 81 dbSNP
rs1353420049 87 dbSNP
rs1280021602 92 dbSNP
rs3861557 97 dbSNP
rs782077757 98 dbSNP
rs1400608619 106 dbSNP
rs1344370650 111 dbSNP
rs1316019228 112 dbSNP
rs1399146554 114 dbSNP
rs1393188345 115 dbSNP
rs3850325 117 dbSNP
rs1165685148 119 dbSNP
rs1461000716 125 dbSNP
rs1196470059 134 dbSNP
rs1241872781 143 dbSNP
rs1476062193 143 dbSNP
rs1191524014 157 dbSNP
rs1273436582 157 dbSNP
rs1452920844 157 dbSNP
rs1212450402 160 dbSNP
rs1332026870 165 dbSNP
rs1259493293 167 dbSNP
rs1215065607 173 dbSNP
rs1361237610 178 dbSNP
rs1268159910 179 dbSNP
rs1438375092 181 dbSNP
rs1326838727 200 dbSNP
rs1440533582 200 dbSNP
rs1392361570 205 dbSNP
rs782756960 206 dbSNP
rs6571290 208 dbSNP
rs1419448761 213 dbSNP
rs1254092900 216 dbSNP
rs1479209922 216 dbSNP
rs1192603924 227 dbSNP
rs1466896241 234 dbSNP
rs782527490 235 dbSNP
rs1204646075 247 dbSNP
rs1306802363 248 dbSNP
rs1270815452 252 dbSNP
rs1220673770 253 dbSNP
rs1348323594 254 dbSNP
rs1302487428 262 dbSNP
rs1440421226 265 dbSNP
rs1369107756 267 dbSNP
rs1299909544 270 dbSNP
rs1443035835 271 dbSNP
rs1354393494 272 dbSNP
rs1327431758 273 dbSNP
rs1416707822 275 dbSNP
rs1173449959 280 dbSNP
rs1396047607 280 dbSNP
rs1381803587 285 dbSNP
rs1452142177 285 dbSNP
rs1177221828 286 dbSNP
rs1230746998 294 dbSNP
rs1212139108 296 dbSNP
rs1485989130 303 dbSNP
rs1279307477 304 dbSNP
rs1231831733 305 dbSNP
rs60100462 306 dbSNP
rs1224606393 309 dbSNP
rs1309425114 309 dbSNP
rs1372682874 310 dbSNP
rs1417129136 313 dbSNP
rs1376625881 318 dbSNP
rs1312602016 320 dbSNP
rs1433261462 338 dbSNP
rs1361992933 350 dbSNP
rs781904628 351 dbSNP
rs1405136958 355 dbSNP
rs1183140950 360 dbSNP
rs782443363 372 dbSNP
rs1475473505 373 dbSNP
rs1256731165 396 dbSNP
rs1208371363 405 dbSNP
rs1261151550 408 dbSNP
rs1489144307 408 dbSNP
rs1216740503 414 dbSNP
rs1316595098 420 dbSNP
rs1304911810 421 dbSNP
rs1235241492 422 dbSNP
rs782588220 423 dbSNP
rs1293221237 426 dbSNP
rs1413549570 431 dbSNP
rs1364512029 432 dbSNP
rs1289871684 435 dbSNP
rs1452571405 436 dbSNP
rs1343108646 437 dbSNP
rs1166391035 439 dbSNP
rs1461509552 455 dbSNP
rs1416611453 461 dbSNP
rs1185691723 465 dbSNP
rs4532754 472 dbSNP
rs1262126569 476 dbSNP
rs1185747827 482 dbSNP
rs1485637011 496 dbSNP
rs1259200072 500 dbSNP
rs1215566302 505 dbSNP
rs1335545253 509 dbSNP
rs1272688638 512 dbSNP
rs1231978246 516 dbSNP
rs782484566 519 dbSNP
rs1296692832 527 dbSNP
rs1382037207 529 dbSNP
rs1359344839 547 dbSNP
rs1327492129 550 dbSNP
rs1441250401 550 dbSNP
rs2314081 557 dbSNP
rs1393066181 558 dbSNP
rs1162218813 560 dbSNP
rs1463425412 562 dbSNP
rs145908010 564 dbSNP
rs782265181 565 dbSNP
rs1811105 572 dbSNP
rs782048343 574 dbSNP
rs1269284490 576 dbSNP
rs1195719849 585 dbSNP
rs1469115054 586 dbSNP
rs782427829 586 dbSNP
rs781915648 590 dbSNP
rs370387050 594 dbSNP
rs1211940295 596 dbSNP
rs782193905 600 dbSNP
rs1481880622 602 dbSNP
rs4065268 603 dbSNP
rs184055391 604 dbSNP
rs1306110671 606 dbSNP
rs781880445 612 dbSNP
rs374717490 614 dbSNP
rs1369826890 617 dbSNP
rs1392638878 618 dbSNP
rs782525442 618 dbSNP
rs1397043969 625 dbSNP
rs1297534274 626 dbSNP
rs1460456969 627 dbSNP
rs1396639952 628 dbSNP
rs1174075908 629 dbSNP
rs1454845175 631 dbSNP
rs782110853 631 dbSNP
rs1394733551 633 dbSNP
rs1196780263 634 dbSNP
rs1439624128 635 dbSNP
rs1251404162 636 dbSNP
rs1195705839 639 dbSNP
rs1479965795 640 dbSNP
rs1282861600 643 dbSNP
rs1212073359 647 dbSNP
rs1346631216 649 dbSNP
rs1300812091 661 dbSNP
rs1240828742 662 dbSNP
rs1305735238 671 dbSNP
rs782770259 680 dbSNP
rs1377238161 681 dbSNP
rs1313215353 682 dbSNP
rs1433887561 683 dbSNP
rs1373465670 685 dbSNP
rs1171019318 690 dbSNP
rs138494557 692 dbSNP
rs1364422643 698 dbSNP
rs782162541 700 dbSNP
rs1260245244 703 dbSNP
rs782654445 704 dbSNP
rs1189012675 726 dbSNP
rs782703162 728 dbSNP
rs1277021669 729 dbSNP
rs1206505989 733 dbSNP
rs1350998008 734 dbSNP
rs1259591083 736 dbSNP
rs1236286582 737 dbSNP
rs782291584 740 dbSNP
rs3969135 745 dbSNP
rs1414149940 750 dbSNP
rs782687298 751 dbSNP
rs1320089440 753 dbSNP
rs1402624163 757 dbSNP
rs1385974318 764 dbSNP
rs1158007799 766 dbSNP
rs1455715558 796 dbSNP
rs1420196556 798 dbSNP
rs1189253356 799 dbSNP
rs1475196669 810 dbSNP
rs1236057241 812 dbSNP
rs781811746 819 dbSNP
rs1447171148 826 dbSNP
rs1260630052 833 dbSNP
rs782477988 835 dbSNP
rs782750190 836 dbSNP
rs1206211281 840 dbSNP
rs1336279153 847 dbSNP
rs781929482 849 dbSNP
rs1232567297 852 dbSNP
rs200806041 852 dbSNP
rs868994553 853 dbSNP
rs1271664362 854 dbSNP
rs1431216485 862 dbSNP
rs782536193 862 dbSNP
rs1317903014 871 dbSNP
rs1433242639 873 dbSNP
rs1396763088 876 dbSNP
rs1165802228 882 dbSNP
rs1461344895 891 dbSNP
rs782666619 892 dbSNP
rs1475950880 894 dbSNP
rs781783847 901 dbSNP
rs782756300 901 dbSNP
rs3969136 902 dbSNP
rs1253033248 904 dbSNP
rs782448743 906 dbSNP
rs1449737903 907 dbSNP
rs1275030754 909 dbSNP
rs1215158507 910 dbSNP
rs1338490675 913 dbSNP
rs1295194359 915 dbSNP
rs1226420201 917 dbSNP
rs1373510479 924 dbSNP
rs2097220 928 dbSNP
rs1326607537 929 dbSNP
rs1440284205 930 dbSNP
rs1348584029 943 dbSNP
rs1331457451 944 dbSNP
rs34870027 949 dbSNP
rs1411059852 951 dbSNP
rs143048904 954 dbSNP
rs1167130040 956 dbSNP
rs1455265591 957 dbSNP
rs782226707 961 dbSNP
rs782371864 975 dbSNP
rs1192387796 976 dbSNP
rs1476752812 977 dbSNP
rs1234170254 979 dbSNP
rs1205110030 981 dbSNP
rs1437208585 982 dbSNP
rs1272165707 984 dbSNP
rs782650644 984 dbSNP
rs1350256749 995 dbSNP
rs188836948 996 dbSNP
rs1218916063 1006 dbSNP
rs782209157 1010 dbSNP
rs1281399830 1011 dbSNP
rs1443503706 1016 dbSNP
rs782434197 1016 dbSNP
rs1306491297 1022 dbSNP
rs1436985991 1030 dbSNP
rs1376506723 1031 dbSNP
rs535545434 1042 dbSNP
rs367889260 1043 dbSNP
rs1409502633 1057 dbSNP
rs782347855 1057 dbSNP
rs1469527795 1058 dbSNP
rs1249532510 1067 dbSNP
rs1189728916 1070 dbSNP
rs781977609 1074 dbSNP
rs1279421597 1082 dbSNP
rs1209657249 1085 dbSNP
rs1310692332 1095 dbSNP
rs782122554 1095 dbSNP
rs782785061 1096 dbSNP
rs1224414946 1097 dbSNP
rs1350346674 1102 dbSNP
rs1286990397 1104 dbSNP
rs781895441 1116 dbSNP
rs1356469171 1122 dbSNP
rs1302683347 1125 dbSNP
rs1464187287 1127 dbSNP
rs1159111058 1128 dbSNP
rs1399628031 1130 dbSNP
rs13120 1137 dbSNP
rs1166999490 1150 dbSNP
rs782326579 1151 dbSNP
rs1475515103 1155 dbSNP
rs782722002 1161 dbSNP
rs781816375 1164 dbSNP
rs1179934845 1165 dbSNP
rs1803331 1169 dbSNP
rs1482363202 1177 dbSNP
rs782482863 1178 dbSNP
rs1244073778 1181 dbSNP
rs1216849868 1189 dbSNP
rs1328573746 1196 dbSNP
rs1235657912 1197 dbSNP
rs1266360462 1197 dbSNP
rs11548961 1198 dbSNP
rs782632648 1200 dbSNP
rs1394657091 1201 dbSNP
rs781872442 1203 dbSNP
rs1289070434 1209 dbSNP
rs1433987464 1210 dbSNP
rs1385763386 1214 dbSNP
rs781992671 1218 dbSNP
rs1327363898 1223 dbSNP
rs782132040 1224 dbSNP
rs182097343 1228 dbSNP
rs782812004 1229 dbSNP
rs1430071870 1230 dbSNP
rs4898436 1231 dbSNP
rs1187300042 1237 dbSNP
rs1464654051 1238 dbSNP
rs782673650 1242 dbSNP
rs1215668482 1243 dbSNP
rs1469248760 1245 dbSNP
rs782177472 1250 dbSNP
rs1243321573 1257 dbSNP
rs1309625404 1258 dbSNP
rs1227178561 1263 dbSNP
rs1362630278 1266 dbSNP
rs1327256820 1268 dbSNP
rs1441025702 1270 dbSNP
rs1389462491 1279 dbSNP
rs1291714369 1280 dbSNP
rs1463499614 1285 dbSNP
rs1354877384 1286 dbSNP
rs1167753983 1287 dbSNP
rs1449048463 1288 dbSNP
rs1388554705 1290 dbSNP
rs1195513387 1297 dbSNP
rs782323947 1303 dbSNP
rs1266844072 1304 dbSNP
rs782613443 1310 dbSNP
rs1481932896 1311 dbSNP
rs148180779 1317 dbSNP
rs1204902822 1327 dbSNP
rs1339566594 1340 dbSNP
rs187134918 1346 dbSNP
rs1234658069 1360 dbSNP
rs1329971917 1368 dbSNP
rs1298622693 1369 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 6535.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000253122.5 | 3UTR | UAUUUUGCACAUUUUAUAAAAACUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000253122.5 | 3UTR | CAAAGGAGGCUUGUAUUUUGCACAUUUUAUAAAAACUUGAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000253122.5 | 3UTR | UAUUUUGCACAUUUUAUAAAAACUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
THCA -0.312 0.14 -0.284 0.16 14 Click to see details
UCEC -0.898 0.15 -0.500 0.33 3 Click to see details
KIRP 0.251 0.32 0.257 0.31 6 Click to see details
KIRC 0.166 0.36 0.214 0.32 7 Click to see details
KIRC 0.166 0.36 0.214 0.32 7 Click to see details
KIRC 0.166 0.36 0.214 0.32 7 Click to see details
KIRC 0.166 0.36 0.214 0.32 7 Click to see details
KIRC 0.166 0.36 0.214 0.32 7 Click to see details
KIRC 0.166 0.36 0.214 0.32 7 Click to see details
KIRC 0.166 0.36 0.214 0.32 7 Click to see details
101 hsa-miR-514b-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT106072 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT169586 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT259395 SLC6A8 solute carrier family 6 member 8 2 4
MIRT271675 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT286339 PHF12 PHD finger protein 12 2 2
MIRT334478 RPL27A ribosomal protein L27a 2 4
MIRT336467 SRP9 signal recognition particle 9 2 2
MIRT442118 KCNH5 potassium voltage-gated channel subfamily H member 5 2 2
MIRT462291 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT474679 KLF10 Kruppel like factor 10 2 2
MIRT475557 HNRNPF heterogeneous nuclear ribonucleoprotein F 2 2
MIRT479222 CKS2 CDC28 protein kinase regulatory subunit 2 2 2
MIRT496187 TECPR1 tectonin beta-propeller repeat containing 1 2 2
MIRT496811 CHRNB2 cholinergic receptor nicotinic beta 2 subunit 2 2
MIRT506493 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 4
MIRT509595 PEX26 peroxisomal biogenesis factor 26 2 4
MIRT512411 KIAA0391 KIAA0391 2 2
MIRT512439 SFTPB surfactant protein B 2 2
MIRT512581 ZNF223 zinc finger protein 223 2 2
MIRT525990 MAGEL2 MAGE family member L2 2 2
MIRT526427 PARP15 poly(ADP-ribose) polymerase family member 15 2 4
MIRT526772 DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 2 2
MIRT528090 UCHL3 ubiquitin C-terminal hydrolase L3 2 2
MIRT530438 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT532572 GSS glutathione synthetase 2 2
MIRT533990 SUZ12 SUZ12 polycomb repressive complex 2 subunit 2 2
MIRT534782 RAD23B RAD23 homolog B, nucleotide excision repair protein 2 2
MIRT536246 LPP LIM domain containing preferred translocation partner in lipoma 2 2
MIRT536471 KIAA1549L KIAA1549 like 2 2
MIRT538428 COL19A1 collagen type XIX alpha 1 chain 2 2
MIRT538839 BTG3 BTG anti-proliferation factor 3 2 2
MIRT539323 AHSA2 activator of HSP90 ATPase homolog 2 2 4
MIRT547012 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT551817 TMEM138 transmembrane protein 138 2 2
MIRT552910 VPS37A VPS37A, ESCRT-I subunit 2 2
MIRT553169 UBE2G1 ubiquitin conjugating enzyme E2 G1 2 2
MIRT553462 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT553551 TMEM161B transmembrane protein 161B 2 2
MIRT556253 MAPRE2 microtubule associated protein RP/EB family member 2 2 2
MIRT556874 ITGA2 integrin subunit alpha 2 2 2
MIRT558152 ELAVL2 ELAV like RNA binding protein 2 2 2
MIRT560320 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT564022 CEBPB CCAAT/enhancer binding protein beta 2 2
MIRT566386 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT569339 EFHC1 EF-hand domain containing 1 2 2
MIRT572595 PAPLN papilin, proteoglycan like sulfated glycoprotein 2 2
MIRT574178 TMPO thymopoietin 2 2
MIRT610592 NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit 2 2
MIRT615803 COQ7 coenzyme Q7, hydroxylase 2 2
MIRT616714 FEM1B fem-1 homolog B 2 2
MIRT617931 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT620333 SPAST spastin 2 2
MIRT620669 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT620711 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT622709 PLEKHA2 pleckstrin homology domain containing A2 2 2
MIRT623780 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT624111 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT626537 EMCN endomucin 2 2
MIRT630145 ZDHHC9 zinc finger DHHC-type containing 9 2 4
MIRT631638 WDR91 WD repeat domain 91 2 4
MIRT635122 RAD51 RAD51 recombinase 2 2
MIRT637461 DEFB105B defensin beta 105B 2 4
MIRT637493 DEFB105A defensin beta 105A 2 4
MIRT641197 TRIB1 tribbles pseudokinase 1 2 4
MIRT643396 PROM1 prominin 1 2 2
MIRT644889 ZBED1 zinc finger BED-type containing 1 2 2
MIRT647244 PTGDR2 prostaglandin D2 receptor 2 2 2
MIRT647528 CCDC121 coiled-coil domain containing 121 2 2
MIRT648395 WRN Werner syndrome RecQ like helicase 2 2
MIRT650121 G6PC glucose-6-phosphatase catalytic subunit 2 2
MIRT652355 TMEM92 transmembrane protein 92 2 2
MIRT653817 SIM2 single-minded family bHLH transcription factor 2 2 2
MIRT653943 SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 2 2
MIRT657290 HOXB5 homeobox B5 2 2
MIRT657826 GJD3 gap junction protein delta 3 2 2
MIRT658706 EMB embigin 2 2
MIRT658739 ELAVL4 ELAV like RNA binding protein 4 2 2
MIRT660175 BNC2 basonuclin 2 2 2
MIRT661323 TBC1D15 TBC1 domain family member 15 2 2
MIRT662205 PLA2G4E phospholipase A2 group IVE 2 2
MIRT662965 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT663876 CCDC65 coiled-coil domain containing 65 2 2
MIRT671779 RGS17 regulator of G protein signaling 17 2 2
MIRT673644 CYCS cytochrome c, somatic 2 2
MIRT675531 RPL37 ribosomal protein L37 2 2
MIRT676349 KLF8 Kruppel like factor 8 2 2
MIRT678427 PDE4C phosphodiesterase 4C 2 2
MIRT678484 ARHGEF39 Rho guanine nucleotide exchange factor 39 2 2
MIRT690846 PVR poliovirus receptor 2 2
MIRT691991 SGTB small glutamine rich tetratricopeptide repeat containing beta 2 2
MIRT698392 TMED10 transmembrane p24 trafficking protein 10 2 2
MIRT701264 NUP210 nucleoporin 210 2 2
MIRT703553 FKBP14 FK506 binding protein 14 2 2
MIRT711984 EXTL3 exostosin like glycosyltransferase 3 2 2
MIRT712653 PGAP3 post-GPI attachment to proteins 3 2 2
MIRT716759 TRABD2A TraB domain containing 2A 2 2
MIRT717931 ZFP64 ZFP64 zinc finger protein 2 2
MIRT718027 FAM163A family with sequence similarity 163 member A 2 2
MIRT718972 SPTSSA serine palmitoyltransferase small subunit A 2 2
MIRT721650 RPL34 ribosomal protein L34 2 2
MIRT724860 RIMBP2 RIMS binding protein 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-514b Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-miR-514b-5p Platinum 23939 resistant High Ovarian Cancer tissue
hsa-miR-514b-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-514b-5p Cisplatin 5460033 NSC119875 approved resistant Low Colorectal Cancer cell line (LOVO)
hsa-miR-514b-5p Irinotecan 60838 NSC728073 approved resistant Low Colorectal Cancer cell line (LOVO)
hsa-miR-514b-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375)
hsa-miR-514b-5p Tripterygium wilfordii Hook F sensitive tissue
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM43)
hsa-miR-514b-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)

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