miRTarBase - #MIRT261134


—
pre-miRNA Information
pre-miRNA hsa-mir-4477a   
Genomic Coordinates chr9: 41233755 - 41233835
Description Homo sapiens miR-4477a stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4477a
Sequence 48| CUAUUAAGGACAUUUGUGAUUC |69
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1281813060 1 dbSNP
rs1352899679 1 dbSNP
rs1283566158 2 dbSNP
rs1236244724 4 dbSNP
rs75019967 4 dbSNP
rs1348124293 5 dbSNP
rs34026740 8 dbSNP
rs1288237115 9 dbSNP
rs71262206 10 dbSNP
rs1355759977 11 dbSNP
rs1300249508 16 dbSNP
rs1328879592 18 dbSNP
rs139133717 20 dbSNP
Putative Targets

Gene Information
Gene Symbol TRIM8   
Synonyms GERP, RNF27
Description tripartite motif containing 8
Transcript NM_030912   
Expression
Putative miRNA Targets on TRIM8
3'UTR of TRIM8
(miRNA target sites are highlighted)		 
>TRIM8|NM_030912|3'UTR
   1 CGCCACGCAGGCGGCGGGGCGCTGGGGAATCTTCCTCCCCAGCCCCCGGGCTCGGGAGTTATGCATCCAGAGACCTGCCC
  81 TTCTACCTTCCTCGCCTCCCCTCTTCCTCATTCCATTGCCCCAGGTCTTTTCCTTTTGGATTTTGTTTTGGTTTTGGCTT
 161 TGTTTTTGATTTTTTTTTATTATGAATCTCCTGGACGCAGAGGTGACAGTGGGAGCTGGCCTGGGCCAGGACGGCAGGTG
 241 GCCCTGGAGATGGGAAAGTGTCTGTGTCGAGGCGCTGAGCTCTCTCTCTGTTTCTCCTTTTTTCCTCTACTCCTTCCCCT
 321 TCACACCCCCGTGGCTGGAAGGAACCTCGGCTTCCCTGAAAGCTTGGGGGTCCCACCCTTCTTACCCCACCCGGGAGGAA
 401 CGCCCAGGGCCCCGGGCTTGTTTCTCCTCTTGTTTTCCTTTTGGGCAGTTTGATCACTGATCGAGTAAGGAATGACCTTT
 481 AGATTGTGCGACTTTTGTTTTTGTTTTTTTAAATTTTTTTAAACCAAGAATGATTTCTCCTGCTTCCTTCTCCTCACCAT
 561 CTTCCCAGACGGAGTTCAAAGGCCACTTCTCAAGCAGCTTTTGGCACCTTCAGCCTCAGAGTGGAATCTTTTAAAGACAG
 641 GACCCCTATGTCCAGGAAAGGGGAAAAGGAACTTTGCCAATGATAGTGACCACAGCAAAAGCAAATAATAATAATATTAA
 721 TAATAATAAAGAGAAATAAAATAATAAAATAAAAAACAATAGCACAGCCCTTGTTGAGGTCAGCAGGGAGGAGGGGCTGC
 801 CCGGAGTTGGGTCCTTGCCTGGATTTTGACACAGCAACTTCCTGTAGTGAGCACTTTGTATGAATCGTGGACTTCCTGTT
 881 CTCAAGGCGCAGGTATTTATTCTGTATCTGTCTAGAGCACACACCAAAATCCAACCTTCTAATAAACATGATGGCGCAGT
 961 CCCACAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuuaguguuuACAGGAAUUAuc 5'
                    |||::||:||  
Target 5' gttttggcttTGTTTTTGATtt 3'
 151 - 172 104.00 -5.70
2 
miRNA  3' cuUAGUGUUUACAGGAAUUAUc 5'
            :| | :|||| |||| | | 
Target 5' gaGTAAGGAATGACCTTTAGAt 3'
 463 - 484 104.00 -9.10
3 
miRNA  3' cuuaGUGU--UUACAGGA-AUUAUc 5'
              ||||  ||  |||| ||:|: 
Target 5' ttgaCACAGCAACTTCCTGTAGTGa 3'
 826 - 850 100.00 -8.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN27000047 3 COSMIC
COSN511292 12 COSMIC
COSN31562314 21 COSMIC
COSN27000045 27 COSMIC
COSN30486159 39 COSMIC
COSN30486146 40 COSMIC
COSN30116525 43 COSMIC
COSN25596569 63 COSMIC
COSN30119138 64 COSMIC
COSN28843920 179 COSMIC
COSN28149626 180 COSMIC
COSN5246293 188 COSMIC
COSN24565345 310 COSMIC
COSN31960540 490 COSMIC
COSN31570870 538 COSMIC
COSN26643111 615 COSMIC
COSN30539306 618 COSMIC
COSN21934367 789 COSMIC
COSN8525582 803 COSMIC
COSN23045331 903 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs201289362 2 dbSNP
rs899209934 3 dbSNP
rs1365098197 5 dbSNP
rs367683068 6 dbSNP
rs572174183 7 dbSNP
rs759110071 8 dbSNP
rs1359554057 9 dbSNP
rs775319414 10 dbSNP
rs921318012 12 dbSNP
rs1029374130 13 dbSNP
rs762898690 13 dbSNP
rs763917208 13 dbSNP
rs545802670 14 dbSNP
rs751122356 15 dbSNP
rs1197029889 16 dbSNP
rs374915046 16 dbSNP
rs751338987 17 dbSNP
rs1217208925 18 dbSNP
rs761405827 19 dbSNP
rs528722602 20 dbSNP
rs767767471 21 dbSNP
rs1219727320 22 dbSNP
rs780028179 23 dbSNP
rs558014342 25 dbSNP
rs1256911822 27 dbSNP
rs372264167 28 dbSNP
rs1030857250 29 dbSNP
rs1405581138 30 dbSNP
rs754298290 32 dbSNP
rs1232076900 34 dbSNP
rs770056409 34 dbSNP
rs575991102 35 dbSNP
rs779334132 36 dbSNP
rs748529550 38 dbSNP
rs945639289 39 dbSNP
rs1332150817 41 dbSNP
rs201074269 46 dbSNP
rs1404189553 47 dbSNP
rs1366457173 48 dbSNP
rs375140175 49 dbSNP
rs769379402 50 dbSNP
rs775170274 51 dbSNP
rs561494166 54 dbSNP
rs868663721 59 dbSNP
rs528960543 63 dbSNP
rs1054748495 65 dbSNP
rs1458765147 67 dbSNP
rs113928559 70 dbSNP
rs980477728 72 dbSNP
rs540686336 78 dbSNP
rs560334590 81 dbSNP
rs1199571466 86 dbSNP
rs1340521905 92 dbSNP
rs1398703600 94 dbSNP
rs995036922 99 dbSNP
rs1027483538 100 dbSNP
rs927597430 101 dbSNP
rs1004719502 102 dbSNP
rs938972531 106 dbSNP
rs1313175354 107 dbSNP
rs993477308 110 dbSNP
rs965963067 111 dbSNP
rs1396865657 114 dbSNP
rs1404563643 115 dbSNP
rs1255093470 118 dbSNP
rs565890839 121 dbSNP
rs940857868 132 dbSNP
rs1037792669 133 dbSNP
rs1487642085 134 dbSNP
rs899262334 149 dbSNP
rs1240772771 164 dbSNP
rs397955454 170 dbSNP
rs59879602 170 dbSNP
rs1028764849 177 dbSNP
rs954152168 179 dbSNP
rs1270903591 180 dbSNP
rs990003848 184 dbSNP
rs932029448 185 dbSNP
rs1243012311 191 dbSNP
rs1357882077 196 dbSNP
rs1376192052 198 dbSNP
rs528398349 201 dbSNP
rs1283704228 213 dbSNP
rs915335618 216 dbSNP
rs1050467536 217 dbSNP
rs890434261 233 dbSNP
rs1316585274 234 dbSNP
rs748000726 238 dbSNP
rs1008850433 249 dbSNP
rs966827697 263 dbSNP
rs1031333645 264 dbSNP
rs892349426 269 dbSNP
rs1421478145 274 dbSNP
rs551429294 275 dbSNP
rs773438873 280 dbSNP
rs928207046 280 dbSNP
rs1022109640 282 dbSNP
rs1190645238 283 dbSNP
rs527862605 284 dbSNP
rs1219195591 288 dbSNP
rs1264397057 288 dbSNP
rs1490008833 289 dbSNP
rs552629072 291 dbSNP
rs1210956066 295 dbSNP
rs1002345041 296 dbSNP
rs571115826 298 dbSNP
rs1268470267 300 dbSNP
rs1034723331 306 dbSNP
rs1341321664 310 dbSNP
rs1278636420 318 dbSNP
rs960641992 327 dbSNP
rs58774783 330 dbSNP
rs908135450 331 dbSNP
rs1049250651 332 dbSNP
rs550199737 335 dbSNP
rs1299637797 337 dbSNP
rs886206890 342 dbSNP
rs760347036 346 dbSNP
rs1040258095 350 dbSNP
rs1196313681 355 dbSNP
rs1241889476 356 dbSNP
rs1479700607 357 dbSNP
rs962234279 365 dbSNP
rs1223009351 366 dbSNP
rs568421753 366 dbSNP
rs1453806648 367 dbSNP
rs996134505 370 dbSNP
rs766019022 371 dbSNP
rs1318894511 384 dbSNP
rs1260159995 387 dbSNP
rs186255685 387 dbSNP
rs932108809 388 dbSNP
rs1274001821 389 dbSNP
rs1213782045 391 dbSNP
rs1332715414 407 dbSNP
rs879906547 407 dbSNP
rs1464595526 412 dbSNP
rs1400387949 413 dbSNP
rs1267196440 414 dbSNP
rs1172447877 422 dbSNP
rs1488757643 424 dbSNP
rs1190476962 425 dbSNP
rs1192103193 427 dbSNP
rs1479305323 428 dbSNP
rs1231616128 437 dbSNP
rs1178107775 438 dbSNP
rs1458324018 441 dbSNP
rs1022774050 448 dbSNP
rs966795103 459 dbSNP
rs1265008428 463 dbSNP
rs150392107 464 dbSNP
rs1050927180 466 dbSNP
rs911936403 467 dbSNP
rs944707701 471 dbSNP
rs1306901010 489 dbSNP
rs1052401753 490 dbSNP
rs1332754721 493 dbSNP
rs1445404369 494 dbSNP
rs1358171185 498 dbSNP
rs1177268706 500 dbSNP
rs11550358 504 dbSNP
rs1165525494 506 dbSNP
rs1158630351 508 dbSNP
rs1440820503 511 dbSNP
rs1240143687 512 dbSNP
rs1351035253 513 dbSNP
rs1180150987 514 dbSNP
rs1483060006 514 dbSNP
rs60609009 514 dbSNP
rs116740892 515 dbSNP
rs1210562367 521 dbSNP
rs1292232096 525 dbSNP
rs1443986630 534 dbSNP
rs1399107896 547 dbSNP
rs1447930962 550 dbSNP
rs991446431 553 dbSNP
rs1354279752 554 dbSNP
rs191156076 559 dbSNP
rs1375661304 570 dbSNP
rs557807779 571 dbSNP
rs776010249 578 dbSNP
rs1303139012 583 dbSNP
rs1043605022 585 dbSNP
rs1359078755 592 dbSNP
rs879399903 607 dbSNP
rs369818961 620 dbSNP
rs1001995789 629 dbSNP
rs1263558872 637 dbSNP
rs1035177814 647 dbSNP
rs1423249439 647 dbSNP
rs1458949825 657 dbSNP
rs907601293 673 dbSNP
rs1183869038 681 dbSNP
rs1199011289 682 dbSNP
rs1260804714 687 dbSNP
rs1215566860 693 dbSNP
rs1262352372 704 dbSNP
rs1488587042 704 dbSNP
rs531707518 706 dbSNP
rs1219279725 709 dbSNP
rs774651991 711 dbSNP
rs1040228629 712 dbSNP
rs1229712879 715 dbSNP
rs901711182 715 dbSNP
rs1363009997 718 dbSNP
rs1400932023 718 dbSNP
rs201685765 718 dbSNP
rs1292359396 719 dbSNP
rs1423265939 721 dbSNP
rs759029126 725 dbSNP
rs1375254644 731 dbSNP
rs1192677128 734 dbSNP
rs1478065252 734 dbSNP
rs536900556 734 dbSNP
rs893066046 738 dbSNP
rs766735590 743 dbSNP
rs962288126 744 dbSNP
rs973606676 745 dbSNP
rs1265543142 749 dbSNP
rs1399177745 751 dbSNP
rs1444132955 757 dbSNP
rs71471248 757 dbSNP
rs1256953947 762 dbSNP
rs920790837 764 dbSNP
rs953669039 771 dbSNP
rs1342838716 786 dbSNP
rs1299607429 791 dbSNP
rs1011311479 799 dbSNP
rs1022319757 800 dbSNP
rs966763991 803 dbSNP
rs764569751 804 dbSNP
rs182250999 807 dbSNP
rs1035076453 810 dbSNP
rs1310541107 811 dbSNP
rs1267901303 814 dbSNP
rs944780943 824 dbSNP
rs573272467 842 dbSNP
rs540754406 847 dbSNP
rs1456116108 857 dbSNP
rs1319890270 867 dbSNP
rs1219077417 875 dbSNP
rs1052455663 877 dbSNP
rs1232919135 882 dbSNP
rs913887984 883 dbSNP
rs1456233508 887 dbSNP
rs1212534889 889 dbSNP
rs946647572 890 dbSNP
rs559383397 894 dbSNP
rs572592724 896 dbSNP
rs1482987767 903 dbSNP
rs571565293 910 dbSNP
rs752108881 911 dbSNP
rs905061929 919 dbSNP
rs1024275691 920 dbSNP
rs757744005 925 dbSNP
rs952356508 940 dbSNP
rs1300875268 942 dbSNP
rs375492703 955 dbSNP
rs546371618 956 dbSNP
rs564473956 957 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 81603.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000302424.7 | 3UTR | CAAAUAAUAAUAAUAUUAAUAAUAAUAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
134 hsa-miR-4477a Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055843 PLEKHA1 pleckstrin homology domain containing A1 2 10
MIRT061259 AMOTL1 angiomotin like 1 2 4
MIRT071895 BTF3L4 basic transcription factor 3 like 4 2 6
MIRT076933 MLLT6 MLLT6, PHD finger containing 2 2
MIRT078652 ICT1 mitochondrial ribosomal protein L58 2 2
MIRT083633 PRNP prion protein 2 2
MIRT091629 RPL15 ribosomal protein L15 2 4
MIRT107076 PPP6C protein phosphatase 6 catalytic subunit 2 2
MIRT111191 TRIM33 tripartite motif containing 33 2 2
MIRT114515 ARF6 ADP ribosylation factor 6 2 2
MIRT175250 PSAT1 phosphoserine aminotransferase 1 2 4
MIRT175430 ACSL4 acyl-CoA synthetase long chain family member 4 2 2
MIRT178687 FAM102B family with sequence similarity 102 member B 2 2
MIRT189771 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT229450 RPL10 ribosomal protein L10 2 2
MIRT244899 PHF6 PHD finger protein 6 2 2
MIRT249189 AKIRIN1 akirin 1 2 8
MIRT261134 TRIM8 tripartite motif containing 8 2 2
MIRT275561 ZIC5 Zic family member 5 2 4
MIRT275652 ABHD13 abhydrolase domain containing 13 2 2
MIRT288082 UTP18 UTP18, small subunit processome component 2 2
MIRT303605 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT307924 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT316787 FOXC1 forkhead box C1 2 2
MIRT326910 SCML2 Scm polycomb group protein like 2 2 2
MIRT327713 SPIN4 spindlin family member 4 2 2
MIRT331632 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 2
MIRT342506 TMOD3 tropomodulin 3 2 4
MIRT354470 LRRC58 leucine rich repeat containing 58 2 2
MIRT378711 TRIM24 tripartite motif containing 24 2 2
MIRT407462 YDJC YdjC chitooligosaccharide deacetylase homolog 2 2
MIRT408226 SMAD5 SMAD family member 5 2 4
MIRT441824 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT442783 CHD8 chromodomain helicase DNA binding protein 8 2 2
MIRT443184 NHS NHS actin remodeling regulator 2 4
MIRT447615 CUL3 cullin 3 2 2
MIRT450156 DSEL dermatan sulfate epimerase-like 2 2
MIRT454801 NEDD9 neural precursor cell expressed, developmentally down-regulated 9 2 2
MIRT463050 ZNF644 zinc finger protein 644 2 2
MIRT467400 SOCS3 suppressor of cytokine signaling 3 2 2
MIRT468174 SGMS1 sphingomyelin synthase 1 2 2
MIRT468949 RPS14 ribosomal protein S14 2 6
MIRT469835 R3HDM4 R3H domain containing 4 2 2
MIRT470724 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT470902 PLIN3 perilipin 3 2 2
MIRT472467 NAPG NSF attachment protein gamma 2 12
MIRT472602 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT492350 SEMA7A semaphorin 7A (John Milton Hagen blood group) 2 2
MIRT493840 FOXN3 forkhead box N3 2 4
MIRT496318 DOCK9 dedicator of cytokinesis 9 2 2
MIRT500159 CLEC2D C-type lectin domain family 2 member D 2 8
MIRT500535 XPO4 exportin 4 2 4
MIRT503916 FBXL13 F-box and leucine rich repeat protein 13 2 4
MIRT504003 SAT1 spermidine/spermine N1-acetyltransferase 1 2 4
MIRT505647 SHMT1 serine hydroxymethyltransferase 1 2 4
MIRT506574 MIER3 MIER family member 3 2 4
MIRT506945 HS3ST3B1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 2 4
MIRT508196 RPS19 ribosomal protein S19 2 6
MIRT511417 HSPA13 heat shock protein family A (Hsp70) member 13 2 4
MIRT512326 ACTB actin beta 2 4
MIRT515376 RPL7 ribosomal protein L7 2 2
MIRT520422 TUBG1 tubulin gamma 1 2 4
MIRT524844 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT526320 UGT2A1 UDP glucuronosyltransferase family 2 member A1 complex locus 2 2
MIRT526561 UGT2A2 UDP glucuronosyltransferase family 2 member A2 2 2
MIRT528027 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT529874 RBM43 RNA binding motif protein 43 2 2
MIRT530826 CLEC4D C-type lectin domain family 4 member D 2 2
MIRT531334 GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 2 2
MIRT532068 CCNB1 cyclin B1 2 4
MIRT532870 ZNF566 zinc finger protein 566 2 2
MIRT535580 NUP35 nucleoporin 35 2 2
MIRT537644 ERGIC2 ERGIC and golgi 2 2 4
MIRT537725 ELAVL2 ELAV like RNA binding protein 2 2 2
MIRT538894 BRI3BP BRI3 binding protein 2 2
MIRT538945 BMP2K BMP2 inducible kinase 2 2
MIRT540703 PDPK1 3-phosphoinositide dependent protein kinase 1 2 4
MIRT543210 TMEM117 transmembrane protein 117 2 3
MIRT543357 LYRM2 LYR motif containing 2 2 2
MIRT544905 CLSPN claspin 2 2
MIRT545532 ARF3 ADP ribosylation factor 3 2 2
MIRT546446 SMOC1 SPARC related modular calcium binding 1 2 2
MIRT546882 PURB purine rich element binding protein B 2 4
MIRT547440 MED13 mediator complex subunit 13 2 2
MIRT548027 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548673 CRNKL1 crooked neck pre-mRNA splicing factor 1 2 2
MIRT550435 LLGL2 LLGL2, scribble cell polarity complex component 2 2
MIRT551850 RPS3 ribosomal protein S3 2 2
MIRT556072 MRFAP1 Morf4 family associated protein 1 2 2
MIRT556554 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT557132 HOXA13 homeobox A13 2 2
MIRT557875 FEM1B fem-1 homolog B 2 4
MIRT558146 ELK4 ELK4, ETS transcription factor 2 2
MIRT558862 CD2AP CD2 associated protein 2 2
MIRT558884 CCNE1 cyclin E1 2 4
MIRT558907 CBX5 chromobox 5 2 2
MIRT559175 BRAP BRCA1 associated protein 2 2
MIRT560860 GAL3ST3 galactose-3-O-sulfotransferase 3 2 2
MIRT561729 PPIF peptidylprolyl isomerase F 2 2
MIRT564024 CEBPB CCAAT/enhancer binding protein beta 2 2
MIRT564366 TRMT5 tRNA methyltransferase 5 2 2
MIRT564609 ZNF703 zinc finger protein 703 2 2
MIRT565494 AZF1 azoospermia factor 1 2 2
MIRT565577 SLC6A8 solute carrier family 6 member 8 2 2
MIRT566947 LEPROT leptin receptor overlapping transcript 2 2
MIRT567293 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2 2
MIRT567308 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT568048 CHSY1 chondroitin sulfate synthase 1 2 2
MIRT571807 PHF19 PHD finger protein 19 2 2
MIRT609234 RBM23 RNA binding motif protein 23 2 2
MIRT610328 SSX5 SSX family member 5 2 2
MIRT611428 UGT8 UDP glycosyltransferase 8 2 4
MIRT611709 SLFN13 schlafen family member 13 2 2
MIRT612069 CEP135 centrosomal protein 135 2 4
MIRT617676 JRKL JRK like 2 2
MIRT623684 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT635634 PRR15L proline rich 15 like 2 2
MIRT636422 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT637011 GPATCH11 G-patch domain containing 11 2 2
MIRT644150 C4orf3 chromosome 4 open reading frame 3 2 2
MIRT648562 MEMO1 mediator of cell motility 1 2 2
MIRT650752 WNT16 Wnt family member 16 2 2
MIRT651914 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT653556 SLC38A7 solute carrier family 38 member 7 2 2
MIRT692277 XRN2 5'-3' exoribonuclease 2 2 2
MIRT697650 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT703876 ERCC6 ERCC excision repair 6, chromatin remodeling factor 2 2
MIRT704615 CLIP1 CAP-Gly domain containing linker protein 1 2 2
MIRT708562 BBOX1 gamma-butyrobetaine hydroxylase 1 2 2
MIRT709614 KBTBD6 kelch repeat and BTB domain containing 6 2 2
MIRT712955 SGCD sarcoglycan delta 2 2
MIRT713502 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT720239 GPBP1 GC-rich promoter binding protein 1 2 2
MIRT724255 GLUD1 glutamate dehydrogenase 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4477a Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-4477a Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-4477a Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)

Error report submission