miRTarBase - #MIRT266815


—
pre-miRNA Information
pre-miRNA hsa-mir-4476   
Genomic Coordinates chr9: 36893462 - 36893531
Description Homo sapiens miR-4476 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4476
Sequence 45| CAGGAAGGAUUUAGGGACAGGC |66
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 6 9 - 36893482 29233923 MiREDiBase
A-to-I 9 9 - 36893479 29233923 MiREDiBase
A-to-I 13 9 - 36893475 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs978640498 3 dbSNP
rs1019792440 6 dbSNP
rs1008364367 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SLC25A44   
Synonyms -
Description solute carrier family 25 member 44
Transcript NM_014655   
Expression
Putative miRNA Targets on SLC25A44
3'UTR of SLC25A44
(miRNA target sites are highlighted)		 
>SLC25A44|NM_014655|3'UTR
   1 CCAGTGGTGGGGAGAGAAGCCTGCTGTTTTCCACACTACCGTGGGTCAGGGGCAGAGTGGAGAGGACAGCACCCTCTCCA
  81 GGTGCTCCCACCACACACCCAGCCCTGCCCTGGGCCAAGTGGCCTATCTGGGATAGGGATAGAGACTTTGAACTGCTCTT
 161 GCTGAAGAGGCTCCACGCCTGGATCCCTTGCCCCCACTATTTAAAATTCTCTTCTGAGCTGGGCTCCCTCACTCAGTCCC
 241 TGTATTTGATACTGGCCTAAAGACCCCACCCCCCACCCTGCCAGCCCTTCTTCTGGCTTCCCCTTCCATCTGTGTCCCTG
 321 AGACCCTGAGAAGAGCTGTACATAGAGCTTGCTTACTACCACTGGTTCTTCCTCTTGGGCTTTCAGCCCAGACTCCAAGC
 401 AGCTGCTATCAACCCTCTCTCCCTTCATCTCTTAGCCTTGCTTATTTTTATTTTGGGACCGAGCTGCCCACTAGATGACT
 481 CTGCTTTTCCCTGCATTTGGGGCTAAGGTGCCAGGTACTTATTTGCACAGGGAGCAGGAGCAGCAAAAAATCTCTGGTTC
 561 TCCAGAGCACTCGTCCTCTCTTTGGAGGGGTTATTAGGTTGGGAGAAATGTTGATACTTTTGTTTTGTGTGTGTGTGTGT
 641 GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTAACATCTGTGAACCAGGCTATTAGTCCTGCTAAAGCGCCAATCCTGC
 721 TGTCAGAGCTCACCCCCTTCCTAAGACAGGTAGAAAAATGTAATGTAGCTTTTTCCACAAGCCACTTCCCTGTCCCTTCA
 801 GTCTCAGGAGCCCTAGGAGAGTCTAAGCTGGGGCATCCCCTGGCCCAGAGGACTCCCGTGGTGGGCACAGTTCTAAGTGG
 881 ATCAGGCTGTCTTGGGTGCACTGGACTTGGAGCACTACCTTGAGAAGTCAGGTTGAGAAAGTAGTTGATCTAGAAGGCAA
 961 CAAGTGGGCATGTGTTCCCCAGCACATTACCCAGGCCAGCAGAGCCAAACCTAGGAGAGGGCAGTGGGTAGATTCTCTGC
1041 CCCAGGCAGCCATGACATACACATAAATACCCCAATCACTCAGACTTACGGCAACAAGTGTTGTCTCACTATGGTGATCT
1121 CTAAGATCCACATCACTGGATGCGTAGTCATCCCAGTCATGGTACCCTGTGGAGGAATGCTGGAAGAACATAAAGAGCAG
1201 TTCAGAAAGTCACCCAATACCAGGACCACTGCATTTACCAGCCTGATACTGCCAAGATTATCTGATGCTCTCCTCAGGAG
1281 CTAGGAGAGGAGTGCTCCTTCCTCCCTACCGCTACTCTCCCCAAGCCTGTGTTGCAGGTAGAGAGGTGCAGCAAATAGAG
1361 AAGGCATGTCAAACCCTGCATTTCTACCTGAGACGTGTGACCTGGATGATCCTCCAAACCCTATTGGTCCCACCCCCTGG
1441 GAAAGGCCATGGTGCCAGTTTGAAAGGTGCTAGCTACCTGAAGCCTTGATATTTCTTCATGGCTGCCGCACATTCTTCCA
1521 CCTTGGCCAGAACAGGTTCTGAAAACCACTTCTCTACCTTCACCACCACCACTGCCCATCTTGATCTCTTTGAGGGTTTT
1601 CCCATTTCACTTGATCTTATTTTTGTTTATCCCTTCCTGCACTTTGTCAAGAGAGTCCTCCAGTTTCTATCCAGGAATGT
1681 TCACATCCAAAGGGTTGGACCCACGGATCATTCTGAATCTTCCTGCCCCTCCTCACTGCTTAACCCTGAGAACCACAAAT
1761 ATAATGGAAGCAGTTCCCCCCACCCTCACCCCATCTCTTTAAGCTCATCCTAGCAAGACCTCTAGAGACCCTAGAGACTC
1841 GACTTTAGTCCTTCCCCGCCATGGCACAGTGGGGAAGGTGTCAATGGGGAGTGTCACGGACAGGAGGTAGGATCCTGCCG
1921 CTCGCGTCTTAGTGTTTCTCCCTCAAGACTTTCCTTCTGTTTTGTTGTCTTGTGCAGTATTTTACAGCCCCTCTTGTGTT
2001 TTTCTTTATTTCTCGTACACACACGCAGTTTTAAGGGTGATGTGTGTATAATTAAAAGGACCCTTGGCCCATACTTTCCT
2081 AATTCTTTAGGGACTGGGATTGGGTTTGACTGAAATATGTTTTGGTGGGGATGGGACGGTGGACTTCCATTCTCCCTAAA
2161 CTGGAGTTTTGGTCGGTAATCAAAACTAAAAGAAACCTCTGGGAGACTGGAAACCTGATTGGAGCACTGAGGAACAAGGG
2241 AATGAAAAGGCAGACTCTCTGAACGTTTGATGAAATGGACTCTTGTGAAAATTAACAGTGAATATTCACTGTTGCACTGT
2321 ACGAAGTCTCTGAAATGTAATTAAAAGTTTTTATTGAGCCCCCGAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgGACAGGGA-UUUAGGAAGGAc 5'
            :| ||||| ||: |:||||| 
Target 5' gtTTCTCCCTCAAGACTTTCCTt 3'
 1934 - 1956 152.00 -16.30
2 
miRNA  3' cgGACAG----GGAUUUAGGAAGGAc 5'
            |||||    |: |   ||||||| 
Target 5' tgCTGTCAGAGCTCACCCCCTTCCTa 3'
 718 - 743 150.00 -15.20
3 
miRNA  3' cgGACAGGGAUUUAGGAAGGAc 5'
            :| |: :| |  ||||||| 
Target 5' taTTTTTGTTTATCCCTTCCTg 3'
 1618 - 1639 148.00 -15.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31595362 11 COSMIC
COSN30165042 65 COSMIC
COSN31597995 70 COSMIC
COSN23013974 79 COSMIC
COSN16726349 116 COSMIC
COSN30149905 125 COSMIC
COSN30532738 139 COSMIC
COSN31567280 178 COSMIC
COSN20714393 352 COSMIC
COSN22592645 385 COSMIC
COSN30544825 574 COSMIC
COSN26575262 587 COSMIC
COSN30540440 593 COSMIC
COSN18723612 670 COSMIC
COSN27204983 671 COSMIC
COSN27959134 700 COSMIC
COSN31565099 758 COSMIC
COSN26634394 786 COSMIC
COSN30175976 859 COSMIC
COSN31778074 1145 COSMIC
COSN30174335 1276 COSMIC
COSN28702730 1309 COSMIC
COSN31572410 1311 COSMIC
COSN22635796 1343 COSMIC
COSN5732246 1349 COSMIC
COSN20095434 1395 COSMIC
COSN9363865 1422 COSMIC
COSN31577306 1429 COSMIC
COSN7178785 1508 COSMIC
COSN24298059 1546 COSMIC
COSN28677192 1549 COSMIC
COSN28682587 1612 COSMIC
COSN29192230 1921 COSMIC
COSN31960323 1931 COSMIC
COSN6003789 2045 COSMIC
COSN27244874 2152 COSMIC
COSN31610721 2332 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs749688510 4 dbSNP
rs1254018393 8 dbSNP
rs770439183 11 dbSNP
rs773833051 15 dbSNP
rs992597895 18 dbSNP
rs759248470 25 dbSNP
rs915844018 37 dbSNP
rs376027081 41 dbSNP
rs760552218 42 dbSNP
rs1459542698 45 dbSNP
rs1324868021 48 dbSNP
rs759892114 49 dbSNP
rs369333151 51 dbSNP
rs370012828 53 dbSNP
rs948607927 58 dbSNP
rs980743881 67 dbSNP
rs1321779858 71 dbSNP
rs909256366 73 dbSNP
rs1186961590 75 dbSNP
rs942011702 80 dbSNP
rs897608457 81 dbSNP
rs540338485 82 dbSNP
rs1432982454 85 dbSNP
rs1260958587 87 dbSNP
rs1223989740 88 dbSNP
rs930394073 92 dbSNP
rs1242122531 99 dbSNP
rs1036470491 100 dbSNP
rs1308959830 101 dbSNP
rs1298167249 118 dbSNP
rs897878666 121 dbSNP
rs2736608 128 dbSNP
rs888621883 131 dbSNP
rs1051898699 138 dbSNP
rs1228697313 148 dbSNP
rs528907387 152 dbSNP
rs1311702274 154 dbSNP
rs372237183 159 dbSNP
rs532768558 171 dbSNP
rs1293061440 174 dbSNP
rs1332378697 177 dbSNP
rs1018973745 178 dbSNP
rs889373077 187 dbSNP
rs1421343872 188 dbSNP
rs771442545 197 dbSNP
rs537552840 198 dbSNP
rs1201532215 215 dbSNP
rs998615780 217 dbSNP
rs1207612819 231 dbSNP
rs1481376492 232 dbSNP
rs75890313 235 dbSNP
rs563217449 243 dbSNP
rs904219157 251 dbSNP
rs1206209001 265 dbSNP
rs1276749976 269 dbSNP
rs1317708073 269 dbSNP
rs956675907 271 dbSNP
rs1225861038 272 dbSNP
rs1346773696 273 dbSNP
rs530414833 274 dbSNP
rs1238863826 275 dbSNP
rs1472898292 278 dbSNP
rs565929411 279 dbSNP
rs1022296496 282 dbSNP
rs1397822419 285 dbSNP
rs969201937 287 dbSNP
rs1480714997 293 dbSNP
rs1412137244 306 dbSNP
rs746118819 309 dbSNP
rs759205710 315 dbSNP
rs1377010175 317 dbSNP
rs1473766804 319 dbSNP
rs1420384116 325 dbSNP
rs73006789 330 dbSNP
rs960030095 340 dbSNP
rs1455727220 342 dbSNP
rs1256557648 345 dbSNP
rs992630523 353 dbSNP
rs1336198441 357 dbSNP
rs1206037258 360 dbSNP
rs1324830123 373 dbSNP
rs1360002235 402 dbSNP
rs1255929538 406 dbSNP
rs1022716146 408 dbSNP
rs1231112304 409 dbSNP
rs969864546 410 dbSNP
rs1337635660 413 dbSNP
rs1307857647 416 dbSNP
rs562961630 422 dbSNP
rs1282622544 437 dbSNP
rs1353394706 438 dbSNP
rs1229999090 441 dbSNP
rs566883558 459 dbSNP
rs1470127335 460 dbSNP
rs972364274 461 dbSNP
rs866401730 462 dbSNP
rs1170764191 470 dbSNP
rs1328327203 479 dbSNP
rs751886447 479 dbSNP
rs1221607868 480 dbSNP
rs1455323224 485 dbSNP
rs141836547 501 dbSNP
rs963427997 505 dbSNP
rs930258255 506 dbSNP
rs552662942 507 dbSNP
rs1254950569 512 dbSNP
rs919354780 514 dbSNP
rs1443386566 519 dbSNP
rs942899303 524 dbSNP
rs570837596 535 dbSNP
rs901448853 541 dbSNP
rs1183270073 545 dbSNP
rs1351694790 545 dbSNP
rs998459452 550 dbSNP
rs1051846274 558 dbSNP
rs1052612039 570 dbSNP
rs910757089 571 dbSNP
rs189986996 573 dbSNP
rs943506001 574 dbSNP
rs1413964134 576 dbSNP
rs1332520816 584 dbSNP
rs1385657617 586 dbSNP
rs892468942 590 dbSNP
rs1010827941 595 dbSNP
rs1043338686 599 dbSNP
rs1022369985 600 dbSNP
rs1472289689 600 dbSNP
rs904750133 606 dbSNP
rs200463228 613 dbSNP
rs1411446936 618 dbSNP
rs1368226631 623 dbSNP
rs1491421415 623 dbSNP
rs969480660 623 dbSNP
rs1002475916 624 dbSNP
rs1034874267 624 dbSNP
rs1491218095 624 dbSNP
rs777870872 624 dbSNP
rs1308364968 625 dbSNP
rs998545979 625 dbSNP
rs1053168033 626 dbSNP
rs1197296632 626 dbSNP
rs1216689751 626 dbSNP
rs1274914145 626 dbSNP
rs1277383511 626 dbSNP
rs1288000768 626 dbSNP
rs1318365571 626 dbSNP
rs1330501380 626 dbSNP
rs1347393113 626 dbSNP
rs1347712070 626 dbSNP
rs1370254746 626 dbSNP
rs1460841276 626 dbSNP
rs58631766 626 dbSNP
rs759252806 626 dbSNP
rs763662858 626 dbSNP
rs879145180 626 dbSNP
rs1349616043 627 dbSNP
rs775113425 628 dbSNP
rs895574535 628 dbSNP
rs111363590 629 dbSNP
rs1170492199 630 dbSNP
rs1464506205 632 dbSNP
rs1014000837 633 dbSNP
rs1432103722 637 dbSNP
rs1191777742 639 dbSNP
rs1477760195 644 dbSNP
rs1245157277 645 dbSNP
rs1184225437 646 dbSNP
rs1345190306 647 dbSNP
rs1458415449 647 dbSNP
rs1196589292 652 dbSNP
rs1325513114 652 dbSNP
rs1279280566 654 dbSNP
rs1218056338 656 dbSNP
rs972010561 660 dbSNP
rs1343798409 662 dbSNP
rs1206357702 664 dbSNP
rs1447051963 666 dbSNP
rs919143059 666 dbSNP
rs1375764222 667 dbSNP
rs1177458241 670 dbSNP
rs1464399840 670 dbSNP
rs1491304484 670 dbSNP
rs56120841 670 dbSNP
rs1436414611 672 dbSNP
rs865955308 672 dbSNP
rs1423114518 674 dbSNP
rs1201721275 677 dbSNP
rs969887357 691 dbSNP
rs1477743583 700 dbSNP
rs528247375 710 dbSNP
rs1016862919 711 dbSNP
rs1237891082 725 dbSNP
rs961553538 734 dbSNP
rs972092603 737 dbSNP
rs1357321344 738 dbSNP
rs1285726650 739 dbSNP
rs1240254664 742 dbSNP
rs1040496977 745 dbSNP
rs143838040 759 dbSNP
rs922811757 763 dbSNP
rs954684985 765 dbSNP
rs1015952449 779 dbSNP
rs780571254 784 dbSNP
rs2241108 786 dbSNP
rs910622939 801 dbSNP
rs892711682 808 dbSNP
rs1300055291 828 dbSNP
rs1010885340 830 dbSNP
rs1379864172 832 dbSNP
rs1043695926 841 dbSNP
rs1414243530 846 dbSNP
rs1181121244 847 dbSNP
rs905164461 849 dbSNP
rs1435155558 853 dbSNP
rs762375662 856 dbSNP
rs536148236 858 dbSNP
rs1002312869 859 dbSNP
rs1283325924 864 dbSNP
rs1247683293 865 dbSNP
rs763965134 869 dbSNP
rs1313867160 878 dbSNP
rs896330298 884 dbSNP
rs1043590061 886 dbSNP
rs993324524 892 dbSNP
rs1401195691 896 dbSNP
rs1026276845 897 dbSNP
rs1296496852 901 dbSNP
rs1459624338 903 dbSNP
rs951922131 914 dbSNP
rs1163724545 920 dbSNP
rs1228754413 922 dbSNP
rs1421871675 926 dbSNP
rs926234168 933 dbSNP
rs1194274854 937 dbSNP
rs751524679 943 dbSNP
rs150929217 950 dbSNP
rs1224148677 951 dbSNP
rs975858862 961 dbSNP
rs1264499205 962 dbSNP
rs1221231442 970 dbSNP
rs1320267329 982 dbSNP
rs895522122 986 dbSNP
rs1451492191 1001 dbSNP
rs572818510 1005 dbSNP
rs1219778883 1011 dbSNP
rs1340506319 1018 dbSNP
rs1192271141 1021 dbSNP
rs539823932 1022 dbSNP
rs1388593936 1037 dbSNP
rs1368521915 1043 dbSNP
rs922978666 1048 dbSNP
rs769194439 1050 dbSNP
rs1450151468 1058 dbSNP
rs1402164772 1069 dbSNP
rs1171213157 1070 dbSNP
rs1013864011 1071 dbSNP
rs1421407205 1073 dbSNP
rs368432588 1082 dbSNP
rs1188241680 1088 dbSNP
rs1266112860 1090 dbSNP
rs988265269 1091 dbSNP
rs1481449212 1100 dbSNP
rs140748919 1110 dbSNP
rs774771164 1112 dbSNP
rs1460286584 1120 dbSNP
rs1199673428 1121 dbSNP
rs946984220 1124 dbSNP
rs372127688 1144 dbSNP
rs1294913743 1145 dbSNP
rs1312827045 1157 dbSNP
rs1043934743 1161 dbSNP
rs150088840 1163 dbSNP
rs937977658 1171 dbSNP
rs1056589618 1174 dbSNP
rs1391405609 1178 dbSNP
rs1397978116 1185 dbSNP
rs1005389926 1186 dbSNP
rs1017137831 1192 dbSNP
rs1466523599 1199 dbSNP
rs2540180 1208 dbSNP
rs1173415089 1211 dbSNP
rs1323787995 1211 dbSNP
rs896563123 1213 dbSNP
rs1238408904 1216 dbSNP
rs878913379 1222 dbSNP
rs993357089 1223 dbSNP
rs961233726 1234 dbSNP
rs544867209 1242 dbSNP
rs563077138 1243 dbSNP
rs2540179 1255 dbSNP
rs994525947 1259 dbSNP
rs1202672651 1260 dbSNP
rs2540178 1263 dbSNP
rs1435181995 1269 dbSNP
rs1346417518 1270 dbSNP
rs1006158967 1271 dbSNP
rs1324262843 1278 dbSNP
rs375489511 1281 dbSNP
rs1285196700 1283 dbSNP
rs138561017 1290 dbSNP
rs1239102872 1296 dbSNP
rs560741586 1297 dbSNP
rs367552853 1300 dbSNP
rs2495270 1309 dbSNP
rs1300495349 1311 dbSNP
rs570970763 1312 dbSNP
rs1208117579 1316 dbSNP
rs1259938809 1317 dbSNP
rs964757041 1327 dbSNP
rs746842239 1332 dbSNP
rs140300707 1333 dbSNP
rs557353943 1339 dbSNP
rs1157651556 1340 dbSNP
rs988491742 1341 dbSNP
rs978957599 1360 dbSNP
rs926156794 1361 dbSNP
rs1362421885 1365 dbSNP
rs1190127220 1367 dbSNP
rs116833807 1368 dbSNP
rs946848422 1370 dbSNP
rs1368888694 1375 dbSNP
rs567306277 1376 dbSNP
rs536010893 1383 dbSNP
rs949733185 1386 dbSNP
rs1286877501 1387 dbSNP
rs554470189 1391 dbSNP
rs36005572 1394 dbSNP
rs767086888 1394 dbSNP
rs548588136 1396 dbSNP
rs1351850446 1397 dbSNP
rs2540177 1403 dbSNP
rs1285675336 1405 dbSNP
rs1044003011 1408 dbSNP
rs553049769 1409 dbSNP
rs1457323830 1411 dbSNP
rs1339763711 1421 dbSNP
rs1310512286 1424 dbSNP
rs1401819800 1425 dbSNP
rs1287733233 1428 dbSNP
rs905621200 1429 dbSNP
rs1297117989 1431 dbSNP
rs896595216 1434 dbSNP
rs1392446065 1436 dbSNP
rs941146674 1437 dbSNP
rs929387732 1438 dbSNP
rs1368354327 1445 dbSNP
rs1186401895 1446 dbSNP
rs1047817321 1450 dbSNP
rs1038114913 1452 dbSNP
rs1479125560 1453 dbSNP
rs1263978652 1455 dbSNP
rs887610792 1459 dbSNP
rs1445423211 1464 dbSNP
rs1006023241 1466 dbSNP
rs1382366728 1472 dbSNP
rs897008442 1490 dbSNP
rs1038983352 1497 dbSNP
rs756395151 1497 dbSNP
rs1397466001 1501 dbSNP
rs997215986 1504 dbSNP
rs1341121532 1508 dbSNP
rs1397599146 1513 dbSNP
rs748188454 1513 dbSNP
rs1332427925 1516 dbSNP
rs76810986 1528 dbSNP
rs1404451881 1545 dbSNP
rs2853641 1549 dbSNP
rs1163292985 1551 dbSNP
rs1009942655 1553 dbSNP
rs1424971255 1554 dbSNP
rs1192990392 1557 dbSNP
rs1275103468 1564 dbSNP
rs1290765104 1566 dbSNP
rs1008910576 1571 dbSNP
rs1330363604 1574 dbSNP
rs558265556 1575 dbSNP
rs1259084222 1591 dbSNP
rs1199811909 1592 dbSNP
rs1017578538 1596 dbSNP
rs1250895411 1602 dbSNP
rs2075163 1612 dbSNP
rs979291012 1614 dbSNP
rs1257383837 1632 dbSNP
rs1212250623 1641 dbSNP
rs1346482465 1642 dbSNP
rs1485227149 1649 dbSNP
rs1435289297 1650 dbSNP
rs1185464234 1658 dbSNP
rs1324221999 1659 dbSNP
rs1449501662 1670 dbSNP
rs968220643 1672 dbSNP
rs1472856084 1678 dbSNP
rs1158257308 1679 dbSNP
rs1170564775 1683 dbSNP
rs544335311 1699 dbSNP
rs1033085836 1704 dbSNP
rs747548076 1705 dbSNP
rs1173294277 1706 dbSNP
rs192987568 1707 dbSNP
rs1251379636 1720 dbSNP
rs377240566 1722 dbSNP
rs547670728 1722 dbSNP
rs917505681 1726 dbSNP
rs1237396783 1729 dbSNP
rs1202321642 1739 dbSNP
rs745627016 1746 dbSNP
rs992396471 1747 dbSNP
rs575110562 1752 dbSNP
rs917944744 1754 dbSNP
rs1240484211 1761 dbSNP
rs776470578 1771 dbSNP
rs1047852524 1775 dbSNP
rs1440633966 1776 dbSNP
rs1361420510 1777 dbSNP
rs1374409942 1778 dbSNP
rs909289536 1782 dbSNP
rs980317523 1785 dbSNP
rs542421936 1795 dbSNP
rs941024193 1796 dbSNP
rs1351452034 1798 dbSNP
rs560877626 1809 dbSNP
rs941882944 1816 dbSNP
rs1379451753 1822 dbSNP
rs1175277804 1832 dbSNP
rs1038550763 1836 dbSNP
rs1238011101 1837 dbSNP
rs1208753498 1838 dbSNP
rs896878569 1839 dbSNP
rs1039261695 1846 dbSNP
rs184015496 1854 dbSNP
rs929812548 1857 dbSNP
rs113886250 1858 dbSNP
rs1222429457 1859 dbSNP
rs900305083 1862 dbSNP
rs1285326156 1864 dbSNP
rs997860027 1865 dbSNP
rs1373679336 1872 dbSNP
rs1051647824 1881 dbSNP
rs1420474281 1886 dbSNP
rs891469759 1898 dbSNP
rs777041205 1899 dbSNP
rs891051770 1905 dbSNP
rs1414320210 1908 dbSNP
rs1006853011 1909 dbSNP
rs1018199416 1910 dbSNP
rs900531736 1920 dbSNP
rs759295968 1923 dbSNP
rs1193771903 1924 dbSNP
rs1487721068 1925 dbSNP
rs1001067983 1926 dbSNP
rs1253761428 1931 dbSNP
rs1000184287 1934 dbSNP
rs546428604 1941 dbSNP
rs1176613027 1954 dbSNP
rs564330744 1957 dbSNP
rs531695213 1960 dbSNP
rs1033522211 1962 dbSNP
rs1280098238 1966 dbSNP
rs918141513 1967 dbSNP
rs1434406681 1968 dbSNP
rs1361467139 1975 dbSNP
rs868011006 1976 dbSNP
rs1010360278 1984 dbSNP
rs549884422 1989 dbSNP
rs983449508 2001 dbSNP
rs188354213 2010 dbSNP
rs971529374 2015 dbSNP
rs1483318490 2016 dbSNP
rs1170728905 2017 dbSNP
rs980349795 2025 dbSNP
rs1259117690 2026 dbSNP
rs1039094300 2034 dbSNP
rs921764047 2037 dbSNP
rs1247645884 2040 dbSNP
rs1213462291 2044 dbSNP
rs1333277319 2047 dbSNP
rs375267605 2054 dbSNP
rs796951171 2054 dbSNP
rs927548939 2055 dbSNP
rs1219831757 2061 dbSNP
rs1306960631 2075 dbSNP
rs1051665070 2080 dbSNP
rs1368589751 2081 dbSNP
rs746286566 2082 dbSNP
rs962710338 2083 dbSNP
rs373906181 2085 dbSNP
rs1296962769 2101 dbSNP
rs1324897609 2104 dbSNP
rs1438483290 2106 dbSNP
rs180920264 2110 dbSNP
rs1331931359 2115 dbSNP
rs1461460561 2130 dbSNP
rs1370843326 2136 dbSNP
rs1185557013 2141 dbSNP
rs1177683723 2150 dbSNP
rs1370292311 2155 dbSNP
rs1433355381 2161 dbSNP
rs1394130861 2169 dbSNP
rs1387451858 2175 dbSNP
rs1302717279 2177 dbSNP
rs891710352 2178 dbSNP
rs1199816827 2184 dbSNP
rs759263966 2188 dbSNP
rs1249629799 2189 dbSNP
rs1042689735 2197 dbSNP
rs1230959729 2210 dbSNP
rs918341463 2218 dbSNP
rs1342609155 2220 dbSNP
rs1302981620 2221 dbSNP
rs1203479145 2223 dbSNP
rs929702851 2225 dbSNP
rs183504198 2230 dbSNP
rs904166410 2234 dbSNP
rs1331870448 2245 dbSNP
rs1001711855 2253 dbSNP
rs1394268384 2254 dbSNP
rs1034065976 2255 dbSNP
rs895313459 2257 dbSNP
rs769421518 2260 dbSNP
rs1013747170 2262 dbSNP
rs1050830091 2266 dbSNP
rs768478438 2270 dbSNP
rs565300609 2275 dbSNP
rs533850119 2297 dbSNP
rs1039668079 2302 dbSNP
rs903747641 2319 dbSNP
rs1801776 2324 dbSNP
rs1418936135 2331 dbSNP
rs950927147 2332 dbSNP
rs1202200931 2335 dbSNP
rs1352155446 2340 dbSNP
rs1486027597 2354 dbSNP
rs1279757505 2356 dbSNP
rs1000611464 2358 dbSNP
rs12025011 2359 dbSNP
rs983480566 2363 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 9673.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cggacaggGAUUUAGGAAGGAc 5'
                  :| |  ||||||| 
Target 5' --------UUUAUCCCUUCCUg 3'
 		1 - 14
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_014655 | 3UTR | AUCCCUUCCUGCACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_014655 | 3UTR | CCCCUUCCUAAGACAGGUAGAAAAAUGUAAUGUAGCUUUUUCCACAAGCCACUUCCCUGUCCCUUCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_014655 | 3UTR | CCCCCUUCCUAAGACAGGUAGAAAAAUGUAAUGUAGCUUUUUCCACAAGCCACUUCCCUGUCCCUUCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_014655 | 3UTR | GCCAAGAUUAUCUGAUGCUCUCCUCAGGAGCUAGGAGAGGAGUGCUCCUUCCUCCCUACCGCUACUCUCCCCAAGCCUGUGUUGCAGGUAGAGAGGUGCAGCAAAUAGAGAAGGCAUGUCAAACCCUGCAUUUCUACCUGAGACGUGUGACCUGGAUGAUCCUCCAAACCCUAUUGGUCCCACCCCCUGGGAAAGGCCAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_014655 | 3UTR | UGCAUUUACCAGCCUGAUACUGCCAAGAUUAUCUGAUGCUCUCCUCAGGAGCUAGGAGAGGAGUGCUCCUUCCUCCCUACCGCUACUCUCCCCAAGCCUGUGUUGCAGGUAGAGAGGUGCAGCAAAUAGAGAAGGCAUGUCAAACCCUGCAUUUCUACCUGAGACGUGUGACCUGGAUGAUCCUCCAAACCCUAUUGGUCCCACCCCCUGGGAAAGGCCAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000359511.4 | 3UTR | UUUAUCCCUUCCUGCACUUUGUCAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000359511.4 | 3UTR | UUUAUCCCUUCCUGCACUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
152 hsa-miR-4476 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT065631 CLIC4 chloride intracellular channel 4 2 2
MIRT076187 GID4 GID complex subunit 4 homolog 2 4
MIRT086304 HOXD8 homeobox D8 2 6
MIRT110644 ARID5B AT-rich interaction domain 5B 2 2
MIRT144337 NFAT5 nuclear factor of activated T-cells 5 2 2
MIRT196634 TAOK1 TAO kinase 1 2 6
MIRT227655 SET SET nuclear proto-oncogene 2 2
MIRT263546 PPIF peptidylprolyl isomerase F 2 4
MIRT266189 TXNIP thioredoxin interacting protein 2 4
MIRT266815 SLC25A44 solute carrier family 25 member 44 2 2
MIRT285538 CDT1 chromatin licensing and DNA replication factor 1 2 2
MIRT295094 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT300906 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT304110 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 6
MIRT314891 RGMB repulsive guidance molecule family member b 2 2
MIRT364225 ANP32B acidic nuclear phosphoprotein 32 family member B 2 2
MIRT366237 VMA21 VMA21, vacuolar ATPase assembly factor 2 2
MIRT405440 RAB5B RAB5B, member RAS oncogene family 2 2
MIRT443613 OR2D2 olfactory receptor family 2 subfamily D member 2 2 2
MIRT445947 SCML4 Scm polycomb group protein like 4 2 2
MIRT445957 MLLT11 MLLT11, transcription factor 7 cofactor 2 2
MIRT445970 IKZF5 IKAROS family zinc finger 5 2 2
MIRT448066 MMP15 matrix metallopeptidase 15 2 2
MIRT449498 ZBTB4 zinc finger and BTB domain containing 4 2 2
MIRT450831 IFFO1 intermediate filament family orphan 1 2 2
MIRT451270 NDUFA11 NADH:ubiquinone oxidoreductase subunit A11 2 2
MIRT451318 LGALS3BP galectin 3 binding protein 2 2
MIRT451403 FARSA phenylalanyl-tRNA synthetase alpha subunit 2 2
MIRT451941 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452028 NLRP6 NLR family pyrin domain containing 6 2 2
MIRT452503 HMGXB3 HMG-box containing 3 2 2
MIRT453852 SDK1 sidekick cell adhesion molecule 1 2 2
MIRT454523 ZFYVE27 zinc finger FYVE-type containing 27 2 2
MIRT455402 PLA2G2F phospholipase A2 group IIF 2 2
MIRT455442 ID3 inhibitor of DNA binding 3, HLH protein 2 2
MIRT456983 MANEA mannosidase endo-alpha 2 2
MIRT457610 IDS iduronate 2-sulfatase 2 2
MIRT458319 TNFAIP8L3 TNF alpha induced protein 8 like 3 2 2
MIRT458756 CES2 carboxylesterase 2 2 2
MIRT458960 SAMD4B sterile alpha motif domain containing 4B 2 2
MIRT460403 GPHA2 glycoprotein hormone alpha 2 2 2
MIRT460632 IGFBP4 insulin like growth factor binding protein 4 2 2
MIRT461760 DDX11 DEAD/H-box helicase 11 2 2
MIRT461924 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT461977 PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2 2
MIRT462271 TPI1 triosephosphate isomerase 1 2 2
MIRT462304 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT462725 SEMA4G semaphorin 4G 2 2
MIRT463414 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463525 ZBTB7B zinc finger and BTB domain containing 7B 2 2
MIRT464089 VPS4A vacuolar protein sorting 4 homolog A 2 2
MIRT464623 UBE4B ubiquitination factor E4B 2 2
MIRT465030 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT465562 TOB2 transducer of ERBB2, 2 2 2
MIRT465890 TMEM43 transmembrane protein 43 2 2
MIRT466428 TFAP2A transcription factor AP-2 alpha 2 8
MIRT466593 TBC1D2B TBC1 domain family member 2B 2 2
MIRT467623 SLC7A5 solute carrier family 7 member 5 2 2
MIRT468511 SESN2 sestrin 2 2 2
MIRT468649 SEH1L SEH1 like nucleoporin 2 2
MIRT468737 SDC4 syndecan 4 2 2
MIRT468752 SDC2 syndecan 2 2 2
MIRT469182 RNF111 ring finger protein 111 2 2
MIRT469476 REEP5 receptor accessory protein 5 2 2
MIRT472078 NOVA2 NOVA alternative splicing regulator 2 2 2
MIRT472093 NOLC1 nucleolar and coiled-body phosphoprotein 1 2 2
MIRT472194 NHP2L1 small nuclear ribonucleoprotein 13 2 2
MIRT472453 NAV2 neuron navigator 2 2 6
MIRT474493 KLHDC8B kelch domain containing 8B 2 2
MIRT475174 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT475350 IFNLR1 interferon lambda receptor 1 2 2
MIRT476474 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT477094 FAM168A family with sequence similarity 168 member A 2 2
MIRT477179 F3 coagulation factor III, tissue factor 2 6
MIRT478026 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT479587 CDC42SE1 CDC42 small effector 1 2 2
MIRT480117 CALR calreticulin 2 2
MIRT480465 C11orf84 chromosome 11 open reading frame 84 2 2
MIRT480803 BLOC1S2 biogenesis of lysosomal organelles complex 1 subunit 2 2 6
MIRT481076 B4GALT1 beta-1,4-galactosyltransferase 1 2 2
MIRT482576 ABHD2 abhydrolase domain containing 2 2 2
MIRT482690 NXN nucleoredoxin 2 4
MIRT483599 SLC26A9 solute carrier family 26 member 9 2 2
MIRT485011 TNRC6B trinucleotide repeat containing 6B 2 4
MIRT488051 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 2
MIRT488067 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 2
MIRT488176 PRRC2B proline rich coiled-coil 2B 2 4
MIRT488859 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT489074 STARD3 StAR related lipid transfer domain containing 3 2 2
MIRT489181 ANKRD45 ankyrin repeat domain 45 2 2
MIRT489981 DDB1 damage specific DNA binding protein 1 2 2
MIRT490225 WRN Werner syndrome RecQ like helicase 2 2
MIRT491084 HILPDA hypoxia inducible lipid droplet associated 2 2
MIRT491540 HDAC5 histone deacetylase 5 2 2
MIRT492540 PSMD11 proteasome 26S subunit, non-ATPase 11 2 2
MIRT499034 MAG myelin associated glycoprotein 2 2
MIRT499420 PLCG2 phospholipase C gamma 2 2 4
MIRT499820 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT500046 SDE2 SDE2 telomere maintenance homolog 2 6
MIRT500844 SYPL1 synaptophysin like 1 2 4
MIRT504518 PPP1R9B protein phosphatase 1 regulatory subunit 9B 2 2
MIRT505622 SLC25A37 solute carrier family 25 member 37 2 2
MIRT509134 STK4 serine/threonine kinase 4 2 2
MIRT509219 BUB3 BUB3, mitotic checkpoint protein 2 4
MIRT510752 SLC7A1 solute carrier family 7 member 1 2 2
MIRT512115 CREBZF CREB/ATF bZIP transcription factor 2 2
MIRT512317 ACTR2 ARP2 actin related protein 2 homolog 2 6
MIRT517395 BGN biglycan 2 4
MIRT518412 SSU72 SSU72 homolog, RNA polymerase II CTD phosphatase 2 4
MIRT521362 RPL35A ribosomal protein L35a 2 2
MIRT525072 FRK fyn related Src family tyrosine kinase 2 2
MIRT525800 SOD2 superoxide dismutase 2 2 2
MIRT530430 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT541467 AURKA aurora kinase A 2 2
MIRT544303 TSPYL1 TSPY like 1 2 2
MIRT546415 SPRED3 sprouty related EVH1 domain containing 3 2 2
MIRT546582 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT548764 CNN3 calponin 3 2 2
MIRT549809 KIAA0391 KIAA0391 2 2
MIRT550611 MTHFR methylenetetrahydrofolate reductase 2 2
MIRT552227 FIG4 FIG4 phosphoinositide 5-phosphatase 2 4
MIRT554008 SPTLC1 serine palmitoyltransferase long chain base subunit 1 2 2
MIRT554116 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT555100 PURB purine rich element binding protein B 2 2
MIRT560290 HRH2 histamine receptor H2 2 2
MIRT560381 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT560800 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT560978 IWS1 IWS1, SUPT6H interacting protein 2 2
MIRT561161 BCL2L12 BCL2 like 12 2 2
MIRT562389 EN2 engrailed homeobox 2 2 2
MIRT562482 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT567784 DGAT2 diacylglycerol O-acyltransferase 2 2 2
MIRT568831 TRIM67 tripartite motif containing 67 2 2
MIRT569555 UNC119B unc-119 lipid binding chaperone B 2 2
MIRT572382 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT575792 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b 2 2
MIRT610505 CTBS chitobiase 2 4
MIRT616605 PAPD5 poly(A) RNA polymerase D5, non-canonical 2 2
MIRT621780 TMEM87B transmembrane protein 87B 2 2
MIRT634217 TMEM192 transmembrane protein 192 2 2
MIRT639651 WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules 2 2
MIRT642500 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT643217 TYW3 tRNA-yW synthesizing protein 3 homolog 2 4
MIRT674822 KCNJ10 potassium voltage-gated channel subfamily J member 10 2 2
MIRT697356 ZNF426 zinc finger protein 426 2 2
MIRT704675 CHTOP chromatin target of PRMT1 2 2
MIRT708704 TFDP2 transcription factor Dp-2 2 2
MIRT709660 DFFB DNA fragmentation factor subunit beta 2 2
MIRT711280 SDR9C7 short chain dehydrogenase/reductase family 9C member 7 2 2
MIRT713733 SUCO SUN domain containing ossification factor 2 2
MIRT715006 TSPAN11 tetraspanin 11 2 2
MIRT718400 ALDH1A3 aldehyde dehydrogenase 1 family member A3 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miR-4476 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4476 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4476 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4476 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4476 Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-mir-4476 Androstenedione 6128 NSC9563 resistant cell line (MCF-7)
hsa-mir-4476 Androstenedione+Anastrozole resistant cell line (MCF-7)
hsa-mir-4476 Androstenedione+Letrozole resistant cell line (MCF-7)
hsa-miR-4476 Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-4476 Paclitaxel 36314 NSC125973 approved sensitive cell line (HS578T)
hsa-miR-4476 Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4476 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4476 Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-4476 Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-4476 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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