miRTarBase - #MIRT267302


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pre-miRNA Information
pre-miRNA hsa-mir-3175   
Genomic Coordinates chr15: 92904399 - 92904475
Description Homo sapiens miR-3175 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3175
Sequence 10| CGGGGAGAGAACGCAGUGACGU |31
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1449291045 4 dbSNP
rs372141302 4 dbSNP
rs72647784 4 dbSNP
rs1209664292 5 dbSNP
rs563454166 6 dbSNP
rs915251599 19 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TMEM109   
Synonyms -
Description transmembrane protein 109
Transcript NM_024092   
Expression
Putative miRNA Targets on TMEM109
3'UTR of TMEM109
(miRNA target sites are highlighted)		 
>TMEM109|NM_024092|3'UTR
   1 GCCGGATGCCCCACACACCGCCAGTGTCATACCAAAGAGCTGAGCTGCTTCGGGGCCATGCAGCCCTCCTGCCAGCCCCC
  81 TGCCCTTTTCTTGCCCTGTCTCTGAACCTTCAGAACATTGATCCTTGCCGCAGCCCCACTAGCCAAGAGAAACAGAGAAA
 161 GACCATTCCCCCTGCCTGTCCTTGCGGCCCTGTCTTCTGAGGTTCTCTGTCTGGGGTTGGCTCTCTTAACCCTTTCTCTG
 241 CTCCCAGCCTGCCTCACCAGGGAAGGTTGGAGGGGCCTCCCTCTGGCTTCTGCATCTGCGCCAGCAAACATCACTGCCGT
 321 TGGTCTCTCATGACTTAACTGGCTTCCCTCTGCTGCTGCCTTGGCTTCCTCCTAATGCTCGTGCTCTCCTGTCCTTCTGA
 401 AGTTGCTCCTTGGCCAAATCTCCAGCTCCCTTCTTGTTTTCCTCATCCTCCTACCCTGTACTCCCACCAAACCATGGTCC
 481 TTTAAGGCACGCTCCTGTCCTCCTCATTGCCCAGCAGTAGGGAGGGGCAGGGGTAAGGGGACCTGAGGATAAAGGGTGGG
 561 GAAACAGGGTCCCCTGAGGCCTGTGGGGGCTGCAGGGGAGGAGGATGTACCTTGTGTCTCTTTCAAGTGCCTTAATCCGA
 641 GCCAGCAGGGCCTTCTGCTTGCCTGCTGCCATACTGTATGTAGGAAAGTGTTCTGTGGCTGCTTTGTGTCAAGAAAAGAG
 721 CAGTCACTCTCAGAATCTTGATTCCCCATCAGCCAAAGCAAAAGATGGCTGCTGCTTTGTAGGCATGTGCCTGCAAGTGG
 801 GACCTTGCTGGGCATTATATGCCCTGTGGGGGTTTCAGAGACCCTGAAAGAGGAGGGAGGACCCGCCTCCTTGTCTGCAC
 881 AACTGCATGCACTTCTCTCCCCATCGCTCCACAACCTGAAACCGAGAAGGAGTTGCTGACCAGTGCCCACCCCGGCAGCC
 961 CGGGAGGAACACAGGCAGCTCCTTTCCCTTCACGTGGTCTGCAGAGAGCAGGGTGAGCTGCCAGCTGCCCCTCTCCACCA
1041 GGGTACCCTGTCTTGGTGGTTAGGGGCCACTTTTCCTTTGAGGCTCTAGTGGAGGTGGATGTCCTTCTCTGCCAGGCTTG
1121 GCACATGATGTGAAGAATAAATGCCCAATTCTTACTGTTCAGGTTTGATGTGGAATCACAGCTGCAGTGATATATATTTT
1201 TTATCAGTGCTTGGTTGGTTTTAAATAAAGTGCACGCTATTTTATTATCTTGTTCTGAATAAAATGTATTTACTCCAAAA
1281 AAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugcagUGACG--C---AAGAGAGGGGc 5'
               |||||  |   |||||||||| 
Target 5' gcacaACTGCATGCACTTCTCTCCCCa 3'
 877 - 903 163.00 -20.80
2 
miRNA  3' ugcAGUGAC-GCAA-GAGAGGGgc 5'
             |||||| ||||  ||||:|  
Target 5' acaTCACTGCCGTTGGTCTCTCat 3'
 308 - 331 135.00 -18.90
3 
miRNA  3' ugcAGUGACGCAAGAGAGGGGc 5'
             || || | | :|:|||:| 
Target 5' agcTCCCTTCTTGTTTTCCTCa 3'
 424 - 445 127.00 -9.25
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31544507 3 COSMIC
COSN30608567 5 COSMIC
COSN28777778 20 COSMIC
COSN31490676 43 COSMIC
COSN18714083 46 COSMIC
COSN30715339 145 COSMIC
COSN31593726 154 COSMIC
COSN31536339 160 COSMIC
COSN20108314 217 COSMIC
COSN20077216 253 COSMIC
COSN6533371 300 COSMIC
COSN20215147 397 COSMIC
COSN31533944 547 COSMIC
COSN31513375 604 COSMIC
COSN26537892 612 COSMIC
COSN30539665 626 COSMIC
COSN5915839 648 COSMIC
COSN8686668 924 COSMIC
COSN1539888 949 COSMIC
COSN32132755 994 COSMIC
COSN16132025 1005 COSMIC
COSN30168273 1005 COSMIC
COSN16131994 1044 COSMIC
COSN31578952 1077 COSMIC
COSN31607285 1152 COSMIC
COSN30168264 1174 COSMIC
COSN31513308 1236 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1410206782 2 dbSNP
rs755261364 4 dbSNP
rs781503937 5 dbSNP
rs1362287186 7 dbSNP
rs891814742 10 dbSNP
rs1337211570 11 dbSNP
rs1405231570 12 dbSNP
rs752914482 16 dbSNP
rs887919995 17 dbSNP
rs1218406571 19 dbSNP
rs1373362366 20 dbSNP
rs766172529 21 dbSNP
rs1297202209 26 dbSNP
rs1304327558 27 dbSNP
rs1325319302 29 dbSNP
rs1225712821 31 dbSNP
rs777885347 34 dbSNP
rs1323315166 35 dbSNP
rs372992625 38 dbSNP
rs1235120380 40 dbSNP
rs1480964412 49 dbSNP
rs1176759398 51 dbSNP
rs1249871367 52 dbSNP
rs757187457 53 dbSNP
rs1176844520 55 dbSNP
rs1428286740 57 dbSNP
rs1468058564 59 dbSNP
rs1172373501 72 dbSNP
rs1355041062 76 dbSNP
rs1440821113 78 dbSNP
rs778779220 79 dbSNP
rs575153581 81 dbSNP
rs1405135828 90 dbSNP
rs1282271088 95 dbSNP
rs1345213193 97 dbSNP
rs547079216 98 dbSNP
rs1275718792 101 dbSNP
rs1308657781 103 dbSNP
rs1203879030 107 dbSNP
rs1330501162 108 dbSNP
rs992403212 110 dbSNP
rs1490868945 112 dbSNP
rs1007174957 113 dbSNP
rs775183914 115 dbSNP
rs1019427989 118 dbSNP
rs1268463327 119 dbSNP
rs1476879380 120 dbSNP
rs560676157 124 dbSNP
rs529459273 130 dbSNP
rs1409346684 131 dbSNP
rs1168276749 134 dbSNP
rs1456681159 136 dbSNP
rs1366841065 140 dbSNP
rs1424765135 146 dbSNP
rs952363967 147 dbSNP
rs1271605130 153 dbSNP
rs765022125 154 dbSNP
rs775322843 161 dbSNP
rs1235842359 165 dbSNP
rs746705399 167 dbSNP
rs1272336926 171 dbSNP
rs1363232301 173 dbSNP
rs1214450908 175 dbSNP
rs768411305 176 dbSNP
rs1361607436 180 dbSNP
rs1308384453 186 dbSNP
rs1223326576 187 dbSNP
rs1298513155 191 dbSNP
rs1016563641 197 dbSNP
rs1291310375 206 dbSNP
rs1450145239 210 dbSNP
rs138560883 213 dbSNP
rs1455598201 214 dbSNP
rs978178097 215 dbSNP
rs1474973841 218 dbSNP
rs1178524331 221 dbSNP
rs1417820397 223 dbSNP
rs1332900503 226 dbSNP
rs776297232 227 dbSNP
rs563364012 231 dbSNP
rs776396724 239 dbSNP
rs1196728883 241 dbSNP
rs114542191 245 dbSNP
rs936484614 248 dbSNP
rs985701811 249 dbSNP
rs1212433466 252 dbSNP
rs988915409 258 dbSNP
rs759111204 263 dbSNP
rs1307864449 265 dbSNP
rs537084399 268 dbSNP
rs775421067 272 dbSNP
rs1337450016 276 dbSNP
rs911099179 278 dbSNP
rs943929986 286 dbSNP
rs574933226 290 dbSNP
rs1311239556 293 dbSNP
rs143533895 294 dbSNP
rs1041015357 295 dbSNP
rs746771915 297 dbSNP
rs1043036398 300 dbSNP
rs764616924 301 dbSNP
rs1366052772 306 dbSNP
rs1182988490 310 dbSNP
rs1423553502 312 dbSNP
rs1412583060 319 dbSNP
rs147127792 320 dbSNP
rs1048106761 321 dbSNP
rs764140481 331 dbSNP
rs888194367 331 dbSNP
rs1284765520 338 dbSNP
rs1202854323 345 dbSNP
rs539162919 351 dbSNP
rs1352758148 357 dbSNP
rs1041333194 372 dbSNP
rs1243821112 377 dbSNP
rs552610101 381 dbSNP
rs1055692877 382 dbSNP
rs895345735 394 dbSNP
rs368958227 395 dbSNP
rs1356321296 402 dbSNP
rs1025199138 406 dbSNP
rs1387791270 409 dbSNP
rs758776978 411 dbSNP
rs1457816872 415 dbSNP
rs1416208704 421 dbSNP
rs1005243104 424 dbSNP
rs572705101 429 dbSNP
rs761700111 430 dbSNP
rs535269732 441 dbSNP
rs1190419607 451 dbSNP
rs969430371 454 dbSNP
rs1001810936 460 dbSNP
rs966653811 462 dbSNP
rs1036311713 463 dbSNP
rs1332555075 464 dbSNP
rs1281208789 472 dbSNP
rs960244439 478 dbSNP
rs555677139 479 dbSNP
rs1269763779 485 dbSNP
rs386754110 487 dbSNP
rs77661705 488 dbSNP
rs1044765 489 dbSNP
rs757588431 491 dbSNP
rs985598334 492 dbSNP
rs911048180 493 dbSNP
rs1165750482 495 dbSNP
rs1429486099 498 dbSNP
rs1193032882 501 dbSNP
rs1306991072 503 dbSNP
rs781443289 504 dbSNP
rs1197529301 510 dbSNP
rs777249551 513 dbSNP
rs564336997 516 dbSNP
rs942673606 522 dbSNP
rs965233460 534 dbSNP
rs1040971311 535 dbSNP
rs759954258 539 dbSNP
rs922501322 542 dbSNP
rs750447751 544 dbSNP
rs1457114551 558 dbSNP
rs976635077 569 dbSNP
rs1046910337 573 dbSNP
rs1341720918 589 dbSNP
rs888226475 590 dbSNP
rs918513283 592 dbSNP
rs1371837315 596 dbSNP
rs1005318445 604 dbSNP
rs540865811 608 dbSNP
rs1442136263 613 dbSNP
rs929617720 617 dbSNP
rs1327239256 621 dbSNP
rs1479329937 623 dbSNP
rs1396763420 625 dbSNP
rs1171489502 627 dbSNP
rs1173679055 629 dbSNP
rs1451969173 631 dbSNP
rs1396834760 632 dbSNP
rs376759347 634 dbSNP
rs1438984789 639 dbSNP
rs1044812393 640 dbSNP
rs376261616 649 dbSNP
rs1048531526 650 dbSNP
rs1273911473 653 dbSNP
rs1210290105 656 dbSNP
rs1282524296 663 dbSNP
rs1345768925 663 dbSNP
rs904858950 665 dbSNP
rs1373226310 674 dbSNP
rs1381452968 675 dbSNP
rs1316029916 682 dbSNP
rs1444730676 685 dbSNP
rs1003587556 694 dbSNP
rs1175241004 703 dbSNP
rs1311845978 711 dbSNP
rs141439252 711 dbSNP
rs370715717 711 dbSNP
rs1376801542 713 dbSNP
rs1233944902 722 dbSNP
rs1400115007 723 dbSNP
rs1405616664 743 dbSNP
rs578038931 749 dbSNP
rs1233702088 768 dbSNP
rs1187554747 769 dbSNP
rs937072514 776 dbSNP
rs1055492400 790 dbSNP
rs540732391 798 dbSNP
rs1020399323 799 dbSNP
rs895294910 815 dbSNP
rs1282698489 816 dbSNP
rs968830814 820 dbSNP
rs1232280857 822 dbSNP
rs1013720096 826 dbSNP
rs1351796083 841 dbSNP
rs1293040703 844 dbSNP
rs1412607503 852 dbSNP
rs1356971130 854 dbSNP
rs978835596 857 dbSNP
rs1312964184 862 dbSNP
rs1046598098 866 dbSNP
rs1343391621 885 dbSNP
rs554083577 888 dbSNP
rs1401190758 889 dbSNP
rs999821153 892 dbSNP
rs977153343 893 dbSNP
rs922566917 894 dbSNP
rs1259787430 897 dbSNP
rs929867917 902 dbSNP
rs1204916555 903 dbSNP
rs1032751159 906 dbSNP
rs958095464 907 dbSNP
rs1007369606 910 dbSNP
rs1018391719 911 dbSNP
rs1231772391 914 dbSNP
rs965171599 916 dbSNP
rs1293479511 924 dbSNP
rs976582713 925 dbSNP
rs1359308044 929 dbSNP
rs1290096446 931 dbSNP
rs7116175 944 dbSNP
rs1431461586 948 dbSNP
rs1393631346 951 dbSNP
rs1323646366 953 dbSNP
rs560563333 954 dbSNP
rs939070984 955 dbSNP
rs34697422 962 dbSNP
rs951366177 962 dbSNP
rs140318423 963 dbSNP
rs1417533701 970 dbSNP
rs1364005361 974 dbSNP
rs1056516328 977 dbSNP
rs1450644416 989 dbSNP
rs549294313 994 dbSNP
rs909519293 995 dbSNP
rs937040335 997 dbSNP
rs1055441048 998 dbSNP
rs1203443088 1006 dbSNP
rs1441498307 1010 dbSNP
rs1010460007 1012 dbSNP
rs577436170 1013 dbSNP
rs1438790866 1022 dbSNP
rs949516207 1023 dbSNP
rs546533756 1031 dbSNP
rs1442871964 1036 dbSNP
rs1046547991 1037 dbSNP
rs902716849 1038 dbSNP
rs1259278035 1041 dbSNP
rs1352914770 1041 dbSNP
rs1172640648 1042 dbSNP
rs1430433754 1043 dbSNP
rs935570513 1048 dbSNP
rs1192355951 1049 dbSNP
rs1054068695 1055 dbSNP
rs1455950753 1058 dbSNP
rs1214786563 1062 dbSNP
rs61899181 1067 dbSNP
rs1252936436 1069 dbSNP
rs1467570100 1071 dbSNP
rs1252637765 1082 dbSNP
rs1179966132 1085 dbSNP
rs893778230 1087 dbSNP
rs1277529778 1088 dbSNP
rs73493043 1099 dbSNP
rs867855603 1102 dbSNP
rs1371636578 1104 dbSNP
rs531933456 1105 dbSNP
rs1306032118 1109 dbSNP
rs1418102111 1118 dbSNP
rs1156534569 1122 dbSNP
rs1018329931 1136 dbSNP
rs901253362 1145 dbSNP
rs1374980854 1147 dbSNP
rs1437193187 1149 dbSNP
rs998302943 1149 dbSNP
rs1378649493 1165 dbSNP
rs1392202241 1168 dbSNP
rs1025468238 1171 dbSNP
rs189007301 1179 dbSNP
rs909765629 1180 dbSNP
rs1182500716 1192 dbSNP
rs984421181 1194 dbSNP
rs1212324797 1195 dbSNP
rs1374174274 1205 dbSNP
rs1345648886 1210 dbSNP
rs1390998045 1219 dbSNP
rs772198873 1232 dbSNP
rs773248440 1236 dbSNP
rs142212430 1237 dbSNP
rs980598102 1250 dbSNP
rs746847075 1255 dbSNP
rs958581793 1256 dbSNP
rs770798371 1266 dbSNP
rs776381052 1267 dbSNP
rs1403562787 1269 dbSNP
rs1288756358 1270 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ugcagUGACG--C---AAGAGAGGGGc 5'
               |||||  |   |||||||||| 
Target 5' -cacaACUGCAUGCACUUCUCUCCCCa 3'
 		1 - 26
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545212
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / Control
Location of target site ENST00000227525.3 | 3UTR | CACAACUGCAUGCACUUCUCUCCCCAUCG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
Click to see details
208 hsa-miR-3175 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT118211 KHSRP KH-type splicing regulatory protein 2 2
MIRT131222 ATG2A autophagy related 2A 2 2
MIRT143733 CCL22 C-C motif chemokine ligand 22 2 2
MIRT151435 ZBTB7A zinc finger and BTB domain containing 7A 2 4
MIRT191759 ZNF410 zinc finger protein 410 2 2
MIRT267302 TMEM109 transmembrane protein 109 2 2
MIRT273435 DAZAP2 DAZ associated protein 2 2 4
MIRT286061 HIC1 HIC ZBTB transcriptional repressor 1 2 2
MIRT288597 DCAF7 DDB1 and CUL4 associated factor 7 2 2
MIRT316768 FOXC1 forkhead box C1 2 4
MIRT331065 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 4
MIRT398528 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 2 2
MIRT443842 RGS6 regulator of G protein signaling 6 2 2
MIRT446200 GTPBP4 GTP binding protein 4 2 2
MIRT448039 SFRP1 secreted frizzled related protein 1 2 2
MIRT451946 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT453239 FTSJ3 FtsJ RNA methyltransferase homolog 3 2 2
MIRT453501 ARRB1 arrestin beta 1 2 2
MIRT453541 PRR12 proline rich 12 2 2
MIRT453953 ENTHD1 ENTH domain containing 1 2 2
MIRT454209 HLA-A major histocompatibility complex, class I, A 2 2
MIRT455501 C6orf106 chromosome 6 open reading frame 106 2 2
MIRT455620 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 10
MIRT455631 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 10
MIRT456074 AFF2 AF4/FMR2 family member 2 2 6
MIRT456149 TTF2 transcription termination factor 2 2 2
MIRT456309 ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 2 2
MIRT456444 TMEM81 transmembrane protein 81 2 2
MIRT456685 LDB1 LIM domain binding 1 2 2
MIRT457516 ZMAT5 zinc finger matrin-type 5 2 2
MIRT457599 IDS iduronate 2-sulfatase 2 2
MIRT457949 ABCC5 ATP binding cassette subfamily C member 5 2 6
MIRT458593 KCTD2 potassium channel tetramerization domain containing 2 2 2
MIRT459505 TACR3 tachykinin receptor 3 2 2
MIRT459687 VPS37C VPS37C, ESCRT-I subunit 2 2
MIRT459914 HHIP hedgehog interacting protein 2 11
MIRT460610 FEM1A fem-1 homolog A 2 2
MIRT460646 IGFBP4 insulin like growth factor binding protein 4 2 2
MIRT461454 SLC19A3 solute carrier family 19 member 3 2 2
MIRT461909 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462059 CCDC77 coiled-coil domain containing 77 2 4
MIRT462404 RBM28 RNA binding motif protein 28 2 2
MIRT462589 MYL12A myosin light chain 12A 2 2
MIRT462770 ZNF8 zinc finger protein 8 2 2
MIRT462991 ZNF740 zinc finger protein 740 2 2
MIRT463680 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT464112 VPS35 VPS35, retromer complex component 2 2
MIRT464414 UNC13A unc-13 homolog A 2 6
MIRT464608 UBE4B ubiquitination factor E4B 2 2
MIRT465679 TNPO2 transportin 2 2 2
MIRT467225 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT469316 RGP1 RGP1 homolog, RAB6A GEF complex partner 1 2 2
MIRT469604 RALGAPA2 Ral GTPase activating protein catalytic alpha subunit 2 2 2
MIRT469655 RAC1 Rac family small GTPase 1 2 2
MIRT469744 RAB2B RAB2B, member RAS oncogene family 2 2
MIRT469947 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT470140 PSME3 proteasome activator subunit 3 2 2
MIRT473142 MLLT1 MLLT1, super elongation complex subunit 2 2
MIRT473287 MFRP membrane frizzled-related protein 2 2
MIRT473379 MBD4 methyl-CpG binding domain 4, DNA glycosylase 2 6
MIRT473661 MARCKSL1 MARCKS like 1 2 2
MIRT475256 IGF1R insulin like growth factor 1 receptor 2 2
MIRT475361 ICOSLG inducible T-cell costimulator ligand 2 4
MIRT475662 HIC2 HIC ZBTB transcriptional repressor 2 2 2
MIRT476524 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT476572 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT477624 EFNA1 ephrin A1 2 2
MIRT478125 DIRAS1 DIRAS family GTPase 1 2 2
MIRT479971 CARD10 caspase recruitment domain family member 10 2 2
MIRT480144 CALR calreticulin 2 2
MIRT480349 C5orf24 chromosome 5 open reading frame 24 2 2
MIRT480402 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT480741 BNC2 basonuclin 2 2 8
MIRT481987 AMOTL2 angiomotin like 2 2 2
MIRT482650 FAM195B MAPK regulated corepressor interacting protein 1 2 4
MIRT482809 TRAF6 TNF receptor associated factor 6 2 2
MIRT482945 ZNF561 zinc finger protein 561 2 6
MIRT482987 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT483123 ONECUT3 one cut homeobox 3 2 4
MIRT483253 CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 2 4
MIRT483580 SLC26A9 solute carrier family 26 member 9 2 2
MIRT483704 ASPH aspartate beta-hydroxylase 2 2
MIRT483932 LENG8 leukocyte receptor cluster member 8 2 4
MIRT484140 LRRC45 leucine rich repeat containing 45 2 4
MIRT484195 SUMO1 small ubiquitin-like modifier 1 2 4
MIRT484353 GATA6 GATA binding protein 6 2 12
MIRT484472 DDX6 DEAD-box helicase 6 2 2
MIRT484544 BARHL1 BarH like homeobox 1 2 6
MIRT484572 HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2 2
MIRT485265 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT485376 MSN moesin 2 4
MIRT485763 B4GALT5 beta-1,4-galactosyltransferase 5 2 2
MIRT485882 AGO2 argonaute 2, RISC catalytic component 2 17
MIRT486242 FASTK Fas activated serine/threonine kinase 2 2
MIRT486431 NDUFA5 NADH:ubiquinone oxidoreductase subunit A5 2 2
MIRT486569 ZNF619 zinc finger protein 619 2 2
MIRT486608 METTL6 methyltransferase like 6 2 2
MIRT487442 TFAP2B transcription factor AP-2 beta 2 4
MIRT487577 FAM83H family with sequence similarity 83 member H 2 4
MIRT487812 PER3 period circadian clock 3 2 2
MIRT487944 ISCA1 iron-sulfur cluster assembly 1 2 2
MIRT487952 IQSEC2 IQ motif and Sec7 domain 2 2 2
MIRT488011 GDF5OS growth differentiation factor 5 opposite strand 2 2
MIRT488311 LDOC1 LDOC1, regulator of NFKB signaling 2 2
MIRT488639 HAND2 heart and neural crest derivatives expressed 2 2 2
MIRT488651 ELAVL3 ELAV like RNA binding protein 3 2 2
MIRT488683 NAT9 N-acetyltransferase 9 (putative) 2 2
MIRT488846 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT488970 REXO2 RNA exonuclease 2 2 2
MIRT489002 FBXO40 F-box protein 40 2 2
MIRT489038 PRPF4B pre-mRNA processing factor 4B 2 2
MIRT489167 ANKRD45 ankyrin repeat domain 45 2 2
MIRT489221 ASCL2 achaete-scute family bHLH transcription factor 2 2 4
MIRT489356 SYNGR1 synaptogyrin 1 2 4
MIRT489373 RAB11B RAB11B, member RAS oncogene family 2 6
MIRT489526 MRE11A MRE11 homolog, double strand break repair nuclease 2 14
MIRT490071 PRRT2 proline rich transmembrane protein 2 2 2
MIRT490275 ZNF562 zinc finger protein 562 2 4
MIRT490696 FSTL4 follistatin like 4 2 2
MIRT490778 PSMD3 proteasome 26S subunit, non-ATPase 3 2 2
MIRT490854 UPK2 uroplakin 2 2 2
MIRT491048 CHST12 carbohydrate sulfotransferase 12 2 2
MIRT491123 PTPRE protein tyrosine phosphatase, receptor type E 2 2
MIRT491161 LRP3 LDL receptor related protein 3 2 2
MIRT491506 CREBL2 cAMP responsive element binding protein like 2 2 2
MIRT491532 HDAC5 histone deacetylase 5 2 2
MIRT491699 PDZD4 PDZ domain containing 4 2 2
MIRT491949 VPS52 VPS52, GARP complex subunit 2 2
MIRT492226 SLC48A1 solute carrier family 48 member 1 2 2
MIRT492278 SHISA6 shisa family member 6 2 4
MIRT492472 RASD1 ras related dexamethasone induced 1 2 4
MIRT492480 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT492498 RANBP10 RAN binding protein 10 2 4
MIRT492565 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 2
MIRT492702 PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2 2
MIRT492916 NFAT5 nuclear factor of activated T-cells 5 2 2
MIRT493020 NACC1 nucleus accumbens associated 1 2 2
MIRT493218 MEX3A mex-3 RNA binding family member A 2 2
MIRT493313 LIMD2 LIM domain containing 2 2 2
MIRT493410 KDM6B lysine demethylase 6B 2 2
MIRT493451 ITFG3 family with sequence similarity 234 member A 2 2
MIRT494028 DUSP7 dual specificity phosphatase 7 2 4
MIRT494329 CASKIN1 CASK interacting protein 1 2 2
MIRT496564 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT496771 ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif 14 2 2
MIRT496973 RPS6KA2 ribosomal protein S6 kinase A2 2 2
MIRT497038 DYRK1B dual specificity tyrosine phosphorylation regulated kinase 1B 2 2
MIRT498913 SRCAP Snf2 related CREBBP activator protein 2 2
MIRT499006 CCDC50 coiled-coil domain containing 50 2 2
MIRT499637 CREB3L2 cAMP responsive element binding protein 3 like 2 2 2
MIRT501700 PCGF3 polycomb group ring finger 3 2 6
MIRT502230 HOXC6 homeobox C6 2 2
MIRT502655 CTC1 CST telomere replication complex component 1 2 13
MIRT506246 PER1 period circadian clock 1 2 8
MIRT506430 NAGK N-acetylglucosamine kinase 2 6
MIRT507336 FAM168A family with sequence similarity 168 member A 2 2
MIRT507781 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT510062 C12orf49 chromosome 12 open reading frame 49 2 4
MIRT511935 FAM127B retrotransposon Gag like 8A 2 2
MIRT513037 BRIX1 BRX1, biogenesis of ribosomes 2 2
MIRT513518 YIPF4 Yip1 domain family member 4 2 6
MIRT522612 MAP7D1 MAP7 domain containing 1 2 4
MIRT527162 ADRA2B adrenoceptor alpha 2B 2 2
MIRT535350 PFN1 profilin 1 2 2
MIRT536734 IER5 immediate early response 5 2 4
MIRT538505 CLIP1 CAP-Gly domain containing linker protein 1 2 2
MIRT544643 PHF8 PHD finger protein 8 2 4
MIRT544856 MYH2 myosin heavy chain 2 2 4
MIRT568898 ATP6V1B1 ATPase H+ transporting V1 subunit B1 2 2
MIRT568949 RUNX3 runt related transcription factor 3 2 2
MIRT568971 CACNA1C calcium voltage-gated channel subunit alpha1 C 2 2
MIRT569037 IL21R interleukin 21 receptor 2 2
MIRT569310 CC2D1B coiled-coil and C2 domain containing 1B 2 2
MIRT569721 GPR173 G protein-coupled receptor 173 2 2
MIRT569765 SAMD14 sterile alpha motif domain containing 14 2 2
MIRT569857 KRT80 keratin 80 2 2
MIRT569867 KLK10 kallikrein related peptidase 10 2 2
MIRT569914 PCSK9 proprotein convertase subtilisin/kexin type 9 2 2
MIRT570060 CPNE2 copine 2 2 2
MIRT570307 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT570982 RGS19 regulator of G protein signaling 19 2 2
MIRT571025 CLSTN1 calsyntenin 1 2 2
MIRT573215 NAT10 N-acetyltransferase 10 2 2
MIRT574633 LPCAT3 lysophosphatidylcholine acyltransferase 3 2 2
MIRT574690 HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 2 2
MIRT575732 Hhip Hedgehog-interacting protein 2 7
MIRT575837 Ago2 argonaute RISC catalytic subunit 2 2 10
MIRT631303 CBS cystathionine-beta-synthase 2 2
MIRT647750 SAMD9L sterile alpha motif domain containing 9 like 2 2
MIRT648323 PLIN1 perilipin 1 2 2
MIRT649339 HEXA hexosaminidase subunit alpha 2 2
MIRT649994 MSI1 musashi RNA binding protein 1 2 2
MIRT661786 NLRC3 NLR family CARD domain containing 3 2 2
MIRT665992 SYNJ2BP synaptojanin 2 binding protein 2 2
MIRT667177 NR2F6 nuclear receptor subfamily 2 group F member 6 2 4
MIRT667386 MOB1B MOB kinase activator 1B 2 2
MIRT680929 EVC EvC ciliary complex subunit 1 2 2
MIRT691870 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT693258 HBS1L HBS1 like translational GTPase 2 2
MIRT693490 MOB3A MOB kinase activator 3A 2 2
MIRT696099 SETD1A SET domain containing 1A 2 2
MIRT697955 TSPYL1 TSPY like 1 2 2
MIRT699481 SLC10A6 solute carrier family 10 member 6 2 2
MIRT708274 ZNF101 zinc finger protein 101 2 2
MIRT712147 TAOK1 TAO kinase 1 2 2
MIRT717122 SOWAHA sosondowah ankyrin repeat domain family member A 2 2
MIRT717643 HLX H2.0 like homeobox 2 2
MIRT755336 DCAF1 DDB1 and CUL4 associated factor 1 6 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-3175 Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer cell line (BGC823)
hsa-mir-3175 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-3175 Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (SKOV3)
hsa-miR-3175 Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-miR-3175 Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780)
hsa-miR-3175 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PATU8988)
hsa-miR-3175 Vemurafenib 42611257 NSC761431 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3175 Dabrafenib 44462760 NSC764134 approved sensitive High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-3175 Cisplatin 5460033 NSC119875 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-3175 Temozolomide 5394 NSC362856 approved sensitive High Glioblastoma cell line (U251)
hsa-mir-3175 Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-3175 Cisplatin 5460033 NSC119875 approved sensitive cell line (W1)
hsa-mir-3175 Doxorubicin 31703 NSC123127 approved sensitive cell line (W1)
hsa-mir-3175 Tamoxifen 2733525 NSC180973 approved resistant cell line (MCF7)
hsa-mir-3175 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-mir-3175 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-mir-3175 Cisplatin 5460033 NSC119875 approved sensitive cell line (BGC-823)
hsa-miR-3175 Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-3175 Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-3175 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM17)
hsa-miR-3175 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM47)
hsa-miR-3175 Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-3175 Doxorubicin 31703 NSC123127 approved sensitive cell line (BAS)
hsa-miR-3175 Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-3175 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-3175 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3175 Neoadjuvant chemotherapy resistant tissue (breast cancer)

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