miRTarBase - #MIRT271675


—
pre-miRNA Information
pre-miRNA hsa-mir-514b   
Genomic Coordinates chrX: 147250151 - 147250230
Description Homo sapiens miR-514b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-514b-5p
Sequence 13| UUCUCAAGAGGGAGGCAAUCAU |34
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1260150563 12 dbSNP
rs1440758764 15 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SDE2   
Synonyms C1orf55, dJ671D7.1
Description SDE2 telomere maintenance homolog
Transcript NM_152608   
Expression
Putative miRNA Targets on SDE2
3'UTR of SDE2
(miRNA target sites are highlighted)		 
>SDE2|NM_152608|3'UTR
   1 GTATCATCAGAGCTGATTCCTATTTGTTTATAGTGTCTACCATTTACAACCTGCATAATGTGGACTCTTGACCAGTATTC
  81 CTGTTGATATTAAAAGCTAACTTTTTAGTAACCCAATTCTAACTATCCCCTTTTTCCTTGTCAGGGCTGTAGAATTAATG
 161 TCTGAAACCATCTGGGCCTTAAATTTTCTTTGTCTGGTTTTCTATAGTGTATTTAATAAATATAGGGCTATTCACATTTT
 241 TTGGTTTGATCTTGGTGTCATTTAGGTAATGAATCTATCCAAGAAATCTATCCTTTTGACCCAGGTTATCAAATTTGTAG
 321 ACATAAGGTTATTTATAATGGTCCCTTCTTACCCTTTTAATGTCTTTAGGAGCTGTGTTGATAATTTCCTTTTCATTATG
 401 ATACTGGTAATTTCTGTTCTCACTTTCCTAATCAGGTTGGGTAGGGGTTTATCAGTTTTACTGATCTGACTTTTTATTTT
 481 ATTTTATTTTTTTTGAGACAGTCTTACACTGTCTCCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTTACTGCAAGCTCT
 561 GCCTTCCGGGTTCATGCCATTCTCCTGCCTCAGCCTCCCCAGTAGCTGGGACTACAGGCTCCCACCACCACGCCCGGCTA
 641 ATTTTTTATATTTTTAGTGGAGACTGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCTCTTTACCTCGTGGTCCACCC
 721 GCCTCAGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCTGGCCGACGATATAACTTTTAAAGAACCAACC
 801 TTTGGTTTTATTTTTCTCAATTGTTTATATAATTAATTTCTGTTATTTTCTTTCTTCTATTTAGCTTGAGTCTCCTTTGA
 881 TCTTTTTTCTTTAGTTCCTTAAGATAAGCCTTAGGTCATTGATCTTAGACGTTATTTAAAATACATATTTAAAGCTATAC
 961 ATTTTCTTTTAAGCATTACTTTAGTTGCGACTTTACAATTTTATTATGTCGTATTTTTATTATTCAGTTCTAATTTTCTT
1041 TTTTTTTTCTTTTTGAGATGGAATTTCGCTTTTGTTGCCCAGGCTAGAGTGCAATGGTACGATCTCAGCTCACTGCAACC
1121 TCTGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTCAGTAGCTGGGATTACAGGCTCCAGCCACCATACCTGG
1201 CTGATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCACATTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCC
1281 ACCCACTTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCCAGCCTCTGATTATTTTCTAATTTCCTC
1361 CCTCAGTTCTTCTTTGACCCATGGATTATCAGAAGTGGGTTGTCTGATCAGCAAACATTTGTTTTTTTTCCTCTTAATAT
1441 CTTCTTGTTGCTGATTTCTACTTTAATTCCATTGAGGTCAGAAAATATCCTCTTTATGATTTCAATCCTCTTAGTTTTAT
1521 TGAGACTCGTTTTATGACCCAATATGTTGTCTGTCATGGTGAGTGTACCATACACAGTTTAAAAGAATGCGTATTTTAGG
1601 CCAGGTGTGGTGGCTCATGCCTGTAATCCAGCATGAGATTACATGCTGAGATTACAGCTGTAATCTGTAATTTGAGAGGC
1681 TGAGGTGGGAGGATCATTTCGAGACCAGCCTGGGCAATGTATAGTGAGACCATGTCTCTAAGAAAAACAATATGTAATTT
1761 GAATTGTTGGGTTAATATGTTTTGTAATATCGATGAGATTAAGTGGTTGATAGTATTGTTCAGATCTTCTATGTCTTTAC
1841 TGATCCTTTTGTTTATTTCTATCAGGTGCTGAGAAAGGATGTTAAAATCTTCAATTATGATTGTGGAATTGTCTATTTCT
1921 TAAATTCTACCAGTTTTTGTATGAAGCTCTAATAACTTATGTCTTCCTAATGTATTGACCATTTTATCATTATGAAATTT
2001 CCCTCTGTCTCTGGTAATTTGGGTTTGAAATCTACTTTATCTTATGTGAATATAGCCACTGCAGCCTTCTTAAGCTTAGT
2081 GTTTGCACAGTATACCTCTTTCTATTAATTTACTTTGTGCTTCTGTGCCTATTTAAAGTAGTTTCTTTAAACAACATATA
2161 CTTGAGACTTGCATTTTTATCTGTTCTCTCTGTATCTTTTAATAAGTTTAACATTAAATGTAATTATTAATAGGTTTCTA
2241 ATTTACATGTTTCCTGTTTAGATAAGATTATTTTATAATTGTATTTTAATTTATTGGCTCTTTAGCTATACTGTTTTAAT
2321 AATTTTTTTAAGTTGGATGTTCTAGTGATTACAATATACATTCTTAATTTTTCAGTCTACCTAGAGTTGATGTGCCACTT
2401 CACATAAAATGTAGAAATCTTGTAAGTATGTACATCCATTTATCATACCTGTCTTTTATGCTGTAGTTGTCATACATATT
2481 AAATCTACATATTTAAATATTGTAAGTCCTGTCATAAGTTACAATTTCTGCTTTAAATAATGATATGTATTTTAAAGAAA
2561 TTAAGAGGAAAAAATAAAATCTTTTGTATTTATTCACATAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uacuAACGGAGGGAGAACUCUu 5'
              || ::|:|:|:|||||| 
Target 5' ctttTTTTTTTCTTTTTGAGAt 3'
 1038 - 1059 150.00 -13.20
2 
miRNA  3' uacUAACGGAGGGAGAACUCUu 5'
             ||| : |:::|:|||||| 
Target 5' tttATTTTATTTTTTTTGAGAc 3'
 478 - 499 147.00 -8.80
3 
miRNA  3' uacuaacggagggaGAACUCUu 5'
                        ||||||| 
Target 5' ttaaacaacatataCTTGAGAc 3'
 2147 - 2168 140.00 -7.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30570694 2 COSMIC
COSN31552912 33 COSMIC
COSN30487374 41 COSMIC
COSN30138804 60 COSMIC
COSN9060664 90 COSMIC
COSN30510931 131 COSMIC
COSN30526753 140 COSMIC
COSN26222435 353 COSMIC
COSN21330565 842 COSMIC
COSN8436242 1040 COSMIC
COSN8436241 1731 COSMIC
COSN15833227 1791 COSMIC
COSN1434095 2308 COSMIC
COSN8436240 2332 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs751678343 3 dbSNP
rs1237620069 4 dbSNP
rs1348119039 7 dbSNP
rs1286946185 8 dbSNP
rs746882202 16 dbSNP
rs989797061 19 dbSNP
rs1351453660 20 dbSNP
rs777570740 22 dbSNP
rs556653094 23 dbSNP
rs1440315197 25 dbSNP
rs1393066472 30 dbSNP
rs752648095 32 dbSNP
rs889637392 37 dbSNP
rs200544214 39 dbSNP
rs755086843 42 dbSNP
rs773259670 46 dbSNP
rs753982107 48 dbSNP
rs766679741 49 dbSNP
rs1413134013 57 dbSNP
rs998278065 64 dbSNP
rs981301037 75 dbSNP
rs1307675813 81 dbSNP
rs1333517535 96 dbSNP
rs971605313 97 dbSNP
rs1256245186 99 dbSNP
rs1023062614 100 dbSNP
rs1343769140 106 dbSNP
rs574441323 114 dbSNP
rs1259820377 116 dbSNP
rs1458030994 119 dbSNP
rs1197981102 123 dbSNP
rs1248280366 127 dbSNP
rs1199597858 132 dbSNP
rs898568231 136 dbSNP
rs1016921406 153 dbSNP
rs901250284 158 dbSNP
rs1401540635 162 dbSNP
rs1037479215 169 dbSNP
rs1004163131 175 dbSNP
rs888723034 176 dbSNP
rs887404113 191 dbSNP
rs1277019278 197 dbSNP
rs1397661812 200 dbSNP
rs1388018572 202 dbSNP
rs551766707 204 dbSNP
rs1299345430 208 dbSNP
rs1221361497 211 dbSNP
rs938240314 216 dbSNP
rs553154665 223 dbSNP
rs1197726372 225 dbSNP
rs534712926 233 dbSNP
rs982213021 260 dbSNP
rs1210354077 262 dbSNP
rs1357804748 267 dbSNP
rs1178752936 268 dbSNP
rs1196165713 269 dbSNP
rs1424551136 270 dbSNP
rs571018611 271 dbSNP
rs147593112 274 dbSNP
rs1423262400 287 dbSNP
rs917004111 293 dbSNP
rs1458921250 304 dbSNP
rs537318739 305 dbSNP
rs943121799 317 dbSNP
rs1402511248 319 dbSNP
rs1299681587 327 dbSNP
rs1340685752 327 dbSNP
rs964827871 328 dbSNP
rs570356544 333 dbSNP
rs1245491200 336 dbSNP
rs773631917 341 dbSNP
rs1482915998 344 dbSNP
rs1357408518 348 dbSNP
rs1235496654 359 dbSNP
rs772419941 360 dbSNP
rs934276204 367 dbSNP
rs1264183248 371 dbSNP
rs1488126860 375 dbSNP
rs924559392 388 dbSNP
rs1184989530 394 dbSNP
rs76843836 400 dbSNP
rs1424733084 404 dbSNP
rs1383878690 407 dbSNP
rs1422229286 409 dbSNP
rs971274476 423 dbSNP
rs1360599430 437 dbSNP
rs142542568 440 dbSNP
rs184242613 441 dbSNP
rs1381123982 442 dbSNP
rs1396350779 443 dbSNP
rs1314318652 447 dbSNP
rs998015862 449 dbSNP
rs549072708 454 dbSNP
rs962804229 466 dbSNP
rs547438421 481 dbSNP
rs531159412 486 dbSNP
rs1257943006 487 dbSNP
rs1015663975 491 dbSNP
rs951422435 491 dbSNP
rs766791786 495 dbSNP
rs1442159971 499 dbSNP
rs748713616 502 dbSNP
rs762051119 506 dbSNP
rs1304955125 507 dbSNP
rs778839030 511 dbSNP
rs1399749898 515 dbSNP
rs531881153 517 dbSNP
rs1048344082 518 dbSNP
rs149192547 523 dbSNP
rs531261502 529 dbSNP
rs1011071244 535 dbSNP
rs1372742142 536 dbSNP
rs892895164 537 dbSNP
rs530691485 538 dbSNP
rs1312926001 544 dbSNP
rs1411613530 544 dbSNP
rs1203269226 545 dbSNP
rs768766768 548 dbSNP
rs563643225 555 dbSNP
rs949561781 559 dbSNP
rs370530700 567 dbSNP
rs145378495 568 dbSNP
rs61835211 580 dbSNP
rs1251351084 582 dbSNP
rs988592611 585 dbSNP
rs1243516413 592 dbSNP
rs1320429319 593 dbSNP
rs934384078 594 dbSNP
rs1433475050 595 dbSNP
rs915824684 599 dbSNP
rs61835210 600 dbSNP
rs1403690990 604 dbSNP
rs991323951 608 dbSNP
rs150033284 614 dbSNP
rs756329542 627 dbSNP
rs982799550 631 dbSNP
rs951430211 635 dbSNP
rs1030099186 636 dbSNP
rs1368381816 644 dbSNP
rs1223182196 646 dbSNP
rs978414906 647 dbSNP
rs1320481674 648 dbSNP
rs998183015 667 dbSNP
rs1449243808 677 dbSNP
rs964679651 678 dbSNP
rs1018534825 680 dbSNP
rs1436508708 683 dbSNP
rs1224419627 691 dbSNP
rs192567859 695 dbSNP
rs187567406 696 dbSNP
rs1456470336 709 dbSNP
rs1347976921 710 dbSNP
rs1165426782 713 dbSNP
rs1408197355 715 dbSNP
rs1418524962 715 dbSNP
rs1001037236 717 dbSNP
rs577036403 720 dbSNP
rs558862746 721 dbSNP
rs1054225662 731 dbSNP
rs551830149 737 dbSNP
rs902921386 739 dbSNP
rs1015818111 744 dbSNP
rs1004301496 748 dbSNP
rs1270047865 749 dbSNP
rs537686044 752 dbSNP
rs759000487 753 dbSNP
rs1230573047 754 dbSNP
rs182862864 758 dbSNP
rs1359565720 759 dbSNP
rs894402106 763 dbSNP
rs1055600109 764 dbSNP
rs1026978684 771 dbSNP
rs1241356130 773 dbSNP
rs1474285313 776 dbSNP
rs941209478 777 dbSNP
rs1267706280 778 dbSNP
rs116049995 780 dbSNP
rs1046619307 781 dbSNP
rs116538901 782 dbSNP
rs1400899436 787 dbSNP
rs372593019 790 dbSNP
rs1450578937 791 dbSNP
rs1242847525 795 dbSNP
rs922702057 799 dbSNP
rs1300856447 814 dbSNP
rs547399723 814 dbSNP
rs146386773 825 dbSNP
rs571434678 826 dbSNP
rs925689409 830 dbSNP
rs143612910 831 dbSNP
rs1018551222 833 dbSNP
rs71646758 843 dbSNP
rs1283068604 845 dbSNP
rs989707815 846 dbSNP
rs760493888 850 dbSNP
rs750695122 854 dbSNP
rs1181663000 855 dbSNP
rs1359896214 857 dbSNP
rs1156598099 859 dbSNP
rs1382297429 859 dbSNP
rs1454342182 859 dbSNP
rs1382998878 860 dbSNP
rs1416525771 861 dbSNP
rs958258608 882 dbSNP
rs1335355110 889 dbSNP
rs1031205178 897 dbSNP
rs999694014 900 dbSNP
rs1363951763 905 dbSNP
rs1378511707 908 dbSNP
rs149041991 909 dbSNP
rs902973136 909 dbSNP
rs1348012528 925 dbSNP
rs1201810982 926 dbSNP
rs1024021137 929 dbSNP
rs1014343232 930 dbSNP
rs530783117 931 dbSNP
rs894114305 939 dbSNP
rs1268802076 940 dbSNP
rs1239884485 941 dbSNP
rs1055655188 943 dbSNP
rs1488244722 947 dbSNP
rs1181099710 948 dbSNP
rs908380850 961 dbSNP
rs1177392890 963 dbSNP
rs1429076751 970 dbSNP
rs1284523809 971 dbSNP
rs1468526561 971 dbSNP
rs983016043 974 dbSNP
rs1401587537 975 dbSNP
rs1391468107 984 dbSNP
rs941304453 988 dbSNP
rs376788413 989 dbSNP
rs1255575257 998 dbSNP
rs1231304038 1008 dbSNP
rs1002189237 1010 dbSNP
rs115533329 1011 dbSNP
rs929822843 1012 dbSNP
rs192301222 1023 dbSNP
rs976834468 1024 dbSNP
rs1195142886 1025 dbSNP
rs1296270736 1030 dbSNP
rs1248570721 1034 dbSNP
rs1200459550 1043 dbSNP
rs879627322 1043 dbSNP
rs559363290 1044 dbSNP
rs1479668104 1045 dbSNP
rs541055511 1048 dbSNP
rs1173189003 1049 dbSNP
rs1461970903 1049 dbSNP
rs892702542 1049 dbSNP
rs942696744 1052 dbSNP
rs1052656041 1055 dbSNP
rs911250111 1055 dbSNP
rs1393741630 1058 dbSNP
rs1406197331 1062 dbSNP
rs1001422384 1066 dbSNP
rs1464227775 1067 dbSNP
rs140005759 1068 dbSNP
rs958311935 1076 dbSNP
rs150643022 1086 dbSNP
rs1307838286 1088 dbSNP
rs1226657098 1089 dbSNP
rs141866182 1093 dbSNP
rs970888759 1094 dbSNP
rs1195978839 1096 dbSNP
rs1024486366 1100 dbSNP
rs1041074685 1101 dbSNP
rs1013979976 1102 dbSNP
rs1255864294 1108 dbSNP
rs1262923661 1111 dbSNP
rs894208997 1118 dbSNP
rs1428254037 1121 dbSNP
rs1191701566 1127 dbSNP
rs1199163600 1131 dbSNP
rs1370648597 1132 dbSNP
rs1484351302 1136 dbSNP
rs1264002854 1140 dbSNP
rs1034003721 1141 dbSNP
rs576532118 1145 dbSNP
rs1316176261 1147 dbSNP
rs1364397627 1150 dbSNP
rs554873808 1152 dbSNP
rs1290236357 1158 dbSNP
rs944004847 1161 dbSNP
rs536512749 1168 dbSNP
rs1362438594 1173 dbSNP
rs908454131 1174 dbSNP
rs1293365294 1182 dbSNP
rs1342120863 1194 dbSNP
rs888402480 1197 dbSNP
rs1327023762 1199 dbSNP
rs1291204998 1200 dbSNP
rs2755101 1203 dbSNP
rs1261489621 1218 dbSNP
rs188419824 1232 dbSNP
rs182914314 1233 dbSNP
rs1258701199 1235 dbSNP
rs994419869 1236 dbSNP
rs1394087359 1237 dbSNP
rs900982254 1240 dbSNP
rs1183493436 1241 dbSNP
rs1041259530 1242 dbSNP
rs1384113588 1243 dbSNP
rs1337022350 1257 dbSNP
rs969406269 1260 dbSNP
rs1345354918 1264 dbSNP
rs942791771 1269 dbSNP
rs1452792602 1283 dbSNP
rs111766307 1290 dbSNP
rs911303807 1298 dbSNP
rs1024964653 1299 dbSNP
rs1053827893 1307 dbSNP
rs936619785 1309 dbSNP
rs1314249828 1312 dbSNP
rs924198508 1312 dbSNP
rs144568055 1313 dbSNP
rs1476023144 1322 dbSNP
rs971320511 1331 dbSNP
rs1368452966 1336 dbSNP
rs142795418 1341 dbSNP
rs990933125 1348 dbSNP
rs138953356 1352 dbSNP
rs1029124735 1358 dbSNP
rs1243931444 1362 dbSNP
rs1203622340 1375 dbSNP
rs1241786414 1379 dbSNP
rs996604381 1380 dbSNP
rs1034059148 1381 dbSNP
rs899577170 1400 dbSNP
rs765635963 1404 dbSNP
rs1418203137 1412 dbSNP
rs1005177039 1414 dbSNP
rs1431213719 1419 dbSNP
rs1470087837 1421 dbSNP
rs1403734288 1422 dbSNP
rs952347842 1429 dbSNP
rs1298878048 1430 dbSNP
rs1395227970 1430 dbSNP
rs1372674331 1433 dbSNP
rs1026000752 1436 dbSNP
rs751553914 1447 dbSNP
rs1285390357 1462 dbSNP
rs1324748322 1464 dbSNP
rs1223223806 1468 dbSNP
rs1456641725 1472 dbSNP
rs1440120006 1477 dbSNP
rs763691620 1485 dbSNP
rs1205815667 1490 dbSNP
rs762608964 1492 dbSNP
rs146091318 1498 dbSNP
rs1175150260 1504 dbSNP
rs931207917 1505 dbSNP
rs1480647184 1507 dbSNP
rs1339934408 1508 dbSNP
rs190738824 1510 dbSNP
rs948177512 1511 dbSNP
rs1171022897 1513 dbSNP
rs1354046489 1524 dbSNP
rs1242293073 1526 dbSNP
rs6664468 1528 dbSNP
rs1346316223 1536 dbSNP
rs1315524755 1540 dbSNP
rs1341878869 1541 dbSNP
rs992200251 1544 dbSNP
rs1445537022 1545 dbSNP
rs1053839570 1551 dbSNP
rs1272872828 1555 dbSNP
rs936671742 1571 dbSNP
rs764916462 1572 dbSNP
rs923939475 1573 dbSNP
rs759264875 1580 dbSNP
rs956933842 1585 dbSNP
rs1202332420 1586 dbSNP
rs1042760809 1587 dbSNP
rs1293317344 1589 dbSNP
rs529994459 1590 dbSNP
rs949688428 1591 dbSNP
rs1198213617 1595 dbSNP
rs1330291972 1600 dbSNP
rs1410052921 1609 dbSNP
rs1030976413 1614 dbSNP
rs1476250487 1617 dbSNP
rs980093553 1621 dbSNP
rs918155011 1629 dbSNP
rs1408283559 1631 dbSNP
rs371319156 1631 dbSNP
rs990986863 1633 dbSNP
rs1029198218 1638 dbSNP
rs559719346 1640 dbSNP
rs996345201 1644 dbSNP
rs1424313625 1645 dbSNP
rs1301486238 1659 dbSNP
rs959492015 1664 dbSNP
rs547408585 1665 dbSNP
rs776441530 1666 dbSNP
rs1270140812 1667 dbSNP
rs983812229 1668 dbSNP
rs1360407730 1671 dbSNP
rs74148409 1678 dbSNP
rs1293381760 1681 dbSNP
rs529438139 1683 dbSNP
rs994230259 1691 dbSNP
rs1178484536 1695 dbSNP
rs76220707 1700 dbSNP
rs1234829709 1708 dbSNP
rs1019502312 1725 dbSNP
rs1006734940 1730 dbSNP
rs1241305077 1732 dbSNP
rs760262090 1734 dbSNP
rs1182535908 1736 dbSNP
rs1185320449 1743 dbSNP
rs1451145393 1744 dbSNP
rs772538900 1747 dbSNP
rs889592959 1749 dbSNP
rs1046690738 1756 dbSNP
rs1161927773 1758 dbSNP
rs1387340641 1761 dbSNP
rs1289003119 1772 dbSNP
rs1220124977 1775 dbSNP
rs1318155311 1778 dbSNP
rs1343782535 1784 dbSNP
rs1455092579 1791 dbSNP
rs1316297419 1792 dbSNP
rs1382919459 1799 dbSNP
rs762197975 1807 dbSNP
rs1361549171 1809 dbSNP
rs931239238 1818 dbSNP
rs375836867 1824 dbSNP
rs1283352697 1827 dbSNP
rs1463349857 1829 dbSNP
rs1000976718 1831 dbSNP
rs1205512342 1831 dbSNP
rs1044897053 1839 dbSNP
rs1185425570 1861 dbSNP
rs561502899 1864 dbSNP
rs1280929066 1872 dbSNP
rs1158181244 1886 dbSNP
rs1406282515 1892 dbSNP
rs1442249582 1893 dbSNP
rs1042427214 1894 dbSNP
rs1337981240 1898 dbSNP
rs1405913258 1902 dbSNP
rs560361551 1902 dbSNP
rs917727043 1905 dbSNP
rs949413003 1911 dbSNP
rs1331699351 1912 dbSNP
rs117173944 1915 dbSNP
rs1055270084 1930 dbSNP
rs1239366915 1933 dbSNP
rs767129192 1940 dbSNP
rs186169822 1942 dbSNP
rs909408386 1944 dbSNP
rs979418159 1947 dbSNP
rs968330100 1948 dbSNP
rs922161636 1949 dbSNP
rs768713567 1953 dbSNP
rs1249823845 1954 dbSNP
rs1158359924 1960 dbSNP
rs1429017164 1961 dbSNP
rs1418262876 1962 dbSNP
rs1410392958 1966 dbSNP
rs1398044055 1968 dbSNP
rs749312218 1975 dbSNP
rs1327781157 1981 dbSNP
rs137859180 1992 dbSNP
rs1348168446 2001 dbSNP
rs775573970 2005 dbSNP
rs974936722 2027 dbSNP
rs966623779 2035 dbSNP
rs1231020623 2040 dbSNP
rs931111338 2044 dbSNP
rs769952112 2045 dbSNP
rs771850020 2059 dbSNP
rs972427005 2063 dbSNP
rs1195238759 2065 dbSNP
rs1008397830 2072 dbSNP
rs1200387201 2096 dbSNP
rs1490815817 2100 dbSNP
rs1431760364 2111 dbSNP
rs965380231 2113 dbSNP
rs1269533897 2114 dbSNP
rs1019554652 2125 dbSNP
rs951130503 2129 dbSNP
rs1374075222 2136 dbSNP
rs1462053734 2138 dbSNP
rs1167488230 2149 dbSNP
rs545301741 2151 dbSNP
rs746148364 2152 dbSNP
rs375088281 2161 dbSNP
rs1389778119 2178 dbSNP
rs1384807674 2179 dbSNP
rs1285856608 2181 dbSNP
rs1297646849 2183 dbSNP
rs1223971473 2186 dbSNP
rs1226592078 2194 dbSNP
rs1327026467 2194 dbSNP
rs150296379 2218 dbSNP
rs953927599 2221 dbSNP
rs182896360 2222 dbSNP
rs1245809164 2228 dbSNP
rs757141490 2229 dbSNP
rs1291245044 2246 dbSNP
rs1207195150 2264 dbSNP
rs1487715251 2264 dbSNP
rs1044972197 2265 dbSNP
rs1428500209 2267 dbSNP
rs1346624581 2271 dbSNP
rs573162911 2277 dbSNP
rs1387818408 2286 dbSNP
rs1445871439 2291 dbSNP
rs1398491532 2298 dbSNP
rs1012093693 2316 dbSNP
rs1456063312 2323 dbSNP
rs1001101170 2328 dbSNP
rs140237187 2329 dbSNP
rs1056266109 2330 dbSNP
rs1160333883 2336 dbSNP
rs554788689 2337 dbSNP
rs1385111973 2338 dbSNP
rs1246725458 2339 dbSNP
rs1314633322 2342 dbSNP
rs935447518 2354 dbSNP
rs924045958 2361 dbSNP
rs1261729935 2366 dbSNP
rs1485727817 2374 dbSNP
rs1013596921 2375 dbSNP
rs1207417228 2376 dbSNP
rs1245450021 2383 dbSNP
rs1462271699 2388 dbSNP
rs1183743302 2389 dbSNP
rs1043773555 2391 dbSNP
rs896449548 2398 dbSNP
rs1160806673 2404 dbSNP
rs1429857926 2410 dbSNP
rs1364192701 2411 dbSNP
rs1055322329 2417 dbSNP
rs938294427 2419 dbSNP
rs191058439 2422 dbSNP
rs1243631262 2429 dbSNP
rs773979023 2429 dbSNP
rs1216306985 2434 dbSNP
rs1302394390 2436 dbSNP
rs975010302 2444 dbSNP
rs896464122 2445 dbSNP
rs565977829 2448 dbSNP
rs1226872952 2453 dbSNP
rs1265380797 2455 dbSNP
rs547664704 2469 dbSNP
rs1324963022 2472 dbSNP
rs912056295 2475 dbSNP
rs983632041 2476 dbSNP
rs918349081 2479 dbSNP
rs972863904 2491 dbSNP
rs187180320 2492 dbSNP
rs181060320 2506 dbSNP
rs1250715053 2516 dbSNP
rs549532883 2516 dbSNP
rs371688054 2523 dbSNP
rs1025332559 2527 dbSNP
rs912257143 2540 dbSNP
rs1472143617 2542 dbSNP
rs1156763545 2543 dbSNP
rs995186572 2545 dbSNP
rs1175234019 2546 dbSNP
rs985113137 2546 dbSNP
rs953979533 2547 dbSNP
rs531411392 2557 dbSNP
rs1213296477 2561 dbSNP
rs1012584770 2562 dbSNP
rs1289798353 2564 dbSNP
rs1447776259 2565 dbSNP
rs1357573294 2567 dbSNP
rs1338977545 2568 dbSNP
rs896394471 2580 dbSNP
rs1056738829 2584 dbSNP
rs1470315611 2586 dbSNP
rs770737640 2595 dbSNP
rs979292921 2597 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uacuaacggagggaGAACUCuu 5'
                        ||||||  
Target 5' uuaaacaacauauaCUUGAG-- 3'
 		6 - 25
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000272091.7 | 3UTR | UUUCUUUAAACAACAUAUACUUGAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
101 hsa-miR-514b-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT106072 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT169586 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT259395 SLC6A8 solute carrier family 6 member 8 2 4
MIRT271675 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT286339 PHF12 PHD finger protein 12 2 2
MIRT334478 RPL27A ribosomal protein L27a 2 4
MIRT336467 SRP9 signal recognition particle 9 2 2
MIRT442118 KCNH5 potassium voltage-gated channel subfamily H member 5 2 2
MIRT462291 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT474679 KLF10 Kruppel like factor 10 2 2
MIRT475557 HNRNPF heterogeneous nuclear ribonucleoprotein F 2 2
MIRT479222 CKS2 CDC28 protein kinase regulatory subunit 2 2 2
MIRT496187 TECPR1 tectonin beta-propeller repeat containing 1 2 2
MIRT496811 CHRNB2 cholinergic receptor nicotinic beta 2 subunit 2 2
MIRT506493 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 4
MIRT509595 PEX26 peroxisomal biogenesis factor 26 2 4
MIRT512411 KIAA0391 KIAA0391 2 2
MIRT512439 SFTPB surfactant protein B 2 2
MIRT512581 ZNF223 zinc finger protein 223 2 2
MIRT525990 MAGEL2 MAGE family member L2 2 2
MIRT526427 PARP15 poly(ADP-ribose) polymerase family member 15 2 4
MIRT526772 DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 2 2
MIRT528090 UCHL3 ubiquitin C-terminal hydrolase L3 2 2
MIRT530438 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT532572 GSS glutathione synthetase 2 2
MIRT533990 SUZ12 SUZ12 polycomb repressive complex 2 subunit 2 2
MIRT534782 RAD23B RAD23 homolog B, nucleotide excision repair protein 2 2
MIRT536246 LPP LIM domain containing preferred translocation partner in lipoma 2 2
MIRT536471 KIAA1549L KIAA1549 like 2 2
MIRT538428 COL19A1 collagen type XIX alpha 1 chain 2 2
MIRT538839 BTG3 BTG anti-proliferation factor 3 2 2
MIRT539323 AHSA2 activator of HSP90 ATPase homolog 2 2 4
MIRT547012 PPP1R15B protein phosphatase 1 regulatory subunit 15B 2 2
MIRT551817 TMEM138 transmembrane protein 138 2 2
MIRT552910 VPS37A VPS37A, ESCRT-I subunit 2 2
MIRT553169 UBE2G1 ubiquitin conjugating enzyme E2 G1 2 2
MIRT553462 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT553551 TMEM161B transmembrane protein 161B 2 2
MIRT556253 MAPRE2 microtubule associated protein RP/EB family member 2 2 2
MIRT556874 ITGA2 integrin subunit alpha 2 2 2
MIRT558152 ELAVL2 ELAV like RNA binding protein 2 2 2
MIRT560320 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT564022 CEBPB CCAAT/enhancer binding protein beta 2 2
MIRT566386 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT569339 EFHC1 EF-hand domain containing 1 2 2
MIRT572595 PAPLN papilin, proteoglycan like sulfated glycoprotein 2 2
MIRT574178 TMPO thymopoietin 2 2
MIRT610592 NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit 2 2
MIRT615803 COQ7 coenzyme Q7, hydroxylase 2 2
MIRT616714 FEM1B fem-1 homolog B 2 2
MIRT617931 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT620333 SPAST spastin 2 2
MIRT620669 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT620711 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT622709 PLEKHA2 pleckstrin homology domain containing A2 2 2
MIRT623780 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT624111 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT626537 EMCN endomucin 2 2
MIRT630145 ZDHHC9 zinc finger DHHC-type containing 9 2 4
MIRT631638 WDR91 WD repeat domain 91 2 4
MIRT635122 RAD51 RAD51 recombinase 2 2
MIRT637461 DEFB105B defensin beta 105B 2 4
MIRT637493 DEFB105A defensin beta 105A 2 4
MIRT641197 TRIB1 tribbles pseudokinase 1 2 4
MIRT643396 PROM1 prominin 1 2 2
MIRT644889 ZBED1 zinc finger BED-type containing 1 2 2
MIRT647244 PTGDR2 prostaglandin D2 receptor 2 2 2
MIRT647528 CCDC121 coiled-coil domain containing 121 2 2
MIRT648395 WRN Werner syndrome RecQ like helicase 2 2
MIRT650121 G6PC glucose-6-phosphatase catalytic subunit 2 2
MIRT652355 TMEM92 transmembrane protein 92 2 2
MIRT653817 SIM2 single-minded family bHLH transcription factor 2 2 2
MIRT653943 SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 2 2
MIRT657290 HOXB5 homeobox B5 2 2
MIRT657826 GJD3 gap junction protein delta 3 2 2
MIRT658706 EMB embigin 2 2
MIRT658739 ELAVL4 ELAV like RNA binding protein 4 2 2
MIRT660175 BNC2 basonuclin 2 2 2
MIRT661323 TBC1D15 TBC1 domain family member 15 2 2
MIRT662205 PLA2G4E phospholipase A2 group IVE 2 2
MIRT662965 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT663876 CCDC65 coiled-coil domain containing 65 2 2
MIRT671779 RGS17 regulator of G protein signaling 17 2 2
MIRT673644 CYCS cytochrome c, somatic 2 2
MIRT675531 RPL37 ribosomal protein L37 2 2
MIRT676349 KLF8 Kruppel like factor 8 2 2
MIRT678427 PDE4C phosphodiesterase 4C 2 2
MIRT678484 ARHGEF39 Rho guanine nucleotide exchange factor 39 2 2
MIRT690846 PVR poliovirus receptor 2 2
MIRT691991 SGTB small glutamine rich tetratricopeptide repeat containing beta 2 2
MIRT698392 TMED10 transmembrane p24 trafficking protein 10 2 2
MIRT701264 NUP210 nucleoporin 210 2 2
MIRT703553 FKBP14 FK506 binding protein 14 2 2
MIRT711984 EXTL3 exostosin like glycosyltransferase 3 2 2
MIRT712653 PGAP3 post-GPI attachment to proteins 3 2 2
MIRT716759 TRABD2A TraB domain containing 2A 2 2
MIRT717931 ZFP64 ZFP64 zinc finger protein 2 2
MIRT718027 FAM163A family with sequence similarity 163 member A 2 2
MIRT718972 SPTSSA serine palmitoyltransferase small subunit A 2 2
MIRT721650 RPL34 ribosomal protein L34 2 2
MIRT724860 RIMBP2 RIMS binding protein 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-514b Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-miR-514b-5p Platinum 23939 resistant High Ovarian Cancer tissue
hsa-miR-514b-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-514b-5p Cisplatin 5460033 NSC119875 approved resistant Low Colorectal Cancer cell line (LOVO)
hsa-miR-514b-5p Irinotecan 60838 NSC728073 approved resistant Low Colorectal Cancer cell line (LOVO)
hsa-miR-514b-5p Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375)
hsa-miR-514b-5p Tripterygium wilfordii Hook F sensitive tissue
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM43)
hsa-miR-514b-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-514b-5p Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)

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