miRTarBase - #MIRT277519


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pre-miRNA Information
pre-miRNA hsa-mir-6833   
Genomic Coordinates chr6: 32179816 - 32179876
Description Homo sapiens miR-6833 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6833-5p
Sequence 6| GUGUGGAAGAUGGGAGGAGAAA |27
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs764873407 1 dbSNP
rs1232535042 3 dbSNP
rs574738502 14 dbSNP
Putative Targets

Gene Information
Gene Symbol PPP2R5C   
Synonyms B56G, B56gamma, PR61G
Description protein phosphatase 2 regulatory subunit B'gamma
Transcript NM_001161725   
Other Transcripts NM_001161726 , NM_002719 , NM_178586 , NM_178587   
Expression
Putative miRNA Targets on PPP2R5C
3'UTR of PPP2R5C
(miRNA target sites are highlighted)		 
>PPP2R5C|NM_001161725|3'UTR
   1 CCTCCGGGGCGCCGCGTCGGGGCCGGGCCCGCCAGTTCTTTTCCGGATTCTGTAGAAAATACATACTTCCTGTGCCATAC
  81 CAATCAGTTACACTCAAAGCTTTCTTGGACCCCGTTCCGTAGGCAATAACGTGCGTCCGCCTCAGCGCGAGATTAGGAGT
 161 TCAAACAATGGTGACTTCCCAGAGCCCGCTGGCAGAGCCGCGGGTTGACGACGGTGTCCTCGCAGTGTCGCCGCCACCCC
 241 AGCGTAGTCCAAGTCAGACTATTTCACAAAGTCAGAGCGATAGGAAAGCACCCTGCCCTTCATCTTCATGTTCTCCCAAA
 321 TGGAACTTAGGATCTTTTAACATAGGTGGTTCTGTGATAACATCAGTGTTTTCCAAATCAAAGGAACGCTTTAAAAAATA
 401 GGACCTATTTTTTAAGACTTTACAGCCTTTGAAATGGTTTCCACGTGATTGTTACGCCAGCAGTTCTCGTTTTGTTTGTT
 481 TTTCAATCTCAGTGAAATGGCTCTTTGCTTTCGAGTTCTCACGCAACGTACTGGGCAAATGACAATCCTCAGCCGCTGGT
 561 ATTTTCTAAGGGGTCTCTTCACTTTGATGAGTGACATGAACACCGTGTCTCCTTCTCTTGTGTGTACCTAAAGCCATATT
 641 TCCAAGTCTGTGGTACTCCAGGATTCCAGGAGTAAGCCTGTAGAAGAGATTTATTTTAAAAGAGATTGCTCTGAAATTTA
 721 TCTTAAAAGAGCTTGCTCTGTCTACCTTGACAGAAATTGGAGTTTTAAAATTATGTGTTAATATTTTTATTTGCAGATTT
 801 CGTTTCCGTCAACTTAAACATTGTTGCCCTTCAACAAGGCTCTTGAATTAATAAAATTATAGTCTCTAAGAATTCCACAT
 881 TTTATGGAAAGTTAGAGCAAAATCATTTTGAGTTAAGCCAGTTCTTAGCCTAATGCAAACTGCAGCGCCTTTAAGCATAA
 961 AGTAACACAACAGCATTGCACGGGGCCGGCACTGCCGCTGCCTTCACTGAAGGCTGCAGTGCTGTTCTGAGAGCTTGGAG
1041 GAGGCACCAGCGAGGATGACGTTTAGTGGAGCTCTTTCTGTTGAAAAGAGCTCACGTTATCAACACCTTGTAAGGAAAAT
1121 ACAGTGTCTGAGTTTTCATCGGTCTTCACATGCTGCTATATATTCCACAGAGTTCCTTGCATGTACTGAGCTTTTGTTTT
1201 AGATGGAATAGCACAAGGAGAAAAATCTTTAAACTTAGTGCTTTGTCTATTCTTTATTTCTCTCAGGGTGGCCAGTATTT
1281 TGACTTATTTATCCTGCTTGAAAGCTACTTGAGATGTGTACTGCTATTCTAAACACGTGATCTAGTTTCTTTCATCTCTG
1361 GCATAAGATTATATAACTTAATGTTAAGTGTCTTGAGGCATAAAAGACAAAATGTGGCTTATTTTAGGATCTGTTTTTTC
1441 ATCGAGGTCTCGGGTATCCTTTCAAAGATAGTGAGAAGCAGACACTGCTCCTTGTGCAGCTCTGGTACCTCCTGCCCACT
1521 GCTGTCACTTCAAGCCACTGGCAATGCTTCTGTCCTCGTGTCTTGGAGGAAAATCACCTGGGGGGAGGGGACTTCTTGTG
1601 GTAAGAGCAAGTGCAGGTATGAAATGCGAAGATTGCCCCAGCTAAAAGTGGACAAGTCCGCTTTGTGAGATGAATACTTC
1681 CTGAGAAACTTGACAAGTATCTCTCCATTTTACCATTATGAAAACTATCATTAAAAAAAACAGTTTAGATGCCTTCTCCT
1761 TTTGAGGGAAAAAGGGTGCTTTTTATTGTATAAAGCAGCGTCTTATGTATTTTGATATACCATTGTTTGAACTTCCGTCT
1841 TTAGCTGATAGATTCTCAAATATCCTTGATTTTGGATGTTCAGTATGTTTGTGAGAGAGGTTTCTGGGAAGACTCTCTTT
1921 TTGCCCTCGGGAAAAAGCAAAATATCAATGTTTGGGTGACTGTGTAAAGCTCAGTGTGTAAGAACATCTTTTTGTCTAGG
2001 TTTTCTTTCTGCTCTTTATTGAAGACAAACACTCACCAAAAAGAAAAATAAAAGTTTTCAGAGAAACTAATTTTCTTTGG
2081 CAAGAGTATTACTTAATATTTTGGCCTCCTAAAGTTTCCCTAGTTAGTACTCGGACTCCTGTGCTAATTGTCAGCTTACA
2161 TATCATTGTATAGAGACTGTTTATTCTGTACCAAACTGATTTCAAAAGTACTACATTGAAAATAAACCGGTGACTGTTTT
2241 TCTTCATAAAGTTCTGCGTTTGGCATCTTCACTCTTTCCAAAATGTATCTGTACATCAGAAATGTCACTATTCCAAGTGT
2321 CTTTTTAGTGTGGCTTTAGTATGGCTTCCTTTTAATATTGTACATACATTGTATCTTTGTTTTATGGTAATAAGTAATAA
2401 AAATGTAGACTTCATATTTTGTACAAAATGTCCTATGTACAGAATAAAAAAGTTCATAGAAACAGCAAATATAGGTAAGT
2481 GGCACAATTATTTTTCTTTAGAAAATATCTGTAACTTTATGCATTAGTGAAATGTTAAGTACCGACATATTTTTTAACAT
2561 TTTGTAATTCAAAACTTTTTGTTTTGACATTGTTTATGAAGAGAAACTTCATACACTTGCCATTTAATATGCTCTTTTAT
2641 CTAATTTTCAAAAACTCTAAAAAACGGTGTATCATATGGACTAAATAAAGAACATGTGAATTTTATTGCTCATCATGAAA
2721 AAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aaaGAGGAGGGUAGAAGGUGUg 5'
             || ||  :|| ||||||| 
Target 5' atgCTGCT-ATATATTCCACAg 3'
 1150 - 1170 154.00 -14.50
2 
miRNA  3' aaagaGGAGGGU-AGAAGGUGUg 5'
               :|||: |   ||||||| 
Target 5' tatagTCTCTAAGAATTCCACAt 3'
 858 - 880 145.00 -14.70
3 
miRNA  3' aaagAGG---AGGGU-AGAAGGUGUg 5'
              |||   ||  | | ||:|||| 
Target 5' gtagTCCAAGTCAGACTATTTCACAa 3'
 244 - 269 130.00 -9.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26990188 12 COSMIC
COSN26990187 16 COSMIC
COSN30192100 25 COSMIC
COSN30520920 30 COSMIC
COSN28885971 46 COSMIC
COSN30505620 76 COSMIC
COSN30503849 80 COSMIC
COSN30152587 96 COSMIC
COSN26562113 134 COSMIC
COSN31593198 148 COSMIC
COSN31490334 150 COSMIC
COSN1164381 162 COSMIC
COSN23068174 163 COSMIC
COSN31533138 216 COSMIC
COSN31485165 332 COSMIC
COSN24642850 360 COSMIC
COSN23816021 365 COSMIC
COSN26423903 451 COSMIC
COSN31564898 513 COSMIC
COSN31544539 564 COSMIC
COSN31486433 590 COSMIC
COSN30175907 599 COSMIC
COSN31597012 605 COSMIC
COSN29557133 668 COSMIC
COSN5380667 988 COSMIC
COSN31490804 1030 COSMIC
COSN8821949 1035 COSMIC
COSN26599367 1115 COSMIC
COSN26603577 1218 COSMIC
COSN31547272 1261 COSMIC
COSN15773655 1429 COSMIC
COSN32056630 1741 COSMIC
COSN16497806 1806 COSMIC
COSN29478306 1923 COSMIC
COSN29478858 1924 COSMIC
COSN25889932 1951 COSMIC
COSN21231701 1994 COSMIC
COSN28815888 2040 COSMIC
COSN31486442 2131 COSMIC
COSN31548020 2192 COSMIC
COSN31549306 2204 COSMIC
COSN20156440 2247 COSMIC
COSN31578533 2436 COSMIC
COSN31536136 2454 COSMIC
COSN28758657 2573 COSMIC
COSN22366323 2635 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1399310562 3 dbSNP
rs1431642035 4 dbSNP
rs750847624 8 dbSNP
rs756578334 9 dbSNP
rs1278822517 11 dbSNP
rs1327945731 17 dbSNP
rs372065291 20 dbSNP
rs1277151962 23 dbSNP
rs754321822 24 dbSNP
rs754466626 25 dbSNP
rs778287363 26 dbSNP
rs1334085442 27 dbSNP
rs1253436242 28 dbSNP
rs1481253826 28 dbSNP
rs747743962 30 dbSNP
rs1267346665 31 dbSNP
rs1484922591 32 dbSNP
rs1204835627 33 dbSNP
rs776562796 35 dbSNP
rs777704707 36 dbSNP
rs1223775106 37 dbSNP
rs746838961 39 dbSNP
rs770752812 42 dbSNP
rs1346799400 44 dbSNP
rs776584253 45 dbSNP
rs111800390 46 dbSNP
rs973639005 47 dbSNP
rs745823197 50 dbSNP
rs1450974942 51 dbSNP
rs768716123 53 dbSNP
rs1397192277 55 dbSNP
rs992335469 57 dbSNP
rs1324216231 65 dbSNP
rs917979207 70 dbSNP
rs1222630759 73 dbSNP
rs1464392608 89 dbSNP
rs1361994930 91 dbSNP
rs1428830874 92 dbSNP
rs948181815 93 dbSNP
rs931979732 97 dbSNP
rs1409776818 98 dbSNP
rs987965931 100 dbSNP
rs1420204157 106 dbSNP
rs1253337962 107 dbSNP
rs1199075612 109 dbSNP
rs1461113702 113 dbSNP
rs911949266 114 dbSNP
rs1203833706 115 dbSNP
rs111530226 119 dbSNP
rs935408360 122 dbSNP
rs1277248482 126 dbSNP
rs555865162 127 dbSNP
rs139746163 131 dbSNP
rs1484914314 136 dbSNP
rs947317933 150 dbSNP
rs538110830 153 dbSNP
rs1471071042 158 dbSNP
rs750026655 161 dbSNP
rs1158039716 164 dbSNP
rs892377684 167 dbSNP
rs1480416856 178 dbSNP
rs1174652193 179 dbSNP
rs879109096 186 dbSNP
rs1470583918 187 dbSNP
rs1414674498 189 dbSNP
rs933186611 191 dbSNP
rs1186001070 197 dbSNP
rs1444564570 201 dbSNP
rs1244064006 202 dbSNP
rs1051531481 204 dbSNP
rs780846569 213 dbSNP
rs888885758 214 dbSNP
rs1007282503 219 dbSNP
rs758049485 223 dbSNP
rs1016352127 231 dbSNP
rs1064430 234 dbSNP
rs898793099 235 dbSNP
rs1005021134 249 dbSNP
rs1382017887 249 dbSNP
rs765989510 254 dbSNP
rs1294804343 255 dbSNP
rs1454415880 256 dbSNP
rs1345995944 262 dbSNP
rs555254604 269 dbSNP
rs973670136 270 dbSNP
rs1029211300 272 dbSNP
rs1025936021 280 dbSNP
rs951595540 288 dbSNP
rs1387141365 293 dbSNP
rs1161545968 296 dbSNP
rs1424565193 299 dbSNP
rs1330941473 302 dbSNP
rs953512576 303 dbSNP
rs992350235 308 dbSNP
rs1283796048 309 dbSNP
rs1025122740 319 dbSNP
rs375185688 321 dbSNP
rs1447235211 322 dbSNP
rs1263205072 323 dbSNP
rs564502107 331 dbSNP
rs1223819405 341 dbSNP
rs969889490 343 dbSNP
rs980844189 344 dbSNP
rs1358607158 353 dbSNP
rs925276005 362 dbSNP
rs867934823 363 dbSNP
rs1337161370 366 dbSNP
rs1269385954 369 dbSNP
rs1431677971 375 dbSNP
rs1301362727 378 dbSNP
rs936722874 387 dbSNP
rs1404450377 388 dbSNP
rs116067941 389 dbSNP
rs1165967813 390 dbSNP
rs1254680444 392 dbSNP
rs1428415239 398 dbSNP
rs1419169403 403 dbSNP
rs1168913467 408 dbSNP
rs913084649 414 dbSNP
rs947182174 422 dbSNP
rs1269020517 424 dbSNP
rs1224548572 427 dbSNP
rs1436017888 428 dbSNP
rs1272003249 431 dbSNP
rs913847404 442 dbSNP
rs1215010370 449 dbSNP
rs377515379 450 dbSNP
rs11553289 452 dbSNP
rs1056823698 454 dbSNP
rs1398599898 456 dbSNP
rs888922280 457 dbSNP
rs1440631260 462 dbSNP
rs943116386 469 dbSNP
rs1329929362 470 dbSNP
rs1412046656 471 dbSNP
rs1404395044 478 dbSNP
rs531371699 479 dbSNP
rs1037496338 487 dbSNP
rs1479911010 492 dbSNP
rs533768016 502 dbSNP
rs1166214539 504 dbSNP
rs898902424 509 dbSNP
rs547895549 510 dbSNP
rs533134686 512 dbSNP
rs1204926220 513 dbSNP
rs1741143 514 dbSNP
rs1301180136 517 dbSNP
rs1014659526 524 dbSNP
rs1025967090 526 dbSNP
rs1324551602 527 dbSNP
rs568180613 527 dbSNP
rs887373998 528 dbSNP
rs1222177896 531 dbSNP
rs781743700 532 dbSNP
rs576997097 533 dbSNP
rs1445033720 536 dbSNP
rs1404287090 544 dbSNP
rs1336505416 547 dbSNP
rs527379161 554 dbSNP
rs969543410 556 dbSNP
rs1406443249 560 dbSNP
rs1177563622 561 dbSNP
rs1398497119 564 dbSNP
rs547120950 573 dbSNP
rs878885523 578 dbSNP
rs3134676 582 dbSNP
rs1182829310 586 dbSNP
rs1461919383 589 dbSNP
rs1265288496 590 dbSNP
rs1358816564 595 dbSNP
rs1220405670 597 dbSNP
rs1277370169 598 dbSNP
rs1381301625 612 dbSNP
rs958347248 612 dbSNP
rs1314785733 616 dbSNP
rs1018957929 619 dbSNP
rs1383037665 620 dbSNP
rs1304168451 621 dbSNP
rs1204183154 623 dbSNP
rs956895302 629 dbSNP
rs988186505 637 dbSNP
rs1231542157 644 dbSNP
rs988122624 651 dbSNP
rs1162673510 655 dbSNP
rs1444967950 658 dbSNP
rs915290618 659 dbSNP
rs1184936964 660 dbSNP
rs913877104 666 dbSNP
rs1485675360 680 dbSNP
rs968096039 683 dbSNP
rs570415736 685 dbSNP
rs1333645751 686 dbSNP
rs1291749287 696 dbSNP
rs1401074089 708 dbSNP
rs1361985460 709 dbSNP
rs1293885355 711 dbSNP
rs188031658 726 dbSNP
rs778306865 727 dbSNP
rs749651936 729 dbSNP
rs1385518973 737 dbSNP
rs1443454551 739 dbSNP
rs550468085 747 dbSNP
rs1372283023 748 dbSNP
rs1363194463 757 dbSNP
rs570280459 758 dbSNP
rs1302428188 773 dbSNP
rs1425231812 797 dbSNP
rs1369924475 798 dbSNP
rs910458885 808 dbSNP
rs943251760 811 dbSNP
rs536018360 813 dbSNP
rs1327878171 816 dbSNP
rs937303279 817 dbSNP
rs1352534139 821 dbSNP
rs10131687 823 dbSNP
rs1315960723 824 dbSNP
rs929016003 826 dbSNP
rs192572996 828 dbSNP
rs940300507 835 dbSNP
rs1489761178 838 dbSNP
rs565710908 838 dbSNP
rs1299956052 840 dbSNP
rs1227241583 842 dbSNP
rs1340604551 858 dbSNP
rs1214481508 859 dbSNP
rs74693721 860 dbSNP
rs1306538377 862 dbSNP
rs1036123090 898 dbSNP
rs535108872 908 dbSNP
rs1204765663 912 dbSNP
rs1343022793 916 dbSNP
rs898951053 930 dbSNP
rs745898990 935 dbSNP
rs895448042 943 dbSNP
rs1405473119 944 dbSNP
rs1296203890 953 dbSNP
rs994588643 953 dbSNP
rs1050641788 957 dbSNP
rs1354915115 963 dbSNP
rs889252073 972 dbSNP
rs1243317500 979 dbSNP
rs1460618649 980 dbSNP
rs1013847074 983 dbSNP
rs1009168436 987 dbSNP
rs557897684 987 dbSNP
rs956712056 989 dbSNP
rs1249097386 992 dbSNP
rs1374313729 997 dbSNP
rs1481142472 1008 dbSNP
rs1475490798 1025 dbSNP
rs1260403885 1036 dbSNP
rs1200079082 1048 dbSNP
rs1321047537 1054 dbSNP
rs1167260464 1062 dbSNP
rs1233394711 1075 dbSNP
rs1417346600 1085 dbSNP
rs1009557117 1087 dbSNP
rs1470822054 1092 dbSNP
rs1373700435 1094 dbSNP
rs541715799 1097 dbSNP
rs1468417909 1102 dbSNP
rs1405712460 1107 dbSNP
rs1177204808 1111 dbSNP
rs1467605726 1113 dbSNP
rs905433883 1128 dbSNP
rs1405573140 1141 dbSNP
rs968126896 1143 dbSNP
rs1002402851 1145 dbSNP
rs1420220969 1149 dbSNP
rs1032903189 1151 dbSNP
rs577944698 1157 dbSNP
rs927162855 1157 dbSNP
rs958164208 1159 dbSNP
rs1459678857 1166 dbSNP
rs1200694753 1175 dbSNP
rs1262168285 1175 dbSNP
rs958761466 1183 dbSNP
rs772143870 1184 dbSNP
rs1327095236 1188 dbSNP
rs1430151952 1192 dbSNP
rs1238168457 1202 dbSNP
rs1354394342 1204 dbSNP
rs1311178558 1205 dbSNP
rs1020914929 1207 dbSNP
rs545798610 1209 dbSNP
rs1381798862 1210 dbSNP
rs954749194 1218 dbSNP
rs562407010 1219 dbSNP
rs987426083 1228 dbSNP
rs1337591785 1242 dbSNP
rs910499338 1250 dbSNP
rs1224457629 1252 dbSNP
rs1382810224 1253 dbSNP
rs1262910012 1259 dbSNP
rs746944018 1267 dbSNP
rs1158129366 1268 dbSNP
rs1322329683 1290 dbSNP
rs1201376269 1297 dbSNP
rs964968326 1299 dbSNP
rs11553290 1303 dbSNP
rs973278217 1305 dbSNP
rs920393280 1306 dbSNP
rs575837516 1309 dbSNP
rs1382747378 1314 dbSNP
rs1036070863 1336 dbSNP
rs45458393 1337 dbSNP
rs1244161808 1338 dbSNP
rs1447049823 1341 dbSNP
rs755967624 1346 dbSNP
rs930390719 1357 dbSNP
rs1259038687 1359 dbSNP
rs561538377 1364 dbSNP
rs772624641 1378 dbSNP
rs1481395575 1381 dbSNP
rs1176804332 1384 dbSNP
rs1488558378 1386 dbSNP
rs1288137009 1398 dbSNP
rs1243724435 1399 dbSNP
rs149329037 1409 dbSNP
rs768605500 1409 dbSNP
rs889291936 1413 dbSNP
rs761759610 1419 dbSNP
rs1247246021 1420 dbSNP
rs769770723 1426 dbSNP
rs773030686 1429 dbSNP
rs1009444741 1430 dbSNP
rs1468096946 1434 dbSNP
rs949731252 1439 dbSNP
rs1040538822 1447 dbSNP
rs1044437643 1451 dbSNP
rs1362558788 1452 dbSNP
rs905464398 1453 dbSNP
rs1009756658 1470 dbSNP
rs527432556 1470 dbSNP
rs1386188094 1472 dbSNP
rs1022281607 1474 dbSNP
rs1741144 1476 dbSNP
rs563948198 1479 dbSNP
rs1371023548 1480 dbSNP
rs1191817421 1486 dbSNP
rs1381667137 1489 dbSNP
rs56028013 1491 dbSNP
rs1220087511 1495 dbSNP
rs1034142204 1500 dbSNP
rs962593707 1508 dbSNP
rs1211461905 1511 dbSNP
rs1058327 1512 dbSNP
rs993105972 1529 dbSNP
rs1283277832 1530 dbSNP
rs1021030723 1536 dbSNP
rs1342371268 1540 dbSNP
rs1281468889 1542 dbSNP
rs1344024150 1559 dbSNP
rs1325908057 1561 dbSNP
rs570314800 1585 dbSNP
rs890528002 1586 dbSNP
rs1396257116 1591 dbSNP
rs1024143912 1596 dbSNP
rs1425131334 1599 dbSNP
rs759023299 1602 dbSNP
rs536151918 1603 dbSNP
rs1480050317 1605 dbSNP
rs971964081 1606 dbSNP
rs1200937123 1610 dbSNP
rs1435820994 1620 dbSNP
rs1194745690 1629 dbSNP
rs1008877036 1634 dbSNP
rs187887022 1638 dbSNP
rs549637931 1646 dbSNP
rs920273959 1655 dbSNP
rs1017998726 1657 dbSNP
rs1350975919 1660 dbSNP
rs930254827 1661 dbSNP
rs1281533098 1675 dbSNP
rs1490713839 1686 dbSNP
rs1200056034 1694 dbSNP
rs1268141986 1695 dbSNP
rs1440654088 1695 dbSNP
rs773167102 1699 dbSNP
rs139573269 1700 dbSNP
rs1402069090 1706 dbSNP
rs1173601509 1712 dbSNP
rs534832524 1717 dbSNP
rs377459318 1719 dbSNP
rs1413355347 1726 dbSNP
rs558202306 1729 dbSNP
rs1192787018 1730 dbSNP
rs1232081748 1733 dbSNP
rs910325453 1733 dbSNP
rs944468598 1734 dbSNP
rs1459235393 1735 dbSNP
rs1241587313 1736 dbSNP
rs1040965827 1740 dbSNP
rs1203300322 1743 dbSNP
rs1367520018 1744 dbSNP
rs892628180 1749 dbSNP
rs1280842998 1751 dbSNP
rs1222550170 1754 dbSNP
rs1425460061 1756 dbSNP
rs973693003 1760 dbSNP
rs571564684 1767 dbSNP
rs1449526036 1769 dbSNP
rs1027490401 1795 dbSNP
rs950568331 1799 dbSNP
rs1303045968 1800 dbSNP
rs532443759 1801 dbSNP
rs537006672 1813 dbSNP
rs1359182278 1815 dbSNP
rs1393451951 1818 dbSNP
rs1177683819 1819 dbSNP
rs1043916584 1823 dbSNP
rs1308202525 1833 dbSNP
rs1335912464 1835 dbSNP
rs149679553 1837 dbSNP
rs917029901 1838 dbSNP
rs1383188227 1840 dbSNP
rs918398893 1850 dbSNP
rs1181441517 1853 dbSNP
rs552257584 1860 dbSNP
rs1360938212 1862 dbSNP
rs1287303132 1868 dbSNP
rs541708124 1877 dbSNP
rs896584647 1882 dbSNP
rs979807944 1891 dbSNP
rs1357650815 1892 dbSNP
rs1222647600 1906 dbSNP
rs537773530 1913 dbSNP
rs1314815911 1916 dbSNP
rs926919917 1922 dbSNP
rs1227374643 1929 dbSNP
rs938280499 1932 dbSNP
rs1379532010 1933 dbSNP
rs1304050717 1937 dbSNP
rs1489847483 1939 dbSNP
rs753210282 1949 dbSNP
rs192566952 1953 dbSNP
rs1298691200 1954 dbSNP
rs1421447921 1961 dbSNP
rs1013667123 1969 dbSNP
rs1163892570 1971 dbSNP
rs1197256686 1973 dbSNP
rs1250985705 1992 dbSNP
rs1418347612 1993 dbSNP
rs2623 1999 dbSNP
rs894053773 2002 dbSNP
rs569314020 2012 dbSNP
rs772900798 2013 dbSNP
rs1042515767 2019 dbSNP
rs1477512286 2030 dbSNP
rs1387362215 2032 dbSNP
rs961837415 2033 dbSNP
rs890558955 2039 dbSNP
rs971995167 2060 dbSNP
rs1009368117 2070 dbSNP
rs1291503570 2071 dbSNP
rs1027545578 2076 dbSNP
rs1017611062 2084 dbSNP
rs1314373990 2091 dbSNP
rs1212474835 2093 dbSNP
rs531924786 2097 dbSNP
rs1364212217 2110 dbSNP
rs778488403 2110 dbSNP
rs1463983044 2127 dbSNP
rs1363680539 2128 dbSNP
rs951984932 2134 dbSNP
rs900461573 2135 dbSNP
rs540784803 2144 dbSNP
rs1396217628 2148 dbSNP
rs910217954 2151 dbSNP
rs994843562 2159 dbSNP
rs1328842052 2162 dbSNP
rs1384571638 2168 dbSNP
rs1424415550 2168 dbSNP
rs1479726857 2169 dbSNP
rs1267329848 2174 dbSNP
rs1192310113 2184 dbSNP
rs1246017549 2192 dbSNP
rs1489649270 2193 dbSNP
rs77411489 2209 dbSNP
rs757571056 2212 dbSNP
rs1319790606 2213 dbSNP
rs1229498064 2225 dbSNP
rs1219987903 2226 dbSNP
rs1251889988 2229 dbSNP
rs1300451920 2230 dbSNP
rs766534501 2235 dbSNP
rs1387280663 2243 dbSNP
rs1369385343 2246 dbSNP
rs983305463 2252 dbSNP
rs866960806 2255 dbSNP
rs914074906 2258 dbSNP
rs779123958 2259 dbSNP
rs1024117784 2266 dbSNP
rs1193910836 2286 dbSNP
rs1401357126 2288 dbSNP
rs1172885777 2289 dbSNP
rs1468254869 2298 dbSNP
rs1043968357 2303 dbSNP
rs1802865 2310 dbSNP
rs971147157 2311 dbSNP
rs35946432 2313 dbSNP
rs980221470 2329 dbSNP
rs1435439837 2331 dbSNP
rs1248854871 2340 dbSNP
rs927062488 2344 dbSNP
rs1245149120 2345 dbSNP
rs1457021884 2362 dbSNP
rs1238355431 2365 dbSNP
rs1461963035 2372 dbSNP
rs532793814 2385 dbSNP
rs1200172537 2391 dbSNP
rs1342174496 2417 dbSNP
rs904141814 2421 dbSNP
rs1182993210 2422 dbSNP
rs1313951584 2423 dbSNP
rs1304566190 2429 dbSNP
rs1383476880 2431 dbSNP
rs935701124 2439 dbSNP
rs1430437654 2447 dbSNP
rs989820753 2448 dbSNP
rs1450732130 2453 dbSNP
rs543488879 2461 dbSNP
rs1401514724 2473 dbSNP
rs915518135 2488 dbSNP
rs1468000108 2498 dbSNP
rs1373057922 2500 dbSNP
rs1158595540 2508 dbSNP
rs938257401 2510 dbSNP
rs1382555442 2512 dbSNP
rs1055572923 2519 dbSNP
rs1407753311 2524 dbSNP
rs945608593 2533 dbSNP
rs145522788 2544 dbSNP
rs1014091961 2545 dbSNP
rs776795896 2547 dbSNP
rs372550610 2549 dbSNP
rs1283740202 2550 dbSNP
rs1491070146 2550 dbSNP
rs1354069284 2560 dbSNP
rs897677317 2565 dbSNP
rs34469985 2571 dbSNP
rs993360592 2589 dbSNP
rs765909810 2602 dbSNP
rs1027471954 2612 dbSNP
rs1306874285 2613 dbSNP
rs1397807783 2615 dbSNP
rs890590018 2616 dbSNP
rs1298050547 2622 dbSNP
rs1173010182 2625 dbSNP
rs1264776739 2628 dbSNP
rs746107042 2633 dbSNP
rs772088967 2642 dbSNP
rs1471590183 2656 dbSNP
rs1203258127 2657 dbSNP
rs1007469008 2659 dbSNP
rs944810797 2660 dbSNP
rs1017696646 2661 dbSNP
rs1425004050 2662 dbSNP
rs1260415757 2663 dbSNP
rs965701495 2666 dbSNP
rs185058668 2667 dbSNP
rs549674234 2674 dbSNP
rs1261592928 2677 dbSNP
rs975821484 2685 dbSNP
rs780083453 2690 dbSNP
rs147411271 2694 dbSNP
rs1430405205 2695 dbSNP
rs1469668215 2699 dbSNP
rs1247264081 2705 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aaagAGGAGGGUA-GAAGGUGUg 5'
              ||:|| ||| || |:|:| 
Target 5' ----UCUUCACAUGCUGCUAUAu 3'
 		1 - 19
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 5527.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aaaGAGGAGGGUAGAAGGUGUg 5'
             || ||  :|| ||||||| 
Target 5' augCUGCU-AUAUAUUCCACAg 3'
 		9 - 29
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000422945.2 | 3UTR | UCUUCACAUGCUGCUAUAUAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000422945.2 | 3UTR | GUCUUCACAUGCUGCUAUAUAUUCCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
85 hsa-miR-6833-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055111 SCD stearoyl-CoA desaturase 2 2
MIRT056784 ARID5B AT-rich interaction domain 5B 2 2
MIRT063833 SRP9 signal recognition particle 9 2 6
MIRT068906 TPRG1L tumor protein p63 regulated 1 like 2 2
MIRT087861 CBY1 chibby family member 1, beta catenin antagonist 2 4
MIRT102313 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT189645 AKAP11 A-kinase anchoring protein 11 2 2
MIRT191247 STYX serine/threonine/tyrosine interacting protein 2 2
MIRT195912 SRSF11 serine and arginine rich splicing factor 11 2 4
MIRT215291 CREBRF CREB3 regulatory factor 2 2
MIRT219058 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT240350 UBXN2B UBX domain protein 2B 2 2
MIRT244626 PLAG1 PLAG1 zinc finger 2 2
MIRT271181 PTPN14 protein tyrosine phosphatase, non-receptor type 14 2 2
MIRT277519 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 4
MIRT284544 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT286223 TMEM97 transmembrane protein 97 2 4
MIRT314185 OCLN occludin 2 4
MIRT336247 SKI SKI proto-oncogene 2 4
MIRT357689 PAIP2 poly(A) binding protein interacting protein 2 2 2
MIRT447422 MED21 mediator complex subunit 21 2 2
MIRT451274 ZNF101 zinc finger protein 101 2 2
MIRT453571 CRCP CGRP receptor component 2 2
MIRT454361 ASAH2 N-acylsphingosine amidohydrolase 2 2 2
MIRT460906 POLQ DNA polymerase theta 2 2
MIRT469362 REST RE1 silencing transcription factor 2 6
MIRT470269 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 2 2
MIRT471927 NRAS NRAS proto-oncogene, GTPase 2 2
MIRT474227 LCLAT1 lysocardiolipin acyltransferase 1 2 2
MIRT480241 C8orf58 chromosome 8 open reading frame 58 2 2
MIRT480543 BZW1 basic leucine zipper and W2 domains 1 2 2
MIRT480924 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT497343 RPP25L ribonuclease P/MRP subunit p25 like 2 2
MIRT498824 DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 2 8
MIRT498928 TMEM106B transmembrane protein 106B 2 8
MIRT499584 INTU inturned planar cell polarity protein 2 4
MIRT500118 ZNF106 zinc finger protein 106 2 4
MIRT500474 ZC3H11A zinc finger CCCH-type containing 11A 2 2
MIRT501717 OVOL1 ovo like transcriptional repressor 1 2 2
MIRT501908 MBD4 methyl-CpG binding domain 4, DNA glycosylase 2 4
MIRT502197 HSPB8 heat shock protein family B (small) member 8 2 2
MIRT505229 UBE2D3 ubiquitin conjugating enzyme E2 D3 2 2
MIRT505945 RAN RAN, member RAS oncogene family 2 6
MIRT507971 BCL2L13 BCL2 like 13 2 4
MIRT512251 ARPP19 cAMP regulated phosphoprotein 19 2 6
MIRT513024 GPT2 glutamic--pyruvic transaminase 2 2 2
MIRT530791 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT533403 TXLNG taxilin gamma 2 2
MIRT546728 RNF217 ring finger protein 217 2 2
MIRT554087 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 2
MIRT559924 SOD2 superoxide dismutase 2 2 2
MIRT560258 TMEM236 transmembrane protein 236 2 2
MIRT560412 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT560420 ANGPTL3 angiopoietin like 3 2 2
MIRT560495 KCNJ10 potassium voltage-gated channel subfamily J member 10 2 2
MIRT560549 SIGLEC14 sialic acid binding Ig like lectin 14 2 2
MIRT560802 PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2 2
MIRT560883 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT560997 C8orf37 chromosome 8 open reading frame 37 2 2
MIRT561090 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT561193 LDHD lactate dehydrogenase D 2 2
MIRT561835 NREP neuronal regeneration related protein 2 2
MIRT562393 EIF4E eukaryotic translation initiation factor 4E 2 2
MIRT568153 CCDC6 coiled-coil domain containing 6 2 2
MIRT572725 NUP188 nucleoporin 188 2 2
MIRT572886 ADCY2 adenylate cyclase 2 2 2
MIRT575747 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b 2 2
MIRT606770 KIAA0040 KIAA0040 2 5
MIRT620360 CD55 CD55 molecule (Cromer blood group) 2 2
MIRT623579 IREB2 iron responsive element binding protein 2 2 2
MIRT640726 PHF13 PHD finger protein 13 2 2
MIRT651579 WDR26 WD repeat domain 26 2 2
MIRT674927 C1orf116 chromosome 1 open reading frame 116 2 2
MIRT687378 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT687699 KRR1 KRR1, small subunit processome component homolog 2 2
MIRT693331 E2F2 E2F transcription factor 2 2 2
MIRT695289 TK1 thymidine kinase 1 2 2
MIRT697691 WAC WW domain containing adaptor with coiled-coil 2 2
MIRT699810 SDHD succinate dehydrogenase complex subunit D 2 2
MIRT702280 LEPROT leptin receptor overlapping transcript 2 2
MIRT708498 FAM9C family with sequence similarity 9 member C 2 2
MIRT710101 HEY2 hes related family bHLH transcription factor with YRPW motif 2 2 2
MIRT717883 GBP4 guanylate binding protein 4 2 2
MIRT719248 MS4A1 membrane spanning 4-domains A1 2 2
MIRT719958 SAMD15 sterile alpha motif domain containing 15 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6833 Cisplatin 5460033 NSC119875 approved sensitive cell line (CIS)
hsa-miR-6833-5p Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-6833-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (BAS)
hsa-miR-6833-5p Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-6833-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)

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