miRTarBase - #MIRT282672


—
pre-miRNA Information
pre-miRNA hsa-mir-3678   
Genomic Coordinates chr17: 75406069 - 75406162
Description Homo sapiens miR-3678 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3678-3p
Sequence 69| CUGCAGAGUUUGUACGGACCGG |90
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs988363493 1 dbSNP
rs753118178 5 dbSNP
rs1424776090 14 dbSNP
rs1475188526 15 dbSNP
rs1163369708 17 dbSNP
rs1174219930 19 dbSNP
rs915488824 20 dbSNP
rs1273558782 21 dbSNP
rs755095016 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SYNM   
Synonyms DMN, SYN
Description synemin
Transcript NM_015286   
Other Transcripts NM_145728   
Expression
Putative miRNA Targets on SYNM
3'UTR of SYNM
(miRNA target sites are highlighted)		 
>SYNM|NM_015286|3'UTR
   1 TAAGCAGAAACATTTTGTTTTAATGGCAGCCTGTTGGCGACGTGCCAACATCCAAAGGCCTTAACTTATTTTAAGAGGCC
  81 GAGGGAGTCTATGAAAATCTCCCCTTTTTTACTTTTTTAAAGAGTACTCCCGGCATGGTCAATTTCCTTTATAGTTAATC
 161 CGTAAAGGTTTCCAGTTAATTCATGCCTTAAAAGGCACTGCAATTTTATTTTTGAGTTGGGACTTTTACAAAACACTTTT
 241 TTCCCTGGAGTCTTCTCTCCACTTCTGGAGATGAATTTCTATGTTTTGCACCTGGTCACAGACATGGCTTGCATCTGTTT
 321 GAAACTACAATTAATTATAGATGTCAAAACATTAACCAGATTAAAGTAATATATTTAAGAGTAAATTTTGCTTGCATGTG
 401 CTAATATGAAATAACAGACTAACATTTTAGGGGAAAAATAAATACAATTTAGACTCTAAAAAGTCTTTTCAAAAAGAAAT
 481 GGGAAATAGGCAGACTGTTTATGTTAAAAAAATTCTTGCTAAATGATTTCATCTTTAGGAAAAAATTACTTGCCATATAG
 561 AGCTAAATTCATCTTAAGACTTGAATGAATTGCTTTCTATGTACAGAACTTTAAACAATATAGTATTTATGGCGAGGACA
 641 GCTGTAGTCTGTTGTGATATTTCACATTCTATTTGCACAGGTTCCCTGGCACTGGTAGGGTAGATGATTATTGGGAATCG
 721 CTTACAGTACCATTTCATTTTTTGGCACTAGGTCATTAAGTAGCACACAGTCTGAATGCCCTTTTCTGGAGTGGCCAGTT
 801 CCTATCAGACTGTGCAGACTTGCGCTTCTCTGCACCTTATCCCTTAGCACCCAAACATTTAATTTCACTGGTGGGAGGTA
 881 GACCTTGAAGACAATGAAGAGAATGCCGATACTCAGACTGCAGCTGGACCGGCAAGCTGGCTGTGTACAGGAAAATTGGA
 961 AGCACACAGTGGACTGTGCCTCTTAAAGATGCCTTTCCCAACCCTCCATTCATGGGATGCAGGTCTTTCTGAGCTCAAGG
1041 GTGAAAGATGAATACAATAACAACCATGAACCCACCTCACGGAAGCTTTTTTTGCACTTTGAACAGAAGTCATTGCAGTT
1121 GGGGTGTTTTGTCCAGGGAAACAGTTTATTAAATAGAAGGATGTTTTGGGGAAGGAACTGGATATCTCTCCTGCAGCCCA
1201 GCACCGAGATACCCAGGACGGGCCTGGGGGGCGAGAAAGGCCCCCATGCTCATGGGCCGCGGAGTGTGGACCTGTAGATA
1281 GGCACCACCGAGTTTAAGATACTGGGATGAGCATGCTTCATTGGATTCATTTTATTTTACACGTCAGTATTGTTTTAAAG
1361 TTTCTGTCTGTAAAGTGTAGCATCATATATAAAAAGAGTTTCGCTAGCAGCGCATTTTTTTTAGTTCAGGCTAGCTTCTT
1441 TCACATAATGCTGTCTCAGCTGTATTTCCAGTAACACAGCATCATCGCACTGACTGTGGCGCACTGGGGAATAACAGTCT
1521 GAGCTAGCACCACCCTCAGCCAGGCTACAACGACAGCACTGGAGGGTCTTCCCTCTCAGATTCACCTGGAGGCCCTCAGA
1601 CCCCCAGGGTGCACGTCTCCCCAGGTCCTGGGAGTGGCTACCGCAGGTAGTTTCTGGAGAGCACGTTTTCTTCATTGATA
1681 AGTGGAGGAGAAATGCAGCACAGCTTTCAAGATACTATTTTAAAAACACCATGAATCAGATAGGGAAAGAAAGTTGATTG
1761 GAATAGCAAGTTTAAACCTTTGTTGTCCATCTGCCAAATGAACTAGTGATTGTCAGACTGGTATGGAGGTGACTGCTTTG
1841 TAAGGTTTTGTCGTTTCTAATACAGACAGAGATGTGCTGATTTTGTTTTAGCTGTAACAGGTAATGGTTTTTGGATAGAT
1921 GATTGACTGGTGAGAATTTGGTCAAGGTGACAGCCTCCTGTCTGATGACAGGACAGACTGGTGGTGAGGAGTCTAAGTGG
2001 GCTCAGTTTGATGTCAGTGTCTGGGCTCATGACTTGTAAATGGAAGCTGATGTGAACAGGTAATTAATATTATGACCCAC
2081 TTCTATTTACTTTGGGAAATATCTTGGATCTTAATTATCATCTGCAAGTTTCAAGAAGTATTCTGCCAAAAGTATTTACA
2161 AGTATGGACTCATGAGCTATTGTTGGTTGCTAAATGTGAATCACGCGGGAGTGAGTGTGCCCTTCACACTGTGACATTGT
2241 GACATTGTGACAAGCTCCATGTCCTTTAAAATCAGTCACTCTGCACACAAGAGAAATCAACTTCGTGGTTGGATGGGGCC
2321 GGAACACAACCAGTCTTTTTGTATTTATTGTTACTGAGACAAAACAGTACTCACTGAGTGTTTTTCAGTTTCCTACTGGT
2401 GGTTTTGATATTGTTTGTTTAAGATGTATATTTAGAATGACATCATCTAAGAAGCTGATTTTGCTAAACTCCTGTTCCCT
2481 ACAATGGGAAATGTCACAAGAATGTGCAAAAATAAAAATCTGAGGAAAAAACCCACA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggcCAGG-CAUGUU------UGAGACGUc 5'
             ||||  || ||      |||||||| 
Target 5' catGTCCTTTAAAATCAGTCACTCTGCAc 3'
 2258 - 2286 153.00 -13.20
2 
miRNA  3' ggcCAGGCAUGUUU---------GAGACGUc 5'
             | |:||:||:|         ||||||| 
Target 5' tcaGACTGTGCAGACTTGCGCTTCTCTGCAc 3'
 805 - 835 151.00 -17.00
3 
miRNA  3' ggccaGGCAUGUU-UGAGACGUc 5'
               || || || :| ||||| 
Target 5' tcatgCCTTAAAAGGCACTGCAa 3'
 181 - 203 125.00 -8.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31571431 27 COSMIC
COSN511023 39 COSMIC
COSN20078210 40 COSMIC
COSN30514104 42 COSMIC
COSN30522830 53 COSMIC
COSN24381757 61 COSMIC
COSN30642205 73 COSMIC
COSN19634919 81 COSMIC
COSN13649629 82 COSMIC
COSN31598046 100 COSMIC
COSN31543224 125 COSMIC
COSN30134112 132 COSMIC
COSN16129803 274 COSMIC
COSN31589778 367 COSMIC
COSN30542242 380 COSMIC
COSN31517774 419 COSMIC
COSN31479430 457 COSMIC
COSN31565988 509 COSMIC
COSN5175566 682 COSMIC
COSN8179614 721 COSMIC
COSN31531086 724 COSMIC
COSN8484533 769 COSMIC
COSN20667131 783 COSMIC
COSN20112458 789 COSMIC
COSN21804949 989 COSMIC
COSN32040434 1102 COSMIC
COSN29236152 1218 COSMIC
COSN18988530 1814 COSMIC
COSN31547713 2203 COSMIC
COSN31537961 2254 COSMIC
COSN26670087 2305 COSMIC
COSN1182803 2348 COSMIC
COSN31602512 2522 COSMIC
COSN23312821 2532 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs547080068 1 dbSNP
rs782679631 3 dbSNP
rs781860750 5 dbSNP
rs371395139 9 dbSNP
rs781857425 13 dbSNP
rs782607599 23 dbSNP
rs535980196 28 dbSNP
rs1460328298 30 dbSNP
rs782313224 31 dbSNP
rs782593352 34 dbSNP
rs782273702 39 dbSNP
rs782720833 40 dbSNP
rs375489918 42 dbSNP
rs181760065 43 dbSNP
rs1338711385 60 dbSNP
rs1450437879 63 dbSNP
rs1321028197 66 dbSNP
rs1405262000 66 dbSNP
rs140731040 70 dbSNP
rs544259774 72 dbSNP
rs2292286 81 dbSNP
rs368922366 82 dbSNP
rs942014712 83 dbSNP
rs1243046397 90 dbSNP
rs1209851291 94 dbSNP
rs1037777297 98 dbSNP
rs1449125957 101 dbSNP
rs577513971 103 dbSNP
rs113339493 104 dbSNP
rs1012406513 106 dbSNP
rs1243836954 113 dbSNP
rs1382009435 119 dbSNP
rs1298274659 127 dbSNP
rs1025555510 130 dbSNP
rs541372088 133 dbSNP
rs1405654639 136 dbSNP
rs760544519 138 dbSNP
rs374946026 141 dbSNP
rs1161184272 144 dbSNP
rs574844420 156 dbSNP
rs1390211776 161 dbSNP
rs116894578 162 dbSNP
rs1476639450 163 dbSNP
rs1240775802 169 dbSNP
rs1192919837 183 dbSNP
rs1452453973 185 dbSNP
rs1294195281 195 dbSNP
rs1220477738 209 dbSNP
rs1010564046 221 dbSNP
rs1018061101 223 dbSNP
rs963787266 227 dbSNP
rs1216271237 228 dbSNP
rs782634529 233 dbSNP
rs1269418816 237 dbSNP
rs113261217 242 dbSNP
rs766287042 251 dbSNP
rs983115791 261 dbSNP
rs909784983 267 dbSNP
rs1370646994 280 dbSNP
rs942066991 280 dbSNP
rs1037659785 282 dbSNP
rs868956917 283 dbSNP
rs1417958981 290 dbSNP
rs1167752646 292 dbSNP
rs948143470 293 dbSNP
rs1478575226 295 dbSNP
rs1271450114 297 dbSNP
rs147964631 306 dbSNP
rs1490231793 312 dbSNP
rs1252704068 327 dbSNP
rs1206712924 339 dbSNP
rs906707831 340 dbSNP
rs574494207 346 dbSNP
rs1272230278 349 dbSNP
rs1219694641 356 dbSNP
rs1325428595 359 dbSNP
rs550045107 360 dbSNP
rs1281073790 362 dbSNP
rs1404009902 373 dbSNP
rs1350723035 378 dbSNP
rs1299427404 386 dbSNP
rs1439372968 395 dbSNP
rs894048465 400 dbSNP
rs1328815963 402 dbSNP
rs1470552045 403 dbSNP
rs1431923408 406 dbSNP
rs1174712685 408 dbSNP
rs1010609964 424 dbSNP
rs1480271321 431 dbSNP
rs1408954710 438 dbSNP
rs1179118381 447 dbSNP
rs1017949878 448 dbSNP
rs1479715716 455 dbSNP
rs963666806 463 dbSNP
rs1210741406 464 dbSNP
rs1462584104 481 dbSNP
rs1261091656 488 dbSNP
rs998349147 495 dbSNP
rs1222637486 496 dbSNP
rs372221085 497 dbSNP
rs1221679577 506 dbSNP
rs1308731161 506 dbSNP
rs1371991276 506 dbSNP
rs1284217069 523 dbSNP
rs11543005 526 dbSNP
rs1454040561 530 dbSNP
rs1408936331 536 dbSNP
rs1335193675 537 dbSNP
rs1469630453 539 dbSNP
rs951305197 553 dbSNP
rs982624732 554 dbSNP
rs1346116807 564 dbSNP
rs782197457 575 dbSNP
rs1161558474 579 dbSNP
rs1417494858 581 dbSNP
rs1407420719 600 dbSNP
rs962601198 601 dbSNP
rs1184279888 614 dbSNP
rs1446409330 617 dbSNP
rs1241178846 622 dbSNP
rs185885219 634 dbSNP
rs916589592 635 dbSNP
rs1262206047 642 dbSNP
rs1213232459 647 dbSNP
rs948028674 648 dbSNP
rs1315952419 650 dbSNP
rs1290053298 658 dbSNP
rs190480828 665 dbSNP
rs1247497151 667 dbSNP
rs565560894 673 dbSNP
rs1313593633 689 dbSNP
rs1452461002 696 dbSNP
rs1363107056 703 dbSNP
rs1290982194 707 dbSNP
rs782617166 713 dbSNP
rs536273297 716 dbSNP
rs181559669 717 dbSNP
rs569454573 720 dbSNP
rs1344794236 721 dbSNP
rs1164346776 723 dbSNP
rs782242486 728 dbSNP
rs928052455 736 dbSNP
rs1182921405 749 dbSNP
rs935526325 750 dbSNP
rs1263658397 753 dbSNP
rs1184557819 758 dbSNP
rs537246717 760 dbSNP
rs1292023816 767 dbSNP
rs1224201328 771 dbSNP
rs1356645978 771 dbSNP
rs147082900 773 dbSNP
rs11269259 784 dbSNP
rs34611478 785 dbSNP
rs376092037 789 dbSNP
rs558731839 790 dbSNP
rs894100633 796 dbSNP
rs1363808780 802 dbSNP
rs140067355 805 dbSNP
rs1462493740 811 dbSNP
rs260086 824 dbSNP
rs1168117953 825 dbSNP
rs1039942871 827 dbSNP
rs561282071 832 dbSNP
rs1201150983 841 dbSNP
rs899511511 843 dbSNP
rs997836078 850 dbSNP
rs1029858204 852 dbSNP
rs886856799 853 dbSNP
rs1195835756 855 dbSNP
rs1481273281 857 dbSNP
rs1253615666 861 dbSNP
rs1225828702 863 dbSNP
rs528697423 869 dbSNP
rs1317692982 870 dbSNP
rs1284267797 880 dbSNP
rs546859742 883 dbSNP
rs1343870712 886 dbSNP
rs1302676352 897 dbSNP
rs553306681 904 dbSNP
rs1398667879 906 dbSNP
rs868940208 908 dbSNP
rs1429808045 909 dbSNP
rs1178315450 911 dbSNP
rs752228536 919 dbSNP
rs112735738 930 dbSNP
rs142944374 931 dbSNP
rs151090616 932 dbSNP
rs879967624 951 dbSNP
rs557485637 954 dbSNP
rs1457703525 965 dbSNP
rs1022814128 966 dbSNP
rs1205936002 968 dbSNP
rs1264217562 968 dbSNP
rs1321734921 976 dbSNP
rs35268040 984 dbSNP
rs982121238 989 dbSNP
rs1239949939 993 dbSNP
rs1337624144 1000 dbSNP
rs1304941520 1004 dbSNP
rs1390815832 1005 dbSNP
rs1406685946 1022 dbSNP
rs928071860 1023 dbSNP
rs935425759 1035 dbSNP
rs988590718 1037 dbSNP
rs543601078 1039 dbSNP
rs1405029312 1042 dbSNP
rs1158793165 1050 dbSNP
rs1470927887 1055 dbSNP
rs1361625829 1057 dbSNP
rs1180464761 1058 dbSNP
rs1439665894 1074 dbSNP
rs946836771 1077 dbSNP
rs186278843 1082 dbSNP
rs1460285540 1086 dbSNP
rs1278288428 1087 dbSNP
rs1206003334 1101 dbSNP
rs1353106226 1117 dbSNP
rs1039995464 1125 dbSNP
rs781940152 1126 dbSNP
rs1239485280 1132 dbSNP
rs933687720 1140 dbSNP
rs1450272669 1157 dbSNP
rs1050783841 1173 dbSNP
rs1339673026 1183 dbSNP
rs140153935 1185 dbSNP
rs777397513 1191 dbSNP
rs1382286666 1192 dbSNP
rs1157535661 1197 dbSNP
rs1424774529 1199 dbSNP
rs1386519737 1205 dbSNP
rs71403425 1206 dbSNP
rs540946065 1207 dbSNP
rs1194307919 1208 dbSNP
rs1449000742 1213 dbSNP
rs1259938662 1215 dbSNP
rs559634715 1220 dbSNP
rs529632524 1221 dbSNP
rs1022866440 1223 dbSNP
rs1270596653 1226 dbSNP
rs1355557622 1226 dbSNP
rs143895757 1226 dbSNP
rs1432611041 1227 dbSNP
rs781868547 1227 dbSNP
rs982559812 1228 dbSNP
rs1405108989 1229 dbSNP
rs1035029680 1233 dbSNP
rs1161127402 1234 dbSNP
rs1423338390 1241 dbSNP
rs547828967 1242 dbSNP
rs569365975 1243 dbSNP
rs1476609330 1244 dbSNP
rs1371628897 1253 dbSNP
rs1193229494 1259 dbSNP
rs1490571886 1260 dbSNP
rs988235303 1261 dbSNP
rs1220315636 1262 dbSNP
rs1451017013 1290 dbSNP
rs1273658807 1291 dbSNP
rs1216217192 1311 dbSNP
rs915303838 1343 dbSNP
rs946889033 1344 dbSNP
rs530532175 1345 dbSNP
rs1346971336 1356 dbSNP
rs1300798347 1363 dbSNP
rs1435153936 1364 dbSNP
rs1354569582 1377 dbSNP
rs1330149077 1389 dbSNP
rs1412074608 1394 dbSNP
rs782128660 1395 dbSNP
rs191130783 1403 dbSNP
rs921556117 1404 dbSNP
rs559507833 1409 dbSNP
rs782728036 1411 dbSNP
rs1197477225 1412 dbSNP
rs1233465154 1413 dbSNP
rs1206555980 1415 dbSNP
rs1257231602 1415 dbSNP
rs934264409 1415 dbSNP
rs1204034033 1438 dbSNP
rs1281007491 1439 dbSNP
rs1218205060 1446 dbSNP
rs1051751470 1448 dbSNP
rs7495210 1455 dbSNP
rs886792519 1456 dbSNP
rs939659341 1459 dbSNP
rs1038108805 1461 dbSNP
rs1398702255 1463 dbSNP
rs898237661 1470 dbSNP
rs1408709403 1474 dbSNP
rs570980793 1474 dbSNP
rs1044206128 1478 dbSNP
rs781837384 1487 dbSNP
rs3134588 1488 dbSNP
rs1408889223 1492 dbSNP
rs1178992242 1495 dbSNP
rs1031976609 1496 dbSNP
rs115011190 1501 dbSNP
rs1237517122 1502 dbSNP
rs568779343 1508 dbSNP
rs1009550402 1514 dbSNP
rs1462487919 1514 dbSNP
rs1260956270 1515 dbSNP
rs535800600 1518 dbSNP
rs1209055423 1521 dbSNP
rs1317138451 1529 dbSNP
rs1285797387 1535 dbSNP
rs1221555297 1540 dbSNP
rs1022415236 1545 dbSNP
rs968125431 1548 dbSNP
rs1375459952 1551 dbSNP
rs3803474 1552 dbSNP
rs1453928059 1570 dbSNP
rs1385455268 1573 dbSNP
rs1301448886 1576 dbSNP
rs780401517 1578 dbSNP
rs1345986671 1581 dbSNP
rs921452729 1586 dbSNP
rs1417972551 1595 dbSNP
rs1379694403 1602 dbSNP
rs1164144045 1609 dbSNP
rs1446355065 1611 dbSNP
rs575772826 1615 dbSNP
rs955699896 1616 dbSNP
rs546339928 1625 dbSNP
rs182655895 1628 dbSNP
rs1352339543 1629 dbSNP
rs576946547 1632 dbSNP
rs782276354 1643 dbSNP
rs541260912 1644 dbSNP
rs186658019 1647 dbSNP
rs1311090097 1648 dbSNP
rs1395831309 1649 dbSNP
rs114159911 1650 dbSNP
rs1290860580 1651 dbSNP
rs919716594 1665 dbSNP
rs948474374 1666 dbSNP
rs1303831353 1679 dbSNP
rs1426519855 1685 dbSNP
rs1044089442 1692 dbSNP
rs1366625428 1695 dbSNP
rs1163931643 1699 dbSNP
rs907046731 1700 dbSNP
rs1003094372 1702 dbSNP
rs782548093 1729 dbSNP
rs1191086890 1730 dbSNP
rs769231586 1738 dbSNP
rs34524139 1742 dbSNP
rs1224038436 1757 dbSNP
rs891692666 1759 dbSNP
rs3210942 1766 dbSNP
rs1244609551 1769 dbSNP
rs1308459986 1770 dbSNP
rs530497038 1774 dbSNP
rs968008496 1779 dbSNP
rs1217102587 1782 dbSNP
rs996948984 1784 dbSNP
rs1406869936 1792 dbSNP
rs551966966 1796 dbSNP
rs955592389 1798 dbSNP
rs570564326 1800 dbSNP
rs781974119 1806 dbSNP
rs781973059 1807 dbSNP
rs1462385601 1809 dbSNP
rs1356124200 1812 dbSNP
rs1168271529 1816 dbSNP
rs1477318185 1817 dbSNP
rs1429580200 1820 dbSNP
rs1201081153 1827 dbSNP
rs908828081 1829 dbSNP
rs1265985943 1830 dbSNP
rs868911193 1832 dbSNP
rs191068419 1834 dbSNP
rs974257085 1835 dbSNP
rs547172686 1845 dbSNP
rs1284202618 1846 dbSNP
rs1225511869 1852 dbSNP
rs1329435232 1853 dbSNP
rs782255736 1854 dbSNP
rs1391964777 1861 dbSNP
rs1375405618 1862 dbSNP
rs948361329 1864 dbSNP
rs1464932729 1868 dbSNP
rs1406455796 1873 dbSNP
rs1178154280 1904 dbSNP
rs1464219249 1918 dbSNP
rs1376640895 1920 dbSNP
rs1181863727 1921 dbSNP
rs568617482 1922 dbSNP
rs782713568 1924 dbSNP
rs1240598671 1926 dbSNP
rs1177273105 1927 dbSNP
rs1457604655 1929 dbSNP
rs1264081792 1930 dbSNP
rs1202463061 1942 dbSNP
rs536170272 1952 dbSNP
rs1239886570 1955 dbSNP
rs1255529698 1955 dbSNP
rs1355890469 1958 dbSNP
rs1306992037 1959 dbSNP
rs1044169119 1965 dbSNP
rs566514584 1967 dbSNP
rs928353694 1972 dbSNP
rs1393967134 1991 dbSNP
rs938554558 1994 dbSNP
rs1158741427 1995 dbSNP
rs1401022171 1995 dbSNP
rs13853 2005 dbSNP
rs782029410 2034 dbSNP
rs891589787 2042 dbSNP
rs1377876667 2053 dbSNP
rs947296557 2054 dbSNP
rs1042967892 2076 dbSNP
rs1244209668 2080 dbSNP
rs782045365 2081 dbSNP
rs1190016533 2086 dbSNP
rs1440960492 2090 dbSNP
rs1255772690 2102 dbSNP
rs1205866879 2106 dbSNP
rs1355958878 2108 dbSNP
rs782703637 2118 dbSNP
rs996833107 2122 dbSNP
rs1239421854 2126 dbSNP
rs1360025839 2128 dbSNP
rs781953056 2133 dbSNP
rs1242369162 2146 dbSNP
rs1339612666 2149 dbSNP
rs1318573967 2150 dbSNP
rs1401401222 2153 dbSNP
rs891197474 2160 dbSNP
rs569252426 2166 dbSNP
rs773508196 2172 dbSNP
rs1386386005 2174 dbSNP
rs1472015003 2175 dbSNP
rs1368196150 2180 dbSNP
rs1016179092 2181 dbSNP
rs961491098 2201 dbSNP
rs782488929 2202 dbSNP
rs1489391113 2205 dbSNP
rs974308186 2206 dbSNP
rs117635910 2207 dbSNP
rs782762579 2208 dbSNP
rs1207921895 2209 dbSNP
rs1355396314 2217 dbSNP
rs1220163147 2226 dbSNP
rs1270539088 2226 dbSNP
rs747237239 2230 dbSNP
rs980160757 2231 dbSNP
rs1277077022 2236 dbSNP
rs928436188 2237 dbSNP
rs938435347 2238 dbSNP
rs988546931 2244 dbSNP
rs1404078001 2246 dbSNP
rs1390545281 2250 dbSNP
rs781872130 2251 dbSNP
rs1421784619 2252 dbSNP
rs1193165012 2254 dbSNP
rs1480807986 2263 dbSNP
rs1248473838 2264 dbSNP
rs150327415 2265 dbSNP
rs1450959877 2269 dbSNP
rs1273502634 2284 dbSNP
rs573334238 2292 dbSNP
rs1257069539 2294 dbSNP
rs1223682876 2299 dbSNP
rs1043019278 2305 dbSNP
rs900407961 2306 dbSNP
rs932703249 2314 dbSNP
rs1331010458 2315 dbSNP
rs1332572446 2317 dbSNP
rs183213023 2321 dbSNP
rs891089011 2325 dbSNP
rs1170255635 2328 dbSNP
rs146414140 2330 dbSNP
rs782539460 2331 dbSNP
rs1415243028 2333 dbSNP
rs1427438939 2336 dbSNP
rs1189522673 2339 dbSNP
rs574357894 2343 dbSNP
rs1233411837 2357 dbSNP
rs1180393519 2375 dbSNP
rs140827594 2379 dbSNP
rs1237324776 2381 dbSNP
rs897347218 2386 dbSNP
rs1203975454 2389 dbSNP
rs563273911 2396 dbSNP
rs187659522 2397 dbSNP
rs1218152927 2398 dbSNP
rs200245044 2408 dbSNP
rs1310634827 2411 dbSNP
rs1350711825 2411 dbSNP
rs970273977 2430 dbSNP
rs979829622 2432 dbSNP
rs192874457 2442 dbSNP
rs1331091768 2443 dbSNP
rs1449084466 2450 dbSNP
rs563976783 2452 dbSNP
rs1361093636 2453 dbSNP
rs1174165403 2466 dbSNP
rs184998991 2470 dbSNP
rs1380929012 2475 dbSNP
rs770804843 2479 dbSNP
rs1237380887 2481 dbSNP
rs1183948023 2483 dbSNP
rs1484083582 2494 dbSNP
rs988986330 2497 dbSNP
rs1208905985 2498 dbSNP
rs912969096 2518 dbSNP
rs947232687 2521 dbSNP
rs776503954 2524 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23336.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ggccaggcauguuuGAGACGUc 5'
                        ||||||| 
Target 5' -----------cuuCUCUGCAc 3'
 		1 - 11
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000560674.1 | 3UTR | CUUCUCUGCACCUUAUCCCUUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC -0.347 0.18 -0.400 0.14 9 Click to see details
LUSC -0.463 0.27 -0.200 0.4 4 Click to see details
HNSC -0.155 0.32 -0.136 0.35 11 Click to see details
HNSC -0.155 0.32 -0.136 0.35 11 Click to see details
HNSC -0.155 0.32 -0.136 0.35 11 Click to see details
HNSC -0.155 0.32 -0.136 0.35 11 Click to see details
HNSC -0.155 0.32 -0.136 0.35 11 Click to see details
HNSC -0.155 0.32 -0.136 0.35 11 Click to see details
HNSC -0.155 0.32 -0.136 0.35 11 Click to see details
HNSC -0.155 0.32 -0.136 0.35 11 Click to see details
HNSC -0.155 0.32 -0.136 0.35 11 Click to see details
HNSC -0.155 0.32 -0.136 0.35 11 Click to see details
86 hsa-miR-3678-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT074327 TNRC6A trinucleotide repeat containing 6A 2 10
MIRT107705 CLTA clathrin light chain A 2 2
MIRT114113 AGO1 argonaute 1, RISC catalytic component 2 2
MIRT155293 IFNAR2 interferon alpha and beta receptor subunit 2 2 4
MIRT159171 NRBP1 nuclear receptor binding protein 1 2 2
MIRT185795 ZNF678 zinc finger protein 678 2 2
MIRT282672 SYNM synemin 2 2
MIRT294386 ZNF264 zinc finger protein 264 2 2
MIRT295818 CHMP4B charged multivesicular body protein 4B 2 2
MIRT332777 CAPRIN1 cell cycle associated protein 1 2 4
MIRT334112 PPP6R3 protein phosphatase 6 regulatory subunit 3 2 2
MIRT340971 IPO5 importin 5 2 2
MIRT354679 CDV3 CDV3 homolog 2 2
MIRT366662 PLP2 proteolipid protein 2 2 2
MIRT404272 PLEKHA8 pleckstrin homology domain containing A8 2 2
MIRT447536 RNF165 ring finger protein 165 2 2
MIRT449139 UQCRB ubiquinol-cytochrome c reductase binding protein 2 2
MIRT451301 LGALS3BP galectin 3 binding protein 2 2
MIRT451488 FOPNL FGFR1OP N-terminal like 2 2
MIRT455198 GNL1 G protein nucleolar 1 (putative) 2 2
MIRT459215 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT461764 MPDU1 mannose-P-dolichol utilization defect 1 2 2
MIRT463273 ZFX zinc finger protein, X-linked 2 2
MIRT464862 UBB ubiquitin B 2 8
MIRT464950 TWIST1 twist family bHLH transcription factor 1 2 2
MIRT467378 SON SON DNA binding protein 2 4
MIRT469282 RHOA ras homolog family member A 2 2
MIRT470293 PPTC7 PTC7 protein phosphatase homolog 2 2
MIRT470639 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT477163 FABP3 fatty acid binding protein 3 2 2
MIRT477686 EFHD2 EF-hand domain family member D2 2 2
MIRT479725 CCNF cyclin F 2 2
MIRT481726 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT485673 CCDC64 BICD family like cargo adaptor 1 2 2
MIRT498280 PADI2 peptidyl arginine deiminase 2 2 2
MIRT499921 GPX8 glutathione peroxidase 8 (putative) 2 2
MIRT503616 SLC25A36 solute carrier family 25 member 36 2 4
MIRT506927 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT507348 FAM129A family with sequence similarity 129 member A 2 6
MIRT508265 DYNLL2 dynein light chain LC8-type 2 2 4
MIRT508284 YES1 YES proto-oncogene 1, Src family tyrosine kinase 2 4
MIRT509353 COPS8 COP9 signalosome subunit 8 2 2
MIRT510892 RAB1A RAB1A, member RAS oncogene family 2 4
MIRT511882 GAS1 growth arrest specific 1 2 6
MIRT511990 E2F1 E2F transcription factor 1 2 4
MIRT512239 ARPP19 cAMP regulated phosphoprotein 19 2 4
MIRT512392 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 4
MIRT514086 EPS15L1 epidermal growth factor receptor pathway substrate 15 like 1 2 6
MIRT514358 UBBP4 ubiquitin B pseudogene 4 2 6
MIRT523149 HNRNPU heterogeneous nuclear ribonucleoprotein U 2 2
MIRT525511 FSIP2 fibrous sheath interacting protein 2 2 2
MIRT526333 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT529962 ZNF71 zinc finger protein 71 2 2
MIRT530337 GABRB3 gamma-aminobutyric acid type A receptor beta3 subunit 2 2
MIRT530884 PHOX2A paired like homeobox 2a 2 2
MIRT533097 YOD1 YOD1 deubiquitinase 2 2
MIRT533250 VCAM1 vascular cell adhesion molecule 1 2 2
MIRT534786 RAB8B RAB8B, member RAS oncogene family 2 2
MIRT537917 DSTYK dual serine/threonine and tyrosine protein kinase 2 2
MIRT547799 JARID2 jumonji and AT-rich interaction domain containing 2 2 2
MIRT548714 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT555509 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT555984 NFYB nuclear transcription factor Y subunit beta 2 2
MIRT557942 FAM222B family with sequence similarity 222 member B 2 2
MIRT560830 ZNF786 zinc finger protein 786 2 2
MIRT562720 ZNF714 zinc finger protein 714 2 2
MIRT565337 TMEM104 transmembrane protein 104 2 2
MIRT614453 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT639474 SLC6A4 solute carrier family 6 member 4 2 2
MIRT644056 IQCE IQ motif containing E 2 2
MIRT651652 VWA1 von Willebrand factor A domain containing 1 2 2
MIRT651866 UNC119B unc-119 lipid binding chaperone B 2 2
MIRT653490 SLC43A2 solute carrier family 43 member 2 2 2
MIRT657039 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT657985 GAN gigaxonin 2 2
MIRT672117 ATP6V0A2 ATPase H+ transporting V0 subunit a2 2 2
MIRT683583 GSTCD glutathione S-transferase C-terminal domain containing 2 2
MIRT688689 CPS1 carbamoyl-phosphate synthase 1 2 2
MIRT695375 NSA2 NSA2, ribosome biogenesis homolog 2 2
MIRT696351 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT700614 PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 2 2
MIRT703512 FKBP15 FK506 binding protein 15 2 2
MIRT705051 C5orf15 chromosome 5 open reading frame 15 2 2
MIRT705180 BTG1 BTG anti-proliferation factor 1 2 2
MIRT709409 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT721053 DCC DCC netrin 1 receptor 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3678-3p Platinum 23939 resistant tissue
hsa-miR-3678-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3678-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-3678-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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