miRTarBase - #MIRT285546


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pre-miRNA Information
pre-miRNA hsa-mir-6876   
Genomic Coordinates chr8: 25345402 - 25345474
Description Homo sapiens miR-6876 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6876-5p
Sequence 6| CAGGAAGGAGACAGGCAGUUCA |27
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs748354537 2 dbSNP
rs1288867641 4 dbSNP
rs1377863527 8 dbSNP
rs1226097873 13 dbSNP
rs1314505872 15 dbSNP
rs538773180 16 dbSNP
rs1257978718 17 dbSNP
rs556769953 17 dbSNP
rs766054574 18 dbSNP
rs749839874 21 dbSNP
rs1209003267 22 dbSNP
Putative Targets

Gene Information
Gene Symbol CDT1   
Synonyms DUP, RIS2
Description chromatin licensing and DNA replication factor 1
Transcript NM_030928   
Expression
Putative miRNA Targets on CDT1
3'UTR of CDT1
(miRNA target sites are highlighted)		 
>CDT1|NM_030928|3'UTR
   1 GCCTGGGGGCCACTGTGGACAGACGTGGGCTTCAGAAGCTCGCTGGCCTGGGCCCACCAGCATTTTCTTTTATGAACATG
  81 ATACACTTTGGCCTTCCTTTCCCCAGCGCCCCTGAGGGCCAGAGGCAGATGTGGGCTGCAGGCTGCACAGCCCGAGGGTC
 161 TCTGGCTGCGGGCGGTGGGCCCCTTCATGGGGCTCACCTGGTGGATTCACATTAAACCGGTTTCTGTGGGCACCTCTGTC
 241 CTTGCTGCTGGTGGGGAAGGGAAGCCAGATCCAGCACCCCCTGGGGGGCCATCGGGAGTGTGGCTGGGGGTGAAGGGGGC
 321 TCTGTGGCAATATGGGGTTGGGTAGTGTGGGTGGCAGGCCATCCCCTCTAATCTTGGAACCTCTGAATATGGGACCTCCC
 401 ACAGCAAAGGGTGACTTTTGTCATTAAGAAAGACTGGGGTGGGTGTGGTGGCTCACGCCTGTAACCCCAGCACTTTGGGA
 481 GGCCAAGGTGGGCAGATCACGAGGTCAAGAGATCGAGACCATCCTGGCGAACATGGTGAAACCCCATCTCTACTAAAAAT
 561 ACAAAAAATTAGCCGGGTGTGGTGGTGGGCACCTGTCGTCCCAGCTACTAGGGAGGCTGAGGCAGGAGAATGGTGTGAAC
 641 CCAGGAGGCACAGCTTGCAGTGAGCGAAGATCGCACCACTGCACGCACTCCAGCCTGGGTGACAGAGCGAGACTCCGTCT
 721 CAAAAAAAAAAATTTCAAGACTGGAGAGGTGATCCTGAATTGTCCAGCTACGCCCCATGTCATCACAGGGCCTTCATGAC
 801 AGGGCCAGAGCCAGCCAGCTTTGAAGACGCGGCCCTGCCCCGACACAGGCAGCCTGGAGAAGCTGGGCAGGACAAGTAGG
 881 ACATCCCTGGAGCCTCCAGAAGGGACTGGCCTCTGCCCACACCTTGACTTCAGTATTTCTGACCTCCTAAACTCTAATAA
 961 AGTCATGCTTACAGCCACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
1041 AAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acUUG-AC---G-GACAGAGGAAGGAc 5'
            ||| ||   | || |  ||||||| 
Target 5' tgAACATGATACACTTTGGCCTTCCTt 3'
 73 - 99 148.00 -14.50
2 
miRNA  3' acuugacGGACAGAGGAAGGAc 5'
                 ||| | ||||| || 
Target 5' gtgggcaCCTCTGTCCTTGCTg 3'
 226 - 247 127.00 -18.60
3 
miRNA  3' acUUGACG---GACA---GAGGAAGGAc 5'
            ::||||   | ||   | ||||| | 
Target 5' ctGGCTGCGGGCGGTGGGCCCCTTCATg 3'
 162 - 189 120.00 -16.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
128663 7 ClinVar
281564 10 ClinVar
COSN28854912 13 COSMIC
COSN28854930 14 COSMIC
COSN29463061 43 COSMIC
COSN30117011 61 COSMIC
COSN6648275 93 COSMIC
COSN32152290 237 COSMIC
COSN23301981 311 COSMIC
COSN24966804 327 COSMIC
COSN32152291 722 COSMIC
COSN7158457 910 COSMIC
COSN7158458 927 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1324137708 1 dbSNP
rs1038606241 2 dbSNP
rs1258478050 3 dbSNP
rs1251945180 5 dbSNP
rs3218723 7 dbSNP
rs999339323 8 dbSNP
rs1176736517 9 dbSNP
rs371269045 10 dbSNP
rs11548244 11 dbSNP
rs757852200 13 dbSNP
rs377463829 15 dbSNP
rs1006970880 16 dbSNP
rs746266376 17 dbSNP
rs1413530181 20 dbSNP
rs1170578036 21 dbSNP
rs770234345 23 dbSNP
rs1018729980 24 dbSNP
rs775620005 25 dbSNP
rs80302516 26 dbSNP
rs373891152 27 dbSNP
rs761818537 30 dbSNP
rs1355211890 35 dbSNP
rs991954677 37 dbSNP
rs78831570 42 dbSNP
rs368053717 43 dbSNP
rs3743548 44 dbSNP
rs909944366 45 dbSNP
rs1296515457 47 dbSNP
rs753501287 48 dbSNP
rs760593797 51 dbSNP
rs781239505 51 dbSNP
rs1263595217 55 dbSNP
rs532373966 57 dbSNP
rs747906511 58 dbSNP
rs112314329 59 dbSNP
rs934239544 63 dbSNP
rs1270789254 65 dbSNP
rs1050749897 66 dbSNP
rs1318212487 68 dbSNP
rs1036414709 69 dbSNP
rs897408395 70 dbSNP
rs550745740 72 dbSNP
rs930179573 79 dbSNP
rs1318175876 80 dbSNP
rs1051298989 81 dbSNP
rs1043881642 86 dbSNP
rs562482200 88 dbSNP
rs15829 93 dbSNP
rs189620919 97 dbSNP
rs896439122 98 dbSNP
rs183396627 103 dbSNP
rs775531035 108 dbSNP
rs1031379358 109 dbSNP
rs534236945 111 dbSNP
rs1453325504 112 dbSNP
rs763139056 117 dbSNP
rs956629610 119 dbSNP
rs552484851 120 dbSNP
rs1457846885 123 dbSNP
rs1024789712 126 dbSNP
rs1212452288 129 dbSNP
rs112876071 131 dbSNP
rs1270046354 133 dbSNP
rs980987094 134 dbSNP
rs538091252 139 dbSNP
rs1017441593 140 dbSNP
rs867864294 141 dbSNP
rs962787172 142 dbSNP
rs1177624415 147 dbSNP
rs1301914440 149 dbSNP
rs749456835 151 dbSNP
rs963420131 154 dbSNP
rs556678610 155 dbSNP
rs971765214 156 dbSNP
rs150410264 159 dbSNP
rs535919299 170 dbSNP
rs1051329869 171 dbSNP
rs912764771 174 dbSNP
rs942893395 175 dbSNP
rs911449266 176 dbSNP
rs1478753394 193 dbSNP
rs1799825 202 dbSNP
rs572508729 204 dbSNP
rs1043361337 215 dbSNP
rs903937862 219 dbSNP
rs925065384 220 dbSNP
rs1350548873 221 dbSNP
rs1001321963 226 dbSNP
rs1388318970 227 dbSNP
rs1386424702 229 dbSNP
rs1377727714 241 dbSNP
rs1052487403 242 dbSNP
rs1281415157 243 dbSNP
rs111978266 246 dbSNP
rs1335345134 251 dbSNP
rs1013487624 252 dbSNP
rs1013401919 254 dbSNP
rs1045016150 255 dbSNP
rs558937894 261 dbSNP
rs1277678073 262 dbSNP
rs1001943980 269 dbSNP
rs1381590475 273 dbSNP
rs969253947 278 dbSNP
rs1175020228 279 dbSNP
rs1319151925 280 dbSNP
rs577199243 282 dbSNP
rs1237657379 283 dbSNP
rs1221016306 287 dbSNP
rs1189199785 289 dbSNP
rs1016933087 292 dbSNP
rs1016477910 294 dbSNP
rs963195310 295 dbSNP
rs1488396672 296 dbSNP
rs1025790055 299 dbSNP
rs972220437 299 dbSNP
rs1222104019 301 dbSNP
rs116408076 303 dbSNP
rs986897492 306 dbSNP
rs1190817199 307 dbSNP
rs1353322319 308 dbSNP
rs1422310039 309 dbSNP
rs1478070257 312 dbSNP
rs772432300 313 dbSNP
rs964327531 316 dbSNP
rs1172819690 321 dbSNP
rs764389903 323 dbSNP
rs979545032 325 dbSNP
rs1457257541 326 dbSNP
rs1413909964 334 dbSNP
rs987103531 336 dbSNP
rs145184038 338 dbSNP
rs1255813162 343 dbSNP
rs1187742400 344 dbSNP
rs1488838852 345 dbSNP
rs1393092629 346 dbSNP
rs942907304 347 dbSNP
rs1214292654 348 dbSNP
rs1446486645 352 dbSNP
rs1039879791 359 dbSNP
rs1235330811 360 dbSNP
rs925434465 364 dbSNP
rs115858231 365 dbSNP
rs541874140 371 dbSNP
rs1292929721 377 dbSNP
rs1218974999 378 dbSNP
rs1052458561 379 dbSNP
rs1297590731 379 dbSNP
rs1430009946 380 dbSNP
rs1459530808 381 dbSNP
rs935099623 381 dbSNP
rs1416658106 393 dbSNP
rs1170951796 394 dbSNP
rs1429422742 397 dbSNP
rs1402393209 400 dbSNP
rs761292987 401 dbSNP
rs1321465643 410 dbSNP
rs1245935749 412 dbSNP
rs146065747 416 dbSNP
rs949207132 419 dbSNP
rs1272709303 421 dbSNP
rs753754884 423 dbSNP
rs1361082415 424 dbSNP
rs1044881208 426 dbSNP
rs1046345778 429 dbSNP
rs1213893062 431 dbSNP
rs1214012048 435 dbSNP
rs1305569448 436 dbSNP
rs1261835039 437 dbSNP
rs905149349 437 dbSNP
rs1393109963 438 dbSNP
rs186313212 445 dbSNP
rs1002524949 446 dbSNP
rs190721711 447 dbSNP
rs898475997 449 dbSNP
rs551747679 453 dbSNP
rs1196062195 454 dbSNP
rs537106948 457 dbSNP
rs1252519653 458 dbSNP
rs762627008 459 dbSNP
rs754665812 466 dbSNP
rs1203500502 467 dbSNP
rs1026079711 468 dbSNP
rs555194801 471 dbSNP
rs573548716 476 dbSNP
rs1369601874 478 dbSNP
rs183484043 483 dbSNP
rs979690099 485 dbSNP
rs1032984573 486 dbSNP
rs1461742382 487 dbSNP
rs1418021704 489 dbSNP
rs956413399 490 dbSNP
rs1361229110 495 dbSNP
rs1159992157 496 dbSNP
rs987771104 499 dbSNP
rs531984886 501 dbSNP
rs976053162 502 dbSNP
rs1379021439 505 dbSNP
rs534311158 509 dbSNP
rs568608827 510 dbSNP
rs535659067 515 dbSNP
rs1237493700 516 dbSNP
rs1284933592 522 dbSNP
rs866970374 523 dbSNP
rs941964140 524 dbSNP
rs936849200 529 dbSNP
rs375338425 530 dbSNP
rs566173203 533 dbSNP
rs777170519 535 dbSNP
rs1182378313 536 dbSNP
rs949439936 538 dbSNP
rs1046417229 539 dbSNP
rs1244738782 541 dbSNP
rs1008255836 543 dbSNP
rs1437655222 545 dbSNP
rs1475678671 546 dbSNP
rs905191700 547 dbSNP
rs900017135 548 dbSNP
rs756061607 550 dbSNP
rs1485239715 552 dbSNP
rs1001413887 555 dbSNP
rs199548811 561 dbSNP
rs371535130 562 dbSNP
rs937964441 562 dbSNP
rs188631314 563 dbSNP
rs1009275420 569 dbSNP
rs899051423 570 dbSNP
rs1402685774 571 dbSNP
rs558141521 575 dbSNP
rs192801582 576 dbSNP
rs1484191903 579 dbSNP
rs890217791 580 dbSNP
rs1008642449 582 dbSNP
rs1396910524 584 dbSNP
rs1467002776 585 dbSNP
rs183188911 588 dbSNP
rs980496472 589 dbSNP
rs964719504 590 dbSNP
rs978423591 592 dbSNP
rs556100687 594 dbSNP
rs1260406078 596 dbSNP
rs1033027239 597 dbSNP
rs186930018 598 dbSNP
rs1225132131 599 dbSNP
rs1271175398 600 dbSNP
rs191491646 602 dbSNP
rs541636746 605 dbSNP
rs944018882 605 dbSNP
rs914066780 606 dbSNP
rs1441638368 607 dbSNP
rs879693248 610 dbSNP
rs559857605 611 dbSNP
rs899881631 612 dbSNP
rs1396905692 613 dbSNP
rs1169479835 624 dbSNP
rs527345515 635 dbSNP
rs926671128 636 dbSNP
rs1456253073 637 dbSNP
rs1194194559 638 dbSNP
rs938021715 640 dbSNP
rs545399352 641 dbSNP
rs1197724875 644 dbSNP
rs1238574756 646 dbSNP
rs1037682128 651 dbSNP
rs899080635 652 dbSNP
rs1009809513 654 dbSNP
rs1024667436 655 dbSNP
rs970397717 656 dbSNP
rs1424531262 658 dbSNP
rs929173129 663 dbSNP
rs1033441531 666 dbSNP
rs1047628614 667 dbSNP
rs1465586020 668 dbSNP
rs1332399026 669 dbSNP
rs890289934 670 dbSNP
rs553034468 671 dbSNP
rs1008681629 672 dbSNP
rs1017785219 673 dbSNP
rs757410962 674 dbSNP
rs900226612 676 dbSNP
rs1389397007 677 dbSNP
rs115513771 678 dbSNP
rs1174175392 682 dbSNP
rs837760 685 dbSNP
rs958318279 686 dbSNP
rs550487033 687 dbSNP
rs1315925379 688 dbSNP
rs1234188071 691 dbSNP
rs562224772 695 dbSNP
rs113599906 701 dbSNP
rs1439401275 702 dbSNP
rs547999803 702 dbSNP
rs1219616154 704 dbSNP
rs1350742208 706 dbSNP
rs1021104366 709 dbSNP
rs1488945056 710 dbSNP
rs1053984946 712 dbSNP
rs566185448 717 dbSNP
rs1009712967 718 dbSNP
rs1477744131 719 dbSNP
rs1046693587 721 dbSNP
rs1001878005 722 dbSNP
rs796277561 722 dbSNP
rs906747720 722 dbSNP
rs1033757702 732 dbSNP
rs1491488430 732 dbSNP
rs201931778 733 dbSNP
rs898945207 733 dbSNP
rs982214757 734 dbSNP
rs1411665860 736 dbSNP
rs1189034370 737 dbSNP
rs994980393 742 dbSNP
rs1255948387 743 dbSNP
rs1026042833 744 dbSNP
rs1404003025 745 dbSNP
rs1447644497 747 dbSNP
rs1162224428 752 dbSNP
rs1348899297 757 dbSNP
rs1286516352 765 dbSNP
rs539893219 772 dbSNP
rs34952796 773 dbSNP
rs959443584 773 dbSNP
rs973820307 774 dbSNP
rs1234833078 778 dbSNP
rs551818544 779 dbSNP
rs1431475168 789 dbSNP
rs964595723 790 dbSNP
rs8191509 793 dbSNP
rs1047659656 797 dbSNP
rs1399306007 797 dbSNP
rs1278818398 799 dbSNP
rs1341169712 801 dbSNP
rs911784858 803 dbSNP
rs8191508 807 dbSNP
rs556236747 812 dbSNP
rs537035674 813 dbSNP
rs75008893 815 dbSNP
rs8191507 815 dbSNP
rs989989199 816 dbSNP
rs781530983 819 dbSNP
rs1464501030 827 dbSNP
rs1038827943 828 dbSNP
rs183683347 829 dbSNP
rs906819599 830 dbSNP
rs938250501 831 dbSNP
rs999943599 840 dbSNP
rs574639635 842 dbSNP
rs535649386 843 dbSNP
rs1424897602 847 dbSNP
rs1371114676 849 dbSNP
rs1054571098 851 dbSNP
rs1165144345 854 dbSNP
rs1459611868 858 dbSNP
rs891445031 863 dbSNP
rs553505468 866 dbSNP
rs1358046277 867 dbSNP
rs1009805345 871 dbSNP
rs1318437729 872 dbSNP
rs1328074539 874 dbSNP
rs571831275 876 dbSNP
rs1283317633 881 dbSNP
rs1187240419 882 dbSNP
rs1448924568 884 dbSNP
rs1383344396 885 dbSNP
rs545460844 896 dbSNP
rs747459949 903 dbSNP
rs1195699445 915 dbSNP
rs1026030809 919 dbSNP
rs970928322 929 dbSNP
rs14743 930 dbSNP
rs1004119379 931 dbSNP
rs1204909956 932 dbSNP
rs1008725091 934 dbSNP
rs1018724506 943 dbSNP
rs1347974191 944 dbSNP
rs563825725 944 dbSNP
rs777130382 948 dbSNP
rs1286457966 949 dbSNP
rs1298397013 951 dbSNP
rs762325393 952 dbSNP
rs975045368 953 dbSNP
rs868637954 954 dbSNP
rs920614165 956 dbSNP
rs1395742309 959 dbSNP
rs1429715895 959 dbSNP
rs1175545965 963 dbSNP
rs1210115581 965 dbSNP
rs958292342 968 dbSNP
rs950709927 973 dbSNP
rs1446871896 977 dbSNP
rs866143113 978 dbSNP
rs913988860 979 dbSNP
rs1378054445 980 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' acuugacgGACAGAGGAAGGAc 5'
                  || |  ||||||| 
Target 5' ---auacaCUUUGGCCUUCCUu 3'
 		1 - 19
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000301019.4 | 3UTR | AUACACUUUGGCCUUCCUUUCCCCA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
152 hsa-miR-6876-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT065634 CLIC4 chloride intracellular channel 4 2 2
MIRT076193 GID4 GID complex subunit 4 homolog 2 4
MIRT086307 HOXD8 homeobox D8 2 6
MIRT110648 ARID5B AT-rich interaction domain 5B 2 2
MIRT144349 NFAT5 nuclear factor of activated T-cells 5 2 2
MIRT196639 TAOK1 TAO kinase 1 2 6
MIRT227659 SET SET nuclear proto-oncogene 2 2
MIRT263554 PPIF peptidylprolyl isomerase F 2 4
MIRT266192 TXNIP thioredoxin interacting protein 2 4
MIRT266824 SLC25A44 solute carrier family 25 member 44 2 2
MIRT285546 CDT1 chromatin licensing and DNA replication factor 1 2 2
MIRT295099 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT300914 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT304115 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 6
MIRT314893 RGMB repulsive guidance molecule family member b 2 2
MIRT364227 ANP32B acidic nuclear phosphoprotein 32 family member B 2 2
MIRT366244 VMA21 VMA21, vacuolar ATPase assembly factor 2 2
MIRT405447 RAB5B RAB5B, member RAS oncogene family 2 2
MIRT443612 OR2D2 olfactory receptor family 2 subfamily D member 2 2 2
MIRT445946 SCML4 Scm polycomb group protein like 4 2 2
MIRT445956 MLLT11 MLLT11, transcription factor 7 cofactor 2 2
MIRT445968 IKZF5 IKAROS family zinc finger 5 2 2
MIRT448064 MMP15 matrix metallopeptidase 15 2 2
MIRT449497 ZBTB4 zinc finger and BTB domain containing 4 2 2
MIRT450830 IFFO1 intermediate filament family orphan 1 2 2
MIRT451269 NDUFA11 NADH:ubiquinone oxidoreductase subunit A11 2 2
MIRT451317 LGALS3BP galectin 3 binding protein 2 2
MIRT451402 FARSA phenylalanyl-tRNA synthetase alpha subunit 2 2
MIRT451940 TMPRSS5 transmembrane protease, serine 5 2 2
MIRT452029 NLRP6 NLR family pyrin domain containing 6 2 2
MIRT452502 HMGXB3 HMG-box containing 3 2 2
MIRT453851 SDK1 sidekick cell adhesion molecule 1 2 2
MIRT454521 ZFYVE27 zinc finger FYVE-type containing 27 2 2
MIRT455401 PLA2G2F phospholipase A2 group IIF 2 2
MIRT455441 ID3 inhibitor of DNA binding 3, HLH protein 2 2
MIRT456982 MANEA mannosidase endo-alpha 2 2
MIRT457609 IDS iduronate 2-sulfatase 2 2
MIRT458318 TNFAIP8L3 TNF alpha induced protein 8 like 3 2 2
MIRT458755 CES2 carboxylesterase 2 2 2
MIRT458958 SAMD4B sterile alpha motif domain containing 4B 2 2
MIRT460402 GPHA2 glycoprotein hormone alpha 2 2 2
MIRT460631 IGFBP4 insulin like growth factor binding protein 4 2 2
MIRT461759 DDX11 DEAD/H-box helicase 11 2 2
MIRT461923 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT461976 PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2 2
MIRT462270 TPI1 triosephosphate isomerase 1 2 2
MIRT462303 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT462724 SEMA4G semaphorin 4G 2 2
MIRT463413 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463524 ZBTB7B zinc finger and BTB domain containing 7B 2 2
MIRT464087 VPS4A vacuolar protein sorting 4 homolog A 2 2
MIRT464621 UBE4B ubiquitination factor E4B 2 2
MIRT465029 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT465561 TOB2 transducer of ERBB2, 2 2 2
MIRT465889 TMEM43 transmembrane protein 43 2 2
MIRT466426 TFAP2A transcription factor AP-2 alpha 2 8
MIRT466592 TBC1D2B TBC1 domain family member 2B 2 2
MIRT467622 SLC7A5 solute carrier family 7 member 5 2 2
MIRT468510 SESN2 sestrin 2 2 2
MIRT468648 SEH1L SEH1 like nucleoporin 2 2
MIRT468736 SDC4 syndecan 4 2 2
MIRT468751 SDC2 syndecan 2 2 2
MIRT469181 RNF111 ring finger protein 111 2 2
MIRT469475 REEP5 receptor accessory protein 5 2 2
MIRT472077 NOVA2 NOVA alternative splicing regulator 2 2 2
MIRT472092 NOLC1 nucleolar and coiled-body phosphoprotein 1 2 2
MIRT472193 NHP2L1 small nuclear ribonucleoprotein 13 2 2
MIRT472451 NAV2 neuron navigator 2 2 6
MIRT474491 KLHDC8B kelch domain containing 8B 2 2
MIRT475173 IP6K1 inositol hexakisphosphate kinase 1 2 2
MIRT475349 IFNLR1 interferon lambda receptor 1 2 2
MIRT476472 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT477093 FAM168A family with sequence similarity 168 member A 2 2
MIRT477178 F3 coagulation factor III, tissue factor 2 6
MIRT478025 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT479586 CDC42SE1 CDC42 small effector 1 2 2
MIRT480116 CALR calreticulin 2 2
MIRT480464 C11orf84 chromosome 11 open reading frame 84 2 2
MIRT480802 BLOC1S2 biogenesis of lysosomal organelles complex 1 subunit 2 2 6
MIRT481075 B4GALT1 beta-1,4-galactosyltransferase 1 2 2
MIRT482574 ABHD2 abhydrolase domain containing 2 2 2
MIRT482689 NXN nucleoredoxin 2 4
MIRT483598 SLC26A9 solute carrier family 26 member 9 2 2
MIRT485010 TNRC6B trinucleotide repeat containing 6B 2 4
MIRT488050 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 2
MIRT488066 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 2
MIRT488175 PRRC2B proline rich coiled-coil 2B 2 4
MIRT488858 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT489073 STARD3 StAR related lipid transfer domain containing 3 2 2
MIRT489180 ANKRD45 ankyrin repeat domain 45 2 2
MIRT489979 DDB1 damage specific DNA binding protein 1 2 2
MIRT490226 WRN Werner syndrome RecQ like helicase 2 2
MIRT491082 HILPDA hypoxia inducible lipid droplet associated 2 2
MIRT491541 HDAC5 histone deacetylase 5 2 2
MIRT492539 PSMD11 proteasome 26S subunit, non-ATPase 11 2 2
MIRT499032 MAG myelin associated glycoprotein 2 2
MIRT499419 PLCG2 phospholipase C gamma 2 2 4
MIRT499819 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT500045 SDE2 SDE2 telomere maintenance homolog 2 6
MIRT500843 SYPL1 synaptophysin like 1 2 4
MIRT504517 PPP1R9B protein phosphatase 1 regulatory subunit 9B 2 2
MIRT505621 SLC25A37 solute carrier family 25 member 37 2 2
MIRT509135 STK4 serine/threonine kinase 4 2 2
MIRT509218 BUB3 BUB3, mitotic checkpoint protein 2 4
MIRT510751 SLC7A1 solute carrier family 7 member 1 2 2
MIRT512114 CREBZF CREB/ATF bZIP transcription factor 2 2
MIRT512316 ACTR2 ARP2 actin related protein 2 homolog 2 6
MIRT517394 BGN biglycan 2 4
MIRT518411 SSU72 SSU72 homolog, RNA polymerase II CTD phosphatase 2 4
MIRT521361 RPL35A ribosomal protein L35a 2 2
MIRT525071 FRK fyn related Src family tyrosine kinase 2 2
MIRT525799 SOD2 superoxide dismutase 2 2 2
MIRT530429 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT541466 AURKA aurora kinase A 2 2
MIRT544302 TSPYL1 TSPY like 1 2 2
MIRT546414 SPRED3 sprouty related EVH1 domain containing 3 2 2
MIRT546581 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT548763 CNN3 calponin 3 2 2
MIRT549808 KIAA0391 KIAA0391 2 2
MIRT550612 MTHFR methylenetetrahydrofolate reductase 2 2
MIRT552226 FIG4 FIG4 phosphoinositide 5-phosphatase 2 4
MIRT554007 SPTLC1 serine palmitoyltransferase long chain base subunit 1 2 2
MIRT554115 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT555099 PURB purine rich element binding protein B 2 2
MIRT560289 HRH2 histamine receptor H2 2 2
MIRT560382 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT560799 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT560979 IWS1 IWS1, SUPT6H interacting protein 2 2
MIRT561160 BCL2L12 BCL2 like 12 2 2
MIRT562388 EN2 engrailed homeobox 2 2 2
MIRT562481 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT567783 DGAT2 diacylglycerol O-acyltransferase 2 2 2
MIRT568830 TRIM67 tripartite motif containing 67 2 2
MIRT569554 UNC119B unc-119 lipid binding chaperone B 2 2
MIRT572381 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT575791 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b 2 2
MIRT610504 CTBS chitobiase 2 4
MIRT616604 PAPD5 poly(A) RNA polymerase D5, non-canonical 2 2
MIRT621779 TMEM87B transmembrane protein 87B 2 2
MIRT634216 TMEM192 transmembrane protein 192 2 2
MIRT639650 WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules 2 2
MIRT642498 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT643216 TYW3 tRNA-yW synthesizing protein 3 homolog 2 4
MIRT674821 KCNJ10 potassium voltage-gated channel subfamily J member 10 2 2
MIRT697355 ZNF426 zinc finger protein 426 2 2
MIRT704674 CHTOP chromatin target of PRMT1 2 2
MIRT708703 TFDP2 transcription factor Dp-2 2 2
MIRT709659 DFFB DNA fragmentation factor subunit beta 2 2
MIRT711279 SDR9C7 short chain dehydrogenase/reductase family 9C member 7 2 2
MIRT713732 SUCO SUN domain containing ossification factor 2 2
MIRT715005 TSPAN11 tetraspanin 11 2 2
MIRT718399 ALDH1A3 aldehyde dehydrogenase 1 family member A3 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-6876 Paclitaxel 36314 NSC125973 approved sensitive cell line (HS578T)
hsa-miR-6876-5p Docetaxel 148124 NSC628503 approved resistant High Breast Cancer cell line (MDA-MB-231, MCF-7)
hsa-miR-6876-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-6876-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-6876-5p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-6876-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)

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