miRTarBase - #MIRT292954


—
pre-miRNA Information
pre-miRNA hsa-mir-3915   
Genomic Coordinates chrX: 32583656 - 32583752
Description Homo sapiens miR-3915 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3915
Sequence 21| UUGAGGAAAAGAUGGUCUUAUU |42
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs997323565 10 dbSNP
rs1192161547 15 dbSNP
rs1255075246 19 dbSNP
rs1452812574 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ZNF146   
Synonyms OZF
Description zinc finger protein 146
Transcript NM_001099638   
Other Transcripts NM_001099639 , NM_007145   
Expression
Putative miRNA Targets on ZNF146
3'UTR of ZNF146
(miRNA target sites are highlighted)		 
>ZNF146|NM_001099638|3'UTR
   1 AAACCCCATGAAAGCCTTGAAAGTGGGAAAGCTTTCATTAGAAATTTGCACCTCATCATGCCCCAGAAATAATCCTTCTG
  81 AAGCAAAGCACCACGAATGAGGTTAACTTTAACAAGTACTAAAAACTTAAGGGACACCAGAAAATTTGTACTGAAGAGAA
 161 AGACATGCATATGATTAAAACCCTGTGTCCAACAGAGAAACCTGCAGCAGAGATAATGGTGAAAGTTTAGGCACATTTTC
 241 ACTAAAAGTGGGAACAGAAAATGGAGGCCTGTTTTTTATTGCTACCACCATAGATCTGGAGATCTTCGCCAGTAACAAGA
 321 AAAATTAAGTTGTAAATATTGGAAAGGAACAGACAAAAATAGATGACATGGTCATCTACAACTAATATTAAGACTCCTGT
 401 GGTATTGATTGAGCAGAGCAGAAGAGATTTCAAAAAAAGACCTATGCATTTATTAGAATTTGGAATATGATACAAGTGGC
 481 ATCAGGAAATGAGGAAATAATGGAACTATTTTTTTTAAGTGGAGGTAGTTTGTTCTCCAAGGGGGAAAAATAGACCATGA
 561 ACTATACACAAAAGTGAATCCAGAGATTAAAAACAGAAATATGGAAAAGCTATGTACTAAAATGCATATGACCTTGGGAA
 641 TAGGGAAACATTCCTTGGAACAATTTGAGAAATACTTAGCGGTTCTACTTATGAGTATGAATGCTCAGGAAATACGCACT
 721 AGGATATTTACTGTGGCTTGATTTGTAGTAGCCAAAAATTAGAAACAACTGAGAAAGCCCATCACGAACAATATGGGAAA
 801 TTCTTATGTAATACTATATATCTGTAAAATGCAACAAATGAAATCCACATGTATTAACAGAAAGATCCCAGAATTGTTGA
 881 GGGGGGATCAAGTTGCAGAATGATACAGATAGTACAATGACTTTTTTGTAAATTTGAATTAAAAGTTTCCTCATAAAACT
 961 CAGTACTATCTATTGGTAATGGATGCATATATGTATGTACATGTTTTTGAAACGGATTGGAAGGATACAGACCAAACTCT
1041 TGATAGTGGTCACCTGTGAAGAGTGGAGAAGGGAAAATAATGAGTGTGGGAGGTGGGATGGGTATTGGTTAAAGGGGACT
1121 TCAGCTTTTTATATAAACATCCACTTCTCTTTCAAAAGACTTCAAGTAAATATAAGAAGATACTGATTGATTCTGGATTG
1201 TGGTATAGGGATATCTTGTCTTATTTTTTGTACTTTTCTGTATTTTTAAAATTTCTCAAAATAGGAATGGGAGTGAGGAT
1281 GGGAATGCTGTATCTGTGGAAGTCATGTTATACTGGATTCATTTCCAATTAAATACTAAACATTTTATAGAAAATATTTC
1361 TAAAATTTTATCACGGATGAATGGATGGACTTGCTCTCTATGTAATATGAAATTAATCTATTTTATTAAAATTTAAAAGG
1441 ACAGCACAATCCAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uuauucugguagaAAAGGAGUu 5'
                       |||||||| 
Target 5' tttgaattaaaagTTTCCTCAt 3'
 933 - 954 145.00 -8.80
2 
miRNA  3' uuauucugGUAGAA-----AAGGAGUu 5'
                  :||:||     ||:|||| 
Target 5' cttttctgTATTTTTAAAATTTCTCAa 3'
 1233 - 1259 130.00 -7.10
3 
miRNA  3' uuAUU--CUGGUAGAAAAGGAGUu 5'
            |||  || | | ||||::|:| 
Target 5' aaTAATGGAAC-TATTTTTTTTAa 3'
 496 - 518 113.00 -9.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM6828111 4 COSMIC
COSN30113709 42 COSMIC
COSN30145346 44 COSMIC
COSN30185211 65 COSMIC
COSN18742348 70 COSMIC
COSN30106804 71 COSMIC
COSN20115763 78 COSMIC
COSN30133665 95 COSMIC
COSN30120874 96 COSMIC
COSN19704451 99 COSMIC
COSN5760221 182 COSMIC
COSN30136255 198 COSMIC
COSN30534164 293 COSMIC
COSN30117479 309 COSMIC
COSN31485805 427 COSMIC
COSN30142037 456 COSMIC
COSN31520895 586 COSMIC
COSN31579365 634 COSMIC
COSN31521152 670 COSMIC
COSN30511149 758 COSMIC
COSN31593571 761 COSMIC
COSN24294797 887 COSMIC
COSN30534269 931 COSMIC
COSN15627046 953 COSMIC
COSN30114823 969 COSMIC
COSN15934429 1040 COSMIC
COSN30509923 1144 COSMIC
COSN31584558 1177 COSMIC
COSN31548085 1251 COSMIC
COSN26549073 1266 COSMIC
COSN31589398 1376 COSMIC
COSN30172113 1397 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs201354591 6 dbSNP
rs1347964032 7 dbSNP
rs1199011588 8 dbSNP
rs1031571698 12 dbSNP
rs1263463228 21 dbSNP
rs758158163 23 dbSNP
rs1000108253 24 dbSNP
rs777456406 27 dbSNP
rs545019888 31 dbSNP
rs757232347 33 dbSNP
rs202080948 35 dbSNP
rs958428927 37 dbSNP
rs780646793 38 dbSNP
rs769421161 44 dbSNP
rs1177269352 48 dbSNP
rs1348566737 50 dbSNP
rs1426928784 52 dbSNP
rs1409663289 53 dbSNP
rs184364400 55 dbSNP
rs1011526296 56 dbSNP
rs1470465956 59 dbSNP
rs991534309 61 dbSNP
rs1185106261 63 dbSNP
rs4806293 70 dbSNP
rs200453092 75 dbSNP
rs1267871935 86 dbSNP
rs773496838 91 dbSNP
rs986938292 96 dbSNP
rs912694113 101 dbSNP
rs1195686139 111 dbSNP
rs1228372088 112 dbSNP
rs1351987433 114 dbSNP
rs1428622229 122 dbSNP
rs1373565187 123 dbSNP
rs961669043 127 dbSNP
rs1337553988 135 dbSNP
rs1454773731 138 dbSNP
rs761066998 142 dbSNP
rs866148644 144 dbSNP
rs971798957 150 dbSNP
rs1319950580 154 dbSNP
rs1167381759 165 dbSNP
rs1394470892 167 dbSNP
rs918797956 168 dbSNP
rs549052120 170 dbSNP
rs771379283 172 dbSNP
rs1161267504 177 dbSNP
rs1432496291 182 dbSNP
rs930107797 183 dbSNP
rs1426740760 190 dbSNP
rs1304004597 193 dbSNP
rs984399256 198 dbSNP
rs1345207931 201 dbSNP
rs1185123044 203 dbSNP
rs910094233 208 dbSNP
rs767787488 213 dbSNP
rs1463250911 216 dbSNP
rs942736905 218 dbSNP
rs1246924060 223 dbSNP
rs1208762225 224 dbSNP
rs1040072310 226 dbSNP
rs922720199 227 dbSNP
rs1356167402 229 dbSNP
rs1298275577 235 dbSNP
rs920181788 236 dbSNP
rs1327519707 239 dbSNP
rs1248511675 256 dbSNP
rs930334981 266 dbSNP
rs759953248 269 dbSNP
rs1227406912 271 dbSNP
rs1431511908 272 dbSNP
rs1048719482 284 dbSNP
rs934113614 286 dbSNP
rs948421394 291 dbSNP
rs1366012867 297 dbSNP
rs1165204058 298 dbSNP
rs1447315554 299 dbSNP
rs1249083622 308 dbSNP
rs1041781880 309 dbSNP
rs1244467659 317 dbSNP
rs1220076816 326 dbSNP
rs1490324347 330 dbSNP
rs1293014404 363 dbSNP
rs578191476 364 dbSNP
rs1361016207 369 dbSNP
rs1297070424 373 dbSNP
rs1215247976 375 dbSNP
rs1273140398 376 dbSNP
rs1222715036 378 dbSNP
rs907052646 382 dbSNP
rs903048765 389 dbSNP
rs1427516633 395 dbSNP
rs1290602098 398 dbSNP
rs1170786914 399 dbSNP
rs1411280124 403 dbSNP
rs1422511526 405 dbSNP
rs1190096266 410 dbSNP
rs1480416055 411 dbSNP
rs1489756699 420 dbSNP
rs1202061424 427 dbSNP
rs999972919 430 dbSNP
rs1054393355 432 dbSNP
rs1251101762 432 dbSNP
rs373250152 440 dbSNP
rs531574231 442 dbSNP
rs1324201286 443 dbSNP
rs1012591849 445 dbSNP
rs1190972760 453 dbSNP
rs1388346262 461 dbSNP
rs1407912996 465 dbSNP
rs1011537495 470 dbSNP
rs1028246657 474 dbSNP
rs1159865505 484 dbSNP
rs11545134 485 dbSNP
rs1164376398 491 dbSNP
rs549708494 494 dbSNP
rs1024424488 495 dbSNP
rs1423040560 507 dbSNP
rs1290977765 509 dbSNP
rs1386184020 523 dbSNP
rs971048760 526 dbSNP
rs1174775071 529 dbSNP
rs993267309 536 dbSNP
rs1019677305 539 dbSNP
rs961877701 541 dbSNP
rs1471889346 542 dbSNP
rs1360687414 552 dbSNP
rs1178099683 555 dbSNP
rs775299666 563 dbSNP
rs1026053548 565 dbSNP
rs762633256 567 dbSNP
rs1203117848 568 dbSNP
rs1324440886 570 dbSNP
rs763705833 571 dbSNP
rs1226544355 581 dbSNP
rs1246085797 586 dbSNP
rs1313808224 595 dbSNP
rs972922612 600 dbSNP
rs1356791071 610 dbSNP
rs984263544 613 dbSNP
rs751079843 616 dbSNP
rs1301832232 617 dbSNP
rs964611613 618 dbSNP
rs1485433353 625 dbSNP
rs867956779 626 dbSNP
rs984467631 627 dbSNP
rs761717482 633 dbSNP
rs1461766716 639 dbSNP
rs571547721 665 dbSNP
rs933974584 680 dbSNP
rs538542124 681 dbSNP
rs767470903 682 dbSNP
rs189514136 693 dbSNP
rs144203288 695 dbSNP
rs924671150 704 dbSNP
rs775966218 710 dbSNP
rs1401131776 716 dbSNP
rs750226785 717 dbSNP
rs1485518364 718 dbSNP
rs1364693637 720 dbSNP
rs1261184523 725 dbSNP
rs565711273 726 dbSNP
rs894300866 727 dbSNP
rs1287567154 730 dbSNP
rs1408917879 732 dbSNP
rs536352720 733 dbSNP
rs755936980 735 dbSNP
rs1246323663 749 dbSNP
rs906894790 754 dbSNP
rs893064440 759 dbSNP
rs993133315 760 dbSNP
rs554605037 763 dbSNP
rs1384877821 766 dbSNP
rs1290039391 767 dbSNP
rs1455789570 774 dbSNP
rs1379977824 779 dbSNP
rs576452010 782 dbSNP
rs1026086245 786 dbSNP
rs112406709 787 dbSNP
rs1316047414 795 dbSNP
rs1005728951 808 dbSNP
rs563900565 817 dbSNP
rs75206820 821 dbSNP
rs897197590 823 dbSNP
rs577478579 826 dbSNP
rs976094156 831 dbSNP
rs1206888340 847 dbSNP
rs1487453596 850 dbSNP
rs1482332426 852 dbSNP
rs994751259 854 dbSNP
rs1027125246 881 dbSNP
rs952957684 882 dbSNP
rs1418791640 885 dbSNP
rs1271957849 886 dbSNP
rs922845360 887 dbSNP
rs1297063191 902 dbSNP
rs1384457873 907 dbSNP
rs991090978 908 dbSNP
rs955388834 910 dbSNP
rs1431949792 916 dbSNP
rs1302951280 922 dbSNP
rs1470565270 922 dbSNP
rs1023877708 923 dbSNP
rs1425629671 926 dbSNP
rs779020477 942 dbSNP
rs969747643 951 dbSNP
rs541334023 954 dbSNP
rs748237175 960 dbSNP
rs1356874591 961 dbSNP
rs924706001 964 dbSNP
rs1195380370 969 dbSNP
rs560192962 971 dbSNP
rs1268020798 973 dbSNP
rs1298318490 976 dbSNP
rs1372142404 977 dbSNP
rs1389367692 978 dbSNP
rs1249330910 980 dbSNP
rs934395019 982 dbSNP
rs1339618084 986 dbSNP
rs1372071566 988 dbSNP
rs1324043001 995 dbSNP
rs140084837 1002 dbSNP
rs1322054873 1010 dbSNP
rs1406090250 1014 dbSNP
rs778371576 1014 dbSNP
rs948566204 1015 dbSNP
rs1327243225 1024 dbSNP
rs1391081599 1025 dbSNP
rs1397431583 1027 dbSNP
rs527471444 1029 dbSNP
rs1169736125 1037 dbSNP
rs1046071204 1041 dbSNP
rs1428677489 1051 dbSNP
rs1310452293 1053 dbSNP
rs1177138901 1058 dbSNP
rs907094489 1062 dbSNP
rs1049662168 1063 dbSNP
rs576047337 1064 dbSNP
rs1480410029 1066 dbSNP
rs1445381414 1069 dbSNP
rs1047396177 1080 dbSNP
rs887435679 1081 dbSNP
rs1252160154 1083 dbSNP
rs1006424770 1085 dbSNP
rs1480974903 1087 dbSNP
rs747422958 1092 dbSNP
rs897242357 1100 dbSNP
rs1460544786 1102 dbSNP
rs1263207999 1104 dbSNP
rs994239263 1107 dbSNP
rs1232450926 1119 dbSNP
rs1412187141 1121 dbSNP
rs1027050336 1122 dbSNP
rs900028971 1123 dbSNP
rs996996934 1125 dbSNP
rs1331204898 1132 dbSNP
rs771432411 1134 dbSNP
rs1405502716 1135 dbSNP
rs542634898 1136 dbSNP
rs1427381125 1141 dbSNP
rs1012415333 1146 dbSNP
rs1157793274 1152 dbSNP
rs181826440 1154 dbSNP
rs1470353587 1155 dbSNP
rs1304608327 1156 dbSNP
rs955583917 1166 dbSNP
rs143357331 1174 dbSNP
rs1185040510 1175 dbSNP
rs1404117929 1180 dbSNP
rs1443609788 1181 dbSNP
rs1281222270 1184 dbSNP
rs1031671891 1193 dbSNP
rs957374752 1202 dbSNP
rs549983382 1206 dbSNP
rs767213189 1212 dbSNP
rs1205053524 1214 dbSNP
rs956002109 1214 dbSNP
rs1351921623 1224 dbSNP
rs1281614730 1248 dbSNP
rs988544011 1263 dbSNP
rs185458726 1264 dbSNP
rs1315845567 1271 dbSNP
rs1454591966 1271 dbSNP
rs968561757 1272 dbSNP
rs948575920 1273 dbSNP
rs1317639147 1276 dbSNP
rs1307013780 1291 dbSNP
rs1401208146 1291 dbSNP
rs1386934827 1299 dbSNP
rs1161408498 1303 dbSNP
rs1203211506 1305 dbSNP
rs981257017 1308 dbSNP
rs1184918192 1312 dbSNP
rs1474178113 1313 dbSNP
rs911144143 1329 dbSNP
rs1448050047 1330 dbSNP
rs189584048 1334 dbSNP
rs1359009822 1342 dbSNP
rs1490593814 1342 dbSNP
rs1292686841 1343 dbSNP
rs929243635 1348 dbSNP
rs1047677444 1350 dbSNP
rs1222197981 1353 dbSNP
rs1269653379 1356 dbSNP
rs1431443574 1362 dbSNP
rs867308650 1363 dbSNP
rs1041460314 1368 dbSNP
rs1423702267 1375 dbSNP
rs941692522 1376 dbSNP
rs1165146210 1390 dbSNP
rs775263019 1393 dbSNP
rs1418217248 1394 dbSNP
rs761151948 1398 dbSNP
rs1167945610 1399 dbSNP
rs1187649284 1401 dbSNP
rs547245191 1402 dbSNP
rs1048542325 1415 dbSNP
rs1197717853 1419 dbSNP
rs1447150086 1422 dbSNP
rs1490308658 1431 dbSNP
rs900226734 1438 dbSNP
rs888532390 1447 dbSNP
rs1224123341 1450 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uuauucugguagaAAAGGAGUu 5'
                       |||||||| 
Target 5' ----aauuaaaagUUUCCUCAu 3'
 		1 - 18
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 7705.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM545212
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / Control
Location of target site ENST00000443387.2 | 3UTR | UCCUCAUAAAACUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000443387.2 | 3UTR | AAUUAAAAGUUUCCUCAUAAAACUCAGUACUAUCUAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000443387.2 | 3UTR | AAUUAAAAGUUUCCUCAUAAAACUCAGUACUAUCUAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
111 hsa-miR-3915 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059544 PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha 2 2
MIRT081703 ZNF507 zinc finger protein 507 2 2
MIRT083311 ZCCHC3 zinc finger CCHC-type containing 3 2 6
MIRT119046 SFT2D3 SFT2 domain containing 3 2 2
MIRT189381 TXLNA taxilin alpha 2 4
MIRT195895 C16ORF72 chromosome 16 open reading frame 72 2 6
MIRT223807 OXR1 oxidation resistance 1 2 2
MIRT292954 ZNF146 zinc finger protein 146 2 4
MIRT293949 RPL13A ribosomal protein L13a 2 6
MIRT300900 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT339332 SESN2 sestrin 2 2 2
MIRT349304 ZNF317 zinc finger protein 317 2 2
MIRT364736 TOR1B torsin family 1 member B 2 2
MIRT366233 VMA21 VMA21, vacuolar ATPase assembly factor 2 2
MIRT384605 CLIC4 chloride intracellular channel 4 2 2
MIRT401745 HLA-DRA major histocompatibility complex, class II, DR alpha 2 2
MIRT443169 UBL3 ubiquitin like 3 2 2
MIRT444215 METTL12 methyltransferase like 12 2 2
MIRT444375 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT445340 TCEANC transcription elongation factor A N-terminal and central domain containing 2 2
MIRT445474 KDM6A lysine demethylase 6A 2 2
MIRT445598 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT445630 TMEM50A transmembrane protein 50A 2 2
MIRT446012 VNN1 vanin 1 2 2
MIRT446115 ASTN1 astrotactin 1 2 2
MIRT446248 ELP2 elongator acetyltransferase complex subunit 2 2 2
MIRT446382 SYNCRIP synaptotagmin binding cytoplasmic RNA interacting protein 2 2
MIRT446940 ZMAT3 zinc finger matrin-type 3 2 2
MIRT446967 SLCO4C1 solute carrier organic anion transporter family member 4C1 2 2
MIRT447178 PGRMC2 progesterone receptor membrane component 2 2 2
MIRT447209 APBB2 amyloid beta precursor protein binding family B member 2 2 2
MIRT447237 IHH indian hedgehog 2 2
MIRT447807 EMX1 empty spiracles homeobox 1 2 2
MIRT447853 RRP8 ribosomal RNA processing 8 2 4
MIRT448054 MMP15 matrix metallopeptidase 15 2 2
MIRT448094 RASD2 RASD family member 2 2 2
MIRT448704 KLHL11 kelch like family member 11 2 2
MIRT448851 FEM1C fem-1 homolog C 2 2
MIRT449488 ZBTB4 zinc finger and BTB domain containing 4 2 2
MIRT449785 C1orf109 chromosome 1 open reading frame 109 2 2
MIRT450774 PDE3A phosphodiesterase 3A 2 2
MIRT451124 ZNF99 zinc finger protein 99 2 2
MIRT452676 GPR156 G protein-coupled receptor 156 2 2
MIRT452888 PSD4 pleckstrin and Sec7 domain containing 4 2 2
MIRT453188 ACSF2 acyl-CoA synthetase family member 2 2 2
MIRT453353 ZNF3 zinc finger protein 3 2 2
MIRT454502 ZFYVE27 zinc finger FYVE-type containing 27 2 2
MIRT454629 FAM83H family with sequence similarity 83 member H 2 2
MIRT455183 AGTRAP angiotensin II receptor associated protein 2 2
MIRT458204 FOXL2 forkhead box L2 2 2
MIRT458723 CES2 carboxylesterase 2 2 2
MIRT458942 SAMD4B sterile alpha motif domain containing 4B 2 2
MIRT460304 FLCN folliculin 2 2
MIRT460989 SYT7 synaptotagmin 7 2 2
MIRT461697 ZNF426 zinc finger protein 426 2 2
MIRT461903 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462193 NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 2 2
MIRT462290 PPM1H protein phosphatase, Mg2+/Mn2+ dependent 1H 2 2
MIRT463795 XPOT exportin for tRNA 2 2
MIRT464649 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 4
MIRT465911 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 4
MIRT465992 TMEM189 transmembrane protein 189 2 4
MIRT466302 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT466575 TBC1D2B TBC1 domain family member 2B 2 2
MIRT470558 POU2F1 POU class 2 homeobox 1 2 2
MIRT471333 PERP PERP, TP53 apoptosis effector 2 2
MIRT471659 PALM2 paralemmin 2 2 2
MIRT472363 TSPAN1 tetraspanin 1 2 2
MIRT473468 MCFD2 multiple coagulation factor deficiency 2 2 2
MIRT474702 KIF3A kinesin family member 3A 2 2
MIRT476067 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT476077 GRB2 growth factor receptor bound protein 2 2 2
MIRT476423 GBA2 glucosylceramidase beta 2 2 2
MIRT476463 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT477877 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT478240 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT479460 CDK6 cyclin dependent kinase 6 2 2
MIRT481030 BAZ2A bromodomain adjacent to zinc finger domain 2A 2 2
MIRT491496 HLA-DOA major histocompatibility complex, class II, DO alpha 2 2
MIRT497585 SLC23A1 solute carrier family 23 member 1 2 2
MIRT498542 TMEM30B transmembrane protein 30B 2 2
MIRT499263 NBPF11 NBPF member 11 2 2
MIRT504698 ZNF117 zinc finger protein 117 2 2
MIRT511288 KLHL15 kelch like family member 15 2 4
MIRT523121 HSP90B1 heat shock protein 90 beta family member 1 2 4
MIRT529601 H1F0 H1 histone family member 0 2 2
MIRT533481 TRIM71 tripartite motif containing 71 2 2
MIRT535571 NUP37 nucleoporin 37 2 4
MIRT537869 EDA2R ectodysplasin A2 receptor 2 2
MIRT538010 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552681 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 4
MIRT554986 RAB39B RAB39B, member RAS oncogene family 2 2
MIRT556659 KMT2D lysine methyltransferase 2D 2 4
MIRT557437 GTPBP2 GTP binding protein 2 2 2
MIRT560813 CRTAP cartilage associated protein 2 2
MIRT562115 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT563103 IFRD2 interferon related developmental regulator 2 2 2
MIRT574199 LMNB1 lamin B1 2 2
MIRT623920 FMNL3 formin like 3 2 2
MIRT626551 NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2 2
MIRT645458 ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 2 2
MIRT649082 CACNA1B calcium voltage-gated channel subunit alpha1 B 2 2
MIRT659477 CLDN1 claudin 1 2 2
MIRT667950 HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 2 2
MIRT701981 MIER3 MIER family member 3 2 2
MIRT708694 TFDP2 transcription factor Dp-2 2 2
MIRT709649 DFFB DNA fragmentation factor subunit beta 2 2
MIRT710090 FAM229B family with sequence similarity 229 member B 2 2
MIRT718396 ALDH1A3 aldehyde dehydrogenase 1 family member A3 2 2
MIRT724972 TNS1 tensin 1 2 2
MIRT756050 HRH4 histamine receptor H4 2 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3915 Paclitaxel 36314 NSC125973 approved resistant High Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-3915 Cisplatin + Decitabine sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-mir-3915 Cisplatin 5460033 NSC119875 approved sensitive cell line (BxPC3)
hsa-miR-3915 Tripterygium wilfordii Hook F sensitive tissue
hsa-miR-3915 Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-3915 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3915 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

Error report submission