miRTarBase - #MIRT301381


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pre-miRNA Information
pre-miRNA hsa-mir-4662a   
Genomic Coordinates chr8: 124821985 - 124822051
Description Homo sapiens miR-4662a stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4662a-5p
Sequence 6| UUAGCCAAUUGUCCAUCUUUAG |27
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 3 8 + 124821992 27229138, 28550310, 29165639, 29233923 MiREDiBase
A-to-I 15 8 + 124822004 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs193002095 8 dbSNP
rs1020047688 11 dbSNP
rs1051104297 12 dbSNP
rs577795897 15 dbSNP
rs1347413245 16 dbSNP
Putative Targets

Gene Information
Gene Symbol PDXP   
Synonyms CIN, PLP, dJ37E16.5
Description pyridoxal phosphatase
Transcript NM_020315   
Expression
Putative miRNA Targets on PDXP
3'UTR of PDXP
(miRNA target sites are highlighted)		 
>PDXP|NM_020315|3'UTR
   1 GCCCACTGCACCTGCAGCCACAGGCCCACCCCTCCCCACTCCCTGATCCCGTAGGTGGAGGCGATGGGTCACGAGCCATG
  81 TTAAGCACAACCGGCTCCTTGGTCCAGTTCTGCACCGGGGTGGGGCTGGGACCCGGGGAAGGTTTGAGGGCCCTTGCAAC
 161 CCCCTCCCAGCAGTGGCTGGGCACTCTTTGCTGCCCCAGAAGCTGGTCCCCTATGGATTCATCTTGGCCTGACCCAGCCA
 241 GGTGGCCTTATTTCTTCCCTGTCACCTCCCCTCCTTGAAATCTGGGCCCTGGTGCCTGCTGAAGATTCCCTCTATCCCTG
 321 AGTACTTAGTCTTCTCCCCCTTCCCTGGGGCTTCTAGAGCTCTCTCTGCCCCTCAGGTCCTGGCCCTTGGGTCCTTGTCA
 401 ACCAGAGGTCTAGGGAACCACAACCCTTATTGTCCTGGGTGGACCAATCCAAAGGCTAAGTGATAGTGACTCATCAATGT
 481 TGGGTCCTGTGGGGTACCAGTTTAGGTTCCTAAGTAATAGTGACCCTTTCACGTCCTGGAGCCCGAGTGGACCAATCGGA
 561 AGCCTAAGTGACGATGACCCTCGCATGTCCTAGGTCCCTGGGTGGACCCATCAGGACCCCAAGTGATAGTGACCCAGTGG
 641 TCTTTTAGATCCTCAGTAGAACAGTCCAGAAGCCTGAGAGACAGTGGCCCCTTGATAATCTGGGTCTCACGGGACCAGCT
 721 AGGGGTCCAGGTTTCAGTCAGTAAATAAGAGTGGTCCACGTCCTAAAGACACCTCTCCTTTACAAAGACTTGTGATGCTC
 801 TGGGGCTTCTGTGGCCAAGCCCCACCCTTTCCTGGTCATGGTACCCGTACAGCGTTGATGGCCACAGCTCGAAGGGGGGC
 881 TTTCGTGTCCCCCTGTGCGGTCAGTGTTTTCAGTACCACCTCTCTCCCGTGCCCACTTGGCTATTTACTTATTTATTTAT
 961 TGTGTGCCAGTGATGGTGGGTGGGGGCTGGGCCTTCCCCGCCACCTCCACCCCTGTTGTGACCTGTCCTTCCGTACTTAA
1041 TAAAGTGCGCGTGGGAGTGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
1121 AAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gauuucUACCUGUUAACCGAUu 5'
                :||  || ||||||| 
Target 5' tctcccGTGCCCACTTGGCTAt 3'
 923 - 944 152.00 -9.00
2 
miRNA  3' gauuucUACCU--GU-UAACCGauu 5'
                |||||  ||  |||||   
Target 5' tcccctATGGATTCATCTTGGCctg 3'
 207 - 231 114.00 -9.50
3 
miRNA  3' gauuUCUACCUGU--UAACCGAUu 5'
              :| |||:||   || |||: 
Target 5' cagtGGCTGGGCACTCTTTGCTGc 3'
 171 - 194 108.00 -7.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN15924136 19 COSMIC
COSN30144822 25 COSMIC
COSN30152501 35 COSMIC
COSN28745949 39 COSMIC
COSN15625797 42 COSMIC
COSN18717389 114 COSMIC
COSN31540397 150 COSMIC
COSN15625798 163 COSMIC
COSN17037982 167 COSMIC
COSN30133745 234 COSMIC
COSN28697168 235 COSMIC
COSN28713552 269 COSMIC
COSN31566100 305 COSMIC
COSN15625799 335 COSMIC
COSN31579229 390 COSMIC
COSN15625800 425 COSMIC
COSN17038010 443 COSMIC
COSN5864297 473 COSMIC
COSN15625801 496 COSMIC
COSN26482368 758 COSMIC
COSN30533055 808 COSMIC
COSN31522558 849 COSMIC
COSN30170227 903 COSMIC
COSN15625802 928 COSMIC
COSN30129768 929 COSMIC
COSN28805039 953 COSMIC
COSN30125510 1012 COSMIC
COSN30532978 1024 COSMIC
COSN26641255 1046 COSMIC
COSN31544283 1049 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1402059498 1 dbSNP
rs1490971519 3 dbSNP
rs1442795694 11 dbSNP
rs1197893247 12 dbSNP
rs774436317 16 dbSNP
rs761785741 18 dbSNP
rs1429468596 24 dbSNP
rs767449904 26 dbSNP
rs750282710 27 dbSNP
rs766216071 31 dbSNP
rs1164252080 32 dbSNP
rs766005671 33 dbSNP
rs771479742 33 dbSNP
rs753520092 38 dbSNP
rs1406633653 42 dbSNP
rs1301208279 47 dbSNP
rs568107412 51 dbSNP
rs764744259 52 dbSNP
rs1030388488 53 dbSNP
rs1175745751 56 dbSNP
rs879943530 61 dbSNP
rs1447398336 63 dbSNP
rs1261221314 64 dbSNP
rs997420721 65 dbSNP
rs1028939164 69 dbSNP
rs535701855 74 dbSNP
rs1273962391 79 dbSNP
rs989798032 86 dbSNP
rs914223889 87 dbSNP
rs1008519389 89 dbSNP
rs1370857513 93 dbSNP
rs1031483210 94 dbSNP
rs967150187 98 dbSNP
rs956178105 108 dbSNP
rs1369562141 116 dbSNP
rs554119457 117 dbSNP
rs1021263163 118 dbSNP
rs572112580 120 dbSNP
rs1460486445 121 dbSNP
rs1415533171 125 dbSNP
rs928792424 129 dbSNP
rs1475585010 131 dbSNP
rs938873876 135 dbSNP
rs143202367 136 dbSNP
rs1470025033 141 dbSNP
rs1253675840 151 dbSNP
rs916136737 155 dbSNP
rs1213092048 160 dbSNP
rs1467218260 163 dbSNP
rs1275638317 165 dbSNP
rs375355102 166 dbSNP
rs557698795 168 dbSNP
rs931567723 170 dbSNP
rs1048352911 171 dbSNP
rs1339136823 173 dbSNP
rs751129201 177 dbSNP
rs1225704594 185 dbSNP
rs1202443606 189 dbSNP
rs942295272 197 dbSNP
rs1004293423 204 dbSNP
rs576468779 206 dbSNP
rs1037919757 207 dbSNP
rs900513967 212 dbSNP
rs932005610 218 dbSNP
rs1051765740 222 dbSNP
rs1248559353 224 dbSNP
rs1455436607 230 dbSNP
rs1041555737 234 dbSNP
rs7291867 235 dbSNP
rs1234744465 238 dbSNP
rs999600942 239 dbSNP
rs1031932904 242 dbSNP
rs1271537200 243 dbSNP
rs1169689374 259 dbSNP
rs780867401 262 dbSNP
rs1028838023 268 dbSNP
rs1303615029 270 dbSNP
rs1233184989 283 dbSNP
rs1364868059 284 dbSNP
rs953237430 285 dbSNP
rs1442807054 292 dbSNP
rs1353803134 293 dbSNP
rs1306135636 296 dbSNP
rs1436277980 301 dbSNP
rs1375847446 302 dbSNP
rs1011945823 304 dbSNP
rs747643188 308 dbSNP
rs755687181 311 dbSNP
rs561745414 315 dbSNP
rs1458002899 323 dbSNP
rs1231605464 327 dbSNP
rs1035300514 332 dbSNP
rs529257888 333 dbSNP
rs1486196911 336 dbSNP
rs778072830 336 dbSNP
rs373099667 337 dbSNP
rs147381408 340 dbSNP
rs1209665965 341 dbSNP
rs1368767271 346 dbSNP
rs908037639 350 dbSNP
rs1285938147 360 dbSNP
rs749813705 365 dbSNP
rs1436933050 367 dbSNP
rs1371982317 375 dbSNP
rs928362811 381 dbSNP
rs559640282 383 dbSNP
rs1361479476 385 dbSNP
rs1355824054 386 dbSNP
rs959794006 387 dbSNP
rs557173398 392 dbSNP
rs1213049672 401 dbSNP
rs1292352046 411 dbSNP
rs1464379985 416 dbSNP
rs973558671 422 dbSNP
rs1322374861 425 dbSNP
rs1160108795 426 dbSNP
rs1400133003 427 dbSNP
rs1487577054 429 dbSNP
rs1221012225 430 dbSNP
rs1167730716 431 dbSNP
rs991585845 433 dbSNP
rs1466652684 439 dbSNP
rs1475842686 448 dbSNP
rs922217269 456 dbSNP
rs1247835095 469 dbSNP
rs573828964 477 dbSNP
rs533481538 478 dbSNP
rs1315797278 479 dbSNP
rs551934818 481 dbSNP
rs60704627 486 dbSNP
rs935434560 504 dbSNP
rs772401971 519 dbSNP
rs139511515 530 dbSNP
rs1458781221 531 dbSNP
rs1041085158 534 dbSNP
rs557922549 536 dbSNP
rs1320922031 537 dbSNP
rs1430364058 539 dbSNP
rs901223748 545 dbSNP
rs996935995 546 dbSNP
rs905811927 553 dbSNP
rs1417724483 556 dbSNP
rs1001377767 559 dbSNP
rs1430601416 565 dbSNP
rs1420737319 569 dbSNP
rs1035336578 573 dbSNP
rs1464200284 573 dbSNP
rs1245843339 575 dbSNP
rs1214975530 576 dbSNP
rs149884343 580 dbSNP
rs1272410301 581 dbSNP
rs888980128 583 dbSNP
rs1309035252 584 dbSNP
rs1296072708 588 dbSNP
rs1380242060 591 dbSNP
rs58081851 594 dbSNP
rs963453852 603 dbSNP
rs1291521269 604 dbSNP
rs1331794129 609 dbSNP
rs535458618 611 dbSNP
rs1209932876 614 dbSNP
rs1284241165 615 dbSNP
rs1355457347 631 dbSNP
rs1170132381 635 dbSNP
rs1448082463 642 dbSNP
rs1387870047 643 dbSNP
rs1445630922 651 dbSNP
rs1021983504 653 dbSNP
rs1260423174 656 dbSNP
rs1212749588 661 dbSNP
rs1238785193 662 dbSNP
rs554080799 663 dbSNP
rs565945362 681 dbSNP
rs1415050864 698 dbSNP
rs1204127951 707 dbSNP
rs953626307 709 dbSNP
rs1035328489 710 dbSNP
rs144875237 711 dbSNP
rs41283237 712 dbSNP
rs74406826 716 dbSNP
rs1052858198 723 dbSNP
rs772968583 724 dbSNP
rs1393240672 726 dbSNP
rs1374644201 728 dbSNP
rs915368353 731 dbSNP
rs543468924 735 dbSNP
rs946784754 742 dbSNP
rs1359897908 754 dbSNP
rs555454330 755 dbSNP
rs182290544 760 dbSNP
rs8142832 761 dbSNP
rs762976337 771 dbSNP
rs1057013114 773 dbSNP
rs1481940741 773 dbSNP
rs559521611 778 dbSNP
rs940299249 779 dbSNP
rs976709007 784 dbSNP
rs1344523846 791 dbSNP
rs1254519084 793 dbSNP
rs1241192036 797 dbSNP
rs766264060 799 dbSNP
rs1229159676 803 dbSNP
rs60518788 812 dbSNP
rs932715350 818 dbSNP
rs1349172859 822 dbSNP
rs545424325 823 dbSNP
rs1357729673 833 dbSNP
rs1049867824 847 dbSNP
rs563857292 848 dbSNP
rs377454345 850 dbSNP
rs947183027 854 dbSNP
rs186641294 855 dbSNP
rs1471591565 862 dbSNP
rs1259325253 865 dbSNP
rs1188344441 871 dbSNP
rs903062757 872 dbSNP
rs1207179262 874 dbSNP
rs1351494577 876 dbSNP
rs1019228987 880 dbSNP
rs998733680 884 dbSNP
rs549869452 885 dbSNP
rs767152969 886 dbSNP
rs568184303 889 dbSNP
rs1174074271 890 dbSNP
rs1012608218 891 dbSNP
rs1022693172 899 dbSNP
rs1425640947 900 dbSNP
rs774986873 918 dbSNP
rs1383628883 921 dbSNP
rs1433923804 923 dbSNP
rs529026494 927 dbSNP
rs952513337 928 dbSNP
rs1410447794 929 dbSNP
rs73887026 930 dbSNP
rs1015765425 932 dbSNP
rs961926307 936 dbSNP
rs1334461435 938 dbSNP
rs755562545 939 dbSNP
rs1276011316 940 dbSNP
rs1366573213 942 dbSNP
rs573678588 944 dbSNP
rs940588105 945 dbSNP
rs1036040213 949 dbSNP
rs1247670569 949 dbSNP
rs898811823 950 dbSNP
rs142244966 953 dbSNP
rs766550436 957 dbSNP
rs1028715463 962 dbSNP
rs932661367 971 dbSNP
rs71324866 973 dbSNP
rs1209823986 977 dbSNP
rs1354680846 979 dbSNP
rs539718825 981 dbSNP
rs754262369 987 dbSNP
rs946827781 990 dbSNP
rs1195804007 997 dbSNP
rs1229128716 999 dbSNP
rs1043244532 1000 dbSNP
rs551392231 1001 dbSNP
rs757753268 1005 dbSNP
rs1057008471 1010 dbSNP
rs1326494689 1010 dbSNP
rs1404739245 1012 dbSNP
rs1388286783 1028 dbSNP
rs895468362 1029 dbSNP
rs779338518 1033 dbSNP
rs1389708355 1034 dbSNP
rs191839229 1036 dbSNP
rs1044081814 1037 dbSNP
rs183826155 1048 dbSNP
rs988770124 1049 dbSNP
rs1191525836 1050 dbSNP
rs1275747233 1051 dbSNP
rs967987323 1052 dbSNP
rs1341915517 1059 dbSNP
rs1273449595 1061 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_020315 | 3UTR | UCUCCCGUGCCCACUUGGCUAUUUACUUAUUUAUUUAUUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_020315 | 3UTR | CCCCCUGUGCGGUCAGUGUUUUCAGUACCACCUCUCUCCCGUGCCCACUUGGCUAUUUACUUAUUUAUUUAUUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_020315 | 3UTR | GGCUUUCGUGUCCCCCUGUGCGGUCAGUGUUUUCAGUACCACCUCUCUCCCGUGCCCACUUGGCUAUUUACUUAUUUAUUUAUUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_020315 | 3UTR | UUCGUGUCCCCCUGUGCGGUCAGUGUUUUCAGUACCACCUCUCUCCCGUGCCCACUUGGCUAUUUACUUAUUUAUUUAUUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_020315 | 3UTR | UGGCUAUUUACUUAUUUAUUUAUUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_020315 | 3UTR | CAGCUCGAAGGGGGGCUUUCGUGUCCCCCUGUGCGGUCAGUGUUUUCAGUACCACCUCUCUCCCGUGCCCACUUGGCUAUUUACUUAUUUAUUUAUUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000215904.6 | 3UTR | CUAUUUACUUAUUUAUUUAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
137 hsa-miR-4662a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT106793 TMEM245 transmembrane protein 245 2 2
MIRT148293 RNF138 ring finger protein 138 2 2
MIRT231332 KLHL20 kelch like family member 20 2 2
MIRT301381 PDXP pyridoxal phosphatase 2 2
MIRT441375 PAPOLA poly(A) polymerase alpha 2 4
MIRT441444 MTX3 metaxin 3 2 2
MIRT441500 SPG20 spartin 2 6
MIRT441517 ZBTB10 zinc finger and BTB domain containing 10 2 2
MIRT441562 LMOD3 leiomodin 3 2 2
MIRT441619 ROCK1 Rho associated coiled-coil containing protein kinase 1 2 6
MIRT441633 KDM5A lysine demethylase 5A 2 2
MIRT441705 ZIC4 Zic family member 4 2 2
MIRT441713 FGF9 fibroblast growth factor 9 2 2
MIRT441779 TXN thioredoxin 2 2
MIRT441917 ACADSB acyl-CoA dehydrogenase, short/branched chain 2 2
MIRT441963 BACE2 beta-site APP-cleaving enzyme 2 2 2
MIRT441974 KPNA1 karyopherin subunit alpha 1 2 2
MIRT441977 ZNF70 zinc finger protein 70 2 4
MIRT442043 SEC62 SEC62 homolog, preprotein translocation factor 2 2
MIRT442050 KLHDC10 kelch domain containing 10 2 2
MIRT442150 INTS6 integrator complex subunit 6 2 2
MIRT442186 HOOK3 hook microtubule tethering protein 3 2 2
MIRT442255 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT442280 CCDC108 cilia and flagella associated protein 65 2 4
MIRT442353 OLA1 Obg like ATPase 1 2 4
MIRT442644 NAMPT nicotinamide phosphoribosyltransferase 2 2
MIRT442662 GLRA2 glycine receptor alpha 2 2 2
MIRT442782 HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 2 2
MIRT442861 SCARF1 scavenger receptor class F member 1 2 4
MIRT442900 SOD2 superoxide dismutase 2 2 2
MIRT442922 TFDP2 transcription factor Dp-2 2 2
MIRT442930 RWDD1 RWD domain containing 1 2 2
MIRT442939 CA5B carbonic anhydrase 5B 2 2
MIRT443014 C21orf91 chromosome 21 open reading frame 91 2 2
MIRT443139 ZDHHC21 zinc finger DHHC-type containing 21 2 2
MIRT443576 PPIC peptidylprolyl isomerase C 2 2
MIRT443584 FAM84B family with sequence similarity 84 member B 2 2
MIRT443596 VAT1L vesicle amine transport 1 like 2 2
MIRT443771 STS steroid sulfatase 2 2
MIRT443870 DDTL D-dopachrome tautomerase like 2 2
MIRT452489 BANK1 B-cell scaffold protein with ankyrin repeats 1 2 16
MIRT461187 TRIP4 thyroid hormone receptor interactor 4 2 16
MIRT464093 VPS36 vacuolar protein sorting 36 homolog 2 2
MIRT466637 TAOK1 TAO kinase 1 2 17
MIRT466642 TAGLN2 transgelin 2 2 2
MIRT469936 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT489810 LSP1 lymphocyte-specific protein 1 2 4
MIRT490549 TEX261 testis expressed 261 2 4
MIRT495069 PAQR7 progestin and adipoQ receptor family member 7 2 2
MIRT496723 SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 2 2
MIRT496881 PLA2G16 phospholipase A2 group XVI 2 2
MIRT497017 INO80B INO80 complex subunit B 2 2
MIRT498347 CISD1 CDGSH iron sulfur domain 1 2 2
MIRT498353 ABHD17B abhydrolase domain containing 17B 2 2
MIRT503294 GTF2A1 general transcription factor IIA subunit 1 2 6
MIRT504529 ZNF620 zinc finger protein 620 2 6
MIRT507283 FEM1B fem-1 homolog B 2 2
MIRT507540 DHX33 DEAH-box helicase 33 2 2
MIRT509090 SYNPO2L synaptopodin 2 like 2 4
MIRT510083 PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2 8
MIRT510702 SREK1IP1 SREK1 interacting protein 1 2 4
MIRT511355 ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein like 2 2 6
MIRT513119 OSBPL3 oxysterol binding protein like 3 2 2
MIRT515209 CRCP CGRP receptor component 2 2
MIRT516376 TRAF3IP2 TRAF3 interacting protein 2 2 4
MIRT520307 UBXN2A UBX domain protein 2A 2 2
MIRT521124 SHROOM4 shroom family member 4 2 2
MIRT522049 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT522947 IPO9 importin 9 2 2
MIRT524418 CNKSR3 CNKSR family member 3 2 2
MIRT525073 FRK fyn related Src family tyrosine kinase 2 2
MIRT525150 ZNF329 zinc finger protein 329 2 2
MIRT528538 TTC22 tetratricopeptide repeat domain 22 2 2
MIRT530560 AKNA AT-hook transcription factor 2 2
MIRT530653 TRIM56 tripartite motif containing 56 2 2
MIRT530823 TMED3 transmembrane p24 trafficking protein 3 2 2
MIRT535689 NEURL1B neuralized E3 ubiquitin protein ligase 1B 2 2
MIRT536881 HIF1A hypoxia inducible factor 1 alpha subunit 2 4
MIRT538295 CSNK2A1 casein kinase 2 alpha 1 2 2
MIRT538783 C6orf89 chromosome 6 open reading frame 89 2 2
MIRT540735 FN3KRP fructosamine 3 kinase related protein 2 2
MIRT540828 GNAT1 G protein subunit alpha transducin 1 2 4
MIRT549086 C5orf51 chromosome 5 open reading frame 51 2 2
MIRT549547 CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 2 2
MIRT550203 MAVS mitochondrial antiviral signaling protein 2 4
MIRT555299 PPP4R2 protein phosphatase 4 regulatory subunit 2 2 2
MIRT563173 ZRANB3 zinc finger RANBP2-type containing 3 2 2
MIRT563973 HCFC1 host cell factor C1 2 2
MIRT564610 ZNF703 zinc finger protein 703 2 2
MIRT565345 TMED4 transmembrane p24 trafficking protein 4 2 2
MIRT566437 PHF16 jade family PHD finger 3 1 1
MIRT573087 APLN apelin 2 2
MIRT617053 ZNF677 zinc finger protein 677 2 2
MIRT617404 API5 apoptosis inhibitor 5 2 2
MIRT617459 CCS copper chaperone for superoxide dismutase 2 2
MIRT618191 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT619003 NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 2 2
MIRT619853 KIR3DX1 killer cell immunoglobulin like receptor, three Ig domains X1 2 2
MIRT622214 SLC39A11 solute carrier family 39 member 11 2 2
MIRT622455 RNF19B ring finger protein 19B 2 2
MIRT622495 RBMS1 RNA binding motif single stranded interacting protein 1 2 2
MIRT623408 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT626501 ZNF25 zinc finger protein 25 2 2
MIRT636142 WDR37 WD repeat domain 37 2 2
MIRT640645 IGF2 insulin like growth factor 2 2 2
MIRT644638 ICA1L islet cell autoantigen 1 like 2 2
MIRT646673 CCDC69 coiled-coil domain containing 69 2 2
MIRT650041 VHL von Hippel-Lindau tumor suppressor 2 2
MIRT651907 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT655712 MLF2 myeloid leukemia factor 2 2 2
MIRT655965 NDNF neuron derived neurotrophic factor 2 2
MIRT656110 MSRB3 methionine sulfoxide reductase B3 2 2
MIRT658154 FCHSD2 FCH and double SH3 domains 2 2 2
MIRT661945 FAHD1 fumarylacetoacetate hydrolase domain containing 1 2 2
MIRT664457 WDR92 WD repeat domain 92 2 2
MIRT671622 C20orf144 chromosome 20 open reading frame 144 2 4
MIRT677168 ZNF786 zinc finger protein 786 2 2
MIRT679004 UBN2 ubinuclein 2 2 2
MIRT679181 XIAP X-linked inhibitor of apoptosis 2 2
MIRT679343 PPP1R3B protein phosphatase 1 regulatory subunit 3B 2 2
MIRT679439 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT682503 GLP2R glucagon like peptide 2 receptor 2 2
MIRT683558 SMIM12 small integral membrane protein 12 2 2
MIRT687136 QPCTL glutaminyl-peptide cyclotransferase like 2 2
MIRT687722 KIAA1467 family with sequence similarity 234 member B 2 2
MIRT688411 DUSP2 dual specificity phosphatase 2 2 2
MIRT694684 CD300LG CD300 molecule like family member g 2 2
MIRT695390 WDR41 WD repeat domain 41 2 2
MIRT696136 ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 2 2
MIRT699113 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT702771 IFNLR1 interferon lambda receptor 1 2 2
MIRT704096 DST dystonin 2 2
MIRT704279 DENND5B DENN domain containing 5B 2 2
MIRT707692 FAM118A family with sequence similarity 118 member A 2 2
MIRT708060 LIX1L limb and CNS expressed 1 like 2 2
MIRT710078 BEND3 BEN domain containing 3 2 2
MIRT725480 GPR26 G protein-coupled receptor 26 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4662a Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-4662a-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4662a-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-4662a-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-4662a-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)

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