miRTarBase - #MIRT310455


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pre-miRNA Information
pre-miRNA hsa-mir-646   
Genomic Coordinates chr20: 60308474 - 60308567
Synonyms MIRN646, hsa-mir-646, MIR646
Description Homo sapiens miR-646 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-646
Sequence 61| AAGCAGCUGCCUCUGAGGC |79
Evidence Experimental
Experiments SAGE
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs750684400 6 dbSNP
rs112880289 10 dbSNP
rs553679341 11 dbSNP
rs941692683 13 dbSNP
rs6513497 14 dbSNP
rs1431341059 18 dbSNP
rs1479355932 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol REST   
Synonyms NRSF, WT6, XBR
Description RE1 silencing transcription factor
Transcript NM_005612   
Expression
Putative miRNA Targets on REST
3'UTR of REST
(miRNA target sites are highlighted)		 
>REST|NM_005612|3'UTR
   1 TGAAACTTTGAACAAGGTTTCAGTTCTTAGTTTGTAAGGTATATTACATTTTATATTCATTTATGATAGCAGACAACCTT
  81 TTAAGATTGCTTTAATTAGTATCTGATGTTGATTTTTAAGTGGCATTCTTTTCCTTAGGACTTTTTATGTATACCTGTTG
 161 ATTGTTGTGTAAATTTTAGTAAATCTAAGAGAGTGTACTAAACCAGCAGGTATCTGTTAGCTTATGTGTTTAATTGAAAT
 241 TAGAAGGCTAAGATGGTATAACAGCATTTTATTGCTTTGTCCAGCTACAACTTGTCATTTTTTTCTCCATGTCTTATCTT
 321 CCTGTTTCACTTTAGTTTATTCTTCGTTTTTTATTGAGATCTATAAAAAATTGGCTTACTTAATAGCAAATTACTTGAAG
 401 AATTTGCCTGCTTTATATAAAGTTAGCACTTTAAGATTTTTTTTTTTAGAGATGAGAAGACATTTAAATTGAAGAAAAAT
 481 TCCCCCAGCAATAGACAGTCTATCAGTCCAAGTATTTACTTCCTGAGTTTTGATCAATATTTTTTATTTGTGTATGTTAA
 561 TCGTCATAAAAACAGTGATTTTGGTGTGTTTTTTATTTTGGTGCTTTAATGGCTTAAGATGTTGCACATTTTTTTTTTCT
 641 TTTGGTTTCTGTTTATGTTTTTTTGCCTATGCAGTTAAATTTTTCCTAGAAATAGCATTTGTGTTGAACAGTAACACTTT
 721 ATACATATATATATGCATGTTTATTTTGTTTGGCGTCTTTGGAGGGATGCTTTTAGACTTGTTTGCAAAAGGGCAGTTTT
 801 CTTTTTCTTTGCTGCAGTTGTCTATTTTGCAGAATAATAGTGTGTGCAAGTTTGTGAGCAAATGAAATATGCAGGTTCAA
 881 TCTATTGATTTTGATTTTTACATCTTATATCTATGCCAGAATCTGTATTTCATATAACTTATTTATTTCGAATGGATGTA
 961 GTAAATTCACAGCTATCAGTTTTGATTTTGCAATAAATAAACCACTAGGTTGCATGTCGAACAAATTTTTATCTCAAATA
1041 CCAACCATCAGTTTTTTTTTTCATGTGTTTTGGTACAGCTAATTCCTAATTGTAGAGTGTTAAATGTTTGAGGAGAACCT
1121 TTTCTCATAGATGGTTGGTGTTCATATGGCTACTTTACAATAAAGAGAACTGTAAGTGATATTTGGAAACTACAAACCTG
1201 GAATTAGGAGATATAATTATTCCTTCAAGTTTTATAGAATATCACTTGGGAGATTCCAAAGCCATAGCTATTACGCGGCA
1281 AACCTAGGATAAGAAAGGTAGTATGAGTGCTGGTAGACCAGCTGCAACTTTCCTATACAGTGAAAAAGGCTGGTGAAACA
1361 AGTACAGTCCAGATTTTTTAAAATCATACTTTCTCAGGGATCTCCACAAACTGGTGGGTGTCCTGGCTGTCTGTGTGATA
1441 GCCTCTTTCTATAGGTGAGGCCTCAAATGAATTGCAGCTATCCTGGTGTTCCTATGAGGGCACTTTGTATGAAAAAGGGC
1521 ATGTACTCCAAAACATTTTTGTAGGTTCTTTGGCCAGTTGCCAAAGAGTGTGAAAGAATCCAATAGAGGATTTTTCTTAC
1601 TGATAGCAGTCATTCATTGCAGTAAAATAAAATATGATCCCATTAGGGAATCTTGAATTCTGACCTCCCATACTCCGTTT
1681 TGAAATAACCACTTTATATTTCATTTTTTAAAAATCTGATGATCTCTTTGAGGCAGGTTTCAGATTTGGCAGTACAACAT
1761 GAAAGATTAGGAAAAGCATTAATAACGTGTGGGTGGAAAGCTTGTTAAAAATCTGAGAGTGAAGTTTGAGTTAAAAGTTG
1841 TTTGAACATGGCATTGACTGGGAGGCCAAAGATTTAAAGAAGCGGAAGATTCTTCTCTTAAGACATGAGGAGTAAGTTGT
1921 GTGATAATGGTATGTGTTTTGTGTGCATGAATGGACATTGTAAATGTTGAATTCTAGGCTCCGACAATCATTGTCAACAG
2001 AAGATCAAGCTGCAAATATTTATGTTTTAAAACTTAAATTATAAAGCTAGTTAAGTCTTTCTAATGACTAGTTTTAATGT
2081 TCATGGGTACATTTTACCTAAGTTACCGTTTACATTGTATAGAAAAAGATACATCTTAAGCACAGATTGGTTATTAGGAA
2161 TTAGTTTGGGGAAGAGGTTTTTTTGTGGATTCTTTCATACTGCAAAGAAAAACCATTTGCCTTTTGGGGAATTGAGCTAA
2241 CTTCTAATCTAGTCTTAAGACTAGAATGCTAAAAACAAAAACATGAAGGAAATTAAAACCCCTTATTATTAAATTGATTT
2321 GTAAAAACATTGTTACTGGAAATTTATTGGACTTGAGGCCTTCCTCCAGAAAATAAGGACTTGATTGTCAGGCCTATATT
2401 AGGTTCTGAACCTTAATGCCATGTATTTGTACTTACTAAAAATTGTTTCAATGAAAAGTACATTAGCAGTATGAACTTCT
2481 GGTCCAGTTGGAAGTTTTTCCATTTGAAAAATGTGATGTTTGCATGGAACTGTTTGAAACTTTTTTATTTTCTAGTCCCC
2561 CTCCCCCACACTGGATAGAATTTAGCCTAGAATTTTCCCTTTGGATAAAAGAACAAAAATTGAACATGTTATTTGTAAAT
2641 TGATGTTTAGTAATTAGTGATAAACTTGAAATACTAGCATATATTATAAGCCTTAATCTTAGGTAGTCTTATGAAAATGA
2721 ATCTCTTAACTATCTTTTGAACCTGTATTCACATTGGTTTTCAAGATATTTTAAGTTATATTTTTTCCTCTTTTCAGAGC
2801 TGCTTCTTATTCTGGGGCTACTTTTTTTTTTAGTTGTGTAATTCACAAAGGGCTGCATTTTTTTTTTTTTTTAATAAGGC
2881 TTATAACTATGGCTGGATCTTTTGCTCTAGTCTTCTAAGAAGGGCCATTTTATTTTTTAGAGTCACTTCTAAAGTCATGT
2961 GGTAATTAACTTTGGAGACTGTTTTGCGTATGAGTGCTGATACAAATTAAAACCCAAGTAGACCTCATTGCATGTCACCC
3041 TATGAATGTTGACAATGGAAGGAATACCTTGCCTGTAGTATACTGTCACTTCTGGATTGATAAGCTGAGGAAGAAAGTTA
3121 AGTTTCTTTTTTACATAAGTCAGAAAAACTTACAGCTGGTGTTCCTAGTTTCCTGGTTGACCTCAGCAGATGAAGTGAAC
3201 AGATAGTGTTAATTCAGATTGAAGAAATTATCTGAATCTTGGTTTGTGTAGATTTACAATCTACATGCAATATTAACTAA
3281 ATCAGATAGCTTTTACAGTTTCACATGTGTACATAGGTTCCCTCCCGGTCCCTTCCATATCCATTAGTTATTGAACTTTC
3361 TAAACTGGCATTGAAACATTACAACAATGTTTTGTTGCACCAATTTTATAAACTTAAGCAGTGCAATACGTGTTACTTTT
3441 CTGAGGCAAACCAAAGGTAAATTTCTCAAGGTTCTTGCTGCCTTCTTTAGCAGCATTTGATGGAAGATCTTTTATACATT
3521 TGTAATAGATAAAAATAAACCAGATTGCAAATCCTTTTTTAAAATCCTAAACCATGTACCAAGTTTTTGGTCCAAATTAT
3601 GTAGGATAAGTTAAACTTAAATTGCATTCTATTAACCAATATGAGTGTATTTCTGTAAGCATAGTTATGTTGAAATAAAG
3681 TTTTAAAAACCA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgGAGUCUCCGUCGACGAa 5'
            :||||    ||||||| 
Target 5' ttTTCAG----AGCTGCTt 3'
 2791 - 2805 147.00 -13.90
2 
miRNA  3' cggaGUCUCCGUCGACGaa 5'
              :|||  |||||||  
Target 5' ctggTAGA-CCAGCTGCaa 3'
 1310 - 1327 130.00 -11.60
3 
miRNA  3' cggaGUCUCC--G-UCGACGaa 5'
              |||| |  | ||||||  
Target 5' tcaaCAGAAGATCAAGCTGCaa 3'
 1994 - 2015 129.00 -12.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1178578 152 ClinVar
COSN31598583 16 COSMIC
COSN7496094 208 COSMIC
COSN26827808 423 COSMIC
COSN9045677 536 COSMIC
COSN21958367 544 COSMIC
COSN31962270 564 COSMIC
COSN31657271 748 COSMIC
COSN28981730 1062 COSMIC
COSN17286607 1546 COSMIC
COSN15912395 1977 COSMIC
COSN21104754 2109 COSMIC
COSN1298708 2586 COSMIC
COSN22698480 3404 COSMIC
COSN24324104 3669 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1336936895 2 dbSNP
rs772278505 7 dbSNP
rs1230728158 9 dbSNP
rs1289068538 14 dbSNP
rs760840538 15 dbSNP
rs200137905 16 dbSNP
rs1257978702 19 dbSNP
rs1336763256 20 dbSNP
rs1470760885 23 dbSNP
rs760970217 25 dbSNP
rs771157425 34 dbSNP
rs777034707 35 dbSNP
rs1409231394 41 dbSNP
rs759954686 42 dbSNP
rs765732930 43 dbSNP
rs1250506393 44 dbSNP
rs762391711 48 dbSNP
rs1043869611 57 dbSNP
rs571466291 60 dbSNP
rs1185291160 61 dbSNP
rs1441729494 66 dbSNP
rs1365923374 68 dbSNP
rs1406735624 70 dbSNP
rs1000173060 71 dbSNP
rs1204318176 73 dbSNP
rs1031013524 75 dbSNP
rs1306078518 77 dbSNP
rs770018766 79 dbSNP
rs1334115375 83 dbSNP
rs1351818364 89 dbSNP
rs536844723 97 dbSNP
rs1441556997 108 dbSNP
rs1013680176 118 dbSNP
rs1327683964 119 dbSNP
rs972824793 120 dbSNP
rs1315147835 125 dbSNP
rs557258216 142 dbSNP
rs1386073119 143 dbSNP
rs1319446146 150 dbSNP
rs781667 152 dbSNP
rs1386906761 156 dbSNP
rs1161190412 158 dbSNP
rs931227818 161 dbSNP
rs1049707640 163 dbSNP
rs1375816483 165 dbSNP
rs536276722 168 dbSNP
rs909034757 169 dbSNP
rs962003504 172 dbSNP
rs1208386148 177 dbSNP
rs1447752650 180 dbSNP
rs911049680 184 dbSNP
rs1208367351 188 dbSNP
rs145052321 196 dbSNP
rs1041088680 198 dbSNP
rs1293123737 205 dbSNP
rs1360591905 207 dbSNP
rs1225443684 208 dbSNP
rs902623197 209 dbSNP
rs533864838 215 dbSNP
rs1362360418 217 dbSNP
rs1296175436 227 dbSNP
rs922963350 228 dbSNP
rs763331656 231 dbSNP
rs999502917 232 dbSNP
rs1181925122 233 dbSNP
rs1327770292 243 dbSNP
rs1321341979 246 dbSNP
rs1404543708 250 dbSNP
rs1366173503 255 dbSNP
rs1054202649 263 dbSNP
rs572986400 264 dbSNP
rs1427703042 265 dbSNP
rs1388427380 268 dbSNP
rs560639617 270 dbSNP
rs774570488 275 dbSNP
rs1185948432 277 dbSNP
rs558648586 283 dbSNP
rs1012910012 290 dbSNP
rs1050040609 292 dbSNP
rs4864608 293 dbSNP
rs150938778 296 dbSNP
rs760637695 298 dbSNP
rs28613467 306 dbSNP
rs1035412021 311 dbSNP
rs1273300999 317 dbSNP
rs370943826 318 dbSNP
rs1272700136 325 dbSNP
rs556136695 326 dbSNP
rs972390071 330 dbSNP
rs1345951278 332 dbSNP
rs1304682219 334 dbSNP
rs1410404805 335 dbSNP
rs1369805251 340 dbSNP
rs763635931 346 dbSNP
rs551502862 347 dbSNP
rs564036650 347 dbSNP
rs952448612 356 dbSNP
rs1421977787 359 dbSNP
rs985329111 360 dbSNP
rs911158935 362 dbSNP
rs1384083580 364 dbSNP
rs1248631961 365 dbSNP
rs1023624013 370 dbSNP
rs943848882 372 dbSNP
rs779444757 375 dbSNP
rs969491698 375 dbSNP
rs1006283329 376 dbSNP
rs1040868936 377 dbSNP
rs1016126110 384 dbSNP
rs923992722 385 dbSNP
rs962144789 388 dbSNP
rs529515427 396 dbSNP
rs1323733484 404 dbSNP
rs1274556080 406 dbSNP
rs1284967661 413 dbSNP
rs1226345500 419 dbSNP
rs1053913829 420 dbSNP
rs1349859851 430 dbSNP
rs1202698501 433 dbSNP
rs893791300 435 dbSNP
rs11336958 437 dbSNP
rs1332220916 437 dbSNP
rs1443072466 437 dbSNP
rs397879276 437 dbSNP
rs1469494998 438 dbSNP
rs1030696398 443 dbSNP
rs542133568 447 dbSNP
rs767469589 447 dbSNP
rs1471805740 452 dbSNP
rs1407948997 463 dbSNP
rs1446007704 467 dbSNP
rs1178245367 471 dbSNP
rs542627366 483 dbSNP
rs1012272757 484 dbSNP
rs1235260946 487 dbSNP
rs985782527 489 dbSNP
rs559281722 497 dbSNP
rs1186459035 498 dbSNP
rs1372239768 501 dbSNP
rs1461546610 501 dbSNP
rs1264603936 503 dbSNP
rs910204702 506 dbSNP
rs1045319238 510 dbSNP
rs1169558258 511 dbSNP
rs947151132 520 dbSNP
rs1376812522 524 dbSNP
rs906798329 529 dbSNP
rs190192306 538 dbSNP
rs200337062 543 dbSNP
rs373699773 543 dbSNP
rs528464115 547 dbSNP
rs1336089455 555 dbSNP
rs180739700 564 dbSNP
rs141330981 567 dbSNP
rs1454740328 567 dbSNP
rs935532783 574 dbSNP
rs898034452 575 dbSNP
rs1326184033 577 dbSNP
rs1421405056 582 dbSNP
rs1412262985 584 dbSNP
rs1182513211 587 dbSNP
rs994317112 588 dbSNP
rs1228851407 600 dbSNP
rs1444694845 601 dbSNP
rs1052615138 603 dbSNP
rs369294506 604 dbSNP
rs1026766029 614 dbSNP
rs1485313220 620 dbSNP
rs1261105986 622 dbSNP
rs952461390 623 dbSNP
rs1319923999 628 dbSNP
rs985107795 628 dbSNP
rs1236737468 629 dbSNP
rs1245395870 629 dbSNP
rs1317194809 629 dbSNP
rs796271772 629 dbSNP
rs1433190517 640 dbSNP
rs143550781 640 dbSNP
rs1272413795 645 dbSNP
rs1320877755 646 dbSNP
rs1222375599 650 dbSNP
rs1263152412 652 dbSNP
rs1462392361 654 dbSNP
rs1018117261 655 dbSNP
rs1206393948 656 dbSNP
rs753343306 657 dbSNP
rs949604457 658 dbSNP
rs1045104435 670 dbSNP
rs965271667 679 dbSNP
rs1386582549 694 dbSNP
rs530762846 696 dbSNP
rs1195325041 697 dbSNP
rs1375867092 698 dbSNP
rs756962604 699 dbSNP
rs1188108914 721 dbSNP
rs1006314462 725 dbSNP
rs905172710 725 dbSNP
rs1016726033 726 dbSNP
rs935212913 729 dbSNP
rs1294051589 731 dbSNP
rs564577801 732 dbSNP
rs1225331661 733 dbSNP
rs1307197686 736 dbSNP
rs1430031914 738 dbSNP
rs1384316657 739 dbSNP
rs993775893 755 dbSNP
rs989953092 756 dbSNP
rs915348445 763 dbSNP
rs1367932506 764 dbSNP
rs948008374 767 dbSNP
rs1373341121 772 dbSNP
rs1045099275 773 dbSNP
rs1172042505 775 dbSNP
rs778550402 780 dbSNP
rs750029901 789 dbSNP
rs1199797060 812 dbSNP
rs1384768177 816 dbSNP
rs1383119528 817 dbSNP
rs939583284 821 dbSNP
rs1249519460 825 dbSNP
rs1036651561 826 dbSNP
rs550475964 830 dbSNP
rs1404826960 840 dbSNP
rs1480332139 843 dbSNP
rs1251924967 859 dbSNP
rs985981629 863 dbSNP
rs1325031192 867 dbSNP
rs1236505142 870 dbSNP
rs1017241679 871 dbSNP
rs968315742 877 dbSNP
rs1327411148 881 dbSNP
rs1350860021 883 dbSNP
rs978390559 884 dbSNP
rs1396626027 885 dbSNP
rs147719648 905 dbSNP
rs934409730 908 dbSNP
rs755332703 909 dbSNP
rs918064507 911 dbSNP
rs1200026980 912 dbSNP
rs1176968172 914 dbSNP
rs1269758786 915 dbSNP
rs1027125011 916 dbSNP
rs1481449711 917 dbSNP
rs949636705 920 dbSNP
rs1181039163 921 dbSNP
rs1045304735 924 dbSNP
rs905200353 926 dbSNP
rs758778395 935 dbSNP
rs1251353844 939 dbSNP
rs1197562610 944 dbSNP
rs1363440298 946 dbSNP
rs1460199710 947 dbSNP
rs386674682 947 dbSNP
rs115752183 950 dbSNP
rs1159084357 950 dbSNP
rs114040635 951 dbSNP
rs1160675813 952 dbSNP
rs186088023 959 dbSNP
rs965053783 961 dbSNP
rs1336807452 962 dbSNP
rs527718486 969 dbSNP
rs1308520280 970 dbSNP
rs1424629882 970 dbSNP
rs1449821707 972 dbSNP
rs1404969402 973 dbSNP
rs112072087 974 dbSNP
rs1030947000 975 dbSNP
rs1157724702 976 dbSNP
rs1346921806 978 dbSNP
rs1454252629 979 dbSNP
rs956722211 985 dbSNP
rs989341768 986 dbSNP
rs915278718 993 dbSNP
rs1184144636 996 dbSNP
rs1442833514 1004 dbSNP
rs571949421 1015 dbSNP
rs1030591767 1017 dbSNP
rs890263026 1019 dbSNP
rs1389182420 1020 dbSNP
rs770418236 1024 dbSNP
rs1305602332 1025 dbSNP
rs980892929 1032 dbSNP
rs778055054 1036 dbSNP
rs1007434045 1040 dbSNP
rs1240697374 1050 dbSNP
rs1017508739 1052 dbSNP
rs1204848384 1052 dbSNP
rs1381449363 1052 dbSNP
rs140595812 1053 dbSNP
rs1315079013 1060 dbSNP
rs999843369 1062 dbSNP
rs1358441662 1063 dbSNP
rs1223214597 1064 dbSNP
rs1031323156 1066 dbSNP
rs1479577521 1068 dbSNP
rs1387108751 1073 dbSNP
rs192197922 1077 dbSNP
rs545602834 1082 dbSNP
rs1037006317 1084 dbSNP
rs1384706509 1087 dbSNP
rs1419926575 1090 dbSNP
rs1180709339 1091 dbSNP
rs1473898906 1091 dbSNP
rs918084333 1098 dbSNP
rs564991109 1102 dbSNP
rs1192982911 1108 dbSNP
rs557237311 1109 dbSNP
rs1264259059 1132 dbSNP
rs930776065 1135 dbSNP
rs1220933398 1144 dbSNP
rs1359278187 1147 dbSNP
rs1049235160 1151 dbSNP
rs1380167442 1154 dbSNP
rs888153582 1160 dbSNP
rs1368018517 1165 dbSNP
rs942239308 1168 dbSNP
rs1431254347 1171 dbSNP
rs1460876405 1182 dbSNP
rs1301007650 1183 dbSNP
rs1404269003 1190 dbSNP
rs1366041159 1192 dbSNP
rs1038135228 1194 dbSNP
rs866706864 1198 dbSNP
rs184080847 1202 dbSNP
rs1396556878 1208 dbSNP
rs1475838919 1211 dbSNP
rs1426251639 1214 dbSNP
rs542866271 1215 dbSNP
rs1312451887 1222 dbSNP
rs1051815983 1227 dbSNP
rs1270218938 1229 dbSNP
rs559610654 1235 dbSNP
rs1435534087 1240 dbSNP
rs1316816012 1241 dbSNP
rs1271628491 1246 dbSNP
rs1059741 1257 dbSNP
rs1059740 1258 dbSNP
rs528500809 1260 dbSNP
rs1340963612 1275 dbSNP
rs1007386751 1276 dbSNP
rs1203683407 1277 dbSNP
rs550288590 1278 dbSNP
rs186053445 1287 dbSNP
rs1352863648 1290 dbSNP
rs1328198047 1296 dbSNP
rs1000090843 1298 dbSNP
rs1402725536 1301 dbSNP
rs1480987411 1304 dbSNP
rs1174798724 1305 dbSNP
rs1714003 1311 dbSNP
rs1200820593 1313 dbSNP
rs1480300558 1320 dbSNP
rs1031773791 1340 dbSNP
rs1193457091 1342 dbSNP
rs1469010010 1356 dbSNP
rs1231822677 1358 dbSNP
rs759754653 1368 dbSNP
rs1014431585 1369 dbSNP
rs1260848370 1380 dbSNP
rs1184617404 1387 dbSNP
rs1416360732 1392 dbSNP
rs1024092988 1396 dbSNP
rs1284911682 1397 dbSNP
rs771809574 1400 dbSNP
rs1222024369 1402 dbSNP
rs781031215 1403 dbSNP
rs1372444827 1409 dbSNP
rs969791607 1410 dbSNP
rs980958211 1413 dbSNP
rs926763737 1414 dbSNP
rs963634429 1417 dbSNP
rs1407326324 1418 dbSNP
rs1178614165 1426 dbSNP
rs973656146 1428 dbSNP
rs919253429 1431 dbSNP
rs929289011 1444 dbSNP
rs530876526 1446 dbSNP
rs550763721 1450 dbSNP
rs912000710 1451 dbSNP
rs943444502 1452 dbSNP
rs1038857885 1456 dbSNP
rs1463068981 1459 dbSNP
rs904343287 1460 dbSNP
rs760674050 1467 dbSNP
rs1316328025 1472 dbSNP
rs1284844683 1478 dbSNP
rs1241012367 1481 dbSNP
rs1053009411 1491 dbSNP
rs1338490024 1495 dbSNP
rs567424680 1498 dbSNP
rs1383711516 1500 dbSNP
rs1359563449 1507 dbSNP
rs1059739 1519 dbSNP
rs1213963367 1521 dbSNP
rs891701163 1531 dbSNP
rs1160515230 1541 dbSNP
rs1422007033 1548 dbSNP
rs1296191564 1549 dbSNP
rs1308223856 1550 dbSNP
rs1013958763 1552 dbSNP
rs1444938813 1557 dbSNP
rs1220558637 1562 dbSNP
rs1257824873 1564 dbSNP
rs1261284016 1573 dbSNP
rs1184616035 1574 dbSNP
rs1461064437 1581 dbSNP
rs1204515052 1582 dbSNP
rs150493651 1584 dbSNP
rs1357113590 1601 dbSNP
rs1289683743 1610 dbSNP
rs1485091824 1616 dbSNP
rs1322613875 1633 dbSNP
rs1315079152 1636 dbSNP
rs1213217469 1638 dbSNP
rs1186519440 1640 dbSNP
rs905638732 1641 dbSNP
rs753717050 1643 dbSNP
rs1402403202 1647 dbSNP
rs1033864930 1649 dbSNP
rs1173660386 1656 dbSNP
rs1424721327 1664 dbSNP
rs1427936836 1669 dbSNP
rs546954356 1671 dbSNP
rs963537457 1676 dbSNP
rs974070779 1677 dbSNP
rs138269723 1678 dbSNP
rs1343273015 1679 dbSNP
rs1429763919 1691 dbSNP
rs566754619 1692 dbSNP
rs1026600883 1693 dbSNP
rs1402984507 1694 dbSNP
rs867530596 1696 dbSNP
rs951015120 1697 dbSNP
rs1281502988 1704 dbSNP
rs761321874 1704 dbSNP
rs538653869 1710 dbSNP
rs558238778 1711 dbSNP
rs1224418912 1717 dbSNP
rs1344229132 1719 dbSNP
rs1283174199 1725 dbSNP
rs1280996855 1728 dbSNP
rs1392284060 1730 dbSNP
rs1315287968 1733 dbSNP
rs1295884592 1753 dbSNP
rs1215531115 1755 dbSNP
rs1354744055 1757 dbSNP
rs911863181 1759 dbSNP
rs1479320521 1760 dbSNP
rs1489572971 1774 dbSNP
rs1428562090 1775 dbSNP
rs1197852587 1779 dbSNP
rs943473884 1787 dbSNP
rs974757569 1788 dbSNP
rs1258932979 1802 dbSNP
rs1480470065 1809 dbSNP
rs1192633345 1818 dbSNP
rs1321897103 1819 dbSNP
rs1262854447 1821 dbSNP
rs925794537 1822 dbSNP
rs935881162 1823 dbSNP
rs1053362760 1835 dbSNP
rs891737681 1840 dbSNP
rs949997397 1846 dbSNP
rs1045439715 1847 dbSNP
rs1467865072 1860 dbSNP
rs1405102600 1870 dbSNP
rs1362185998 1872 dbSNP
rs1467582885 1883 dbSNP
rs1422724112 1884 dbSNP
rs1179813516 1885 dbSNP
rs1418551338 1886 dbSNP
rs1001288850 1891 dbSNP
rs905504801 1891 dbSNP
rs1242922070 1895 dbSNP
rs1345041206 1895 dbSNP
rs1201381717 1896 dbSNP
rs1405638523 1897 dbSNP
rs1347814421 1898 dbSNP
rs1276626964 1905 dbSNP
rs1237752897 1907 dbSNP
rs1353835405 1911 dbSNP
rs1310748584 1927 dbSNP
rs1450020774 1929 dbSNP
rs1016660291 1931 dbSNP
rs898231897 1952 dbSNP
rs1223389023 1958 dbSNP
rs995039165 1974 dbSNP
rs1382754956 1976 dbSNP
rs1157963809 1979 dbSNP
rs1420182486 1980 dbSNP
rs1381014415 1983 dbSNP
rs1160458138 1984 dbSNP
rs1026884715 1997 dbSNP
rs1242741450 2002 dbSNP
rs568947939 2013 dbSNP
rs1285437517 2017 dbSNP
rs1356267151 2026 dbSNP
rs562930220 2035 dbSNP
rs1444457431 2042 dbSNP
rs1260036117 2044 dbSNP
rs1205081738 2050 dbSNP
rs537503780 2056 dbSNP
rs1287626682 2064 dbSNP
rs1490637153 2065 dbSNP
rs1223158457 2068 dbSNP
rs987659190 2069 dbSNP
rs1018903152 2072 dbSNP
rs1469344830 2080 dbSNP
rs1324492565 2084 dbSNP
rs1317305935 2085 dbSNP
rs1400537998 2090 dbSNP
rs1177402104 2091 dbSNP
rs1362370853 2096 dbSNP
rs1382001088 2097 dbSNP
rs1300174055 2099 dbSNP
rs557135900 2100 dbSNP
rs1422793899 2105 dbSNP
rs1442536453 2108 dbSNP
rs1473869439 2109 dbSNP
rs964646258 2109 dbSNP
rs1371713061 2115 dbSNP
rs974705151 2118 dbSNP
rs1478469155 2131 dbSNP
rs149192051 2139 dbSNP
rs866660640 2148 dbSNP
rs1490053615 2154 dbSNP
rs957917416 2157 dbSNP
rs1211281893 2170 dbSNP
rs79178673 2172 dbSNP
rs1406973264 2178 dbSNP
rs1342341593 2181 dbSNP
rs1281267054 2189 dbSNP
rs1404216301 2198 dbSNP
rs988692511 2200 dbSNP
rs1324219329 2201 dbSNP
rs1407361770 2202 dbSNP
rs145032340 2205 dbSNP
rs1170474050 2215 dbSNP
rs1466441832 2217 dbSNP
rs1426183385 2220 dbSNP
rs1352809933 2233 dbSNP
rs950017797 2243 dbSNP
rs1441819871 2248 dbSNP
rs138876445 2253 dbSNP
rs1435774463 2264 dbSNP
rs57467543 2265 dbSNP
rs1379664086 2268 dbSNP
rs1244243531 2280 dbSNP
rs190469406 2281 dbSNP
rs1319772614 2284 dbSNP
rs1260969571 2294 dbSNP
rs1222836817 2295 dbSNP
rs565094052 2311 dbSNP
rs1368131413 2318 dbSNP
rs905535895 2324 dbSNP
rs781474291 2330 dbSNP
rs1334245222 2332 dbSNP
rs1330970187 2334 dbSNP
rs1038039294 2339 dbSNP
rs1402928962 2348 dbSNP
rs1174650796 2351 dbSNP
rs898273196 2356 dbSNP
rs994294030 2360 dbSNP
rs1173866903 2382 dbSNP
rs1270332547 2385 dbSNP
rs1436708293 2386 dbSNP
rs1047908842 2394 dbSNP
rs1178890153 2397 dbSNP
rs1458773426 2403 dbSNP
rs1239620139 2404 dbSNP
rs1459653309 2409 dbSNP
rs1209151129 2412 dbSNP
rs1182786429 2416 dbSNP
rs1280612079 2420 dbSNP
rs1221965226 2422 dbSNP
rs1348663972 2437 dbSNP
rs886566220 2438 dbSNP
rs1009110821 2450 dbSNP
rs1473761581 2455 dbSNP
rs1166070236 2456 dbSNP
rs1019187573 2465 dbSNP
rs1417535200 2470 dbSNP
rs1360286291 2482 dbSNP
rs1336749493 2484 dbSNP
rs964926677 2488 dbSNP
rs1379170247 2489 dbSNP
rs141926610 2491 dbSNP
rs544429034 2494 dbSNP
rs1382983427 2495 dbSNP
rs1450671427 2500 dbSNP
rs957491946 2501 dbSNP
rs989280202 2505 dbSNP
rs778425134 2513 dbSNP
rs1213580166 2515 dbSNP
rs1487885802 2517 dbSNP
rs1247696546 2518 dbSNP
rs749772043 2523 dbSNP
rs1285489577 2526 dbSNP
rs561356399 2530 dbSNP
rs529945966 2531 dbSNP
rs1356178168 2535 dbSNP
rs1313147989 2536 dbSNP
rs750159884 2541 dbSNP
rs971186656 2541 dbSNP
rs1268927822 2556 dbSNP
rs1339220449 2561 dbSNP
rs546793039 2568 dbSNP
rs1298331648 2573 dbSNP
rs1259370792 2575 dbSNP
rs1420954665 2576 dbSNP
rs1321015555 2579 dbSNP
rs1202610255 2580 dbSNP
rs927235179 2583 dbSNP
rs1423975229 2595 dbSNP
rs34341200 2597 dbSNP
rs560470495 2599 dbSNP
rs1184561014 2601 dbSNP
rs567183828 2608 dbSNP
rs1263782489 2612 dbSNP
rs532271391 2625 dbSNP
rs1489328880 2627 dbSNP
rs1038052667 2636 dbSNP
rs1221126974 2649 dbSNP
rs374292810 2651 dbSNP
rs929743622 2678 dbSNP
rs1047216060 2687 dbSNP
rs1340493978 2691 dbSNP
rs775482448 2696 dbSNP
rs1425830457 2700 dbSNP
rs527842667 2702 dbSNP
rs1402347720 2708 dbSNP
rs890869320 2712 dbSNP
rs1343112868 2714 dbSNP
rs1468478315 2718 dbSNP
rs1175956799 2728 dbSNP
rs749048078 2733 dbSNP
rs1398158487 2743 dbSNP
rs779027505 2746 dbSNP
rs1464878055 2748 dbSNP
rs1424017436 2749 dbSNP
rs1040499252 2751 dbSNP
rs1479381787 2753 dbSNP
rs1265363154 2769 dbSNP
rs900795015 2776 dbSNP
rs996358054 2780 dbSNP
rs1033034902 2781 dbSNP
rs1196940528 2788 dbSNP
rs1401105805 2791 dbSNP
rs1279591110 2803 dbSNP
rs957563541 2804 dbSNP
rs552158151 2806 dbSNP
rs1300068544 2810 dbSNP
rs1477028151 2820 dbSNP
rs568713231 2821 dbSNP
rs1020822516 2822 dbSNP
rs1369330360 2822 dbSNP
rs1328906252 2830 dbSNP
rs1346604938 2832 dbSNP
rs1445514334 2841 dbSNP
rs971469822 2845 dbSNP
rs1172467773 2852 dbSNP
rs537844004 2853 dbSNP
rs1203178728 2854 dbSNP
rs1172461555 2858 dbSNP
rs1309733547 2858 dbSNP
rs532015797 2858 dbSNP
rs56283756 2858 dbSNP
rs981295934 2858 dbSNP
rs1283236912 2869 dbSNP
rs1239243859 2871 dbSNP
rs1447553719 2873 dbSNP
rs1195725358 2874 dbSNP
rs1265499246 2875 dbSNP
rs1343556484 2881 dbSNP
rs1479493846 2885 dbSNP
rs927083476 2888 dbSNP
rs78136248 2890 dbSNP
rs1313459389 2893 dbSNP
rs1306378784 2898 dbSNP
rs1238980228 2902 dbSNP
rs974356659 2910 dbSNP
rs919609109 2914 dbSNP
rs929663988 2918 dbSNP
rs1157219538 2926 dbSNP
rs183044198 2933 dbSNP
rs1420891197 2952 dbSNP
rs1300574427 2953 dbSNP
rs1303380307 2957 dbSNP
rs1467470568 2963 dbSNP
rs912332380 2979 dbSNP
rs1156930906 2985 dbSNP
rs536471342 2988 dbSNP
rs1381131305 2989 dbSNP
rs1180948406 2995 dbSNP
rs1343175068 2998 dbSNP
rs943779677 3002 dbSNP
rs774868994 3003 dbSNP
rs1301290541 3004 dbSNP
rs900657569 3005 dbSNP
rs1332485202 3006 dbSNP
rs553117287 3015 dbSNP
rs1278788395 3018 dbSNP
rs1055084267 3024 dbSNP
rs1218787822 3030 dbSNP
rs766686644 3031 dbSNP
rs1339669757 3033 dbSNP
rs1313081681 3039 dbSNP
rs1289507483 3045 dbSNP
rs1358535184 3047 dbSNP
rs760477823 3050 dbSNP
rs866077415 3055 dbSNP
rs1361207102 3056 dbSNP
rs573493147 3057 dbSNP
rs866959505 3068 dbSNP
rs907299164 3073 dbSNP
rs1268090254 3075 dbSNP
rs1368254483 3077 dbSNP
rs1188671166 3081 dbSNP
rs776891408 3095 dbSNP
rs1179902959 3099 dbSNP
rs187055162 3115 dbSNP
rs559203164 3122 dbSNP
rs1207706645 3123 dbSNP
rs374331644 3123 dbSNP
rs958492066 3127 dbSNP
rs768373846 3134 dbSNP
rs544599688 3136 dbSNP
rs1424529843 3140 dbSNP
rs1027353821 3154 dbSNP
rs192732621 3155 dbSNP
rs1400477757 3157 dbSNP
rs982881907 3162 dbSNP
rs1320292631 3163 dbSNP
rs1392231613 3165 dbSNP
rs1403876214 3176 dbSNP
rs912202739 3182 dbSNP
rs868580797 3184 dbSNP
rs1389375510 3186 dbSNP
rs1463314322 3192 dbSNP
rs1421884504 3196 dbSNP
rs146294652 3214 dbSNP
rs776585304 3229 dbSNP
rs540442682 3230 dbSNP
rs1243413686 3236 dbSNP
rs1196119152 3238 dbSNP
rs1450734201 3239 dbSNP
rs1290111867 3242 dbSNP
rs1377096677 3252 dbSNP
rs1242064483 3264 dbSNP
rs1315865802 3267 dbSNP
rs975095545 3269 dbSNP
rs560347654 3270 dbSNP
rs1272057447 3273 dbSNP
rs1434369295 3278 dbSNP
rs1358675045 3296 dbSNP
rs1324492178 3298 dbSNP
rs570414848 3301 dbSNP
rs922113085 3302 dbSNP
rs1170406551 3304 dbSNP
rs534157866 3306 dbSNP
rs1266165369 3309 dbSNP
rs932176263 3314 dbSNP
rs1489500546 3316 dbSNP
rs532439851 3317 dbSNP
rs1422248126 3321 dbSNP
rs1054627999 3322 dbSNP
rs1237809737 3323 dbSNP
rs1458340384 3326 dbSNP
rs182754814 3327 dbSNP
rs562787052 3328 dbSNP
rs1383730054 3329 dbSNP
rs1423786306 3330 dbSNP
rs1199021044 3331 dbSNP
rs531236479 3337 dbSNP
rs1276378758 3352 dbSNP
rs764706277 3355 dbSNP
rs1344427391 3367 dbSNP
rs907163293 3370 dbSNP
rs1369762591 3372 dbSNP
rs772749731 3379 dbSNP
rs1297049877 3381 dbSNP
rs9055 3388 dbSNP
rs1447945816 3393 dbSNP
rs1356605251 3395 dbSNP
rs1338030163 3402 dbSNP
rs1448476682 3411 dbSNP
rs1334487422 3421 dbSNP
rs1332801217 3428 dbSNP
rs555861786 3430 dbSNP
rs1381746522 3431 dbSNP
rs1174966284 3435 dbSNP
rs1396598766 3438 dbSNP
rs995768958 3441 dbSNP
rs1379278303 3461 dbSNP
rs1179065042 3465 dbSNP
rs187782640 3481 dbSNP
rs1235472614 3483 dbSNP
rs1305631143 3484 dbSNP
rs951391195 3486 dbSNP
rs1225352828 3487 dbSNP
rs982699676 3489 dbSNP
rs1213084487 3494 dbSNP
rs1351837237 3508 dbSNP
rs1257452688 3513 dbSNP
rs1019244635 3515 dbSNP
rs756575199 3517 dbSNP
rs1200727035 3527 dbSNP
rs1448024507 3543 dbSNP
rs570907911 3547 dbSNP
rs921053940 3548 dbSNP
rs1182736897 3549 dbSNP
rs1417283855 3555 dbSNP
rs936415884 3578 dbSNP
rs28740801 3579 dbSNP
rs1420444434 3582 dbSNP
rs1411439987 3583 dbSNP
rs1427205008 3590 dbSNP
rs1169377007 3603 dbSNP
rs1423678080 3604 dbSNP
rs1043215 3605 dbSNP
rs1173801045 3609 dbSNP
rs1191369201 3611 dbSNP
rs1405173724 3611 dbSNP
rs1285320546 3617 dbSNP
rs946293619 3627 dbSNP
rs778925050 3630 dbSNP
rs1041956669 3632 dbSNP
rs1228088588 3639 dbSNP
rs1304316501 3642 dbSNP
rs928863800 3647 dbSNP
rs1398641782 3648 dbSNP
rs539216777 3655 dbSNP
rs1298270236 3662 dbSNP
rs1339293147 3662 dbSNP
rs1455075722 3668 dbSNP
rs559017822 3669 dbSNP
rs1163858401 3677 dbSNP
rs1405768998 3693 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cggagucucCGUCGACGAa 5'
                   | :||| || 
Target 5' ucuuauucuGGGGCUACUu 3'
 		3 - 21
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_001193508 | 3UTR | UUUUUCCUCUUUUCAGAGCUGCUUCUUAUUCUGGGGCUACUUUUUUUUUUAGUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_001193508 | 3UTR | UCAGAGCUGCUUCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_001193508 | 3UTR | UUCAGAGCUGCUUCUUAUUCUGGGGCUACUUUUUUUUUUAGUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_001193508 | 3UTR | UUCAGAGCUGCUUCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000309042.7 | 3UTR | CUUCUUAUUCUGGGGCUACUUUUUUUUUUA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.573 1.7e-3 0.457 1.2e-2 24 Click to see details
GSE28260 Renal cortex and medulla 0.657 7.3e-3 0.643 8.9e-3 13 Click to see details
GSE21687 Ependynoma primary tumors -0.214 4.5e-2 -0.234 3.1e-2 64 Click to see details
GSE38226 Liver fibrosis 0.232 1.6e-1 0.156 2.5e-1 21 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.225 1.7e-1 -0.095 3.5e-1 20 Click to see details
GSE42095 Differentiated embryonic stem cells -0.198 1.8e-1 -0.404 2.8e-2 23 Click to see details
GSE26953 Aortic valvular endothelial cells 0.127 2.8e-1 0.162 2.2e-1 24 Click to see details
GSE27834 Pluripotent stem cells 0.156 2.8e-1 0.224 2.0e-1 16 Click to see details
GSE17498 Multiple myeloma -0.088 2.9e-1 -0.003 4.9e-1 40 Click to see details
GSE14794 Lymphoblastoid cells -0.037 3.6e-1 -0.043 3.4e-1 90 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.058 3.9e-1 0.234 1.3e-1 25 Click to see details
GSE21849 B cell lymphoma -0.03 4.4e-1 0.003 4.9e-1 29 Click to see details
GSE17306 Multiple myeloma 0.008 4.8e-1 0.475 2.8e-4 49 Click to see details
GSE32688 Pancreatic cancer -0.01 4.8e-1 0.236 9.7e-2 32 Click to see details
GSE32688 Pancreatic cancer -0.01 4.8e-1 0.236 9.7e-2 32 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
243 hsa-miR-646 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061535 BTG2 BTG anti-proliferation factor 2 2 4
MIRT064692 CCND2 cyclin D2 2 4
MIRT068834 FNDC3A fibronectin type III domain containing 3A 2 10
MIRT079080 BIRC5 baculoviral IAP repeat containing 5 2 6
MIRT092735 SETD5 SET domain containing 5 2 4
MIRT093692 PI4K2B phosphatidylinositol 4-kinase type 2 beta 2 6
MIRT096244 CANX calnexin 2 2
MIRT096296 SQSTM1 sequestosome 1 2 4
MIRT098839 PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 2 2
MIRT100229 PRR3 proline rich 3 2 4
MIRT156479 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT186378 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT196460 TAOK1 TAO kinase 1 2 2
MIRT211252 FGF2 fibroblast growth factor 2 2 2
MIRT215233 NPM1 nucleophosmin 1 2 4
MIRT215383 CREBRF CREB3 regulatory factor 2 2
MIRT224972 BAG4 BCL2 associated athanogene 4 2 4
MIRT235598 KIF3B kinesin family member 3B 2 2
MIRT249860 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT258407 FOXK1 forkhead box K1 2 2
MIRT269359 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT310455 REST RE1 silencing transcription factor 2 2
MIRT314057 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 2 8
MIRT322288 SLC39A14 solute carrier family 39 member 14 2 2
MIRT326311 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT329703 SCD stearoyl-CoA desaturase 2 2
MIRT341278 PABPN1 poly(A) binding protein nuclear 1 2 3
MIRT403798 AKIRIN1 akirin 1 2 2
MIRT438549 NOB1 NIN1/PSMD8 binding protein 1 homolog 1 1
MIRT441908 SEPN1 selenoprotein N 2 2
MIRT444125 ZNRF3 zinc and ring finger 3 2 2
MIRT445458 EXT1 exostosin glycosyltransferase 1 2 4
MIRT446500 ASCC1 activating signal cointegrator 1 complex subunit 1 2 2
MIRT446538 GOLGA8B golgin A8 family member B 2 2
MIRT447770 DMRT2 doublesex and mab-3 related transcription factor 2 2 2
MIRT448438 TLL1 tolloid like 1 2 2
MIRT448768 GOLGA8A golgin A8 family member A 2 2
MIRT460749 SRP14 signal recognition particle 14 2 2
MIRT461556 ACTR3B ARP3 actin related protein 3 homolog B 2 2
MIRT463163 ZNF367 zinc finger protein 367 2 10
MIRT464234 VEGFA vascular endothelial growth factor A 5 12
MIRT464496 UCK2 uridine-cytidine kinase 2 2 2
MIRT465157 TSC22D2 TSC22 domain family member 2 2 2
MIRT466429 TFAP2A transcription factor AP-2 alpha 2 8
MIRT467395 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT468672 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT469407 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT470750 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT471947 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT472468 NAPG NSF attachment protein gamma 2 12
MIRT474571 KLHDC3 kelch domain containing 3 2 2
MIRT477443 ELOVL5 ELOVL fatty acid elongase 5 2 2
MIRT480541 BZW1 basic leucine zipper and W2 domains 1 2 12
MIRT482110 AKT3 AKT serine/threonine kinase 3 2 4
MIRT485206 PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha 2 8
MIRT492318 SETD1B SET domain containing 1B 2 4
MIRT497144 TAPBP TAP binding protein 2 2
MIRT498976 ORC4 origin recognition complex subunit 4 2 8
MIRT499112 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 8
MIRT499448 ODF2L outer dense fiber of sperm tails 2 like 2 8
MIRT500089 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 8
MIRT500317 ZNF622 zinc finger protein 622 2 8
MIRT500414 ZMAT3 zinc finger matrin-type 3 2 8
MIRT500572 USP53 ubiquitin specific peptidase 53 2 2
MIRT500596 UBN2 ubinuclein 2 2 10
MIRT500797 TLK1 tousled like kinase 1 2 8
MIRT500932 SRPR SRP receptor alpha subunit 2 6
MIRT500946 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 2 8
MIRT501081 SMAD7 SMAD family member 7 2 8
MIRT501515 PPTC7 PTC7 protein phosphatase homolog 2 6
MIRT501879 MOB4 MOB family member 4, phocein 2 8
MIRT502195 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT502630 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT502650 DCTN5 dynactin subunit 5 2 8
MIRT502914 CDCA4 cell division cycle associated 4 2 8
MIRT502938 CDC37L1 cell division cycle 37 like 1 2 8
MIRT502987 CCND1 cyclin D1 6 3
MIRT503181 AGO2 argonaute 2, RISC catalytic component 2 6
MIRT504532 ZNF620 zinc finger protein 620 2 6
MIRT504715 DLC1 DLC1 Rho GTPase activating protein 2 6
MIRT504967 ZNRF2 zinc and ring finger 2 2 2
MIRT505073 ZFHX4 zinc finger homeobox 4 2 6
MIRT505109 YTHDC1 YTH domain containing 1 2 6
MIRT505342 TMEM245 transmembrane protein 245 2 6
MIRT505389 TMEM100 transmembrane protein 100 2 2
MIRT505681 SESTD1 SEC14 and spectrin domain containing 1 2 6
MIRT506162 PLAG1 PLAG1 zinc finger 2 8
MIRT506185 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 6
MIRT506354 NUP50 nucleoporin 50 2 6
MIRT506480 MYO5A myosin VA 2 6
MIRT506833 KIF23 kinesin family member 23 2 6
MIRT507310 FEM1B fem-1 homolog B 2 4
MIRT507847 CCNE2 cyclin E2 2 6
MIRT508670 DIABLO diablo IAP-binding mitochondrial protein 2 4
MIRT509137 ZNF691 zinc finger protein 691 2 4
MIRT509686 ATAD5 ATPase family, AAA domain containing 5 2 4
MIRT512205 C1orf21 chromosome 1 open reading frame 21 2 6
MIRT518087 TRIM35 tripartite motif containing 35 2 2
MIRT518990 NNT nicotinamide nucleotide transhydrogenase 2 4
MIRT520964 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT521049 SLC2A3 solute carrier family 2 member 3 2 4
MIRT521192 SBNO1 strawberry notch homolog 1 2 6
MIRT521619 PSAT1 phosphoserine aminotransferase 1 2 6
MIRT522770 LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 2 2
MIRT533754 TMEM184B transmembrane protein 184B 2 2
MIRT534131 SNTB2 syntrophin beta 2 2 4
MIRT537159 GID8 GID complex subunit 8 homolog 2 2
MIRT537812 EFNB2 ephrin B2 2 4
MIRT538108 DDX6 DEAD-box helicase 6 2 2
MIRT540839 GNAT1 G protein subunit alpha transducin 1 2 4
MIRT541019 WIPI2 WD repeat domain, phosphoinositide interacting 2 2 2
MIRT541145 PISD phosphatidylserine decarboxylase 2 2
MIRT541387 CDC42SE2 CDC42 small effector 2 2 2
MIRT541422 CBX4 chromobox 4 2 2
MIRT543521 PRSS21 protease, serine 21 2 2
MIRT543794 RALGAPB Ral GTPase activating protein non-catalytic beta subunit 2 4
MIRT543831 GSG1 germ cell associated 1 2 2
MIRT544961 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT545182 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 4
MIRT545343 CCDC83 coiled-coil domain containing 83 2 2
MIRT545367 LIN7C lin-7 homolog C, crumbs cell polarity complex component 2 2
MIRT545656 SPARC secreted protein acidic and cysteine rich 2 2
MIRT545678 DECR1 2,4-dienoyl-CoA reductase 1 2 2
MIRT545938 ZBTB44 zinc finger and BTB domain containing 44 2 4
MIRT546107 USP48 ubiquitin specific peptidase 48 2 4
MIRT546603 SALL1 spalt like transcription factor 1 2 4
MIRT546628 RTN4 reticulon 4 2 2
MIRT547321 NPTN neuroplastin 2 2
MIRT547660 KPNA3 karyopherin subunit alpha 3 2 2
MIRT547994 HCFC2 host cell factor C2 2 4
MIRT548048 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548098 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 4
MIRT548721 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT548938 CDK17 cyclin dependent kinase 17 2 2
MIRT549071 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT549272 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT549438 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT550462 OSCAR osteoclast associated, immunoglobulin-like receptor 2 4
MIRT550794 WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 2 2
MIRT550819 FAM229B family with sequence similarity 229 member B 2 2
MIRT551537 EMB embigin 2 2
MIRT552031 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552340 ZNF704 zinc finger protein 704 2 2
MIRT552444 ZNF449 zinc finger protein 449 2 2
MIRT553116 UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 2
MIRT553448 TOX4 TOX high mobility group box family member 4 2 2
MIRT553725 TBX18 T-box 18 2 2
MIRT553805 SZRD1 SUZ RNA binding domain containing 1 2 4
MIRT554696 RNF149 ring finger protein 149 2 2
MIRT554831 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT555139 PTPRD protein tyrosine phosphatase, receptor type D 2 2
MIRT555269 PRDM4 PR/SET domain 4 2 2
MIRT555312 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 4
MIRT555558 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT556379 LURAP1L leucine rich adaptor protein 1 like 2 2
MIRT556669 KMT2D lysine methyltransferase 2D 2 4
MIRT556853 KANK1 KN motif and ankyrin repeat domains 1 2 4
MIRT557476 GPR27 G protein-coupled receptor 27 2 4
MIRT558361 DMTF1 cyclin D binding myb like transcription factor 1 2 2
MIRT558385 DHX33 DEAH-box helicase 33 2 2
MIRT558502 CYP26B1 cytochrome P450 family 26 subfamily B member 1 2 4
MIRT558515 CTDSPL CTD small phosphatase like 2 4
MIRT558583 CREBL2 cAMP responsive element binding protein like 2 2 4
MIRT558641 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT558653 CNKSR3 CNKSR family member 3 2 2
MIRT558865 CD2AP CD2 associated protein 2 2
MIRT558888 CCNE1 cyclin E1 2 4
MIRT559002 CA8 carbonic anhydrase 8 2 2
MIRT559149 BTN3A3 butyrophilin subfamily 3 member A3 2 2
MIRT559999 RAB3IP RAB3A interacting protein 2 2
MIRT562023 LANCL1 LanC like 1 2 2
MIRT562474 CNOT6L CCR4-NOT transcription complex subunit 6 like 2 2
MIRT562586 CBX2 chromobox 2 2 2
MIRT562595 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT562873 KIAA1456 KIAA1456 2 2
MIRT562989 KIAA0408 KIAA0408 2 4
MIRT563082 SLC25A12 solute carrier family 25 member 12 2 2
MIRT563499 DLGAP3 DLG associated protein 3 2 2
MIRT563892 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT564328 CCNT1 cyclin T1 2 2
MIRT564945 XKR7 XK related 7 2 2
MIRT564981 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT566302 PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A 2 2
MIRT566701 MTMR3 myotubularin related protein 3 2 2
MIRT566827 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 2
MIRT571236 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT571424 RIF1 replication timing regulatory factor 1 2 2
MIRT571637 SKI SKI proto-oncogene 2 2
MIRT571836 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT571962 KIF5B kinesin family member 5B 2 2
MIRT572104 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT572183 CDK6 cyclin dependent kinase 6 2 2
MIRT572720 RBL1 RB transcriptional corepressor like 1 2 2
MIRT574589 N4BP1 NEDD4 binding protein 1 2 2
MIRT575878 Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2 3
MIRT609979 HERPUD2 HERPUD family member 2 2 2
MIRT612932 GPRIN3 GPRIN family member 3 2 2
MIRT614327 C1orf220 chromosome 1 open reading frame 220 2 2
MIRT614694 TRAK1 trafficking kinesin protein 1 2 2
MIRT618328 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT618456 ZFP30 ZFP30 zinc finger protein 2 4
MIRT621135 EMC7 ER membrane protein complex subunit 7 2 4
MIRT622878 PDE12 phosphodiesterase 12 2 4
MIRT631163 CCBE1 collagen and calcium binding EGF domains 1 2 2
MIRT632793 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT636731 AFAP1 actin filament associated protein 1 2 2
MIRT649297 IRF8 interferon regulatory factor 8 2 2
MIRT650955 QPCTL glutaminyl-peptide cyclotransferase like 2 2
MIRT653267 SOGA3 SOGA family member 3 2 2
MIRT654665 PSMG1 proteasome assembly chaperone 1 2 2
MIRT656180 MPRIP myosin phosphatase Rho interacting protein 2 2
MIRT659252 CUL3 cullin 3 2 2
MIRT663826 NLRP12 NLR family pyrin domain containing 12 2 4
MIRT676632 CSNK1E casein kinase 1 epsilon 2 2
MIRT679503 ZNF106 zinc finger protein 106 2 2
MIRT680978 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT682272 RS1 retinoschisin 1 2 2
MIRT682421 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT682510 GLP2R glucagon like peptide 2 receptor 2 2
MIRT693926 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT700660 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT700740 PLEKHA8 pleckstrin homology domain containing A8 2 2
MIRT702871 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT703192 GPBP1 GC-rich promoter binding protein 1 2 2
MIRT704453 CSNK2A1 casein kinase 2 alpha 1 2 2
MIRT704709 CHEK1 checkpoint kinase 1 2 2
MIRT706164 CASK calcium/calmodulin dependent serine protein kinase 2 3
MIRT713334 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT713416 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT716300 PAX1 paired box 1 2 2
MIRT717394 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT718453 BTNL9 butyrophilin like 9 2 2
MIRT718728 VWA9 integrator complex subunit 14 2 2
MIRT719029 SHROOM3 shroom family member 3 2 2
MIRT720367 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT723120 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT733741 EGFR epidermal growth factor receptor 4 0
MIRT734281 HIF1A hypoxia inducible factor 1 alpha subunit 3 0
MIRT735934 EYA3 EYA transcriptional coactivator and phosphatase 3 3 0
MIRT755830 IGF1 insulin like growth factor 1 5 1
MIRT755831 BCL2 BCL2, apoptosis regulator 4 1
MIRT755832 CDK2 cyclin dependent kinase 2 4 1
MIRT755833 BAX BCL2 associated X, apoptosis regulator 4 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-646 Fluorouracil 3385 NSC19893 approved resistant cell line (OE19)
hsa-miR-646 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-646 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM43)
hsa-miR-646 Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-646 Oxaliplatin 6857599 NSC266046 approved sensitive cell line (IGROV-1)
hsa-miR-646 Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-646 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-646 Cisplatin 5460033 NSC119875 approved sensitive cell line (H460)

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