miRTarBase - #MIRT322288


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pre-miRNA Information
pre-miRNA hsa-mir-646   
Genomic Coordinates chr20: 60308474 - 60308567
Synonyms MIRN646, hsa-mir-646, MIR646
Description Homo sapiens miR-646 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-646
Sequence 61| AAGCAGCUGCCUCUGAGGC |79
Evidence Experimental
Experiments SAGE
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs750684400 6 dbSNP
rs112880289 10 dbSNP
rs553679341 11 dbSNP
rs941692683 13 dbSNP
rs6513497 14 dbSNP
rs1431341059 18 dbSNP
rs1479355932 19 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SLC39A14   
Synonyms HMNDYT2, LZT-Hs4, NET34, ZIP14, cig19
Description solute carrier family 39 member 14
Transcript NM_001128431   
Other Transcripts NM_001135153 , NM_001135154 , NM_015359   
Expression
Putative miRNA Targets on SLC39A14
3'UTR of SLC39A14
(miRNA target sites are highlighted)		 
>SLC39A14|NM_001128431|3'UTR
   1 GGCTCTGCCAAGAGCCTGTGGGACTGGAAGTCGGGCCCTGGGCTGCCCGATCGCCAGCCCGAGGACTTACCATCCACAAT
  81 GCACCACGGAAGAGGCCGTTCTATGAAAAACTGACACAGACTGTATTCCTGCATTCAAATGTCAGCCGTTTGTAAAATGC
 161 TGTATCCTAGGAATAAGCTGCCCTGGTAACCAGTCTCTAGCTAGTGCCTCTTGCCCTCTCCTCACCTCCTTTTCTCTCAG
 241 TGACTCTGGAACCTGAATGCAGCTTACAAGACAAGCCTGACTTTTTTCTCTGATTACCTTGGCCTCCTCTTGGAACCAGT
 321 GCTGAAAGGTTTTGAATCCTTTACCCAACAATGCAAAAATAGAGCCAATGGTTATAACTTGGCTAGAAATATCAAGAGTT
 401 GAATCCATAGTGTGGGGCCCATGACTCTAGCTGGGCACCTTGGACCTCCAGCTGGCCAATAGAAGAGACAGGAGACAGGA
 481 AGCCTTCCCATTTTTTCAAAGTCTGTTTAATTGCCTATTACTTCTCTCAAAGAGAACCTGAAGTCAGAACACATGAGCAG
 561 GGTGAGAGGTGAGGCAAGGTTCATCCTGAATGGGAGAGGAAGTCGAACCACTGCTGTGTGTCTTGTCAGGATGCTCACTT
 641 GTTCCTACTGAGATGCTGGATATTGATTTTGTAACAGCACCTGGTGTTTCACGGCTGTCCGAGTGAGCTAACGTGGCGGT
 721 GTGGCTGCCTGGACCTCCTCTTTCAGGTTAACGCTGACAGAATGGAGGCTCAGGCTGTCTGCAAGAAAACAGTTGGTTTG
 801 GCTGTGATTTTGACCTCCTCTTCCCCACTGCCATCTTCTAAGAGACTTTGTAGCTGCCTCCTAGAAGCACATTCTGAGCA
 881 CATTTGAGACCTCTGTGTTAGAGGGGAGACTGCACAAACTATCCTCCCCCAGGTTGAGACGTCTGCAGAGTGGCAAGCTG
 961 ACTTGTAGAAATGGGGTGCCATTTATGCTCTACTTAGACAAGGGTAATCAGAAATGGAATCAGTGCAGGCAAAATTTAGG
1041 ATTTGCCGCTTCCATAAATCAAAGCATGACTAATAGGGGGTCTCTGAAATGTAAGGGCACAAACTTCACTTAGGGCATCG
1121 CAGATGTTTGCAGAATGGTTGGCCTAATGATTATGCTACAGATGGGTTTTAAATGACCCGTCTAGGTTACTGCTTCCTTG
1201 CAAAAAAAGTCGAATCCTGCATTGAATTGAATATGAATTTCTCTAACTCTCTCCAGAAAATGGATGGAGATAACTTGTCT
1281 TTAAAACTGTAGGCCAGCCTTAGCCACTGTGGAGCCCTTGCCTCCGAGCTCTGGCTTCAAGGGGAGCTCTTCTCCAGGTT
1361 CACTAGGTGAATTGATTTATTATTATCATATTGATAATGTGAGATTCTTTAGCCACTTTGGGGAGCCTGTCTCTCCAGAA
1441 GCCTTTCTTAGTGGTGCCCACAGTTGGAGCCCAGGGGCCATGTTTGCAAACTGATTCATGTGCATGGCTGACAGGAGTAC
1521 TGGTTCACTACCAATGCCTGAGCTTTTCTCTTACATAGAAAAACTGTCCGCTCTCAGTAATCACAAGCAGCATCCGTTTT
1601 GTTTTCTCTTCTTGGGAGACATCTGTCAAACCAGGAATATTCTTGAAAAGAACGTGAGCAGGAAAAACTGCTGGTGATAC
1681 TTTTTTTAAGTTTTGTTTTTATCTTGCCTGTTGGCTTCAATACATTTGAGAATACGCTGAAGAGGGAAAATTTCAGTGAT
1761 GGAGATTCTAGATTAAATATCAGGACTGATTTCCTGGTGGGATTATGGTCCAGTTTTACCAAAGAACCAATTCCTTGAAT
1841 GTTGGAATCTAACTTTTTATATTGTCATTATTATTGTTGTTTTTAAACGGTTCTTTGTCTTTTCTGTTTTATTTTTCTCA
1921 AGCTGCTTTCAGGAGCTAGCAGAAAATAACTCAAAGTTGAAGACTCTGGAAGATTTTGCTTTAACCTAACTCGCATTGAT
2001 GTATTAAATTTATAATTTTAGCATTCCCAATAGATCCTATCATTCCTTAAACATAATACCCTTTGTCTTGGAGTAGAATA
2081 CTAAGTTAGAGTTAGTGGATTTCTAGTTTAGGAGAGGAGCTCAAAACTATAATCTTTAACAAATTGAAAAATGAAATAGG
2161 GTGTTTTCCCTTTTTGTGCACACCTATATTACCTTAAGAAATTTCCTTCCATAGACAGCTGCCTCAAAGGGAAATCCTCT
2241 TTAAACCGTAGTTGGCGCAGAGGTCAGTCCTAGTCGGAGCTTAGGAGGGGCGGAGACGCTCACATCGTCTGACTTGAGTC
2321 GCCACTGATTGTGGCAACAGCTTTGCCTCATGAGTCAAAAATTGGCAATTTCTTTTGATTTTTAGTTGTTGAATTTGCTG
2401 TTTCAAGCATTTGTACATATTAGAAGTCTAAGGAGTAGCAAGTCAGTGGGAGGACTTTTTCACCCCTGGCATTAGCAGCT
2481 TCGACCTCATTTTCCAGATGCACCAGCTCCTATTAATAAGTTAGCAAGGAAAGTGTATGTCACGTGCAGGAACAGTGAGG
2561 CAGGGACAGGGGTTCTGCTCCTTCTCACTTCACCACCGGCACACAGCTTGCCCCTGTCTTTGCCCCCAAAGGTATTTTGT
2641 GTCTAGTGTCAAATTGGAGCTATTCTTCACTGGTCCTTAACCTTGGGTTTTAAAAAGAAGGCTTCTCTGTTTGGGTAGCG
2721 TAAGAGCTGAGTATAGTAAGTCCTCTTCCAAAGAGATGGCAATATGCTGGGCATCTACTTTAAAACAAAGTTGTCTGATT
2801 TTTGCAAGAGAGGTTAGGATTTTATTGTTCTTATTTCCCTTTACAGTTCTGCAGTTCCATCACAGTATTTTTTTAAATAA
2881 CTCAGGTGTATGAGAAGAAATTAGAAAAGAAAATTAACTTATGTGGACTGTAAATGTTTTATTTGTAAGATTCTATAAAT
2961 AAAGCTATATTCTGTAATTGTTGAGAATCCCACGGGTGATCATTTGCAATAAATGTGGATGTAATGAAGGCTGTTGAAAA
3041 AAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgGAGUCUCCGUCGACGAa 5'
            ||||     ||||||| 
Target 5' ttCTCA-----AGCTGCTt 3'
 1915 - 1928 144.00 -13.10
2 
miRNA  3' cggaGUCUCCGUCGACGaa 5'
              || || |||||||  
Target 5' cttcCATAGACAGCTGCct 3'
 2206 - 2224 139.00 -15.20
3 
miRNA  3' cgGAGUCUC-----CGUCGACGaa 5'
            || ||||     |:||||||  
Target 5' ttCTAAGAGACTTTGTAGCTGCct 3'
 836 - 859 137.00 -15.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM1456095 1 COSMIC
COSM4527637 1 COSMIC
COSN30187779 8 COSMIC
COSN31524500 17 COSMIC
COSN8518717 50 COSMIC
COSN31582156 53 COSMIC
COSN31539355 54 COSMIC
COSN31587621 62 COSMIC
COSN30498563 98 COSMIC
COSN31596213 133 COSMIC
COSN31546214 147 COSMIC
COSN31597241 165 COSMIC
COSN1362717 299 COSMIC
COSN22357312 416 COSMIC
COSN6919338 643 COSMIC
COSN2269764 968 COSMIC
COSN23046509 1037 COSMIC
COSN23245400 1102 COSMIC
COSN23441255 1105 COSMIC
COSN31571674 1242 COSMIC
COSN31537809 1247 COSMIC
COSN31516793 1446 COSMIC
COSN28676130 1571 COSMIC
COSN31606740 1619 COSMIC
COSN30169881 1765 COSMIC
COSN20105269 1803 COSMIC
COSN8077401 1887 COSMIC
COSN31568195 1912 COSMIC
COSN5110726 1947 COSMIC
COSN21456978 2378 COSMIC
COSN28649855 2606 COSMIC
COSN23987470 2639 COSMIC
COSN28671664 2653 COSMIC
COSN31570710 2720 COSMIC
COSN6919339 2840 COSMIC
COSN29689716 2855 COSMIC
COSN7669466 3020 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs753135541 6 dbSNP
rs756699269 8 dbSNP
rs1437347085 9 dbSNP
rs777974202 16 dbSNP
rs1416147932 18 dbSNP
rs1334205807 20 dbSNP
rs1325370249 23 dbSNP
rs1428145684 24 dbSNP
rs757721551 30 dbSNP
rs779800125 31 dbSNP
rs986234952 32 dbSNP
rs1340817704 33 dbSNP
rs554639966 34 dbSNP
rs1177301174 35 dbSNP
rs199981799 36 dbSNP
rs776263160 41 dbSNP
rs1201552949 45 dbSNP
rs748015573 49 dbSNP
rs946151964 50 dbSNP
rs769811034 51 dbSNP
rs375980222 53 dbSNP
rs180878892 54 dbSNP
rs780465988 61 dbSNP
rs1426925642 62 dbSNP
rs1164242300 64 dbSNP
rs902351392 65 dbSNP
rs1003347155 67 dbSNP
rs780216648 69 dbSNP
rs553245263 71 dbSNP
rs1330912034 75 dbSNP
rs797017124 80 dbSNP
rs1446258000 83 dbSNP
rs1011947909 84 dbSNP
rs1434187963 85 dbSNP
rs906726418 86 dbSNP
rs938153060 87 dbSNP
rs1027312911 89 dbSNP
rs1246431239 95 dbSNP
rs553184339 98 dbSNP
rs888183792 99 dbSNP
rs1005668739 102 dbSNP
rs577829780 104 dbSNP
rs1197484557 108 dbSNP
rs1015253327 109 dbSNP
rs1188491793 118 dbSNP
rs1463932934 148 dbSNP
rs1004637086 149 dbSNP
rs747392464 152 dbSNP
rs1015060674 153 dbSNP
rs1273043662 162 dbSNP
rs1456951122 167 dbSNP
rs1288745536 174 dbSNP
rs753977933 184 dbSNP
rs139424083 202 dbSNP
rs545264481 202 dbSNP
rs966201551 207 dbSNP
rs142071782 211 dbSNP
rs1362913907 216 dbSNP
rs953875147 217 dbSNP
rs985280543 218 dbSNP
rs922216221 221 dbSNP
rs953625195 225 dbSNP
rs118043727 236 dbSNP
rs914583018 239 dbSNP
rs946005965 240 dbSNP
rs913904145 245 dbSNP
rs1168340758 270 dbSNP
rs1368268092 271 dbSNP
rs868356337 272 dbSNP
rs1472058277 276 dbSNP
rs1187575431 291 dbSNP
rs542749573 291 dbSNP
rs1170171644 294 dbSNP
rs1475471250 302 dbSNP
rs1245569555 303 dbSNP
rs1219011051 304 dbSNP
rs560926432 305 dbSNP
rs966657031 310 dbSNP
rs1292288802 321 dbSNP
rs982340695 330 dbSNP
rs145726803 346 dbSNP
rs546591214 361 dbSNP
rs939187736 365 dbSNP
rs185773087 370 dbSNP
rs190000389 389 dbSNP
rs1273149538 394 dbSNP
rs1438949094 399 dbSNP
rs1333180810 409 dbSNP
rs1338513863 410 dbSNP
rs895096720 416 dbSNP
rs1012166857 420 dbSNP
rs1428260168 422 dbSNP
rs1270678434 425 dbSNP
rs909656616 428 dbSNP
rs1049409825 432 dbSNP
rs551245753 437 dbSNP
rs1414392393 440 dbSNP
rs1423921966 442 dbSNP
rs747604232 445 dbSNP
rs1264525183 450 dbSNP
rs569395521 456 dbSNP
rs1461446113 457 dbSNP
rs1014700762 458 dbSNP
rs1269191023 461 dbSNP
rs1180942629 467 dbSNP
rs1481957890 471 dbSNP
rs1252780423 481 dbSNP
rs76963096 493 dbSNP
rs896837162 494 dbSNP
rs1051039409 498 dbSNP
rs997822732 498 dbSNP
rs1346188828 499 dbSNP
rs1441026718 518 dbSNP
rs889691116 518 dbSNP
rs1006769597 523 dbSNP
rs997676228 539 dbSNP
rs1477812700 554 dbSNP
rs1466018942 558 dbSNP
rs957392476 559 dbSNP
rs1168549622 561 dbSNP
rs1178816122 571 dbSNP
rs1470681591 572 dbSNP
rs1429307380 585 dbSNP
rs1021427120 595 dbSNP
rs111797091 605 dbSNP
rs950900356 606 dbSNP
rs966711028 609 dbSNP
rs772634257 617 dbSNP
rs563489169 618 dbSNP
rs1324391143 619 dbSNP
rs1267516395 624 dbSNP
rs1226852232 631 dbSNP
rs1318932040 635 dbSNP
rs867902380 645 dbSNP
rs1308206852 648 dbSNP
rs1395838300 655 dbSNP
rs747871478 658 dbSNP
rs566589554 672 dbSNP
rs1051631 683 dbSNP
rs1339282818 689 dbSNP
rs1453925886 691 dbSNP
rs115363319 692 dbSNP
rs967421897 693 dbSNP
rs181219788 694 dbSNP
rs928761920 698 dbSNP
rs17060854 701 dbSNP
rs910055584 702 dbSNP
rs992032238 709 dbSNP
rs1461712994 713 dbSNP
rs916419065 713 dbSNP
rs73227843 714 dbSNP
rs933670888 717 dbSNP
rs1261548252 718 dbSNP
rs575522321 719 dbSNP
rs542810614 721 dbSNP
rs889743467 732 dbSNP
rs1365074167 734 dbSNP
rs554727325 736 dbSNP
rs1352479424 752 dbSNP
rs573004578 753 dbSNP
rs940397545 754 dbSNP
rs1363560832 763 dbSNP
rs1264362662 771 dbSNP
rs1165210422 778 dbSNP
rs1488210288 791 dbSNP
rs1192161965 797 dbSNP
rs1271074331 808 dbSNP
rs892980783 808 dbSNP
rs1209538350 814 dbSNP
rs1433826632 814 dbSNP
rs1487619975 821 dbSNP
rs866463718 826 dbSNP
rs1010470082 840 dbSNP
rs1021061561 842 dbSNP
rs1341850003 867 dbSNP
rs966762521 870 dbSNP
rs1455594192 879 dbSNP
rs1327690346 880 dbSNP
rs561391355 888 dbSNP
rs1158966812 892 dbSNP
rs1003532966 903 dbSNP
rs879752495 905 dbSNP
rs540308082 912 dbSNP
rs1343216659 914 dbSNP
rs1034991590 916 dbSNP
rs1425104086 917 dbSNP
rs901642282 918 dbSNP
rs1417744632 922 dbSNP
rs959327606 927 dbSNP
rs997225870 929 dbSNP
rs1373786016 935 dbSNP
rs1198212425 940 dbSNP
rs1017575532 941 dbSNP
rs1368264893 942 dbSNP
rs1028667103 944 dbSNP
rs1479606863 949 dbSNP
rs1271346308 951 dbSNP
rs889297387 966 dbSNP
rs528626118 967 dbSNP
rs564768266 972 dbSNP
rs1198137347 974 dbSNP
rs1012134316 977 dbSNP
rs1340668103 991 dbSNP
rs1021899700 992 dbSNP
rs1251439441 993 dbSNP
rs973295040 994 dbSNP
rs968019249 1000 dbSNP
rs1287137819 1002 dbSNP
rs977482751 1005 dbSNP
rs187079768 1010 dbSNP
rs1353462658 1018 dbSNP
rs867169404 1043 dbSNP
rs1214966489 1046 dbSNP
rs1405119037 1048 dbSNP
rs1035689154 1049 dbSNP
rs959989522 1050 dbSNP
rs1393108270 1052 dbSNP
rs918380555 1055 dbSNP
rs933721792 1073 dbSNP
rs796335349 1075 dbSNP
rs991578096 1075 dbSNP
rs1468327135 1086 dbSNP
rs1431451671 1089 dbSNP
rs915974561 1091 dbSNP
rs1177433319 1092 dbSNP
rs1293373741 1105 dbSNP
rs947937739 1117 dbSNP
rs985016992 1118 dbSNP
rs1265380462 1119 dbSNP
rs116076348 1120 dbSNP
rs544582186 1121 dbSNP
rs1256111849 1122 dbSNP
rs1199179487 1129 dbSNP
rs3735896 1140 dbSNP
rs190721332 1142 dbSNP
rs932961096 1149 dbSNP
rs893024176 1153 dbSNP
rs1050149879 1155 dbSNP
rs770313236 1161 dbSNP
rs1240943302 1164 dbSNP
rs907010021 1180 dbSNP
rs1457355401 1181 dbSNP
rs1011773580 1183 dbSNP
rs1408460392 1186 dbSNP
rs1337459872 1194 dbSNP
rs1291220526 1201 dbSNP
rs1398045830 1202 dbSNP
rs1406096777 1202 dbSNP
rs1160475814 1207 dbSNP
rs375527002 1208 dbSNP
rs1308043622 1209 dbSNP
rs1035045644 1212 dbSNP
rs550485867 1213 dbSNP
rs527813675 1221 dbSNP
rs1374252644 1228 dbSNP
rs1238430544 1241 dbSNP
rs1039687002 1246 dbSNP
rs1315347554 1247 dbSNP
rs1035909372 1250 dbSNP
rs559629812 1254 dbSNP
rs1445867379 1268 dbSNP
rs1281740604 1269 dbSNP
rs960040205 1270 dbSNP
rs1017211380 1271 dbSNP
rs79192938 1290 dbSNP
rs777015936 1292 dbSNP
rs568852183 1307 dbSNP
rs1243768115 1308 dbSNP
rs1263719033 1313 dbSNP
rs1459161942 1316 dbSNP
rs1025827936 1323 dbSNP
rs141830169 1326 dbSNP
rs1237795843 1327 dbSNP
rs952899057 1329 dbSNP
rs1390550535 1335 dbSNP
rs1438129201 1336 dbSNP
rs984680675 1338 dbSNP
rs909043545 1339 dbSNP
rs1386435691 1343 dbSNP
rs34341867 1354 dbSNP
rs1188441659 1364 dbSNP
rs1474797276 1365 dbSNP
rs910958515 1366 dbSNP
rs551658917 1368 dbSNP
rs1447209959 1380 dbSNP
rs990219801 1386 dbSNP
rs1423129923 1387 dbSNP
rs971969438 1388 dbSNP
rs1162621340 1391 dbSNP
rs923169177 1392 dbSNP
rs933009960 1394 dbSNP
rs1374768572 1395 dbSNP
rs1465658483 1396 dbSNP
rs1330182621 1397 dbSNP
rs1431803157 1399 dbSNP
rs1330719848 1410 dbSNP
rs116267324 1413 dbSNP
rs569145685 1419 dbSNP
rs1366512490 1420 dbSNP
rs910333871 1421 dbSNP
rs536529055 1426 dbSNP
rs1042774014 1438 dbSNP
rs903357395 1443 dbSNP
rs895203288 1447 dbSNP
rs1012290631 1459 dbSNP
rs1292216515 1464 dbSNP
rs1017343444 1470 dbSNP
rs898463189 1477 dbSNP
rs1380390919 1481 dbSNP
rs1215264004 1492 dbSNP
rs994438088 1498 dbSNP
rs554839751 1503 dbSNP
rs999004087 1504 dbSNP
rs1406933106 1513 dbSNP
rs1057410735 1514 dbSNP
rs1311180489 1517 dbSNP
rs1320672308 1520 dbSNP
rs1025870795 1523 dbSNP
rs1356760996 1529 dbSNP
rs1171671695 1532 dbSNP
rs1219311424 1535 dbSNP
rs1427923965 1544 dbSNP
rs1173887817 1554 dbSNP
rs1257519031 1556 dbSNP
rs1269385047 1560 dbSNP
rs955550869 1562 dbSNP
rs80097761 1570 dbSNP
rs1051638 1571 dbSNP
rs1022969977 1574 dbSNP
rs952706878 1581 dbSNP
rs150491604 1585 dbSNP
rs1225651626 1592 dbSNP
rs138265470 1595 dbSNP
rs967047160 1596 dbSNP
rs769558518 1597 dbSNP
rs766813121 1607 dbSNP
rs1375924724 1613 dbSNP
rs962206764 1614 dbSNP
rs576773111 1619 dbSNP
rs1421570488 1620 dbSNP
rs1478142875 1622 dbSNP
rs1452535680 1624 dbSNP
rs751887642 1626 dbSNP
rs1334086642 1633 dbSNP
rs1470780593 1637 dbSNP
rs1429586426 1642 dbSNP
rs544158580 1644 dbSNP
rs1417087635 1645 dbSNP
rs1409813982 1654 dbSNP
rs1177769654 1655 dbSNP
rs562862161 1657 dbSNP
rs1443925809 1659 dbSNP
rs1169274086 1672 dbSNP
rs1420846000 1673 dbSNP
rs923218319 1677 dbSNP
rs1470729754 1679 dbSNP
rs1176363831 1680 dbSNP
rs928541870 1681 dbSNP
rs1308157660 1702 dbSNP
rs938542568 1709 dbSNP
rs954618190 1719 dbSNP
rs1447723524 1720 dbSNP
rs60935796 1721 dbSNP
rs775291061 1724 dbSNP
rs542100294 1733 dbSNP
rs781582118 1736 dbSNP
rs924360230 1737 dbSNP
rs1159522318 1746 dbSNP
rs747765350 1750 dbSNP
rs934845904 1761 dbSNP
rs1221061611 1767 dbSNP
rs1279557335 1771 dbSNP
rs1057314787 1794 dbSNP
rs3830580 1800 dbSNP
rs898501443 1800 dbSNP
rs376234210 1801 dbSNP
rs1311896421 1802 dbSNP
rs72577325 1802 dbSNP
rs1222246886 1803 dbSNP
rs1357694363 1812 dbSNP
rs560363615 1821 dbSNP
rs1247278302 1825 dbSNP
rs149626067 1831 dbSNP
rs749930737 1835 dbSNP
rs552402371 1841 dbSNP
rs570893096 1845 dbSNP
rs1380207288 1850 dbSNP
rs1298373238 1854 dbSNP
rs543641667 1862 dbSNP
rs888460265 1868 dbSNP
rs1165461449 1874 dbSNP
rs1474506050 1874 dbSNP
rs1005529447 1877 dbSNP
rs75886391 1889 dbSNP
rs1016119873 1890 dbSNP
rs1192898731 1891 dbSNP
rs961470107 1897 dbSNP
rs993323383 1899 dbSNP
rs1260347520 1910 dbSNP
rs1008433088 1913 dbSNP
rs1430333955 1915 dbSNP
rs1262734702 1917 dbSNP
rs777322990 1918 dbSNP
rs1489965985 1926 dbSNP
rs964205301 1942 dbSNP
rs1223972203 1946 dbSNP
rs550176907 1955 dbSNP
rs1339267040 1958 dbSNP
rs1250316719 1970 dbSNP
rs1224635506 1976 dbSNP
rs750920654 1979 dbSNP
rs1424026251 1986 dbSNP
rs1011759361 1989 dbSNP
rs986017858 1993 dbSNP
rs1343483890 1994 dbSNP
rs1412413091 1997 dbSNP
rs1174315122 1998 dbSNP
rs1017491638 2000 dbSNP
rs1420785799 2004 dbSNP
rs565209784 2010 dbSNP
rs1166049416 2012 dbSNP
rs968807037 2023 dbSNP
rs967477935 2027 dbSNP
rs748759702 2031 dbSNP
rs978438535 2036 dbSNP
rs924390918 2037 dbSNP
rs934395323 2040 dbSNP
rs992538119 2042 dbSNP
rs779053409 2045 dbSNP
rs76806153 2048 dbSNP
rs1045062866 2051 dbSNP
rs1217697075 2052 dbSNP
rs1287845587 2053 dbSNP
rs1481334668 2054 dbSNP
rs1258125414 2058 dbSNP
rs1222570634 2059 dbSNP
rs1354179889 2060 dbSNP
rs1284755791 2062 dbSNP
rs1215691919 2072 dbSNP
rs1233747091 2077 dbSNP
rs1283758186 2088 dbSNP
rs1453325193 2094 dbSNP
rs888688247 2095 dbSNP
rs144337866 2099 dbSNP
rs746058856 2099 dbSNP
rs941385642 2106 dbSNP
rs1037025347 2107 dbSNP
rs897281995 2110 dbSNP
rs761285995 2123 dbSNP
rs1336126215 2131 dbSNP
rs998225147 2145 dbSNP
rs1029667488 2146 dbSNP
rs1173332563 2153 dbSNP
rs1198880513 2161 dbSNP
rs554898646 2162 dbSNP
rs1245630047 2169 dbSNP
rs890300545 2171 dbSNP
rs1007322920 2177 dbSNP
rs1440817894 2181 dbSNP
rs1038887578 2182 dbSNP
rs1017962457 2187 dbSNP
rs1051647 2188 dbSNP
rs1047085887 2189 dbSNP
rs978875292 2190 dbSNP
rs1031337907 2195 dbSNP
rs955657681 2196 dbSNP
rs992593449 2199 dbSNP
rs1407591503 2202 dbSNP
rs916981054 2211 dbSNP
rs948891090 2212 dbSNP
rs1314234089 2219 dbSNP
rs1039932156 2247 dbSNP
rs900012798 2248 dbSNP
rs534451456 2249 dbSNP
rs1011732882 2252 dbSNP
rs1434522999 2254 dbSNP
rs1311712977 2257 dbSNP
rs138844651 2258 dbSNP
rs941617454 2259 dbSNP
rs1239154483 2262 dbSNP
rs1306882396 2263 dbSNP
rs1037648521 2264 dbSNP
rs1182212390 2266 dbSNP
rs1178321894 2272 dbSNP
rs1358296629 2274 dbSNP
rs897169164 2275 dbSNP
rs933963152 2276 dbSNP
rs533948246 2277 dbSNP
rs889849766 2291 dbSNP
rs1218548718 2292 dbSNP
rs1007840193 2293 dbSNP
rs558383591 2294 dbSNP
rs1385153162 2298 dbSNP
rs904316757 2298 dbSNP
rs1000126791 2299 dbSNP
rs991835026 2300 dbSNP
rs1031979889 2307 dbSNP
rs1320493655 2308 dbSNP
rs1401000833 2310 dbSNP
rs1362430824 2321 dbSNP
rs955711219 2322 dbSNP
rs1474039141 2341 dbSNP
rs1359533667 2343 dbSNP
rs576841675 2356 dbSNP
rs537518538 2363 dbSNP
rs969785387 2364 dbSNP
rs1240033958 2365 dbSNP
rs1195310825 2369 dbSNP
rs555772797 2370 dbSNP
rs1267897096 2376 dbSNP
rs910052417 2402 dbSNP
rs574083785 2404 dbSNP
rs982824839 2413 dbSNP
rs1214096218 2419 dbSNP
rs973022309 2422 dbSNP
rs1272159621 2462 dbSNP
rs542122908 2464 dbSNP
rs1345352100 2472 dbSNP
rs560375797 2480 dbSNP
rs59961166 2483 dbSNP
rs1350996125 2486 dbSNP
rs1283491261 2492 dbSNP
rs1354238554 2493 dbSNP
rs1040389300 2497 dbSNP
rs1172442357 2499 dbSNP
rs1477939616 2501 dbSNP
rs1428383009 2505 dbSNP
rs1219917603 2506 dbSNP
rs900064641 2513 dbSNP
rs1489318809 2527 dbSNP
rs934017016 2533 dbSNP
rs1196407244 2544 dbSNP
rs1436209673 2545 dbSNP
rs1260071941 2549 dbSNP
rs1219523370 2550 dbSNP
rs1051033046 2554 dbSNP
rs546352973 2556 dbSNP
rs1248805698 2557 dbSNP
rs369656436 2560 dbSNP
rs1221323493 2563 dbSNP
rs1368665350 2565 dbSNP
rs1279502606 2566 dbSNP
rs775949250 2568 dbSNP
rs35156783 2569 dbSNP
rs1352327544 2571 dbSNP
rs1332751706 2581 dbSNP
rs942801966 2582 dbSNP
rs1173734846 2584 dbSNP
rs142055724 2588 dbSNP
rs182896428 2598 dbSNP
rs904370120 2599 dbSNP
rs1176617854 2600 dbSNP
rs1172836920 2602 dbSNP
rs1424461498 2603 dbSNP
rs1000415187 2604 dbSNP
rs8594 2606 dbSNP
rs891706411 2607 dbSNP
rs1212438289 2608 dbSNP
rs1166347827 2611 dbSNP
rs1283998331 2614 dbSNP
rs1222600511 2615 dbSNP
rs1379730005 2618 dbSNP
rs1404669145 2624 dbSNP
rs1013966184 2630 dbSNP
rs1333328623 2632 dbSNP
rs1023972481 2634 dbSNP
rs571815518 2644 dbSNP
rs970086911 2645 dbSNP
rs186457077 2651 dbSNP
rs1051708 2653 dbSNP
rs1316783250 2655 dbSNP
rs1023341722 2657 dbSNP
rs962928236 2660 dbSNP
rs963315983 2662 dbSNP
rs758145989 2663 dbSNP
rs1241343512 2665 dbSNP
rs1183881213 2671 dbSNP
rs542545972 2700 dbSNP
rs370999700 2702 dbSNP
rs1201377111 2716 dbSNP
rs1260553693 2720 dbSNP
rs1356218908 2721 dbSNP
rs566738409 2721 dbSNP
rs955619573 2727 dbSNP
rs1026153026 2731 dbSNP
rs1484953320 2732 dbSNP
rs986974644 2739 dbSNP
rs1264589966 2742 dbSNP
rs1397468934 2746 dbSNP
rs1379475721 2750 dbSNP
rs1287882512 2752 dbSNP
rs911230870 2759 dbSNP
rs1362156696 2760 dbSNP
rs1159241001 2762 dbSNP
rs190839060 2763 dbSNP
rs1043837207 2772 dbSNP
rs925342880 2773 dbSNP
rs935881069 2775 dbSNP
rs1466755328 2779 dbSNP
rs1171708407 2781 dbSNP
rs1261306233 2787 dbSNP
rs183027446 2788 dbSNP
rs1184945804 2789 dbSNP
rs1052935213 2791 dbSNP
rs1264348824 2792 dbSNP
rs769971291 2797 dbSNP
rs975437645 2798 dbSNP
rs1489996802 2799 dbSNP
rs921546974 2805 dbSNP
rs1421391448 2807 dbSNP
rs777582512 2813 dbSNP
rs1246389827 2814 dbSNP
rs1298712834 2819 dbSNP
rs748905648 2828 dbSNP
rs1294424145 2831 dbSNP
rs1342215297 2833 dbSNP
rs773287261 2840 dbSNP
rs1380024296 2843 dbSNP
rs1404304643 2850 dbSNP
rs1045641759 2852 dbSNP
rs570536225 2860 dbSNP
rs903382515 2862 dbSNP
rs1295174784 2864 dbSNP
rs1056831025 2868 dbSNP
rs934804120 2868 dbSNP
rs146293554 2869 dbSNP
rs1001582759 2875 dbSNP
rs1424851394 2880 dbSNP
rs1016705890 2886 dbSNP
rs1274578138 2893 dbSNP
rs1199177058 2905 dbSNP
rs898225550 2908 dbSNP
rs1044073726 2923 dbSNP
rs187571607 2925 dbSNP
rs1488554114 2926 dbSNP
rs192984644 2927 dbSNP
rs1196416036 2928 dbSNP
rs994783147 2944 dbSNP
rs1219300760 2950 dbSNP
rs1287362292 2955 dbSNP
rs1025771896 2956 dbSNP
rs1203403297 2961 dbSNP
rs955506061 2970 dbSNP
rs1303396215 2975 dbSNP
rs987027226 2989 dbSNP
rs182906150 2993 dbSNP
rs1329375472 2995 dbSNP
rs1018459091 2999 dbSNP
rs964102564 3009 dbSNP
rs878974073 3015 dbSNP
rs1401344908 3019 dbSNP
rs188163528 3021 dbSNP
rs1477250804 3023 dbSNP
rs925428202 3026 dbSNP
rs1200275833 3029 dbSNP
rs1418969519 3030 dbSNP
rs935413347 3031 dbSNP
rs1198454735 3033 dbSNP
rs1176263882 3034 dbSNP
rs988182878 3039 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23516.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgGAGUCUCCGUCGACGAa 5'
            ||||     ||||||| 
Target 5' uuCUCA-----AGCUGCUu 3'
 		9 - 22
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000381237.1 | 3UTR | UUUUAUUUUUCUCAAGCUGCUUUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000381237.1 | 3UTR | UUUUAUUUUUCUCAAGCUGCUUUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer -0.615 6.9e-4 -0.569 1.9e-3 24 Click to see details
GSE28260 Renal cortex and medulla -0.549 2.6e-2 -0.418 7.8e-2 13 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.383 2.9e-2 0.253 1.1e-1 25 Click to see details
GSE42095 Differentiated embryonic stem cells 0.305 7.9e-2 0.499 7.7e-3 23 Click to see details
GSE26953 Aortic valvular endothelial cells -0.24 1.3e-1 -0.190 1.9e-1 24 Click to see details
GSE21849 B cell lymphoma 0.215 1.3e-1 0.523 1.8e-3 29 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.209 1.9e-1 -0.033 4.5e-1 20 Click to see details
GSE21687 Ependynoma primary tumors -0.1 2.2e-1 -0.089 2.4e-1 64 Click to see details
GSE38226 Liver fibrosis -0.163 2.4e-1 -0.194 2.0e-1 21 Click to see details
GSE32688 Pancreatic cancer -0.113 2.7e-1 -0.270 6.8e-2 32 Click to see details
GSE27834 Pluripotent stem cells -0.137 3.1e-1 -0.197 2.3e-1 16 Click to see details
GSE14794 Lymphoblastoid cells 0.049 3.2e-1 0.073 2.5e-1 90 Click to see details
GSE17306 Multiple myeloma -0.021 4.4e-1 0.450 5.9e-4 49 Click to see details
GSE17498 Multiple myeloma 0.009 4.8e-1 0.134 2.0e-1 40 Click to see details
GSE17498 Multiple myeloma 0.009 4.8e-1 0.134 2.0e-1 40 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
243 hsa-miR-646 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061535 BTG2 BTG anti-proliferation factor 2 2 4
MIRT064692 CCND2 cyclin D2 2 4
MIRT068834 FNDC3A fibronectin type III domain containing 3A 2 10
MIRT079080 BIRC5 baculoviral IAP repeat containing 5 2 6
MIRT092735 SETD5 SET domain containing 5 2 4
MIRT093692 PI4K2B phosphatidylinositol 4-kinase type 2 beta 2 6
MIRT096244 CANX calnexin 2 2
MIRT096296 SQSTM1 sequestosome 1 2 4
MIRT098839 PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 2 2
MIRT100229 PRR3 proline rich 3 2 4
MIRT156479 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT186378 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT196460 TAOK1 TAO kinase 1 2 2
MIRT211252 FGF2 fibroblast growth factor 2 2 2
MIRT215233 NPM1 nucleophosmin 1 2 4
MIRT215383 CREBRF CREB3 regulatory factor 2 2
MIRT224972 BAG4 BCL2 associated athanogene 4 2 4
MIRT235598 KIF3B kinesin family member 3B 2 2
MIRT249860 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT258407 FOXK1 forkhead box K1 2 2
MIRT269359 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT310455 REST RE1 silencing transcription factor 2 2
MIRT314057 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 2 8
MIRT322288 SLC39A14 solute carrier family 39 member 14 2 2
MIRT326311 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT329703 SCD stearoyl-CoA desaturase 2 2
MIRT341278 PABPN1 poly(A) binding protein nuclear 1 2 3
MIRT403798 AKIRIN1 akirin 1 2 2
MIRT438549 NOB1 NIN1/PSMD8 binding protein 1 homolog 1 1
MIRT441908 SEPN1 selenoprotein N 2 2
MIRT444125 ZNRF3 zinc and ring finger 3 2 2
MIRT445458 EXT1 exostosin glycosyltransferase 1 2 4
MIRT446500 ASCC1 activating signal cointegrator 1 complex subunit 1 2 2
MIRT446538 GOLGA8B golgin A8 family member B 2 2
MIRT447770 DMRT2 doublesex and mab-3 related transcription factor 2 2 2
MIRT448438 TLL1 tolloid like 1 2 2
MIRT448768 GOLGA8A golgin A8 family member A 2 2
MIRT460749 SRP14 signal recognition particle 14 2 2
MIRT461556 ACTR3B ARP3 actin related protein 3 homolog B 2 2
MIRT463163 ZNF367 zinc finger protein 367 2 10
MIRT464234 VEGFA vascular endothelial growth factor A 5 12
MIRT464496 UCK2 uridine-cytidine kinase 2 2 2
MIRT465157 TSC22D2 TSC22 domain family member 2 2 2
MIRT466429 TFAP2A transcription factor AP-2 alpha 2 8
MIRT467395 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT468672 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT469407 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT470750 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT471947 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT472468 NAPG NSF attachment protein gamma 2 12
MIRT474571 KLHDC3 kelch domain containing 3 2 2
MIRT477443 ELOVL5 ELOVL fatty acid elongase 5 2 2
MIRT480541 BZW1 basic leucine zipper and W2 domains 1 2 12
MIRT482110 AKT3 AKT serine/threonine kinase 3 2 4
MIRT485206 PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha 2 8
MIRT492318 SETD1B SET domain containing 1B 2 4
MIRT497144 TAPBP TAP binding protein 2 2
MIRT498976 ORC4 origin recognition complex subunit 4 2 8
MIRT499112 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 8
MIRT499448 ODF2L outer dense fiber of sperm tails 2 like 2 8
MIRT500089 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 8
MIRT500317 ZNF622 zinc finger protein 622 2 8
MIRT500414 ZMAT3 zinc finger matrin-type 3 2 8
MIRT500572 USP53 ubiquitin specific peptidase 53 2 2
MIRT500596 UBN2 ubinuclein 2 2 10
MIRT500797 TLK1 tousled like kinase 1 2 8
MIRT500932 SRPR SRP receptor alpha subunit 2 6
MIRT500946 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 2 8
MIRT501081 SMAD7 SMAD family member 7 2 8
MIRT501515 PPTC7 PTC7 protein phosphatase homolog 2 6
MIRT501879 MOB4 MOB family member 4, phocein 2 8
MIRT502195 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT502630 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT502650 DCTN5 dynactin subunit 5 2 8
MIRT502914 CDCA4 cell division cycle associated 4 2 8
MIRT502938 CDC37L1 cell division cycle 37 like 1 2 8
MIRT502987 CCND1 cyclin D1 6 3
MIRT503181 AGO2 argonaute 2, RISC catalytic component 2 6
MIRT504532 ZNF620 zinc finger protein 620 2 6
MIRT504715 DLC1 DLC1 Rho GTPase activating protein 2 6
MIRT504967 ZNRF2 zinc and ring finger 2 2 2
MIRT505073 ZFHX4 zinc finger homeobox 4 2 6
MIRT505109 YTHDC1 YTH domain containing 1 2 6
MIRT505342 TMEM245 transmembrane protein 245 2 6
MIRT505389 TMEM100 transmembrane protein 100 2 2
MIRT505681 SESTD1 SEC14 and spectrin domain containing 1 2 6
MIRT506162 PLAG1 PLAG1 zinc finger 2 8
MIRT506185 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 6
MIRT506354 NUP50 nucleoporin 50 2 6
MIRT506480 MYO5A myosin VA 2 6
MIRT506833 KIF23 kinesin family member 23 2 6
MIRT507310 FEM1B fem-1 homolog B 2 4
MIRT507847 CCNE2 cyclin E2 2 6
MIRT508670 DIABLO diablo IAP-binding mitochondrial protein 2 4
MIRT509137 ZNF691 zinc finger protein 691 2 4
MIRT509686 ATAD5 ATPase family, AAA domain containing 5 2 4
MIRT512205 C1orf21 chromosome 1 open reading frame 21 2 6
MIRT518087 TRIM35 tripartite motif containing 35 2 2
MIRT518990 NNT nicotinamide nucleotide transhydrogenase 2 4
MIRT520964 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT521049 SLC2A3 solute carrier family 2 member 3 2 4
MIRT521192 SBNO1 strawberry notch homolog 1 2 6
MIRT521619 PSAT1 phosphoserine aminotransferase 1 2 6
MIRT522770 LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 2 2
MIRT533754 TMEM184B transmembrane protein 184B 2 2
MIRT534131 SNTB2 syntrophin beta 2 2 4
MIRT537159 GID8 GID complex subunit 8 homolog 2 2
MIRT537812 EFNB2 ephrin B2 2 4
MIRT538108 DDX6 DEAD-box helicase 6 2 2
MIRT540839 GNAT1 G protein subunit alpha transducin 1 2 4
MIRT541019 WIPI2 WD repeat domain, phosphoinositide interacting 2 2 2
MIRT541145 PISD phosphatidylserine decarboxylase 2 2
MIRT541387 CDC42SE2 CDC42 small effector 2 2 2
MIRT541422 CBX4 chromobox 4 2 2
MIRT543521 PRSS21 protease, serine 21 2 2
MIRT543794 RALGAPB Ral GTPase activating protein non-catalytic beta subunit 2 4
MIRT543831 GSG1 germ cell associated 1 2 2
MIRT544961 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT545182 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 4
MIRT545343 CCDC83 coiled-coil domain containing 83 2 2
MIRT545367 LIN7C lin-7 homolog C, crumbs cell polarity complex component 2 2
MIRT545656 SPARC secreted protein acidic and cysteine rich 2 2
MIRT545678 DECR1 2,4-dienoyl-CoA reductase 1 2 2
MIRT545938 ZBTB44 zinc finger and BTB domain containing 44 2 4
MIRT546107 USP48 ubiquitin specific peptidase 48 2 4
MIRT546603 SALL1 spalt like transcription factor 1 2 4
MIRT546628 RTN4 reticulon 4 2 2
MIRT547321 NPTN neuroplastin 2 2
MIRT547660 KPNA3 karyopherin subunit alpha 3 2 2
MIRT547994 HCFC2 host cell factor C2 2 4
MIRT548048 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548098 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 4
MIRT548721 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT548938 CDK17 cyclin dependent kinase 17 2 2
MIRT549071 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT549272 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT549438 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT550462 OSCAR osteoclast associated, immunoglobulin-like receptor 2 4
MIRT550794 WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 2 2
MIRT550819 FAM229B family with sequence similarity 229 member B 2 2
MIRT551537 EMB embigin 2 2
MIRT552031 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552340 ZNF704 zinc finger protein 704 2 2
MIRT552444 ZNF449 zinc finger protein 449 2 2
MIRT553116 UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 2
MIRT553448 TOX4 TOX high mobility group box family member 4 2 2
MIRT553725 TBX18 T-box 18 2 2
MIRT553805 SZRD1 SUZ RNA binding domain containing 1 2 4
MIRT554696 RNF149 ring finger protein 149 2 2
MIRT554831 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT555139 PTPRD protein tyrosine phosphatase, receptor type D 2 2
MIRT555269 PRDM4 PR/SET domain 4 2 2
MIRT555312 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 4
MIRT555558 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT556379 LURAP1L leucine rich adaptor protein 1 like 2 2
MIRT556669 KMT2D lysine methyltransferase 2D 2 4
MIRT556853 KANK1 KN motif and ankyrin repeat domains 1 2 4
MIRT557476 GPR27 G protein-coupled receptor 27 2 4
MIRT558361 DMTF1 cyclin D binding myb like transcription factor 1 2 2
MIRT558385 DHX33 DEAH-box helicase 33 2 2
MIRT558502 CYP26B1 cytochrome P450 family 26 subfamily B member 1 2 4
MIRT558515 CTDSPL CTD small phosphatase like 2 4
MIRT558583 CREBL2 cAMP responsive element binding protein like 2 2 4
MIRT558641 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT558653 CNKSR3 CNKSR family member 3 2 2
MIRT558865 CD2AP CD2 associated protein 2 2
MIRT558888 CCNE1 cyclin E1 2 4
MIRT559002 CA8 carbonic anhydrase 8 2 2
MIRT559149 BTN3A3 butyrophilin subfamily 3 member A3 2 2
MIRT559999 RAB3IP RAB3A interacting protein 2 2
MIRT562023 LANCL1 LanC like 1 2 2
MIRT562474 CNOT6L CCR4-NOT transcription complex subunit 6 like 2 2
MIRT562586 CBX2 chromobox 2 2 2
MIRT562595 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT562873 KIAA1456 KIAA1456 2 2
MIRT562989 KIAA0408 KIAA0408 2 4
MIRT563082 SLC25A12 solute carrier family 25 member 12 2 2
MIRT563499 DLGAP3 DLG associated protein 3 2 2
MIRT563892 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT564328 CCNT1 cyclin T1 2 2
MIRT564945 XKR7 XK related 7 2 2
MIRT564981 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT566302 PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A 2 2
MIRT566701 MTMR3 myotubularin related protein 3 2 2
MIRT566827 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 2
MIRT571236 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT571424 RIF1 replication timing regulatory factor 1 2 2
MIRT571637 SKI SKI proto-oncogene 2 2
MIRT571836 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT571962 KIF5B kinesin family member 5B 2 2
MIRT572104 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT572183 CDK6 cyclin dependent kinase 6 2 2
MIRT572720 RBL1 RB transcriptional corepressor like 1 2 2
MIRT574589 N4BP1 NEDD4 binding protein 1 2 2
MIRT575878 Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2 3
MIRT609979 HERPUD2 HERPUD family member 2 2 2
MIRT612932 GPRIN3 GPRIN family member 3 2 2
MIRT614327 C1orf220 chromosome 1 open reading frame 220 2 2
MIRT614694 TRAK1 trafficking kinesin protein 1 2 2
MIRT618328 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT618456 ZFP30 ZFP30 zinc finger protein 2 4
MIRT621135 EMC7 ER membrane protein complex subunit 7 2 4
MIRT622878 PDE12 phosphodiesterase 12 2 4
MIRT631163 CCBE1 collagen and calcium binding EGF domains 1 2 2
MIRT632793 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT636731 AFAP1 actin filament associated protein 1 2 2
MIRT649297 IRF8 interferon regulatory factor 8 2 2
MIRT650955 QPCTL glutaminyl-peptide cyclotransferase like 2 2
MIRT653267 SOGA3 SOGA family member 3 2 2
MIRT654665 PSMG1 proteasome assembly chaperone 1 2 2
MIRT656180 MPRIP myosin phosphatase Rho interacting protein 2 2
MIRT659252 CUL3 cullin 3 2 2
MIRT663826 NLRP12 NLR family pyrin domain containing 12 2 4
MIRT676632 CSNK1E casein kinase 1 epsilon 2 2
MIRT679503 ZNF106 zinc finger protein 106 2 2
MIRT680978 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT682272 RS1 retinoschisin 1 2 2
MIRT682421 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT682510 GLP2R glucagon like peptide 2 receptor 2 2
MIRT693926 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT700660 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT700740 PLEKHA8 pleckstrin homology domain containing A8 2 2
MIRT702871 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT703192 GPBP1 GC-rich promoter binding protein 1 2 2
MIRT704453 CSNK2A1 casein kinase 2 alpha 1 2 2
MIRT704709 CHEK1 checkpoint kinase 1 2 2
MIRT706164 CASK calcium/calmodulin dependent serine protein kinase 2 3
MIRT713334 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 2
MIRT713416 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT716300 PAX1 paired box 1 2 2
MIRT717394 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT718453 BTNL9 butyrophilin like 9 2 2
MIRT718728 VWA9 integrator complex subunit 14 2 2
MIRT719029 SHROOM3 shroom family member 3 2 2
MIRT720367 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT723120 ZSCAN16 zinc finger and SCAN domain containing 16 2 2
MIRT733741 EGFR epidermal growth factor receptor 4 0
MIRT734281 HIF1A hypoxia inducible factor 1 alpha subunit 3 0
MIRT735934 EYA3 EYA transcriptional coactivator and phosphatase 3 3 0
MIRT755830 IGF1 insulin like growth factor 1 5 1
MIRT755831 BCL2 BCL2, apoptosis regulator 4 1
MIRT755832 CDK2 cyclin dependent kinase 2 4 1
MIRT755833 BAX BCL2 associated X, apoptosis regulator 4 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-646 Fluorouracil 3385 NSC19893 approved resistant cell line (OE19)
hsa-miR-646 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM16)
hsa-miR-646 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM43)
hsa-miR-646 Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-646 Oxaliplatin 6857599 NSC266046 approved sensitive cell line (IGROV-1)
hsa-miR-646 Cisplatin 5460033 NSC119875 approved sensitive cell line (IGROV-1)
hsa-miR-646 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-646 Cisplatin 5460033 NSC119875 approved sensitive cell line (H460)

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