miRTarBase - #MIRT322410


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pre-miRNA Information
pre-miRNA hsa-mir-605   
Genomic Coordinates chr10: 51299573 - 51299655
Synonyms MIRN605, hsa-mir-605, MIR605
Description Homo sapiens miR-605 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-605-3p
Sequence 51| AGAAGGCACUAUGAGAUUUAGA |72
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 10 + 51299626 27587585, 28550310, 26028588, 26449202, 26487287, 29165639 MiREDiBase
A-to-I 14 10 + 51299636 29233923 MiREDiBase
A-to-I 20 10 + 51299642 18684997, 26449202, 27587585, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs759219082 5 dbSNP
rs1491224174 9 dbSNP
rs746611214 10 dbSNP
rs367648737 11 dbSNP
rs1359467239 14 dbSNP
rs1442565019 16 dbSNP
Putative Targets

Gene Information
Gene Symbol PPP2R2A   
Synonyms B55A, B55ALPHA, PR52A, PR55A, PR55alpha
Description protein phosphatase 2 regulatory subunit Balpha
Transcript NM_001177591   
Other Transcripts NM_002717   
Expression
Putative miRNA Targets on PPP2R2A
3'UTR of PPP2R2A
(miRNA target sites are highlighted)		 
>PPP2R2A|NM_001177591|3'UTR
   1 GGTTGGCATTCCTAGCAGAAGAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAG
  81 AGGTCCATTGTGGCGCCCCTTTCCAGTGTTTGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCT
 161 CTGTGGATTCATCACTGTGGTGTTCTCCATGTCTGCTAGCCATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTT
 241 CTTGCACCATCTTGCCTAATGGACTAGATTGGACTGTATCAACATTGATTTACTCCACTTTTTATGCCTTCCATTGTGAT
 321 GACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATTTAATTGTGTATCCTCATTACTGTATCATTTGTGGGGTA
 401 CACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCTTGTAGCATTCCTCCTCTTCTGGCCTCCTG
 481 GACTGCTCCCCTTCATCTCTTACCCTTGCCCCCTCCACCCGGTCTTGGTGGTGGTATATTAAAAAAAGAAAGAATGAAAG
 561 CACACAAAATGAGTCAGTTTGGGGTCAGTGGTATAAAGGGGGTATATGTTGCAAACAAATGTTTTAGTAACAGTTGGCTG
 641 TAATCACTCCTCGCCGTGTCTGGCACTGAAAATAAGGAAAAAAAACCTACTACTGAATAAAAGTGACAAAGAATGGAGAA
 721 TCTGGTTTTCTTTTTCTTTTTAACCTACCTCTTGTAGCCAATATTTTGTGTCATACCTTTGGGCACAGTGAAACAAAATG
 801 GGTTTTCATTGTTTATTGGTATTTTTGTTAATTATTTTTAACAAGTGTTCTTTTACATGCAGGAGGAGAGGTATTGGTTC
 881 TCTATGAACATATTTTGAATATAGGTTTTATTAAGGATTTCACAATCTATAAATGCTACTAGTTTTTTTTTTTTTTTTTA
 961 CCATCATGAGGGTATTGGATACATTGTGTCTCTATTTAACTCATTATGTGTTAATGAAATTGTTGTAAATGGGAACCAAA
1041 TTTGTAGAACTTAATTTCTACTTTTTAGAGTGCTTAATTTCATTTTTGCCTTACTAAATAGTCAAAGACTTATAAAACAT
1121 TTTTAACAAGTTAGAACTTTTTTGTTATTCAGTCATATAAAATAGCAGAAAACTAACATCAAGTGACACTGCACTAAATA
1201 CTTTTTTTGTATTTTACTGCTATCAAATCAGAATGAAATATACTTTACCATAGATATTTTTCTTCTATTTTTGGTTTTCC
1281 AAAGCTATATGAAAGACAAATTTTTAAAGGTACAGCGTTCAAAAAGTGCTTAATGAACTCCAACAGCTGCCTCAAATAAA
1361 AATCTGTATATGAATACATTTTCCCTAAGCGGTGATACATTATCCAAAGATGAAGAGTGCTCCTATTTTTAATAGGTAGA
1441 ATGTACCTTTGTCAGTCTTGCAGAAACTTTAATGGAGAAGAAATGGACTTTATTTTTGAAAGGTGAAATGAACAGGCATT
1521 TATATTATTAGAGAATGGTAGTCTTATTTTGGTGGAACATAATGTAACAACCTTGAATTTCAGAGGACTCTGAGTGCTTC
1601 TATGTCCACTACCTATTGTTCTATTCTTCAATAATGAAAAAGAATTCAACGAGCCGACCGTGATTCCCTCTACTACAAAT
1681 ATTATGTCTTGTAAGTTAGCATTTTTAGCACACAGGAGAAATTTTATGTAATAAAATTACTGTATCTTTTGGATTTAACA
1761 AATTTGTATTTGAAACACATTCTATGTCTGATAATTCTTAATGGCACTTTTACTAATTTATTTGGGGATCTTGGGTACAT
1841 TCTTAATTTGTGTTTATTCTTCACGCTTGACTTGCAAGTGGGATATTCCCCTGCCACAAGTGTCAAACAGTGATATTCTT
1921 CCTGTGTTGTGACTGGACAGTTTTCCAGATCTTTTTTGGGAGATTTTCCTACAGCTTGGTTGTATGTCTTGAGATAACAC
2001 CACCAAACAGCTCTCAGAAATTCTTTTTTGATTGATCAGTAGCTATGATGATTCTCCTCCATGACACTAAGGATTAGTTT
2081 ATATATTTAAGAGAAATAATTGCTAAAATTAAAATGCCTCTATCAAGGAATGCTATTATAAATTATTGTTAACATTCTCA
2161 AGTATTAATTTTTTAATTTCATTGGTGTAGCAAACTCTAAGCCCAGCCACTCATTTTACATGGCCATGGTTAATCTTTTT
2241 ATTAATAAAAATTATACTTAGAATAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agauuUAGAGUAUCACGGAAGa 5'
               | :|: || ||||||| 
Target 5' actccACTTTTTA-TGCCTTCc 3'
 292 - 312 148.00 -10.30
2 
miRNA  3' agAUUUAGAGU-AUCACGGAAga 5'
            | |||:||| |  ||||||  
Target 5' gcTTAATTTCATTTTTGCCTTac 3'
 1072 - 1094 144.00 -15.50
3 
miRNA  3' agaUUUAGAGUAUCACGGAAga 5'
             |||| |:|   ||:|||  
Target 5' tacAAATATTA---TGTCTTgt 3'
 1674 - 1692 120.00 -5.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM9828919 3 COSMIC
COSN30475301 26 COSMIC
COSN30515398 41 COSMIC
COSN31584626 59 COSMIC
COSN31526004 77 COSMIC
COSN31956942 79 COSMIC
COSN30101997 86 COSMIC
COSN30497665 96 COSMIC
COSN30152864 105 COSMIC
COSN14337613 128 COSMIC
COSN28202085 265 COSMIC
COSN2458648 428 COSMIC
COSN24105017 601 COSMIC
COSN17625151 679 COSMIC
COSN31534880 707 COSMIC
COSN1363159 746 COSMIC
COSN27274496 960 COSMIC
COSN27518201 960 COSMIC
COSN32064459 1292 COSMIC
COSN6920106 1375 COSMIC
COSN17708943 1780 COSMIC
COSN26423455 1970 COSMIC
COSN9260146 2109 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs774895335 3 dbSNP
rs759874193 6 dbSNP
rs748011679 8 dbSNP
rs1436181098 9 dbSNP
rs767917014 11 dbSNP
rs180964025 17 dbSNP
rs761470863 22 dbSNP
rs764825800 28 dbSNP
rs1283526764 29 dbSNP
rs554125616 29 dbSNP
rs749971120 31 dbSNP
rs904446362 37 dbSNP
rs757896097 41 dbSNP
rs1191586404 43 dbSNP
rs1352957350 47 dbSNP
rs1172694055 55 dbSNP
rs958812500 57 dbSNP
rs545358878 61 dbSNP
rs1012729614 65 dbSNP
rs1190009113 69 dbSNP
rs1032591036 71 dbSNP
rs536939041 72 dbSNP
rs1476401449 75 dbSNP
rs764920656 75 dbSNP
rs1281719718 78 dbSNP
rs1024153011 83 dbSNP
rs558799005 94 dbSNP
rs1157852427 95 dbSNP
rs377473455 96 dbSNP
rs1458529388 109 dbSNP
rs1022564404 119 dbSNP
rs907914936 123 dbSNP
rs981181822 127 dbSNP
rs185944282 128 dbSNP
rs1349113696 129 dbSNP
rs1357169880 133 dbSNP
rs545688013 136 dbSNP
rs772984241 143 dbSNP
rs1371533048 144 dbSNP
rs370119897 150 dbSNP
rs1462572160 153 dbSNP
rs923523259 154 dbSNP
rs1349321663 156 dbSNP
rs1163435312 159 dbSNP
rs1463509133 160 dbSNP
rs1276551621 162 dbSNP
rs1181986941 166 dbSNP
rs932153177 172 dbSNP
rs1050581506 173 dbSNP
rs190470052 184 dbSNP
rs1227703209 187 dbSNP
rs765240712 190 dbSNP
rs574835759 197 dbSNP
rs943242694 198 dbSNP
rs1271945448 202 dbSNP
rs1039066393 212 dbSNP
rs947194230 214 dbSNP
rs1041482200 222 dbSNP
rs902882606 235 dbSNP
rs1273735335 239 dbSNP
rs1238067447 240 dbSNP
rs1314847935 242 dbSNP
rs1309446276 247 dbSNP
rs1392138822 260 dbSNP
rs1002523670 262 dbSNP
rs1057090988 267 dbSNP
rs1367131118 271 dbSNP
rs1324028540 273 dbSNP
rs540547281 284 dbSNP
rs894364791 286 dbSNP
rs933403500 290 dbSNP
rs1804224 291 dbSNP
rs1395944729 296 dbSNP
rs1158993439 308 dbSNP
rs1452100404 312 dbSNP
rs1365860570 313 dbSNP
rs866322647 324 dbSNP
rs1419345696 325 dbSNP
rs1251972367 333 dbSNP
rs1285163501 337 dbSNP
rs1451393823 339 dbSNP
rs1219744284 343 dbSNP
rs1042516496 345 dbSNP
rs1253560903 349 dbSNP
rs1204425104 355 dbSNP
rs1026780708 356 dbSNP
rs1262308946 358 dbSNP
rs902588588 360 dbSNP
rs1347506883 371 dbSNP
rs1301524097 391 dbSNP
rs1236598959 397 dbSNP
rs1001070796 399 dbSNP
rs866980272 406 dbSNP
rs1320501345 409 dbSNP
rs1380984817 409 dbSNP
rs1387741076 409 dbSNP
rs1228316420 414 dbSNP
rs1465850684 414 dbSNP
rs867628005 414 dbSNP
rs1394103847 415 dbSNP
rs1490676354 421 dbSNP
rs1006289518 428 dbSNP
rs1034369838 430 dbSNP
rs559331518 431 dbSNP
rs1012427436 433 dbSNP
rs1473259346 450 dbSNP
rs1014943730 451 dbSNP
rs200163084 454 dbSNP
rs375142927 460 dbSNP
rs556747988 460 dbSNP
rs1278476787 466 dbSNP
rs1403409985 476 dbSNP
rs1418025541 477 dbSNP
rs976026101 498 dbSNP
rs1213228500 499 dbSNP
rs576153090 510 dbSNP
rs1269716813 512 dbSNP
rs1225308656 514 dbSNP
rs1365928244 516 dbSNP
rs543530507 518 dbSNP
rs1002942540 519 dbSNP
rs1348738599 520 dbSNP
rs1026090396 521 dbSNP
rs950500418 522 dbSNP
rs752656516 523 dbSNP
rs909016770 529 dbSNP
rs953613168 535 dbSNP
rs1474140426 540 dbSNP
rs1355981994 542 dbSNP
rs964630685 545 dbSNP
rs1193744379 547 dbSNP
rs3208440 549 dbSNP
rs986784338 570 dbSNP
rs1255088455 573 dbSNP
rs182208064 594 dbSNP
rs923178193 598 dbSNP
rs186792201 600 dbSNP
rs1341487736 603 dbSNP
rs1252429816 607 dbSNP
rs1041513585 608 dbSNP
rs924335195 609 dbSNP
rs1354074168 618 dbSNP
rs1295549214 619 dbSNP
rs1415764585 620 dbSNP
rs1340772317 641 dbSNP
rs376149347 653 dbSNP
rs938341443 654 dbSNP
rs1056766940 656 dbSNP
rs894386373 657 dbSNP
rs924073949 667 dbSNP
rs1460893076 671 dbSNP
rs1053896248 678 dbSNP
rs936736724 678 dbSNP
rs895286755 679 dbSNP
rs1012875239 684 dbSNP
rs1048776183 686 dbSNP
rs1179860682 686 dbSNP
rs1213117290 687 dbSNP
rs1333406750 688 dbSNP
rs1275591528 693 dbSNP
rs763972265 695 dbSNP
rs190800006 707 dbSNP
rs1439524977 708 dbSNP
rs528872552 712 dbSNP
rs1337130903 715 dbSNP
rs1385658204 719 dbSNP
rs530614334 727 dbSNP
rs1428820955 728 dbSNP
rs1002564898 750 dbSNP
rs1392287298 753 dbSNP
rs888309610 762 dbSNP
rs183030341 771 dbSNP
rs1405760846 787 dbSNP
rs1406925061 789 dbSNP
rs1372264517 792 dbSNP
rs1391880442 801 dbSNP
rs1364583045 803 dbSNP
rs1193158738 806 dbSNP
rs1467143621 810 dbSNP
rs546958152 812 dbSNP
rs766919381 814 dbSNP
rs950509300 816 dbSNP
rs754429513 817 dbSNP
rs1214815706 828 dbSNP
rs559624406 828 dbSNP
rs964578845 843 dbSNP
rs1225810158 846 dbSNP
rs1352471188 848 dbSNP
rs1309528982 850 dbSNP
rs567447236 856 dbSNP
rs897877749 858 dbSNP
rs1327880918 861 dbSNP
rs1446157969 864 dbSNP
rs1437157837 872 dbSNP
rs1286130399 877 dbSNP
rs1344507209 883 dbSNP
rs1316027995 885 dbSNP
rs974566793 890 dbSNP
rs997472235 891 dbSNP
rs1173188343 893 dbSNP
rs1452686887 898 dbSNP
rs1030369795 901 dbSNP
rs1191816576 902 dbSNP
rs1475402737 903 dbSNP
rs1240851613 904 dbSNP
rs1218466610 906 dbSNP
rs1228042071 914 dbSNP
rs1447877292 925 dbSNP
rs978137110 926 dbSNP
rs1345012841 928 dbSNP
rs923910580 930 dbSNP
rs1305053837 939 dbSNP
rs1196853994 942 dbSNP
rs1404374346 942 dbSNP
rs1162310551 943 dbSNP
rs1176953844 943 dbSNP
rs1377480095 943 dbSNP
rs1409449716 943 dbSNP
rs1417999732 943 dbSNP
rs202240879 943 dbSNP
rs758191963 943 dbSNP
rs953494269 944 dbSNP
rs1053761515 946 dbSNP
rs1186227547 947 dbSNP
rs1257306040 947 dbSNP
rs1282010556 949 dbSNP
rs986430181 949 dbSNP
rs1022277577 950 dbSNP
rs1306352176 953 dbSNP
rs34324006 960 dbSNP
rs968895676 960 dbSNP
rs1348461451 961 dbSNP
rs1433354811 962 dbSNP
rs1243295428 964 dbSNP
rs1341023992 965 dbSNP
rs1448655199 966 dbSNP
rs948250405 967 dbSNP
rs114986179 970 dbSNP
rs906801337 971 dbSNP
rs1391778434 980 dbSNP
rs1172581897 984 dbSNP
rs1466648163 989 dbSNP
rs1417757599 991 dbSNP
rs147587598 993 dbSNP
rs371490848 993 dbSNP
rs1171907687 995 dbSNP
rs368554109 998 dbSNP
rs1401616487 1004 dbSNP
rs1412798240 1009 dbSNP
rs930190258 1013 dbSNP
rs1338951400 1016 dbSNP
rs1383729070 1020 dbSNP
rs536584115 1023 dbSNP
rs1047398336 1030 dbSNP
rs886073052 1040 dbSNP
rs546593777 1050 dbSNP
rs1336606060 1055 dbSNP
rs1328539650 1061 dbSNP
rs566731560 1069 dbSNP
rs1313739772 1093 dbSNP
rs144866301 1095 dbSNP
rs538658833 1095 dbSNP
rs1300029194 1097 dbSNP
rs558869999 1102 dbSNP
rs938372501 1103 dbSNP
rs754873181 1104 dbSNP
rs1324397777 1106 dbSNP
rs1369374043 1110 dbSNP
rs1463364205 1110 dbSNP
rs1158798298 1114 dbSNP
rs1418199452 1115 dbSNP
rs1405328895 1116 dbSNP
rs992986471 1119 dbSNP
rs749982821 1123 dbSNP
rs1180047795 1128 dbSNP
rs762224646 1131 dbSNP
rs1016060673 1138 dbSNP
rs1211691593 1138 dbSNP
rs1265859190 1138 dbSNP
rs1238041398 1140 dbSNP
rs1342267074 1142 dbSNP
rs948371463 1145 dbSNP
rs1201611757 1155 dbSNP
rs1263200250 1164 dbSNP
rs1464209542 1169 dbSNP
rs76963037 1184 dbSNP
rs1370271894 1188 dbSNP
rs1048323956 1194 dbSNP
rs888335283 1201 dbSNP
rs900234353 1202 dbSNP
rs1249715436 1203 dbSNP
rs1428847537 1204 dbSNP
rs1198120616 1206 dbSNP
rs996039204 1208 dbSNP
rs1030549158 1210 dbSNP
rs1288714457 1212 dbSNP
rs1477089706 1212 dbSNP
rs1178749981 1215 dbSNP
rs1406919806 1216 dbSNP
rs1456957728 1217 dbSNP
rs1318727635 1218 dbSNP
rs954667614 1222 dbSNP
rs978373299 1223 dbSNP
rs1031006899 1225 dbSNP
rs1191178029 1229 dbSNP
rs575372384 1235 dbSNP
rs147481160 1236 dbSNP
rs1267962358 1240 dbSNP
rs1323488794 1244 dbSNP
rs1484737487 1247 dbSNP
rs989424951 1253 dbSNP
rs916694311 1263 dbSNP
rs1301404488 1285 dbSNP
rs1036784603 1293 dbSNP
rs1225882011 1300 dbSNP
rs901008872 1301 dbSNP
rs928084645 1303 dbSNP
rs1327845601 1307 dbSNP
rs779524369 1315 dbSNP
rs140014910 1317 dbSNP
rs574674548 1318 dbSNP
rs565920489 1321 dbSNP
rs560627499 1323 dbSNP
rs1208963641 1331 dbSNP
rs780454723 1336 dbSNP
rs1467067059 1340 dbSNP
rs1453326263 1343 dbSNP
rs1192319186 1348 dbSNP
rs1200025319 1354 dbSNP
rs570279197 1359 dbSNP
rs1007951668 1365 dbSNP
rs1194090071 1366 dbSNP
rs1021893183 1376 dbSNP
rs968925225 1379 dbSNP
rs977589021 1391 dbSNP
rs577428100 1392 dbSNP
rs1225828571 1393 dbSNP
rs1454490354 1414 dbSNP
rs1320593311 1423 dbSNP
rs1279295402 1426 dbSNP
rs1414542073 1434 dbSNP
rs537225732 1437 dbSNP
rs1331724095 1439 dbSNP
rs1397292044 1444 dbSNP
rs1037357715 1448 dbSNP
rs1166773149 1450 dbSNP
rs1460449439 1458 dbSNP
rs1388983298 1474 dbSNP
rs1407349854 1481 dbSNP
rs992614710 1484 dbSNP
rs915620655 1487 dbSNP
rs549535288 1489 dbSNP
rs1255691707 1492 dbSNP
rs900265390 1511 dbSNP
rs948426839 1514 dbSNP
rs1249961928 1515 dbSNP
rs1194134311 1516 dbSNP
rs984158056 1519 dbSNP
rs1320699051 1523 dbSNP
rs772482506 1539 dbSNP
rs1233068917 1544 dbSNP
rs1333085214 1544 dbSNP
rs1407380269 1544 dbSNP
rs1308713335 1547 dbSNP
rs1282100445 1551 dbSNP
rs115868249 1560 dbSNP
rs1327671757 1563 dbSNP
rs1030165306 1566 dbSNP
rs939977768 1569 dbSNP
rs1243612608 1591 dbSNP
rs1460752058 1591 dbSNP
rs1415346598 1601 dbSNP
rs530651612 1603 dbSNP
rs999357035 1604 dbSNP
rs1179750560 1606 dbSNP
rs1361268780 1613 dbSNP
rs1223168925 1616 dbSNP
rs140352197 1616 dbSNP
rs1239342658 1624 dbSNP
rs550681147 1630 dbSNP
rs1031362931 1632 dbSNP
rs1467501750 1640 dbSNP
rs1292528845 1646 dbSNP
rs1250894706 1651 dbSNP
rs778123294 1652 dbSNP
rs560932117 1656 dbSNP
rs529870099 1657 dbSNP
rs1378416518 1659 dbSNP
rs889173403 1660 dbSNP
rs1007568395 1661 dbSNP
rs529844103 1672 dbSNP
rs969448738 1673 dbSNP
rs1405669489 1675 dbSNP
rs1384537972 1680 dbSNP
rs1157026917 1683 dbSNP
rs1409987370 1685 dbSNP
rs904521681 1709 dbSNP
rs999143580 1720 dbSNP
rs1031915996 1731 dbSNP
rs1356966460 1733 dbSNP
rs1193061295 1741 dbSNP
rs1453177961 1747 dbSNP
rs960212941 1762 dbSNP
rs535018973 1763 dbSNP
rs1048527 1765 dbSNP
rs1213961551 1766 dbSNP
rs1355369711 1773 dbSNP
rs1286172148 1775 dbSNP
rs751470322 1785 dbSNP
rs770684877 1792 dbSNP
rs1365407960 1801 dbSNP
rs1276479172 1804 dbSNP
rs1436955774 1806 dbSNP
rs1325596753 1807 dbSNP
rs941564536 1811 dbSNP
rs1370424044 1814 dbSNP
rs1421802289 1814 dbSNP
rs1022720606 1817 dbSNP
rs1361394223 1822 dbSNP
rs1340456359 1823 dbSNP
rs1412768804 1827 dbSNP
rs1427883274 1828 dbSNP
rs538913890 1830 dbSNP
rs552198352 1832 dbSNP
rs1299454864 1836 dbSNP
rs377153264 1843 dbSNP
rs1192233998 1860 dbSNP
rs1475311912 1865 dbSNP
rs1395146941 1866 dbSNP
rs1037389186 1875 dbSNP
rs1489102248 1876 dbSNP
rs983881970 1879 dbSNP
rs1209541383 1883 dbSNP
rs1015717602 1888 dbSNP
rs921558663 1888 dbSNP
rs1384729334 1892 dbSNP
rs578063141 1898 dbSNP
rs1246360485 1905 dbSNP
rs776665560 1905 dbSNP
rs1338643364 1906 dbSNP
rs909583438 1907 dbSNP
rs1273629162 1909 dbSNP
rs1276132557 1910 dbSNP
rs931757066 1913 dbSNP
rs1312442797 1915 dbSNP
rs1445941946 1918 dbSNP
rs759708149 1921 dbSNP
rs1360929627 1922 dbSNP
rs1051982401 1932 dbSNP
rs185813923 1935 dbSNP
rs1422096817 1944 dbSNP
rs11543360 1952 dbSNP
rs1173275068 1953 dbSNP
rs890206242 1964 dbSNP
rs999797128 1970 dbSNP
rs539767602 1973 dbSNP
rs893745020 1982 dbSNP
rs1210188465 1989 dbSNP
rs1480971308 1992 dbSNP
rs1437234354 1995 dbSNP
rs1256003674 1996 dbSNP
rs568888425 1999 dbSNP
rs1318272608 2000 dbSNP
rs1292942404 2024 dbSNP
rs1241450223 2028 dbSNP
rs1226864957 2032 dbSNP
rs1381594065 2036 dbSNP
rs537981148 2038 dbSNP
rs1441563818 2039 dbSNP
rs922500873 2050 dbSNP
rs781276398 2054 dbSNP
rs1023601342 2055 dbSNP
rs557744026 2056 dbSNP
rs1421747957 2066 dbSNP
rs1003544096 2070 dbSNP
rs1181942298 2072 dbSNP
rs771683029 2074 dbSNP
rs951483644 2083 dbSNP
rs1236312063 2089 dbSNP
rs1428432764 2089 dbSNP
rs910641235 2094 dbSNP
rs190191009 2101 dbSNP
rs534140777 2111 dbSNP
rs983368417 2119 dbSNP
rs1173139422 2121 dbSNP
rs1043155807 2125 dbSNP
rs1264695223 2129 dbSNP
rs775632399 2133 dbSNP
rs910026756 2135 dbSNP
rs1313634492 2140 dbSNP
rs1354641670 2141 dbSNP
rs764047286 2146 dbSNP
rs1300723967 2154 dbSNP
rs1407914032 2160 dbSNP
rs1374703926 2161 dbSNP
rs1311512601 2164 dbSNP
rs554336022 2165 dbSNP
rs577515702 2173 dbSNP
rs774869146 2194 dbSNP
rs1394371774 2198 dbSNP
rs879594364 2200 dbSNP
rs1053376866 2203 dbSNP
rs1362738562 2218 dbSNP
rs546456983 2220 dbSNP
rs896022832 2227 dbSNP
rs1418599121 2230 dbSNP
rs1377993580 2240 dbSNP
rs1014427128 2242 dbSNP
rs558621939 2243 dbSNP
rs1216277183 2252 dbSNP
rs1440305314 2253 dbSNP
rs975627295 2254 dbSNP
rs3177715 2265 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agauuUAGAGUAUCACGGAAGa 5'
               | :|: || ||||||| 
Target 5' acuccACUUUUUA-UGCCUUCc 3'
 		15 - 35
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000380737.3 | 3UTR | AUCAACAUUGAUUUACUCCACUUUUUAUGCCUUCCAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
100 hsa-miR-605-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061339 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT061584 BTG2 BTG anti-proliferation factor 2 2 6
MIRT076140 WDR81 WD repeat domain 81 2 2
MIRT079361 CCDC137 coiled-coil domain containing 137 2 2
MIRT079547 VAMP3 vesicle associated membrane protein 3 2 2
MIRT096242 CANX calnexin 2 2
MIRT243877 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT249186 AKIRIN1 akirin 1 2 8
MIRT273604 SP1 Sp1 transcription factor 2 2
MIRT316766 FOXC1 forkhead box C1 2 4
MIRT322410 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT370117 TRIB3 tribbles pseudokinase 3 2 2
MIRT392725 UBN2 ubinuclein 2 2 2
MIRT406910 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT407440 CTDSP1 CTD small phosphatase 1 2 2
MIRT441887 RD3 retinal degeneration 3 2 4
MIRT444979 C15orf52 chromosome 15 open reading frame 52 2 2
MIRT445241 FOXD4 forkhead box D4 2 2
MIRT445500 FOXD4L5 forkhead box D4 like 5 2 2
MIRT445503 FOXD4L4 forkhead box D4 like 4 2 2
MIRT447025 FOXD4L1 forkhead box D4 like 1 2 2
MIRT447743 TMCC3 transmembrane and coiled-coil domain family 3 2 2
MIRT448761 HDX highly divergent homeobox 2 2
MIRT450003 HAX1 HCLS1 associated protein X-1 2 2
MIRT452830 FAM131B family with sequence similarity 131 member B 2 2
MIRT452872 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT453506 ARRB1 arrestin beta 1 2 2
MIRT454169 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT458742 CES2 carboxylesterase 2 2 2
MIRT459166 HSPA6 heat shock protein family A (Hsp70) member 6 2 21
MIRT460246 IL17RB interleukin 17 receptor B 2 4
MIRT460514 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT460698 RNF157 ring finger protein 157 2 2
MIRT461481 METTL1 methyltransferase like 1 2 2
MIRT462617 C20orf27 chromosome 20 open reading frame 27 2 4
MIRT463233 ZNF131 zinc finger protein 131 2 2
MIRT465699 TNPO2 transportin 2 2 8
MIRT466304 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT468957 RPS14 ribosomal protein S14 2 6
MIRT469571 RARA retinoic acid receptor alpha 2 2
MIRT469685 RAB5B RAB5B, member RAS oncogene family 2 2
MIRT470800 PMP22 peripheral myelin protein 22 2 2
MIRT471649 PANK2 pantothenate kinase 2 2 4
MIRT471722 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT472281 NFIB nuclear factor I B 2 4
MIRT473680 MAPKBP1 mitogen-activated protein kinase binding protein 1 2 2
MIRT475859 H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase 2 2
MIRT477326 EPHA2 EPH receptor A2 2 2
MIRT477831 DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 2 2
MIRT478572 CTNND1 catenin delta 1 2 4
MIRT479634 CD81 CD81 molecule 2 2
MIRT481950 ANKRD11 ankyrin repeat domain 11 2 2
MIRT483696 ZNF74 zinc finger protein 74 2 6
MIRT488798 MALT1 MALT1 paracaspase 2 2
MIRT489066 STARD3 StAR related lipid transfer domain containing 3 2 2
MIRT492533 PSMD11 proteasome 26S subunit, non-ATPase 11 2 2
MIRT492857 NRARP NOTCH regulated ankyrin repeat protein 2 2
MIRT496793 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 2 2
MIRT500122 ZNF106 zinc finger protein 106 2 4
MIRT505359 TMEM167A transmembrane protein 167A 2 2
MIRT506786 KLHL15 kelch like family member 15 2 6
MIRT510692 SRM spermidine synthase 2 6
MIRT515841 CEP104 centrosomal protein 104 2 4
MIRT516448 ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 2 4
MIRT528855 PKP1 plakophilin 1 2 2
MIRT533848 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT539025 ATXN7L1 ataxin 7 like 1 2 4
MIRT542872 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT546543 SATB2 SATB homeobox 2 2 2
MIRT554114 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT560569 ZNF460 zinc finger protein 460 2 2
MIRT560796 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT562836 GCFC2 GC-rich sequence DNA-binding factor 2 2 2
MIRT563109 IFRD2 interferon related developmental regulator 2 2 2
MIRT564177 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT564283 ASB1 ankyrin repeat and SOCS box containing 1 2 2
MIRT564350 USP22 ubiquitin specific peptidase 22 2 2
MIRT565279 TNFRSF21 TNF receptor superfamily member 21 2 2
MIRT565338 TMEM104 transmembrane protein 104 2 2
MIRT565905 SCAMP2 secretory carrier membrane protein 2 2 2
MIRT567108 ITGB1 integrin subunit beta 1 2 2
MIRT567601 FANCF Fanconi anemia complementation group F 2 2
MIRT567779 DGAT2 diacylglycerol O-acyltransferase 2 2 2
MIRT568075 CENPQ centromere protein Q 2 2
MIRT624304 COL12A1 collagen type XII alpha 1 chain 2 2
MIRT644395 CDKL1 cyclin dependent kinase like 1 2 2
MIRT661547 ZNF674 zinc finger protein 674 2 4
MIRT670949 IRAK3 interleukin 1 receptor associated kinase 3 2 2
MIRT672951 AKAP5 A-kinase anchoring protein 5 2 2
MIRT697426 ZFP36 ZFP36 ring finger protein 2 2
MIRT700793 PIAS2 protein inhibitor of activated STAT 2 2 2
MIRT702657 ITGA3 integrin subunit alpha 3 2 2
MIRT708945 FZR1 fizzy and cell division cycle 20 related 1 2 2
MIRT713657 PLCE1 phospholipase C epsilon 1 2 2
MIRT719239 CYSLTR2 cysteinyl leukotriene receptor 2 2 2
MIRT719951 BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 2 2
MIRT722048 HLA-E major histocompatibility complex, class I, E 2 2
MIRT722201 URM1 ubiquitin related modifier 1 2 2
MIRT724790 C1D C1D nuclear receptor corepressor 2 2
MIRT734347 CYP2B6 cytochrome P450 family 2 subfamily B member 6 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-605 Anthranilamide-pyrazolo[1,5-a]pyrimidine NULL NULL Quantitative real-time PCR neuroblastoma cells 23992861 2013 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-605 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-605 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-605-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)

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