miRTarBase - #MIRT326910


—
pre-miRNA Information
pre-miRNA hsa-mir-4477a   
Genomic Coordinates chr9: 41233755 - 41233835
Description Homo sapiens miR-4477a stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4477a
Sequence 48| CUAUUAAGGACAUUUGUGAUUC |69
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1281813060 1 dbSNP
rs1352899679 1 dbSNP
rs1283566158 2 dbSNP
rs1236244724 4 dbSNP
rs75019967 4 dbSNP
rs1348124293 5 dbSNP
rs34026740 8 dbSNP
rs1288237115 9 dbSNP
rs71262206 10 dbSNP
rs1355759977 11 dbSNP
rs1300249508 16 dbSNP
rs1328879592 18 dbSNP
rs139133717 20 dbSNP
Putative Targets

Gene Information
Gene Symbol SCML2   
Synonyms -
Description Scm polycomb group protein like 2
Transcript NM_006089   
Expression
Putative miRNA Targets on SCML2
3'UTR of SCML2
(miRNA target sites are highlighted)		 
>SCML2|NM_006089|3'UTR
   1 AAAAATGTGTAAGTTTAGATTGGACATAATTCTCAGGTGTACTGTTAACATTTTAATTTAAAAGTATTTCTCTTAGCAGT
  81 TTTTGTTTTGTAGACAGTTCCCATAAAAATATTTTATCAGAATTGCAGAACTGTAGTAACAGTTCAGTCAACTTTGTTTT
 161 TTTCCTGGAGTCACCAACCAGCTTTGGGAGACACAGCCGCCACTCCCCCAGTCTACTTCTTTAAAAAGCATTTAACAGGT
 241 TAGTATTGGCATATTCAAATTGGCAGTTCTTTATGTCTTTTTAAATTTTCATTGTACAGTTTACAAATATACTTAATGTA
 321 GTTAACAGAGAAAAACCTTTGATTTTGGTTAACCTTTATATCTAGAACCAAAACAGCTAAATCCCAAAGGGGAAAATATC
 401 AGGGATTGACAACTTCTATAATTAAATCCATGAGAATTTTTCCTCACTAGAGAATTTAAAGGTGCACCTGTAGATATCAT
 481 CTTTTCTCAGATATTTTGTGTGATACTCTGTGGTGTTCTGTTCATGTTCTATCAGTATATCTAGAAAGGGAATAGCCATA
 561 TAAATTATTTTCCTTTTATTATTTCTCTGTATGTTGTATTTGATCATATTTAAAGGAAAAAAGCAAGCTTATAAGCTTTC
 641 ATGAAGTGTTCTTACCAGTTTTTGATAAATTTTTTAAATTATAGGATAGAATTGTCATTTTATGCAGGAGATATTTATAC
 721 TACGAGGGTTGTTTGGATGGAGTCAGATTAAATTTTTTCAGTGAAATTCCTATTATTTTAAAACTTTCCATATTTTCACT
 801 ACGCTTGGACATTTAACTAGGCATTCTTTTCTTACATCTCTATATGAAGATACCTGTGTCCAAAATTTTTGAAGATATAT
 881 ATTGTATGTGTTTATTCTTCATATGGTACTTTACCATATTTATATATTGTTTTATACCTGTAGGTTTACACACAAGTAAA
 961 TCTTTTTTTTCTTGAATTTAATCTGGCACTTTGCACTGCCACAGAGGTGACGATGAACTATGTATATAGTTAGATGTTTT
1041 GATTTCGTAAAAAATATATGTCCATCGTTTGCTATCACCAGTACCTCTCAGCTTACTCTTCAGGGGATATGAAACAATCT
1121 GTAGATTGGTTTCCATACAGGGAAGTTCTCTGTCCTATGCAATGTTTCTAATTAATTTGCTTAGTTCTGAGCCATTTATT
1201 CTGCTACACTTTGAAAGATATATTAGTTCTGACTTATTGTTTGGGGCTTTATTTTATTTTTATTTTTTTGAGATGGAGTT
1281 TCACTCTTGTTGCCCAGGCTGGAGTGCAATAGCTCGATCTCGGCTCACTGCAACCTCGCCTCCCTGGTTCAAGCAATTCT
1361 CCTGCCTCAGCGATTACAGGAATGCACCACCACGCCCAGCTAATTTTGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCT
1441 GGTCTCAAACTCCTGACCTCAGGTGATCCGCCCACCTCGGCCTTGCAAAATGCTGGGATTACAGGCATGAGCCACCATGC
1521 CCAGCCATGTTTGGGGCTTTATTTTATAAGTTAGAACTTTGAAGAGGAAATGGTGCTATATGTTTATTGTTATTACTTTG
1601 TGTAACTTTGATGTAATGTTTATAAGCTATGAGAATCAGTTATAAAAGTATTAGCCATTTGTTGTAAATGCCAATAAAAT
1681 ATTCACCAGGGGCAAGAATGTACATTTTCTTTTTAGAAAACCAAATGTACTTTAGACATGAATGCAACTATTTAAAGAAT
1761 AGCTTCATTTATGTTATTCCTTACATGTCATAAGATTCTTACTTAAACTTGGTCTTCTTTCAAGTTGTTTGTATGAAGAT
1841 GCTGTACCCACTTGAACAGTCCTCAGGTGTTTACATAAATACTATGTTTTACAGTTTTCATATTTTAAAATATTAATAAA
1921 GTTAATCGCAACGATTCAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuuAGUGUUUACAGGAAUUAUc 5'
             |:|||||| | ||||||: 
Target 5' agtTTACAAATATACTTAATGt 3'
 298 - 319 159.00 -9.20
2 
miRNA  3' cuuAGUGUUUACAGGAAUUAUc 5'
             |:|| |  ||::||:||| 
Target 5' ttcTTACCA--GTTTTTGATAa 3'
 649 - 668 127.00 -5.20
3 
miRNA  3' cuUAGUGUUUACAG---GAAUUauc 5'
            :|||:||:  ||   |||||   
Target 5' atGTCATAAGATTCTTACTTAAact 3'
 1785 - 1809 120.00 -6.51
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1287856462 5 dbSNP
rs746714168 6 dbSNP
rs777686432 6 dbSNP
rs779767255 7 dbSNP
rs1037076724 22 dbSNP
rs763875532 25 dbSNP
rs750358127 26 dbSNP
rs764850013 27 dbSNP
rs1178980010 29 dbSNP
rs756690275 36 dbSNP
rs753348424 44 dbSNP
rs1353691760 62 dbSNP
rs1439918934 75 dbSNP
rs1180174792 97 dbSNP
rs888730791 102 dbSNP
rs779044208 109 dbSNP
rs980454734 116 dbSNP
rs1049101398 125 dbSNP
rs1163043875 127 dbSNP
rs1245136931 145 dbSNP
rs760113781 146 dbSNP
rs1029225973 156 dbSNP
rs1407630192 157 dbSNP
rs757476375 160 dbSNP
rs1329390557 164 dbSNP
rs1376301727 169 dbSNP
rs1286187625 177 dbSNP
rs1311679574 178 dbSNP
rs976374836 185 dbSNP
rs968083586 190 dbSNP
rs1243713649 198 dbSNP
rs1409015837 199 dbSNP
rs372965508 204 dbSNP
rs1358367135 209 dbSNP
rs180990036 211 dbSNP
rs1309823532 212 dbSNP
rs1009298156 215 dbSNP
rs41309701 230 dbSNP
rs956872257 236 dbSNP
rs1240806252 243 dbSNP
rs1390184560 246 dbSNP
rs1163923172 249 dbSNP
rs1019112113 251 dbSNP
rs1369473085 255 dbSNP
rs1473860511 264 dbSNP
rs1474041298 265 dbSNP
rs755995920 268 dbSNP
rs1469180084 275 dbSNP
rs1169226364 283 dbSNP
rs141270670 298 dbSNP
rs1181849080 310 dbSNP
rs1473150504 316 dbSNP
rs1254551179 335 dbSNP
rs944461299 336 dbSNP
rs1449359773 347 dbSNP
rs35441337 347 dbSNP
rs1313158185 354 dbSNP
rs911638936 357 dbSNP
rs547537233 358 dbSNP
rs1216589282 360 dbSNP
rs1209949537 380 dbSNP
rs977761542 382 dbSNP
rs771158742 383 dbSNP
rs754941003 389 dbSNP
rs1050892776 391 dbSNP
rs1199915063 401 dbSNP
rs1406744727 412 dbSNP
rs1350954430 418 dbSNP
rs1290125687 430 dbSNP
rs945019324 437 dbSNP
rs1330454762 440 dbSNP
rs1191994251 442 dbSNP
rs747025506 446 dbSNP
rs1478443033 468 dbSNP
rs775473202 474 dbSNP
rs1386697020 477 dbSNP
rs1158755037 484 dbSNP
rs1303591685 509 dbSNP
rs1465706897 509 dbSNP
rs940763187 510 dbSNP
rs1414723470 516 dbSNP
rs1014929616 518 dbSNP
rs1341038096 529 dbSNP
rs1005333452 530 dbSNP
rs751092134 537 dbSNP
rs1197727060 546 dbSNP
rs1298516850 549 dbSNP
rs1311153837 554 dbSNP
rs1233370468 560 dbSNP
rs981940792 577 dbSNP
rs1487106706 586 dbSNP
rs765893545 592 dbSNP
rs1262994792 634 dbSNP
rs189839852 636 dbSNP
rs926567347 640 dbSNP
rs1265336590 645 dbSNP
rs981057306 646 dbSNP
rs1176882444 648 dbSNP
rs967757442 652 dbSNP
rs1418159613 662 dbSNP
rs1157822066 669 dbSNP
rs914863210 680 dbSNP
rs1401741904 686 dbSNP
rs1004237425 689 dbSNP
rs1207784638 690 dbSNP
rs956426183 692 dbSNP
rs1302784409 695 dbSNP
rs1351036380 696 dbSNP
rs1019165269 705 dbSNP
rs1329449762 714 dbSNP
rs1269713512 717 dbSNP
rs1218418401 719 dbSNP
rs888461715 721 dbSNP
rs1488445670 723 dbSNP
rs1217297576 724 dbSNP
rs1026956258 739 dbSNP
rs1344155851 742 dbSNP
rs1178308905 758 dbSNP
rs1275414828 784 dbSNP
rs1438662206 802 dbSNP
rs1162439726 803 dbSNP
rs1363196437 805 dbSNP
rs369750761 808 dbSNP
rs772886866 818 dbSNP
rs1294774012 835 dbSNP
rs1374074118 844 dbSNP
rs1029251543 853 dbSNP
rs1309471148 856 dbSNP
rs900041945 865 dbSNP
rs995476555 870 dbSNP
rs1225770928 871 dbSNP
rs899190808 874 dbSNP
rs1436012267 879 dbSNP
rs1222997954 883 dbSNP
rs375269126 887 dbSNP
rs764817757 901 dbSNP
rs1004960612 916 dbSNP
rs1198122963 922 dbSNP
rs895896076 928 dbSNP
rs1471288078 936 dbSNP
rs1414311397 950 dbSNP
rs1426451770 960 dbSNP
rs1174898303 971 dbSNP
rs1179889739 971 dbSNP
rs944202288 972 dbSNP
rs1057108109 986 dbSNP
rs1424297540 989 dbSNP
rs1167079814 996 dbSNP
rs1398058550 1011 dbSNP
rs939201694 1012 dbSNP
rs1331452284 1026 dbSNP
rs1455185484 1040 dbSNP
rs16980753 1047 dbSNP
rs1378961373 1055 dbSNP
rs1187396471 1066 dbSNP
rs1045003036 1067 dbSNP
rs1316600769 1071 dbSNP
rs946612241 1098 dbSNP
rs1258864332 1103 dbSNP
rs1439775423 1107 dbSNP
rs1042138650 1114 dbSNP
rs1208337075 1117 dbSNP
rs1236660915 1126 dbSNP
rs1483429247 1127 dbSNP
rs945118339 1142 dbSNP
rs914900287 1147 dbSNP
rs1421315161 1154 dbSNP
rs989123053 1155 dbSNP
rs937966429 1162 dbSNP
rs1421072143 1185 dbSNP
rs926520627 1208 dbSNP
rs981973318 1220 dbSNP
rs1359412524 1225 dbSNP
rs1449125898 1226 dbSNP
rs970528407 1229 dbSNP
rs1015411160 1231 dbSNP
rs775762008 1237 dbSNP
rs1218636105 1245 dbSNP
rs1278889288 1247 dbSNP
rs911653889 1253 dbSNP
rs1220930993 1270 dbSNP
rs1278140335 1276 dbSNP
rs375787319 1280 dbSNP
rs371766566 1283 dbSNP
rs759577069 1284 dbSNP
rs1212733983 1293 dbSNP
rs1260843537 1303 dbSNP
rs1487902179 1306 dbSNP
rs1194362362 1308 dbSNP
rs1476732884 1309 dbSNP
rs1171489536 1310 dbSNP
rs1425366072 1311 dbSNP
rs996854902 1315 dbSNP
rs1175913088 1316 dbSNP
rs1359073265 1319 dbSNP
rs900127592 1321 dbSNP
rs1019811917 1322 dbSNP
rs1328742825 1323 dbSNP
rs746371204 1327 dbSNP
rs1367598619 1335 dbSNP
rs1368563379 1337 dbSNP
rs903375798 1350 dbSNP
rs1236816845 1351 dbSNP
rs1283589705 1356 dbSNP
rs1352647505 1361 dbSNP
rs1301360808 1364 dbSNP
rs1217104965 1366 dbSNP
rs1286179319 1372 dbSNP
rs774342994 1377 dbSNP
rs1041835501 1379 dbSNP
rs1197535258 1389 dbSNP
rs1447760998 1390 dbSNP
rs771010828 1393 dbSNP
rs1455283382 1394 dbSNP
rs1176448816 1396 dbSNP
rs1379329146 1403 dbSNP
rs1419442819 1415 dbSNP
rs945123815 1419 dbSNP
rs1159518913 1421 dbSNP
rs973701744 1435 dbSNP
rs1404161296 1437 dbSNP
rs1322933739 1439 dbSNP
rs749333010 1440 dbSNP
rs1336575051 1455 dbSNP
rs773289344 1468 dbSNP
rs1428310956 1470 dbSNP
rs1390137402 1478 dbSNP
rs1376444739 1479 dbSNP
rs1239426467 1480 dbSNP
rs1281130187 1481 dbSNP
rs778155379 1491 dbSNP
rs1354162497 1502 dbSNP
rs963961737 1505 dbSNP
rs893556066 1515 dbSNP
rs777864513 1520 dbSNP
rs1469382605 1526 dbSNP
rs1196245109 1527 dbSNP
rs769772732 1531 dbSNP
rs1178631529 1533 dbSNP
rs1004847444 1546 dbSNP
rs756340328 1560 dbSNP
rs1182972130 1567 dbSNP
rs1365950539 1580 dbSNP
rs748024365 1602 dbSNP
rs373291576 1605 dbSNP
rs1035755352 1613 dbSNP
rs1463018319 1625 dbSNP
rs1329411011 1629 dbSNP
rs878899318 1637 dbSNP
rs1472334031 1648 dbSNP
rs754921944 1657 dbSNP
rs1399818717 1666 dbSNP
rs949252783 1682 dbSNP
rs1330604451 1686 dbSNP
rs772833475 1689 dbSNP
rs905055188 1700 dbSNP
rs1211975102 1701 dbSNP
rs1216193321 1704 dbSNP
rs141941045 1717 dbSNP
rs781263570 1721 dbSNP
rs982595344 1737 dbSNP
rs1045283011 1747 dbSNP
rs1205925553 1748 dbSNP
rs1441007688 1758 dbSNP
rs952945202 1759 dbSNP
rs1187286981 1767 dbSNP
rs1419138180 1769 dbSNP
rs1476506160 1771 dbSNP
rs920014807 1773 dbSNP
rs1462670195 1776 dbSNP
rs1169824166 1787 dbSNP
rs975848543 1790 dbSNP
rs1400376679 1814 dbSNP
rs964032603 1823 dbSNP
rs946696627 1832 dbSNP
rs1395174436 1833 dbSNP
rs1227900821 1836 dbSNP
rs137959675 1850 dbSNP
rs1286280322 1886 dbSNP
rs5955958 1889 dbSNP
rs967565490 1891 dbSNP
rs1408412114 1901 dbSNP
rs1020912394 1912 dbSNP
rs1052320096 1927 dbSNP
rs1011740769 1928 dbSNP
rs893577255 1932 dbSNP
rs377672178 1933 dbSNP
rs1486922596 1937 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000251900.4 | 3UTR | UCCUCAGGUGUUUACAUAAAUACUAUGUUUUACAGUUUUCAUAUUUUAAAAUAUUAAUAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
134 hsa-miR-4477a Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055843 PLEKHA1 pleckstrin homology domain containing A1 2 10
MIRT061259 AMOTL1 angiomotin like 1 2 4
MIRT071895 BTF3L4 basic transcription factor 3 like 4 2 6
MIRT076933 MLLT6 MLLT6, PHD finger containing 2 2
MIRT078652 ICT1 mitochondrial ribosomal protein L58 2 2
MIRT083633 PRNP prion protein 2 2
MIRT091629 RPL15 ribosomal protein L15 2 4
MIRT107076 PPP6C protein phosphatase 6 catalytic subunit 2 2
MIRT111191 TRIM33 tripartite motif containing 33 2 2
MIRT114515 ARF6 ADP ribosylation factor 6 2 2
MIRT175250 PSAT1 phosphoserine aminotransferase 1 2 4
MIRT175430 ACSL4 acyl-CoA synthetase long chain family member 4 2 2
MIRT178687 FAM102B family with sequence similarity 102 member B 2 2
MIRT189771 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT229450 RPL10 ribosomal protein L10 2 2
MIRT244899 PHF6 PHD finger protein 6 2 2
MIRT249189 AKIRIN1 akirin 1 2 8
MIRT261134 TRIM8 tripartite motif containing 8 2 2
MIRT275561 ZIC5 Zic family member 5 2 4
MIRT275652 ABHD13 abhydrolase domain containing 13 2 2
MIRT288082 UTP18 UTP18, small subunit processome component 2 2
MIRT303605 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT307924 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT316787 FOXC1 forkhead box C1 2 2
MIRT326910 SCML2 Scm polycomb group protein like 2 2 2
MIRT327713 SPIN4 spindlin family member 4 2 2
MIRT331632 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 2
MIRT342506 TMOD3 tropomodulin 3 2 4
MIRT354470 LRRC58 leucine rich repeat containing 58 2 2
MIRT378711 TRIM24 tripartite motif containing 24 2 2
MIRT407462 YDJC YdjC chitooligosaccharide deacetylase homolog 2 2
MIRT408226 SMAD5 SMAD family member 5 2 4
MIRT441824 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT442783 CHD8 chromodomain helicase DNA binding protein 8 2 2
MIRT443184 NHS NHS actin remodeling regulator 2 4
MIRT447615 CUL3 cullin 3 2 2
MIRT450156 DSEL dermatan sulfate epimerase-like 2 2
MIRT454801 NEDD9 neural precursor cell expressed, developmentally down-regulated 9 2 2
MIRT463050 ZNF644 zinc finger protein 644 2 2
MIRT467400 SOCS3 suppressor of cytokine signaling 3 2 2
MIRT468174 SGMS1 sphingomyelin synthase 1 2 2
MIRT468949 RPS14 ribosomal protein S14 2 6
MIRT469835 R3HDM4 R3H domain containing 4 2 2
MIRT470724 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT470902 PLIN3 perilipin 3 2 2
MIRT472467 NAPG NSF attachment protein gamma 2 12
MIRT472602 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT492350 SEMA7A semaphorin 7A (John Milton Hagen blood group) 2 2
MIRT493840 FOXN3 forkhead box N3 2 4
MIRT496318 DOCK9 dedicator of cytokinesis 9 2 2
MIRT500159 CLEC2D C-type lectin domain family 2 member D 2 8
MIRT500535 XPO4 exportin 4 2 4
MIRT503916 FBXL13 F-box and leucine rich repeat protein 13 2 4
MIRT504003 SAT1 spermidine/spermine N1-acetyltransferase 1 2 4
MIRT505647 SHMT1 serine hydroxymethyltransferase 1 2 4
MIRT506574 MIER3 MIER family member 3 2 4
MIRT506945 HS3ST3B1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 2 4
MIRT508196 RPS19 ribosomal protein S19 2 6
MIRT511417 HSPA13 heat shock protein family A (Hsp70) member 13 2 4
MIRT512326 ACTB actin beta 2 4
MIRT515376 RPL7 ribosomal protein L7 2 2
MIRT520422 TUBG1 tubulin gamma 1 2 4
MIRT524844 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT526320 UGT2A1 UDP glucuronosyltransferase family 2 member A1 complex locus 2 2
MIRT526561 UGT2A2 UDP glucuronosyltransferase family 2 member A2 2 2
MIRT528027 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT529874 RBM43 RNA binding motif protein 43 2 2
MIRT530826 CLEC4D C-type lectin domain family 4 member D 2 2
MIRT531334 GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 2 2
MIRT532068 CCNB1 cyclin B1 2 4
MIRT532870 ZNF566 zinc finger protein 566 2 2
MIRT535580 NUP35 nucleoporin 35 2 2
MIRT537644 ERGIC2 ERGIC and golgi 2 2 4
MIRT537725 ELAVL2 ELAV like RNA binding protein 2 2 2
MIRT538894 BRI3BP BRI3 binding protein 2 2
MIRT538945 BMP2K BMP2 inducible kinase 2 2
MIRT540703 PDPK1 3-phosphoinositide dependent protein kinase 1 2 4
MIRT543210 TMEM117 transmembrane protein 117 2 3
MIRT543357 LYRM2 LYR motif containing 2 2 2
MIRT544905 CLSPN claspin 2 2
MIRT545532 ARF3 ADP ribosylation factor 3 2 2
MIRT546446 SMOC1 SPARC related modular calcium binding 1 2 2
MIRT546882 PURB purine rich element binding protein B 2 4
MIRT547440 MED13 mediator complex subunit 13 2 2
MIRT548027 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548673 CRNKL1 crooked neck pre-mRNA splicing factor 1 2 2
MIRT550435 LLGL2 LLGL2, scribble cell polarity complex component 2 2
MIRT551850 RPS3 ribosomal protein S3 2 2
MIRT556072 MRFAP1 Morf4 family associated protein 1 2 2
MIRT556554 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT557132 HOXA13 homeobox A13 2 2
MIRT557875 FEM1B fem-1 homolog B 2 4
MIRT558146 ELK4 ELK4, ETS transcription factor 2 2
MIRT558862 CD2AP CD2 associated protein 2 2
MIRT558884 CCNE1 cyclin E1 2 4
MIRT558907 CBX5 chromobox 5 2 2
MIRT559175 BRAP BRCA1 associated protein 2 2
MIRT560860 GAL3ST3 galactose-3-O-sulfotransferase 3 2 2
MIRT561729 PPIF peptidylprolyl isomerase F 2 2
MIRT564024 CEBPB CCAAT/enhancer binding protein beta 2 2
MIRT564366 TRMT5 tRNA methyltransferase 5 2 2
MIRT564609 ZNF703 zinc finger protein 703 2 2
MIRT565494 AZF1 azoospermia factor 1 2 2
MIRT565577 SLC6A8 solute carrier family 6 member 8 2 2
MIRT566947 LEPROT leptin receptor overlapping transcript 2 2
MIRT567293 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2 2
MIRT567308 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT568048 CHSY1 chondroitin sulfate synthase 1 2 2
MIRT571807 PHF19 PHD finger protein 19 2 2
MIRT609234 RBM23 RNA binding motif protein 23 2 2
MIRT610328 SSX5 SSX family member 5 2 2
MIRT611428 UGT8 UDP glycosyltransferase 8 2 4
MIRT611709 SLFN13 schlafen family member 13 2 2
MIRT612069 CEP135 centrosomal protein 135 2 4
MIRT617676 JRKL JRK like 2 2
MIRT623684 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT635634 PRR15L proline rich 15 like 2 2
MIRT636422 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT637011 GPATCH11 G-patch domain containing 11 2 2
MIRT644150 C4orf3 chromosome 4 open reading frame 3 2 2
MIRT648562 MEMO1 mediator of cell motility 1 2 2
MIRT650752 WNT16 Wnt family member 16 2 2
MIRT651914 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT653556 SLC38A7 solute carrier family 38 member 7 2 2
MIRT692277 XRN2 5'-3' exoribonuclease 2 2 2
MIRT697650 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT703876 ERCC6 ERCC excision repair 6, chromatin remodeling factor 2 2
MIRT704615 CLIP1 CAP-Gly domain containing linker protein 1 2 2
MIRT708562 BBOX1 gamma-butyrobetaine hydroxylase 1 2 2
MIRT709614 KBTBD6 kelch repeat and BTB domain containing 6 2 2
MIRT712955 SGCD sarcoglycan delta 2 2
MIRT713502 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT720239 GPBP1 GC-rich promoter binding protein 1 2 2
MIRT724255 GLUD1 glutamate dehydrogenase 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4477a Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-4477a Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-4477a Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)

Error report submission