miRTarBase - #MIRT328627


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pre-miRNA Information
pre-miRNA hsa-mir-6818   
Genomic Coordinates chr22: 30007049 - 30007113
Description Homo sapiens miR-6818 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6818-5p
Sequence 6| UUGUGUGAGUACAGAGAGCAUC |27
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs763248242 2 dbSNP
rs186621048 3 dbSNP
rs1455267770 12 dbSNP
rs1170462641 19 dbSNP
rs1435853423 22 dbSNP
Putative Targets

Gene Information
Gene Symbol AKIRIN1   
Synonyms C1orf108, STRF2
Description akirin 1
Transcript NM_001136275   
Other Transcripts NM_024595   
Expression
Putative miRNA Targets on AKIRIN1
3'UTR of AKIRIN1
(miRNA target sites are highlighted)		 
>AKIRIN1|NM_001136275|3'UTR
   1 AGCTTTGTCACATATCTGGGTACCAGGTTTGACCTCAAGAGATGGCTGCTGTACACTTTTTGCAACTGGTTTGATGTCAC
  81 ATTTCAGCTCCAACTTTGCATCCTGAGAACACTTAAACGTTTCTGCAGGTCCATTTTATACAACTTGAAAGACCGTAAAA
 161 CTTTCTGGTTGCCACAAGCATATCTTTCTTTTCTGCTCATCCAATAAACAGCTGTGCCCTACTGTGATAGATTTTCCAAA
 241 CAAAAATACCTGGAGCAGCAGTTTAGCAAAATATGCCTTCAGTGGCATTCAACAAATGGAGTTTCCCCAAGCACAGTTCT
 321 GTAAGAAGTGCGTGTGAGAGTGTGTGTATATGTGTGTATGTGTATTTTAAGTTATTATTTGTATTGTGCAAAAATTTTTT
 401 TTTGATCTTGGGGATTCTGGCTGTGAATTTGGTGCACGACAATTATGGTAAAAAAACATTTGCTTGGTCTAAAGAAGATC
 481 ATTAATGTTTTGTGACCATACAAGTTGTAACAGTGGATTGTTTTTATGTGTAGGTATTGTTAAATACAGGGACTGTTTCC
 561 AGGCACAGAATATGAATCGTAAGTTAGGATGGACATTAGATGTGATTATGATGATAAAGCGAAGGTCTGCGGTCCTATAT
 641 CTACAGACACGTGGTGAGAAATTAGAACAAACTGGAGACGGGCCATTGACACATGGACTCTGCCTGGGCATGTTAGGTTA
 721 ATTCTTTGACTCCAAGCCTTAAAATACTCACATGGAGTCAGCGCTCACCTCATTCACACAATTATCATAGAGCTCCCTGG
 801 ACACTGAACCTCTAAAGGGAAAAGGTCTACCCTGGAGCCAGGAGCATCAGGGTTGGCTTGGGAGCATGAGAGGTGAGCCC
 881 AGGGCTAGGCCTGGGCCAGGCCCCGGCAGCACTGCTACTTGGGAGGAGCCACTTCACCTTTGTATTAGTTATTAAAAAAT
 961 ATAATTTGGGCTGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGTCCGAGGCATGCGGATCACTTGAGGTC
1041 AGGAGTTCGAGACCACCCTGGCCAATATGGTGAAACCCCATCTCTACTAAAAATACAACAAAGTTAGCCGGGCGTGGTGG
1121 CAGGCGTCTGTAATCCCAGCTGCTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCTGGAGGTGGCGGTTGCAGTGAGC
1201 ACAGATCATGCCACTGCACTCCAGCCTGGGCAACAAAACGAGACTTCGTCTCAAAAAAAAAAAAAAAACATAGAATTTGG
1281 ATCCTTTGGTCGGGTTCTCCCAAATTCTTTTGAGGTGTCCATGGTCAACTGCTTCAGCTTTGTTTTGGCAACCCCCTGCC
1361 CGAAGTCGCATATAGGCTGTTCTTCACCTTGTTTCCAAGGCTGAGGAACAGAAAGTAGCCTCTGTTTTGAGGAGGTGGAA
1441 GTTAAGTATACATTTATTTTTTACTGTGACTTGTTCAGGACCACATTTTACAAAATGCCTTGTTTCCTTCATTGTTTCTG
1521 GAAAGGAAAGTTCTATTAATATTGTTTTACTTTGAATATAGAATAGTTTTTTTAATTAGGGCTTATTTTGAAAAATTCTG
1601 AGTTTAATTCAAATGTATGCCAATACCTTCCAAAGTAAGGTAATATTCAGAGACAGTTGTTGTGATCAGATGGCTTAGAG
1681 AAATTTCTGGAATATTCACATTCGAAGATTCCTTATTAATGAATGTCTTTGACTTAAATCTAACCAAAAACTGCAACATT
1761 ATTCTTTGTACATTTTCATTATATAGTGTTAACAAGCTTAGTTGCAAACAAATAAAATACTTAAGCTATTTGTTTACCTT
1841 GCCTTCTTAATACTGTGATAATGTTTATTAATTCAAATAACTTATGTGAGAGCTGCTATAACCATTTCCCCAGTTCAACA
1921 TTGCATTGAAAATTTATGGACCTTTAAAAAAAAAAGCCCAACAGTGATTTTTTTTTAATAATTAAAGAATGATTTTACTT
2001 TGTATTTGAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuaCGAGAGACAUGAGUGUGUu 5'
             |||| |   |:||||||| 
Target 5' agcGCTCACCTCATTCACACAa 3'
 760 - 781 159.00 -15.60
2 
miRNA  3' cuacgaGAGACAUGAGUGUGUu 5'
                ||:||   |||||:| 
Target 5' ----agCTTTG---TCACATAt 3'
 1 - 15 133.00 -10.10
3 
miRNA  3' cuacgAGAGAC---AUGAGUGUGuu 5'
               |:||||   ||:|||||:  
Target 5' agaaaTTTCTGGAATATTCACATtc 3'
 1679 - 1703 129.00 -13.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31545746 7 COSMIC
COSN30145779 17 COSMIC
COSN26965687 19 COSMIC
COSN30156457 37 COSMIC
COSN26508010 63 COSMIC
COSN30738798 95 COSMIC
COSN13543023 119 COSMIC
COSN13543028 127 COSMIC
COSN13543029 134 COSMIC
COSN20073987 148 COSMIC
COSN13543030 156 COSMIC
COSN30127298 169 COSMIC
COSN30115523 231 COSMIC
COSN16320331 251 COSMIC
COSN20090208 478 COSMIC
COSN31565531 550 COSMIC
COSN31577313 557 COSMIC
COSN31567716 579 COSMIC
COSN8638278 584 COSMIC
COSN29426741 618 COSMIC
COSN26275725 628 COSMIC
COSN26570012 638 COSMIC
COSN26275726 642 COSMIC
COSN31593556 680 COSMIC
COSN17338062 706 COSMIC
COSN26548990 718 COSMIC
COSN28759440 878 COSMIC
COSN31960221 1126 COSMIC
COSN15661671 1270 COSMIC
COSN19468670 1540 COSMIC
COSN29187760 1660 COSMIC
COSN23079007 1882 COSMIC
COSN28286824 1947 COSMIC
COSN28902517 1956 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1284950958 3 dbSNP
rs1200053251 4 dbSNP
rs1469086107 4 dbSNP
rs780507019 12 dbSNP
rs747365633 15 dbSNP
rs1400659600 16 dbSNP
rs149817455 18 dbSNP
rs371972577 20 dbSNP
rs1488690045 24 dbSNP
rs1164374843 25 dbSNP
rs376888630 27 dbSNP
rs1261708348 35 dbSNP
rs560428173 38 dbSNP
rs1188709025 39 dbSNP
rs772698878 44 dbSNP
rs200624052 45 dbSNP
rs1472265105 47 dbSNP
rs1161356793 51 dbSNP
rs558298991 60 dbSNP
rs1419819253 63 dbSNP
rs766200358 65 dbSNP
rs372089533 66 dbSNP
rs1397496987 67 dbSNP
rs1478401187 68 dbSNP
rs759259138 74 dbSNP
rs767272913 75 dbSNP
rs112358934 76 dbSNP
rs757539408 77 dbSNP
rs765455481 82 dbSNP
rs1458493597 86 dbSNP
rs750499638 88 dbSNP
rs1202629122 89 dbSNP
rs540498199 94 dbSNP
rs1347770852 98 dbSNP
rs981187259 104 dbSNP
rs760096142 115 dbSNP
rs780449239 116 dbSNP
rs1468988178 119 dbSNP
rs1358453850 120 dbSNP
rs1441106556 120 dbSNP
rs1181335080 124 dbSNP
rs1239651735 130 dbSNP
rs747493258 141 dbSNP
rs755304220 142 dbSNP
rs781618322 144 dbSNP
rs1377287744 145 dbSNP
rs747859259 149 dbSNP
rs11547140 155 dbSNP
rs1401203386 156 dbSNP
rs1450237062 165 dbSNP
rs1172774555 166 dbSNP
rs1333574080 167 dbSNP
rs928487643 168 dbSNP
rs934470049 172 dbSNP
rs574293996 174 dbSNP
rs769418667 175 dbSNP
rs1164923654 180 dbSNP
rs748518608 181 dbSNP
rs761309826 198 dbSNP
rs772754035 201 dbSNP
rs1200938974 203 dbSNP
rs748814525 205 dbSNP
rs1457935070 212 dbSNP
rs1177692429 213 dbSNP
rs914473781 217 dbSNP
rs1247785583 218 dbSNP
rs770413746 219 dbSNP
rs1199455295 220 dbSNP
rs1377034980 230 dbSNP
rs1341071320 231 dbSNP
rs1467996617 234 dbSNP
rs1401697069 241 dbSNP
rs1223950474 242 dbSNP
rs774157040 246 dbSNP
rs759510287 250 dbSNP
rs145873918 253 dbSNP
rs561299381 256 dbSNP
rs149002326 257 dbSNP
rs1387455865 258 dbSNP
rs1263326358 265 dbSNP
rs1043695370 269 dbSNP
rs1308929582 272 dbSNP
rs1221837278 273 dbSNP
rs536186747 275 dbSNP
rs932776346 282 dbSNP
rs1051117090 283 dbSNP
rs891322540 285 dbSNP
rs1266638197 297 dbSNP
rs1004365582 301 dbSNP
rs1486738732 308 dbSNP
rs1016278230 322 dbSNP
rs898714386 329 dbSNP
rs564050687 331 dbSNP
rs777067715 333 dbSNP
rs1426957995 341 dbSNP
rs144507104 347 dbSNP
rs1193074906 348 dbSNP
rs969705126 349 dbSNP
rs1167080521 359 dbSNP
rs1217391360 365 dbSNP
rs1385944057 367 dbSNP
rs1002654594 372 dbSNP
rs374677838 372 dbSNP
rs772898881 375 dbSNP
rs1301562492 378 dbSNP
rs1224921602 384 dbSNP
rs1162243581 390 dbSNP
rs1343135075 392 dbSNP
rs1282138920 395 dbSNP
rs1400062911 395 dbSNP
rs1343005204 408 dbSNP
rs192501029 415 dbSNP
rs1453509566 420 dbSNP
rs1360060219 436 dbSNP
rs759841694 438 dbSNP
rs546514050 439 dbSNP
rs184426490 443 dbSNP
rs535699624 447 dbSNP
rs1487681427 448 dbSNP
rs1288650890 450 dbSNP
rs1184650970 451 dbSNP
rs1360908301 452 dbSNP
rs114649333 455 dbSNP
rs776238261 457 dbSNP
rs778157728 457 dbSNP
rs921296354 468 dbSNP
rs1262112133 472 dbSNP
rs1316634225 477 dbSNP
rs532618590 478 dbSNP
rs1382115599 479 dbSNP
rs538264734 482 dbSNP
rs1339160950 493 dbSNP
rs1450896293 499 dbSNP
rs558210569 500 dbSNP
rs773631432 501 dbSNP
rs578060972 502 dbSNP
rs759045345 504 dbSNP
rs912623352 508 dbSNP
rs1467262461 512 dbSNP
rs1371359880 514 dbSNP
rs1318626204 524 dbSNP
rs1168284064 529 dbSNP
rs1037164335 535 dbSNP
rs534394061 535 dbSNP
rs1185208705 536 dbSNP
rs1459813195 551 dbSNP
rs554118337 552 dbSNP
rs1263004864 553 dbSNP
rs898657016 559 dbSNP
rs1249147507 565 dbSNP
rs995808058 569 dbSNP
rs1322866525 576 dbSNP
rs1044656488 578 dbSNP
rs1185687300 579 dbSNP
rs188119069 580 dbSNP
rs1332354013 590 dbSNP
rs1393327563 598 dbSNP
rs753263543 604 dbSNP
rs74067034 609 dbSNP
rs191787539 615 dbSNP
rs1181794169 621 dbSNP
rs955779891 622 dbSNP
rs1382771381 631 dbSNP
rs4147753 638 dbSNP
rs1384349370 642 dbSNP
rs754034280 644 dbSNP
rs1439218921 645 dbSNP
rs1021496742 646 dbSNP
rs968947234 649 dbSNP
rs143669799 651 dbSNP
rs1244392456 652 dbSNP
rs954063283 660 dbSNP
rs116861301 662 dbSNP
rs775066608 680 dbSNP
rs532927177 681 dbSNP
rs377493051 684 dbSNP
rs1338322999 685 dbSNP
rs1306561225 686 dbSNP
rs1387486907 693 dbSNP
rs986734273 695 dbSNP
rs1304924490 703 dbSNP
rs1422704604 704 dbSNP
rs760324852 707 dbSNP
rs1364834626 711 dbSNP
rs1383043817 716 dbSNP
rs1471001494 717 dbSNP
rs1451336190 721 dbSNP
rs546675938 726 dbSNP
rs912640802 732 dbSNP
rs750607210 734 dbSNP
rs763803371 744 dbSNP
rs1375520316 747 dbSNP
rs1224288366 752 dbSNP
rs1306147498 753 dbSNP
rs1287291676 760 dbSNP
rs868408964 763 dbSNP
rs1037516966 764 dbSNP
rs1260414648 765 dbSNP
rs1234200798 773 dbSNP
rs1205300064 784 dbSNP
rs1281482047 786 dbSNP
rs1445330351 788 dbSNP
rs920136022 795 dbSNP
rs1264030141 796 dbSNP
rs560047034 798 dbSNP
rs1461034666 800 dbSNP
rs758157396 803 dbSNP
rs1402288467 805 dbSNP
rs1201912229 807 dbSNP
rs1157674419 813 dbSNP
rs931456665 815 dbSNP
rs779757139 820 dbSNP
rs746961941 823 dbSNP
rs1044688999 826 dbSNP
rs745767804 827 dbSNP
rs1470514970 828 dbSNP
rs1177169001 830 dbSNP
rs4147752 832 dbSNP
rs1284050214 833 dbSNP
rs549270668 838 dbSNP
rs753657279 841 dbSNP
rs1325945704 843 dbSNP
rs1261424531 846 dbSNP
rs1223054894 848 dbSNP
rs569203358 850 dbSNP
rs1318681727 854 dbSNP
rs1270746508 866 dbSNP
rs1406452721 867 dbSNP
rs1324574063 870 dbSNP
rs1468957193 872 dbSNP
rs1453020780 883 dbSNP
rs1164289278 895 dbSNP
rs1173802428 896 dbSNP
rs1468882662 897 dbSNP
rs1419574660 903 dbSNP
rs1002549839 905 dbSNP
rs1355781572 914 dbSNP
rs538225984 922 dbSNP
rs1442231801 924 dbSNP
rs1056777103 927 dbSNP
rs891451111 933 dbSNP
rs551523490 934 dbSNP
rs866220882 938 dbSNP
rs768648325 945 dbSNP
rs1275242390 955 dbSNP
rs1225183477 962 dbSNP
rs761566142 968 dbSNP
rs904378575 970 dbSNP
rs1269452712 971 dbSNP
rs995941646 972 dbSNP
rs571711974 976 dbSNP
rs1322492236 977 dbSNP
rs1334334608 987 dbSNP
rs78361436 990 dbSNP
rs1330326222 991 dbSNP
rs1028879729 992 dbSNP
rs1275330060 1005 dbSNP
rs1419511071 1014 dbSNP
rs1438489528 1017 dbSNP
rs1203883015 1018 dbSNP
rs954594060 1019 dbSNP
rs1183325173 1026 dbSNP
rs554249990 1027 dbSNP
rs1234756631 1028 dbSNP
rs768239092 1037 dbSNP
rs567486130 1049 dbSNP
rs1200676710 1050 dbSNP
rs1223101017 1058 dbSNP
rs1019646119 1059 dbSNP
rs1312678698 1061 dbSNP
rs1479624830 1065 dbSNP
rs145060641 1066 dbSNP
rs1373615518 1071 dbSNP
rs1280923170 1072 dbSNP
rs972866622 1076 dbSNP
rs1353390985 1078 dbSNP
rs1421171179 1079 dbSNP
rs919984073 1087 dbSNP
rs1410081211 1095 dbSNP
rs556420791 1096 dbSNP
rs980235061 1097 dbSNP
rs1368692566 1098 dbSNP
rs1406710606 1110 dbSNP
rs1410518475 1111 dbSNP
rs1175684180 1114 dbSNP
rs1469731292 1115 dbSNP
rs1201626391 1118 dbSNP
rs747662280 1123 dbSNP
rs1289425127 1125 dbSNP
rs1317279311 1126 dbSNP
rs531906583 1127 dbSNP
rs576364144 1130 dbSNP
rs1402821102 1131 dbSNP
rs772774955 1136 dbSNP
rs762601872 1148 dbSNP
rs1349451991 1160 dbSNP
rs373085349 1161 dbSNP
rs1340282827 1163 dbSNP
rs1303071354 1167 dbSNP
rs1214129820 1170 dbSNP
rs938952068 1173 dbSNP
rs765193748 1182 dbSNP
rs1057385374 1183 dbSNP
rs1361610822 1184 dbSNP
rs1223893335 1186 dbSNP
rs891486862 1188 dbSNP
rs945684101 1189 dbSNP
rs1489974936 1215 dbSNP
rs1195735178 1220 dbSNP
rs548429793 1229 dbSNP
rs1475527851 1231 dbSNP
rs1018805173 1235 dbSNP
rs1166897850 1236 dbSNP
rs1042830108 1240 dbSNP
rs1213324043 1241 dbSNP
rs1328062334 1242 dbSNP
rs1387785992 1245 dbSNP
rs1263300991 1246 dbSNP
rs544187602 1249 dbSNP
rs1164156771 1251 dbSNP
rs1348732853 1253 dbSNP
rs1364645364 1253 dbSNP
rs542393644 1253 dbSNP
rs1364865532 1254 dbSNP
rs1287503682 1265 dbSNP
rs1430377644 1266 dbSNP
rs148712732 1269 dbSNP
rs80030342 1269 dbSNP
rs1205145881 1270 dbSNP
rs1384902368 1270 dbSNP
rs1320041876 1271 dbSNP
rs1327309839 1272 dbSNP
rs904241579 1280 dbSNP
rs1254929566 1284 dbSNP
rs995972877 1292 dbSNP
rs184048395 1293 dbSNP
rs1294056215 1304 dbSNP
rs890279424 1307 dbSNP
rs138842575 1313 dbSNP
rs1338989890 1315 dbSNP
rs1450762672 1316 dbSNP
rs539911811 1317 dbSNP
rs1401706190 1322 dbSNP
rs1298832582 1330 dbSNP
rs1463529292 1331 dbSNP
rs772340850 1335 dbSNP
rs1168212162 1347 dbSNP
rs370377538 1352 dbSNP
rs1246771774 1353 dbSNP
rs1385597708 1355 dbSNP
rs1185152270 1360 dbSNP
rs1291735296 1362 dbSNP
rs1357916287 1363 dbSNP
rs776059665 1368 dbSNP
rs1285408570 1369 dbSNP
rs761113062 1373 dbSNP
rs961421470 1374 dbSNP
rs879628230 1386 dbSNP
rs1340100736 1388 dbSNP
rs529077134 1396 dbSNP
rs1307970215 1399 dbSNP
rs764734458 1403 dbSNP
rs4433383 1406 dbSNP
rs575018785 1412 dbSNP
rs1027081886 1413 dbSNP
rs1394390176 1423 dbSNP
rs1306146781 1425 dbSNP
rs1429061150 1439 dbSNP
rs952735454 1441 dbSNP
rs1165249661 1444 dbSNP
rs1422514153 1448 dbSNP
rs1367591814 1450 dbSNP
rs1192064223 1452 dbSNP
rs189132319 1474 dbSNP
rs1245766042 1483 dbSNP
rs1247844455 1500 dbSNP
rs1180765505 1503 dbSNP
rs1490659653 1505 dbSNP
rs1445982284 1519 dbSNP
rs1183635815 1527 dbSNP
rs1384605711 1534 dbSNP
rs754371687 1536 dbSNP
rs1294502074 1539 dbSNP
rs927477377 1548 dbSNP
rs761817917 1551 dbSNP
rs938817746 1555 dbSNP
rs993116680 1557 dbSNP
rs1385411428 1559 dbSNP
rs1399860493 1567 dbSNP
rs913450415 1567 dbSNP
rs1241412844 1574 dbSNP
rs1318815767 1597 dbSNP
rs562760764 1600 dbSNP
rs1287827172 1601 dbSNP
rs745992756 1601 dbSNP
rs376008884 1603 dbSNP
rs561895518 1603 dbSNP
rs796897292 1606 dbSNP
rs1304868146 1609 dbSNP
rs1384912792 1611 dbSNP
rs1338713634 1615 dbSNP
rs1043081585 1616 dbSNP
rs181772912 1623 dbSNP
rs904284150 1624 dbSNP
rs931766354 1628 dbSNP
rs1241812113 1636 dbSNP
rs1409238007 1637 dbSNP
rs1050122134 1639 dbSNP
rs1480475816 1642 dbSNP
rs1271754137 1647 dbSNP
rs372339674 1653 dbSNP
rs796848707 1656 dbSNP
rs11547137 1657 dbSNP
rs1036295790 1658 dbSNP
rs897704260 1668 dbSNP
rs1350436570 1669 dbSNP
rs1207211155 1670 dbSNP
rs1348820076 1673 dbSNP
rs1203731815 1676 dbSNP
rs12091652 1679 dbSNP
rs1325733162 1684 dbSNP
rs1318394745 1687 dbSNP
rs1285159731 1701 dbSNP
rs994185484 1704 dbSNP
rs1027441749 1705 dbSNP
rs1383636001 1709 dbSNP
rs1386084547 1710 dbSNP
rs1319454791 1713 dbSNP
rs952680537 1721 dbSNP
rs1001646764 1733 dbSNP
rs1034414960 1741 dbSNP
rs1477999109 1742 dbSNP
rs1374073735 1756 dbSNP
rs1195863946 1765 dbSNP
rs765318782 1768 dbSNP
rs1421478820 1769 dbSNP
rs1261367353 1773 dbSNP
rs1183945595 1784 dbSNP
rs993376371 1793 dbSNP
rs913491855 1810 dbSNP
rs1229412177 1823 dbSNP
rs1364264019 1824 dbSNP
rs1362740846 1827 dbSNP
rs1469471004 1829 dbSNP
rs1452950256 1843 dbSNP
rs750612601 1848 dbSNP
rs758588199 1853 dbSNP
rs1407780161 1861 dbSNP
rs1408645709 1867 dbSNP
rs1413409640 1877 dbSNP
rs967994693 1884 dbSNP
rs1336245539 1886 dbSNP
rs551656847 1895 dbSNP
rs571511719 1899 dbSNP
rs928975937 1901 dbSNP
rs1241606993 1906 dbSNP
rs1393162510 1921 dbSNP
rs1209589008 1930 dbSNP
rs931632115 1936 dbSNP
rs1273689082 1939 dbSNP
rs185740979 1940 dbSNP
rs1339923904 1943 dbSNP
rs1246361724 1946 dbSNP
rs1282056044 1946 dbSNP
rs1296623446 1946 dbSNP
rs911614486 1946 dbSNP
rs1335653356 1956 dbSNP
rs1049231276 1960 dbSNP
rs1036567986 1968 dbSNP
rs547546697 1968 dbSNP
rs944565210 1968 dbSNP
rs941613134 1977 dbSNP
rs1324647230 1978 dbSNP
rs1223756164 1979 dbSNP
rs999917 1980 dbSNP
rs1482004276 1981 dbSNP
rs1197015100 1982 dbSNP
rs894663499 1999 dbSNP
rs1048992691 2002 dbSNP
rs529339397 2005 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 79647.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cuaCGAGAGACAUGAGUGUGUu 5'
             |||| |   |:||||||| 
Target 5' --cGCUCACCUCAUUCACACAa 3'
 		1 - 20
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000432648.3 | 3UTR | CGCUCACCUCAUUCACACAAUUAUCAUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
140 hsa-miR-6818-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT071796 RNF11 ring finger protein 11 2 2
MIRT077120 NKIRAS2 NFKB inhibitor interacting Ras like 2 2 4
MIRT079951 RNF138 ring finger protein 138 2 2
MIRT102968 EN2 engrailed homeobox 2 2 4
MIRT115694 MGRN1 mahogunin ring finger 1 2 2
MIRT121074 FGFRL1 fibroblast growth factor receptor like 1 2 2
MIRT143171 GLYR1 glyoxylate reductase 1 homolog 2 2
MIRT145635 LASP1 LIM and SH3 protein 1 2 2
MIRT282026 ARID3B AT-rich interaction domain 3B 2 6
MIRT301684 EP300 E1A binding protein p300 2 2
MIRT328627 AKIRIN1 akirin 1 2 2
MIRT340977 IPO5 importin 5 2 2
MIRT371401 STC2 stanniocalcin 2 2 2
MIRT378008 TMED7 transmembrane p24 trafficking protein 7 2 4
MIRT445185 CCDC88C coiled-coil domain containing 88C 2 2
MIRT447120 DUSP16 dual specificity phosphatase 16 2 2
MIRT449153 SORCS2 sortilin related VPS10 domain containing receptor 2 2 2
MIRT450200 ABHD15 abhydrolase domain containing 15 2 2
MIRT453853 ZNF12 zinc finger protein 12 2 2
MIRT459077 LSM1 LSM1 homolog, mRNA degradation associated 2 2
MIRT461304 MRPS27 mitochondrial ribosomal protein S27 2 2
MIRT464137 VPS28 VPS28, ESCRT-I subunit 2 2
MIRT468114 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT471401 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT478220 DDX52 DExD-box helicase 52 2 2
MIRT479695 CCNT1 cyclin T1 2 2
MIRT479779 CCND1 cyclin D1 2 2
MIRT484980 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 8
MIRT485016 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 8
MIRT485034 TMEM189 transmembrane protein 189 2 8
MIRT485221 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT490143 TERF2IP TERF2 interacting protein 2 6
MIRT508908 DOK6 docking protein 6 2 6
MIRT513877 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 2 4
MIRT515966 C9orf156 tRNA methyltransferase O 2 4
MIRT517892 CHAF1B chromatin assembly factor 1 subunit B 2 4
MIRT518660 CLVS2 clavesin 2 2 4
MIRT520027 YOD1 YOD1 deubiquitinase 2 6
MIRT523884 EPHA5 EPH receptor A5 2 4
MIRT529237 PORCN porcupine O-acyltransferase 2 2
MIRT535337 PFN1 profilin 1 2 2
MIRT537532 EZR ezrin 2 2
MIRT537695 ELOVL6 ELOVL fatty acid elongase 6 2 2
MIRT538494 CLOCK clock circadian regulator 2 2
MIRT539140 ARHGAP35 Rho GTPase activating protein 35 2 2
MIRT541380 CDKN1A cyclin dependent kinase inhibitor 1A 2 2
MIRT545018 PLP1 proteolipid protein 1 2 2
MIRT547732 KIF23 kinesin family member 23 2 4
MIRT548257 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT550372 MYLK3 myosin light chain kinase 3 2 2
MIRT551867 TMEM47 transmembrane protein 47 2 2
MIRT552289 SNAP29 synaptosome associated protein 29 2 2
MIRT552902 VSNL1 visinin like 1 2 8
MIRT552990 VAMP4 vesicle associated membrane protein 4 2 4
MIRT554729 RHOC ras homolog family member C 2 2
MIRT555301 PPP3CB protein phosphatase 3 catalytic subunit beta 2 2
MIRT556832 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT557523 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT558238 EDA2R ectodysplasin A2 receptor 2 2
MIRT558920 CBX1 chromobox 1 2 2
MIRT559198 BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 2 2
MIRT559611 AMER1 APC membrane recruitment protein 1 2 2
MIRT559769 URGCP-MRPS24 URGCP-MRPS24 readthrough 2 4
MIRT564648 ZNF487P zinc finger protein 487 1 1
MIRT565856 NHS NHS actin remodeling regulator 2 2
MIRT569044 ZNF655 zinc finger protein 655 2 2
MIRT569154 SIGMAR1 sigma non-opioid intracellular receptor 1 2 2
MIRT569166 DMD dystrophin 2 2
MIRT569205 CASZ1 castor zinc finger 1 2 2
MIRT569264 BRWD3 bromodomain and WD repeat domain containing 3 2 2
MIRT569431 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT569476 CTSE cathepsin E 2 2
MIRT570232 NCAN neurocan 2 2
MIRT570519 SHH sonic hedgehog 2 2
MIRT570680 FZD5 frizzled class receptor 5 2 2
MIRT572161 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT575142 Cd93 CD93 antigen 2 3
MIRT575644 Mitf microphthalmia-associated transcription factor 2 3
MIRT575653 Synpo synaptopodin 2 4
MIRT576375 Runx1t1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 2 2
MIRT576388 Fhl2 four and a half LIM domains 2 2 3
MIRT576413 Pla2g16 phospholipase A2, group XVI 2 2
MIRT576697 Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 2 3
MIRT606872 CHST11 carbohydrate sulfotransferase 11 2 4
MIRT606940 GFRA1 GDNF family receptor alpha 1 2 6
MIRT607025 ZEB1 zinc finger E-box binding homeobox 1 2 2
MIRT607028 PPY pancreatic polypeptide 2 4
MIRT607081 MITF melanogenesis associated transcription factor 2 3
MIRT607769 HS6ST3 heparan sulfate 6-O-sulfotransferase 3 2 6
MIRT607881 SATB1 SATB homeobox 1 2 2
MIRT607996 BTBD9 BTB domain containing 9 2 2
MIRT608124 TSC22D2 TSC22 domain family member 2 2 2
MIRT608132 TGFBR2 transforming growth factor beta receptor 2 2 2
MIRT608209 ADAT2 adenosine deaminase, tRNA specific 2 2 2
MIRT608337 SPN sialophorin 2 2
MIRT608416 SYNPO synaptopodin 2 5
MIRT608459 CD93 CD93 molecule 2 3
MIRT608555 SBK1 SH3 domain binding kinase 1 2 6
MIRT608585 PPP2R1B protein phosphatase 2 scaffold subunit Abeta 2 4
MIRT608785 JAKMIP2 janus kinase and microtubule interacting protein 2 2 4
MIRT608791 CDH12 cadherin 12 2 2
MIRT608816 ONECUT3 one cut homeobox 3 2 6
MIRT608876 CNTF ciliary neurotrophic factor 2 6
MIRT608881 CLIC6 chloride intracellular channel 6 2 2
MIRT608894 ZNF860 zinc finger protein 860 2 2
MIRT608954 GIMAP1 GTPase, IMAP family member 1 2 4
MIRT609007 HPS3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 2 3
MIRT609045 INVS inversin 2 4
MIRT619037 CASS4 Cas scaffolding protein family member 4 2 2
MIRT625226 RPSAP58 ribosomal protein SA pseudogene 58 2 4
MIRT625545 GABRB2 gamma-aminobutyric acid type A receptor beta2 subunit 2 2
MIRT627333 TTLL7 tubulin tyrosine ligase like 7 2 2
MIRT627954 NLK nemo like kinase 2 2
MIRT629280 UNC13A unc-13 homolog A 2 2
MIRT634982 TNFAIP8 TNF alpha induced protein 8 2 2
MIRT646129 C1orf147 chromosome 1 open reading frame 147 2 2
MIRT646370 SLC22A6 solute carrier family 22 member 6 2 2
MIRT652743 TGFA transforming growth factor alpha 2 4
MIRT653984 SEMA6A semaphorin 6A 2 2
MIRT660038 C15orf61 chromosome 15 open reading frame 61 2 2
MIRT663504 NKAPL NFKB activating protein like 2 4
MIRT667117 OCIAD2 OCIA domain containing 2 2 2
MIRT683747 C3orf36 chromosome 3 open reading frame 36 2 2
MIRT683922 SLC43A3 solute carrier family 43 member 3 2 2
MIRT684101 LHFP LHFPL tetraspan subfamily member 6 2 2
MIRT684224 FGF14 fibroblast growth factor 14 2 2
MIRT685560 SRD5A3 steroid 5 alpha-reductase 3 2 2
MIRT687408 NRXN1 neurexin 1 2 2
MIRT687467 NHSL2 NHS like 2 2 2
MIRT687695 LEPREL1 prolyl 3-hydroxylase 2 1 1
MIRT688094 GLRA3 glycine receptor alpha 3 2 2
MIRT688255 FHL2 four and a half LIM domains 2 2 3
MIRT688851 CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 2 2
MIRT700293 RABGEF1 RAB guanine nucleotide exchange factor 1 2 2
MIRT704679 CHST2 carbohydrate sulfotransferase 2 2 2
MIRT706392 PPID peptidylprolyl isomerase D 2 2
MIRT707388 SLC35F6 solute carrier family 35 member F6 2 2
MIRT707509 PPP1R16B protein phosphatase 1 regulatory subunit 16B 2 2
MIRT709808 AR androgen receptor 2 2
MIRT715491 MAZ MYC associated zinc finger protein 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6818-5p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-miR-6818-5p Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-6818-5p Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)

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