miRTarBase - #MIRT334112


—
pre-miRNA Information
pre-miRNA hsa-mir-3678   
Genomic Coordinates chr17: 75406069 - 75406162
Description Homo sapiens miR-3678 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3678-3p
Sequence 69| CUGCAGAGUUUGUACGGACCGG |90
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs988363493 1 dbSNP
rs753118178 5 dbSNP
rs1424776090 14 dbSNP
rs1475188526 15 dbSNP
rs1163369708 17 dbSNP
rs1174219930 19 dbSNP
rs915488824 20 dbSNP
rs1273558782 21 dbSNP
rs755095016 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PPP6R3   
Synonyms C11orf23, PP6R3, SAP190, SAPL, SAPLa, SAPS3
Description protein phosphatase 6 regulatory subunit 3
Transcript NM_001164160   
Other Transcripts NM_001164161 , NM_001164162 , NM_001164163 , NM_001164164 , NM_018312   
Expression
Putative miRNA Targets on PPP6R3
3'UTR of PPP6R3
(miRNA target sites are highlighted)		 
>PPP6R3|NM_001164160|3'UTR
   1 CGGGTGACGTCTGCTGCTGCTGACTGAGGACTGCAGACCGCCACCACTCAGGGGCTCTGGAGGGGTCAGCTGGAGCCCAC
  81 CAAGCTGTCACTGCTGCACTCACTCTGCAAGGGATCAGGACCAGCAACCTTTATATTCTAGATTCTAAGACATTGTACAG
 161 AGAAATTCAGAAGTGTAAAAATATTGCACATTGACAAATACCAAGAATTTTTGCGTATGTTTATATTGTATTGTTCTAAA
 241 TAATGGGTAGCCTGTGAAATAAGATCTTGCCACCCATGTAATAATAGTAGTAATACTATAGTTAAAATGGCTGTAAGAAT
 321 AGTTTTATAAAAGTGAATACACAGATCTATTGTATTTGAAACATAACTTTGACAATTATTAGTGTGACCAAAGTATTAGG
 401 CGGTTTTCATACATTTTTCACCTTGTACAAAATTATGAATTCATTTTTCCTCCAGGCCGACAAGGAGTTGTAGAATGAAA
 481 ATGCCCTCTAAGTGTTATTTTGGTTGTTCTAACTTACAAAAGTGATTTTGAATAAGAAATATTTGGTGTTCTTTTTATAA
 561 CCAGTTTTTGATTGGTAATTGTTTTCTGTATTGTTTAAAACGGATCAAAAATGTAAGTCTATTGGTAGAGATTAAGTAAA
 641 GTATTTATTGCTACATCATAGTTGATAAATTGATGTTATCGTAAAGCCATATGTTCTGTTCAAGTCTTGTTTGCTTGAAA
 721 TGATTATTCCTACAAGTGAAACACTAGACTATTTGGAGTGTATATGGCTTGTGTTTTGGGATTTTTTTTTTTTTTTTTTG
 801 GCTTTTGTTTTTGTTTGTTTTTTTGTTTCATTTGGTAGTTCATCTGCCTTTTAACCCATTCACCAAAATTTACCTTGTTA
 881 ACAAGCATCACCAATGAACATTTCAGAGCAATCTGCATATTTAACAGACCTAAAATAAATCCTATTAGGCAAGTCAGTTG
 961 AAAATGCTCGTGCTGCTAATGGAATTAGAGTGCGTTCATTTTACAGGCTAGTATTTTAAAAGTAGAAATCAAAATCTGGC
1041 ACCGAAGCATGCTAATTGTTTACTGTACCTTGTGAGGTTTTCACTCATAAATTTAAACCAGTGTATTTTTTTAGAACTGG
1121 TTTGTGTATATATATAGTGATTATGGATACTAATTCAATGTAATTTATAATTTTCTATGTCAATACAAAAATACATCACA
1201 GCCTTCTCAAACAGCTCAAGCAATATATTGTATATTGCCATATCGTCTGGTGAAAGGGTTAAATTACTTCACCTCTTGCA
1281 CTTTTAGATGCAAATCAGTTTTTCATTTCTGTAATAGAAAATTATTCACGTATTTTTACATCATTTGTTTTTCCTGACCA
1361 GTATTTAAAACCAAAAGGATATTCTGAAAAATGGCCAACAATTTTTTTAGAAGTAGCATCCCAAGCAGCGTGCCTAAACA
1441 TTACATTGCATATGGAAATAAAAGAATCAAACGTCTAATGCCTTATTATTTCTGATTTCCTTTTTCATTTTAAGTGGTGT
1521 GGAGATTCCAGCACTCCCAGGACAGTGGAGTCAGCAGTAAGCCCTGGGACAGGTGGCAAGGGTGGGTCCCTTGACCTTTG
1601 CACGCCTCCTCAGGAACCCCCTTTCCCGGGTGAGCCCCTCTCTGAAGAGACTGTCCTTGGGCCTCCTCTGGAAGCAGCAC
1681 CCCCAGAGGACAGGGCTCCTCCTGCTTGCCTCAGGGCTGCCTGACTTGAATGGCGTTGGACCTCGGGGATTACTGGTAGA
1761 TAATATGCTCTGGTCTCGCCTGGTGGTGAGTTTTGCCAGCCATGGCCAGGGTTTGGCTCCACTGGTGGCACACGTGGCCT
1841 CCGTGGTATGGACCTGGTGGCTTCTCCATCCCACTGTGGCCTCTGTGGTATGGACCTGGTGGCTTCTCCATCCTACCCAA
1921 GGTAACAGTGTCTTGCTTCATCCCACTGACTGCTGGGAGAGAGCCTCTGGGACTTTTCTTTGGGGCATCATTTTGTTTTG
2001 TCTTTCGTAGCAGGGAAAGGATATGACAATGGGGAGGACAGTTCTTTTGGAGGTTGGAGGGGCCAAGCCAAGGACAGGAG
2081 CAAGTGTGCCCTCATTTTGTTTCTACTTTTAATTTCTGTGTGTTGGCCATACTGAATTATGAGACTAACAGATGTCTACA
2161 ATACAATACCTGTATTCAAAATAACAAAAATAAAGCCTGATTCTTTGTTTCTAGAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggccaGGCAUGUUUGAGACGUc 5'
               |:| ||  |||||||| 
Target 5' cactgCTGCACTCACTCTGCAa 3'
 89 - 110 157.00 -16.70
2 
miRNA  3' ggCCAGGCAUGUUUGAGACGUc 5'
            ||||| | ::| ||:|||| 
Target 5' tgGGTCCCT-TGACCTTTGCAc 3'
 1583 - 1603 147.00 -13.82
3 
miRNA  3' ggccAGGCAUGUUUGAGACGUc 5'
              || | :|||  |||||| 
Target 5' cattTCAGAGCAA--TCTGCAt 3'
 899 - 918 129.00 -6.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26990237 2 COSMIC
COSN26990235 3 COSMIC
COSN13345689 10 COSMIC
COSN26990232 41 COSMIC
COSN30185739 47 COSMIC
COSN31593262 67 COSMIC
COSN30098657 76 COSMIC
COSN31524154 97 COSMIC
COSN21234654 195 COSMIC
COSN31606783 209 COSMIC
COSN31571853 211 COSMIC
COSN31592674 222 COSMIC
COSN30540801 305 COSMIC
COSN31565921 307 COSMIC
COSN22871829 321 COSMIC
COSN27172450 493 COSMIC
COSN19221244 564 COSMIC
COSN20108451 640 COSMIC
COSN25644332 774 COSMIC
COSN19367656 799 COSMIC
COSN20108453 800 COSMIC
COSN28647806 831 COSMIC
COSN28815310 1088 COSMIC
COSN31532511 1113 COSMIC
COSN31555369 1127 COSMIC
COSN32061626 1192 COSMIC
COSN8584613 1250 COSMIC
COSN20077199 1251 COSMIC
COSN26562014 1259 COSMIC
COSN31486786 1271 COSMIC
COSN21430448 1297 COSMIC
COSN31605056 1300 COSMIC
COSN31608138 1301 COSMIC
COSN30167446 1310 COSMIC
COSN8584614 1325 COSMIC
COSN5828647 1337 COSMIC
COSN22239386 1343 COSMIC
COSN21853849 1375 COSMIC
COSN30110852 1389 COSMIC
COSN30110856 1397 COSMIC
COSN30539964 1429 COSMIC
COSN31586232 1473 COSMIC
COSN19659226 1489 COSMIC
COSN30133311 1495 COSMIC
COSM5675568 1539 COSMIC
COSM1729910 1557 COSMIC
COSN22920867 1568 COSMIC
COSN19659127 1609 COSMIC
COSN30710539 1752 COSMIC
COSN1080393 1784 COSMIC
COSN20092386 1873 COSMIC
COSN20092387 1885 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs139831773 2 dbSNP
rs370939332 3 dbSNP
rs1165636607 4 dbSNP
rs1406420739 8 dbSNP
rs761090518 9 dbSNP
rs766846099 10 dbSNP
rs1365104844 11 dbSNP
rs750146446 11 dbSNP
rs764864994 11 dbSNP
rs754323376 14 dbSNP
rs754481243 18 dbSNP
rs758104482 20 dbSNP
rs980070858 24 dbSNP
rs751410997 25 dbSNP
rs779935953 25 dbSNP
rs764740177 28 dbSNP
rs375536209 34 dbSNP
rs200899276 35 dbSNP
rs187794245 38 dbSNP
rs77945063 40 dbSNP
rs1249687224 41 dbSNP
rs551479590 45 dbSNP
rs570263680 46 dbSNP
rs199787312 50 dbSNP
rs548847459 50 dbSNP
rs1460743753 61 dbSNP
rs917999943 70 dbSNP
rs578013020 76 dbSNP
rs1379436484 84 dbSNP
rs765606333 92 dbSNP
rs928006759 94 dbSNP
rs750850947 104 dbSNP
rs1396260223 111 dbSNP
rs555983198 123 dbSNP
rs1423874548 124 dbSNP
rs574643393 128 dbSNP
rs1383362513 129 dbSNP
rs1165206177 132 dbSNP
rs1445088594 133 dbSNP
rs138664045 137 dbSNP
rs909177332 139 dbSNP
rs941446501 146 dbSNP
rs780724691 148 dbSNP
rs1335814723 153 dbSNP
rs921420894 154 dbSNP
rs1038678527 173 dbSNP
rs1490319702 175 dbSNP
rs1290299460 176 dbSNP
rs1443645539 177 dbSNP
rs1322636038 179 dbSNP
rs1295311720 184 dbSNP
rs934267310 185 dbSNP
rs1281786237 189 dbSNP
rs1354788625 191 dbSNP
rs1233078575 192 dbSNP
rs1403843616 202 dbSNP
rs1274167046 203 dbSNP
rs1051759147 206 dbSNP
rs1196970214 215 dbSNP
rs1426916407 216 dbSNP
rs545199889 216 dbSNP
rs1426092510 218 dbSNP
rs1194469199 220 dbSNP
rs1480182321 224 dbSNP
rs999562992 237 dbSNP
rs1225280445 240 dbSNP
rs1489110900 243 dbSNP
rs1018040577 253 dbSNP
rs553475764 272 dbSNP
rs1308863603 280 dbSNP
rs903500934 285 dbSNP
rs572023522 287 dbSNP
rs1222369500 288 dbSNP
rs149329846 289 dbSNP
rs1184012390 337 dbSNP
rs893597431 339 dbSNP
rs1284654982 343 dbSNP
rs1387225335 346 dbSNP
rs1000567659 347 dbSNP
rs1010651016 350 dbSNP
rs1296222296 353 dbSNP
rs1474815542 353 dbSNP
rs1402727275 368 dbSNP
rs1463388697 368 dbSNP
rs1171573448 373 dbSNP
rs1031665630 374 dbSNP
rs1427232030 374 dbSNP
rs956993402 383 dbSNP
rs992373748 389 dbSNP
rs746674580 394 dbSNP
rs1481862006 396 dbSNP
rs1463782921 400 dbSNP
rs1025064525 402 dbSNP
rs1023499845 403 dbSNP
rs1396686463 410 dbSNP
rs564175101 412 dbSNP
rs1233383247 419 dbSNP
rs1335086613 419 dbSNP
rs1304875004 420 dbSNP
rs1393075421 429 dbSNP
rs981241771 431 dbSNP
rs969188617 450 dbSNP
rs1411167180 458 dbSNP
rs1003477354 459 dbSNP
rs1035317561 460 dbSNP
rs1331568051 462 dbSNP
rs951418579 463 dbSNP
rs1414685120 465 dbSNP
rs1157471287 472 dbSNP
rs1442097343 484 dbSNP
rs1239115390 489 dbSNP
rs1183395989 490 dbSNP
rs1459672868 494 dbSNP
rs1257915211 497 dbSNP
rs752192400 498 dbSNP
rs755684639 499 dbSNP
rs1200532686 501 dbSNP
rs777209468 506 dbSNP
rs1294352506 509 dbSNP
rs909326788 510 dbSNP
rs1354365115 511 dbSNP
rs1357755193 512 dbSNP
rs1243562161 518 dbSNP
rs1336472437 519 dbSNP
rs1396829903 531 dbSNP
rs1384271022 535 dbSNP
rs543811056 539 dbSNP
rs1250986627 543 dbSNP
rs972129905 547 dbSNP
rs909879266 552 dbSNP
rs919262123 557 dbSNP
rs962798075 560 dbSNP
rs1187746725 567 dbSNP
rs1446090889 569 dbSNP
rs1259010405 579 dbSNP
rs929842679 584 dbSNP
rs1488564190 586 dbSNP
rs1291021761 592 dbSNP
rs773227908 602 dbSNP
rs1485330505 603 dbSNP
rs760607619 607 dbSNP
rs1259429180 613 dbSNP
rs576670161 613 dbSNP
rs1401974146 614 dbSNP
rs942571441 616 dbSNP
rs1303008682 620 dbSNP
rs560274784 622 dbSNP
rs1393268127 623 dbSNP
rs878888038 633 dbSNP
rs398097595 634 dbSNP
rs60926083 634 dbSNP
rs1371035588 635 dbSNP
rs1000939835 639 dbSNP
rs112346857 642 dbSNP
rs1030585902 645 dbSNP
rs1267561858 654 dbSNP
rs1051358043 659 dbSNP
rs544026541 660 dbSNP
rs892140535 663 dbSNP
rs752291529 674 dbSNP
rs1195047214 675 dbSNP
rs1338953980 681 dbSNP
rs193207880 682 dbSNP
rs1220705489 693 dbSNP
rs376280973 697 dbSNP
rs1282757307 700 dbSNP
rs1403597787 704 dbSNP
rs185231308 705 dbSNP
rs370699254 709 dbSNP
rs1333374936 711 dbSNP
rs1052563818 717 dbSNP
rs1409811728 721 dbSNP
rs1393873104 726 dbSNP
rs770517656 731 dbSNP
rs778717055 733 dbSNP
rs1172288420 739 dbSNP
rs1170349661 750 dbSNP
rs1013764044 753 dbSNP
rs7481228 755 dbSNP
rs1196686974 761 dbSNP
rs1478949505 763 dbSNP
rs1247264439 764 dbSNP
rs1025199231 765 dbSNP
rs1200710195 766 dbSNP
rs969946801 772 dbSNP
rs1434714791 774 dbSNP
rs1010680430 778 dbSNP
rs1181344399 779 dbSNP
rs147261748 781 dbSNP
rs11309470 782 dbSNP
rs1173601588 782 dbSNP
rs1384168002 782 dbSNP
rs1404948292 782 dbSNP
rs1415735609 782 dbSNP
rs1447011063 782 dbSNP
rs1491179179 782 dbSNP
rs56800713 782 dbSNP
rs767970507 782 dbSNP
rs773141546 782 dbSNP
rs796900974 782 dbSNP
rs1425775549 787 dbSNP
rs1314030847 795 dbSNP
rs1377741032 797 dbSNP
rs1380910451 798 dbSNP
rs1157872972 799 dbSNP
rs1295258292 799 dbSNP
rs1239733733 800 dbSNP
rs1468560061 800 dbSNP
rs979588033 801 dbSNP
rs1327285616 802 dbSNP
rs879223991 803 dbSNP
rs1002409374 804 dbSNP
rs1229854180 804 dbSNP
rs796155764 808 dbSNP
rs1279436994 809 dbSNP
rs1223667717 810 dbSNP
rs1352188304 810 dbSNP
rs1273210699 811 dbSNP
rs878878093 814 dbSNP
rs1016758820 815 dbSNP
rs1282401628 816 dbSNP
rs370918342 816 dbSNP
rs1449797812 818 dbSNP
rs917920969 818 dbSNP
rs1487238933 819 dbSNP
rs929292105 826 dbSNP
rs1262143187 829 dbSNP
rs1398852131 829 dbSNP
rs1448432564 830 dbSNP
rs3740628 831 dbSNP
rs1196302217 835 dbSNP
rs188596705 838 dbSNP
rs1473910386 842 dbSNP
rs1454346341 845 dbSNP
rs1174923319 846 dbSNP
rs905037940 856 dbSNP
rs1397464153 865 dbSNP
rs1003749630 876 dbSNP
rs1288852916 881 dbSNP
rs1217797122 882 dbSNP
rs192758511 883 dbSNP
rs919228037 889 dbSNP
rs1229640785 890 dbSNP
rs1379497820 892 dbSNP
rs951409392 893 dbSNP
rs1269059642 895 dbSNP
rs1397661472 896 dbSNP
rs1362376264 904 dbSNP
rs1298663170 910 dbSNP
rs1347851727 915 dbSNP
rs1288703887 925 dbSNP
rs1166692464 936 dbSNP
rs1425748108 940 dbSNP
rs1386112384 941 dbSNP
rs1004121606 942 dbSNP
rs1185988235 943 dbSNP
rs771929509 943 dbSNP
rs1370451523 944 dbSNP
rs986695784 945 dbSNP
rs759209411 951 dbSNP
rs975481289 953 dbSNP
rs533155403 954 dbSNP
rs551419966 968 dbSNP
rs569807905 970 dbSNP
rs942521451 971 dbSNP
rs1305669749 982 dbSNP
rs1216417829 983 dbSNP
rs1271934572 983 dbSNP
rs1341773369 988 dbSNP
rs1315097155 994 dbSNP
rs1404216250 995 dbSNP
rs1238228389 1000 dbSNP
rs1365452392 1003 dbSNP
rs1295046945 1021 dbSNP
rs4988291 1023 dbSNP
rs1352578731 1025 dbSNP
rs184154067 1041 dbSNP
rs1207786409 1042 dbSNP
rs987412003 1043 dbSNP
rs73508104 1044 dbSNP
rs1468613072 1045 dbSNP
rs1171531432 1048 dbSNP
rs936401006 1049 dbSNP
rs1235802743 1051 dbSNP
rs934934874 1055 dbSNP
rs1159007515 1056 dbSNP
rs990380817 1058 dbSNP
rs1232680017 1059 dbSNP
rs1196313578 1061 dbSNP
rs1319592358 1064 dbSNP
rs1258106213 1065 dbSNP
rs1222422702 1068 dbSNP
rs144583050 1069 dbSNP
rs1303401720 1070 dbSNP
rs139467236 1077 dbSNP
rs1372266433 1078 dbSNP
rs946333458 1093 dbSNP
rs1044841576 1097 dbSNP
rs1163164438 1102 dbSNP
rs140103060 1106 dbSNP
rs1402796210 1121 dbSNP
rs749196576 1123 dbSNP
rs1465665862 1127 dbSNP
rs546437384 1127 dbSNP
rs1046623582 1129 dbSNP
rs1434277404 1133 dbSNP
rs1380032089 1136 dbSNP
rs1177201354 1143 dbSNP
rs1458798873 1145 dbSNP
rs905482326 1161 dbSNP
rs1202475136 1163 dbSNP
rs1481948524 1167 dbSNP
rs904982839 1172 dbSNP
rs1002872081 1176 dbSNP
rs1390826510 1180 dbSNP
rs373571700 1182 dbSNP
rs939107030 1184 dbSNP
rs1306782593 1193 dbSNP
rs762056496 1194 dbSNP
rs1379394425 1200 dbSNP
rs886928897 1203 dbSNP
rs1332218515 1216 dbSNP
rs1337414097 1222 dbSNP
rs1004556748 1223 dbSNP
rs752252870 1228 dbSNP
rs1304694722 1229 dbSNP
rs1016776897 1233 dbSNP
rs1360500705 1235 dbSNP
rs1335134532 1237 dbSNP
rs1442004865 1238 dbSNP
rs1215159289 1241 dbSNP
rs765401727 1245 dbSNP
rs111277924 1246 dbSNP
rs551606026 1251 dbSNP
rs762389522 1251 dbSNP
rs996763448 1258 dbSNP
rs554057626 1259 dbSNP
rs1480026249 1260 dbSNP
rs1283882931 1267 dbSNP
rs572024779 1268 dbSNP
rs1354079211 1271 dbSNP
rs955674878 1272 dbSNP
rs144982350 1275 dbSNP
rs1032278969 1282 dbSNP
rs1244285298 1306 dbSNP
rs1338965122 1307 dbSNP
rs1314911105 1312 dbSNP
rs1421357440 1313 dbSNP
rs956205370 1315 dbSNP
rs990410397 1316 dbSNP
rs914789896 1322 dbSNP
rs948950069 1330 dbSNP
rs963958117 1331 dbSNP
rs1462227414 1333 dbSNP
rs763418405 1335 dbSNP
rs1167380545 1348 dbSNP
rs1361513476 1349 dbSNP
rs980467220 1351 dbSNP
rs1456046589 1355 dbSNP
rs766920719 1357 dbSNP
rs1187639856 1361 dbSNP
rs1352923017 1378 dbSNP
rs926296417 1393 dbSNP
rs1260429320 1402 dbSNP
rs939122847 1411 dbSNP
rs550276001 1423 dbSNP
rs755489902 1426 dbSNP
rs557832622 1430 dbSNP
rs1052116984 1431 dbSNP
rs1207892861 1435 dbSNP
rs1438309151 1439 dbSNP
rs1354489253 1441 dbSNP
rs1245800452 1444 dbSNP
rs1292506740 1444 dbSNP
rs1339855838 1445 dbSNP
rs1276406751 1447 dbSNP
rs371872691 1449 dbSNP
rs779351570 1450 dbSNP
rs1323300415 1453 dbSNP
rs1393339348 1456 dbSNP
rs913687204 1456 dbSNP
rs763617085 1463 dbSNP
rs1269771436 1467 dbSNP
rs576183049 1469 dbSNP
rs1198437605 1470 dbSNP
rs117902029 1473 dbSNP
rs188435298 1474 dbSNP
rs1190987269 1476 dbSNP
rs112362886 1477 dbSNP
rs1371978612 1479 dbSNP
rs1172243859 1481 dbSNP
rs1457988762 1482 dbSNP
rs377534807 1483 dbSNP
rs397843685 1483 dbSNP
rs4988290 1483 dbSNP
rs748238740 1485 dbSNP
rs1453047442 1486 dbSNP
rs748234960 1487 dbSNP
rs1267803580 1489 dbSNP
rs899312081 1495 dbSNP
rs1302913503 1496 dbSNP
rs1341599388 1498 dbSNP
rs1378420547 1498 dbSNP
rs1384394223 1502 dbSNP
rs1294086125 1507 dbSNP
rs1325885817 1508 dbSNP
rs1220611631 1512 dbSNP
rs772463503 1513 dbSNP
rs1340676525 1514 dbSNP
rs1294150530 1526 dbSNP
rs1008745150 1528 dbSNP
rs1274715478 1529 dbSNP
rs1357535368 1531 dbSNP
rs111503828 1535 dbSNP
rs1026395624 1537 dbSNP
rs1489177782 1540 dbSNP
rs566717955 1541 dbSNP
rs956407871 1545 dbSNP
rs761145593 1547 dbSNP
rs1423823572 1549 dbSNP
rs1445545560 1551 dbSNP
rs766729090 1553 dbSNP
rs1397736494 1555 dbSNP
rs1382920531 1562 dbSNP
rs758978317 1565 dbSNP
rs1465748916 1567 dbSNP
rs890585721 1574 dbSNP
rs1170682287 1576 dbSNP
rs770058779 1580 dbSNP
rs990358001 1580 dbSNP
rs1374198318 1582 dbSNP
rs1158919162 1586 dbSNP
rs1361513312 1588 dbSNP
rs541313410 1597 dbSNP
rs1021796289 1600 dbSNP
rs1291012775 1602 dbSNP
rs766743342 1604 dbSNP
rs778540471 1605 dbSNP
rs1317246206 1608 dbSNP
rs12941 1609 dbSNP
rs533483930 1612 dbSNP
rs1217937425 1613 dbSNP
rs555734486 1617 dbSNP
rs1432855947 1620 dbSNP
rs567415428 1628 dbSNP
rs758174820 1629 dbSNP
rs142423866 1631 dbSNP
rs939771417 1633 dbSNP
rs1038198916 1635 dbSNP
rs779871299 1640 dbSNP
rs987972452 1643 dbSNP
rs1416411608 1648 dbSNP
rs913739534 1649 dbSNP
rs1458223961 1650 dbSNP
rs1245492386 1652 dbSNP
rs1437521965 1655 dbSNP
rs752241096 1659 dbSNP
rs757878331 1662 dbSNP
rs1213392350 1667 dbSNP
rs1236649159 1670 dbSNP
rs777838665 1670 dbSNP
rs981838992 1675 dbSNP
rs749565613 1680 dbSNP
rs763756453 1681 dbSNP
rs1202178428 1682 dbSNP
rs926283152 1684 dbSNP
rs1444624048 1686 dbSNP
rs1281747353 1688 dbSNP
rs751170820 1689 dbSNP
rs757005388 1691 dbSNP
rs1178818568 1692 dbSNP
rs1351888704 1695 dbSNP
rs759226468 1696 dbSNP
rs1381781635 1697 dbSNP
rs932592759 1699 dbSNP
rs1223952343 1700 dbSNP
rs1421190499 1702 dbSNP
rs1378036661 1706 dbSNP
rs1414211808 1711 dbSNP
rs1157355775 1722 dbSNP
rs1449674478 1723 dbSNP
rs1355550569 1728 dbSNP
rs563372709 1735 dbSNP
rs746919664 1736 dbSNP
rs1008191312 1737 dbSNP
rs1339327439 1740 dbSNP
rs1403939420 1742 dbSNP
rs1053528566 1743 dbSNP
rs530899398 1744 dbSNP
rs1159070089 1745 dbSNP
rs768508729 1745 dbSNP
rs780109560 1746 dbSNP
rs116021975 1747 dbSNP
rs1312603765 1759 dbSNP
rs1193512797 1760 dbSNP
rs772231527 1760 dbSNP
rs113019159 1761 dbSNP
rs535323768 1761 dbSNP
rs1261208258 1763 dbSNP
rs778173796 1764 dbSNP
rs748191206 1766 dbSNP
rs1234166959 1767 dbSNP
rs1035910509 1772 dbSNP
rs1176307187 1774 dbSNP
rs960654299 1775 dbSNP
rs1250230862 1776 dbSNP
rs372198942 1778 dbSNP
rs771216559 1779 dbSNP
rs1347904803 1781 dbSNP
rs961138149 1781 dbSNP
rs1427822980 1782 dbSNP
rs1469304962 1783 dbSNP
rs1171464761 1787 dbSNP
rs556237961 1788 dbSNP
rs1440256729 1790 dbSNP
rs1170107596 1800 dbSNP
rs1280574991 1804 dbSNP
rs1297873085 1806 dbSNP
rs1477113706 1812 dbSNP
rs180906394 1818 dbSNP
rs957909225 1823 dbSNP
rs1245370230 1824 dbSNP
rs1281235980 1826 dbSNP
rs1322710390 1827 dbSNP
rs1219244645 1831 dbSNP
rs1256210555 1834 dbSNP
rs769996586 1835 dbSNP
rs1216320474 1836 dbSNP
rs1020715264 1839 dbSNP
rs759904923 1843 dbSNP
rs932456719 1843 dbSNP
rs1203318675 1844 dbSNP
rs1218588766 1845 dbSNP
rs970550662 1846 dbSNP
rs1295100726 1853 dbSNP
rs1443333190 1854 dbSNP
rs529088918 1855 dbSNP
rs1395551539 1858 dbSNP
rs183597138 1861 dbSNP
rs1464193886 1864 dbSNP
rs912521715 1865 dbSNP
rs937682931 1867 dbSNP
rs1267283642 1871 dbSNP
rs1480395711 1872 dbSNP
rs770377200 1874 dbSNP
rs943946863 1875 dbSNP
rs189542273 1880 dbSNP
rs775925201 1881 dbSNP
rs891783605 1882 dbSNP
rs1408304566 1884 dbSNP
rs1011687549 1885 dbSNP
rs113945723 1886 dbSNP
rs1043134592 1888 dbSNP
rs1350695300 1890 dbSNP
rs376806352 1892 dbSNP
rs973519014 1896 dbSNP
rs906039708 1897 dbSNP
rs1001670246 1913 dbSNP
rs1400509432 1914 dbSNP
rs1271879595 1916 dbSNP
rs1359202253 1921 dbSNP
rs1213482722 1922 dbSNP
rs1446370552 1923 dbSNP
rs929512389 1928 dbSNP
rs59291393 1929 dbSNP
rs78069174 1933 dbSNP
rs1218529634 1934 dbSNP
rs1219886130 1948 dbSNP
rs1290008247 1951 dbSNP
rs1490303992 1953 dbSNP
rs1217073808 1954 dbSNP
rs772572062 1956 dbSNP
rs1308712388 1962 dbSNP
rs778937286 1970 dbSNP
rs1185988240 1972 dbSNP
rs1386009898 1973 dbSNP
rs1005529905 1975 dbSNP
rs57625555 1976 dbSNP
rs1465964301 1978 dbSNP
rs900619644 1984 dbSNP
rs767071024 1985 dbSNP
rs1420110935 1990 dbSNP
rs1320130495 2003 dbSNP
rs1343378989 2005 dbSNP
rs1996 2007 dbSNP
rs555440756 2008 dbSNP
rs574107030 2010 dbSNP
rs1243296174 2011 dbSNP
rs1313958716 2019 dbSNP
rs1359125461 2021 dbSNP
rs891809872 2022 dbSNP
rs1180824472 2028 dbSNP
rs1026653801 2030 dbSNP
rs1482227732 2031 dbSNP
rs1208527103 2034 dbSNP
rs1224695940 2035 dbSNP
rs541603034 2036 dbSNP
rs1445766947 2038 dbSNP
rs1215753049 2043 dbSNP
rs1337806613 2045 dbSNP
rs753788021 2048 dbSNP
rs758560015 2053 dbSNP
rs553194973 2054 dbSNP
rs1384850913 2061 dbSNP
rs182261946 2062 dbSNP
rs1435906158 2066 dbSNP
rs943993232 2073 dbSNP
rs1360239264 2078 dbSNP
rs545331054 2081 dbSNP
rs368324749 2082 dbSNP
rs758541647 2083 dbSNP
rs1003819628 2087 dbSNP
rs1333026194 2090 dbSNP
rs1033430356 2094 dbSNP
rs1186218705 2103 dbSNP
rs913250243 2108 dbSNP
rs1453415845 2110 dbSNP
rs973186164 2112 dbSNP
rs920231705 2115 dbSNP
rs760840944 2117 dbSNP
rs766830713 2130 dbSNP
rs186927657 2132 dbSNP
rs1415380618 2135 dbSNP
rs1474716871 2140 dbSNP
rs73508108 2141 dbSNP
rs1319949873 2146 dbSNP
rs1392356728 2146 dbSNP
rs1295230743 2149 dbSNP
rs1407732069 2150 dbSNP
rs1296722947 2155 dbSNP
rs944886169 2156 dbSNP
rs1162216833 2157 dbSNP
rs1456095791 2157 dbSNP
rs905985700 2165 dbSNP
rs572335407 2173 dbSNP
rs936055275 2174 dbSNP
rs1195248586 2180 dbSNP
rs561444717 2186 dbSNP
rs777927518 2186 dbSNP
rs1266437765 2188 dbSNP
rs151294029 2188 dbSNP
rs1209422790 2202 dbSNP
rs1467340212 2208 dbSNP
rs1275098913 2209 dbSNP
rs891777357 2212 dbSNP
rs1317837319 2215 dbSNP
rs1010219497 2216 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 55291.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ggccaGGCAUGUUUGAGACGUc 5'
               |:| ||  |||||||| 
Target 5' cacugCUGCACUCACUCUGCAa 3'
 		2 - 23
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000393800.2 | 3UTR | UCACUGCUGCACUCACUCUGCAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC -0.305 0.21 -0.167 0.33 9 Click to see details
LUSC -0.223 0.39 -0.400 0.3 4 Click to see details
HNSC -0.095 0.39 0.136 0.35 11 Click to see details
HNSC -0.095 0.39 0.136 0.35 11 Click to see details
HNSC -0.095 0.39 0.136 0.35 11 Click to see details
HNSC -0.095 0.39 0.136 0.35 11 Click to see details
HNSC -0.095 0.39 0.136 0.35 11 Click to see details
HNSC -0.095 0.39 0.136 0.35 11 Click to see details
HNSC -0.095 0.39 0.136 0.35 11 Click to see details
HNSC -0.095 0.39 0.136 0.35 11 Click to see details
HNSC -0.095 0.39 0.136 0.35 11 Click to see details
HNSC -0.095 0.39 0.136 0.35 11 Click to see details
86 hsa-miR-3678-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT074327 TNRC6A trinucleotide repeat containing 6A 2 10
MIRT107705 CLTA clathrin light chain A 2 2
MIRT114113 AGO1 argonaute 1, RISC catalytic component 2 2
MIRT155293 IFNAR2 interferon alpha and beta receptor subunit 2 2 4
MIRT159171 NRBP1 nuclear receptor binding protein 1 2 2
MIRT185795 ZNF678 zinc finger protein 678 2 2
MIRT282672 SYNM synemin 2 2
MIRT294386 ZNF264 zinc finger protein 264 2 2
MIRT295818 CHMP4B charged multivesicular body protein 4B 2 2
MIRT332777 CAPRIN1 cell cycle associated protein 1 2 4
MIRT334112 PPP6R3 protein phosphatase 6 regulatory subunit 3 2 2
MIRT340971 IPO5 importin 5 2 2
MIRT354679 CDV3 CDV3 homolog 2 2
MIRT366662 PLP2 proteolipid protein 2 2 2
MIRT404272 PLEKHA8 pleckstrin homology domain containing A8 2 2
MIRT447536 RNF165 ring finger protein 165 2 2
MIRT449139 UQCRB ubiquinol-cytochrome c reductase binding protein 2 2
MIRT451301 LGALS3BP galectin 3 binding protein 2 2
MIRT451488 FOPNL FGFR1OP N-terminal like 2 2
MIRT455198 GNL1 G protein nucleolar 1 (putative) 2 2
MIRT459215 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT461764 MPDU1 mannose-P-dolichol utilization defect 1 2 2
MIRT463273 ZFX zinc finger protein, X-linked 2 2
MIRT464862 UBB ubiquitin B 2 8
MIRT464950 TWIST1 twist family bHLH transcription factor 1 2 2
MIRT467378 SON SON DNA binding protein 2 4
MIRT469282 RHOA ras homolog family member A 2 2
MIRT470293 PPTC7 PTC7 protein phosphatase homolog 2 2
MIRT470639 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT477163 FABP3 fatty acid binding protein 3 2 2
MIRT477686 EFHD2 EF-hand domain family member D2 2 2
MIRT479725 CCNF cyclin F 2 2
MIRT481726 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT485673 CCDC64 BICD family like cargo adaptor 1 2 2
MIRT498280 PADI2 peptidyl arginine deiminase 2 2 2
MIRT499921 GPX8 glutathione peroxidase 8 (putative) 2 2
MIRT503616 SLC25A36 solute carrier family 25 member 36 2 4
MIRT506927 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT507348 FAM129A family with sequence similarity 129 member A 2 6
MIRT508265 DYNLL2 dynein light chain LC8-type 2 2 4
MIRT508284 YES1 YES proto-oncogene 1, Src family tyrosine kinase 2 4
MIRT509353 COPS8 COP9 signalosome subunit 8 2 2
MIRT510892 RAB1A RAB1A, member RAS oncogene family 2 4
MIRT511882 GAS1 growth arrest specific 1 2 6
MIRT511990 E2F1 E2F transcription factor 1 2 4
MIRT512239 ARPP19 cAMP regulated phosphoprotein 19 2 4
MIRT512392 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 4
MIRT514086 EPS15L1 epidermal growth factor receptor pathway substrate 15 like 1 2 6
MIRT514358 UBBP4 ubiquitin B pseudogene 4 2 6
MIRT523149 HNRNPU heterogeneous nuclear ribonucleoprotein U 2 2
MIRT525511 FSIP2 fibrous sheath interacting protein 2 2 2
MIRT526333 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT529962 ZNF71 zinc finger protein 71 2 2
MIRT530337 GABRB3 gamma-aminobutyric acid type A receptor beta3 subunit 2 2
MIRT530884 PHOX2A paired like homeobox 2a 2 2
MIRT533097 YOD1 YOD1 deubiquitinase 2 2
MIRT533250 VCAM1 vascular cell adhesion molecule 1 2 2
MIRT534786 RAB8B RAB8B, member RAS oncogene family 2 2
MIRT537917 DSTYK dual serine/threonine and tyrosine protein kinase 2 2
MIRT547799 JARID2 jumonji and AT-rich interaction domain containing 2 2 2
MIRT548714 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT555509 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT555984 NFYB nuclear transcription factor Y subunit beta 2 2
MIRT557942 FAM222B family with sequence similarity 222 member B 2 2
MIRT560830 ZNF786 zinc finger protein 786 2 2
MIRT562720 ZNF714 zinc finger protein 714 2 2
MIRT565337 TMEM104 transmembrane protein 104 2 2
MIRT614453 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT639474 SLC6A4 solute carrier family 6 member 4 2 2
MIRT644056 IQCE IQ motif containing E 2 2
MIRT651652 VWA1 von Willebrand factor A domain containing 1 2 2
MIRT651866 UNC119B unc-119 lipid binding chaperone B 2 2
MIRT653490 SLC43A2 solute carrier family 43 member 2 2 2
MIRT657039 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT657985 GAN gigaxonin 2 2
MIRT672117 ATP6V0A2 ATPase H+ transporting V0 subunit a2 2 2
MIRT683583 GSTCD glutathione S-transferase C-terminal domain containing 2 2
MIRT688689 CPS1 carbamoyl-phosphate synthase 1 2 2
MIRT695375 NSA2 NSA2, ribosome biogenesis homolog 2 2
MIRT696351 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT700614 PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 2 2
MIRT703512 FKBP15 FK506 binding protein 15 2 2
MIRT705051 C5orf15 chromosome 5 open reading frame 15 2 2
MIRT705180 BTG1 BTG anti-proliferation factor 1 2 2
MIRT709409 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT721053 DCC DCC netrin 1 receptor 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3678-3p Platinum 23939 resistant tissue
hsa-miR-3678-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3678-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-3678-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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