miRTarBase - #MIRT350659


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pre-miRNA Information
pre-miRNA hsa-mir-7515   
Genomic Coordinates chr2: 6650373 - 6650439
Description Homo sapiens miR-7515 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-7515
Sequence 46| AGAAGGGAAGAUGGUGAC |63
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1451879371 1 dbSNP
rs576086800 3 dbSNP
rs753372632 5 dbSNP
rs1337497055 7 dbSNP
rs1405449301 9 dbSNP
rs1032296398 10 dbSNP
rs960195576 12 dbSNP
rs1470711310 14 dbSNP
Putative Targets

Gene Information
Gene Symbol PDIA6   
Synonyms ERP5, P5, TXNDC7
Description protein disulfide isomerase family A member 6
Transcript NM_005742   
Expression
Putative miRNA Targets on PDIA6
3'UTR of PDIA6
(miRNA target sites are highlighted)		 
>PDIA6|NM_005742|3'UTR
   1 GAGCCACAACAGAGGCTTCAGACCATTTTCTTTTCTTGGGAGCCAGTGGATTTTTCCAGCAGTGAAGGGACATTCTCTAC
  81 ACTCAGATGACTCTACCAGTGGCCTTTTAACCAAGAAGTAGTACTTGATTGGTCATTTGAAAACACTGCAACAGTGAACT
 161 TTTGCATCTCAAGAAAACATTGAAAAATTCTATGAATTGTTGTAGCCGGTGAATTGAGTCGTATTCTGTCACATAATATT
 241 TTGAAGAAAACTTGGCTGTCGAAACATTTTTCTCTCTGACTGCTGCTTGAATGTTCTTGGAGGCTGTTTCTTATGTATGG
 321 GTTTTTTTTAATGTGATCCCTTCATTTGAATATTAATGGCTTTTTCCATTAAAGAATAAAATATTTTGGACAATGCCGAT
 401 AAATGTATGAAGTTAGTATCCACATCATAAATTCAGAGTGATGTTTAGCAGTAAATCAATATTTTGAAGTGATACACAGA
 481 TGTCTTTCCTCCCCACAAACTTTTTTAAACAAAAAACAAGACCTCTTTTCTTTAGATGGTGCCACCTATGCCCACCACAA
 561 CAGAGATTTTACATGGAAACCGGGCTCAGTGAGAACTGATTTCCTGCCCAATATTTGTCTTTGGGCTGTCTCTAGTGACT
 641 AATTATTAAGGAATCTAGCTGGTTATACAGTTCAAGGCTTTCTATGTTGTTAATGAACCTCAAAATAGCCGTTAAGACAT
 721 GAAATACAGCAGCAGGTTACCAATGCGAACAGGTAGTTCGCATTTATGTAAAACATTCAGAAAATGAAGTTTTGAATTTG
 801 TTGGAACATTCAAAGGACTTGAGAGCATTTTATTGTAACTTAAAAAAATAAATACAACTGTCACTAAAAAAAAAAAAAAA
 881 AAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' caGUGGUAGAAGGGAAGa 5'
            :| ::|  ||||||| 
Target 5' ttTAATGTGATCCCTTCa 3'
 327 - 344 144.00 -9.30
2 
miRNA  3' cagUGGUAGAAGGGAAGa 5'
             |||||:|||::||| 
Target 5' cagACCATTTTCTTTTCt 3'
 19 - 36 139.00 -17.50
3 
miRNA  3' cagUGGUAGAAGGGAAGa 5'
             ||| ||||::|||: 
Target 5' aagACC-TCTTTTCTTTa 3'
 518 - 534 114.00 -10.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30490989 24 COSMIC
COSN31554237 28 COSMIC
COSN30525354 38 COSMIC
COSN30150852 64 COSMIC
COSN25778987 93 COSMIC
COSN30612677 105 COSMIC
COSN31537417 120 COSMIC
COSN8606955 139 COSMIC
COSN26553286 165 COSMIC
COSN31605127 190 COSMIC
COSN8606954 344 COSMIC
COSN28201689 360 COSMIC
COSN26481476 397 COSMIC
COSN31550165 492 COSMIC
COSN30162470 821 COSMIC
COSN6201298 850 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1206695821 4 dbSNP
rs754632785 8 dbSNP
rs1459011709 10 dbSNP
rs1246161953 25 dbSNP
rs751303813 27 dbSNP
rs544797096 34 dbSNP
rs14337 35 dbSNP
rs899845616 36 dbSNP
rs1214435021 38 dbSNP
rs1448476471 38 dbSNP
rs565556427 40 dbSNP
rs550184829 41 dbSNP
rs1270344905 45 dbSNP
rs200948949 49 dbSNP
rs887430557 50 dbSNP
rs1198194439 52 dbSNP
rs1039753738 56 dbSNP
rs943260589 58 dbSNP
rs1159474648 62 dbSNP
rs1384776717 68 dbSNP
rs202243910 72 dbSNP
rs1305499797 75 dbSNP
rs1225590863 79 dbSNP
rs111359980 81 dbSNP
rs11545886 82 dbSNP
rs764717987 87 dbSNP
rs1324853374 92 dbSNP
rs1182933978 93 dbSNP
rs1299404110 96 dbSNP
rs554444008 99 dbSNP
rs750051227 99 dbSNP
rs1293213107 102 dbSNP
rs1240112556 114 dbSNP
rs1279910041 124 dbSNP
rs781657625 124 dbSNP
rs929035806 129 dbSNP
rs919032646 131 dbSNP
rs776004654 134 dbSNP
rs1293904064 143 dbSNP
rs1490357585 148 dbSNP
rs1208708529 162 dbSNP
rs972889889 163 dbSNP
rs1362366896 168 dbSNP
rs929164594 180 dbSNP
rs1439186626 187 dbSNP
rs867675005 188 dbSNP
rs1182148132 201 dbSNP
rs944206748 202 dbSNP
rs1438226611 206 dbSNP
rs545130737 207 dbSNP
rs574650183 208 dbSNP
rs1045476595 209 dbSNP
rs1176444991 211 dbSNP
rs1804107 219 dbSNP
rs1398802714 220 dbSNP
rs985687783 221 dbSNP
rs1370946571 223 dbSNP
rs1328444016 231 dbSNP
rs954319651 236 dbSNP
rs1237722859 239 dbSNP
rs1316963704 240 dbSNP
rs763566779 243 dbSNP
rs556342717 251 dbSNP
rs537921891 252 dbSNP
rs1429533013 254 dbSNP
rs1264283945 258 dbSNP
rs1182365102 260 dbSNP
rs1237220334 262 dbSNP
rs926232609 267 dbSNP
rs1158293897 274 dbSNP
rs1244205045 278 dbSNP
rs977952852 283 dbSNP
rs979437075 284 dbSNP
rs1461209371 289 dbSNP
rs558700720 299 dbSNP
rs1263851583 302 dbSNP
rs967557022 303 dbSNP
rs1021463049 304 dbSNP
rs1804105 307 dbSNP
rs1454821626 309 dbSNP
rs1338445730 310 dbSNP
rs3208276 310 dbSNP
rs1013398965 314 dbSNP
rs896325028 317 dbSNP
rs998255403 322 dbSNP
rs1327633650 326 dbSNP
rs1227548154 329 dbSNP
rs201184814 330 dbSNP
rs964145805 330 dbSNP
rs1205242239 336 dbSNP
rs1264081943 337 dbSNP
rs1033542840 355 dbSNP
rs1180583860 356 dbSNP
rs1264511428 358 dbSNP
rs1299462878 360 dbSNP
rs1002101456 362 dbSNP
rs1429682558 366 dbSNP
rs568869179 374 dbSNP
rs190113887 381 dbSNP
rs1381884629 384 dbSNP
rs771153946 389 dbSNP
rs16856645 393 dbSNP
rs897533824 398 dbSNP
rs764474348 405 dbSNP
rs1177433098 407 dbSNP
rs1393665407 414 dbSNP
rs75496500 415 dbSNP
rs1462179090 433 dbSNP
rs1048976610 435 dbSNP
rs993715964 436 dbSNP
rs1382749847 438 dbSNP
rs1277003935 449 dbSNP
rs1337791975 452 dbSNP
rs1224897136 459 dbSNP
rs540403004 460 dbSNP
rs1283559712 469 dbSNP
rs1161999495 470 dbSNP
rs897678579 473 dbSNP
rs768843380 475 dbSNP
rs1244335466 479 dbSNP
rs1216599597 482 dbSNP
rs949786036 488 dbSNP
rs915701646 492 dbSNP
rs912708762 499 dbSNP
rs1436206948 500 dbSNP
rs985633554 509 dbSNP
rs932897710 515 dbSNP
rs1249900009 517 dbSNP
rs1055861982 522 dbSNP
rs1420168616 527 dbSNP
rs1297511047 530 dbSNP
rs1358025549 537 dbSNP
rs1406265776 545 dbSNP
rs1303281631 547 dbSNP
rs1366426475 552 dbSNP
rs935682422 561 dbSNP
rs6748808 563 dbSNP
rs1239979727 569 dbSNP
rs977715188 570 dbSNP
rs1243445262 571 dbSNP
rs1223293796 573 dbSNP
rs536167576 581 dbSNP
rs569043087 582 dbSNP
rs1315706296 589 dbSNP
rs1409803688 597 dbSNP
rs550809230 605 dbSNP
rs1440112037 609 dbSNP
rs979362193 611 dbSNP
rs1246884080 623 dbSNP
rs769738262 639 dbSNP
rs149491730 644 dbSNP
rs753510066 645 dbSNP
rs1426513132 652 dbSNP
rs185405157 656 dbSNP
rs1348848519 662 dbSNP
rs1301717828 663 dbSNP
rs964115413 665 dbSNP
rs1018369848 669 dbSNP
rs1060002 682 dbSNP
rs1060005 684 dbSNP
rs1386233609 686 dbSNP
rs9314 688 dbSNP
rs754777878 689 dbSNP
rs1033508251 692 dbSNP
rs1289224660 692 dbSNP
rs182197560 693 dbSNP
rs951906281 697 dbSNP
rs1027573378 700 dbSNP
rs565321075 700 dbSNP
rs200126259 701 dbSNP
rs1484176515 703 dbSNP
rs192453762 710 dbSNP
rs868846415 711 dbSNP
rs1060011 718 dbSNP
rs1040067583 728 dbSNP
rs1172026596 739 dbSNP
rs767492833 741 dbSNP
rs562708971 744 dbSNP
rs544385606 746 dbSNP
rs749964258 747 dbSNP
rs1211574924 752 dbSNP
rs1348387684 753 dbSNP
rs1278471108 760 dbSNP
rs1216379685 768 dbSNP
rs1239092485 779 dbSNP
rs1317513483 797 dbSNP
rs11489 803 dbSNP
rs1255849980 807 dbSNP
rs756826731 808 dbSNP
rs773463524 809 dbSNP
rs1236861211 811 dbSNP
rs1366583072 813 dbSNP
rs559009388 821 dbSNP
rs1055566679 823 dbSNP
rs932825437 833 dbSNP
rs753318318 835 dbSNP
rs1415424877 841 dbSNP
rs904175287 849 dbSNP
rs1357896631 855 dbSNP
rs1433579708 858 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' caGUGGUAGAAGGGAAGa 5'
            :| ::|  ||||||| 
Target 5' uuUAAUGUGAUCCCUUCa 3'
 		6 - 23
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000272227.3 | 3UTR | UUUUUUUUAAUGUGAUCCCUUCAUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
116 hsa-miR-7515 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT063460 SKI SKI proto-oncogene 2 4
MIRT089615 MAT2A methionine adenosyltransferase 2A 2 10
MIRT100238 PRR3 proline rich 3 2 4
MIRT159239 NRBP1 nuclear receptor binding protein 1 2 2
MIRT183526 BTG2 BTG anti-proliferation factor 2 2 2
MIRT266866 SLC25A44 solute carrier family 25 member 44 2 2
MIRT304116 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 4
MIRT331077 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT350659 PDIA6 protein disulfide isomerase family A member 6 2 2
MIRT438442 MET MET proto-oncogene, receptor tyrosine kinase 3 1
MIRT443555 ZFP3 ZFP3 zinc finger protein 2 2
MIRT447969 MSH6 mutS homolog 6 2 2
MIRT448635 ONECUT1 one cut homeobox 1 2 2
MIRT451778 USP36 ubiquitin specific peptidase 36 2 2
MIRT452615 REPIN1 replication initiator 1 2 2
MIRT453433 GLG1 golgi glycoprotein 1 2 2
MIRT454015 ALKBH5 alkB homolog 5, RNA demethylase 2 2
MIRT454961 TPM2 tropomyosin 2 2 2
MIRT455364 KDM5C lysine demethylase 5C 2 2
MIRT455434 ID3 inhibitor of DNA binding 3, HLH protein 2 2
MIRT455456 EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2 2
MIRT455595 TAF12 TATA-box binding protein associated factor 12 2 2
MIRT455689 GLO1 glyoxalase I 2 2
MIRT455949 CYP4A22 cytochrome P450 family 4 subfamily A member 22 2 2
MIRT456135 SAMD10 sterile alpha motif domain containing 10 2 2
MIRT456821 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT457441 NOL10 nucleolar protein 10 2 2
MIRT458048 TSEN54 tRNA splicing endonuclease subunit 54 2 2
MIRT458237 NXPH3 neurexophilin 3 2 2
MIRT458671 GPR35 G protein-coupled receptor 35 2 2
MIRT458741 CES2 carboxylesterase 2 2 2
MIRT459102 CYP4A11 cytochrome P450 family 4 subfamily A member 11 2 2
MIRT459676 VPS37C VPS37C, ESCRT-I subunit 2 2
MIRT459776 IDH3A isocitrate dehydrogenase 3 (NAD(+)) alpha 2 2
MIRT461975 PACSIN1 protein kinase C and casein kinase substrate in neurons 1 2 2
MIRT462267 TPI1 triosephosphate isomerase 1 2 2
MIRT463296 ZFP91 ZFP91 zinc finger protein 2 2
MIRT463446 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT464379 URM1 ubiquitin related modifier 1 2 2
MIRT465552 TOB2 transducer of ERBB2, 2 2 2
MIRT467359 SP2 Sp2 transcription factor 2 2
MIRT467638 SLC7A5 solute carrier family 7 member 5 2 2
MIRT467795 SLC2A14 solute carrier family 2 member 14 2 2
MIRT468466 SET SET nuclear proto-oncogene 2 4
MIRT468725 SDC4 syndecan 4 2 2
MIRT468784 SCAMP5 secretory carrier membrane protein 5 2 2
MIRT469154 RNF121 ring finger protein 121 2 2
MIRT473436 MDM4 MDM4, p53 regulator 2 2
MIRT473636 MARK2 microtubule affinity regulating kinase 2 2 2
MIRT474242 LCLAT1 lysocardiolipin acyltransferase 1 2 2
MIRT474654 KLF13 Kruppel like factor 13 2 2
MIRT475384 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT475400 ICMT isoprenylcysteine carboxyl methyltransferase 2 4
MIRT476369 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT478017 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT478459 DAB2 DAB2, clathrin adaptor protein 2 2
MIRT478791 CRTC2 CREB regulated transcription coactivator 2 2 2
MIRT478952 COX15 COX15, cytochrome c oxidase assembly homolog 2 2
MIRT480412 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT481455 ARRB2 arrestin beta 2 2 2
MIRT481556 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT481740 APH1A aph-1 homolog A, gamma-secretase subunit 2 2
MIRT483592 SLC26A9 solute carrier family 26 member 9 2 2
MIRT484423 SNX19 sorting nexin 19 2 2
MIRT484727 HOXB8 homeobox B8 2 6
MIRT487419 CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 2 2
MIRT487622 C20orf96 chromosome 20 open reading frame 96 2 2
MIRT488048 PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B 2 2
MIRT488064 PABPC1L2A poly(A) binding protein cytoplasmic 1 like 2A 2 2
MIRT488587 ST7L suppression of tumorigenicity 7 like 2 2
MIRT488696 NAT9 N-acetyltransferase 9 (putative) 2 2
MIRT489175 ANKRD45 ankyrin repeat domain 45 2 4
MIRT490435 MYL9 myosin light chain 9 2 2
MIRT490452 GLUD1 glutamate dehydrogenase 1 2 2
MIRT490704 FSTL4 follistatin like 4 2 2
MIRT491038 ALPK3 alpha kinase 3 2 2
MIRT491249 HCN2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 2 2
MIRT491632 SEMA4G semaphorin 4G 2 2
MIRT492491 RAPGEF1 Rap guanine nucleotide exchange factor 1 2 2
MIRT492506 RANBP10 RAN binding protein 10 2 4
MIRT493917 FAM127B retrotransposon Gag like 8A 2 4
MIRT494012 DUSP9 dual specificity phosphatase 9 2 2
MIRT499188 RBPJL recombination signal binding protein for immunoglobulin kappa J region like 2 2
MIRT499813 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT501837 NCOA2 nuclear receptor coactivator 2 2 2
MIRT504067 KCTD12 potassium channel tetramerization domain containing 12 2 4
MIRT505313 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT511829 H2AFX H2A histone family member X 2 4
MIRT515497 GTF2F1 general transcription factor IIF subunit 1 2 2
MIRT518629 NONO non-POU domain containing octamer binding 2 2
MIRT519774 ZNF354B zinc finger protein 354B 2 8
MIRT521806 POM121C POM121 transmembrane nucleoporin C 2 2
MIRT522621 MAP7D1 MAP7 domain containing 1 2 4
MIRT532803 CLDN11 claudin 11 2 2
MIRT533783 TMEM119 transmembrane protein 119 2 2
MIRT536433 KMT2B lysine methyltransferase 2B 2 6
MIRT538700 CASP16 caspase 16, pseudogene 2 4
MIRT544603 DCAF5 DDB1 and CUL4 associated factor 5 2 2
MIRT556730 KLHL15 kelch like family member 15 2 4
MIRT560587 LCE1B late cornified envelope 1B 2 2
MIRT560617 ANKRD36 ankyrin repeat domain 36 2 2
MIRT564348 AKR1B10 aldo-keto reductase family 1 member B10 2 2
MIRT568925 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT570946 CPE carboxypeptidase E 2 2
MIRT571235 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT573805 FRMPD4 FERM and PDZ domain containing 4 2 2
MIRT574149 MARVELD1 MARVEL domain containing 1 2 2
MIRT575772 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b 2 2
MIRT576154 Hmox1 heme oxygenase 1 2 2
MIRT611312 CA8 carbonic anhydrase 8 2 4
MIRT615891 MT1A metallothionein 1A 2 2
MIRT669589 AK2 adenylate kinase 2 2 2
MIRT687186 PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha 2 2
MIRT692711 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT701346 NR4A3 nuclear receptor subfamily 4 group A member 3 2 2
MIRT701997 MIER3 MIER family member 3 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-7 Berbamine derivative(BBMD3) NULL NULL Illumina HiSeq2000 brain 24732116 2014 down-regulated
miR-7 Curcumin NULL 969516 Microarray BxPC-3 human pancreatic carcinoma cell line 18347134 2008 down-regulated
miR-7 Enoxacin approved 3229 Quantitative real-time PCR HCT-116 and RKO colon cancer cell lines 21368194 2011 up-regulated
miR-7 5-Fluorouracil approved 3385 Microarray MCF-7 breast cancer cells 21506117 2011 down-regulated
miR-7 Aidi injection NULL NULL Microarray human breast cancer cells 21563499 2011 up-regulated
miR-7 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-7 Marine fungal metabolite 1386A NULL NULL Microarray MCF-7 breast cancer cells. 22159329 2012 up-regulated
miR-7 Interleukin 13 (IL-13) NULL NULL Quantitative real-time PCR bronchial epithelial cells 22453679 2012 down-regulated
miR-7 1,2,6-Tri-O-galloyl-beta-D-glucopyranose NULL NULL Microarray HepG2 hepatocarcinoma cells. 22506400 2011 down-regulated
miR-7 Goserelin approved 47725 Microarray prostate 22674191 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-7515 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-7515 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-7515 Tamoxifen+Fulvestrant resistant cell line (LCC9)
hsa-miR-7515 Cisplatin 5460033 NSC119875 approved resistant cell line (CIS)

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