miRTarBase - #MIRT350957


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pre-miRNA Information
pre-miRNA hsa-mir-4301   
Genomic Coordinates chr11: 113450023 - 113450088
Description Homo sapiens miR-4301 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4301
Sequence 11| UCCCACUACUUCACUUGUGA |30
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs184176277 2 dbSNP
rs1191324913 13 dbSNP
rs1369198005 15 dbSNP
rs1036973189 16 dbSNP
rs944900541 18 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol BACH1   
Synonyms BACH-1, BTBD24
Description BTB domain and CNC homolog 1
Transcript NM_001186   
Other Transcripts NM_206866   
Expression
Putative miRNA Targets on BACH1
3'UTR of BACH1
(miRNA target sites are highlighted)		 
>BACH1|NM_001186|3'UTR
   1 ACTTGCATTCACTTCCTTCAAACCATCTAATTTTCTCCTGAAGTTTTGGCAGCGTCTTGAAAGCCTAATATGACCATCTG
  81 TTGCTCAACAATACTGTTTTTTTCCTTTAGTAGTTTACCATAAGGGAATTTCCTTTAAGTCAACCATGATTTCTCCTTGA
 161 TTTCTACAAGAGACAAAGAAATGATTTTGCCTCCTGGATATCAGAAAAATCCATGTGAAAATGTAGTAAACCTTTAAAAC
 241 TCATGTTTTAAAGAATAATAACTCTAGTAATAACTCTTCCTGCTATTCAGAATAAGTAGGAGAATGAAAACTGCAGCATA
 321 TCAGACAGCAATTTAACAGCTTGAAACATCTACAGATAGTTCCTACTAAAAGAAGTGGCCTGCAGAAGTTTAATAATTTG
 401 ACTTTTTTCTAATATTTTAGTTTGAAAGAAAATTTCTTCCCAAGCAATGCTAATAGAGTTCTATTCTTAGAAGCAGGGTG
 481 TCAGCTACTGGGAATATTTTTGTAGAGCTGCATTGTGAAAAAAAGATGGTCTTACCTGAATCTTAGGGCTTTGTTCTTCG
 561 GCTCCTAAAATCAGGCTTTAAGCTACATTGGGAAGATTTAGTAAATAGGCAAGTGGTTGGCCTAAGACGGGGGCTGCTTC
 641 TCCTCTTCAGTATGGACTCTAGAAAGTCTGGCTACATGAATAGATTTAAGTGTCACTTTCCCTCCCTGCCCCCCGCTTCA
 721 GTCTCTACCATATCTGGTCCCATCATGGACTTCCTATTTCCTGGCATTTTTGTCCCTTTGGAAGAAGAAATAGGACTCAG
 801 AATACAGTGGCATGAGTGATTACACTGGCAGCATTATCTCAGGCTCCCTAGAATCTGGAGAGCTTACCAACATGTAAAGC
 881 TGTTCATTTTTCCACCGTGGGTCACCAATGCCAGAAAACCAGACATCACGGGGAAAGAATGTTGCTTACTTTTTACCAGG
 961 AGTGCAGTTCATTTTTTTCACCCTGTTTTTGAAGTCGTATTATTCACTTGTAAAAATGATTGTAACAGATAAAAAATGTA
1041 TCTGCAGCAACTCTGCAGGTTTGTGAAATAGGATGAAACTCAATCTTTTTCTATTGTGGGTTTGCATTTGAAAAGCAGGT
1121 TGAATCCTTGCTCTCTTCTCCAAATTTGGTGTGGTATAAAGACACACAAATCATTTTAACTTGGACATTTAAAGATCAGT
1201 CTTAGTGTTTGTTCAGTCCTGTTACAAAATAGATAACTGAGCACCTATCGCATAACATTTTGCGGTGGCTTTTAGCCATG
1281 CTGGGGTTAGATGTGTTTGAGAGTCAAATGAAAGCTATGGATCTTCTCAGCAATTAAAAAAAATGCATATATTCACATTC
1361 ACAGAAACATTGGCAGAACCCAGTTTTAATGGTACAGAGGAGTAGTTTATAGTGTTGATTTCACCAAAATCAGAGGGCTG
1441 AAAGAGACACTTCTATAGACTGCATCCTGAGCCTAGTGCAGGGCTTGTCTAGCTAATGTGGGCAGCCACCACCCACTGTG
1521 TATGAACAAGTCTGAAGCAAGTTGGCCTTGCCCTTGAGAGTATATGGGGACCAGTCTTCATGTCTTGGAGTAATTTGTCA
1601 AATGTTACCCTTTTTGATCAGGGTGTAGGGGGAGGATATTGCTAGTATATTTTCAGTGGTTTGTATGTTCTCTCTGTCAC
1681 TGACTTATTTGTAAGAGAAAATTAGTTGGACTTGTTTATTTTCTAGTAGCTTTTATAAGTACACTCAAGAATTTGTCAGG
1761 GAGAATAATTCTGATAGTGCATCCCATACTGCAAAAGAATTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGT
1841 GTATGTATACATATATATCTCTCCATATAGGTATTTCTTTGATACTTGTAATTTTAAATTTCAGCTTCACGATATAAAAT
1921 AATATAAGAACTTCTGGTTTACAAAATGTAAAATCTTAAGCCAATGGAACCCTTGATTTCCTACCTCAGTGTACACCCAA
2001 CTATTGGTTGTATCAGTTTGTGTATGTGCAAATGTCAAATAATCTTTTGCTTTAATTGCTACTGTACTTGCTTTGAAAGA
2081 TTACCTACTATTTTATGATAAAATGTAGTTGTCTCCAGAGCTTAAATATAATTTGTAAAGCACTTGGTTTAAATTTCTCT
2161 CTACCTATAAACAGTTTAGCATTAAGGGTTTCTATTAATGACACAGAATTATTGGCCAAGTGTAATTTCTTAAAATTTAG
2241 CATTACTTTAAATAGCCAGCATGTAATACAAGTAACTACACTACCTCATATCTACATGATTTTCAAGTTGTAATGCAGAT
2321 GGACAGATAAAAAAGATTTTACGTTTGTCTTTTGGCCATAAGTGGGAAAGTTTTCTGTATATTGCATAGCATTACACATT
2401 TATGCCTATTTTAACATTAACTTCTAAAGAAGTTTTTTCTAAGAAAATGTTTCAAGGCAATATTTTTTTTGAGGCTGCCG
2481 AAGACAAATGACAGGATTATGAGTATACAGTGTATGCCTTTTCCTTCATGCAGAATTTTGAAATGTTTTCAGTTTGTATA
2561 TTGCATATTCACATGATCATTGTTCACTATTTTATGAACTGGCCTTCTCAATGTTTGATGATTTTTTAAAAGCTGTTATG
2641 TTGAATTCAGTAAAATAACATTACCTTATTTTTTTTCTTATTCAAATTCTGGAACTATAGCAAATAATTCGTTAAATTGT
2721 CATATTCAAAACAAATGTGGATACAGTCTTGGTTCTCCATCTGTAATTTTTTTTAACAGTTTGCTATAGCTTACTGCTTA
2801 ACTAATTTTAAATAAGGAAATAAGTATGTTAGATGCAGTAGACGATACAGGTTGCATGTGGACACTCAGTCACATTAACA
2881 ACTTGGGAAAAAAATGGCAATGTTACGGTGAATTCTCAGGTGAACTTTTTTCAGTTATAAAACATCTATTTTGAATCTGT
2961 AAATATTTTAAATGTTTTATTAAGGCATGTAATAAACTATTCTTTGAAACTTGTTGGGTAGAATGAAAATTAAAGCCATA
3041 ATGGTAGAAGATGGCATACTGATTATAAAAGAAGCAGAAAAACATTGATTTTTTTATATCTTTCATAATATAATTTTCTA
3121 ACAATGCAATAAAACCACTAAACTTTTGTGTCCATATTTTACTGAGACCATGTTTCATTAAAAGCATAGTTTCATAGTAT
3201 TTAATTTACATTTCTCCCTAATGTTCTTACCCAAATGTACCTGAACTAAAAAATGTTAGATGTTGGTGATAAGTTGACAG
3281 TTAAATAAAATTCTCTAAAATTGCTTCTAATTGAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agUGUUCAC--UUCAUCACCCu 5'
            ::||| |  || |||| || 
Target 5' ttGTAAGAGAAAATTAGTTGGa 3'
 1689 - 1710 124.00 -8.70
2 
miRNA  3' agUGUUCACUUCAUCACCCu 5'
            |: || |: |||| ||| 
Target 5' tgATCAG-GGTGTAGGGGGa 3'
 1615 - 1633 121.00 -14.00
3 
miRNA  3' agUGU-UCAC--UUCAUCACCCu 5'
            :|| :|||  |: || |||| 
Target 5' aaGCAGGGTGTCAGCTACTGGGa 3'
 471 - 493 120.00 -11.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20137589 6 COSMIC
COSN31525927 22 COSMIC
COSN30454416 25 COSMIC
COSN30511908 27 COSMIC
COSN30114406 31 COSMIC
COSN31492799 36 COSMIC
COSN30137380 68 COSMIC
COSN30527414 72 COSMIC
COSN30132844 81 COSMIC
COSN30101444 85 COSMIC
COSN30527386 88 COSMIC
COSN30527394 110 COSMIC
COSN31605605 113 COSMIC
COSN32058739 133 COSMIC
COSN31551895 201 COSMIC
COSN20093855 379 COSMIC
COSN21317672 516 COSMIC
COSN29430483 563 COSMIC
COSN23750709 718 COSMIC
COSN8565244 754 COSMIC
COSN23629694 1012 COSMIC
COSN5984562 1139 COSMIC
COSN31533779 1440 COSMIC
COSN31572357 1468 COSMIC
COSN30175596 1507 COSMIC
COSN26639206 1519 COSMIC
COSN29468139 1554 COSMIC
COSN31484201 1580 COSMIC
COSN19662886 1589 COSMIC
COSN31546161 1633 COSMIC
COSN25902338 1691 COSMIC
COSN7143246 1828 COSMIC
COSN7143247 1834 COSMIC
COSN20116801 1836 COSMIC
COSN31488049 1838 COSMIC
COSN24899545 2076 COSMIC
COSN18843254 2158 COSMIC
COSN30164509 2162 COSMIC
COSN10025188 2173 COSMIC
COSN31591189 2256 COSMIC
COSN31592999 2286 COSMIC
COSN26643897 2325 COSMIC
COSN28201400 2428 COSMIC
COSN26142503 2827 COSMIC
COSN31547390 2830 COSMIC
COSN29439050 2841 COSMIC
COSN15671066 2903 COSMIC
COSN30159250 2907 COSMIC
COSN30227333 2940 COSMIC
COSN31569630 2991 COSMIC
COSN26549922 3036 COSMIC
COSN31529464 3069 COSMIC
COSN8611632 3099 COSMIC
COSN31548547 3198 COSMIC
COSN20093856 3245 COSMIC
rs372883 2584 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1039451647 2 dbSNP
rs753377049 7 dbSNP
rs1434877838 16 dbSNP
rs756664051 17 dbSNP
rs754543904 21 dbSNP
rs750036850 33 dbSNP
rs1490060637 37 dbSNP
rs1160924503 39 dbSNP
rs758068493 42 dbSNP
rs539853991 43 dbSNP
rs748500043 48 dbSNP
rs1429345754 51 dbSNP
rs371371948 52 dbSNP
rs200402827 55 dbSNP
rs888040846 60 dbSNP
rs1247084455 70 dbSNP
rs1237378951 71 dbSNP
rs1314092215 72 dbSNP
rs1284175326 73 dbSNP
rs1222964532 74 dbSNP
rs1055170673 76 dbSNP
rs1480221154 77 dbSNP
rs766663645 83 dbSNP
rs140520244 85 dbSNP
rs1385607398 88 dbSNP
rs1472864409 89 dbSNP
rs1010739740 97 dbSNP
rs1056826 106 dbSNP
rs528806832 110 dbSNP
rs1378992141 114 dbSNP
rs1451375811 114 dbSNP
rs1164331942 117 dbSNP
rs960692903 121 dbSNP
rs425989 122 dbSNP
rs2832285 127 dbSNP
rs1195237677 135 dbSNP
rs747808149 153 dbSNP
rs1429582149 157 dbSNP
rs1324378366 161 dbSNP
rs771782484 164 dbSNP
rs565373808 167 dbSNP
rs531025787 169 dbSNP
rs1484478510 179 dbSNP
rs1023662143 181 dbSNP
rs76618578 187 dbSNP
rs979291257 192 dbSNP
rs1280119723 198 dbSNP
rs554708928 199 dbSNP
rs925073542 205 dbSNP
rs1414668199 217 dbSNP
rs116544520 231 dbSNP
rs1294840883 242 dbSNP
rs1380305429 245 dbSNP
rs1408075602 254 dbSNP
rs1353579510 257 dbSNP
rs149979501 261 dbSNP
rs1172104916 265 dbSNP
rs1229525996 266 dbSNP
rs985034620 267 dbSNP
rs111703019 269 dbSNP
rs1372999201 271 dbSNP
rs1191757134 279 dbSNP
rs988460624 286 dbSNP
rs1244186430 290 dbSNP
rs1290234153 294 dbSNP
rs1306529349 311 dbSNP
rs1202823547 312 dbSNP
rs908071974 316 dbSNP
rs1483359183 319 dbSNP
rs912253593 327 dbSNP
rs2070401 332 dbSNP
rs1255506846 333 dbSNP
rs1473848436 336 dbSNP
rs1163903738 338 dbSNP
rs145211547 347 dbSNP
rs183046460 348 dbSNP
rs1315422451 353 dbSNP
rs1408401291 356 dbSNP
rs771314498 362 dbSNP
rs921031567 366 dbSNP
rs939064148 369 dbSNP
rs1410039338 375 dbSNP
rs1170914746 379 dbSNP
rs558414785 391 dbSNP
rs931020489 401 dbSNP
rs1049239927 403 dbSNP
rs1459855951 403 dbSNP
rs1371492042 405 dbSNP
rs1163263390 409 dbSNP
rs1443231606 412 dbSNP
rs887936737 419 dbSNP
rs1182848623 420 dbSNP
rs1437290203 423 dbSNP
rs1434659515 435 dbSNP
rs1005175669 437 dbSNP
rs141400608 440 dbSNP
rs1342780349 444 dbSNP
rs145172120 448 dbSNP
rs568743593 453 dbSNP
rs751530924 457 dbSNP
rs896520851 461 dbSNP
rs1244962713 463 dbSNP
rs1357102066 466 dbSNP
rs1280898480 479 dbSNP
rs1442554544 486 dbSNP
rs1334828393 508 dbSNP
rs1013553277 514 dbSNP
rs1406251724 518 dbSNP
rs1366671988 523 dbSNP
rs1225679190 524 dbSNP
rs1423096613 524 dbSNP
rs777228825 533 dbSNP
rs1159530844 544 dbSNP
rs902414776 551 dbSNP
rs62211403 557 dbSNP
rs372740743 560 dbSNP
rs1001348667 561 dbSNP
rs1490549626 563 dbSNP
rs1269519816 568 dbSNP
rs1032215258 571 dbSNP
rs1221713293 583 dbSNP
rs1489790397 587 dbSNP
rs1276496424 593 dbSNP
rs75761308 602 dbSNP
rs1349424777 603 dbSNP
rs1188388432 608 dbSNP
rs775788114 610 dbSNP
rs186728760 612 dbSNP
rs996660571 613 dbSNP
rs565019060 623 dbSNP
rs1319311388 628 dbSNP
rs574568273 629 dbSNP
rs73195611 632 dbSNP
rs573467161 634 dbSNP
rs1434563549 637 dbSNP
rs1172133191 640 dbSNP
rs887766076 645 dbSNP
rs975080487 661 dbSNP
rs1197393940 662 dbSNP
rs745719284 663 dbSNP
rs931114609 666 dbSNP
rs1243782437 676 dbSNP
rs1006504398 680 dbSNP
rs1446271041 684 dbSNP
rs1281659116 688 dbSNP
rs1323836188 703 dbSNP
rs1282043110 709 dbSNP
rs764468614 710 dbSNP
rs1364625629 713 dbSNP
rs1015205123 714 dbSNP
rs1344025760 715 dbSNP
rs750161428 716 dbSNP
rs981641681 720 dbSNP
rs1299437517 722 dbSNP
rs1036229776 727 dbSNP
rs1233341346 731 dbSNP
rs909406897 733 dbSNP
rs1470399255 738 dbSNP
rs374991512 746 dbSNP
rs1272830121 755 dbSNP
rs1174285798 764 dbSNP
rs118026035 766 dbSNP
rs566120745 768 dbSNP
rs1187078415 776 dbSNP
rs748837390 799 dbSNP
rs1283673542 808 dbSNP
rs1463646780 817 dbSNP
rs1245909782 822 dbSNP
rs896762222 830 dbSNP
rs1262133619 847 dbSNP
rs913167091 848 dbSNP
rs1248926051 849 dbSNP
rs1201211278 871 dbSNP
rs916270736 877 dbSNP
rs1274290911 896 dbSNP
rs1013756077 897 dbSNP
rs1214554963 898 dbSNP
rs1045077345 902 dbSNP
rs565473880 905 dbSNP
rs979037888 909 dbSNP
rs753833826 912 dbSNP
rs1382236178 916 dbSNP
rs905188775 919 dbSNP
rs1406405196 924 dbSNP
rs1444459663 925 dbSNP
rs935202874 929 dbSNP
rs575700856 930 dbSNP
rs1321931114 931 dbSNP
rs1388253852 936 dbSNP
rs1388979519 937 dbSNP
rs191170196 938 dbSNP
rs1032826276 940 dbSNP
rs1242135516 943 dbSNP
rs1179792897 945 dbSNP
rs901663234 945 dbSNP
rs754383387 949 dbSNP
rs1340578907 950 dbSNP
rs1050484080 959 dbSNP
rs1332552120 959 dbSNP
rs561332310 961 dbSNP
rs1359259240 962 dbSNP
rs1233693047 983 dbSNP
rs767738697 996 dbSNP
rs1006242100 997 dbSNP
rs1297613849 998 dbSNP
rs533740219 1006 dbSNP
rs796403806 1019 dbSNP
rs1440124993 1027 dbSNP
rs1368615354 1028 dbSNP
rs1304948593 1031 dbSNP
rs1326958188 1031 dbSNP
rs1230363720 1035 dbSNP
rs1268800283 1037 dbSNP
rs1420464690 1039 dbSNP
rs546991910 1040 dbSNP
rs1408275785 1048 dbSNP
rs1176070101 1049 dbSNP
rs1009420859 1051 dbSNP
rs1019417447 1060 dbSNP
rs73897766 1073 dbSNP
rs1490335982 1077 dbSNP
rs1003535211 1078 dbSNP
rs752883952 1078 dbSNP
rs1035897732 1081 dbSNP
rs1306628437 1082 dbSNP
rs1222136079 1083 dbSNP
rs959108159 1084 dbSNP
rs1452605284 1088 dbSNP
rs1347506524 1091 dbSNP
rs991593763 1094 dbSNP
rs1405434179 1095 dbSNP
rs1364923110 1110 dbSNP
rs975321740 1121 dbSNP
rs1181530630 1132 dbSNP
rs8133805 1158 dbSNP
rs952466174 1159 dbSNP
rs1455168098 1160 dbSNP
rs1473842931 1182 dbSNP
rs1345405474 1187 dbSNP
rs558290148 1193 dbSNP
rs867904987 1207 dbSNP
rs979067509 1227 dbSNP
rs923604572 1230 dbSNP
rs552232753 1232 dbSNP
rs1412006241 1236 dbSNP
rs1199552249 1245 dbSNP
rs983916137 1248 dbSNP
rs569144228 1250 dbSNP
rs374218313 1251 dbSNP
rs1486434910 1252 dbSNP
rs1392430945 1253 dbSNP
rs1260327888 1255 dbSNP
rs1207111051 1258 dbSNP
rs972212980 1264 dbSNP
rs537617555 1265 dbSNP
rs949676534 1267 dbSNP
rs1222990450 1270 dbSNP
rs1330393453 1281 dbSNP
rs116050947 1287 dbSNP
rs1383704385 1294 dbSNP
rs905218975 1295 dbSNP
rs936678962 1299 dbSNP
rs1348581134 1306 dbSNP
rs1411544797 1309 dbSNP
rs1465478163 1320 dbSNP
rs1287902773 1333 dbSNP
rs1176446886 1336 dbSNP
rs1407851901 1336 dbSNP
rs78223123 1336 dbSNP
rs140665065 1337 dbSNP
rs1376421156 1346 dbSNP
rs1009623737 1347 dbSNP
rs1019494366 1348 dbSNP
rs1429457710 1350 dbSNP
rs1261407891 1357 dbSNP
rs1187105056 1358 dbSNP
rs1334173494 1366 dbSNP
rs758027475 1375 dbSNP
rs1264008643 1380 dbSNP
rs996792334 1385 dbSNP
rs1242678523 1393 dbSNP
rs1028646383 1396 dbSNP
rs1343043683 1397 dbSNP
rs551439979 1397 dbSNP
rs1229589116 1398 dbSNP
rs553343829 1412 dbSNP
rs1308037627 1413 dbSNP
rs777445695 1420 dbSNP
rs952630688 1423 dbSNP
rs370358519 1431 dbSNP
rs1307812099 1434 dbSNP
rs1015222110 1437 dbSNP
rs1337058012 1444 dbSNP
rs576811291 1451 dbSNP
rs1399493928 1456 dbSNP
rs747298083 1459 dbSNP
rs1250001650 1469 dbSNP
rs1373017338 1476 dbSNP
rs1167042483 1491 dbSNP
rs771351821 1493 dbSNP
rs1183465728 1496 dbSNP
rs539422529 1498 dbSNP
rs558943125 1503 dbSNP
rs894697101 1504 dbSNP
rs1013046486 1507 dbSNP
rs918108273 1515 dbSNP
rs1252700849 1526 dbSNP
rs1196459475 1533 dbSNP
rs182310641 1546 dbSNP
rs1422805675 1551 dbSNP
rs199882806 1554 dbSNP
rs1369888729 1557 dbSNP
rs1458053280 1561 dbSNP
rs1361374605 1563 dbSNP
rs1167764823 1571 dbSNP
rs1000560643 1575 dbSNP
rs762429295 1576 dbSNP
rs1030693616 1580 dbSNP
rs926884106 1610 dbSNP
rs1330238197 1616 dbSNP
rs936897604 1622 dbSNP
rs186536778 1628 dbSNP
rs1370474668 1639 dbSNP
rs975752829 1642 dbSNP
rs1426912184 1660 dbSNP
rs892459822 1667 dbSNP
rs1354738552 1669 dbSNP
rs574967596 1671 dbSNP
rs923196121 1674 dbSNP
rs953244233 1688 dbSNP
rs1182601408 1689 dbSNP
rs945485155 1696 dbSNP
rs1314908973 1698 dbSNP
rs1341317302 1712 dbSNP
rs373169901 1713 dbSNP
rs1202991363 1717 dbSNP
rs540769034 1718 dbSNP
rs901037325 1730 dbSNP
rs560534082 1736 dbSNP
rs1028134027 1737 dbSNP
rs1353753174 1741 dbSNP
rs888365516 1742 dbSNP
rs909044479 1754 dbSNP
rs1206313022 1758 dbSNP
rs1005434620 1763 dbSNP
rs942128165 1770 dbSNP
rs1323238960 1772 dbSNP
rs1404007965 1773 dbSNP
rs1036435669 1782 dbSNP
rs1015713554 1789 dbSNP
rs919325523 1795 dbSNP
rs532354200 1798 dbSNP
rs1201720078 1799 dbSNP
rs1056828 1801 dbSNP
rs1269541436 1801 dbSNP
rs10595449 1802 dbSNP
rs1178609305 1802 dbSNP
rs1224832681 1802 dbSNP
rs1319411865 1802 dbSNP
rs1362187129 1802 dbSNP
rs1386729188 1802 dbSNP
rs141642990 1802 dbSNP
rs1456873119 1802 dbSNP
rs1470379098 1802 dbSNP
rs72415240 1802 dbSNP
rs72435520 1802 dbSNP
rs748985747 1802 dbSNP
rs879245646 1802 dbSNP
rs1424036066 1803 dbSNP
rs1425785112 1810 dbSNP
rs1187480964 1811 dbSNP
rs1171970295 1815 dbSNP
rs1387921775 1818 dbSNP
rs894722167 1818 dbSNP
rs1193674311 1824 dbSNP
rs1464111016 1824 dbSNP
rs1245873830 1826 dbSNP
rs1451171359 1830 dbSNP
rs866139044 1830 dbSNP
rs1168958186 1832 dbSNP
rs867846259 1832 dbSNP
rs1024018862 1833 dbSNP
rs1271065473 1834 dbSNP
rs1358551510 1834 dbSNP
rs57296177 1835 dbSNP
rs1358709005 1836 dbSNP
rs1491070374 1836 dbSNP
rs969753484 1836 dbSNP
rs1043237656 1838 dbSNP
rs868863159 1838 dbSNP
rs926775732 1840 dbSNP
rs143788431 1843 dbSNP
rs1168932345 1844 dbSNP
rs1448713484 1855 dbSNP
rs1000596380 1860 dbSNP
rs1031189458 1864 dbSNP
rs1434450967 1865 dbSNP
rs1295764986 1881 dbSNP
rs1400877891 1887 dbSNP
rs1367586650 1895 dbSNP
rs989747273 1897 dbSNP
rs1229673280 1898 dbSNP
rs1340538637 1904 dbSNP
rs956456433 1911 dbSNP
rs913930553 1912 dbSNP
rs1378760636 1914 dbSNP
rs1301098303 1919 dbSNP
rs570493255 1926 dbSNP
rs1029959325 1939 dbSNP
rs945348008 1945 dbSNP
rs953315546 1956 dbSNP
rs192587100 1965 dbSNP
rs909075793 1966 dbSNP
rs754385696 1984 dbSNP
rs368322 1998 dbSNP
rs567955844 2004 dbSNP
rs1483323447 2008 dbSNP
rs932714600 2010 dbSNP
rs1412634679 2012 dbSNP
rs1179592809 2014 dbSNP
rs1207548926 2014 dbSNP
rs527383058 2014 dbSNP
rs1470917852 2015 dbSNP
rs1245856859 2016 dbSNP
rs1253131213 2025 dbSNP
rs148004426 2027 dbSNP
rs569828511 2035 dbSNP
rs570535505 2046 dbSNP
rs1188994823 2055 dbSNP
rs919342650 2058 dbSNP
rs1321288406 2067 dbSNP
rs938740626 2068 dbSNP
rs1057450937 2069 dbSNP
rs556775391 2071 dbSNP
rs371506082 2078 dbSNP
rs1409090070 2083 dbSNP
rs1378134196 2085 dbSNP
rs1304666790 2087 dbSNP
rs575135387 2089 dbSNP
rs775698125 2093 dbSNP
rs1162311599 2096 dbSNP
rs1043269819 2103 dbSNP
rs1412004885 2105 dbSNP
rs763172879 2106 dbSNP
rs374563676 2107 dbSNP
rs1192129298 2118 dbSNP
rs1488380928 2128 dbSNP
rs1263880171 2131 dbSNP
rs1218153514 2133 dbSNP
rs1330118867 2143 dbSNP
rs1391142928 2148 dbSNP
rs1226660154 2152 dbSNP
rs768966846 2162 dbSNP
rs934845239 2164 dbSNP
rs1436038301 2166 dbSNP
rs1293313771 2170 dbSNP
rs1366709361 2173 dbSNP
rs1053259800 2178 dbSNP
rs1432415927 2180 dbSNP
rs892215513 2182 dbSNP
rs1221283900 2195 dbSNP
rs1455242963 2201 dbSNP
rs1432080673 2202 dbSNP
rs1177483849 2205 dbSNP
rs1302665836 2205 dbSNP
rs1013891855 2213 dbSNP
rs539028745 2214 dbSNP
rs183066476 2217 dbSNP
rs1465464391 2221 dbSNP
rs969786218 2225 dbSNP
rs1247702902 2233 dbSNP
rs1227297834 2235 dbSNP
rs188406303 2240 dbSNP
rs1257671535 2242 dbSNP
rs1233825920 2243 dbSNP
rs549572982 2249 dbSNP
rs538569677 2266 dbSNP
rs543283944 2289 dbSNP
rs1437026424 2303 dbSNP
rs1245923571 2314 dbSNP
rs958215153 2317 dbSNP
rs367811278 2321 dbSNP
rs536658555 2329 dbSNP
rs1319556719 2332 dbSNP
rs764422320 2336 dbSNP
rs760336315 2340 dbSNP
rs141698952 2343 dbSNP
rs575131393 2344 dbSNP
rs1465917294 2347 dbSNP
rs1268034629 2348 dbSNP
rs976752813 2350 dbSNP
rs922564232 2355 dbSNP
rs1172972458 2357 dbSNP
rs932764134 2359 dbSNP
rs1450553872 2364 dbSNP
rs1026144299 2373 dbSNP
rs1056829 2376 dbSNP
rs1056830 2380 dbSNP
rs909735126 2382 dbSNP
rs1462844585 2384 dbSNP
rs1256905983 2387 dbSNP
rs1199947132 2390 dbSNP
rs941215950 2397 dbSNP
rs1036799555 2406 dbSNP
rs193192784 2409 dbSNP
rs1457979408 2414 dbSNP
rs1014090850 2417 dbSNP
rs948740120 2429 dbSNP
rs1296623514 2433 dbSNP
rs978706203 2433 dbSNP
rs1164420592 2434 dbSNP
rs1312738381 2437 dbSNP
rs553943646 2442 dbSNP
rs542534298 2447 dbSNP
rs530795242 2448 dbSNP
rs1430784025 2449 dbSNP
rs1370289108 2458 dbSNP
rs397867648 2463 dbSNP
rs5843379 2463 dbSNP
rs201276074 2471 dbSNP
rs545858051 2480 dbSNP
rs562938450 2481 dbSNP
rs1051504476 2493 dbSNP
rs1285912467 2494 dbSNP
rs1330529579 2506 dbSNP
rs1223837554 2507 dbSNP
rs892851243 2510 dbSNP
rs1483357659 2512 dbSNP
rs552567507 2513 dbSNP
rs1273560919 2515 dbSNP
rs571053589 2517 dbSNP
rs1011093312 2519 dbSNP
rs1319533578 2528 dbSNP
rs1223527904 2530 dbSNP
rs753647920 2531 dbSNP
rs150503689 2536 dbSNP
rs1482690650 2537 dbSNP
rs1284492554 2551 dbSNP
rs1007239173 2553 dbSNP
rs531493446 2561 dbSNP
rs1338239463 2574 dbSNP
rs1289706468 2578 dbSNP
rs966960920 2580 dbSNP
rs372883 2584 dbSNP
rs1181320568 2585 dbSNP
rs1407498401 2590 dbSNP
rs1391723029 2602 dbSNP
rs1162932755 2604 dbSNP
rs1029690838 2608 dbSNP
rs1365567326 2622 dbSNP
rs899120584 2623 dbSNP
rs1411956312 2640 dbSNP
rs1179742082 2646 dbSNP
rs561652343 2650 dbSNP
rs1453150906 2654 dbSNP
rs954057628 2660 dbSNP
rs985836291 2661 dbSNP
rs73342485 2665 dbSNP
rs75903526 2670 dbSNP
rs1428394608 2681 dbSNP
rs972545712 2684 dbSNP
rs918409291 2686 dbSNP
rs138680753 2689 dbSNP
rs1310448272 2695 dbSNP
rs1287081286 2698 dbSNP
rs116143045 2701 dbSNP
rs1442368366 2706 dbSNP
rs1332091047 2710 dbSNP
rs1323344639 2711 dbSNP
rs1045607271 2720 dbSNP
rs1283041877 2722 dbSNP
rs905556734 2723 dbSNP
rs1456840573 2726 dbSNP
rs1411103653 2730 dbSNP
rs546147264 2745 dbSNP
rs925956290 2746 dbSNP
rs1247029495 2751 dbSNP
rs1054508231 2752 dbSNP
rs892889155 2758 dbSNP
rs1229611709 2760 dbSNP
rs1449459079 2764 dbSNP
rs1208810704 2767 dbSNP
rs934941521 2767 dbSNP
rs11532 2776 dbSNP
rs1327917188 2784 dbSNP
rs1009956698 2787 dbSNP
rs1221391450 2795 dbSNP
rs1346330614 2810 dbSNP
rs1315486819 2818 dbSNP
rs1274568184 2834 dbSNP
rs1021168778 2844 dbSNP
rs902681602 2857 dbSNP
rs998466360 2863 dbSNP
rs1202759130 2864 dbSNP
rs934195631 2865 dbSNP
rs1029932384 2873 dbSNP
rs1386478545 2877 dbSNP
rs1276736593 2885 dbSNP
rs1416036341 2888 dbSNP
rs1425803537 2888 dbSNP
rs954416043 2889 dbSNP
rs1438300098 2891 dbSNP
rs752173834 2894 dbSNP
rs1452421929 2896 dbSNP
rs549496011 2898 dbSNP
rs553398278 2900 dbSNP
rs1391601523 2901 dbSNP
rs1017312300 2907 dbSNP
rs569706449 2908 dbSNP
rs1245591700 2913 dbSNP
rs538533171 2926 dbSNP
rs1443480787 2932 dbSNP
rs1278614554 2936 dbSNP
rs1344818073 2939 dbSNP
rs962859746 2939 dbSNP
rs972788070 2947 dbSNP
rs1182601908 2958 dbSNP
rs898816098 2960 dbSNP
rs555253037 2967 dbSNP
rs1448922613 2975 dbSNP
rs762023795 2989 dbSNP
rs1333477876 2995 dbSNP
rs949875704 2998 dbSNP
rs1047656756 3000 dbSNP
rs1448118629 3008 dbSNP
rs1372127714 3011 dbSNP
rs895693202 3020 dbSNP
rs1170853744 3032 dbSNP
rs1183086938 3036 dbSNP
rs1371741454 3039 dbSNP
rs1014097899 3042 dbSNP
rs1414365949 3047 dbSNP
rs15092 3048 dbSNP
rs970156191 3052 dbSNP
rs1356876916 3053 dbSNP
rs1000231340 3059 dbSNP
rs1033005135 3078 dbSNP
rs763689042 3079 dbSNP
rs1228934529 3089 dbSNP
rs1292375155 3089 dbSNP
rs1315389063 3089 dbSNP
rs73342486 3092 dbSNP
rs1225962899 3094 dbSNP
rs1299483099 3096 dbSNP
rs1352267883 3097 dbSNP
rs937216888 3099 dbSNP
rs751239237 3101 dbSNP
rs80248595 3102 dbSNP
rs1352368013 3105 dbSNP
rs922884803 3106 dbSNP
rs577253658 3107 dbSNP
rs189969446 3108 dbSNP
rs757496795 3111 dbSNP
rs955771841 3112 dbSNP
rs79077501 3114 dbSNP
rs1204378471 3121 dbSNP
rs1488797973 3125 dbSNP
rs1253242540 3130 dbSNP
rs1181904097 3131 dbSNP
rs1479886223 3137 dbSNP
rs901564063 3144 dbSNP
rs750945531 3147 dbSNP
rs1321384481 3150 dbSNP
rs1287738331 3162 dbSNP
rs998373083 3178 dbSNP
rs1230369008 3185 dbSNP
rs1331124018 3187 dbSNP
rs781616525 3196 dbSNP
rs1408964997 3197 dbSNP
rs1051661589 3198 dbSNP
rs1463676323 3218 dbSNP
rs1295100768 3219 dbSNP
rs890049532 3221 dbSNP
rs575982438 3224 dbSNP
rs541832561 3227 dbSNP
rs561613464 3230 dbSNP
rs943128256 3239 dbSNP
rs1037437080 3240 dbSNP
rs1413303673 3257 dbSNP
rs1159142463 3258 dbSNP
rs1417881108 3286 dbSNP
rs920314982 3296 dbSNP
rs962666862 3302 dbSNP
rs1488269599 3304 dbSNP
rs1251438388 3310 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
CLIP-seq Support 1 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000286800.3 | 3UTR | UUGUCUUUUGGCCAUAAGUGGGAAAGUUUUCUGUAUAUUGCAUAGCAUUACACAUUUAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
83 hsa-miR-4301 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT081134 LDLR low density lipoprotein receptor 2 4
MIRT090911 ARHGEF26 Rho guanine nucleotide exchange factor 26 2 2
MIRT229436 MECP2 methyl-CpG binding protein 2 2 2
MIRT274717 CPSF6 cleavage and polyadenylation specific factor 6 2 2
MIRT350957 BACH1 BTB domain and CNC homolog 1 2 2
MIRT386722 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT446022 PEX3 peroxisomal biogenesis factor 3 2 2
MIRT481303 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 14
MIRT483959 ZNF354B zinc finger protein 354B 2 6
MIRT495667 TUBAL3 tubulin alpha like 3 2 2
MIRT496554 TBX15 T-box 15 2 2
MIRT497702 ARL6IP6 ADP ribosylation factor like GTPase 6 interacting protein 6 2 2
MIRT498105 RMND5A required for meiotic nuclear division 5 homolog A 2 2
MIRT512535 SEMA4D semaphorin 4D 2 2
MIRT512556 MFN2 mitofusin 2 2 6
MIRT521465 RABGAP1 RAB GTPase activating protein 1 2 6
MIRT526236 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT526743 HLA-DOB major histocompatibility complex, class II, DO beta 2 2
MIRT527578 BRD7 bromodomain containing 7 2 4
MIRT528038 WT1 Wilms tumor 1 2 2
MIRT528267 GPRIN2 G protein regulated inducer of neurite outgrowth 2 2 2
MIRT528505 HTR7 5-hydroxytryptamine receptor 7 2 4
MIRT528758 RPS27 ribosomal protein S27 2 6
MIRT528999 IPO9 importin 9 2 2
MIRT529701 MRPL30 mitochondrial ribosomal protein L30 2 2
MIRT529781 C17orf82 chromosome 17 open reading frame 82 2 2
MIRT533797 TMEM119 transmembrane protein 119 2 6
MIRT535308 PHF12 PHD finger protein 12 2 2
MIRT535917 MKL2 MKL1/myocardin like 2 2 2
MIRT544892 OSBPL1A oxysterol binding protein like 1A 2 2
MIRT555423 PPIC peptidylprolyl isomerase C 2 2
MIRT562068 KLHL15 kelch like family member 15 2 2
MIRT565623 SLC31A1 solute carrier family 31 member 1 2 2
MIRT565661 SIX1 SIX homeobox 1 2 2
MIRT570138 IL1RL2 interleukin 1 receptor like 2 2 2
MIRT571045 YRDC yrdC N6-threonylcarbamoyltransferase domain containing 2 2
MIRT621232 LMAN1 lectin, mannose binding 1 2 2
MIRT622272 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT623844 GAN gigaxonin 2 2
MIRT626158 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT626464 CMKLR1 chemerin chemokine-like receptor 1 2 2
MIRT632087 ALDH1A2 aldehyde dehydrogenase 1 family member A2 2 2
MIRT637243 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT642710 FGFR1OP2 FGFR1 oncogene partner 2 2 2
MIRT643611 KANSL3 KAT8 regulatory NSL complex subunit 3 2 2
MIRT644270 PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 2 2
MIRT645470 SPIN3 spindlin family member 3 2 2
MIRT649193 DNPEP aspartyl aminopeptidase 2 2
MIRT650776 POP4 POP4 homolog, ribonuclease P/MRP subunit 2 2
MIRT651345 ZC2HC1C zinc finger C2HC-type containing 1C 2 2
MIRT652237 TRAPPC3L trafficking protein particle complex 3 like 2 2
MIRT652587 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT654591 PURA purine rich element binding protein A 2 2
MIRT654649 PTAFR platelet activating factor receptor 2 2
MIRT656842 KLF7 Kruppel like factor 7 2 2
MIRT657209 IKZF2 IKAROS family zinc finger 2 2 2
MIRT658513 ETV3 ETS variant 3 2 2
MIRT659448 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT668816 CYLD CYLD lysine 63 deubiquitinase 2 2
MIRT669067 CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 2 2
MIRT677711 ELOF1 elongation factor 1 homolog 2 4
MIRT687146 PTPN12 protein tyrosine phosphatase, non-receptor type 12 2 2
MIRT698498 THOC2 THO complex 2 2 2
MIRT707930 PPP1R3D protein phosphatase 1 regulatory subunit 3D 4 2
MIRT708737 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT710031 POLL DNA polymerase lambda 2 2
MIRT712175 STK4 serine/threonine kinase 4 2 2
MIRT715297 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT716892 AGPAT6 glycerol-3-phosphate acyltransferase 4 2 2
MIRT717378 RBM41 RNA binding motif protein 41 2 2
MIRT718082 CLIC5 chloride intracellular channel 5 2 2
MIRT718721 ANKRD18A ankyrin repeat domain 18A 2 2
MIRT719152 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT719224 CAMK4 calcium/calmodulin dependent protein kinase IV 2 2
MIRT719528 SRCIN1 SRC kinase signaling inhibitor 1 2 2
MIRT719861 KLF2 Kruppel like factor 2 2 2
MIRT720326 CAMK2G calcium/calmodulin dependent protein kinase II gamma 2 2
MIRT721596 SREBF1 sterol regulatory element binding transcription factor 1 2 2
MIRT722020 NEBL nebulette 2 2
MIRT722484 QSOX1 quiescin sulfhydryl oxidase 1 2 2
MIRT722614 TEAD1 TEA domain transcription factor 1 2 2
MIRT723664 RPTN repetin 2 2
MIRT723939 SVOP SV2 related protein 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4301 Cisplatin 5460033 NSC119875 approved sensitive High Hepatocellular Carcinoma cell line (Hep3B, 97L)
hsa-miR-4301 Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-mir-4301 Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-mir-4301 Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-4301 Doxorubicin 31703 NSC123127 approved sensitive cell line (W1)
hsa-mir-4301 Methotrexate 126941 NSC740 approved sensitive cell line (W1)
hsa-mir-4301 Topotecan 60699 NSC609699 approved sensitive cell line (W1)
hsa-miR-4301 Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-4301 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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