miRTarBase - #MIRT358701


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pre-miRNA Information
pre-miRNA hsa-mir-452   
Genomic Coordinates chrX: 151959628 - 151959712
Synonyms MIRN452, hsa-mir-452, MIR452
Description Homo sapiens miR-452 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies . The 5' end of the miRNA may be offset with respect to previous annotations.
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-452-3p
Sequence 58| CUCAUCUGCAAAGAAGUAAGUG |79
Evidence Experimental
Experiments Array-cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 12 X - 151959644 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs757928550 3 dbSNP
rs1324216965 6 dbSNP
rs1390793899 13 dbSNP
rs899383242 17 dbSNP
rs747858567 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SUB1   
Synonyms P15, PC4, p14
Description SUB1 homolog, transcriptional regulator
Transcript NM_006713   
Expression
Putative miRNA Targets on SUB1
3'UTR of SUB1
(miRNA target sites are highlighted)		 
>SUB1|NM_006713|3'UTR
   1 AATTCGAGCCATATAAATAAAACCTGTACTGTTCTAGTTGTTTTAATCTGTCTTTTTACATTGGCTTTTGTTTTCTAAAT
  81 GTTCTCCAAGCTATTGTATGTTTGGATTGCAGAAGAATTTGTAAGATGAATACTTTTTTTTAATGTGCATTATTAAAAAT
 161 ATTGAGTGAAGCTAATTGTCAACTTTATTAAGGATTACTTTGTCTGCCCACCACCTAGTGTAAAATAAAATCAAGTAATA
 241 CAATCTTAACTGTTGTGGCCTTTTTTGATCATAAGAGTTGGTACTGTTTAAGGCCAAAAGTAACAGTTTTTATAGATCTT
 321 TTAGTTTCAACTCAGCTTTTACAATAAAAAGGATTTGTATTGCATTGAGTTTATAAACTTTTGGTTTGTGAACTTCATAT
 401 TTGATCTTTTCTCTTCCAATCAAATGTCTAGGCTTGTTTGACTTCCACCCCCAATGGTTTTTCACTCTTTTTATTTACTT
 481 CATTTTCCTTTAATAACTTAATCTCTTCATGTTCAGTTTTTACTTCACTCTTTATTCTTTTCTTTGATTATGGTATGCTT
 561 ATTTGGAAAGTCAGTGAAACTGTCAAAATGTTATCTCAATAAGATACTTATATGAGAACTACAATCACCGAATCTACTGT
 641 ATTCAATATTAGCAGATCTAATTTGATAAACAACATGGCTTGTGTGAAAACTGAGCAGGTGTTTGTTTACCCATAGTGTT
 721 CTGTGTAGTTATTGCTTAGTCTGCAGAAAATAATGACTTAGATGAGATGTCTGACTTGCTTTCACTTATTAAACATGTTC
 801 ACCATGGGATGATGTCTGTAACATCAGATATTGTTCAACTAGACTAGGATTTAATAAAAATTGTGAAAGCTTACTGGCCT
 881 AACATTTTATTTTATAATATTGGGTATGAATTATATGTAGCCAGAGATGTCATTAAGCTTTACTGTTATAGTAGGTAATA
 961 TGGTTAGTTTGTAGGGAAAAGAGCATATGAGCACATGCTTGTGTATTTTGGCCTTTGCCCCAGTAGAACAGACCAATGGC
1041 ATTCTAGACTTGATGATACTAAGTTTTAGCAGACACTAGTAAGTGGTTTGTATTTAACCATACTGATGAAGCAGACAGAT
1121 TGAGGCACAGATTTTAGTGGCTTTGTGGCAATAAATAGGGCATGGTGTGCCTTAGGAAAAGAATGTTTATAAAGGGAATT
1201 ATAACTGAAATTAAAGGAGGCGGCAGTGAAGAGGAAATAATTCTCTTCTATCTAAATGATATACATATGATATTTTGAGA
1281 TTTTTATAACAGCAGTGGAACACAATTCTAGGTAGAGTAGAAAAAGGAAAGTTTTAAAGACATATAAAAGATTCTTGTTG
1361 ACAAATTATTTTTGGTAGCAAATCTCAAATGGTTACCTGCTATTAAGGTCTGCCATATTAGAGTTTTGCACTATTTTGCT
1441 ACCAAGTTTGATTCATACATCTAAAACATTTTGTAGTTACTTGTCAAGGACTTAATTTGAAAATCATTTGCCAGGCCACA
1521 TAGTTATCAATTTTTTTTTCTATCAGCTATTCTGTTGTATTTCTAAAACATTTTTTAGATGACTTTTTAAAGTATATTTA
1601 GCAGTAACCTTATGAGGTTCAAATTGGTAAATCTCTTGTAATTTAGCCTTCATCGAATAATAGGTACCAGTGTATTAAAA
1681 ATGTGTATTTTTTGCAGCCCCTTGAACCAGAGTAGGTTCAGAGAAACTCCCAAAGTTTGTACTTTAGACACATCATGCTT
1761 GATTGGTAACTTCCCTCCTTTTTTGGGGAACATGTTTGTGTCCTATTAACTTAATTGGATAGATTTTTAAATATTTCTTA
1841 TTTTTGGCACACGGAAAGGGTAGTTCGAGTACAGAACTTTGATTTTTGGTGTAGATGCAGAGGGAATGATGGGTAAATTT
1921 CCTAGGTTTATGTGAATTTAGGGGGTGTATGCATTTTGAAACAATCTACTAACAGATGGTGCTGAAATCTATTACCTACA
2001 TGTTTTCTAGTTGTTCAGCATTATGTTAATGAAGCCTCCATATAAGGAGTGTTTCTCTGGCACAGTTGGTAAGTTGACTG
2081 CTAACTTCATTTAAATGTGTTACTGGATATGCAGTATACTGAAATTATTAATCAGTTTGTGTATAGGAAAAGAGAACTGG
2161 GTTAAAAGCAAATTAACTTGTTCTGAAAAGAAAGTATAGATTAATTTTGTTTTCTGTTTAAATTTTATCTCCTTGGTAAA
2241 GATTTTTTTTTCCTGGGCAGAAAACTTGGCATTTTTAGGCGTAGATACCTTACCTTACAATGCCAAAATGAATTTAATTC
2321 CAGTACTCAGGTTTTTCCCTTTAACAGACTCTATGTGTATCAGGGCTTTCTAATGGGTTTTTCCTCTTCGTTTTTAAAAT
2401 GTGAGTAGCATTTGACCAATTTCCAGTGCTCTTAGCATTTTACTTAAAGAACAACCACTACAAAAGAAAATCTTTGTAAT
2481 TTGATTGTCTTTTGCTTTGCTTCATTAATGCCTAAGAACTTAAGAATACTCCTACCTCATTAGCTACTCAAGATGCTGTG
2561 ACGATCAAATCTATTCTACATAATGCGTTTAGAAACAAAGACTTGGGTGAAAAATGAAATAAGTATATTCTGACTTGGCT
2641 ATTGAGGGGAAAATTCAGTATTAAGTGTTCCTCACAGGAGATATGTTAGCAGAATACTATAAAAGTTTGAAATTTTTAAA
2721 AAGTAAAAGTACTTAAATTTAGGTATCTCTCCTGAAATTCTTTGCAGTTCATTTTTTATGGCAGTTAATCCAGTGAAACA
2801 CTCAAAAGTTTTTTTTTTTTTAAAAGTGTTTTTCCAGATAAACTGTAGGGTGAACATTCACATAATCACAAATATGTAAT
2881 TCTGTAATTGTGGAATGCTTGTATGCTTTGTTTTCGTACATCTTCCATGGAGATGTCTGAATATAATACTCCATCTGTGA
2961 ATATTTTAAATGTTGAAATAAAAGTAAGAAATGTGAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gugaaUGAAGAAACGUCUACUc 5'
               || |:||| :|||||| 
Target 5' ctaaaACATTTTT-TAGATGAc 3'
 1563 - 1583 144.00 -7.30
2 
miRNA  3' guGAAUGAAGAA--ACGUCUACuc 5'
            :||: ||:||  ||:|||||  
Target 5' acTTTGATTTTTGGTGTAGATGca 3'
 1876 - 1899 134.00 -12.30
3 
miRNA  3' gugaAUGAAGA---AACGUCUACUc 5'
              ||: |:|   ||||||| || 
Target 5' attgTATGTTTGGATTGCAGAAGAa 3'
 93 - 117 130.00 -7.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN8892365 6 COSMIC
COSN30476101 25 COSMIC
COSN4611927 61 COSMIC
COSN26562489 71 COSMIC
COSN31550509 146 COSMIC
COSN21685038 203 COSMIC
COSN31526822 216 COSMIC
COSN15022545 251 COSMIC
COSN20181187 400 COSMIC
COSN6294378 463 COSMIC
COSN6294379 532 COSMIC
COSN31962394 643 COSMIC
COSN21856339 796 COSMIC
COSN9432899 855 COSMIC
COSN20061901 1177 COSMIC
COSN4849363 1533 COSMIC
COSN4849364 1535 COSMIC
COSN26114064 1829 COSMIC
COSN28285188 2437 COSMIC
COSN15011723 2634 COSMIC
COSN20101088 2822 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1252050665 5 dbSNP
rs181767182 6 dbSNP
rs11555316 9 dbSNP
rs777196615 10 dbSNP
rs746402573 14 dbSNP
rs200371394 16 dbSNP
rs550851148 18 dbSNP
rs1268879788 24 dbSNP
rs201891162 31 dbSNP
rs769055508 35 dbSNP
rs186461434 37 dbSNP
rs748316653 39 dbSNP
rs1162594803 41 dbSNP
rs1241307082 47 dbSNP
rs546898304 50 dbSNP
rs11555320 54 dbSNP
rs973338215 71 dbSNP
rs371304539 81 dbSNP
rs1440261900 91 dbSNP
rs188149821 94 dbSNP
rs1302322510 95 dbSNP
rs535562493 97 dbSNP
rs555858057 99 dbSNP
rs575706375 102 dbSNP
rs1382947654 105 dbSNP
rs1408888758 108 dbSNP
rs928695726 111 dbSNP
rs763058507 114 dbSNP
rs1053493755 121 dbSNP
rs1420487095 122 dbSNP
rs1180737763 133 dbSNP
rs1459953315 134 dbSNP
rs1325613482 138 dbSNP
rs1216780058 142 dbSNP
rs891786563 146 dbSNP
rs1464221025 147 dbSNP
rs1258736595 148 dbSNP
rs947414452 150 dbSNP
rs766491877 153 dbSNP
rs1312148566 155 dbSNP
rs1243804985 163 dbSNP
rs751681405 168 dbSNP
rs1337886528 173 dbSNP
rs1435003766 178 dbSNP
rs1043308907 179 dbSNP
rs1290972916 183 dbSNP
rs15075 185 dbSNP
rs900781001 187 dbSNP
rs996315801 195 dbSNP
rs760292632 201 dbSNP
rs867916895 205 dbSNP
rs1448780772 208 dbSNP
rs1259459055 209 dbSNP
rs557253145 210 dbSNP
rs1186715277 218 dbSNP
rs1486328762 226 dbSNP
rs1265024556 227 dbSNP
rs1030521014 228 dbSNP
rs1361764200 230 dbSNP
rs577213963 231 dbSNP
rs1228372544 235 dbSNP
rs1261532603 251 dbSNP
rs759831033 252 dbSNP
rs545952753 261 dbSNP
rs890164367 263 dbSNP
rs1477038733 267 dbSNP
rs1298223942 269 dbSNP
rs767669622 272 dbSNP
rs149354159 274 dbSNP
rs528729177 285 dbSNP
rs377098975 289 dbSNP
rs7710785 290 dbSNP
rs1163643249 291 dbSNP
rs561484277 296 dbSNP
rs973067059 312 dbSNP
rs1429075634 313 dbSNP
rs1162800106 317 dbSNP
rs1023495063 322 dbSNP
rs969291447 323 dbSNP
rs1266402192 325 dbSNP
rs1197604863 331 dbSNP
rs1454545261 350 dbSNP
rs1292638645 351 dbSNP
rs1204470390 360 dbSNP
rs531544451 367 dbSNP
rs1253542343 370 dbSNP
rs530383584 373 dbSNP
rs1281759233 404 dbSNP
rs1402773000 414 dbSNP
rs1346972507 417 dbSNP
rs1384058450 420 dbSNP
rs1390253723 427 dbSNP
rs1394254765 431 dbSNP
rs1169644017 455 dbSNP
rs1462420126 457 dbSNP
rs1376904321 459 dbSNP
rs748759438 468 dbSNP
rs1173947020 470 dbSNP
rs927825710 472 dbSNP
rs935194347 479 dbSNP
rs988908861 489 dbSNP
rs1436089101 494 dbSNP
rs763839121 496 dbSNP
rs1294834315 497 dbSNP
rs1196946563 498 dbSNP
rs1356035175 498 dbSNP
rs947394443 504 dbSNP
rs1043091772 506 dbSNP
rs550162049 509 dbSNP
rs1310009022 511 dbSNP
rs922153542 513 dbSNP
rs1216137904 529 dbSNP
rs543571609 531 dbSNP
rs564410575 534 dbSNP
rs1330282529 547 dbSNP
rs1213488469 556 dbSNP
rs1051901627 558 dbSNP
rs1334467037 573 dbSNP
rs1470802413 575 dbSNP
rs1430256345 578 dbSNP
rs1258601517 586 dbSNP
rs180947371 589 dbSNP
rs1005503556 591 dbSNP
rs1182582146 594 dbSNP
rs1442381418 597 dbSNP
rs1241785343 598 dbSNP
rs1205970439 604 dbSNP
rs753588321 605 dbSNP
rs1267876058 610 dbSNP
rs1222899874 611 dbSNP
rs1410326119 612 dbSNP
rs1239073687 613 dbSNP
rs879878766 614 dbSNP
rs1381959572 622 dbSNP
rs1419739511 630 dbSNP
rs1454511971 631 dbSNP
rs750368102 632 dbSNP
rs1158393070 639 dbSNP
rs1317351463 643 dbSNP
rs1358878492 647 dbSNP
rs549934155 659 dbSNP
rs898939798 664 dbSNP
rs1383455565 666 dbSNP
rs1186028297 677 dbSNP
rs547305875 694 dbSNP
rs566930311 696 dbSNP
rs1285840842 700 dbSNP
rs536093167 700 dbSNP
rs1023277366 703 dbSNP
rs1358195190 713 dbSNP
rs969242420 714 dbSNP
rs1248147647 720 dbSNP
rs1383400959 728 dbSNP
rs1003406569 737 dbSNP
rs1035387960 748 dbSNP
rs1328440672 753 dbSNP
rs1319302795 758 dbSNP
rs1375804910 760 dbSNP
rs956547961 762 dbSNP
rs988406593 763 dbSNP
rs148120673 767 dbSNP
rs1425876586 786 dbSNP
rs1419359730 787 dbSNP
rs1300997925 790 dbSNP
rs757791362 796 dbSNP
rs1476554611 800 dbSNP
rs1243054224 802 dbSNP
rs1156574416 808 dbSNP
rs779639132 810 dbSNP
rs1490079183 828 dbSNP
rs73063661 829 dbSNP
rs1224021926 832 dbSNP
rs1305605654 838 dbSNP
rs142542213 839 dbSNP
rs1272135616 841 dbSNP
rs558207115 843 dbSNP
rs191118736 844 dbSNP
rs539339484 845 dbSNP
rs1270526232 862 dbSNP
rs553263733 863 dbSNP
rs1208719221 884 dbSNP
rs1052017458 888 dbSNP
rs1305050863 889 dbSNP
rs912156045 902 dbSNP
rs1405568572 904 dbSNP
rs746603157 914 dbSNP
rs34935685 921 dbSNP
rs940857029 923 dbSNP
rs1481212843 949 dbSNP
rs372936341 950 dbSNP
rs1420735636 952 dbSNP
rs1378509135 957 dbSNP
rs1176128079 966 dbSNP
rs1479924599 967 dbSNP
rs183431569 971 dbSNP
rs1174475991 972 dbSNP
rs994550162 980 dbSNP
rs1044826141 982 dbSNP
rs1202411135 985 dbSNP
rs186749563 987 dbSNP
rs190518348 988 dbSNP
rs575015551 992 dbSNP
rs1321682023 996 dbSNP
rs1285355496 998 dbSNP
rs1003185589 999 dbSNP
rs1372772831 1002 dbSNP
rs543769497 1006 dbSNP
rs1034930135 1007 dbSNP
rs1442777483 1017 dbSNP
rs1355586340 1018 dbSNP
rs1336511640 1021 dbSNP
rs563722006 1022 dbSNP
rs1426777402 1023 dbSNP
rs532971757 1024 dbSNP
rs781049528 1028 dbSNP
rs1373980845 1032 dbSNP
rs376023071 1033 dbSNP
rs968757545 1035 dbSNP
rs1303679925 1037 dbSNP
rs1346614985 1039 dbSNP
rs1238648696 1051 dbSNP
rs1202798998 1057 dbSNP
rs1264760156 1058 dbSNP
rs1211150764 1069 dbSNP
rs1316528441 1073 dbSNP
rs1305002796 1075 dbSNP
rs1225491523 1078 dbSNP
rs751987630 1079 dbSNP
rs1314884430 1080 dbSNP
rs1461925977 1082 dbSNP
rs1451093389 1083 dbSNP
rs978835053 1084 dbSNP
rs1295172242 1087 dbSNP
rs1382905777 1091 dbSNP
rs1466259926 1094 dbSNP
rs1381652522 1097 dbSNP
rs1296383512 1099 dbSNP
rs773377742 1101 dbSNP
rs1344187443 1103 dbSNP
rs1231665551 1105 dbSNP
rs560881738 1109 dbSNP
rs763068190 1114 dbSNP
rs1335855736 1119 dbSNP
rs1216117362 1122 dbSNP
rs1420280084 1127 dbSNP
rs1259423348 1130 dbSNP
rs1261031992 1141 dbSNP
rs770285674 1142 dbSNP
rs1484609331 1146 dbSNP
rs1442678715 1156 dbSNP
rs1204107572 1160 dbSNP
rs1244789860 1163 dbSNP
rs1261798242 1166 dbSNP
rs1182197701 1167 dbSNP
rs766267931 1172 dbSNP
rs1185298884 1182 dbSNP
rs1416925704 1184 dbSNP
rs1259126072 1190 dbSNP
rs1475380076 1197 dbSNP
rs1166841850 1200 dbSNP
rs1362062352 1201 dbSNP
rs1352596271 1202 dbSNP
rs1291118792 1213 dbSNP
rs922053168 1214 dbSNP
rs1385565013 1220 dbSNP
rs953343308 1221 dbSNP
rs987905712 1222 dbSNP
rs1252616870 1223 dbSNP
rs773794751 1224 dbSNP
rs763535428 1225 dbSNP
rs1360838526 1229 dbSNP
rs1286821811 1231 dbSNP
rs1477132288 1236 dbSNP
rs1360666492 1241 dbSNP
rs529427507 1242 dbSNP
rs1421341228 1246 dbSNP
rs1386965103 1251 dbSNP
rs1188016310 1252 dbSNP
rs1410507567 1256 dbSNP
rs1188568110 1259 dbSNP
rs549602901 1259 dbSNP
rs1488721159 1263 dbSNP
rs1419870953 1267 dbSNP
rs1169852323 1269 dbSNP
rs372446711 1281 dbSNP
rs1362238230 1284 dbSNP
rs1462561182 1287 dbSNP
rs569347157 1291 dbSNP
rs972219959 1295 dbSNP
rs1306178035 1308 dbSNP
rs1298154770 1309 dbSNP
rs1401508630 1313 dbSNP
rs1325922106 1326 dbSNP
rs548259228 1331 dbSNP
rs1367374730 1332 dbSNP
rs930852353 1339 dbSNP
rs531860025 1341 dbSNP
rs1461409903 1342 dbSNP
rs1371178874 1345 dbSNP
rs1044774292 1347 dbSNP
rs1478282926 1352 dbSNP
rs904980238 1355 dbSNP
rs1490879001 1357 dbSNP
rs1268125458 1364 dbSNP
rs1330172515 1369 dbSNP
rs10472813 1387 dbSNP
rs892342355 1392 dbSNP
rs568099548 1406 dbSNP
rs1219582398 1409 dbSNP
rs571531947 1410 dbSNP
rs1318177551 1413 dbSNP
rs1221299224 1414 dbSNP
rs1272330014 1415 dbSNP
rs1009904429 1416 dbSNP
rs1394188314 1418 dbSNP
rs1333135632 1423 dbSNP
rs1465885769 1432 dbSNP
rs1363068135 1437 dbSNP
rs1022247782 1439 dbSNP
rs903688228 1441 dbSNP
rs1218624973 1447 dbSNP
rs1378319173 1447 dbSNP
rs78936561 1448 dbSNP
rs1253219453 1452 dbSNP
rs1347608456 1455 dbSNP
rs1029072070 1460 dbSNP
rs755375549 1474 dbSNP
rs953455876 1474 dbSNP
rs1201442968 1479 dbSNP
rs774454412 1490 dbSNP
rs759579964 1498 dbSNP
rs552948164 1514 dbSNP
rs1237633261 1520 dbSNP
rs1333912032 1520 dbSNP
rs3204139 1521 dbSNP
rs1272577411 1524 dbSNP
rs1447404964 1525 dbSNP
rs1450123191 1526 dbSNP
rs1195559997 1528 dbSNP
rs1019367088 1530 dbSNP
rs146152836 1531 dbSNP
rs530506178 1531 dbSNP
rs869265087 1531 dbSNP
rs962287477 1531 dbSNP
rs972721854 1541 dbSNP
rs566759740 1543 dbSNP
rs76997867 1544 dbSNP
rs1475614310 1545 dbSNP
rs1185757798 1547 dbSNP
rs1443798994 1562 dbSNP
rs78160174 1564 dbSNP
rs535265688 1566 dbSNP
rs1278803928 1571 dbSNP
rs555157400 1596 dbSNP
rs1204182166 1600 dbSNP
rs920867782 1601 dbSNP
rs1287506979 1607 dbSNP
rs1240835036 1613 dbSNP
rs1381895895 1614 dbSNP
rs1312676855 1621 dbSNP
rs1192580414 1625 dbSNP
rs930798724 1627 dbSNP
rs1317988072 1628 dbSNP
rs980918660 1631 dbSNP
rs926348374 1638 dbSNP
rs1159297714 1644 dbSNP
rs939098451 1652 dbSNP
rs575129077 1653 dbSNP
rs1056098867 1655 dbSNP
rs74579454 1656 dbSNP
rs1165049527 1658 dbSNP
rs1473368612 1662 dbSNP
rs1241878517 1663 dbSNP
rs543880503 1664 dbSNP
rs892119181 1665 dbSNP
rs945103644 1668 dbSNP
rs557476167 1669 dbSNP
rs1216636215 1671 dbSNP
rs1358662572 1677 dbSNP
rs1289427397 1686 dbSNP
rs1403294020 1687 dbSNP
rs1319866721 1688 dbSNP
rs1356859585 1692 dbSNP
rs1346228484 1706 dbSNP
rs1269359565 1711 dbSNP
rs903804379 1712 dbSNP
rs1342569085 1715 dbSNP
rs996654725 1717 dbSNP
rs748160993 1720 dbSNP
rs577556301 1721 dbSNP
rs1406437926 1727 dbSNP
rs889167106 1731 dbSNP
rs183099513 1733 dbSNP
rs1476647317 1746 dbSNP
rs560578974 1749 dbSNP
rs1193762777 1750 dbSNP
rs529613835 1751 dbSNP
rs1490063000 1755 dbSNP
rs1046680 1757 dbSNP
rs1019067612 1758 dbSNP
rs761532656 1762 dbSNP
rs765033258 1767 dbSNP
rs750313227 1769 dbSNP
rs1354314552 1774 dbSNP
rs1212540863 1776 dbSNP
rs1320273906 1777 dbSNP
rs962334949 1778 dbSNP
rs563059623 1779 dbSNP
rs972118633 1779 dbSNP
rs1027834433 1780 dbSNP
rs952313656 1781 dbSNP
rs980864625 1784 dbSNP
rs1343768253 1788 dbSNP
rs1295330752 1792 dbSNP
rs1446579299 1795 dbSNP
rs926799401 1798 dbSNP
rs570684743 1801 dbSNP
rs1476168424 1805 dbSNP
rs1401478776 1806 dbSNP
rs570380088 1806 dbSNP
rs766268162 1807 dbSNP
rs751059030 1821 dbSNP
rs1471521453 1823 dbSNP
rs539406320 1826 dbSNP
rs1043427661 1832 dbSNP
rs925167153 1834 dbSNP
rs551904946 1840 dbSNP
rs1408286974 1841 dbSNP
rs187826324 1842 dbSNP
rs539358402 1848 dbSNP
rs116248118 1853 dbSNP
rs869052687 1853 dbSNP
rs566614458 1854 dbSNP
rs34763799 1855 dbSNP
rs1008084726 1859 dbSNP
rs1334075422 1861 dbSNP
rs1339152121 1864 dbSNP
rs139970366 1867 dbSNP
rs1280158823 1873 dbSNP
rs1373256006 1878 dbSNP
rs1353299333 1882 dbSNP
rs897921708 1883 dbSNP
rs993882299 1884 dbSNP
rs1378177491 1894 dbSNP
rs555269796 1916 dbSNP
rs1469000668 1920 dbSNP
rs1357025873 1936 dbSNP
rs1177624530 1946 dbSNP
rs1414606640 1950 dbSNP
rs1406588354 1965 dbSNP
rs1176749933 1969 dbSNP
rs1441429537 1971 dbSNP
rs1238203581 1972 dbSNP
rs1182697106 1974 dbSNP
rs552896173 1974 dbSNP
rs1486521441 1975 dbSNP
rs1482406075 1982 dbSNP
rs952261712 1987 dbSNP
rs568708487 1992 dbSNP
rs1316474185 1994 dbSNP
rs1283946083 1999 dbSNP
rs1243006570 2001 dbSNP
rs1002401604 2003 dbSNP
rs1033933285 2014 dbSNP
rs961143416 2017 dbSNP
rs992370198 2023 dbSNP
rs913615553 2030 dbSNP
rs537695407 2032 dbSNP
rs966504431 2035 dbSNP
rs749651890 2039 dbSNP
rs1156261663 2041 dbSNP
rs1421465763 2043 dbSNP
rs1380773232 2056 dbSNP
rs141802392 2059 dbSNP
rs1421908262 2062 dbSNP
rs557521337 2083 dbSNP
rs1257996503 2084 dbSNP
rs1438742588 2085 dbSNP
rs1156440702 2086 dbSNP
rs979053325 2087 dbSNP
rs1261171297 2088 dbSNP
rs1397339945 2090 dbSNP
rs1218826983 2096 dbSNP
rs924949495 2099 dbSNP
rs1435730448 2107 dbSNP
rs1243234740 2108 dbSNP
rs1323927084 2109 dbSNP
rs932340932 2116 dbSNP
rs566649895 2125 dbSNP
rs1339391331 2126 dbSNP
rs1049654206 2138 dbSNP
rs869105462 2140 dbSNP
rs912508431 2145 dbSNP
rs1360599160 2146 dbSNP
rs1400717013 2147 dbSNP
rs1456310681 2148 dbSNP
rs1370019220 2150 dbSNP
rs1393602298 2151 dbSNP
rs1165168882 2152 dbSNP
rs1329666824 2154 dbSNP
rs1421685095 2161 dbSNP
rs535323994 2169 dbSNP
rs869239204 2170 dbSNP
rs1444916343 2172 dbSNP
rs1488690164 2181 dbSNP
rs1268237739 2183 dbSNP
rs1208618522 2188 dbSNP
rs577676293 2192 dbSNP
rs771443848 2197 dbSNP
rs533519205 2201 dbSNP
rs1204196392 2203 dbSNP
rs1348788049 2205 dbSNP
rs1275983809 2213 dbSNP
rs1220073167 2228 dbSNP
rs1233725747 2233 dbSNP
rs869282319 2238 dbSNP
rs1036884766 2242 dbSNP
rs1342827761 2243 dbSNP
rs869242973 2243 dbSNP
rs1385040264 2258 dbSNP
rs1197455589 2259 dbSNP
rs1293914007 2261 dbSNP
rs17538420 2264 dbSNP
rs1397847056 2272 dbSNP
rs745960043 2273 dbSNP
rs993548854 2281 dbSNP
rs113232575 2282 dbSNP
rs1428716090 2284 dbSNP
rs775635236 2291 dbSNP
rs1435438420 2301 dbSNP
rs1268585925 2320 dbSNP
rs1433357901 2321 dbSNP
rs1195727679 2324 dbSNP
rs1456761111 2330 dbSNP
rs191180947 2333 dbSNP
rs1200188203 2343 dbSNP
rs1376249817 2346 dbSNP
rs1230366915 2347 dbSNP
rs1002185791 2349 dbSNP
rs1034336748 2352 dbSNP
rs1301980399 2352 dbSNP
rs961003520 2353 dbSNP
rs1399733497 2354 dbSNP
rs1466354260 2357 dbSNP
rs1401694177 2358 dbSNP
rs182498169 2360 dbSNP
rs1014150534 2361 dbSNP
rs1467706637 2378 dbSNP
rs1021125510 2385 dbSNP
rs966828931 2390 dbSNP
rs1327941916 2400 dbSNP
rs1372030555 2402 dbSNP
rs979169363 2403 dbSNP
rs760911183 2406 dbSNP
rs188017934 2408 dbSNP
rs1329118835 2410 dbSNP
rs953679882 2420 dbSNP
rs545629872 2421 dbSNP
rs1229602265 2423 dbSNP
rs1346584194 2426 dbSNP
rs985137385 2430 dbSNP
rs912445749 2433 dbSNP
rs1351348220 2438 dbSNP
rs1311198920 2440 dbSNP
rs1447161618 2452 dbSNP
rs1317159457 2453 dbSNP
rs764978524 2461 dbSNP
rs773028818 2463 dbSNP
rs1397981882 2470 dbSNP
rs1403054992 2473 dbSNP
rs565202672 2476 dbSNP
rs1158084957 2481 dbSNP
rs369960350 2490 dbSNP
rs1418434244 2493 dbSNP
rs1382641283 2494 dbSNP
rs1196228020 2510 dbSNP
rs1159637870 2513 dbSNP
rs943972069 2517 dbSNP
rs762706413 2525 dbSNP
rs972941916 2526 dbSNP
rs1185009727 2527 dbSNP
rs766334647 2530 dbSNP
rs1256266961 2533 dbSNP
rs1215184731 2534 dbSNP
rs569708134 2535 dbSNP
rs1288156825 2540 dbSNP
rs1049114938 2546 dbSNP
rs1355438656 2547 dbSNP
rs574855709 2550 dbSNP
rs1265777567 2554 dbSNP
rs1282183425 2556 dbSNP
rs192691456 2562 dbSNP
rs887893241 2563 dbSNP
rs937986376 2564 dbSNP
rs1297674500 2574 dbSNP
rs1194752811 2576 dbSNP
rs1055153264 2577 dbSNP
rs896691019 2584 dbSNP
rs751456248 2585 dbSNP
rs1412113714 2587 dbSNP
rs1165312785 2588 dbSNP
rs1473580237 2596 dbSNP
rs1021660690 2597 dbSNP
rs1192473940 2597 dbSNP
rs1476587907 2606 dbSNP
rs1477100930 2608 dbSNP
rs1167232336 2611 dbSNP
rs149884500 2613 dbSNP
rs535201598 2627 dbSNP
rs1450923713 2629 dbSNP
rs1457641625 2632 dbSNP
rs1211355961 2636 dbSNP
rs1291990938 2642 dbSNP
rs869124712 2650 dbSNP
rs555500059 2653 dbSNP
rs869167721 2653 dbSNP
rs1388397594 2657 dbSNP
rs1383716758 2659 dbSNP
rs1001061728 2676 dbSNP
rs1217021075 2678 dbSNP
rs1339791151 2682 dbSNP
rs144936817 2685 dbSNP
rs1278874737 2688 dbSNP
rs1294646900 2694 dbSNP
rs1436415104 2695 dbSNP
rs1348587797 2699 dbSNP
rs1321779147 2700 dbSNP
rs953793419 2705 dbSNP
rs985085199 2709 dbSNP
rs869197678 2719 dbSNP
rs1019282470 2731 dbSNP
rs1263318511 2741 dbSNP
rs1486610798 2743 dbSNP
rs965449120 2744 dbSNP
rs1186544470 2746 dbSNP
rs1262872046 2746 dbSNP
rs869162096 2746 dbSNP
rs1477666198 2757 dbSNP
rs1487618488 2758 dbSNP
rs1200913193 2761 dbSNP
rs1190670823 2764 dbSNP
rs771893034 2767 dbSNP
rs1197034061 2772 dbSNP
rs972670923 2772 dbSNP
rs918521277 2773 dbSNP
rs1320203724 2782 dbSNP
rs931136551 2787 dbSNP
rs1365569237 2789 dbSNP
rs1162694288 2790 dbSNP
rs1277174818 2791 dbSNP
rs1365780107 2791 dbSNP
rs1420493004 2792 dbSNP
rs1437776904 2792 dbSNP
rs1298620468 2793 dbSNP
rs1329678645 2794 dbSNP
rs1359634693 2803 dbSNP
rs1463756635 2804 dbSNP
rs983934833 2804 dbSNP
rs909277447 2806 dbSNP
rs1174299270 2809 dbSNP
rs1239761469 2809 dbSNP
rs35817466 2809 dbSNP
rs398108794 2809 dbSNP
rs565479561 2809 dbSNP
rs938100648 2811 dbSNP
rs1379714349 2814 dbSNP
rs869254482 2819 dbSNP
rs201176161 2822 dbSNP
rs752354207 2822 dbSNP
rs79438029 2823 dbSNP
rs1309900368 2824 dbSNP
rs869131593 2826 dbSNP
rs1318387419 2829 dbSNP
rs896480547 2834 dbSNP
rs1220345785 2837 dbSNP
rs1353554820 2838 dbSNP
rs1449378016 2846 dbSNP
rs949456292 2847 dbSNP
rs1298451488 2873 dbSNP
rs1446810789 2876 dbSNP
rs1356974925 2887 dbSNP
rs1177560332 2897 dbSNP
rs1240385261 2902 dbSNP
rs1042628165 2903 dbSNP
rs1156765129 2905 dbSNP
rs902779496 2908 dbSNP
rs1408413125 2921 dbSNP
rs1181538288 2923 dbSNP
rs1285820613 2924 dbSNP
rs77491687 2928 dbSNP
rs1239307899 2941 dbSNP
rs568814860 2944 dbSNP
rs1213732068 2945 dbSNP
rs537608679 2946 dbSNP
rs1483179271 2954 dbSNP
rs1180221318 2955 dbSNP
rs1252717391 2956 dbSNP
rs1242937010 2971 dbSNP
rs1440600004 2980 dbSNP
rs1317953155 2985 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 10923.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gugaAUGAAGAAACGUCUACuc 5'
              |||||:||| :| |||  
Target 5' --aaUACUUUUUUUUA-AUGug 3'
 		1 - 19
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 10923.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065670. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gugaAUGAAGAA-----ACGUCUACUc 5'
              |||||:||     ||:: || | 
Target 5' ugaaUACUUUUUUUUAAUGUGCAUUAu 3'
 		6 - 32
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000265073.4 | 3UTR | AAUACUUUUUUUUAAUGUGCAUUAUUAAAAAUAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1065670
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / 4-thiouridine, 3_ML_LG
Location of target site ENST00000265073.4 | 3UTR | UAAGAUGAAUACUUUUUUUUAAUGUGCAUUAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla 0.748 1.6e-3 0.753 1.5e-3 13 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.538 2.8e-3 0.581 1.2e-3 25 Click to see details
GSE14794 Lymphoblastoid cells -0.265 5.8e-3 -0.233 1.4e-2 90 Click to see details
GSE38226 Liver fibrosis 0.49 1.2e-2 0.379 4.5e-2 21 Click to see details
GSE26953 Aortic valvular endothelial cells 0.416 2.2e-2 0.187 1.9e-1 24 Click to see details
GSE32688 Pancreatic cancer 0.236 9.7e-2 0.192 1.5e-1 32 Click to see details
GSE42095 Differentiated embryonic stem cells -0.277 1.0e-1 -0.383 3.6e-2 23 Click to see details
GSE28544 Breast cancer 0.259 1.1e-1 0.232 1.4e-1 24 Click to see details
GSE19350 CNS germ cell tumors 0.25 2.2e-1 0.531 3.8e-2 12 Click to see details
GSE21687 Ependynoma primary tumors -0.092 2.3e-1 -0.095 2.3e-1 64 Click to see details
GSE17306 Multiple myeloma -0.099 2.5e-1 0.435 8.9e-4 49 Click to see details
GSE17498 Multiple myeloma 0.084 3.0e-1 0.128 2.2e-1 40 Click to see details
GSE27834 Pluripotent stem cells 0.05 4.3e-1 -0.038 4.4e-1 16 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.043 4.3e-1 -0.168 2.4e-1 20 Click to see details
GSE21849 B cell lymphoma 0.026 4.5e-1 0.284 6.8e-2 29 Click to see details
GSE21849 B cell lymphoma 0.026 4.5e-1 0.284 6.8e-2 29 Click to see details
GSE21849 B cell lymphoma 0.026 4.5e-1 0.284 6.8e-2 29 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC 0.377 0 0.392 0 49 Click to see details
PAAD -0.976 0.01 -0.800 0.1 4 Click to see details
KICH -0.449 0.01 -0.540 0 24 Click to see details
PRAD -0.299 0.02 -0.289 0.02 48 Click to see details
KIRP 0.335 0.03 0.310 0.04 31 Click to see details
BRCA -0.176 0.06 -0.100 0.19 79 Click to see details
LUSC -0.183 0.14 -0.198 0.12 38 Click to see details
CHOL -0.411 0.14 -0.400 0.14 9 Click to see details
KIRC -0.128 0.15 -0.150 0.12 65 Click to see details
STAD 0.151 0.22 0.089 0.32 29 Click to see details
LUAD 0.25 0.23 0.418 0.1 11 Click to see details
THCA -0.089 0.25 0.059 0.33 59 Click to see details
BLCA 0.135 0.3 0.159 0.27 17 Click to see details
CESC 0.567 0.31 0.500 0.33 3 Click to see details
ESCA 0.164 0.34 0.083 0.42 9 Click to see details
HNSC -0.031 0.42 -0.087 0.29 42 Click to see details
HNSC -0.031 0.42 -0.087 0.29 42 Click to see details
HNSC -0.031 0.42 -0.087 0.29 42 Click to see details
HNSC -0.031 0.42 -0.087 0.29 42 Click to see details
UCEC 0 0.5 -0.088 0.36 19 Click to see details
87 hsa-miR-452-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT150000 MIDN midnolin 2 10
MIRT330600 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT358701 SUB1 SUB1 homolog, transcriptional regulator 2 4
MIRT362854 EIF4H eukaryotic translation initiation factor 4H 2 2
MIRT447215 ATXN7 ataxin 7 2 2
MIRT466655 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D 2 6
MIRT483979 PANK1 pantothenate kinase 1 2 8
MIRT485118 SF3B3 splicing factor 3b subunit 3 2 2
MIRT488864 AUTS8 Autism, susceptibility to, 8 2 2
MIRT492293 SH2B3 SH2B adaptor protein 3 2 2
MIRT492976 NCK2 NCK adaptor protein 2 2 2
MIRT497410 LRRC40 leucine rich repeat containing 40 2 2
MIRT511143 MRPL17 mitochondrial ribosomal protein L17 2 6
MIRT512650 MAP3K2 mitogen-activated protein kinase kinase kinase 2 2 2
MIRT513017 NSFL1C NSFL1 cofactor 2 6
MIRT520445 TSPAN2 tetraspanin 2 2 6
MIRT527995 NDNF neuron derived neurotrophic factor 2 2
MIRT528667 PDE4DIP phosphodiesterase 4D interacting protein 2 2
MIRT533512 TRIM71 tripartite motif containing 71 2 2
MIRT537404 FBXO47 F-box protein 47 2 2
MIRT538161 DCP2 decapping mRNA 2 2 2
MIRT539124 ARHGEF17 Rho guanine nucleotide exchange factor 17 2 2
MIRT540666 MIS18A MIS18 kinetochore protein A 2 4
MIRT542948 GDF11 growth differentiation factor 11 2 2
MIRT547534 MAML3 mastermind like transcriptional coactivator 3 2 2
MIRT559033 C20orf24 chromosome 20 open reading frame 24 2 4
MIRT559554 ARF6 ADP ribosylation factor 6 2 2
MIRT570177 RCBTB1 RCC1 and BTB domain containing protein 1 2 2
MIRT573149 ITGA9 integrin subunit alpha 9 2 2
MIRT575849 Rab1 RAB1A, member RAS oncogene family 1 1
MIRT611034 RRP1B ribosomal RNA processing 1B 2 2
MIRT616281 HMGB1 high mobility group box 1 2 2
MIRT618372 PRKG2 protein kinase, cGMP-dependent, type II 2 2
MIRT619540 PIWIL2 piwi like RNA-mediated gene silencing 2 2 2
MIRT622303 SGIP1 SH3 domain GRB2 like endophilin interacting protein 1 2 2
MIRT622590 PRRG4 proline rich and Gla domain 4 2 2
MIRT624441 CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 2 2
MIRT637089 KLRD1 killer cell lectin like receptor D1 2 2
MIRT639084 ADCYAP1 adenylate cyclase activating polypeptide 1 2 2
MIRT639334 NINJ1 ninjurin 1 2 2
MIRT639798 EIF3E eukaryotic translation initiation factor 3 subunit E 2 2
MIRT640851 RAB3B RAB3B, member RAS oncogene family 2 2
MIRT641628 KIAA1244 ARFGEF family member 3 1 1
MIRT642634 EPPIN epididymal peptidase inhibitor 2 2
MIRT643053 EPPIN-WFDC6 EPPIN-WFDC6 readthrough 2 2
MIRT643416 ERVMER34-1 endogenous retrovirus group MER34 member 1, envelope 2 2
MIRT645586 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT647393 FAM181B family with sequence similarity 181 member B 2 2
MIRT649411 CDC14B cell division cycle 14B 2 2
MIRT649477 CLDN16 claudin 16 2 2
MIRT651307 ZDHHC20 zinc finger DHHC-type containing 20 2 2
MIRT651387 ZBTB16 zinc finger and BTB domain containing 16 2 2
MIRT653411 SLC7A2 solute carrier family 7 member 2 2 2
MIRT654084 RSPH4A radial spoke head 4 homolog A 2 2
MIRT654613 PTPRM protein tyrosine phosphatase, receptor type M 2 2
MIRT655338 PCP4L1 Purkinje cell protein 4 like 1 2 2
MIRT656173 MRPL44 mitochondrial ribosomal protein L44 2 2
MIRT657272 HS3ST3B1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 2 2
MIRT657881 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 2
MIRT659875 CAPRIN1 cell cycle associated protein 1 2 2
MIRT662381 ICA1L islet cell autoantigen 1 like 2 4
MIRT666308 SLC22A3 solute carrier family 22 member 3 2 2
MIRT667274 NAV1 neuron navigator 1 2 2
MIRT667614 LIMCH1 LIM and calponin homology domains 1 2 2
MIRT674242 NUP62 nucleoporin 62 2 4
MIRT690386 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT693402 NUDT16 nudix hydrolase 16 2 2
MIRT702503 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT708632 STMN4 stathmin 4 2 2
MIRT708839 SCAND3 zinc finger BED-type containing 9 1 1
MIRT709016 HSBP1 heat shock factor binding protein 1 2 2
MIRT709235 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT710885 PARL presenilin associated rhomboid like 2 2
MIRT712262 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT712573 ATP2B4 ATPase plasma membrane Ca2+ transporting 4 2 2
MIRT715046 PRPF38A pre-mRNA processing factor 38A 2 2
MIRT718905 GALR1 galanin receptor 1 2 2
MIRT719368 FEM1A fem-1 homolog A 2 2
MIRT719495 SEC24B SEC24 homolog B, COPII coat complex component 2 2
MIRT719601 PRKX protein kinase, X-linked 2 2
MIRT719891 RRP36 ribosomal RNA processing 36 2 2
MIRT720063 ZNF449 zinc finger protein 449 2 2
MIRT721679 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT721724 VTI1A vesicle transport through interaction with t-SNAREs 1A 2 2
MIRT723370 ZNF470 zinc finger protein 470 2 2
MIRT724941 TXNL1 thioredoxin like 1 2 2
MIRT725302 NLRC5 NLR family CARD domain containing 5 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-452 Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
miR-452 Phenethyl isothiocyanate(PEITC) NULL 16741 Microarray neonatal mice liver 20145010 2010 up-regulated
miR-452 Tert-butyl hydroperoxide (t-BHP) NULL 6410 Microarray mouse auditory cells 20510889 2010 down-regulated
miR-452 Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-452 Cisplatin 5460033 NSC119875 approved resistant High Gastric Cancer cell line (BGC823)
hsa-mir-452 Cisplatin 5460033 NSC119875 approved resistant High Ovarian Cancer cell line (A2780CP20)
hsa-mir-452 Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-mir-452 Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)
hsa-mir-452 Cisplatin 5460033 NSC119875 approved resistant cell line (BGC-823)
hsa-miR-452-3p Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-miR-452-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardB)
hsa-miR-452-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-452-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (HCT8)
hsa-miR-452-3p Oxaliplatin 6857599 NSC266046 approved resistant cell line (IGROV-1)
hsa-miR-452-3p Oxaliplatin 6857599 NSC266046 approved resistant cell line (IGROV-1)
hsa-miR-452-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-452-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-452-3p Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-452-3p Ceritinib 57379345 NSC776422 approved sensitive cell line (H3122)

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