miRTarBase - #MIRT359186


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pre-miRNA Information
pre-miRNA hsa-mir-511   
Genomic Coordinates chr10: 17845107 - 17845193
Description Homo sapiens miR-511 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-511-3p
Sequence 54| AAUGUGUAGCAAAAGACAGA |73
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30502461 14 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs548691953 3 dbSNP
rs1322530388 4 dbSNP
rs1313209508 11 dbSNP
rs1223031412 19 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol F2RL1   
Synonyms GPR11, PAR2
Description F2R like trypsin receptor 1
Transcript NM_005242   
Expression
Putative miRNA Targets on F2RL1
3'UTR of F2RL1
(miRNA target sites are highlighted)		 
>F2RL1|NM_005242|3'UTR
   1 GTTTTCCAGGTCCTCAGATGGGAATTGCACAGTAGGATGTGGAACCTGTTTAATGTTATGAGGACGTGTCTGTTATTTCC
  81 TAATCAAAAAGGTCTCACCACATACCATGTGGATGCAGCACCTCTCAGGATTGCTAGGAGCTCCCCTGTTTGCATGAGAA
 161 AAGTAGTCCCCCAAATTAACATCAGTGTCTGTTTCAGAATCTCTCTACTCAGATGACCCCAGAAACTGAACCAACAGAAG
 241 CAGACTTTTCAGAAGATGGTGAAGACAGAAACCCAGTAACTTGCAAAAAGTAGACTTGGTGTGAAGACTCACTTCTCAGC
 321 TGAAATTATATATATACACATATATATATTTTACATCTGGGATCATGATAGACTTGTTAGGGCTTCAAGGCCCTCAGAGA
 401 TGATCAGTCCAACTGAACGACCTTACAAATGAGGAAACCAAGATAAATGAGCTGCCAGAATCAGGTTTCCAATCAACAGC
 481 AGTGAGTTGGGATTGGACAGTAGAATTTCAATGTCCAGTGAGTGAGGTTCTTGTACCACTTCATCAAAATCATGGATCTT
 561 GGCTGGGTGCGGTGCCTCATGCCTGTAATCCTAGCACTTTGGGAGGCTGAGGCAGGCAATCACTTGAGGTCAGGAGTTCG
 641 AGACCAGCCTGGCCATCATGGCGAAACCTCATCTCTACTAAAAATACAAAAGTTAACCAGGTGTGTGGTGCACGTTTGTA
 721 ATCCCAGTTACTCAGGAGGCTGAGGCACAAGAATTGAGTATCACTTTAACTCAGGAGGCAGAGGTTGCAGTGAGCCGAGA
 801 TTGCACCACTGCACTCCAGCTTGGGTGATAAAATAAAATAAAATAGTCGTGAATCTTGTTCAAAATGCAGATTCCTCAGA
 881 TTCAATAATGAGAGCTCAGACTGGGAACAGGGCCCAGGAATCTGTGTGGTACAAACCTGCATGGTGTTTATGCACACAGA
 961 GATTTGAGAACCATTGTTCTGAATGCTGCTTCCATTTGACAAAGTGCCGTGATAATTTTTGAAAAGAGAAGCAAACAATG
1041 GTGTCTCTTTTATGTTCAGCTTATAATGAAATCTGTTTGTTGACTTATTAGGACTTTGAATTATTTCTTTATTAACCCTC
1121 TGAGTTTTTGTATGTATTATTATTAAAGAAAAATGCAATCAGGATTTTAAACATGTAAATACAAATTTTGTATAACTTTT
1201 GATGACTTCAGTGAAATTTTCAGGTAGTCTGAGTAATAGATTGTTTTGCCACTTAGAATAGCATTTGCCACTTAGTATTT
1281 TAAAAAATAATTGTTGGAGTATTTATTGTCAGTTTTGTTCACTTGTTATCTAATACAAAATTATAAAGCCTTCAGAGGGT
1361 TTGGACCACATCTCTTTGGAAAATAGTTTGCAACATATTTAAGAGATACTTGATGCCAAAATGACTTTATACAACGATTG
1441 TATTTGTGACTTTTAAAAATAATTATTTTATTGTGTAATTGATTTATAAATAACAAAATTTTTTTTACAACTTAAAAAAA
1521 AAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agacagaaaacgAUGUGUAa 5'
                      ||||||| 
Target 5' aaattatatataTACACATa 3'
 323 - 342 140.00 -5.50
2 
miRNA  3' agacagaAAACGAUGUGUAa 5'
                 | || |:|||:| 
Target 5' ccaggtgTGTGGTGCACGTt 3'
 697 - 716 117.00 -10.30
3 
miRNA  3' agacagaAAACGAUGUGUAa 5'
                 ||||| |||:|| 
Target 5' aaaatagTTTGCAACATATt 3'
 1380 - 1399 117.00 -9.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30187069 18 COSMIC
COSN30483813 22 COSMIC
COSN26975566 64 COSMIC
COSN31612334 67 COSMIC
COSN15661506 108 COSMIC
COSN30490014 112 COSMIC
COSN30447797 134 COSMIC
COSN30455894 146 COSMIC
COSN20101399 350 COSMIC
COSN4851948 571 COSMIC
COSN5865663 627 COSMIC
COSN21348450 1046 COSMIC
COSN26778711 1181 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs748792492 1 dbSNP
rs769180337 3 dbSNP
rs779342435 7 dbSNP
rs748538129 9 dbSNP
rs772427569 13 dbSNP
rs1467542489 17 dbSNP
rs1201401419 18 dbSNP
rs1163345760 19 dbSNP
rs2243084 22 dbSNP
rs187721390 23 dbSNP
rs1325689223 25 dbSNP
rs770958350 26 dbSNP
rs376212863 28 dbSNP
rs189860773 29 dbSNP
rs2243063 30 dbSNP
rs751458316 31 dbSNP
rs569299379 35 dbSNP
rs1356965647 40 dbSNP
rs1324114225 49 dbSNP
rs1025820977 50 dbSNP
rs529274010 56 dbSNP
rs888624547 66 dbSNP
rs146054906 67 dbSNP
rs2243064 79 dbSNP
rs1392765651 86 dbSNP
rs1403268887 87 dbSNP
rs1278650964 102 dbSNP
rs1335416870 104 dbSNP
rs535427440 109 dbSNP
rs143647822 113 dbSNP
rs1469761219 123 dbSNP
rs1407431458 130 dbSNP
rs565779111 137 dbSNP
rs534668337 146 dbSNP
rs930211294 149 dbSNP
rs557576114 154 dbSNP
rs1185286469 162 dbSNP
rs1048656653 168 dbSNP
rs1241375081 174 dbSNP
rs1242348885 177 dbSNP
rs2243065 181 dbSNP
rs1461800831 186 dbSNP
rs1280712472 191 dbSNP
rs1349766524 192 dbSNP
rs909859666 192 dbSNP
rs1279847589 200 dbSNP
rs942724956 219 dbSNP
rs1380055575 223 dbSNP
rs1313781570 224 dbSNP
rs1039726263 233 dbSNP
rs1382410546 235 dbSNP
rs976859023 236 dbSNP
rs1399462048 242 dbSNP
rs376383495 245 dbSNP
rs1202049453 249 dbSNP
rs1029702061 278 dbSNP
rs998312382 304 dbSNP
rs1159452397 329 dbSNP
rs1421780292 330 dbSNP
rs1158094601 333 dbSNP
rs1183201032 334 dbSNP
rs62365147 336 dbSNP
rs1445375959 338 dbSNP
rs35226539 340 dbSNP
rs62365148 340 dbSNP
rs70982645 340 dbSNP
rs1246246746 341 dbSNP
rs35323826 341 dbSNP
rs566827130 345 dbSNP
rs1267831781 346 dbSNP
rs1429256086 348 dbSNP
rs891648582 349 dbSNP
rs1299310083 354 dbSNP
rs1402296875 358 dbSNP
rs759769643 368 dbSNP
rs1163253974 392 dbSNP
rs1425460204 393 dbSNP
rs771309279 403 dbSNP
rs772459618 405 dbSNP
rs956657538 412 dbSNP
rs2243085 414 dbSNP
rs537268108 419 dbSNP
rs1398692453 429 dbSNP
rs3135469 434 dbSNP
rs979029135 440 dbSNP
rs1311843682 444 dbSNP
rs1222780977 445 dbSNP
rs1323092005 449 dbSNP
rs927128692 452 dbSNP
rs992616359 463 dbSNP
rs918738342 466 dbSNP
rs1339445956 473 dbSNP
rs1279447656 478 dbSNP
rs951563898 485 dbSNP
rs1237829366 486 dbSNP
rs2243066 488 dbSNP
rs542600555 489 dbSNP
rs895496150 496 dbSNP
rs1351792319 497 dbSNP
rs929607551 498 dbSNP
rs1047320673 499 dbSNP
rs559366027 504 dbSNP
rs775502372 512 dbSNP
rs942672585 537 dbSNP
rs1172815595 546 dbSNP
rs1201751986 549 dbSNP
rs1040100177 553 dbSNP
rs1199821375 567 dbSNP
rs2243067 571 dbSNP
rs1458109874 572 dbSNP
rs1040300970 576 dbSNP
rs764212952 577 dbSNP
rs934049431 580 dbSNP
rs571965986 585 dbSNP
rs1052557999 586 dbSNP
rs1221017626 598 dbSNP
rs1321970485 599 dbSNP
rs1200325767 601 dbSNP
rs2243068 601 dbSNP
rs1220214976 619 dbSNP
rs182575884 624 dbSNP
rs1278062597 625 dbSNP
rs891593517 630 dbSNP
rs1436325746 636 dbSNP
rs1010090920 638 dbSNP
rs1181324459 641 dbSNP
rs1378332347 653 dbSNP
rs565259436 659 dbSNP
rs899989792 660 dbSNP
rs1001491553 661 dbSNP
rs998278137 663 dbSNP
rs1429215197 668 dbSNP
rs1470275539 669 dbSNP
rs1034412228 675 dbSNP
rs764267533 678 dbSNP
rs1460458277 681 dbSNP
rs1263117814 688 dbSNP
rs1314378022 693 dbSNP
rs149930351 702 dbSNP
rs2243069 712 dbSNP
rs145017560 714 dbSNP
rs1377868883 715 dbSNP
rs371907637 716 dbSNP
rs1323790249 720 dbSNP
rs984263874 728 dbSNP
rs1467457829 730 dbSNP
rs910084839 730 dbSNP
rs1343225255 766 dbSNP
rs532226442 771 dbSNP
rs866320882 776 dbSNP
rs1221156469 781 dbSNP
rs1282028928 784 dbSNP
rs922579399 785 dbSNP
rs375089406 790 dbSNP
rs927155811 791 dbSNP
rs988606937 798 dbSNP
rs1249445928 803 dbSNP
rs368806393 805 dbSNP
rs1215474356 823 dbSNP
rs778005769 828 dbSNP
rs945828420 828 dbSNP
rs1268314066 836 dbSNP
rs1244048845 845 dbSNP
rs868602923 849 dbSNP
rs904381184 850 dbSNP
rs779766822 868 dbSNP
rs916973673 869 dbSNP
rs937243315 876 dbSNP
rs1055729608 877 dbSNP
rs895449892 880 dbSNP
rs1268221012 893 dbSNP
rs1400435829 894 dbSNP
rs1013926448 895 dbSNP
rs1161356728 897 dbSNP
rs1025784550 899 dbSNP
rs1478457185 902 dbSNP
rs36066481 913 dbSNP
rs201009228 916 dbSNP
rs369526981 916 dbSNP
rs757355827 923 dbSNP
rs1426111266 925 dbSNP
rs1260314708 928 dbSNP
rs35274750 940 dbSNP
rs1193550674 942 dbSNP
rs1005296192 952 dbSNP
rs753529875 958 dbSNP
rs929658241 1005 dbSNP
rs1220549215 1007 dbSNP
rs2243070 1009 dbSNP
rs909532964 1010 dbSNP
rs2243071 1013 dbSNP
rs537632941 1014 dbSNP
rs1305814576 1022 dbSNP
rs549342443 1022 dbSNP
rs1219166207 1027 dbSNP
rs753853855 1029 dbSNP
rs1342149701 1039 dbSNP
rs955516364 1042 dbSNP
rs760446634 1054 dbSNP
rs1390959666 1055 dbSNP
rs534549684 1074 dbSNP
rs900000981 1076 dbSNP
rs1460071379 1077 dbSNP
rs1401821395 1084 dbSNP
rs998330727 1094 dbSNP
rs1371988860 1098 dbSNP
rs1170595866 1108 dbSNP
rs1051191508 1117 dbSNP
rs1426256619 1118 dbSNP
rs1451361365 1121 dbSNP
rs892581528 1121 dbSNP
rs1009635373 1122 dbSNP
rs534930455 1125 dbSNP
rs1479738081 1129 dbSNP
rs979540907 1131 dbSNP
rs1199209431 1132 dbSNP
rs1281182170 1135 dbSNP
rs1319851292 1135 dbSNP
rs762023152 1141 dbSNP
rs766193566 1142 dbSNP
rs1245253398 1148 dbSNP
rs146194119 1156 dbSNP
rs376364152 1157 dbSNP
rs1034233222 1159 dbSNP
rs1395157914 1164 dbSNP
rs937209932 1165 dbSNP
rs1056079982 1174 dbSNP
rs1291193608 1182 dbSNP
rs1477937747 1185 dbSNP
rs1378569499 1196 dbSNP
rs754913009 1205 dbSNP
rs1046709569 1211 dbSNP
rs958553196 1214 dbSNP
rs886797068 1230 dbSNP
rs1188866271 1232 dbSNP
rs1199307352 1240 dbSNP
rs1459125085 1244 dbSNP
rs567614928 1248 dbSNP
rs1260264119 1250 dbSNP
rs1005244021 1251 dbSNP
rs1428377999 1264 dbSNP
rs147763831 1271 dbSNP
rs899974780 1289 dbSNP
rs997026403 1290 dbSNP
rs1448414484 1293 dbSNP
rs1422409585 1298 dbSNP
rs1335397815 1300 dbSNP
rs113368839 1318 dbSNP
rs1360673679 1323 dbSNP
rs1174627994 1326 dbSNP
rs1451937601 1327 dbSNP
rs1379965721 1334 dbSNP
rs955642682 1346 dbSNP
rs951158657 1349 dbSNP
rs1420984860 1350 dbSNP
rs988822660 1354 dbSNP
rs982550989 1375 dbSNP
rs968054502 1386 dbSNP
rs909545379 1393 dbSNP
rs1203201615 1402 dbSNP
rs940996240 1423 dbSNP
rs1361210120 1428 dbSNP
rs1396492373 1430 dbSNP
rs1040378343 1436 dbSNP
rs926698396 1437 dbSNP
rs573164812 1439 dbSNP
rs1244126563 1441 dbSNP
rs545102761 1443 dbSNP
rs1051287508 1446 dbSNP
rs1360279711 1447 dbSNP
rs1159551831 1451 dbSNP
rs1421685847 1457 dbSNP
rs892634309 1460 dbSNP
rs945478904 1473 dbSNP
rs558997126 1480 dbSNP
rs752294684 1483 dbSNP
rs1002188816 1487 dbSNP
rs1034693299 1495 dbSNP
rs1263548400 1495 dbSNP
rs941047990 1498 dbSNP
rs1288565313 1499 dbSNP
rs575690460 1499 dbSNP
rs1201501093 1503 dbSNP
rs143476361 1508 dbSNP
rs1357828261 1509 dbSNP
rs1286529323 1514 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agacagaaaacgAUGUGUAa 5'
                      ||||||| 
Target 5' -aauuauauauaUACACAUa 3'
 		1 - 19
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293
Disease 2150.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "HITS-CLIP data was present in GSM714642. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agacagaaaacgAUGUGUAa 5'
                      ||||||| 
Target 5' ----uauauauaUACACAUa 3'
 		1 - 16
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 2150.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065669. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM714642
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000296677.4 | 3UTR | UAUAUAUAUACACAUAUAUAUAUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000296677.4 | 3UTR | AAUUAUAUAUAUACACAUAUAUAUAUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1065669
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_8
Location of target site ENST00000296677.4 | 3UTR | UUAUAUAUAUACACAUAUAUAUAUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
239 hsa-miR-511-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT068303 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT072025 SCP2 sterol carrier protein 2 2 2
MIRT073626 IGF1R insulin like growth factor 1 receptor 2 2
MIRT080574 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 8
MIRT094167 PCGF3 polycomb group ring finger 3 2 4
MIRT096536 LIFR LIF receptor alpha 2 2
MIRT156224 SLC25A12 solute carrier family 25 member 12 2 2
MIRT177714 ADO 2-aminoethanethiol dioxygenase 2 2
MIRT184922 ZNF268 zinc finger protein 268 2 2
MIRT185107 LYPLAL1 lysophospholipase like 1 2 2
MIRT193093 MAPK6 mitogen-activated protein kinase 6 2 2
MIRT213346 TADA2B transcriptional adaptor 2B 2 2
MIRT225350 SDCBP syndecan binding protein 2 2
MIRT226972 AKAP2 A-kinase anchoring protein 2 2 6
MIRT226977 PALM2-AKAP2 PALM2-AKAP2 readthrough 2 6
MIRT229844 YIPF6 Yip1 domain family member 6 2 2
MIRT230994 PRRG4 proline rich and Gla domain 4 2 2
MIRT270215 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 2 4
MIRT277060 NDFIP2 Nedd4 family interacting protein 2 2 4
MIRT278336 CFL2 cofilin 2 2 4
MIRT280390 CALM1 calmodulin 1 2 2
MIRT298042 BACH1 BTB domain and CNC homolog 1 2 2
MIRT302449 CLIP4 CAP-Gly domain containing linker protein family member 4 2 2
MIRT311937 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2 4
MIRT329263 AIMP1 aminoacyl tRNA synthetase complex interacting multifunctional protein 1 2 2
MIRT359186 F2RL1 F2R like trypsin receptor 1 2 6
MIRT363208 YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta 2 2
MIRT371124 YTHDC1 YTH domain containing 1 2 2
MIRT386755 TAOK1 TAO kinase 1 2 2
MIRT395122 BAHD1 bromo adjacent homology domain containing 1 2 2
MIRT396089 MKLN1 muskelin 1 2 2
MIRT443566 EVX2 even-skipped homeobox 2 2 2
MIRT447626 CUL3 cullin 3 2 2
MIRT447680 ZNF264 zinc finger protein 264 2 2
MIRT451053 NT5C1B 5'-nucleotidase, cytosolic IB 2 2
MIRT452048 NT5C1B-RDH14 NT5C1B-RDH14 readthrough 2 2
MIRT459890 KIAA1191 KIAA1191 2 4
MIRT464483 UGCG UDP-glucose ceramide glucosyltransferase 2 2
MIRT465264 TRIM44 tripartite motif containing 44 2 2
MIRT467570 SLITRK4 SLIT and NTRK like family member 4 2 2
MIRT467800 SLC2A14 solute carrier family 2 member 14 2 2
MIRT469543 RASAL2 RAS protein activator like 2 2 2
MIRT469931 PTPRJ protein tyrosine phosphatase, receptor type J 2 4
MIRT474056 LMNB2 lamin B2 2 2
MIRT474097 LMBR1L limb development membrane protein 1 like 2 2
MIRT475183 INSIG2 insulin induced gene 2 2 6
MIRT484264 FAM177A1 family with sequence similarity 177 member A1 2 2
MIRT487567 LOXL2 lysyl oxidase like 2 2 2
MIRT499080 CBWD1 COBW domain containing 1 2 6
MIRT499126 CBWD5 COBW domain containing 5 2 6
MIRT502093 KPNA5 karyopherin subunit alpha 5 2 8
MIRT503328 SOX5 SRY-box 5 2 6
MIRT503839 NCAM2 neural cell adhesion molecule 2 2 6
MIRT504030 CEP104 centrosomal protein 104 2 4
MIRT504314 LHFPL5 LHFPL tetraspan subfamily member 5 2 8
MIRT504525 BVES blood vessel epicardial substance 2 6
MIRT504680 CYGB cytoglobin 2 4
MIRT504815 DOCK7 dedicator of cytokinesis 7 2 4
MIRT505757 SENP1 SUMO1/sentrin specific peptidase 1 2 8
MIRT506151 PLEKHA3 pleckstrin homology domain containing A3 2 6
MIRT506908 KCNJ3 potassium voltage-gated channel subfamily J member 3 2 6
MIRT508259 CD226 CD226 molecule 2 2
MIRT508307 XRCC3 X-ray repair cross complementing 3 2 4
MIRT508784 CDKL1 cyclin dependent kinase like 1 2 6
MIRT508897 C4orf29 abhydrolase domain containing 18 2 6
MIRT508967 TECRL trans-2,3-enoyl-CoA reductase like 2 4
MIRT508973 MLLT3 MLLT3, super elongation complex subunit 2 6
MIRT509149 TSC22D3 TSC22 domain family member 3 2 4
MIRT509188 TSPAN2 tetraspanin 2 2 4
MIRT509212 BRCC3 BRCA1/BRCA2-containing complex subunit 3 2 4
MIRT509214 SEC23IP SEC23 interacting protein 2 6
MIRT509237 PDE10A phosphodiesterase 10A 2 6
MIRT509248 OTX1 orthodenticle homeobox 1 2 6
MIRT509469 TRIM2 tripartite motif containing 2 2 4
MIRT509754 EFCAB11 EF-hand calcium binding domain 11 2 4
MIRT509805 CHAF1B chromatin assembly factor 1 subunit B 2 4
MIRT509938 USP25 ubiquitin specific peptidase 25 2 4
MIRT509954 ITGA1 integrin subunit alpha 1 2 6
MIRT509965 KANSL1L KAT8 regulatory NSL complex subunit 1 like 2 4
MIRT509988 GTF2H1 general transcription factor IIH subunit 1 2 4
MIRT510036 NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 2 6
MIRT510164 STARD8 StAR related lipid transfer domain containing 8 2 4
MIRT510199 CYP4F11 cytochrome P450 family 4 subfamily F member 11 2 9
MIRT510249 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 6
MIRT510502 YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta 2 2
MIRT510906 PURA purine rich element binding protein A 2 4
MIRT511051 NRF1 nuclear respiratory factor 1 2 4
MIRT511273 KLHL23 kelch like family member 23 2 4
MIRT511368 IL6ST interleukin 6 signal transducer 2 4
MIRT511521 HMGB2 high mobility group box 2 2 4
MIRT512004 DUSP7 dual specificity phosphatase 7 2 4
MIRT512080 CSRNP3 cysteine and serine rich nuclear protein 3 2 8
MIRT514234 EPOR erythropoietin receptor 2 4
MIRT515327 SLC35E3 solute carrier family 35 member E3 2 4
MIRT515409 WDR72 WD repeat domain 72 2 8
MIRT515973 C9orf156 tRNA methyltransferase O 2 4
MIRT516015 NLGN3 neuroligin 3 2 4
MIRT516271 DBT dihydrolipoamide branched chain transacylase E2 2 10
MIRT516495 GLRX2 glutaredoxin 2 2 4
MIRT517272 ANG angiogenin 2 4
MIRT517511 KCNK12 potassium two pore domain channel subfamily K member 12 2 4
MIRT517555 VENTX VENT homeobox 2 4
MIRT519511 RBM22 RNA binding motif protein 22 2 4
MIRT520350 UBN2 ubinuclein 2 2 2
MIRT520687 TMED7 transmembrane p24 trafficking protein 7 2 4
MIRT520960 SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 2 2
MIRT521759 PPIL1 peptidylprolyl isomerase like 1 2 6
MIRT522036 PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 2 4
MIRT522127 NELL2 neural EGFL like 2 2 4
MIRT522624 MAP7D1 MAP7 domain containing 1 2 4
MIRT522761 LDLR low density lipoprotein receptor 2 6
MIRT522924 KAT6A lysine acetyltransferase 6A 2 6
MIRT523391 GRIN2B glutamate ionotropic receptor NMDA type subunit 2B 2 4
MIRT523851 ETV6 ETS variant 6 2 2
MIRT523890 EPHA5 EPH receptor A5 2 4
MIRT523945 E2F8 E2F transcription factor 8 2 4
MIRT524222 DCUN1D3 defective in cullin neddylation 1 domain containing 3 2 2
MIRT524410 CNTNAP5 contactin associated protein like 5 2 4
MIRT524568 CALML4 calmodulin like 4 2 4
MIRT524611 ENTHD1 ENTH domain containing 1 2 2
MIRT524907 AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 2 4
MIRT525019 ABHD13 abhydrolase domain containing 13 2 6
MIRT525211 C19orf12 chromosome 19 open reading frame 12 2 2
MIRT528253 BMS1 BMS1, ribosome biogenesis factor 2 2
MIRT528294 ZNF76 zinc finger protein 76 2 2
MIRT531898 INVS inversin 2 4
MIRT535962 MOGAT1 monoacylglycerol O-acyltransferase 1 2 2
MIRT540823 SSPN sarcospan 2 4
MIRT541836 CDON cell adhesion associated, oncogene regulated 2 4
MIRT541914 BMPR1A bone morphogenetic protein receptor type 1A 2 4
MIRT542156 KIAA2018 upstream transcription factor family member 3 2 6
MIRT542175 SERTM1 serine rich and transmembrane domain containing 1 2 6
MIRT542217 IRS1 insulin receptor substrate 1 2 4
MIRT542225 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 6
MIRT543654 PLEKHM3 pleckstrin homology domain containing M3 2 2
MIRT544097 EDA2R ectodysplasin A2 receptor 2 2
MIRT544533 SPPL3 signal peptide peptidase like 3 2 2
MIRT544954 TUB tubby bipartite transcription factor 2 4
MIRT545027 PLP1 proteolipid protein 1 2 2
MIRT546524 SERTAD3 SERTA domain containing 3 2 2
MIRT547242 OSBPL9 oxysterol binding protein like 9 2 4
MIRT548198 FNIP1 folliculin interacting protein 1 2 2
MIRT548272 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT549480 ACBD5 acyl-CoA binding domain containing 5 2 2
MIRT549498 ABI2 abl interactor 2 2 2
MIRT550325 SMAD9 SMAD family member 9 2 2
MIRT550563 CYP4V2 cytochrome P450 family 4 subfamily V member 2 2 6
MIRT550642 AR androgen receptor 2 2
MIRT550945 CTSE cathepsin E 2 4
MIRT550961 POT1 protection of telomeres 1 2 2
MIRT551178 ATP7A ATPase copper transporting alpha 2 2
MIRT551416 LRRC31 leucine rich repeat containing 31 2 2
MIRT551507 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2 2
MIRT551517 MMADHC methylmalonic aciduria and homocystinuria, cblD type 2 2
MIRT551550 TMEM133 transmembrane protein 133 2 2
MIRT551757 TRIM42 tripartite motif containing 42 2 2
MIRT551872 TMEM47 transmembrane protein 47 2 2
MIRT551882 EPHA1 EPH receptor A1 2 2
MIRT551917 IGLON5 IgLON family member 5 2 2
MIRT552377 ZNF562 zinc finger protein 562 2 2
MIRT552543 ZHX3 zinc fingers and homeoboxes 3 2 2
MIRT553419 TRAF5 TNF receptor associated factor 5 2 2
MIRT554080 SNX4 sorting nexin 4 2 4
MIRT554588 RRAGC Ras related GTP binding C 2 2
MIRT554887 RCC2 regulator of chromosome condensation 2 2 2
MIRT555568 PLCB1 phospholipase C beta 1 2 2
MIRT555819 PCDH11Y protocadherin 11 Y-linked 2 4
MIRT555969 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT556028 MXD1 MAX dimerization protein 1 2 2
MIRT556206 MBNL2 muscleblind like splicing regulator 2 2 2
MIRT556251 MARCH3 membrane associated ring-CH-type finger 3 2 2
MIRT557265 HMGN3 high mobility group nucleosomal binding domain 3 2 2
MIRT557334 HHIP hedgehog interacting protein 2 2
MIRT557427 GXYLT2 glucoside xylosyltransferase 2 2 4
MIRT557537 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT557797 FREM2 FRAS1 related extracellular matrix protein 2 2 2
MIRT557805 FOXP1 forkhead box P1 2 2
MIRT558569 CRIM1 cysteine rich transmembrane BMP regulator 1 2 2
MIRT558734 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT558878 CCSER2 coiled-coil serine rich protein 2 2 2
MIRT558933 CBX1 chromobox 1 2 2
MIRT559133 BTG3 BTG anti-proliferation factor 3 2 4
MIRT559168 BRWD3 bromodomain and WD repeat domain containing 3 2 4
MIRT559618 AMER1 APC membrane recruitment protein 1 2 2
MIRT561627 SERBP1 SERPINE1 mRNA binding protein 1 2 2
MIRT561971 LRRC59 leucine rich repeat containing 59 2 2
MIRT563049 ZNF138 zinc finger protein 138 2 2
MIRT563432 TRIM13 tripartite motif containing 13 2 4
MIRT563540 RBM41 RNA binding motif protein 41 2 2
MIRT564647 ZNF544 zinc finger protein 544 2 2
MIRT567674 EIF5 eukaryotic translation initiation factor 5 2 2
MIRT567755 DLC1 DLC1 Rho GTPase activating protein 2 2
MIRT568267 BICD2 BICD cargo adaptor 2 2 2
MIRT569160 SIGMAR1 sigma non-opioid intracellular receptor 1 2 2
MIRT569179 DMD dystrophin 2 2
MIRT569427 DCAF8 DDB1 and CUL4 associated factor 8 2 2
MIRT569853 RGS5 regulator of G protein signaling 5 2 2
MIRT570554 PLAG1 PLAG1 zinc finger 2 2
MIRT571233 SYT9 synaptotagmin 9 2 2
MIRT572276 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT572539 ZFHX2 zinc finger homeobox 2 2 2
MIRT574271 ZNF350 zinc finger protein 350 2 2
MIRT574428 SMC1A structural maintenance of chromosomes 1A 2 2
MIRT574671 HNRNPDL heterogeneous nuclear ribonucleoprotein D like 2 2
MIRT576699 Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 2 2
MIRT607889 SATB1 SATB homeobox 1 2 2
MIRT608846 FGF14 fibroblast growth factor 14 2 6
MIRT608854 SPATA6 spermatogenesis associated 6 2 2
MIRT608879 CNTF ciliary neurotrophic factor 2 6
MIRT608899 ZNF860 zinc finger protein 860 2 2
MIRT608948 C12orf60 chromosome 12 open reading frame 60 2 2
MIRT609029 CDH6 cadherin 6 2 2
MIRT609063 LPP LIM domain containing preferred translocation partner in lipoma 2 4
MIRT612277 ZNF280B zinc finger protein 280B 2 2
MIRT612520 SEPT7 septin 7 2 2
MIRT617202 GREM1 gremlin 1, DAN family BMP antagonist 2 2
MIRT618700 KIF13A kinesin family member 13A 2 2
MIRT619141 AFF2 AF4/FMR2 family member 2 2 2
MIRT621071 RAB11FIP3 RAB11 family interacting protein 3 2 6
MIRT627811 PTCHD1 patched domain containing 1 2 4
MIRT641782 ZBTB20 zinc finger and BTB domain containing 20 2 2
MIRT657645 GPRC5A G protein-coupled receptor class C group 5 member A 2 2
MIRT669313 C16orf72 chromosome 16 open reading frame 72 2 2
MIRT674602 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 2
MIRT684064 CPPED1 calcineurin like phosphoesterase domain containing 1 2 2
MIRT685149 TACR3 tachykinin receptor 3 2 2
MIRT693446 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 2 2
MIRT693808 WDR3 WD repeat domain 3 2 2
MIRT703845 ETV3 ETS variant 3 2 2
MIRT707100 ZNF850 zinc finger protein 850 2 2
MIRT707375 SVIP small VCP interacting protein 2 2
MIRT707467 ROCK2 Rho associated coiled-coil containing protein kinase 2 2 2
MIRT707514 PPP1R16B protein phosphatase 1 regulatory subunit 16B 2 2
MIRT707542 ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 2 2
MIRT707560 CLVS2 clavesin 2 2 2
MIRT708113 HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2 2
MIRT708217 ADD2 adducin 2 2 2
MIRT710678 MX2 MX dynamin like GTPase 2 2 2
MIRT755898 ZFPM2-AS1 ZFPM2 antisense RNA 1 3 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-511-3p Doxorubicin 31703 NSC123127 approved resistant High Anaplastic Thyroid Cancer tissue
hsa-miR-511-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)

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