miRTarBase - #MIRT370127


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pre-miRNA Information
pre-miRNA hsa-mir-5703   
Genomic Coordinates chr2: 227472132 - 227472187
Description Homo sapiens miR-5703 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-5703
Sequence 31| AGGAGAAGUCGGGAAGGU |48
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1183679532 2 dbSNP
rs932217747 3 dbSNP
rs1209011098 5 dbSNP
rs1486736741 8 dbSNP
rs1051940023 9 dbSNP
rs1223246998 10 dbSNP
rs1232901648 11 dbSNP
rs1424402647 12 dbSNP
rs890720113 15 dbSNP
rs1350946664 17 dbSNP
rs1292388472 18 dbSNP
rs1399653485 18 dbSNP
rs752410442 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TRIB3   
Synonyms C20orf97, NIPK, SINK, SKIP3, TRB3
Description tribbles pseudokinase 3
Transcript NM_021158   
Expression
Putative miRNA Targets on TRIB3
3'UTR of TRIB3
(miRNA target sites are highlighted)		 
>TRIB3|NM_021158|3'UTR
   1 GACCACCCTACTACACGCTCAGCTGCCAACAGTGGATTGAGTTTGGGGGTAGCTCCAAGCCTTCTCCTGCCTCTGAACTG
  81 AGCCAAACCTTCAGTGCCTTCCAGAAGGGAGAAAGGCAGAAGCCTGTGTGGAGTGTGCTGTGTACACATCTGCTTTGTTC
 161 CACACACATGCAGTTCCTGCTTGGGTGCTTATCAGGTGCCAAGCCCTGTTCTCGGTGCTGGGAGTACAGCAGTGAGCAAA
 241 GGAGACAATATTCCCTGCTCACAGAGATGACAAACTGGCATCCTTGAGCTGACAACACTTTTCCATGACCATAGGTCACT
 321 GTCTACACTGGGTACACTTTGTACCAGTGTCGGCCTCCACTGATGCTGGTGCTCAGGCACCTCTGTCCAAGGACAATCCC
 401 TTTCACAAACAAACCAGCTGCCTTTGTATCTTGTACCTTTTCAGAGAAAGGGAGGTATCCCTGTGCCAAAGGCTCCAGGC
 481 CTCTCCCCTGCAACTCAGGACCCAAGCCCAGCTCACTCTGGGAACTGTGTTCCCAGCATCTCTGTCCTCTTGATTAAGAG
 561 ATTCTCCTTCCAGGCCTAAGCCTGGGATTTGGGCCAGAGATAAGAATCCAAACTATGAGGCTAGTTCTTGTCTAACTCAA
 641 GACTGTTCTGGAATGAGGGTCCAGGCCTGTCAACCATGGGGCTTCTGACCTGAGCACCAAGGTTGAGGGACAGGATTAGG
 721 CAGGGTCTGTCCTGTGGCCACCTGGAAAGTCCCAGGTGGGACTCTTCTGGGGACACTTGGGGTCCACAATCCCAGGTCCA
 801 TACTCTAGGTTTTGGATACCATGAGTATGTATGTTTACCTGTGCCTAATAAAGGAGAATTATGAAATAAAAAAAAAAAAA
 881 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugGAAGGGCUGAAGAGGa 5'
            || |  | ||||||| 
Target 5' agCTCCAAGCCTTCTCCt 3'
 51 - 68 148.00 -14.40
2 
miRNA  3' uggaagggcUGAAGAGGa 5'
                   ||||:||| 
Target 5' gctgacaacACTTTTCCa 3'
 288 - 305 129.00 -9.80
3 
miRNA  3' uggaAGGGCUGAAGAGGa 5'
              ||| |:| ||||| 
Target 5' aggcTCCAGGCCTCTCCc 3'
 470 - 487 126.00 -12.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM316128 1 COSMIC
COSN31521652 42 COSMIC
COSN30489792 57 COSMIC
COSN30501150 60 COSMIC
COSN30463704 90 COSMIC
COSN30147612 103 COSMIC
COSN19566766 205 COSMIC
COSN29354843 232 COSMIC
COSN10015369 247 COSMIC
COSN31961813 351 COSMIC
COSN31543297 464 COSMIC
COSN31482446 482 COSMIC
COSN30176944 550 COSMIC
COSN30177003 565 COSMIC
COSN31483422 595 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs771396793 8 dbSNP
rs776834364 12 dbSNP
rs759977026 16 dbSNP
rs759890273 17 dbSNP
rs765507830 18 dbSNP
rs1235908511 22 dbSNP
rs763062412 23 dbSNP
rs767371142 24 dbSNP
rs1357048045 26 dbSNP
rs1426151485 31 dbSNP
rs1477047761 33 dbSNP
rs780019539 38 dbSNP
rs1441997088 42 dbSNP
rs188020529 44 dbSNP
rs778272871 45 dbSNP
rs755972826 46 dbSNP
rs966171299 47 dbSNP
rs1466160557 49 dbSNP
rs766246372 53 dbSNP
rs900423317 61 dbSNP
rs556568862 62 dbSNP
rs1476305025 65 dbSNP
rs758744536 67 dbSNP
rs1321435934 75 dbSNP
rs6084315 90 dbSNP
rs977525080 91 dbSNP
rs996823999 95 dbSNP
rs1231058058 97 dbSNP
rs6051679 99 dbSNP
rs1028264674 102 dbSNP
rs952685720 110 dbSNP
rs1206557469 113 dbSNP
rs1442908833 127 dbSNP
rs780202035 130 dbSNP
rs936023029 132 dbSNP
rs1469360373 135 dbSNP
rs1182377595 136 dbSNP
rs1015638039 146 dbSNP
rs1467739910 161 dbSNP
rs192061190 172 dbSNP
rs1313039413 174 dbSNP
rs948610596 193 dbSNP
rs1045582422 194 dbSNP
rs535985314 195 dbSNP
rs939852649 196 dbSNP
rs928229395 204 dbSNP
rs1036774981 212 dbSNP
rs4352283 214 dbSNP
rs755089348 215 dbSNP
rs914930779 221 dbSNP
rs1418233844 229 dbSNP
rs1405530229 235 dbSNP
rs1410684385 249 dbSNP
rs1180350883 250 dbSNP
rs1290400509 253 dbSNP
rs1440223904 255 dbSNP
rs1343742711 257 dbSNP
rs1027911133 260 dbSNP
rs1211242068 262 dbSNP
rs868518762 264 dbSNP
rs889386390 272 dbSNP
rs6051682 284 dbSNP
rs1008198331 300 dbSNP
rs946328515 302 dbSNP
rs1345715311 316 dbSNP
rs1042540949 322 dbSNP
rs1202094739 324 dbSNP
rs923704772 329 dbSNP
rs944575156 336 dbSNP
rs142330335 339 dbSNP
rs1205467846 342 dbSNP
rs376258139 352 dbSNP
rs1370872943 353 dbSNP
rs544146672 360 dbSNP
rs527432999 361 dbSNP
rs558443192 366 dbSNP
rs748128309 369 dbSNP
rs769881992 370 dbSNP
rs1479239738 374 dbSNP
rs1368416943 379 dbSNP
rs578166429 399 dbSNP
rs1211334096 400 dbSNP
rs957405909 405 dbSNP
rs1198116969 429 dbSNP
rs1160213931 438 dbSNP
rs1420121739 443 dbSNP
rs1048942591 444 dbSNP
rs888449782 445 dbSNP
rs1394359868 453 dbSNP
rs777821030 459 dbSNP
rs1434337916 460 dbSNP
rs1016134661 464 dbSNP
rs915869369 466 dbSNP
rs1217762964 468 dbSNP
rs1264939892 468 dbSNP
rs1377697167 474 dbSNP
rs1347642767 476 dbSNP
rs11537607 477 dbSNP
rs567449867 492 dbSNP
rs563707076 500 dbSNP
rs770835467 509 dbSNP
rs183116089 522 dbSNP
rs928557639 523 dbSNP
rs1364311604 528 dbSNP
rs1299063378 529 dbSNP
rs1035199895 533 dbSNP
rs187050924 534 dbSNP
rs1400330445 535 dbSNP
rs939896193 548 dbSNP
rs959506757 550 dbSNP
rs991074650 561 dbSNP
rs879060394 562 dbSNP
rs192936575 571 dbSNP
rs1396235655 572 dbSNP
rs915464042 573 dbSNP
rs1036786322 583 dbSNP
rs1430745095 591 dbSNP
rs559537865 605 dbSNP
rs1363985576 614 dbSNP
rs968153899 615 dbSNP
rs773938324 617 dbSNP
rs1332846550 618 dbSNP
rs151258947 619 dbSNP
rs1251284119 620 dbSNP
rs1268306811 620 dbSNP
rs1341226383 621 dbSNP
rs551251219 622 dbSNP
rs1225284695 623 dbSNP
rs1320121606 636 dbSNP
rs889472198 640 dbSNP
rs944457107 641 dbSNP
rs2295491 646 dbSNP
rs1353871773 661 dbSNP
rs1310830070 664 dbSNP
rs530749662 668 dbSNP
rs1276477546 673 dbSNP
rs1489760173 680 dbSNP
rs931776239 682 dbSNP
rs1048973787 691 dbSNP
rs184131690 693 dbSNP
rs1459976806 706 dbSNP
rs1019650220 715 dbSNP
rs116353227 720 dbSNP
rs775085300 725 dbSNP
rs1415277968 726 dbSNP
rs3204117 728 dbSNP
rs1267461308 738 dbSNP
rs1037022015 740 dbSNP
rs1250370213 751 dbSNP
rs1194599708 757 dbSNP
rs1191688336 760 dbSNP
rs1459093607 761 dbSNP
rs3204118 765 dbSNP
rs1063081 768 dbSNP
rs546298462 774 dbSNP
rs1213205480 775 dbSNP
rs1332926750 777 dbSNP
rs566413053 778 dbSNP
rs1286211963 779 dbSNP
rs1246659493 782 dbSNP
rs1450601792 785 dbSNP
rs1170943514 786 dbSNP
rs1306122766 788 dbSNP
rs1035065807 801 dbSNP
rs189445101 804 dbSNP
rs765784366 807 dbSNP
rs1402449607 808 dbSNP
rs957455199 810 dbSNP
rs1012415292 818 dbSNP
rs1391781858 819 dbSNP
rs1294271241 822 dbSNP
rs1022592310 823 dbSNP
rs1393008047 824 dbSNP
rs766523952 828 dbSNP
rs1458679871 829 dbSNP
rs1023032803 832 dbSNP
rs978188414 834 dbSNP
rs1442072877 837 dbSNP
rs970492857 839 dbSNP
rs981463235 844 dbSNP
rs1435722126 852 dbSNP
rs149747048 853 dbSNP
rs961244072 859 dbSNP
rs1350321302 862 dbSNP
rs1259918689 867 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions TZM-bl
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' uggaagggcuGAAGAGGa 5'
                    ||||||| 
Target 5' ---------cCUUCUCCu 3'
 		1 - 9
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM1462574
Method / RBP PAR-CLIP / AGO2
Cell line / Condition TZM-bl / TZM-bl ami BaL
Location of target site ENST00000217233.3 | 3UTR | CCUUCUCCUGCCUCUGAACUGAGCCAAACCUUCAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
158 hsa-miR-5703 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT100581 PIM1 Pim-1 proto-oncogene, serine/threonine kinase 2 2
MIRT134907 CCND2 cyclin D2 2 2
MIRT145067 TNFAIP1 TNF alpha induced protein 1 2 2
MIRT164194 SCOC short coiled-coil protein 2 2
MIRT179547 CAPZA1 capping actin protein of muscle Z-line alpha subunit 1 2 2
MIRT197051 NKIRAS2 NFKB inhibitor interacting Ras like 2 2 2
MIRT202410 RBM38 RNA binding motif protein 38 2 2
MIRT243306 SLC25A36 solute carrier family 25 member 36 2 2
MIRT273441 DAZAP2 DAZ associated protein 2 2 4
MIRT288608 DCAF7 DDB1 and CUL4 associated factor 7 2 2
MIRT324287 LURAP1L leucine rich adaptor protein 1 like 2 2
MIRT338925 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT346169 RAC3 Rac family small GTPase 3 2 2
MIRT370127 TRIB3 tribbles pseudokinase 3 2 2
MIRT442261 FBXW11 F-box and WD repeat domain containing 11 2 2
MIRT443368 PLXNA2 plexin A2 2 2
MIRT443635 ELP6 elongator acetyltransferase complex subunit 6 2 2
MIRT444007 GOLGA8H golgin A8 family member H 2 2
MIRT444019 GOLGA8M golgin A8 family member M 2 2
MIRT444180 HAL histidine ammonia-lyase 2 2
MIRT446553 GOLGA8J golgin A8 family member J 2 2
MIRT448121 CCDC80 coiled-coil domain containing 80 2 2
MIRT449475 ZNF84 zinc finger protein 84 2 2
MIRT449752 SMYD2 SET and MYND domain containing 2 2 2
MIRT450172 KLF7 Kruppel like factor 7 2 2
MIRT451418 TJP3 tight junction protein 3 2 4
MIRT451771 USP36 ubiquitin specific peptidase 36 2 2
MIRT451870 SOD2 superoxide dismutase 2 2 8
MIRT452184 KIAA1456 KIAA1456 2 2
MIRT453514 C14orf144 chromosome 14 open reading frame 144 2 2
MIRT453639 SLC4A2 solute carrier family 4 member 2 2 2
MIRT454010 ALKBH5 alkB homolog 5, RNA demethylase 2 2
MIRT454632 FAM83H family with sequence similarity 83 member H 2 2
MIRT454949 TPM2 tropomyosin 2 2 2
MIRT455358 KDM5C lysine demethylase 5C 2 2
MIRT455591 TAF12 TATA-box binding protein associated factor 12 2 2
MIRT455647 YARS tyrosyl-tRNA synthetase 2 2
MIRT456128 SAMD10 sterile alpha motif domain containing 10 2 2
MIRT456529 TMEM63A transmembrane protein 63A 2 2
MIRT456581 NID1 nidogen 1 2 2
MIRT456780 MTHFSD methenyltetrahydrofolate synthetase domain containing 2 2
MIRT457561 ZNF34 zinc finger protein 34 2 2
MIRT458110 GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 2 2
MIRT458450 RPRM reprimo, TP53 dependent G2 arrest mediator homolog 2 2
MIRT458734 CES2 carboxylesterase 2 2 2
MIRT459767 IDH3A isocitrate dehydrogenase 3 (NAD(+)) alpha 2 2
MIRT459793 POTED POTE ankyrin domain family member D 2 10
MIRT460160 CCL16 C-C motif chemokine ligand 16 2 2
MIRT461799 FXR2 FMR1 autosomal homolog 2 2 2
MIRT462595 MYL12A myosin light chain 12A 2 2
MIRT462708 MAPK13 mitogen-activated protein kinase 13 2 2
MIRT463289 ZFP91 ZFP91 zinc finger protein 2 2
MIRT464780 UBE2G1 ubiquitin conjugating enzyme E2 G1 2 2
MIRT465440 TP53 tumor protein p53 2 2
MIRT465681 TNPO2 transportin 2 2 2
MIRT466543 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT467268 SPOPL speckle type BTB/POZ protein like 2 2
MIRT467430 SND1 staphylococcal nuclease and tudor domain containing 1 2 2
MIRT467587 SLC7A5 solute carrier family 7 member 5 2 6
MIRT469755 RAB2B RAB2B, member RAS oncogene family 2 2
MIRT469984 PTPN14 protein tyrosine phosphatase, non-receptor type 14 2 2
MIRT470183 PSMD11 proteasome 26S subunit, non-ATPase 11 2 2
MIRT471057 PIM2 Pim-2 proto-oncogene, serine/threonine kinase 2 2
MIRT471862 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 4
MIRT473386 MBD4 methyl-CpG binding domain 4, DNA glycosylase 2 6
MIRT473891 M6PR mannose-6-phosphate receptor, cation dependent 2 8
MIRT474002 LRRC20 leucine rich repeat containing 20 2 2
MIRT474031 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT475519 HRK harakiri, BCL2 interacting protein 2 2
MIRT476138 GPR137C G protein-coupled receptor 137C 2 8
MIRT476282 GMFB glia maturation factor beta 2 10
MIRT476364 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT478048 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 10
MIRT479018 COL5A1 collagen type V alpha 1 chain 2 2
MIRT479438 CDKN1A cyclin dependent kinase inhibitor 1A 2 2
MIRT479568 CDC42SE1 CDC42 small effector 1 2 2
MIRT480040 CANX calnexin 2 2
MIRT480213 CABLES1 Cdk5 and Abl enzyme substrate 1 2 2
MIRT482211 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT482676 NXN nucleoredoxin 2 4
MIRT482817 TRAF6 TNF receptor associated factor 6 2 2
MIRT483404 SPATA6 spermatogenesis associated 6 2 4
MIRT483969 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT484204 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT484506 SYT7 synaptotagmin 7 2 2
MIRT485143 RASL10B RAS like family 10 member B 2 2
MIRT487006 C2orf82 chromosome 2 open reading frame 82 2 2
MIRT487924 KCND1 potassium voltage-gated channel subfamily D member 1 2 2
MIRT488393 PDE4DIP phosphodiesterase 4D interacting protein 2 2
MIRT488692 NAT9 N-acetyltransferase 9 (putative) 2 2
MIRT488974 REXO2 RNA exonuclease 2 2 2
MIRT490699 FSTL4 follistatin like 4 2 2
MIRT491740 SEMA3F semaphorin 3F 2 2
MIRT493790 GATA6 GATA binding protein 6 2 2
MIRT494234 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT497254 ELOVL6 ELOVL fatty acid elongase 6 2 2
MIRT501128 SLC2A1 solute carrier family 2 member 1 2 2
MIRT503775 ZNF12 zinc finger protein 12 2 6
MIRT505913 REST RE1 silencing transcription factor 2 2
MIRT506591 MECP2 methyl-CpG binding protein 2 2 4
MIRT507833 CCNT1 cyclin T1 2 2
MIRT510635 TMEM167A transmembrane protein 167A 2 4
MIRT512854 TBC1D13 TBC1 domain family member 13 2 9
MIRT514504 SHISA9 shisa family member 9 2 4
MIRT518899 CDC14B cell division cycle 14B 2 2
MIRT522615 MAP7D1 MAP7 domain containing 1 2 4
MIRT526675 MTMR1 myotubularin related protein 1 2 2
MIRT527325 SIAH3 siah E3 ubiquitin protein ligase family member 3 2 2
MIRT528362 ZMYM1 zinc finger MYM-type containing 1 2 4
MIRT528886 MARC1 mitochondrial amidoxime reducing component 1 2 2
MIRT530656 TRIM56 tripartite motif containing 56 2 2
MIRT537173 GFPT2 glutamine-fructose-6-phosphate transaminase 2 2 4
MIRT547922 HNRNPU heterogeneous nuclear ribonucleoprotein U 2 2
MIRT550416 ORC4 origin recognition complex subunit 4 2 2
MIRT553103 UBXN2A UBX domain protein 2A 2 2
MIRT555885 OTUD7B OTU deubiquitinase 7B 2 4
MIRT556361 MAF MAF bZIP transcription factor 2 2
MIRT557105 HOXA3 homeobox A3 2 2
MIRT560581 LCE1B late cornified envelope 1B 2 2
MIRT560872 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT561529 SOX4 SRY-box 4 2 2
MIRT561989 LRRC58 leucine rich repeat containing 58 2 2
MIRT562048 KPNA6 karyopherin subunit alpha 6 2 2
MIRT562120 IGFBP5 insulin like growth factor binding protein 5 2 2
MIRT562381 EN2 engrailed homeobox 2 2 2
MIRT563935 TAF7 TATA-box binding protein associated factor 7 2 2
MIRT565083 UHRF1BP1 UHRF1 binding protein 1 2 4
MIRT565276 TNFRSF21 TNF receptor superfamily member 21 2 2
MIRT565686 SET SET nuclear proto-oncogene 2 2
MIRT565756 SERTAD2 SERTA domain containing 2 2 2
MIRT568008 CMTM4 CKLF like MARVEL transmembrane domain containing 4 2 2
MIRT569186 LRRC3C leucine rich repeat containing 3C 2 2
MIRT569252 FAM129B family with sequence similarity 129 member B 2 2
MIRT569615 ASTN2 astrotactin 2 2 2
MIRT569690 FMNL3 formin like 3 2 2
MIRT569729 GPR173 G protein-coupled receptor 173 2 2
MIRT569769 SAMD14 sterile alpha motif domain containing 14 2 2
MIRT569822 CRMP1 collapsin response mediator protein 1 2 2
MIRT573272 NCAPH non-SMC condensin I complex subunit H 2 2
MIRT574932 Tbc1d13 TBC1 domain family, member 13 2 6
MIRT612255 ABCC6 ATP binding cassette subfamily C member 6 2 4
MIRT620507 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT627836 POU3F1 POU class 3 homeobox 1 2 2
MIRT630625 ANKRD32 SMC5-SMC6 complex localization factor 1 2 4
MIRT644934 PTCD2 pentatricopeptide repeat domain 2 2 2
MIRT660371 BACH2 BTB domain and CNC homolog 2 2 2
MIRT683345 SCARF1 scavenger receptor class F member 1 2 2
MIRT684975 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT693014 HS2ST1 heparan sulfate 2-O-sulfotransferase 1 2 2
MIRT699483 SLC10A6 solute carrier family 10 member 6 2 2
MIRT703962 EMP2 epithelial membrane protein 2 2 2
MIRT712294 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT715896 SIPA1L1 signal induced proliferation associated 1 like 1 2 2
MIRT716635 DPY19L4 dpy-19 like 4 2 2
MIRT717241 HLA-DRB5 major histocompatibility complex, class II, DR beta 5 2 2
MIRT718163 KIAA1958 KIAA1958 2 2
MIRT723309 PRKCH protein kinase C eta 2 2
MIRT755589 SRC SRC proto-oncogene, non-receptor tyrosine kinase 5 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-5703 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-mir-5703 Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-5703 Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-5703 Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-5703 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-5703 Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)

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