miRTarBase - #MIRT374677


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pre-miRNA Information
pre-miRNA hsa-mir-137   
Genomic Coordinates chr1: 98046070 - 98046171
Description Homo sapiens miR-137 stem-loop
Comment This miRNA sequence is predicted based on homology to a verified miRNA from mouse .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-137
Sequence 59| UUAUUGCUUAAGAAUACGCGUAG |81
Evidence Experimental
Experiments Cloned
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B41RDC miR-137 Safety Biomarker (SAF) Clinical/Experimental Data Expression Decrease Neuron Reverse transcription-polymerase chain reaction
Gene Information
Gene Symbol AGO4   
Synonyms EIF2C4
Description argonaute 4, RISC catalytic component
Transcript NM_017629   
Expression
Putative miRNA Targets on AGO4
3'UTR of AGO4
(miRNA target sites are highlighted)		 
>AGO4|NM_017629|3'UTR
   1 GAGTCTCAGAAAAAGAACTCAACCAATTTGGCACCCCATGCAGCCTCAAAATGTTTCAAATGCCTACCGCCTCTAGATCG
  81 AGCCACGTTGACTTCAGGTGGTCTTCTACCAGCAGCTCGGAATAGTTGCACTGAATCTATACTTTGCAGCACTGTCTGAT
 161 GCGTCAACAAAATTGAGCCATTTTTTTAAAGTAATAGATACTAATAGATTATCTTTTCTGATGCACTGGACTGAATTTTT
 241 ACCTCAATGTGCAAAGGCTGATCAGCCTGAACTTTCTAAAGGACTTTACAAGAAGGGTTTCTATGGAATATTTTGCTAGC
 321 TGTGGTGTTCACCGCATCCCTCTAGTCTTAGAAGAGAAGATTATTCCTTTTTTCTGTAGTCATTGAGTGGGGTATATGCA
 401 TAAGTGGGAGAGAAAAACCAAACAATCTACTTCAGTTCAGTGTAACTATTTAATTGTGTGGGTCCATAGACTTTTTAATG
 481 AAGATTTCTGACTTTGCCACTGTAAATGCCTTTAATGAGCATTAATTTTTGAAAGTTTTACAGAGTTTTATTAGTTTTAC
 561 TACTTTATCTTATTGATCTCTGCAGACTTGTGCTGGTGCAAGTACATGCTGACAGGCAATTTGCACTATATTTGGCTGCA
 641 GATTCAAATAGGCAGTTCTCTTATTTGGTCGACTTTTGTGAATGTGTGACATAAACAGATGTAATGCATGTCACAGTGAC
 721 GGAGATAACACTGCCATGATAAAAGTACTCATGTTTCCCCTATTTGGAAAAAAAAATTGCTTTTAGTATTTTTCCAAGTT
 801 TTCAAAAGTGCCCATTTTATGCTGCTGTGTGGTTTGTTAAATCTAAATGATTTTTAAACTTTTCTCATAGAAACTTAACT
 881 TTGGCAATAAACATTTTTTAAGGTCTCTCCTCTTCCTTCCCCAACAATGTAGTTTTCTAGATGAGATTTCAGTATGATTT
 961 TATCAGCTATTTCTTATATATCATAATCTGGCAATTTCTGAAACCAGTCAGAAAAGACATATATTTCCATGCCTTTTTAA
1041 AGAATTATTTTTACCTGTTTTATATTCACAGTTGGTGTCCTGTCACTTTGTTTTAAAATAAGCTAGAACCAGGATGCTTC
1121 CTTATTGGAAAGGCTTTGCCAGTCCTTAAGGTACAATGAGTGATGCTGCAACTTGCAAATGTACCAGCATTTAAAATTTC
1201 TTTTCCTGGGAATCAAGGTAACTCACACGACTACTTGCAGTACAAATTTTTTGCTTCTCTTTCGACATGAAATGTACTTG
1281 GTGGGTTTTCCTTCCTTTTATTAAACTAAAACTGTGTGGAAAAGGTTGATTTTTCTTAATAGATTCTGGATTCCACTCAC
1361 AGGGAGATGGGATTCCTTTCTTGTCCAAACAAAGGGAGTTGCTCTAAAGCGAGCATCAGTTAAAATGTAGGGGAAAATGT
1441 ATTCTGTATGTAGTGTAGATAATACTTTGTGAATGGACAACAGTTACATAGTGTCTTGGTAGCACCAGCCAGTGTTTCCC
1521 AGCCCAGAGTTTACTGACTTGTAATTCTCTATCCAGGACATCAGGAGTGAGGGATGGAAAAGGGGATAAAAGGCCTGGAG
1601 CCACACTCTATATGGCTGAGGAAGGAGCTAGGGAAAGAGATAGACACAATGGGGTGAAAACAATTTTGCCGCCCCTGCCT
1681 GGAAACTGCTGGTGGGGAAATGATGGTGAAGGGTGTTTGCTTGAACTCATGAGACGGTCCAAATCTCATAAACTAGCCTT
1761 CTCAAAATCCCAGCAATATAAAGCACTGTTTTTCTTCAGTCGTTTAAATAAACTTGTAAATACATTGAAGTTTACATTTC
1841 CATGTGCTGTTGATCAACGGCGCCACCTGTGTTTGCTGAGACTGGTCTCTGAGAGAGTTTTATGTCGATCGAGGCCTGTT
1921 GCTCATTAAGCTGAGTGCAGACGTCCTTAATCCCTGCAGATAGTGGGATGAAAGCAAGTTCTGTAAAATGAAGCACAACA
2001 TAGCCAGGAGTGAAGAGATGGCAGATGTTAATTTCTTAAAATTTTCCTTTTTTTTTTTTTTTTTTGCAAATACCTCACTT
2081 GGATAATACAAATCAGGACATGTTGGTGAGGGGCTGGCTGCTTGGCTGCTGCTTTTATTCACACTTGTTCAGGGAGAGCA
2161 CAGAGAATACCCTTCAGCATGGCCACTCTGGACCCAAGAGGAGGAAAAAACGGAAGCTTTTTTAGGAGAAGGAGGACTTG
2241 CTGGAATCCAAGATGTGAAGAACTCTTGGTGACTGGCTGGCTGGCCAGCGGGCACCACACCTGCACTTGAGTGCCTCGGG
2321 CTTGCTTATTAATAACGCACAGAAGAAGCATCACTTCTCACCATCTCCTGGCATGTATGGAGCAGGGAGCAAGGCTATGT
2401 TCCCGAAAGCCCTGATTAGCTTGTCTTGCTCTACGCTCGACCTCGAACAATACAGCTTGTAAGACCTCAGTCAGTCCTGG
2481 TACACTGGGGTAAATCAGTGTGGTGGTGGAAGAAAAGCCGGGAGGCCTATTTTTATAGGAAAATAGTACCATTAAAGGTG
2561 CAATGCTGTCATTTTGGACAAAAGGAAAGAAATTTGGAAGAGCTGGGATTATTGGCAAAAACTTGCTGAGGGGTGAATCT
2641 TTAGAGCTAATCACTGCAGAATCAGAGTTGCAGCAATATGATTGCAAGCAAGTCTGAATGCATAGTTTTACTTTAATTCG
2721 GCTTGACAATTTGAATAGGTAACCCCCTCGGGACTGACTGAATCGTTATGCATGTGTCAATCAATGGGAGGTGTGCATTC
2801 TCTAGAAGTAGTTTTAGGCTGTTTGGTTTGGTTTTGGTTTTGTTTTTTAAATGCAGCCTGTTGAGGCACTGTCATGTGGT
2881 GTGAAAGATTTAAATGTAGCAACGCTAAAGAGTAATAATTTGGGGATAAGAAGTGGGGACATTGGCCGGGCGCGGTGGCT
2961 CACGCCTGTAATTCCAGCACTTTGGGAGGCCTAGGTGGGCGGATCAGCTGAGGTCGAGAGTTCGAGGCCAGTCTGACCAA
3041 CATGGTGAAACCCCATCTCTACTAAAAATACAGAAAATTAGCTGGGTCTGGTGGTGGATGCCTGTAATCCCAGCTACTCG
3121 GGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGTGGACGGTGCAGTGAGCTATTACTCCAGCCTGGGCAACAAGAG
3201 CGAAACTCTGTCTCAAAAAAAAAAAGGGGGGGGGGGGACATTAAGAGAGTGGTGATGACCCAAATGTTGAACCAATTATG
3281 TTTTGGTGGTGGTGTTCTTAGCTGTTGAATCCTGAATGGTTTATAAAGTGAACTAGCTGGCTTAATGCAGCCAGCGTTCT
3361 GGGCAGCAGAACATATTCATTCTTACTGTAAATTCTATTTGCTGCTTCCAAAGGTGATGATTTTCAAGCAGACATGTTCT
3441 ATATGGTCTGTGTTTTAGGATCTGGTGCCCAGCCTCTATCAGAGCTTGCCTACCTGGCAAAGCTGCCTACCCTTCAAGTG
3521 GGAAAATATAATCCACTGTTTAACAAGGCTCACCCTCTCCACCCTGTCCTAACGACCTTTTGTGAATGTGCTGTGATATT
3601 TTCTTGCTCAATAGCAAGGTGGTAGCTCTGCTTTCATTTTAAGAAAGTGGAGGCTGAGGGCATTGTATCAATACTGTTGC
3681 AACTCCAAGAAGTTTTCCTTGTAAAATTAAAGGAAAGATCTTGTTATTGATTAACCATTTTCTTATGCCTTGCTATTGAC
3761 ATATTCATGCTCTTTCTACGTCTAGTGGCTGAAAATGTTTGCATTTGTTCATTTGACTAATGGTGTGATTTTTGTTTCTA
3841 TATTATTAGACCTGTAATGTTTTAAAATGTATTTTATTAAATTTGGACTGGATGTATGTCTCTAGCAATACGAGGTACTT
3921 TCTAAACTATTAAGGGAGGGGTTGTATCCTCATGTTGAGATAAGATGATGGTCGTTTAAATTTTGCAATTTTTTTTGGCC
4001 TGCAGGGATATTTTGTGTTTATGTGTCCAAAAAAGGAATAAATTGGCATTCTTGTGCCAAAAGTTGTTTTTCCTGTCAAT
4081 TGTCTAATAAGTATGCAGTACACTGTAATGGCAACATACATGGTTGCTTTATAAAAACAGTTTCCTCAGTATGAGAAATT
4161 TTACAAAGAACAGTGGAAAAACTTTGTGTTTTTAACTCTTGGGTCTCCCTATTTTTAAAAATTGCTATTTGGTATACAAT
4241 TATTATGTGTCAATTAAAACTAAAATAAAACTTTTAAAAAAGAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaugcGCAUA-AGAAUUCGUUAUu 5'
               :|||| |||  ||||||| 
Target 5' ctggaTGTATGTCTCTAGCAATAc 3'
 3888 - 3911 162.00 -12.80
2 
miRNA  3' gaUG-CGCAUAAG----AAU-UCGUUAUu 5'
            || ||  | ||    ||: ||||||| 
Target 5' tcACTGCAGAATCAGAGTTGCAGCAATAt 3'
 2651 - 2679 147.00 -7.94
3 
miRNA  3' gaugcGCAUAAGAA-UUCGUUAUu 5'
               | | ||:|| |||:|||| 
Target 5' tgagcCATTTTTTTAAAGTAATAg 3'
 174 - 197 146.00 -7.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31575475 21 COSMIC
COSN26965481 39 COSMIC
COSN30119414 42 COSMIC
COSN30717423 67 COSMIC
COSN31577960 69 COSMIC
COSN31503950 91 COSMIC
COSN30119063 130 COSMIC
COSN30174550 134 COSMIC
COSN16474292 142 COSMIC
COSN32056901 164 COSMIC
COSN8467957 208 COSMIC
COSN31532455 235 COSMIC
COSN26679018 297 COSMIC
COSN30545461 334 COSMIC
COSN30545408 397 COSMIC
COSN31538513 455 COSMIC
COSN31567711 549 COSMIC
COSN6034707 551 COSMIC
COSN505709 900 COSMIC
COSN23102546 1039 COSMIC
COSN16128037 1079 COSMIC
COSN29183985 1169 COSMIC
COSN15744275 1208 COSMIC
COSN21191410 1270 COSMIC
COSN26561403 1270 COSMIC
COSN31545805 1335 COSMIC
COSN31524110 1342 COSMIC
COSN31533317 1363 COSMIC
COSN32056341 1457 COSMIC
COSN14663847 1640 COSMIC
COSN25899345 1683 COSMIC
COSN26557103 1698 COSMIC
COSN31566324 1737 COSMIC
COSN31544475 1848 COSMIC
COSN31490705 1879 COSMIC
COSN30175746 1907 COSMIC
COSN17719610 2191 COSMIC
COSN24547689 2316 COSMIC
COSN4902222 2974 COSMIC
COSN23883685 3226 COSMIC
COSN7218251 3229 COSMIC
COSN22972796 4112 COSMIC
rs145204399 2529 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs548583111 5 dbSNP
rs749597375 15 dbSNP
rs369254382 16 dbSNP
rs1174106171 18 dbSNP
rs773829850 19 dbSNP
rs759207550 27 dbSNP
rs1328255061 29 dbSNP
rs1166007216 31 dbSNP
rs1027869878 33 dbSNP
rs767117969 35 dbSNP
rs774964472 36 dbSNP
rs1345220961 40 dbSNP
rs760187816 41 dbSNP
rs763948680 43 dbSNP
rs753800535 44 dbSNP
rs756953858 46 dbSNP
rs371692112 50 dbSNP
rs750224521 53 dbSNP
rs866017928 62 dbSNP
rs570201005 68 dbSNP
rs961178265 69 dbSNP
rs990833188 70 dbSNP
rs1293783216 77 dbSNP
rs1309266427 81 dbSNP
rs564842095 87 dbSNP
rs537508781 89 dbSNP
rs1168133173 94 dbSNP
rs1279465390 102 dbSNP
rs1355901115 106 dbSNP
rs1442539371 110 dbSNP
rs1301930201 111 dbSNP
rs946678459 114 dbSNP
rs548431581 119 dbSNP
rs558886695 120 dbSNP
rs1317894454 134 dbSNP
rs1213151975 136 dbSNP
rs1035522094 137 dbSNP
rs959852740 142 dbSNP
rs751784916 146 dbSNP
rs1474994399 148 dbSNP
rs1184402099 149 dbSNP
rs923848829 151 dbSNP
rs1255691575 155 dbSNP
rs935293020 163 dbSNP
rs1051354986 164 dbSNP
rs1258126768 176 dbSNP
rs1421222412 182 dbSNP
rs1475072362 188 dbSNP
rs1184531162 194 dbSNP
rs1421339385 197 dbSNP
rs967128258 206 dbSNP
rs1174835282 208 dbSNP
rs890940752 210 dbSNP
rs756625148 212 dbSNP
rs748185749 215 dbSNP
rs181092178 217 dbSNP
rs1179671707 228 dbSNP
rs1313007384 233 dbSNP
rs1340415384 236 dbSNP
rs535021719 248 dbSNP
rs764534975 282 dbSNP
rs1433373158 289 dbSNP
rs954147710 290 dbSNP
rs1278456373 291 dbSNP
rs1350400082 295 dbSNP
rs1211662067 303 dbSNP
rs1315428894 315 dbSNP
rs985532448 317 dbSNP
rs1360101537 328 dbSNP
rs1285453225 333 dbSNP
rs898252618 334 dbSNP
rs1213498304 335 dbSNP
rs1243791313 341 dbSNP
rs1287277169 350 dbSNP
rs944169123 350 dbSNP
rs370578139 355 dbSNP
rs995162841 355 dbSNP
rs918816522 358 dbSNP
rs757968345 360 dbSNP
rs1048100488 366 dbSNP
rs1398461391 369 dbSNP
rs566837789 393 dbSNP
rs905528528 397 dbSNP
rs886672250 399 dbSNP
rs1436193274 406 dbSNP
rs1345881634 409 dbSNP
rs1236394031 412 dbSNP
rs937120950 412 dbSNP
rs1235251404 418 dbSNP
rs1005111617 425 dbSNP
rs1035692632 430 dbSNP
rs1348558389 436 dbSNP
rs755260736 445 dbSNP
rs1281035413 449 dbSNP
rs1225603646 464 dbSNP
rs575329335 467 dbSNP
rs1447561618 468 dbSNP
rs990949289 470 dbSNP
rs34406706 472 dbSNP
rs143513803 475 dbSNP
rs1250860208 483 dbSNP
rs968139789 484 dbSNP
rs1213409156 493 dbSNP
rs1362863958 509 dbSNP
rs1468155546 516 dbSNP
rs1159856985 518 dbSNP
rs1409329508 523 dbSNP
rs1461418104 527 dbSNP
rs895674300 531 dbSNP
rs535157556 532 dbSNP
rs1243450637 534 dbSNP
rs1397081638 536 dbSNP
rs1442118153 540 dbSNP
rs1485972509 555 dbSNP
rs1334262571 570 dbSNP
rs1241245806 575 dbSNP
rs1280250856 584 dbSNP
rs1010044318 588 dbSNP
rs979389866 591 dbSNP
rs574770631 597 dbSNP
rs781380102 601 dbSNP
rs748563021 611 dbSNP
rs986706790 614 dbSNP
rs912477038 619 dbSNP
rs1183315686 622 dbSNP
rs541470090 626 dbSNP
rs904398224 629 dbSNP
rs1474607637 636 dbSNP
rs1000516737 649 dbSNP
rs1192670805 650 dbSNP
rs562935613 662 dbSNP
rs1032376042 671 dbSNP
rs942472885 675 dbSNP
rs770166564 677 dbSNP
rs1402353977 691 dbSNP
rs1413393627 692 dbSNP
rs1329814690 693 dbSNP
rs1331864484 695 dbSNP
rs1339886651 696 dbSNP
rs1413013045 708 dbSNP
rs1291355269 720 dbSNP
rs919662188 721 dbSNP
rs931073240 722 dbSNP
rs1176001179 726 dbSNP
rs965548039 729 dbSNP
rs1337241902 731 dbSNP
rs185475220 737 dbSNP
rs1047270620 740 dbSNP
rs188774332 743 dbSNP
rs1185249913 752 dbSNP
rs918748758 753 dbSNP
rs931617998 758 dbSNP
rs543878427 759 dbSNP
rs1371648880 763 dbSNP
rs149653098 768 dbSNP
rs200764891 768 dbSNP
rs1375137249 769 dbSNP
rs1436061690 778 dbSNP
rs1357260901 787 dbSNP
rs936986807 788 dbSNP
rs1294801022 789 dbSNP
rs545838762 798 dbSNP
rs983992558 798 dbSNP
rs12068665 812 dbSNP
rs945874788 828 dbSNP
rs560795148 829 dbSNP
rs886748444 837 dbSNP
rs779618327 842 dbSNP
rs1002958840 843 dbSNP
rs1056677112 861 dbSNP
rs1443206633 864 dbSNP
rs1275321117 867 dbSNP
rs1349906987 869 dbSNP
rs1041588613 873 dbSNP
rs72902959 880 dbSNP
rs1012360391 883 dbSNP
rs1194411532 910 dbSNP
rs1394683034 912 dbSNP
rs1452855158 923 dbSNP
rs1175797225 929 dbSNP
rs1286060321 929 dbSNP
rs1453161918 933 dbSNP
rs1000143431 937 dbSNP
rs142922183 940 dbSNP
rs1383694239 941 dbSNP
rs1321022036 942 dbSNP
rs1317354211 952 dbSNP
rs145121227 953 dbSNP
rs181662005 967 dbSNP
rs1231561544 971 dbSNP
rs889809062 977 dbSNP
rs1305191855 979 dbSNP
rs1006866156 981 dbSNP
rs370121658 988 dbSNP
rs1000937018 989 dbSNP
rs965492965 992 dbSNP
rs1487167307 1023 dbSNP
rs1031518674 1034 dbSNP
rs35830885 1034 dbSNP
rs1247763908 1043 dbSNP
rs1252723497 1055 dbSNP
rs1467436035 1061 dbSNP
rs546498377 1079 dbSNP
rs1395925744 1098 dbSNP
rs759577521 1113 dbSNP
rs1157390230 1123 dbSNP
rs1361962074 1125 dbSNP
rs1455245888 1142 dbSNP
rs1410603911 1150 dbSNP
rs984410297 1152 dbSNP
rs1458161112 1157 dbSNP
rs1327492039 1158 dbSNP
rs1438442447 1158 dbSNP
rs1164402401 1161 dbSNP
rs1390287648 1164 dbSNP
rs186180533 1165 dbSNP
rs912479556 1179 dbSNP
rs560369048 1200 dbSNP
rs528493903 1201 dbSNP
rs975224813 1205 dbSNP
rs1216017335 1211 dbSNP
rs1253855251 1213 dbSNP
rs1480458859 1220 dbSNP
rs1175731227 1223 dbSNP
rs1252697057 1227 dbSNP
rs770366133 1229 dbSNP
rs931147078 1241 dbSNP
rs1159726814 1243 dbSNP
rs1417158579 1247 dbSNP
rs1046773819 1258 dbSNP
rs767910224 1264 dbSNP
rs938357174 1277 dbSNP
rs1057233771 1297 dbSNP
rs192454199 1300 dbSNP
rs896731234 1301 dbSNP
rs1350806584 1302 dbSNP
rs916910029 1313 dbSNP
rs1012477931 1324 dbSNP
rs571529792 1324 dbSNP
rs1041843244 1330 dbSNP
rs925830679 1332 dbSNP
rs1270832079 1336 dbSNP
rs1045310133 1340 dbSNP
rs904003790 1347 dbSNP
rs138991047 1361 dbSNP
rs1253298236 1383 dbSNP
rs1031046006 1389 dbSNP
rs769556789 1404 dbSNP
rs1180282476 1411 dbSNP
rs957048467 1412 dbSNP
rs1187379117 1414 dbSNP
rs1235108872 1416 dbSNP
rs1473090921 1420 dbSNP
rs1008222142 1426 dbSNP
rs750509761 1428 dbSNP
rs1476297378 1434 dbSNP
rs1041101480 1435 dbSNP
rs373322053 1450 dbSNP
rs994288445 1451 dbSNP
rs537601965 1455 dbSNP
rs1019649646 1461 dbSNP
rs964057333 1489 dbSNP
rs1026127014 1499 dbSNP
rs1408277668 1508 dbSNP
rs952924592 1514 dbSNP
rs975298921 1516 dbSNP
rs1297974014 1519 dbSNP
rs759099836 1525 dbSNP
rs552604547 1530 dbSNP
rs570841477 1533 dbSNP
rs1210209956 1558 dbSNP
rs1371108247 1560 dbSNP
rs952535406 1569 dbSNP
rs983058532 1573 dbSNP
rs1212083632 1575 dbSNP
rs958988821 1586 dbSNP
rs1413902498 1595 dbSNP
rs41267261 1599 dbSNP
rs1391610155 1602 dbSNP
rs1449743439 1606 dbSNP
rs1357191208 1607 dbSNP
rs1392657677 1609 dbSNP
rs1436047492 1611 dbSNP
rs1335446085 1621 dbSNP
rs916939390 1624 dbSNP
rs1429030163 1632 dbSNP
rs938456831 1642 dbSNP
rs775249849 1646 dbSNP
rs1366412182 1648 dbSNP
rs1233784714 1649 dbSNP
rs915555969 1651 dbSNP
rs925665032 1655 dbSNP
rs553147747 1662 dbSNP
rs948405310 1671 dbSNP
rs1050214942 1672 dbSNP
rs760416269 1672 dbSNP
rs1249623801 1685 dbSNP
rs1045258191 1691 dbSNP
rs910380397 1695 dbSNP
rs12059301 1696 dbSNP
rs936852281 1703 dbSNP
rs1040298418 1705 dbSNP
rs1277344330 1712 dbSNP
rs535712205 1722 dbSNP
rs150822052 1727 dbSNP
rs1161939666 1736 dbSNP
rs139277923 1737 dbSNP
rs545598133 1740 dbSNP
rs1440639332 1741 dbSNP
rs75380846 1752 dbSNP
rs1373538874 1753 dbSNP
rs1476427531 1756 dbSNP
rs1188422583 1757 dbSNP
rs1276522535 1758 dbSNP
rs1372731842 1764 dbSNP
rs183954294 1771 dbSNP
rs372613235 1775 dbSNP
rs1221943678 1782 dbSNP
rs1269945929 1784 dbSNP
rs1005592339 1789 dbSNP
rs1169758383 1796 dbSNP
rs761743586 1799 dbSNP
rs1250725308 1803 dbSNP
rs1390911505 1803 dbSNP
rs567869900 1807 dbSNP
rs1199164719 1808 dbSNP
rs958849709 1819 dbSNP
rs1468169992 1824 dbSNP
rs1311058731 1830 dbSNP
rs952770194 1840 dbSNP
rs967082959 1843 dbSNP
rs1393109087 1847 dbSNP
rs1406130522 1848 dbSNP
rs1328463474 1852 dbSNP
rs1396397607 1852 dbSNP
rs1317129656 1855 dbSNP
rs977456195 1859 dbSNP
rs751696926 1860 dbSNP
rs77235743 1862 dbSNP
rs985864795 1863 dbSNP
rs944500743 1867 dbSNP
rs1015868833 1868 dbSNP
rs1206757212 1882 dbSNP
rs529202922 1884 dbSNP
rs781435069 1888 dbSNP
rs1234196223 1891 dbSNP
rs1253137823 1891 dbSNP
rs553721833 1892 dbSNP
rs1278815569 1895 dbSNP
rs1186464681 1905 dbSNP
rs929997633 1907 dbSNP
rs1047548647 1908 dbSNP
rs375907047 1909 dbSNP
rs992509889 1911 dbSNP
rs550864030 1912 dbSNP
rs563686618 1917 dbSNP
rs530968252 1924 dbSNP
rs1195666972 1936 dbSNP
rs978437995 1940 dbSNP
rs11803314 1943 dbSNP
rs570971040 1944 dbSNP
rs1453932347 1946 dbSNP
rs1052719133 1947 dbSNP
rs903393458 1953 dbSNP
rs1396829134 1959 dbSNP
rs1337100254 1961 dbSNP
rs1466319812 1962 dbSNP
rs1274679165 1965 dbSNP
rs1485072646 1966 dbSNP
rs528567219 1967 dbSNP
rs1209288402 1970 dbSNP
rs1258960362 1971 dbSNP
rs892598913 1974 dbSNP
rs879024299 1984 dbSNP
rs1443336761 1994 dbSNP
rs944227254 1995 dbSNP
rs1157747320 2004 dbSNP
rs546800455 2009 dbSNP
rs1371518139 2018 dbSNP
rs1382573620 2020 dbSNP
rs1451516597 2025 dbSNP
rs1169489485 2027 dbSNP
rs1394492796 2031 dbSNP
rs1007235543 2036 dbSNP
rs568268323 2038 dbSNP
rs1301010763 2044 dbSNP
rs1230101175 2048 dbSNP
rs1297901523 2048 dbSNP
rs1317426641 2048 dbSNP
rs1346513083 2048 dbSNP
rs1404340992 2048 dbSNP
rs67520708 2048 dbSNP
rs1258258135 2050 dbSNP
rs1320890913 2050 dbSNP
rs1346370676 2052 dbSNP
rs1205091914 2061 dbSNP
rs1369519213 2064 dbSNP
rs899954683 2065 dbSNP
rs1301811821 2066 dbSNP
rs1038175983 2067 dbSNP
rs1234657051 2068 dbSNP
rs1260484674 2069 dbSNP
rs1349061326 2079 dbSNP
rs1210822306 2088 dbSNP
rs368851852 2090 dbSNP
rs185979298 2092 dbSNP
rs1468045206 2098 dbSNP
rs1466454010 2100 dbSNP
rs11263829 2111 dbSNP
rs144303118 2116 dbSNP
rs539449101 2124 dbSNP
rs1027014249 2126 dbSNP
rs985897391 2129 dbSNP
rs888350428 2138 dbSNP
rs1004514445 2144 dbSNP
rs1302707069 2165 dbSNP
rs1015526487 2183 dbSNP
rs1181067487 2194 dbSNP
rs771688182 2195 dbSNP
rs919097368 2202 dbSNP
rs1209815855 2205 dbSNP
rs1361844452 2207 dbSNP
rs557468262 2209 dbSNP
rs984710019 2212 dbSNP
rs1268090172 2213 dbSNP
rs1418594786 2219 dbSNP
rs1180918209 2229 dbSNP
rs1393302384 2233 dbSNP
rs1409736363 2242 dbSNP
rs1459375060 2255 dbSNP
rs778144896 2256 dbSNP
rs1367756997 2264 dbSNP
rs1159678197 2266 dbSNP
rs941340518 2269 dbSNP
rs865849110 2277 dbSNP
rs1456016646 2281 dbSNP
rs111482723 2283 dbSNP
rs1294937713 2286 dbSNP
rs538769349 2290 dbSNP
rs894529522 2291 dbSNP
rs969815429 2292 dbSNP
rs1046359668 2296 dbSNP
rs1229361730 2297 dbSNP
rs1293020918 2301 dbSNP
rs1334285931 2305 dbSNP
rs1223982294 2318 dbSNP
rs1230637836 2319 dbSNP
rs1480348444 2329 dbSNP
rs1205076838 2333 dbSNP
rs572900555 2337 dbSNP
rs1334481817 2338 dbSNP
rs1212107292 2340 dbSNP
rs767551038 2341 dbSNP
rs1182835875 2343 dbSNP
rs1421837784 2350 dbSNP
rs1488886134 2353 dbSNP
rs148747333 2361 dbSNP
rs74653221 2375 dbSNP
rs892820965 2378 dbSNP
rs1371903420 2384 dbSNP
rs1410924870 2388 dbSNP
rs925634245 2399 dbSNP
rs1007199651 2404 dbSNP
rs955744728 2405 dbSNP
rs1017370353 2406 dbSNP
rs988763649 2408 dbSNP
rs1226499533 2413 dbSNP
rs74607403 2418 dbSNP
rs1416944627 2429 dbSNP
rs544402724 2432 dbSNP
rs538945087 2435 dbSNP
rs1041266561 2436 dbSNP
rs921334427 2439 dbSNP
rs932745011 2440 dbSNP
rs1298048812 2443 dbSNP
rs1166353603 2445 dbSNP
rs1391420403 2446 dbSNP
rs1429837867 2446 dbSNP
rs1394996715 2447 dbSNP
rs1357989869 2448 dbSNP
rs1412022873 2449 dbSNP
rs950558709 2466 dbSNP
rs1361720354 2468 dbSNP
rs1433092404 2469 dbSNP
rs1355287046 2470 dbSNP
rs1048529368 2485 dbSNP
rs1342957509 2500 dbSNP
rs1233734715 2507 dbSNP
rs888418058 2520 dbSNP
rs775807658 2521 dbSNP
rs1310411390 2522 dbSNP
rs1212194827 2524 dbSNP
rs1004226504 2525 dbSNP
rs1315115896 2526 dbSNP
rs145204399 2529 dbSNP
rs779537984 2537 dbSNP
rs533072741 2543 dbSNP
rs369712764 2551 dbSNP
rs1449533846 2558 dbSNP
rs555153431 2576 dbSNP
rs991409188 2589 dbSNP
rs1416604750 2591 dbSNP
rs915909215 2594 dbSNP
rs1263116863 2595 dbSNP
rs78403130 2597 dbSNP
rs1045802432 2607 dbSNP
rs924793466 2609 dbSNP
rs1183177225 2615 dbSNP
rs1022782995 2619 dbSNP
rs934817846 2629 dbSNP
rs1055124527 2634 dbSNP
rs375152095 2638 dbSNP
rs893355117 2648 dbSNP
rs1220820331 2653 dbSNP
rs528589735 2663 dbSNP
rs1007813033 2677 dbSNP
rs969763055 2679 dbSNP
rs745409324 2702 dbSNP
rs190797025 2715 dbSNP
rs1269608328 2716 dbSNP
rs901498461 2720 dbSNP
rs997696141 2721 dbSNP
rs1026037839 2743 dbSNP
rs999871505 2746 dbSNP
rs1032769579 2748 dbSNP
rs1391527097 2750 dbSNP
rs1432152372 2751 dbSNP
rs1309237014 2752 dbSNP
rs955858375 2754 dbSNP
rs1455953462 2761 dbSNP
rs1389882533 2766 dbSNP
rs200436813 2766 dbSNP
rs1321845022 2770 dbSNP
rs988533886 2772 dbSNP
rs1304752781 2776 dbSNP
rs1016136859 2777 dbSNP
rs370147334 2785 dbSNP
rs529481711 2799 dbSNP
rs550742924 2801 dbSNP
rs569584430 2803 dbSNP
rs1226316486 2806 dbSNP
rs915940544 2807 dbSNP
rs1293490577 2809 dbSNP
rs1329614447 2814 dbSNP
rs147615092 2826 dbSNP
rs1287378006 2827 dbSNP
rs976897957 2844 dbSNP
rs1251686537 2849 dbSNP
rs557735451 2849 dbSNP
rs1471874531 2853 dbSNP
rs182530337 2854 dbSNP
rs1345403864 2869 dbSNP
rs934828447 2871 dbSNP
rs1048926699 2876 dbSNP
rs909973770 2878 dbSNP
rs1406007377 2881 dbSNP
rs1307544385 2887 dbSNP
rs940016441 2889 dbSNP
rs533886333 2890 dbSNP
rs1037069490 2902 dbSNP
rs895724427 2904 dbSNP
rs775303460 2905 dbSNP
rs1350876902 2913 dbSNP
rs746614362 2917 dbSNP
rs555534459 2937 dbSNP
rs1054670013 2938 dbSNP
rs1282041542 2939 dbSNP
rs1184461301 2943 dbSNP
rs573756803 2944 dbSNP
rs187324612 2948 dbSNP
rs544464784 2949 dbSNP
rs1039288073 2952 dbSNP
rs1449548542 2952 dbSNP
rs1169718356 2953 dbSNP
rs1395034474 2954 dbSNP
rs768340585 2955 dbSNP
rs1178646615 2957 dbSNP
rs1442197662 2958 dbSNP
rs776555710 2964 dbSNP
rs1370389006 2981 dbSNP
rs1473227803 2982 dbSNP
rs1168210290 2983 dbSNP
rs901524871 2995 dbSNP
rs1431773837 3002 dbSNP
rs1318867691 3003 dbSNP
rs1033172888 3016 dbSNP
rs1170398443 3017 dbSNP
rs997160503 3023 dbSNP
rs955846630 3024 dbSNP
rs1331904475 3029 dbSNP
rs1342067787 3038 dbSNP
rs886149503 3054 dbSNP
rs1010301765 3055 dbSNP
rs1018633880 3065 dbSNP
rs556074428 3071 dbSNP
rs577877786 3072 dbSNP
rs1302525512 3073 dbSNP
rs1012142749 3076 dbSNP
rs1024819168 3077 dbSNP
rs1199279064 3083 dbSNP
rs1258629071 3088 dbSNP
rs761500828 3090 dbSNP
rs981428882 3092 dbSNP
rs1451384069 3098 dbSNP
rs1189339318 3103 dbSNP
rs544927942 3120 dbSNP
rs1316189716 3121 dbSNP
rs1032088912 3143 dbSNP
rs575127851 3155 dbSNP
rs1470187527 3158 dbSNP
rs1319458327 3161 dbSNP
rs1269638565 3163 dbSNP
rs984347912 3164 dbSNP
rs1295634514 3168 dbSNP
rs1330029061 3176 dbSNP
rs990222250 3177 dbSNP
rs1258352678 3187 dbSNP
rs914770187 3194 dbSNP
rs1442826343 3197 dbSNP
rs1208547966 3198 dbSNP
rs1266438388 3202 dbSNP
rs1192500048 3203 dbSNP
rs1189479545 3206 dbSNP
rs769111106 3213 dbSNP
rs1196664592 3215 dbSNP
rs1250641033 3215 dbSNP
rs1379360485 3215 dbSNP
rs1477312983 3219 dbSNP
rs1480629998 3220 dbSNP
rs747341841 3221 dbSNP
rs975003526 3222 dbSNP
rs1426308626 3223 dbSNP
rs1400496831 3224 dbSNP
rs76637434 3224 dbSNP
rs923511796 3224 dbSNP
rs761454863 3225 dbSNP
rs764726433 3225 dbSNP
rs1304020256 3226 dbSNP
rs1346739078 3226 dbSNP
rs149478166 3226 dbSNP
rs750119864 3226 dbSNP
rs758086450 3226 dbSNP
rs12562615 3227 dbSNP
rs960479536 3228 dbSNP
rs932982879 3229 dbSNP
rs1047428246 3230 dbSNP
rs886096458 3231 dbSNP
rs764793353 3232 dbSNP
rs1275371110 3233 dbSNP
rs1365683925 3235 dbSNP
rs1372266333 3236 dbSNP
rs386630311 3236 dbSNP
rs1306724251 3237 dbSNP
rs1352709700 3237 dbSNP
rs76361293 3238 dbSNP
rs1289784349 3239 dbSNP
rs894996026 3251 dbSNP
rs564528115 3253 dbSNP
rs1024851766 3264 dbSNP
rs114543266 3276 dbSNP
rs940149202 3280 dbSNP
rs1224339886 3281 dbSNP
rs1482779694 3285 dbSNP
rs540218933 3287 dbSNP
rs375108953 3290 dbSNP
rs1249595555 3295 dbSNP
rs999842730 3296 dbSNP
rs192148278 3302 dbSNP
rs956219004 3303 dbSNP
rs1255252675 3317 dbSNP
rs1044252428 3319 dbSNP
rs1421636518 3320 dbSNP
rs200177278 3332 dbSNP
rs367727843 3332 dbSNP
rs113774917 3335 dbSNP
rs1428623779 3346 dbSNP
rs1164558528 3354 dbSNP
rs1021686608 3356 dbSNP
rs759645999 3357 dbSNP
rs1302596995 3358 dbSNP
rs1324068497 3360 dbSNP
rs1054324075 3380 dbSNP
rs974866418 3383 dbSNP
rs891520032 3387 dbSNP
rs1009964120 3388 dbSNP
rs1019121377 3390 dbSNP
rs1226333557 3399 dbSNP
rs1350942727 3402 dbSNP
rs1309140669 3411 dbSNP
rs1205161710 3419 dbSNP
rs984095671 3429 dbSNP
rs907557116 3430 dbSNP
rs529345570 3442 dbSNP
rs762319047 3447 dbSNP
rs1448328199 3454 dbSNP
rs894859941 3457 dbSNP
rs995846220 3463 dbSNP
rs947805151 3467 dbSNP
rs1410973824 3473 dbSNP
rs1175996941 3476 dbSNP
rs1357723692 3479 dbSNP
rs1467950793 3480 dbSNP
rs550806196 3498 dbSNP
rs1028577999 3507 dbSNP
rs1433204289 3510 dbSNP
rs1291169767 3513 dbSNP
rs1299853025 3519 dbSNP
rs908038473 3523 dbSNP
rs1215019479 3530 dbSNP
rs1277912050 3532 dbSNP
rs113583821 3557 dbSNP
rs1205383199 3564 dbSNP
rs752879778 3574 dbSNP
rs374057841 3575 dbSNP
rs1243288553 3578 dbSNP
rs1475460643 3588 dbSNP
rs1191122920 3589 dbSNP
rs984685068 3590 dbSNP
rs1423737787 3600 dbSNP
rs1435243562 3601 dbSNP
rs1017127599 3613 dbSNP
rs1177547468 3615 dbSNP
rs891812011 3617 dbSNP
rs1011546805 3618 dbSNP
rs1021719196 3620 dbSNP
rs961864376 3625 dbSNP
rs972814865 3626 dbSNP
rs764204348 3627 dbSNP
rs1254406064 3645 dbSNP
rs1274158631 3660 dbSNP
rs1483625824 3664 dbSNP
rs1225308345 3667 dbSNP
rs1283633383 3670 dbSNP
rs562890907 3684 dbSNP
rs950050296 3686 dbSNP
rs1285998533 3690 dbSNP
rs1366956508 3691 dbSNP
rs1447052876 3692 dbSNP
rs1220235265 3709 dbSNP
rs754274480 3712 dbSNP
rs757527925 3714 dbSNP
rs1411603090 3718 dbSNP
rs1473793384 3719 dbSNP
rs1160498301 3720 dbSNP
rs1409052687 3721 dbSNP
rs1163876608 3755 dbSNP
rs1418955931 3756 dbSNP
rs779591562 3768 dbSNP
rs1351712418 3778 dbSNP
rs77661035 3780 dbSNP
rs935956490 3781 dbSNP
rs1349652237 3787 dbSNP
rs1413956229 3789 dbSNP
rs1331737397 3792 dbSNP
rs983739321 3798 dbSNP
rs1350887181 3806 dbSNP
rs551750751 3816 dbSNP
rs908085714 3822 dbSNP
rs1269059966 3824 dbSNP
rs1054797678 3839 dbSNP
rs891597763 3841 dbSNP
rs867317778 3845 dbSNP
rs1251801340 3848 dbSNP
rs945879668 3851 dbSNP
rs567137155 3852 dbSNP
rs757993639 3858 dbSNP
rs779638475 3868 dbSNP
rs1254554307 3886 dbSNP
rs1444320781 3888 dbSNP
rs533797708 3898 dbSNP
rs1188578758 3909 dbSNP
rs1241590040 3911 dbSNP
rs1028694422 3912 dbSNP
rs890018892 3913 dbSNP
rs746496902 3915 dbSNP
rs548994988 3928 dbSNP
rs1390736127 3933 dbSNP
rs1446747106 3942 dbSNP
rs927840176 3950 dbSNP
rs1384345890 3955 dbSNP
rs567408409 3965 dbSNP
rs1340610471 3974 dbSNP
rs1052368181 3975 dbSNP
rs1442214333 3989 dbSNP
rs558885361 3989 dbSNP
rs868159126 3997 dbSNP
rs1317285691 4000 dbSNP
rs961527527 4006 dbSNP
rs994780673 4011 dbSNP
rs996298668 4018 dbSNP
rs1300390421 4029 dbSNP
rs776126727 4037 dbSNP
rs1460348337 4040 dbSNP
rs1169580992 4045 dbSNP
rs560607755 4046 dbSNP
rs1413755673 4052 dbSNP
rs1233214410 4067 dbSNP
rs954914736 4072 dbSNP
rs1005421937 4073 dbSNP
rs1015091371 4076 dbSNP
rs971480323 4080 dbSNP
rs1201182391 4087 dbSNP
rs1362407109 4093 dbSNP
rs1230184521 4099 dbSNP
rs980054001 4113 dbSNP
rs973614561 4117 dbSNP
rs1344742829 4121 dbSNP
rs144568712 4123 dbSNP
rs957612778 4148 dbSNP
rs1265417731 4153 dbSNP
rs1461915391 4154 dbSNP
rs1208353962 4157 dbSNP
rs969004607 4163 dbSNP
rs990048240 4165 dbSNP
rs1181866617 4177 dbSNP
rs913144443 4178 dbSNP
rs927667567 4183 dbSNP
rs935178724 4183 dbSNP
rs945899901 4186 dbSNP
rs1040265809 4189 dbSNP
rs1052736512 4194 dbSNP
rs923003307 4204 dbSNP
rs1196745881 4212 dbSNP
rs931745495 4217 dbSNP
rs1382120368 4221 dbSNP
rs1383478777 4228 dbSNP
rs1319517621 4232 dbSNP
rs946644248 4234 dbSNP
rs183131271 4235 dbSNP
rs1285514894 4237 dbSNP
rs1324736756 4239 dbSNP
rs1228005468 4241 dbSNP
rs1478237466 4252 dbSNP
rs1486872583 4267 dbSNP
rs1205845612 4272 dbSNP
rs887423744 4274 dbSNP
rs1450921428 4281 dbSNP
rs1197194746 4283 dbSNP
rs1006310057 4284 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions BC-3
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM796039. RNA binding protein: AGO2. Condition:4-Thiouridine PAR-CLIP data was present in GSM796040. RNA binding protein: AGO2. Condition:4-Thiouridine ...

- Gottwein E; Corcoran DL; Mukherjee N; et al., 2011, Cell host & microbe.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gaugcgcauaagaAUUCGUUAUu 5'
                       | :|||||| 
Target 5' -------------UUGGCAAUAa 3'
 		1 - 10
Article - Gottwein E; Corcoran DL; Mukherjee N; et al.
- Cell host & microbe, 2011
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and EBV-encoded microRNAs (miRNAs) in PELs suggests a role for these miRNAs in latency and lymphomagenesis. Using PAR-CLIP, a technology which allows the direct and transcriptome-wide identification of miRNA targets, we delineate the target sites for all viral and cellular miRNAs expressed in PEL cell lines. The resulting data set revealed that KSHV miRNAs directly target more than 2000 cellular mRNAs, including many involved in pathways relevant to KSHV pathogenesis. Moreover, 58% of these mRNAs are also targeted by EBV miRNAs, via distinct binding sites. In addition to a known viral analog of cellular miR-155, we show that KSHV encodes a viral miRNA that mimics cellular miR-142-3p function. In summary, this study identifies an extensive list of KSHV miRNA targets, which are likely to influence viral replication and pathogenesis.
LinkOut: [PMID: 22100165]
CLIP-seq Support 1 for dataset GSM796039
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000373210.3 | 3UTR | UUGGCAAUAAACAUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM796040
Method / RBP PAR-CLIP / AGO2
Cell line / Condition BC-3 / 4-Thiouridine
Location of target site ENST00000373210.3 | 3UTR | UUGGCAAUAAACAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22100165 / GSE32109
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
140 hsa-miR-137 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT002489 E2F6 E2F transcription factor 6 4 1
MIRT002490 CDK6 cyclin dependent kinase 6 4 7
MIRT004004 NCOA2 nuclear receptor coactivator 2 4 1
MIRT004579 KDM1A lysine demethylase 1A 5 3
MIRT005485 CDC42 cell division cycle 42 4 4
MIRT005605 CTBP1 C-terminal binding protein 1 4 1
MIRT005883 MITF melanogenesis associated transcription factor 3 1
MIRT006329 PTGS2 prostaglandin-endoperoxide synthase 2 2 1
MIRT006957 ESRRA estrogen related receptor alpha 1 1
MIRT007068 ZNF804A zinc finger protein 804A 1 1
MIRT007092 YBX1 Y-box binding protein 1 3 3
MIRT007252 CSE1L chromosome segregation 1 like 2 1
MIRT007346 PXN paxillin 3 1
MIRT053056 GLIPR1 GLI pathogenesis related 1 3 1
MIRT053225 MET MET proto-oncogene, receptor tyrosine kinase 3 1
MIRT054547 FUNDC1 FUN14 domain containing 1 3 1
MIRT054568 BNIP3L BCL2 interacting protein 3 like 3 1
MIRT090615 PLS1 plastin 1 2 2
MIRT093393 TMA16 translation machinery associated 16 homolog 2 2
MIRT109230 VMA21 VMA21, vacuolar ATPase assembly factor 2 6
MIRT153687 NCOA3 nuclear receptor coactivator 3 2 2
MIRT170929 FOXK1 forkhead box K1 2 2
MIRT219251 RREB1 ras responsive element binding protein 1 2 2
MIRT259552 KLHL15 kelch like family member 15 2 4
MIRT271869 ZNF678 zinc finger protein 678 2 2
MIRT280623 BCL11B B-cell CLL/lymphoma 11B 2 8
MIRT293284 DR1 down-regulator of transcription 1 2 2
MIRT314017 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 8
MIRT374677 AGO4 argonaute 4, RISC catalytic component 2 2
MIRT437385 FMNL2 formin like 2 1 1
MIRT437406 RORA RAR related orphan receptor A 1 1
MIRT437423 KIT KIT proto-oncogene receptor tyrosine kinase 3 1
MIRT437424 AKT2 AKT serine/threonine kinase 2 5 4
MIRT437425 TGFB2 transforming growth factor beta 2 3 1
MIRT437804 SERPINA3 serpin family A member 3 1 1
MIRT437978 COX2 cytochrome c oxidase subunit II 3 1
MIRT438078 TRIM13 tripartite motif containing 13 4 1
MIRT438287 TBX3 T-box 3 1 1
MIRT438288 KLF4 Kruppel like factor 4 1 1
MIRT438537 MTDH metadherin 2 1
MIRT438757 Nr1i3 nuclear receptor subfamily 1, group I, member 3 2 1
MIRT442564 CCDC59 coiled-coil domain containing 59 2 2
MIRT442778 JAG1 jagged 1 2 2
MIRT444302 SREK1IP1 SREK1 interacting protein 1 2 2
MIRT446969 SLCO4C1 solute carrier organic anion transporter family member 4C1 2 2
MIRT448824 FKBP1A FK506 binding protein 1A 2 4
MIRT453617 SNRPE small nuclear ribonucleoprotein polypeptide E 2 4
MIRT459217 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT463490 ZC3H11A zinc finger CCCH-type containing 11A 2 12
MIRT470084 PTGES2 prostaglandin E synthase 2 2 2
MIRT475876 H3F3C H3 histone family member 3C 2 10
MIRT475912 H3F3B H3 histone family member 3B 2 8
MIRT476669 FUT11 fucosyltransferase 11 2 10
MIRT477346 EOGT EGF domain specific O-linked N-acetylglucosamine transferase 2 4
MIRT477596 EIF1 eukaryotic translation initiation factor 1 2 10
MIRT478367 DDI2 DNA damage inducible 1 homolog 2 2 2
MIRT479111 CNN2 calponin 2 2 2
MIRT482926 CTPS2 CTP synthase 2 2 2
MIRT485083 SNRK SNF related kinase 2 12
MIRT497120 NBEAL1 neurobeachin like 1 2 2
MIRT498029 UBXN4 UBX domain protein 4 2 8
MIRT500603 UBE2Z ubiquitin conjugating enzyme E2 Z 2 4
MIRT500927 SSFA2 sperm specific antigen 2 2 8
MIRT504324 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT504647 RPL9 ribosomal protein L9 2 6
MIRT506304 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT508007 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT510538 XKR7 XK related 7 2 2
MIRT513051 LYPD6 LY6/PLAUR domain containing 6 2 6
MIRT515223 COX20 COX20, cytochrome c oxidase assembly factor 2 8
MIRT519857 ZFP62 ZFP62 zinc finger protein 2 6
MIRT520508 TRAM2 translocation associated membrane protein 2 2 6
MIRT522047 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 4
MIRT524479 CHRM3 cholinergic receptor muscarinic 3 2 4
MIRT526904 ZNF772 zinc finger protein 772 2 6
MIRT527862 SLC39A14 solute carrier family 39 member 14 2 2
MIRT528601 ZNF326 zinc finger protein 326 2 2
MIRT532950 ZNF24 zinc finger protein 24 2 4
MIRT536275 LMOD2 leiomodin 2 2 2
MIRT537045 GRAMD4 GRAM domain containing 4 2 2
MIRT537124 GOLGA3 golgin A3 2 4
MIRT538884 BTBD1 BTB domain containing 1 2 2
MIRT541457 AURKA aurora kinase A 2 2
MIRT542924 HOXC8 homeobox C8 2 2
MIRT544580 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT545175 RFTN2 raftlin family member 2 2 2
MIRT545248 GTF2E1 general transcription factor IIE subunit 1 2 2
MIRT546473 SLC1A5 solute carrier family 1 member 5 2 2
MIRT547523 MARCH9 membrane associated ring-CH-type finger 9 2 2
MIRT548071 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT548200 FNIP1 folliculin interacting protein 1 2 2
MIRT551216 CIDEC cell death inducing DFFA like effector c 2 2
MIRT553046 USP28 ubiquitin specific peptidase 28 2 2
MIRT553875 SUPT7L SPT7 like, STAGA complex gamma subunit 2 4
MIRT554026 SPCS3 signal peptidase complex subunit 3 2 2
MIRT554153 SLX4 SLX4 structure-specific endonuclease subunit 2 2
MIRT554192 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT554362 SFXN5 sideroflexin 5 2 4
MIRT555349 PPP1R37 protein phosphatase 1 regulatory subunit 37 2 2
MIRT555822 PAX9 paired box 9 2 2
MIRT555866 PAIP1 poly(A) binding protein interacting protein 1 2 2
MIRT555931 NUP43 nucleoporin 43 2 2
MIRT555993 NFYB nuclear transcription factor Y subunit beta 2 2
MIRT556429 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT556582 LHFPL2 LHFPL tetraspan subfamily member 2 2 4
MIRT557220 HNRNPDL heterogeneous nuclear ribonucleoprotein D like 2 2
MIRT558490 DBN1 drebrin 1 2 2
MIRT560986 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT562291 GLO1 glyoxalase I 2 2
MIRT564093 TLR3 toll like receptor 3 2 2
MIRT565312 TMEM41A transmembrane protein 41A 2 2
MIRT565424 TEF TEF, PAR bZIP transcription factor 2 2
MIRT566946 LIMCH1 LIM and calponin homology domains 1 2 2
MIRT572369 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT686211 ZNF267 zinc finger protein 267 2 2
MIRT686935 SFT2D3 SFT2 domain containing 3 2 2
MIRT687448 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT710856 COQ7 coenzyme Q7, hydroxylase 2 2
MIRT719484 RBM27 RNA binding motif protein 27 2 2
MIRT719813 TXNDC17 thioredoxin domain containing 17 2 2
MIRT720076 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT723920 ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif 15 2 2
MIRT731305 CUL4A cullin 4A 3 1
MIRT732128 BMP7 bone morphogenetic protein 7 2 1
MIRT732466 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 3 0
MIRT732962 TNC tenascin C 1 0
MIRT734856 KDM4A lysine demethylase 4A 3 0
MIRT735625 MEF2A myocyte enhancer factor 2A 2 0
MIRT735795 IL6 interleukin 6 3 0
MIRT736333 DELE1 KIAA0141 2 0
MIRT736610 RUNX2 runt related transcription factor 2 3 0
MIRT736830 NOTCH1 notch 1 3 0
MIRT736888 KCNA2 potassium voltage-gated channel subfamily A member 2 3 0
MIRT737349 EGFR epidermal growth factor receptor 3 0
MIRT755368 GLS glutaminase 2 1
MIRT755431 SPHK2 sphingosine kinase 2 3 1
MIRT756119 USP30 ubiquitin specific peptidase 30 4 1
MIRT756144 XIAP X-linked inhibitor of apoptosis 3 1
MIRT756170 COL5A1 collagen type V alpha 1 chain 3 1
MIRT756171 FSTL1 follistatin like 1 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-137 Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-137 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-137 Emodin NULL 3220 Microarray K562 cells 23744534 2013 down-regualted
miR-137 Emodin NULL 3220 Quantitative real-time PCR K562 cells 23744534 2013 down-regualted
miR-137 Olea europaea leaf extract NULL NULL Quantitative real-time PCR Glioblastoma multiforme tumors cell lines 25232498 2014 up-regualted
miR-137 Formaldehyde NULL 712 Microarray Human lung epithelial cells (A549) 21147603 2011 down-regulated
miR-137 Ginsenoside Rh2 NULL 119307 Microarray human glioma cells U251 21372826 2011 up-regulated
miR-137 Interleukin 13 (IL-13) NULL NULL Quantitative real-time PCR esophageal squamous cells 22453679 2012 up-regulated
miR-137 1,2,6-Tri-O-galloyl-beta-D-glucopyranose NULL NULL Microarray HepG2 hepatocarcinoma cells. 22506400 2011 down-regulated
miR-137 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-137 Olea europaea leaf extract NULL NULL Quantitative real-time PCR glioblastoma cells. 22722712 2012 up-regulated
miR-137 Temozolomide approved 5394 Quantitative real-time PCR glioblastoma cells. 22722712 2012 up-regulated
miR-137 Nicotine approved 89594 Microarray Rat adrenal pheochromocytoma PC12 cell 18845019 2009 up-regulated
miR-137 Capecitabine approved 60953 Quantitative real-time PCR rectal cancer 18695884 2008 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-137 Cisplatin 5460033 NSC119875 approved sensitive Low Breast Cancer cell line (MDA-MB-231)
hsa-mir-137 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-137 Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-137 Cisplatin 5460033 NSC119875 approved sensitive cell line (W1)
hsa-mir-137 Doxorubicin 31703 NSC123127 approved sensitive cell line (W1)
hsa-mir-137 Topotecan 60699 NSC609699 approved resistant cell line (W1)

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