pre-miRNA Information
pre-miRNA hsa-mir-1303   
Genomic Coordinates chr5: 154685776 - 154685861
Synonyms MIRN1303, hsa-mir-1303, MIR1303
Description Homo sapiens miR-1303 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-1303
Sequence 52| UUUAGAGACGGGGUCUUGCUCU |73
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 5 + 154685830 23291724, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs370437195 6 dbSNP
rs1195001383 7 dbSNP
rs546614687 8 dbSNP
rs762579883 9 dbSNP
rs766041486 10 dbSNP
rs751079975 12 dbSNP
rs888516744 13 dbSNP
rs566454487 14 dbSNP
rs766973220 15 dbSNP
rs1474274822 17 dbSNP
rs753222192 18 dbSNP
rs1230907999 19 dbSNP
rs756552638 22 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol NDUFB5   
Synonyms CISGDH, SGDH
Description NADH:ubiquinone oxidoreductase subunit B5
Transcript NM_002492   
Expression
Putative miRNA Targets on NDUFB5
3'UTR of NDUFB5
(miRNA target sites are highlighted)
>NDUFB5|NM_002492|3'UTR
   1 GCATTTTTTTCTCCAAATACAAAGTATATTCTCTTTATTGGAAAATAAATTAATAAATATATTCTGTATTTTTGCTCTCC
  81 GTGAAAAACAAAAGAGCCTCTGACATTACTGTCTCTCAGTGTTGGTTCAGATTGAGGCTTTTGTTTGAGGAGTTTGGCTT
 161 CCAGTCCCCAAAGAAGGTTTAAAATGTACTAATAAAAACTGGAGAAATAGGAATTTGTGAACTCCTAAAATTGTAGCAAC
 241 TTTGAAAGGTTAGTGTTTTATTTACCTGACAAATGGAAGTTATAGAAGTCTAATAATGTTAAGCACCAGTAATTATAGTA
 321 TTTTGTACAAATGCCTGTACTGTAGATGTCTGTATTATTGAGGGGCAACTCAGGATTTTAAGTTCCATAAAGTATTGAAC
 401 CAACTCTAAAATGTTAACTCCTTAATAAACAGATTCTCAGTAAACAAATTTTAAAGTTTAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' ucucGUUCUGG-GGCAGAGAUUu 5'
              ::| |:: |:|||||| | 
Target 5' cctcTGACATTACTGTCTCTCAg 3'
97 - 119 122.00 -12.90
2
miRNA  3' ucucguucuggggcaGAGAUUu 5'
                         |||||| 
Target 5' aaagtattgaaccaaCTCTAAa 3'
389 - 410 120.00 -11.30
3
miRNA  3' ucucgUUC-UGGGGCAGAGAUuu 5'
               ||| |: :: |||:||  
Target 5' atacaAAGTATATTCTCTTTAtt 3'
17 - 39 113.00 -5.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN199344 3 COSMIC
COSN30178731 29 COSMIC
COSN19706068 32 COSMIC
COSN20467869 44 COSMIC
COSN30166186 51 COSMIC
COSN30155528 72 COSMIC
COSN30492206 81 COSMIC
COSN30160139 118 COSMIC
COSN27946090 386 COSMIC
COSN22244351 467 COSMIC
COSN19243873 532 COSMIC
COSN6755934 1174 COSMIC
COSN24944025 1304 COSMIC
COSN23988366 1364 COSMIC
COSN7838031 2146 COSMIC
COSN32072480 2240 COSMIC
COSN14860170 2337 COSMIC
COSN29038726 2497 COSMIC
COSN29356950 2567 COSMIC
COSN25346984 2681 COSMIC
COSN26264738 2734 COSMIC
COSN1272612 2911 COSMIC
COSN9536668 3085 COSMIC
COSN16688440 3181 COSMIC
COSN6755935 3481 COSMIC
COSN22732128 3489 COSMIC
COSN26878457 3503 COSMIC
COSN25745276 3594 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs372520411 4 dbSNP
rs752365229 4 dbSNP
rs199822602 5 dbSNP
rs1370916167 7 dbSNP
rs748655682 11 dbSNP
rs770127096 16 dbSNP
rs1394497325 17 dbSNP
rs778173196 21 dbSNP
rs1158200346 25 dbSNP
rs749522854 31 dbSNP
rs1402479997 37 dbSNP
rs1417813349 40 dbSNP
rs958565910 47 dbSNP
rs1365435179 52 dbSNP
rs1252947766 56 dbSNP
rs1006429565 60 dbSNP
rs1288972562 61 dbSNP
rs1435702609 66 dbSNP
rs551658223 71 dbSNP
rs1307926250 75 dbSNP
rs1209947580 80 dbSNP
rs565616650 81 dbSNP
rs886469879 82 dbSNP
rs1230123791 86 dbSNP
rs1253349390 89 dbSNP
rs962244207 90 dbSNP
rs531098525 97 dbSNP
rs1278728300 99 dbSNP
rs1178209360 103 dbSNP
rs550567033 106 dbSNP
rs1446451765 111 dbSNP
rs190982816 114 dbSNP
rs1029987426 116 dbSNP
rs536365075 133 dbSNP
rs1024412586 139 dbSNP
rs183909850 140 dbSNP
rs910264180 146 dbSNP
rs149627280 152 dbSNP
rs188902247 158 dbSNP
rs1001719111 165 dbSNP
rs1033630133 167 dbSNP
rs1464796411 171 dbSNP
rs957608924 176 dbSNP
rs566831168 178 dbSNP
rs1336910908 182 dbSNP
rs1329792371 195 dbSNP
rs914177701 207 dbSNP
rs989088098 209 dbSNP
rs945602289 216 dbSNP
rs528631280 220 dbSNP
rs1046075 224 dbSNP
rs1449829201 236 dbSNP
rs1046410530 238 dbSNP
rs1283582748 240 dbSNP
rs538873041 246 dbSNP
rs1216219001 250 dbSNP
rs1437292536 263 dbSNP
rs913559185 267 dbSNP
rs966381456 274 dbSNP
rs987585347 275 dbSNP
rs911651643 276 dbSNP
rs1158955456 281 dbSNP
rs1236570939 284 dbSNP
rs938138627 285 dbSNP
rs879002913 286 dbSNP
rs1038861000 307 dbSNP
rs920452812 308 dbSNP
rs558465059 309 dbSNP
rs1250693948 317 dbSNP
rs1189949521 334 dbSNP
rs1464921646 339 dbSNP
rs1006069117 341 dbSNP
rs766337484 342 dbSNP
rs1208088822 359 dbSNP
rs1279061801 363 dbSNP
rs1235371626 364 dbSNP
rs886417587 376 dbSNP
rs190568638 381 dbSNP
rs1046199162 383 dbSNP
rs897769409 386 dbSNP
rs548278866 401 dbSNP
rs905939556 409 dbSNP
rs1002066879 412 dbSNP
rs1030039848 414 dbSNP
rs1033162294 415 dbSNP
rs1361324165 420 dbSNP
rs561842954 424 dbSNP
rs751707741 428 dbSNP
rs1010464580 434 dbSNP
rs1392908832 447 dbSNP
rs1017378351 461 dbSNP
rs1020550198 472 dbSNP
rs1418120700 474 dbSNP
rs1184779895 475 dbSNP
rs201034695 475 dbSNP
rs1237925865 482 dbSNP
rs1188751032 486 dbSNP
rs200229857 487 dbSNP
rs1477659491 488 dbSNP
rs1176793849 490 dbSNP
rs1329798004 490 dbSNP
rs1484541104 491 dbSNP
rs1430957537 492 dbSNP
rs1230847588 494 dbSNP
rs1412306514 494 dbSNP
rs1332893958 497 dbSNP
rs955461263 500 dbSNP
rs958003188 509 dbSNP
rs1212824879 511 dbSNP
rs1296196966 517 dbSNP
rs1294405114 519 dbSNP
rs796654851 519 dbSNP
rs1374000668 521 dbSNP
rs1309511629 523 dbSNP
rs372841307 527 dbSNP
rs989688605 529 dbSNP
rs1223887814 530 dbSNP
rs1353474887 531 dbSNP
rs147514377 531 dbSNP
rs1491443888 532 dbSNP
rs957642159 532 dbSNP
rs113142510 533 dbSNP
rs1182268340 533 dbSNP
rs1232704536 533 dbSNP
rs1250110044 533 dbSNP
rs1273880298 533 dbSNP
rs1469906918 533 dbSNP
rs59680377 533 dbSNP
rs750458055 533 dbSNP
rs758713412 533 dbSNP
rs796598475 533 dbSNP
rs1284226126 535 dbSNP
rs1333352321 535 dbSNP
rs1270503070 537 dbSNP
rs1428721596 540 dbSNP
rs990831311 541 dbSNP
rs1325890917 544 dbSNP
rs1217646747 546 dbSNP
rs1278028304 551 dbSNP
rs1304469469 552 dbSNP
rs1371168821 553 dbSNP
rs1388149392 553 dbSNP
rs1226788688 556 dbSNP
rs1324654535 556 dbSNP
rs914044755 560 dbSNP
rs1159029495 562 dbSNP
rs1447593636 562 dbSNP
rs945683205 564 dbSNP
rs1157275805 565 dbSNP
rs3832244 565 dbSNP
rs1218559363 566 dbSNP
rs1261648062 568 dbSNP
rs1193091980 569 dbSNP
rs966331695 573 dbSNP
rs182790954 577 dbSNP
rs1488201292 578 dbSNP
rs1264504905 580 dbSNP
rs561369622 584 dbSNP
rs1485785180 590 dbSNP
rs1259319938 595 dbSNP
rs538090149 602 dbSNP
rs938022428 606 dbSNP
rs1476850871 614 dbSNP
rs1302192638 616 dbSNP
rs1231472745 621 dbSNP
rs1366717580 625 dbSNP
rs1019063868 627 dbSNP
rs1318935268 629 dbSNP
rs1171579968 631 dbSNP
rs187297711 632 dbSNP
rs1435029219 635 dbSNP
rs888561129 635 dbSNP
rs1401933300 637 dbSNP
rs974927472 644 dbSNP
rs1156844848 660 dbSNP
rs1359805260 661 dbSNP
rs920398861 666 dbSNP
rs1374863117 672 dbSNP
rs1194593811 685 dbSNP
rs191828691 701 dbSNP
rs983293613 704 dbSNP
rs1329086639 707 dbSNP
rs1486176581 710 dbSNP
rs1434595058 713 dbSNP
rs1274414069 718 dbSNP
rs1279226737 719 dbSNP
rs913390913 728 dbSNP
rs993290237 730 dbSNP
rs1270252845 742 dbSNP
rs1284565371 745 dbSNP
rs1225981893 746 dbSNP
rs1353576054 746 dbSNP
rs1223824477 749 dbSNP
rs1415192067 751 dbSNP
rs878939562 751 dbSNP
rs1271514148 752 dbSNP
rs1312573848 754 dbSNP
rs1185422539 756 dbSNP
rs1190670916 756 dbSNP
rs1194764514 756 dbSNP
rs1257248828 756 dbSNP
rs1273182614 756 dbSNP
rs1275024370 756 dbSNP
rs1336824551 756 dbSNP
rs1439204306 756 dbSNP
rs1467190868 756 dbSNP
rs1475763971 756 dbSNP
rs200055605 756 dbSNP
rs371909723 756 dbSNP
rs56727188 756 dbSNP
rs1233821271 757 dbSNP
rs1450167665 759 dbSNP
rs1291225876 760 dbSNP
rs1444025306 761 dbSNP
rs7428555 762 dbSNP
rs1329736311 763 dbSNP
rs1233085841 768 dbSNP
rs58128576 769 dbSNP
rs9713324 769 dbSNP
rs201326272 770 dbSNP
rs1163225432 777 dbSNP
rs1176205801 778 dbSNP
rs114868874 780 dbSNP
rs2339845 781 dbSNP
rs1425244768 784 dbSNP
rs1054790114 786 dbSNP
rs1388310675 788 dbSNP
rs1404543462 789 dbSNP
rs576859144 793 dbSNP
rs1254320592 794 dbSNP
rs916269603 797 dbSNP
rs1213712998 805 dbSNP
rs1323209577 806 dbSNP
rs1336553973 817 dbSNP
rs545622184 818 dbSNP
rs1307212579 819 dbSNP
rs2339846 820 dbSNP
rs950043867 826 dbSNP
rs1247355118 827 dbSNP
rs1441638152 834 dbSNP
rs1394431789 838 dbSNP
rs531133625 839 dbSNP
rs753044762 840 dbSNP
rs1209598441 841 dbSNP
rs1409135413 845 dbSNP
rs905885067 846 dbSNP
rs1468294000 847 dbSNP
rs1396443164 858 dbSNP
rs1017670644 872 dbSNP
rs1193755186 877 dbSNP
rs544471617 883 dbSNP
rs547381585 892 dbSNP
rs957842329 903 dbSNP
rs1217829498 904 dbSNP
rs1439228025 904 dbSNP
rs563695171 912 dbSNP
rs1021162950 913 dbSNP
rs966854135 917 dbSNP
rs1305847088 934 dbSNP
rs1444639059 938 dbSNP
rs1185409248 941 dbSNP
rs1235144496 946 dbSNP
rs1054558749 947 dbSNP
rs928234977 948 dbSNP
rs1433499290 950 dbSNP
rs1346249444 951 dbSNP
rs1473214304 956 dbSNP
rs1318079855 964 dbSNP
rs959594618 966 dbSNP
rs990807151 971 dbSNP
rs146764559 979 dbSNP
rs893287750 985 dbSNP
rs1010415328 991 dbSNP
rs1168250745 998 dbSNP
rs1398309497 1004 dbSNP
rs1392723637 1005 dbSNP
rs909864213 1007 dbSNP
rs941492961 1010 dbSNP
rs778341615 1018 dbSNP
rs1213419598 1023 dbSNP
rs1020497844 1024 dbSNP
rs561233758 1027 dbSNP
rs1211824548 1046 dbSNP
rs929135686 1048 dbSNP
rs1299266500 1064 dbSNP
rs1216337879 1068 dbSNP
rs1008916830 1072 dbSNP
rs1270077599 1075 dbSNP
rs1339199521 1078 dbSNP
rs533494109 1082 dbSNP
rs1377622355 1096 dbSNP
rs1313188990 1109 dbSNP
rs1433705513 1111 dbSNP
rs1357011995 1113 dbSNP
rs1171905560 1115 dbSNP
rs1018599219 1131 dbSNP
rs1418735346 1150 dbSNP
rs187771591 1161 dbSNP
rs546675312 1163 dbSNP
rs1027362164 1170 dbSNP
rs779339773 1173 dbSNP
rs951848628 1175 dbSNP
rs1257960991 1179 dbSNP
rs1188991059 1180 dbSNP
rs983241673 1182 dbSNP
rs1254444435 1183 dbSNP
rs1206744709 1186 dbSNP
rs1308131256 1194 dbSNP
rs1272977858 1197 dbSNP
rs547411211 1201 dbSNP
rs907752784 1204 dbSNP
rs1257021301 1208 dbSNP
rs770660984 1209 dbSNP
rs1201651310 1217 dbSNP
rs1414472172 1221 dbSNP
rs981797414 1226 dbSNP
rs550053800 1228 dbSNP
rs927288989 1231 dbSNP
rs1010532855 1233 dbSNP
rs1021133014 1251 dbSNP
rs1168529509 1262 dbSNP
rs1462937261 1269 dbSNP
rs937359324 1271 dbSNP
rs1054508651 1275 dbSNP
rs62291842 1291 dbSNP
rs796722055 1294 dbSNP
rs1254394339 1298 dbSNP
rs1374589706 1301 dbSNP
rs1476717069 1302 dbSNP
rs1168874407 1308 dbSNP
rs946150672 1310 dbSNP
rs532461028 1313 dbSNP
rs959646759 1316 dbSNP
rs1337586066 1324 dbSNP
rs891316980 1326 dbSNP
rs1008451219 1334 dbSNP
rs1400100096 1338 dbSNP
rs1395976446 1339 dbSNP
rs1040378184 1341 dbSNP
rs910093446 1342 dbSNP
rs963040770 1345 dbSNP
rs900126685 1353 dbSNP
rs115535330 1354 dbSNP
rs192525220 1356 dbSNP
rs934045146 1360 dbSNP
rs1365322226 1365 dbSNP
rs951796180 1373 dbSNP
rs1004613642 1374 dbSNP
rs1379850235 1387 dbSNP
rs1419913348 1387 dbSNP
rs1014748440 1395 dbSNP
rs911719720 1398 dbSNP
rs185587490 1401 dbSNP
rs971652744 1402 dbSNP
rs981359880 1404 dbSNP
rs943308200 1407 dbSNP
rs1039366825 1409 dbSNP
rs927206793 1410 dbSNP
rs760165806 1413 dbSNP
rs554936745 1425 dbSNP
rs1235920471 1430 dbSNP
rs1371055303 1432 dbSNP
rs1302668515 1437 dbSNP
rs1192629519 1439 dbSNP
rs1386981482 1444 dbSNP
rs1269287870 1446 dbSNP
rs1452729085 1450 dbSNP
rs1480901906 1461 dbSNP
rs1042034449 1468 dbSNP
rs902297113 1471 dbSNP
rs1178437069 1472 dbSNP
rs1198847375 1476 dbSNP
rs1431960272 1478 dbSNP
rs566170829 1481 dbSNP
rs768921844 1491 dbSNP
rs1159707417 1494 dbSNP
rs914598294 1500 dbSNP
rs1398583009 1501 dbSNP
rs1298005043 1502 dbSNP
rs776854351 1504 dbSNP
rs1388163654 1507 dbSNP
rs140332898 1508 dbSNP
rs1311167141 1515 dbSNP
rs1328165874 1517 dbSNP
rs1017616601 1519 dbSNP
rs962968050 1522 dbSNP
rs973167416 1525 dbSNP
rs1288126555 1527 dbSNP
rs1436800185 1533 dbSNP
rs1351463690 1535 dbSNP
rs143457973 1536 dbSNP
rs1041836769 1538 dbSNP
rs1375336482 1542 dbSNP
rs1215751240 1544 dbSNP
rs1292249495 1550 dbSNP
rs760660039 1552 dbSNP
rs569226240 1559 dbSNP
rs1485799261 1575 dbSNP
rs1265517211 1588 dbSNP
rs955476284 1589 dbSNP
rs1198250357 1596 dbSNP
rs944204839 1598 dbSNP
rs143094604 1602 dbSNP
rs1039922109 1609 dbSNP
rs1315896356 1612 dbSNP
rs1294916300 1616 dbSNP
rs1415099279 1630 dbSNP
rs1250604841 1638 dbSNP
rs1382205106 1640 dbSNP
rs911271290 1641 dbSNP
rs1398721966 1644 dbSNP
rs900076518 1661 dbSNP
rs1422029478 1664 dbSNP
rs553477793 1666 dbSNP
rs1048692850 1668 dbSNP
rs1236582361 1669 dbSNP
rs1184916085 1672 dbSNP
rs1439111710 1673 dbSNP
rs915162655 1677 dbSNP
rs946639039 1691 dbSNP
rs1456390300 1696 dbSNP
rs189325321 1699 dbSNP
rs1389270298 1700 dbSNP
rs1291483029 1705 dbSNP
rs1366431732 1709 dbSNP
rs1355339765 1710 dbSNP
rs1283894090 1713 dbSNP
rs1004562893 1720 dbSNP
rs1310847803 1725 dbSNP
rs776448725 1729 dbSNP
rs1239349168 1730 dbSNP
rs938980130 1735 dbSNP
rs558178216 1738 dbSNP
rs1323339851 1739 dbSNP
rs1003110459 1740 dbSNP
rs1219080723 1741 dbSNP
rs1328485288 1743 dbSNP
rs545555131 1754 dbSNP
rs1056148353 1758 dbSNP
rs558744149 1765 dbSNP
rs894868481 1770 dbSNP
rs1034224850 1781 dbSNP
rs1488296013 1787 dbSNP
rs1161152615 1791 dbSNP
rs1470965263 1803 dbSNP
rs1199451895 1813 dbSNP
rs1240117577 1824 dbSNP
rs1012846524 1829 dbSNP
rs1456034282 1832 dbSNP
rs1254858950 1834 dbSNP
rs1214239602 1844 dbSNP
rs1017084709 1856 dbSNP
rs34130218 1859 dbSNP
rs1178628890 1862 dbSNP
rs1415131411 1866 dbSNP
rs1353144073 1870 dbSNP
rs1310194335 1872 dbSNP
rs898771326 1876 dbSNP
rs1425969960 1878 dbSNP
rs763062858 1882 dbSNP
rs766645310 1888 dbSNP
rs1025690473 1895 dbSNP
rs1163160671 1902 dbSNP
rs533028230 1904 dbSNP
rs575470365 1906 dbSNP
rs1321993979 1907 dbSNP
rs986765762 1909 dbSNP
rs990093319 1915 dbSNP
rs1402763693 1919 dbSNP
rs1385251837 1929 dbSNP
rs1157654639 1932 dbSNP
rs1437351716 1935 dbSNP
rs1332884326 1939 dbSNP
rs544380919 1946 dbSNP
rs1244866813 1956 dbSNP
rs1195083133 1959 dbSNP
rs964138665 1962 dbSNP
rs967390380 1963 dbSNP
rs561293331 1969 dbSNP
rs946662766 1971 dbSNP
rs181664564 1973 dbSNP
rs944171513 1974 dbSNP
rs540632046 1976 dbSNP
rs1433390025 1987 dbSNP
rs71310388 1987 dbSNP
rs921466089 1994 dbSNP
rs1341517054 1996 dbSNP
rs75051175 1999 dbSNP
rs150360309 2001 dbSNP
rs1176194200 2011 dbSNP
rs1413355507 2012 dbSNP
rs1423031278 2014 dbSNP
rs1307800544 2022 dbSNP
rs1475659458 2023 dbSNP
rs137980375 2024 dbSNP
rs1191170363 2027 dbSNP
rs1259828669 2028 dbSNP
rs947816942 2029 dbSNP
rs149046279 2031 dbSNP
rs1311658244 2046 dbSNP
rs756753380 2048 dbSNP
rs1216817067 2050 dbSNP
rs1198055214 2066 dbSNP
rs1277969441 2066 dbSNP
rs1398496424 2066 dbSNP
rs778253749 2078 dbSNP
rs1038976972 2096 dbSNP
rs994704538 2100 dbSNP
rs759291680 2101 dbSNP
rs531564538 2103 dbSNP
rs1036080716 2105 dbSNP
rs1466091964 2107 dbSNP
rs906943091 2114 dbSNP
rs891356514 2116 dbSNP
rs1002648436 2125 dbSNP
rs1168313356 2136 dbSNP
rs1238087434 2140 dbSNP
rs1034581831 2142 dbSNP
rs1008252808 2147 dbSNP
rs1018271152 2148 dbSNP
rs1413533730 2151 dbSNP
rs1478353076 2152 dbSNP
rs1235818066 2158 dbSNP
rs894324739 2158 dbSNP
rs964507510 2160 dbSNP
rs1458628723 2161 dbSNP
rs1257920067 2166 dbSNP
rs1011476176 2168 dbSNP
rs184634001 2170 dbSNP
rs1217234296 2174 dbSNP
rs1021555480 2175 dbSNP
rs1337362416 2178 dbSNP
rs967337019 2181 dbSNP
rs1227376541 2190 dbSNP
rs1011655801 2191 dbSNP
rs539776656 2196 dbSNP
rs967914293 2201 dbSNP
rs1464681072 2203 dbSNP
rs1329200027 2208 dbSNP
rs142989645 2216 dbSNP
rs977864527 2216 dbSNP
rs1019652515 2220 dbSNP
rs1334277213 2223 dbSNP
rs965828428 2223 dbSNP
rs975553386 2224 dbSNP
rs1411845972 2226 dbSNP
rs1440370550 2226 dbSNP
rs535096281 2226 dbSNP
rs879063908 2226 dbSNP
rs923877274 2227 dbSNP
rs1445748765 2228 dbSNP
rs1470152132 2230 dbSNP
rs1266421663 2237 dbSNP
rs77896706 2238 dbSNP
rs1302124261 2240 dbSNP
rs78204529 2240 dbSNP
rs1362478725 2241 dbSNP
rs1401594850 2242 dbSNP
rs1280379216 2246 dbSNP
rs1319587691 2247 dbSNP
rs1308635570 2249 dbSNP
rs1240305674 2281 dbSNP
rs1375479539 2286 dbSNP
rs921404577 2290 dbSNP
rs1316331305 2293 dbSNP
rs1218198353 2295 dbSNP
rs931501423 2304 dbSNP
rs984299791 2314 dbSNP
rs556475596 2320 dbSNP
rs1292757900 2340 dbSNP
rs991815508 2341 dbSNP
rs372752565 2342 dbSNP
rs908808925 2350 dbSNP
rs1348405241 2357 dbSNP
rs916240532 2362 dbSNP
rs1420452340 2363 dbSNP
rs78911337 2369 dbSNP
rs1435434922 2376 dbSNP
rs1268622705 2379 dbSNP
rs1036418009 2383 dbSNP
rs778662065 2384 dbSNP
rs1216880719 2389 dbSNP
rs1287770227 2389 dbSNP
rs745310828 2399 dbSNP
rs59929322 2400 dbSNP
rs1477302639 2407 dbSNP
rs930142149 2422 dbSNP
rs189001409 2423 dbSNP
rs1047239750 2428 dbSNP
rs1300342043 2431 dbSNP
rs891409070 2437 dbSNP
rs111927141 2438 dbSNP
rs767323742 2440 dbSNP
rs1467608238 2441 dbSNP
rs894273853 2445 dbSNP
rs1421399910 2449 dbSNP
rs899831579 2455 dbSNP
rs1011955599 2458 dbSNP
rs539406485 2461 dbSNP
rs1021722964 2464 dbSNP
rs1011423357 2466 dbSNP
rs1296140316 2470 dbSNP
rs1194752760 2473 dbSNP
rs1487775407 2477 dbSNP
rs1339536410 2478 dbSNP
rs967841343 2484 dbSNP
rs1345066438 2485 dbSNP
rs1255406210 2491 dbSNP
rs1021501339 2492 dbSNP
rs146393611 2496 dbSNP
rs758558507 2496 dbSNP
rs112458943 2497 dbSNP
rs200132281 2501 dbSNP
rs575730658 2501 dbSNP
rs112681124 2502 dbSNP
rs1397903443 2502 dbSNP
rs1278583074 2508 dbSNP
rs1464996841 2510 dbSNP
rs1355079997 2512 dbSNP
rs1020021516 2514 dbSNP
rs1284340178 2519 dbSNP
rs1488128698 2526 dbSNP
rs1199210443 2532 dbSNP
rs992034833 2534 dbSNP
rs916444078 2537 dbSNP
rs965421870 2544 dbSNP
rs1189181084 2547 dbSNP
rs1442549403 2554 dbSNP
rs1476779025 2555 dbSNP
rs1190159933 2560 dbSNP
rs1459063161 2561 dbSNP
rs1258580536 2572 dbSNP
rs138616332 2574 dbSNP
rs746915487 2577 dbSNP
rs142708767 2578 dbSNP
rs760318591 2584 dbSNP
rs1341234110 2585 dbSNP
rs555233602 2587 dbSNP
rs1405730154 2591 dbSNP
rs540541426 2596 dbSNP
rs1351800079 2602 dbSNP
rs1434527117 2604 dbSNP
rs1403145560 2606 dbSNP
rs763672836 2610 dbSNP
rs1302791817 2612 dbSNP
rs560548751 2619 dbSNP
rs776239533 2627 dbSNP
rs1398537340 2634 dbSNP
rs891203358 2640 dbSNP
rs113614096 2645 dbSNP
rs1377662381 2649 dbSNP
rs961914741 2650 dbSNP
rs1472922799 2651 dbSNP
rs982397126 2652 dbSNP
rs1238763431 2657 dbSNP
rs1353510239 2658 dbSNP
rs1456321716 2664 dbSNP
rs577202586 2667 dbSNP
rs1210146681 2668 dbSNP
rs1357348386 2669 dbSNP
rs1283795774 2675 dbSNP
rs1243919015 2676 dbSNP
rs1379200288 2680 dbSNP
rs1310701217 2681 dbSNP
rs929694016 2685 dbSNP
rs938362340 2692 dbSNP
rs1292420006 2696 dbSNP
rs1055517146 2703 dbSNP
rs1406275109 2713 dbSNP
rs915655431 2717 dbSNP
rs761698596 2720 dbSNP
rs1449539157 2721 dbSNP
rs770982895 2722 dbSNP
rs1389633800 2731 dbSNP
rs546196718 2741 dbSNP
rs1421063111 2742 dbSNP
rs1380363647 2755 dbSNP
rs1220301975 2761 dbSNP
rs1437755890 2762 dbSNP
rs1042894251 2773 dbSNP
rs982978891 2774 dbSNP
rs572113371 2779 dbSNP
rs1450790090 2781 dbSNP
rs1480443456 2783 dbSNP
rs903048208 2784 dbSNP
rs944312534 2785 dbSNP
rs1286829547 2794 dbSNP
rs1239464406 2798 dbSNP
rs1039961148 2803 dbSNP
rs1437685849 2807 dbSNP
rs1330883479 2810 dbSNP
rs1300972181 2817 dbSNP
rs753363806 2817 dbSNP
rs900052135 2832 dbSNP
rs999150700 2835 dbSNP
rs1043432064 2845 dbSNP
rs1040985998 2849 dbSNP
rs1157562072 2858 dbSNP
rs1417294032 2862 dbSNP
rs1176766960 2867 dbSNP
rs147322329 2891 dbSNP
rs996866582 2905 dbSNP
rs1477607561 2906 dbSNP
rs1030831683 2910 dbSNP
rs1028316875 2912 dbSNP
rs9817167 2918 dbSNP
rs1403824373 2927 dbSNP
rs1216051077 2928 dbSNP
rs1005618586 2931 dbSNP
rs1015684825 2939 dbSNP
rs1281436944 2940 dbSNP
rs961584010 2945 dbSNP
rs969688331 2946 dbSNP
rs973790306 2949 dbSNP
rs548411907 2950 dbSNP
rs1281778833 2952 dbSNP
rs982731380 2957 dbSNP
rs373625083 2958 dbSNP
rs1027056126 2960 dbSNP
rs1340795146 2961 dbSNP
rs375003758 2964 dbSNP
rs1428122927 2965 dbSNP
rs774647725 2967 dbSNP
rs1360375124 2969 dbSNP
rs982529186 2971 dbSNP
rs759735054 2972 dbSNP
rs527601368 2976 dbSNP
rs947108082 2981 dbSNP
rs767703331 2983 dbSNP
rs1042842619 2988 dbSNP
rs1484969277 2996 dbSNP
rs924417078 3000 dbSNP
rs1239300383 3006 dbSNP
rs371946496 3011 dbSNP
rs555514497 3011 dbSNP
rs547411243 3012 dbSNP
rs1043095861 3014 dbSNP
rs1200959422 3017 dbSNP
rs1319027999 3019 dbSNP
rs570705884 3023 dbSNP
rs563780838 3024 dbSNP
rs1041326877 3028 dbSNP
rs181425877 3042 dbSNP
rs934623423 3059 dbSNP
rs1284306766 3073 dbSNP
rs1446584559 3078 dbSNP
rs1057153388 3081 dbSNP
rs996760188 3083 dbSNP
rs186326126 3096 dbSNP
rs895876518 3104 dbSNP
rs139395306 3105 dbSNP
rs888458146 3114 dbSNP
rs1182544461 3115 dbSNP
rs1416179747 3115 dbSNP
rs1444052922 3117 dbSNP
rs1458752526 3120 dbSNP
rs1196179457 3121 dbSNP
rs1458558842 3122 dbSNP
rs141521144 3124 dbSNP
rs1005567836 3128 dbSNP
rs1257822293 3132 dbSNP
rs1236986938 3134 dbSNP
rs1023872009 3135 dbSNP
rs1202811770 3139 dbSNP
rs371967934 3144 dbSNP
rs145157394 3146 dbSNP
rs201874843 3147 dbSNP
rs1227285340 3153 dbSNP
rs1379940470 3164 dbSNP
rs1189459288 3172 dbSNP
rs1311451368 3172 dbSNP
rs553138155 3177 dbSNP
rs1375973905 3182 dbSNP
rs1296271056 3185 dbSNP
rs1459208844 3186 dbSNP
rs1416308205 3197 dbSNP
rs1351887667 3202 dbSNP
rs752867060 3204 dbSNP
rs1015632558 3208 dbSNP
rs961808972 3209 dbSNP
rs1424159526 3219 dbSNP
rs568494920 3225 dbSNP
rs1003706054 3227 dbSNP
rs1035637026 3233 dbSNP
rs982413207 3233 dbSNP
rs1440877094 3236 dbSNP
rs1467283644 3243 dbSNP
rs1168651459 3244 dbSNP
rs1175896441 3245 dbSNP
rs1489651660 3255 dbSNP
rs1395792456 3257 dbSNP
rs369776931 3269 dbSNP
rs959630986 3270 dbSNP
rs1356756018 3279 dbSNP
rs965104374 3280 dbSNP
rs975635207 3297 dbSNP
rs991099172 3319 dbSNP
rs1352927070 3321 dbSNP
rs375343380 3324 dbSNP
rs1022608601 3330 dbSNP
rs1304760040 3337 dbSNP
rs1388366839 3358 dbSNP
rs1368023250 3360 dbSNP
rs1339140267 3365 dbSNP
rs1292672525 3368 dbSNP
rs749974757 3371 dbSNP
rs1404573386 3372 dbSNP
rs761244108 3375 dbSNP
rs1414532405 3376 dbSNP
rs1420357465 3377 dbSNP
rs1363765020 3378 dbSNP
rs968392410 3382 dbSNP
rs190828423 3383 dbSNP
rs1216353352 3392 dbSNP
rs969036128 3407 dbSNP
rs375296172 3410 dbSNP
rs574900473 3427 dbSNP
rs534387312 3429 dbSNP
rs934675528 3433 dbSNP
rs554195833 3435 dbSNP
rs934441421 3442 dbSNP
rs976613387 3450 dbSNP
rs922453912 3466 dbSNP
rs577462310 3469 dbSNP
rs757932678 3480 dbSNP
rs1312633835 3487 dbSNP
rs1300368412 3490 dbSNP
rs1049650504 3491 dbSNP
rs1300238267 3493 dbSNP
rs1400758684 3498 dbSNP
rs888407189 3503 dbSNP
rs1468037567 3504 dbSNP
rs917356640 3504 dbSNP
rs1378681940 3523 dbSNP
rs1176190190 3525 dbSNP
rs1478933434 3526 dbSNP
rs941373057 3527 dbSNP
rs1037472785 3533 dbSNP
rs1191695012 3534 dbSNP
rs897235253 3539 dbSNP
rs1427494489 3540 dbSNP
rs369405896 3544 dbSNP
rs36092580 3555 dbSNP
rs895329044 3556 dbSNP
rs369906284 3567 dbSNP
rs1201631550 3571 dbSNP
rs562827709 3572 dbSNP
rs1262405195 3573 dbSNP
rs1201574516 3576 dbSNP
rs1022558364 3586 dbSNP
rs1048353173 3588 dbSNP
rs1219497731 3593 dbSNP
rs576612255 3594 dbSNP
rs374087448 3595 dbSNP
rs1397810056 3596 dbSNP
rs1403603735 3597 dbSNP
rs1336614020 3598 dbSNP
rs978417905 3599 dbSNP
rs758084828 3600 dbSNP
rs1019276330 3605 dbSNP
rs562198608 3608 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions C8166
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3 ...

- Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' ucucguucuggggcaGAGAUUu 5'
                         |||||| 
Target 5' aaaguauugaaccaaCUCUAAa 3'
7 - 28
Article - Whisnant AW; Bogerd HP; Flores O; Ho P; et al.
- mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_001199957 | 3UTR | CUGUAUUAUUGAGGGGCAACUCAGGAUUUUAAGUUCCAUAAAGUAUUGAACCAACUCUAAAAUGUUAACUCCUUAAUAAACAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_001199957 | 3UTR | GGAUUUUAAGUUCCAUAAAGUAUUGAACCAACUCUAAAAUGUUAACUCCUUAAUAAACAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_002492 | 3UTR | AGGGGCAACUCAGGAUUUUAAGUUCCAUAAAGUAUUGAACCAACUCUAAAAUGUUAACUCCUUAAUAAACAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_001199957 | 3UTR | AACUCAGGAUUUUAAGUUCCAUAAAGUAUUGAACCAACUCUAAAAUGUUAACUCCUUAAUAAACAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_001199957 | 3UTR | AGGGGCAACUCAGGAUUUUAAGUUCCAUAAAGUAUUGAACCAACUCUAAAAUGUUAACUCCUUAAUAAACAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_001199957 | 3UTR | AACUCAGGAUUUUAAGUUCCAUAAAGUAUUGAACCAACUCUAAAAUGUUAACUCCUUAAUAAACAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1462572
Method / RBP PAR-CLIP / AGO2
Cell line / Condition C8166 / C8166 NL4-3
Location of target site ENST00000493866.1 | 3UTR | UUCCAUAAAGUAUUGAACCAACUCUAAAAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23592263 / GSE59944
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE38226 Liver fibrosis -0.518 8.1e-3 -0.329 7.3e-2 21 Click to see details
GSE28544 Breast cancer 0.453 1.3e-2 0.479 8.9e-3 24 Click to see details
GSE32688 Pancreatic cancer -0.299 4.8e-2 -0.080 3.3e-1 32 Click to see details
GSE26953 Aortic valvular endothelial cells -0.23 1.4e-1 -0.109 3.1e-1 24 Click to see details
GSE42095 Differentiated embryonic stem cells 0.207 1.7e-1 0.302 8.1e-2 23 Click to see details
GSE28260 Renal cortex and medulla -0.115 3.5e-1 -0.088 3.9e-1 13 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.026 4.5e-1 -0.065 3.8e-1 25 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
186 hsa-miR-1303 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT035871 SOAT1 sterol O-acyltransferase 1 1 1
MIRT035872 FHOD3 formin homology 2 domain containing 3 1 1
MIRT035873 RPL7A ribosomal protein L7a 1 1
MIRT035874 NCAPD2 non-SMC condensin I complex subunit D2 1 1
MIRT035875 RPS8 ribosomal protein S8 1 1
MIRT035876 AHNAK AHNAK nucleoprotein 1 1
MIRT035877 ACTB actin beta 1 1
MIRT035878 DEF8 differentially expressed in FDCP 8 homolog 1 1
MIRT035879 MET MET proto-oncogene, receptor tyrosine kinase 1 1
MIRT035880 MED13 mediator complex subunit 13 1 1
MIRT035881 FAT3 FAT atypical cadherin 3 1 1
MIRT035882 HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 1 1
MIRT035883 RPS16 ribosomal protein S16 1 1
MIRT035884 CDK6 cyclin dependent kinase 6 1 1
MIRT035885 GEMIN5 gem nuclear organelle associated protein 5 1 1
MIRT035886 PITRM1 pitrilysin metallopeptidase 1 1 1
MIRT035887 PRRC2A proline rich coiled-coil 2A 1 1
MIRT035888 KIAA0226 RUN and cysteine rich domain containing beclin 1 interacting protein 1 1
MIRT035889 MLLT6 MLLT6, PHD finger containing 1 1
MIRT035890 EIF3I eukaryotic translation initiation factor 3 subunit I 1 1
MIRT035891 FASN fatty acid synthase 1 1
MIRT035892 LEPREL4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 1 1
MIRT035893 HSCB HscB mitochondrial iron-sulfur cluster cochaperone 1 1
MIRT035894 PSME4 proteasome activator subunit 4 1 1
MIRT035895 FRS2 fibroblast growth factor receptor substrate 2 1 1
MIRT035896 ZNF264 zinc finger protein 264 1 1
MIRT035897 HYLS1 HYLS1, centriolar and ciliogenesis associated 1 1
MIRT035898 USP54 ubiquitin specific peptidase 54 1 1
MIRT035899 L1TD1 LINE1 type transposase domain containing 1 1 1
MIRT035900 OR51E2 olfactory receptor family 51 subfamily E member 2 1 1
MIRT053762 CLDN18 claudin 18 3 1
MIRT060730 RPS3 ribosomal protein S3 2 2
MIRT083986 RAB22A RAB22A, member RAS oncogene family 2 2
MIRT098550 TBPL1 TATA-box binding protein like 1 2 6
MIRT134983 TWF1 twinfilin actin binding protein 1 2 4
MIRT136956 FNDC3A fibronectin type III domain containing 3A 2 2
MIRT222065 PURB purine rich element binding protein B 2 2
MIRT239574 UBN2 ubinuclein 2 2 4
MIRT261820 BUB3 BUB3, mitotic checkpoint protein 2 2
MIRT264698 C11ORF57 chromosome 11 open reading frame 57 2 4
MIRT308476 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT377481 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT442304 NEU3 neuraminidase 3 2 2
MIRT446083 SLC30A10 solute carrier family 30 member 10 2 2
MIRT449606 PRPF4 pre-mRNA processing factor 4 2 2
MIRT453767 NUCB1 nucleobindin 1 2 10
MIRT455603 SRSF3 serine and arginine rich splicing factor 3 2 2
MIRT455913 KIF2C kinesin family member 2C 2 2
MIRT460091 ZYG11B zyg-11 family member B, cell cycle regulator 2 4
MIRT460866 UBE2S ubiquitin conjugating enzyme E2 S 2 2
MIRT461339 NUP133 nucleoporin 133 2 2
MIRT463769 YOD1 YOD1 deubiquitinase 2 2
MIRT466368 THAP1 THAP domain containing 1 2 4
MIRT467168 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT468703 SDHD succinate dehydrogenase complex subunit D 2 2
MIRT469122 RNF126 ring finger protein 126 2 2
MIRT472426 NCBP2 nuclear cap binding protein subunit 2 2 4
MIRT479420 CDKN1B cyclin dependent kinase inhibitor 1B 2 8
MIRT484260 FAM177A1 family with sequence similarity 177 member A1 2 2
MIRT485468 IL6ST interleukin 6 signal transducer 2 10
MIRT490237 H2AFZ H2A histone family member Z 2 6
MIRT491002 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT492127 SUMO2 small ubiquitin-like modifier 2 2 2
MIRT499169 RBPJL recombination signal binding protein for immunoglobulin kappa J region like 2 2
MIRT499825 PCSK9 proprotein convertase subtilisin/kexin type 9 2 8
MIRT501794 NRAS NRAS proto-oncogene, GTPase 2 2
MIRT503441 GINS4 GINS complex subunit 4 2 4
MIRT503688 MAVS mitochondrial antiviral signaling protein 2 5
MIRT506926 IGDCC4 immunoglobulin superfamily DCC subclass member 4 2 6
MIRT511430 HOXA10 homeobox A10 2 6
MIRT512415 LAYN layilin 2 4
MIRT513791 NIPAL3 NIPA like domain containing 3 2 4
MIRT516163 NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 2 4
MIRT516513 PARK2 parkin RBR E3 ubiquitin protein ligase 2 2
MIRT516915 HINFP histone H4 transcription factor 2 2
MIRT517102 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT517350 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT518019 ABHD15 abhydrolase domain containing 15 2 2
MIRT520945 SRSF10 serine and arginine rich splicing factor 10 2 2
MIRT525250 RNF213 ring finger protein 213 2 2
MIRT530634 PPIC peptidylprolyl isomerase C 2 4
MIRT530671 CHRNB1 cholinergic receptor nicotinic beta 1 subunit 2 4
MIRT531563 ILDR1 immunoglobulin like domain containing receptor 1 2 2
MIRT538205 CYR61 cysteine rich angiogenic inducer 61 2 2
MIRT538419 COLEC10 collectin subfamily member 10 2 2
MIRT541964 ZNF485 zinc finger protein 485 2 2
MIRT543088 KNSTRN kinetochore localized astrin/SPAG5 binding protein 2 2
MIRT543257 ZNF662 zinc finger protein 662 2 2
MIRT543589 KIAA1549 KIAA1549 2 2
MIRT543955 RNF20 ring finger protein 20 2 2
MIRT544043 C9orf64 chromosome 9 open reading frame 64 2 4
MIRT548064 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT548240 FBXW7 F-box and WD repeat domain containing 7 2 2
MIRT548442 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 2
MIRT548623 DAZAP1 DAZ associated protein 1 2 4
MIRT548770 COLEC12 collectin subfamily member 12 2 2
MIRT549506 HDDC2 HD domain containing 2 2 4
MIRT551924 AKAP8 A-kinase anchoring protein 8 2 4
MIRT555656 PGRMC1 progesterone receptor membrane component 1 2 2
MIRT556286 MAP3K5 mitogen-activated protein kinase kinase kinase 5 2 2
MIRT557012 HOXD13 homeobox D13 2 4
MIRT563907 CLSPN claspin 2 2
MIRT565527 SON SON DNA binding protein 2 2
MIRT568000 COMMD2 COMM domain containing 2 2 2
MIRT569831 PLA2G16 phospholipase A2 group XVI 2 4
MIRT573905 PARP1 poly(ADP-ribose) polymerase 1 2 2
MIRT616589 KLHL9 kelch like family member 9 2 2
MIRT617137 ZNF556 zinc finger protein 556 2 2
MIRT617400 API5 apoptosis inhibitor 5 2 2
MIRT617455 CCS copper chaperone for superoxide dismutase 2 2
MIRT617799 ZNF793 zinc finger protein 793 2 2
MIRT618190 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT618303 GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 2 2
MIRT618329 ZNF813 zinc finger protein 813 2 2
MIRT618820 PHF20 PHD finger protein 20 2 2
MIRT619153 PPDPF pancreatic progenitor cell differentiation and proliferation factor 2 2
MIRT619530 ZNF708 zinc finger protein 708 2 2
MIRT619849 KIR3DX1 killer cell immunoglobulin like receptor, three Ig domains X1 2 2
MIRT620806 SLC26A2 solute carrier family 26 member 2 2 2
MIRT621312 YIPF4 Yip1 domain family member 4 2 2
MIRT621358 GUCA1B guanylate cyclase activator 1B 2 2
MIRT621366 ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 2 2
MIRT621547 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT621883 TAOK1 TAO kinase 1 2 2
MIRT622451 RNF19B ring finger protein 19B 2 2
MIRT623404 KREMEN1 kringle containing transmembrane protein 1 2 2
MIRT623587 IPO9 importin 9 2 2
MIRT623974 FAM63A MINDY lysine 48 deubiquitinase 1 2 2
MIRT624086 DPP8 dipeptidyl peptidase 8 2 2
MIRT624108 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT632486 RNF8 ring finger protein 8 2 2
MIRT634057 PLIN3 perilipin 3 2 2
MIRT634657 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT640682 MCUR1 mitochondrial calcium uniporter regulator 1 2 2
MIRT641242 CENPN centromere protein N 2 2
MIRT642260 ZNF677 zinc finger protein 677 2 2
MIRT642954 RELA RELA proto-oncogene, NF-kB subunit 2 2
MIRT644326 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT644632 ICA1L islet cell autoantigen 1 like 2 2
MIRT645721 POLR3A RNA polymerase III subunit A 2 2
MIRT647850 LYPLA1 lysophospholipase I 2 2
MIRT649281 NEK8 NIMA related kinase 8 2 2
MIRT650038 VHL von Hippel-Lindau tumor suppressor 2 2
MIRT650354 RRP36 ribosomal RNA processing 36 2 2
MIRT651144 ZNF384 zinc finger protein 384 2 2
MIRT651778 UTP6 UTP6, small subunit processome component 2 2
MIRT652576 TLCD2 TLC domain containing 2 2 2
MIRT654621 PTPRJ protein tyrosine phosphatase, receptor type J 2 2
MIRT656023 MYO5A myosin VA 2 2
MIRT656105 MSRB3 methionine sulfoxide reductase B3 2 2
MIRT657749 GMEB1 glucocorticoid modulatory element binding protein 1 2 2
MIRT657924 GATSL2 cytosolic arginine sensor for mTORC1 subunit 2 2 2
MIRT658848 DUSP19 dual specificity phosphatase 19 2 2
MIRT659100 DENND6A DENN domain containing 6A 2 2
MIRT659153 DCX doublecortin 2 2
MIRT660870 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT661941 FAHD1 fumarylacetoacetate hydrolase domain containing 1 2 2
MIRT663577 C10orf32 BLOC-1 related complex subunit 7 2 2
MIRT664625 WDPCP WD repeat containing planar cell polarity effector 2 4
MIRT666562 RHOBTB3 Rho related BTB domain containing 3 2 2
MIRT669992 GPR156 G protein-coupled receptor 156 2 4
MIRT670445 RSBN1L round spermatid basic protein 1 like 2 2
MIRT670853 IFNAR1 interferon alpha and beta receptor subunit 1 2 4
MIRT671942 SPPL3 signal peptide peptidase like 3 2 2
MIRT674269 LMOD3 leiomodin 3 2 2
MIRT674424 MIOX myo-inositol oxygenase 2 4
MIRT674982 ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C1 (subunit 9) 2 2
MIRT675038 BACE2 beta-site APP-cleaving enzyme 2 2 4
MIRT675309 C2orf68 chromosome 2 open reading frame 68 2 2
MIRT675641 TTPAL alpha tocopherol transfer protein like 2 2
MIRT688688 CPS1 carbamoyl-phosphate synthase 1 2 2
MIRT689369 ZNF101 zinc finger protein 101 2 2
MIRT689605 AKAP6 A-kinase anchoring protein 6 2 2
MIRT691715 LARS leucyl-tRNA synthetase 2 2
MIRT695473 TRAT1 T-cell receptor associated transmembrane adaptor 1 2 2
MIRT695530 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 2
MIRT695878 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT696586 ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2 2
MIRT703007 HEATR5A HEAT repeat containing 5A 2 2
MIRT707942 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 2
MIRT709765 GPR183 G protein-coupled receptor 183 2 2
MIRT710332 ZNF669 zinc finger protein 669 2 2
MIRT713249 ZFP30 ZFP30 zinc finger protein 2 2
MIRT716613 RBM18 RNA binding motif protein 18 2 2
MIRT733414 BAG2 BCL2 associated athanogene 2 2 0
MIRT756135 THSD7A thrombospondin type 1 domain containing 7A 3 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-1 Anthocyanin NULL 145858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Caffeic acid NULL 689043 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Catechin approved 9064 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Ferulic acid NULL 445858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Hesperidin NULL 10621 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Quercetin NULL 5280343 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Galactose NULL 6036 Quantitative real-time PCR lens 22736950 2012 up-regulated
miR-1 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Quantitative real-time PCR myocardial differentiation of mouse ES cells 19521018 2009 down-regulated
miR-1 Sulfonyl-hydrazone-1 (SHZ) NULL NULL Quantitative real-time PCR Murine broblast-derived Induced pluripotent stem cells 21445862 2011 up-regulated
miR-1 Cocaine NULL 446220 Next-generation sequencing ventral striatum 21708909 2011 up-regulated
miR-1 Atorvastatin approved 60823 Quantitative real-time PCR Cardiomyocyte 23860036 2013 down-regualted
miR-1 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-1 Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 Palmitic acid approved 985 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 17beta-estradiol (E2) approved 5757 Microarray MCF-7AKT breast cancer cells 19528081 2009 down-regulated
miR-1 Essential amino acids (EAA) NULL NULL Quantitative real-time PCR skeletal muscle of young adults 19828686 2009 up-regulated
miR-1 Hydrogen peroxide (H2O2) NULL 784 Quantitative real-time PCR Human umbilical vein endothelial cells 21527937 2011 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Microarray apoptosis-resistant breast cancer cells 21971930 2011 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-1 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-1 Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR cardia 22889704 2012 up-regulated
miR-1 Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-1 Quinidine approved 441074 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 up-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 down-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR post-infarction rat cardiomyocytes 21220930 2011 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miR-1 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-1303 Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer cell line (RKO)
hsa-miR-1303 Oxaliplatin 6857599 NSC266046 approved resistant High Colorectal Cancer cell line (HT-29)
hsa-miR-1303 Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-1303 Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-1303 Rituximab sensitive High Diffuse Large B-Cell Lymphoma cell line (DB, NU-DHL-1, NU-DUL-1, MC-116, SU-DHL-4, SU-DHL-5, FARAGE, HBL-1, OCI-Ly3, OCI-Ly7, OCI-Ly8, OCI-Ly19, RIVA, SU-DHL-8, U2932)
hsa-miR-1303 Etoposide 36462 NSC141540 approved resistant High Colorectal Cancer cell line (HCT8)
hsa-miR-1303 Doxorubicin 31703 NSC123127 approved resistant High Colorectal Cancer cell line (HCT8)
hsa-miR-1303 Vinorelbine 44424639 approved resistant High Colorectal Cancer cell line (HCT8)
hsa-miR-1303 Vincristine 5978 approved resistant High Colorectal Cancer cell line (HCT8)
hsa-miR-1303 Paclitaxel 36314 NSC125973 approved resistant High Colorectal Cancer cell line (HCT8)
hsa-mir-1303 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-mir-1303 Cisplatin 5460033 NSC119875 approved resistant cell line (W1)
hsa-mir-1303 Topotecan 60699 NSC609699 approved resistant cell line (W1)
hsa-mir-1303 Androstenedione+Letrozole resistant cell line (MCF-7)
hsa-miR-1303 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-1303 Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-1303 Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-1303 Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-1303 Palbociclib 5330286 NSC758247 approved resistant tissue (breast cancer)
hsa-miR-1303 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-1303 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-1303 Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-miR-1303 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-1303 Cisplatin 5460033 NSC119875 approved resistant cell line (CP20)
hsa-miR-1303 Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)
hsa-miR-1303 Oxaliplatin 6857599 NSC266046 approved sensitive cell line (IGROV-1)
hsa-miR-1303 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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